Table 9 Classification of unknown genes

GENE SYMBOL	GENE NAME	PROBE NO (Iyer et al.)	ACCESSION NUMBER	PREDICTIONS FOR THE 23 BROAD CELLULAR PROCESSES USED FOR LEARNING
LOC80298	transcription termination factor-like protein	1	W95909	cell surface receptor linked signal transduction, cell cycle
EST, unclustered		3	AA044605	protein metabolism and modification, developmental processes
	ESTs	6	AA059077	cell proliferation, protein metabolism and modification, cell motility, developmental processes
EST, unclustered		7	AA035657	protein metabolism and modification, developmental processes
KIAA0455	KIAA0455 gene product	10	H19324	cell death, blood coagulation
	Homo sapiens cDNA FLJ13545 fis, clone PLACE1006867	13	W89018	lipid metabolism
KIAA1391	KIAA1391 protein	16	H28360	cell surface receptor linked signal transduction, transcription
	ESTs	17	H16592	cell motility, cell death
	ESTs	18	W78151	cell death, blood coagulation
EST, unclustered		20	H14500	cell death
	Homo sapiens clone 23645 mRNA sequence	23	N75026	cell death, blood coagulation
	Homo sapiens cDNA: FLJ21482 fis, clone COL05135	24	R87731	cell death, blood coagulation
EST, unclustered		26	H61274	cell death, blood coagulation
	Homo sapiens mRNA; cDNA DKFZp761K2024 (from clone DKFZp761K2024)	27	N63445	cell death, blood coagulation
	Homo sapiens mRNA; cDNA DKFZp564L0822 (from clone DKFZp564L0822)	28	W69445	cell surface receptor linked signal transduction, cell death, blood coagulation
	Homo sapiens mRNA; cDNA DKFZp586I1823 (from clone DKFZp586I1823)	29, 31	R60336, H15535	lipid metabolism, transcription
KIAA1628	KIAA1628 protein	30	N53427	lipid metabolism, transcription
	ESTs	32	R60731	lipid metabolism, transcription
FLJ20643	hypothetical protein FLJ20643	34	AA018444	cell death, blood coagulation, oncogenesis
KIAA0993	KIAA0993 protein	35	AA031778	cell surface receptor linked signal transduction, transcription, oncogenesis
EST, unclustered		38	W86006	cell proliferation, lipid metabolism, cell adhesion, developmental processes, blood coagulation
LOC55977	hypothetical protein 24636	39	AA037007	protein metabolism and modification, lipid metabolism, developmental processes, blood coagulation
FLJ10849	hypothetical protein FLJ10849	40	H93791	cell motility, cell adhesion, developmental processes, cell surface receptor linked signal transduction
KIAA0451	KIAA0451 gene product	41	AA011682	lipid metabolism, transcription
	ESTs	42	R46079	lipid metabolism, transcription
	ESTs, Weakly similar to FAT DROME CADHERIN-RELATED TUMOR SUPPRESSOR PRECURSOR [D.melanogaster]	43	H05133	cell surface receptor linked signal transduction, transcription
FLJ00026	hypothetical protein FLJ00026	44	N38765	lipid metabolism, transcription
	ESTs	45	AA057433	lipid metabolism, transcription
	ESTs	46	N52170	cell adhesion, transcription
ULK2	unc-51 (C. elegans)-like kinase 2	49	R05458	lipid metabolism, transcription
	Homo sapiens cDNA FLJ31992 fis, clone NT2RP7009149, weakly similar to GLUCOSE TRANSPORTER TYPE 2, LIVER	51, 81	R59736, N20862	developmental processes, lipid metabolism, cell adhesion
	Homo sapiens mRNA; cDNA DKFZp564A2164 (from clone DKFZp564A2164)	52	N50955	lipid metabolism, cell adhesion, developmental processes
	ESTs, Weakly similar to S65824 reverse transcriptase homolog [H.sapiens]	54	R24284	cell adhesion, developmental processes
	Homo sapiens cDNA FLJ12028 fis, clone HEMBB1001850	56	H01236	lipid metabolism, developmental processes, oncogenesis
	ESTs	57	N74313	cell death
FLJ11273	hypothetical protein FLJ11273	58	H85971	cell death, transcription
PP5395	hypothetical protein PP5395	62	N26801	developmental processes, cell death, blood coagulation
EST, unclustered		63	AA036987	cell proliferation
	Homo sapiens mRNA; cDNA DKFZp727C191 (from clone DKFZp727C191)	65	W84708	cell surface receptor linked signal transduction, transcription
EST, unclustered		67	AA029996	cell proliferation, lipid metabolism, developmental processes
AD036	AD036 protein	68	N95180	cell motility, cell adhesion
FLJ10217	oxysterol-binding protein-related protein 1	69	W72188	cell death, blood coagulation
EST, unclustered		71	H66595	amino-acid and derivative metabolism, transcription
	Homo sapiens, clone IMAGE:3140802, mRNA	75	W79450	lipid metabolism, cell cycle, oncogenesis
KIAA0878	KIAA0878 protein	77	AA037718	cell proliferation, intracellular signalling cascade, oncogenesis
MAC30	hypothetical protein	79	N33221	lipid metabolism, transcription, oncogenesis
	Homo sapiens cDNA: FLJ21954 fis, clone HEP05155	83	AA047641	transport, lipid metabolism, developmental processes, cell death
LOC57100	organic cation transporter	84	AA025786	transcription
	ESTs	87	AA057199	cell motility, cell adhesion, developmental processes
	Homo sapiens cDNA FLJ20767 fis, clone COL06986	88	AA047419	cell motility, developmental processes, defense (immune) response, oncogenesis
	Homo sapiens cDNA FLJ31683 fis, clone NT2RI2005353	90	AA040147	cell proliferation, transcription, oncogenesis
	Homo sapiens cDNA FLJ10229 fis, clone HEMBB1000136	91	AA036947	protein metabolism and modification, cell surface receptor linked signal transduction, transcription, oncogenesis
	Homo sapiens mRNA; cDNA DKFZp586N012 (from clone DKFZp586N012)	94	W67250	cell adhesion, developmental processes
FLJ14525	hypothetical protein FLJ14525	97	AA024914	cell surface receptor linked signal transduction, blood coagulation, transcription
EST, unclustered		98	T65590	lipid metabolism
BM-002	hypothetical protein	105	W95464	cell organization and biogenesis, cell cycle, DNA metabolism
FLJ22794	hypothetical protein FLJ22794	106	W04611	cell organization and biogenesis, cell cycle
KIAA1376	KIAA1376 protein	108	R33609	DNA metabolism, transcription
	ESTs	111	AA042944	cell cycle, DNA metabolism, transcription
DKFZP586D2223	DKFZP586D2223 protein	112	W74140	transport, cell cycle
RAP140	KIAA1105 protein	113	N38985	transport, cell organization and biogenesis, cell cycle
FLJ10971	hypothetical protein FLJ10971	114	N64669	cell surface receptor linked signal transduction, cell death, oncogenesis
	Homo sapiens mRNA; cDNA DKFZp547M073 (from clone DKFZp547M073)	115	T72562	transport, developmental processes, cell cycle
ZNF302	zinc finger protein 302	116	N66534	cell proliferation
	Homo sapiens clones 24622 and 24623 mRNA sequence	117	H29047	cell cycle, DNA metabolism
P38IP	transcription factor (p38 interacting protein)	118	R51510	cell death, cell cycle, intracellular signalling cascade, DNA metabolism
FLJ20008	hypothetical protein FLJ20008	119	H00168	lipid metabolism, DNA metabolism
	Homo sapiens cDNA FLJ30816 fis, clone FEBRA2001571	120	AA024606	cell proliferation, cell adhesion, defense (immune) response, blood coagulation
KIAA0643	KIAA0643 protein	121	R56644	stress response, lipid metabolism, DNA metabolism
	Homo sapiens mRNA; cDNA DKFZp566P1124 (from clone DKFZp566P1124)	122	H62361	protein metabolism and modification, lipid metabolism
NEDD4L	ubiquitin-protein ligase NEDD4-like	126	R43846	lipid metabolism, oncogenesis
FLJ10283	hypothetical protein FLJ10283	127	R43729	transport, cell cycle, DNA metabolism
EST, unclustered		129	AA005169	lipid metabolism, transcription
EST, unclustered		131	N51744	cell cycle, DNA metabolism, transcription
FLJ10287	hypothetical protein	133	H83658	transcription
SULT4A1	sulfortranferase family 4A, member 1	134	N63574	lipid metabolism, transcription
BBS2	Bardet-Biedl syndrome 2	136, 166	N64209, W92305	cell proliferation, intracellular signalling cascade, transcription, oncogenesis, cell death, blood coagulation
	Homo sapiens cDNA FLJ12052 fis, clone HEMBB1002042, moderately similar to CYTOCHROME P450 4C1 (EC 1.14.14.1)	137	N72289	cell death, blood coagulation
DMWD	dystrophia myotonica-containing WD repeat motif	138	W71999	cell surface receptor linked signal transduction, transcription
KIAA0447	KIAA0447 gene product	140	W81522	cell cycle, transcription
	ESTs	143	AA029451	cell surface receptor linked signal transduction, transcription
WW45	WW Domain-Containing Gene	144, 200	H25014, H88517	cell surface receptor linked signal transduction, transcription
MGC12904	hypothetical protein MGC12904	147	AA007609
LPIN1	lipin 1	149	W93986	cell cycle, blood coagulation, DNA metabolism, transcription
	Homo sapiens mRNA; cDNA DKFZp434D0215 (from clone DKFZp434D0215); partial cds	151	AA045561	cell surface receptor linked signal transduction, transcription
KIAA0977	KIAA0977 protein	154	AA007439	cell death, intracellular signalling cascade, oncogenesis
	Homo sapiens mRNA; cDNA DKFZp761M0223 (from clone DKFZp761M0223)	161	N64806	cell organization and biogenesis, cell cycle, transcription
MGC16169	hypothetical protein MGC16169	162	N50448	transcription
EST, unclustered		165	H08856	cell death, intracellular signalling cascade
	Homo sapiens mRNA; cDNA DKFZp586J2118 (from clone DKFZp586J2118)	169	N69835	lipid metabolism, transcription
Rab11-FIP2	KIAA0941 protein	170	AA045506	intracellular signalling cascade, DNA metabolism, transcription, oncogenesis
	ESTs, Weakly similar to ubiquitous TPR motif, Y isoform [H.sapiens]	171	AA004712	blood coagulation
AHRR	KIAA1234 protein	172	W93502	lipid metabolism, DNA metabolism
	Homo sapiens, clone IMAGE:3846772, mRNA, partial cds	174	W87769	cell proliferation, cell motility, cell adhesion, developmental processes
	Homo sapiens PRO2751 mRNA, complete cds	175	N75545	cell proliferation
EST, unclustered		176	AA025835	cell proliferation, protein metabolism and modification, cell organization and biogenesis, cell death, amino-acid and derivative metabolism
	ESTs	178	AA056431	transport, cell organization and biogenesis, cell cycle
	Homo sapiens mRNA; cDNA DKFZp547K204 (from clone DKFZp547K204)	180	AA021607	cell surface receptor linked signal transduction, DNA metabolism, transcription
EST, unclustered		181	H86088	lipid metabolism, transcription
DKFZP434P0721	similar to mouse Xrn1 / Dhm2 protein	182	N47794	cell organization and biogenesis, cell cycle, blood coagulation, DNA metabolism, transcription
LOC58486	transposon-derived Buster1 transposase-like protein	183	AA016001	lipid metabolism, DNA metabolism, transcription
	Homo sapiens cDNA FLJ12793 fis, clone NT2RP2002033	184	N73953	transport, lipid metabolism
	ESTs	185	H05758	cell death
	ESTs	186	AA018594	protein metabolism and modification, transcription, oncogenesis
KIAA0786	latrophilin	187	W74533	transcription, oncogenesis
HCGVIII-1	HCGVIII-1 protein	190	H77631	stress response, protein metabolism and modification, developmental processes, cell surface receptor linked signal transduction
	ESTs	191	R70903	oncogenesis
DKFZP434E2318	hypothetical protein DKFZp434E2318	193	H06287	lipid metabolism, DNA metabolism, transcription
	ESTs	194	R43550	lipid metabolism, DNA metabolism, transcription
	ESTs	195	H92076	lipid metabolism, transcription
	ESTs	197	R73580	lipid metabolism, transcription
SIAH1	seven in absentia (Drosophila) homolog 1	198	R62600	lipid metabolism, transcription
	ESTs	199	H14569	cell surface receptor linked signal transduction, transcription
FLJ22054	hypothetical protein FLJ22054	201	T89077	cell cycle
KIAA0923	KIAA0923 protein	202, 203, 205, 210	H29270, R43139, H92461, H20847	oncogenesis, lipid metabolism, transcription, intracellular signalling cascade
FLJ11896	hypothetical protein FLJ11896	209	N63536	cell surface receptor linked signal transduction, transcription
	ESTs	212	N80164	cell organization and biogenesis, cell cycle, DNA metabolism
	ESTs, Weakly similar to 1207289A reverse transcriptase related protein [H.sapiens]	213	R37278	cell cycle, transcription
FLJ11040	hypothetical protein FLJ11040	214	AA011444	cell cycle, DNA metabolism, transcription
KIAA0602	KIAA0602 protein	216	T98860	lipid metabolism, DNA metabolism, transcription, oncogenesis
KIAA1799	KIAA1799 protein	222	H11911	cell surface receptor linked signal transduction, transcription
	Homo sapiens, clone IMAGE:3677155, mRNA	223	H15273	lipid metabolism, transcription
	ESTs, Weakly similar to T15332 hypothetical protein B0336.5 - Caenorhabditis elegans [C.elegans]	224	W15407	transport, protein metabolism and modification, protein targeting
UACA	uveal autoantigen with coiled-coil domains and ankyrin repeats	225	N66980	cell surface receptor linked signal transduction, cell death, transcription
	Homo sapiens cDNA: FLJ22290 fis, clone HRC04405	226	AA028136	DNA metabolism, transcription
	ESTs	227	R51896	cell surface receptor linked signal transduction, transcription
PIST	PDZ/coiled-coil domain binding partner for the rho-family GTPase TC10	228	N68337	stress response, protein metabolism and modification, cell surface receptor linked signal transduction, transcription
KIAA0355	KIAA0355 gene product	230	N62692	transport, stress response, protein metabolism and modification, developmental processes
AUTL1	AUT (S. cerevisiae)-like 1, cysteine endopeptidase	232	H27880	cell surface receptor linked signal transduction, transcription
	ESTs, Weakly similar to A Chain A, Human Cd69 - Trigonal Form {SUB 82-199 [H.sapiens]	235	N33510	cell surface receptor linked signal transduction, cell cycle, transcription
	ESTs	236	N67562	cell surface receptor linked signal transduction, transcription
	Homo sapiens cDNA FLJ31542 fis, clone NT2RI2000829	239	W73942	protein metabolism and modification, cell surface receptor linked signal transduction, transcription
DC8	DKFZP566O1646 protein	240, 303	AA052967, AA009683	cell surface receptor linked signal transduction, cell cycle, DNA metabolism, transcription, transport
IFIT1	interferon-induced protein with tetratricopeptide repeats 1	244	AA052933	transcription, oncogenesis
KIAA1462	KIAA1462 protein	246	H07905	lipid metabolism, transcription
PTGFRN	prostaglandin F2 receptor negative regulator	249	AA045111	transcription, oncogenesis
	Homo sapiens clone IMAGE:1338238, mRNA sequence	251	T63170	cell motility, transcription
CDA08	hypothetical protein CDA08	252	N36415	protein metabolism and modification, cell surface receptor linked signal transduction, cell death, blood coagulation
	ESTs	254	T91987	DNA metabolism
	ESTs, Weakly similar to B34087 hypothetical protein [H.sapiens]	256	R55334	cell cycle, transcription
EST, unclustered		261	W88695	protein metabolism and modification, cell organization and biogenesis
	Homo sapiens cDNA: FLJ21781 fis, clone HEP00223	262	H17413	cell cycle
ANGPTL2	angiopoietin-like 2	263	W73148	cell proliferation
	ESTs	265	T40920	lipid metabolism, transcription, oncogenesis
MEG3	maternally expressed 3	266	T93776	cell proliferation, protein metabolism and modification, lipid metabolism, transcription
EST, unclustered		274	AA004918	cell proliferation, transcription
H-l(3)mbt-l	H-l(3)mbt-like protein	275	AA026761	cell proliferation, lipid metabolism, transcription, oncogenesis
	ESTs, Highly similar to TNHUA prothymosin alpha [H.sapiens]	281	AA029995	lipid metabolism, blood coagulation
	ESTs, Highly similar to S68855 lanosterol 14alpha-demethylase [H.sapiens]	284	W74235
EST, unclustered		285	AA045739	cell adhesion
ARG99	ARG99 protein	292	H09359	lipid metabolism, developmental processes, oncogenesis
LOC57018	cyclin L ania-6a	293	AA016305	cell proliferation, transcription, oncogenesis
	ESTs, Weakly similar to I60307 beta-galactosidase, alpha peptide - Escherichia coli [E.coli]	294	AA047080	cell proliferation, transcription, oncogenesis
EST, unclustered		296	AA033790	protein metabolism and modification
	ESTs	298	AA021163	cell motility
SMC2L1	SMC2 (structural maintenance of chromosomes 2, yeast)-like 1	301	H04812	cell cycle, DNA metabolism
ANKT	nucleolar protein ANKT	302	R67964	cell cycle
	ESTs	307	N54485	cell proliferation, cell adhesion, defense (immune) response, blood coagulation
KIAA0175	likely ortholog of maternal embryonic leucine zipper kinase	309	W01871	cell cycle, transcription
	Homo sapiens, clone MGC:20276 IMAGE:3844806, mRNA, complete cds	310	AA037511	cell surface receptor linked signal transduction, transcription
KIAA1382	amino acid transporter 2	317	AA034524	cell surface receptor linked signal transduction, cell cycle
	ESTs, Weakly similar to T08599 probable transcription factor CA150 [H.sapiens]	318	AA035263	cell cycle
CNAP1	chromosome condensation-related SMC-associated protein 1	319	N89934	cell surface receptor linked signal transduction, cell cycle, transcription
CKAP2	cytoskeleton associated protein 2	326	T52152	cell cycle, transcription
HSPC150	HSPC150 protein similar to ubiquitin-conjugating enzyme	330	AA004517	cell organization and biogenesis, cell cycle, DNA metabolism
ARL6IP	ADP-ribosylation factor-like 6 interacting protein	337	AA041468	stress response
EST, unclustered		344	AA004917	cell proliferation, protein metabolism and modification, intracellular signalling cascade, transcription, oncogenesis
	Homo sapiens clone 23718 mRNA sequence	346	AA058863	cell proliferation, intracellular signalling cascade, transcription, oncogenesis
EST, unclustered		347	T95837	stress response, protein metabolism and modification, oncogenesis
EST, unclustered		353	R16980	transport, defense (immune) response, circulation
FLJ21661	hypothetical protein FLJ21661	359	AA024572	cell motility, defense (immune) response
KIAA0157	KIAA0157 protein	361	AA004694	cell motility, cell adhesion, defense (immune) response, blood coagulation
MGC5627	hypothetical protein MGC5627	366	N93284	defense (immune) response
TMEPAI	transmembrane, prostate androgen induced RNA	369	AA053251	transport, defense (immune) response, circulation
	Homo sapiens cDNA: FLJ22528 fis, clone HRC12825	373	H26271	transport, stress response, protein metabolism and modification, blood coagulation
KIAA1552	KIAA1552 protein	374	H24396	stress response, protein metabolism and modification, blood coagulation
	ESTs	377	T48819	protein metabolism and modification, cell motility, blood coagulation
EST, unclustered		381	W51763	transport, cell motility, defense (immune) response, blood coagulation
FLJ23476	hypothetical protein FLJ23476	383	H02832	transport, stress response, protein metabolism and modification, cell surface receptor linked signal transduction, defense (immune) response, blood coagulation
HMGE	GrpE-like protein cochaperone	385	AA037156	stress response, protein metabolism and modification
	EST	388	W52295	cell motility, defense (immune) response, blood coagulation
	ESTs	390	H02191	protein metabolism and modification, cell organization and biogenesis, cell cycle
FLJ10830	hypothetical protein FLJ10830	401	AA031267	transport, cell proliferation, protein metabolism and modification, cell motility, defense (immune) response
C21orf25	chromosome 21 open reading frame 25	410	T54874	cell motility, defense (immune) response
G2	G2 protein	411	R16047	cell adhesion, cell cycle, DNA metabolism, protein targeting
DKFZp667O2416	hypothetical protein DKFZp667O2416	417	AA057780	cell cycle
EST, unclustered		418	AA020014	protein metabolism and modification, cell cycle, DNA metabolism
EST, unclustered		419	R99596	stress response, protein metabolism and modification, intracellular signalling cascade
	Human clone 23933 mRNA sequence	420	R39465	cell proliferation
	ESTs	425	H01822	transport, cell motility, cell adhesion, cell organization and biogenesis
EST, unclustered		431	W74639	stress response, protein metabolism and modification
	Homo sapiens clone 24589 mRNA sequence	437	AA054706	cell death, defense (immune) response, transcription
FLJ21079	hypothetical protein FLJ21079	438	R53619	transport, cell motility, cell adhesion, cell organization and biogenesis
EST, unclustered		442	AA032091	cell motility, cell adhesion
	ESTs, Highly similar to SMHU1B metallothionein 1B [H.sapiens]	447	H72723	stress response, protein metabolism and modification, ion homeostasis
	Homo sapiens, Similar to RIKEN cDNA 2300002L21 gene, clone MGC:17528 IMAGE:3458906, mRNA, complete cds	451	AA053259	cell adhesion, cell cycle, DNA metabolism
EST, unclustered		455	W73776	stress response, protein metabolism and modification
	ESTs, Weakly similar to T33110 hypothetical protein C18H7.3 - Caenorhabditis elegans [C.elegans]	461, 462	H85111, H73480	stress response, protein metabolism and modification, blood coagulation, ion homeostasis, cell motility
	ESTs, Highly similar to AF078844 1 hqp0376 protein [H.sapiens]	464	N55459	stress response, cell motility, blood coagulation, ion homeostasis
KIAA0368	KIAA0368 protein	466	H88808	stress response, protein metabolism and modification
KIAA0186	KIAA0186 gene product	469	H48459	stress response, protein metabolism and modification
	Human chromosome 17q21 mRNA clone 1046:1-1	471	R21832	stress response, defense (immune) response, blood coagulation
FLJ20727	hypothetical protein FLJ20727	472	R21877	stress response, ion homeostasis
NDRG2	N-myc downstream-regulated gene 2	487	N90531	stress response, defense (immune) response, blood coagulation
	EST	488	R36703	transport, blood coagulation, circulation
MGC5469	hypothetical protein MGC5469	495	AA057667	cell proliferation, cell surface receptor linked signal transduction, defense (immune) response
ARV1	likely ortholog of yeast ARV1	497	AA056549	lipid metabolism
EST, unclustered		498	N58770	cell proliferation, intracellular signalling cascade, defense (immune) response, transcription, oncogenesis
DKFZP564B167	DKFZP564B167 protein	503	AA034912	cell proliferation, transcription
CRIP2	cysteine-rich protein 2	510	AA045715	cell proliferation, cell surface receptor linked signal transduction, defense (immune) response, transcription
KIAA1409	KIAA1409 protein	514	AA013396	cell proliferation, intracellular signalling cascade, transcription, oncogenesis
EST, unclustered		516	W90037	cell proliferation, intracellular signalling cascade, transcription
RCL	putative c-Myc-responsive	517	W88650	cell proliferation, protein metabolism and modification, intracellular signalling cascade, defense (immune) response