Binding site rules

ndt80(MSE)(1) AND SWI5(1) => SimExpr(YGL116W) OR SimExpr(other) : 16 7

EXPR: (0.210) ndt80(MSE) (P < 0.161) SWI5 (P < 0.000)

ORF SYMBOL P F C TF
YDR042C NO SYMBOL ARG80, ARG81, AZF1, CIN5, CUP9, DIG1, FZF1, GCR2, HAL9, HAP2, HAP4, HAP5, HIR2, HMS1, IXR1, LEU3, MBP1, MCM1, MET31, NRG1, PDR1, RLM1, RME1, ROX1, RTG1, RTG3, SRD1, STE12, SUM1, YAP6, ZAP1
|YCR045C| NO SYMBOL
YJR007W SUI2 translational initiation ->
biosynthesis, protein metabolism translation initiation factor activity ->
translation initiation factor activity ribosome, cytoplasm ->
cytoplasm, ribonucleoprotein complex GLN3, HAP3, HIR1, RCS1
|YBR159W| NO SYMBOL ACE2, ARG81, GCR2, HIR2, LEU3, MOT3, PDR1, PHD1, SKN7, USV1
|YNL196C| NO SYMBOL
YOR338W NO SYMBOL RAP1
YNL034W NO SYMBOL MAC1, MET4, NDD1, RME1
YMR001C CDC5 DNA dependent DNA replication, protein amino acid phosphorylation ->
phosphorus metabolism, cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism protein serine/threonine kinase activity ->
protein serine/threonine kinase activity nucleus, spindle pole, bud neck ->
nucleus, cytoplasm, site of polarized growth (sensu Fungi) NDD1, REB1, SWI6
|YLR154C| RNH203 RLM1
YFR023W PES4 DNA dependent DNA replication ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DIG1, FKH1, FKH2, GLN3, HAP3, MCM1, MSN2, RIM101, RLM1, RTG3, STE12, SUM1, THI2, YAP1
|YMR280C| CAT8 gluconeogenesis, positive regulation of transcription from Pol II promoter ->
alcohol metabolism, monosaccharide metabolism, carbohydrate metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, biosynthesis, energy pathways specific RNA polymerase II transcription factor activity ->
specific RNA polymerase II transcription factor activity nucleus ->
nucleus ABF1, REB1
YFR012W NO SYMBOL DAL81
YOL132W GAS4 cell wall (sensu Fungi) ->
cell wall
YHR124W NDT80 meiosis, transcription ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism transcription factor activity ->
transcription factor activity nuclear chromosome ->
chromosome, nucleus SUM1
YBR069C TAT1 amino acid transport ->
transport amino acid transporter activity ->
amino acid transporter activity plasma membrane ->
plasma membrane CIN5, DAL81, PHD1, SWI4
YKL104C GFA1 cell wall chitin biosynthesis ->
cell organization and biogenesis, biosynthesis, polysaccharide metabolism, carbohydrate metabolism glucosamine-fructose-6-phosphate aminotransferase (isomerizing) activity ->
glucosamine-fructose-6-phosphate aminotransferase (isomerizing) activity REB1
YFR032C NO SYMBOL PUT3, SUM1
YOR214C NO SYMBOL BAS1
YGL116W CDC20 mitotic spindle elongation, ubiquitin-dependent protein catabolism, mitotic metaphase/anaphase transition, mitotic chromosome segregation, cyclin catabolism ->
cell organization and biogenesis, catabolism, cell proliferation, cell cycle, protein metabolism enzyme activator activity ->
enzyme activator activity anaphase-promoting complex ->
nucleus, ubiquitin ligase complex DIG1, FKH2, INO2, INO4, IXR1, MCM1, NDD1
YLR049C NO SYMBOL MBP1, SWI5
|YHL043W| ECM34 cell wall organization and biogenesis ->
cell organization and biogenesis
YPR122W AXL1 axial budding, bud site selection, conjugation with cellular fusion, peptide pheromone maturation ->
asexual reproduction, conjugation, protein metabolism, cell proliferation, cell organization and biogenesis, sexual reproduction metalloendopeptidase activity ->
metalloendopeptidase activity integral to membrane, bud neck, shmoo tip ->
integral to membrane, site of polarized growth (sensu Fungi) CIN5
|YKR005C| NO SYMBOL
Main: cell proliferation (0.50) metalloendopeptidase activity (0.12) nucleus (0.50) SUM1 (0.22)
Score: 0.53 0.00 0.29 0.163
P-value: 2.212E+00 (carbohydrate biosynthesis) 4.226E+00 (transcription regulator activity) 1.310E+00 (bud neck) 4.860E-02 (SUM1)

SFF(1) AND ndt80(MSE)(1) AND MCM1'(1) => SimExpr(YGL116W) OR SimExpr(other) : 9 2

EXPR: (0.176) SFF (P < 0.000) ndt80(MSE) (P < 0.086) MCM1' (P < 0.000)

ORF SYMBOL P F C TF
YNR034W SOL1 tRNA processing ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism YFL044C
YKL096W CWP1 cell wall organization and biogenesis ->
cell organization and biogenesis structural constituent of cell wall ->
structural constituent of cell wall cell wall (sensu Fungi) ->
cell wall RLM1, SMP1, STE12, SWI4
YFR023W PES4 DNA dependent DNA replication ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DIG1, FKH1, FKH2, GLN3, HAP3, MCM1, MSN2, RIM101, RLM1, RTG3, STE12, SUM1, THI2, YAP1
YGL116W CDC20 mitotic spindle elongation, ubiquitin-dependent protein catabolism, mitotic metaphase/anaphase transition, mitotic chromosome segregation, cyclin catabolism ->
cell organization and biogenesis, catabolism, cell proliferation, cell cycle, protein metabolism enzyme activator activity ->
enzyme activator activity anaphase-promoting complex ->
nucleus, ubiquitin ligase complex DIG1, FKH2, INO2, INO4, IXR1, MCM1, NDD1
YJR007W SUI2 translational initiation ->
biosynthesis, protein metabolism translation initiation factor activity ->
translation initiation factor activity ribosome, cytoplasm ->
cytoplasm, ribonucleoprotein complex GLN3, HAP3, HIR1, RCS1
YGL230C NO SYMBOL HIR1, MATa1
YPL255W BBP1 microtubule nucleation ->
cell organization and biogenesis structural constituent of cytoskeleton ->
structural constituent of cytoskeleton spindle pole body ->
cytoplasm STB1, SWI4
|YOL028C| YAP7 positive regulation of transcription from Pol II promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription RNA polymerase II transcription factor activity ->
RNA polymerase II transcription factor activity nucleus ->
nucleus NRG1
YLR308W CDA2 spore wall assembly (sensu Saccharomyces) ->
sporulation chitin deacetylase activity ->
chitin deacetylase activity chitosan layer of spore wall ->
cell wall REB1, SUM1
|YMR204C| NO SYMBOL STE12
YMR001C CDC5 DNA dependent DNA replication, protein amino acid phosphorylation ->
phosphorus metabolism, cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism protein serine/threonine kinase activity ->
protein serine/threonine kinase activity nucleus, spindle pole, bud neck ->
nucleus, cytoplasm, site of polarized growth (sensu Fungi) NDD1, REB1, SWI6
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.44) structural constituent of cell wall (0.14) cytoplasm (0.43) STE12 (0.27)
Score: 0.36 0.00 0.33 0.182
P-value: 4.087E-01 (microtubule cytoskeleton organization and biogenesis) 1.148E+00 (structural molecule activity) 1.882E-01 (spindle pole) 5.856E-02 (STE12)

ndt80(MSE)(1) AND SFF'(1) AND MCM1'(1) => SimExpr(YGL116W) OR SimExpr(other) : 11 5

EXPR: (0.250) ndt80(MSE) (P < 0.575) SFF' (P < 0.000) MCM1' (P < 0.000)

ORF SYMBOL P F C TF
YKL104C GFA1 cell wall chitin biosynthesis ->
cell organization and biogenesis, biosynthesis, polysaccharide metabolism, carbohydrate metabolism glucosamine-fructose-6-phosphate aminotransferase (isomerizing) activity ->
glucosamine-fructose-6-phosphate aminotransferase (isomerizing) activity REB1
YNR034W SOL1 tRNA processing ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism YFL044C
YKL096W CWP1 cell wall organization and biogenesis ->
cell organization and biogenesis structural molecule activity ->
structural molecule activity cell wall (sensu Fungi) ->
cell wall RLM1, SMP1, STE12, SWI4
YFR023W PES4 DNA dependent DNA replication ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DIG1, FKH1, FKH2, GLN3, HAP3, MCM1, MSN2, RIM101, RLM1, RTG3, STE12, SUM1, THI2, YAP1
|YMR111C| NO SYMBOL GRF10(Pho2)
|YPL109C| NO SYMBOL
YGL116W CDC20 mitotic spindle elongation, ubiquitin-dependent protein catabolism, mitotic metaphase/anaphase transition, mitotic chromosome segregation, cyclin catabolism ->
cell organization and biogenesis, catabolism, cell proliferation, cell cycle, protein metabolism enzyme activator activity ->
enzyme activator activity anaphase-promoting complex ->
nucleus, ubiquitin ligase complex DIG1, FKH2, INO2, INO4, IXR1, MCM1, NDD1
YJR007W SUI2 translational initiation ->
biosynthesis, protein metabolism translation initiation factor activity ->
translation initiation factor activity ribosome, cytoplasm ->
cytoplasm, ribonucleoprotein complex GLN3, HAP3, HIR1, RCS1
YGL230C NO SYMBOL HIR1, MATa1
|YOR388C| FDH1 formate catabolism, NADH regeneration ->
catabolism, coenzymes and prosthetic group metabolism, one-carbon compound metabolism, vitamin metabolism, organic acid metabolism formate dehydrogenase activity ->
formate dehydrogenase activity cytosol ->
cytoplasm MCM1, YJL206C
YPL255W BBP1 microtubule nucleation ->
cell organization and biogenesis structural molecule activity ->
structural molecule activity spindle pole body ->
cytoplasm STB1, SWI4
YGL170C SPO74 sporulation (sensu Saccharomyces) ->
sporulation structural molecule activity ->
structural molecule activity spindle pole body ->
cytoplasm MOT3, MSS11, SUM1
|YOL028C| YAP7 positive regulation of transcription from Pol II promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription RNA polymerase II transcription factor activity ->
RNA polymerase II transcription factor activity nucleus ->
nucleus NRG1
YLR308W CDA2 spore wall assembly (sensu Saccharomyces) ->
sporulation chitin deacetylase activity ->
chitin deacetylase activity chitosan layer of spore wall ->
cell wall REB1, SUM1
|YMR204C| NO SYMBOL STE12
YMR001C CDC5 DNA dependent DNA replication, protein amino acid phosphorylation ->
phosphorus metabolism, cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism protein serine/threonine kinase activity ->
protein serine/threonine kinase activity nucleus, spindle pole, bud neck ->
nucleus, cytoplasm, site of polarized growth (sensu Fungi) NDD1, REB1, SWI6
Main: cell organization and biogenesis (0.33) structural molecule activity (0.30) cytoplasm (0.56) REB1 SUM1 STE12 MCM1 (0.20)
Score: 0.29 0.07 0.39 0.152
P-value: 1.143E+00 (microtubule cytoskeleton organization and biogenesis) 9.729E-01 (structural molecule activity) 3.374E-02 (spindle pole) 9.953E-02 (SUM1)

MCM1(1) AND ndt80(MSE)(1) => SimExpr(YGL116W) : 5

EXPR: (0.134) ndt80(MSE) (P < 0.050) MCM1 (P < 0.000)

ndt80(MSE)(1) AND SFF'(1) AND SWI5(1) AND MCM1'(1) => SimExpr(YGL116W) : 5

EXPR: (0.115) ndt80(MSE) (P < 0.020) SFF' (P < 0.000) SWI5 (P < 0.000) MCM1' (P < 0.000)

HSE(1) AND MCM1'(1) AND SCB(1) => SimExpr(YLL010C) OR SimExpr(other) : 5 2

EXPR: (0.291) HSE (P < 0.007) MCM1' (P < 0.001) SCB (P < 0.004)

ORF SYMBOL P F C TF
|YHL008C| NO SYMBOL RFX1, RTG1, YJL206C
YDR116C MRPL1 protein biosynthesis, meiosis, aerobic respiration ->
protein biosynthesis, M phase, cellular respiration structural constituent of ribosome ->
structural constituent of ribosome mitochondrial large ribosomal subunit ->
cytoplasm, ribonucleoprotein complex CHA4, GRF10(Pho2)
|YGR142W| BTN2 regulation of pH, intracellular protein transport ->
cation homeostasis, intracellular protein transport cytosol ->
cytoplasm HSF1, MSN4
YLL010C PSR1 response to stress ->
response to stress protein phosphatase activity ->
protein phosphatase activity plasma membrane ->
plasma membrane CBF1
YKL185W ASH1 regulation of transcription\, mating-type specific, pseudohyphal growth ->
mating-type determination, growth pattern, regulation of transcription, transcription\, DNA-dependent specific transcriptional repressor activity ->
specific transcriptional repressor activity nucleus ->
nucleus SMP1, SWI5
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent RNA binding ->
RNA binding nucleolus ->
nucleus
YOR086C NO SYMBOL ABF1, STE12
Main: transcription\, DNA-dependent (0.40) RNA binding (0.25) cytoplasm (0.40) ABF1 (0.17)
Score: 0.10 0.00 0.20 0.000
P-value: 1.864E+00 (transcription\, DNA-dependent) 2.000E+00 4.535E+00 (nucleus) 9.217E-01 (CHA4)

ALPHA1'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YGR280C) OR SimExpr(other) : 32 15

EXPR: (0.240) ALPHA1' (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.001)

ALPHA1'(1) AND SWI5(1) AND PAC(1) AND SCB(1) => SimExpr(YGR280C) OR SimExpr(other) : 5 2

EXPR: (0.220) ALPHA1' (P < 0.000) SWI5 (P < 0.000) PAC (P < 0.059) SCB (P < 0.000)

ORF SYMBOL P F C TF
|YKL120W| OAC1 oxaloacetate transport, sulfate transport ->
transport oxaloacetate carrier activity, sulfate porter activity ->
electrochemical potential-driven transporter activity, anion transporter activity, organic cation transporter activity, carboxylic acid transporter activity mitochondrial inner membrane ->
cytoplasm, inner membrane LEU3, MTH1
YLL010C PSR1 response to stress ->
response to stress protein phosphatase activity ->
hydrolase activity\, acting on ester bonds plasma membrane ->
plasma membrane CBF1
YJL109C UTP10 processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding nucleolus ->
nucleus
|YIL066C| RNR3 DNA replication ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ribonucleoside-diphosphate reductase activity ->
oxidoreductase activity\, acting on CH2 groups cytoplasm ->
cytoplasm RFX1, STB1
YOR294W RRS1 ribosome biogenesis, rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism nucleus ->
nucleus STB1
YOR310C NOP58 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex ABF1, SWI6
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.71) RNA binding (0.40) nucleus (0.57) STB1 (0.40)
Score: 0.48 0.10 0.33 0.100
P-value: 3.816E-04 (rRNA processing) 5.233E-01 (RNA binding) 8.698E-03 (small nucleolar ribonucleoprotein complex) 2.235E-02 (STB1)

ALPHA1'(1) AND mRRPE(1) AND SWI5(1) AND PAC(1) => SimExpr(YGR280C) OR SimExpr(other) : 7 3

EXPR: (0.248) ALPHA1' (P < 0.000) mRRPE (P < 0.026) SWI5 (P < 0.000) PAC (P < 0.100)

SFF(1) AND ndt80(MSE)(1) => SimExpr(YLR049C) OR SimExpr(other) : 25 12

EXPR: (0.239) SFF (P < 0.000) ndt80(MSE) (P < 0.139)

ORF SYMBOL P F C TF
|YLR154C| RNH203 RLM1
YDR042C NO SYMBOL ARG80, ARG81, AZF1, CIN5, CUP9, DIG1, FZF1, GCR2, HAL9, HAP2, HAP4, HAP5, HIR2, HMS1, IXR1, LEU3, MBP1, MCM1, MET31, NRG1, PDR1, RLM1, RME1, ROX1, RTG1, RTG3, SRD1, STE12, SUM1, YAP6, ZAP1
|YNL196C| NO SYMBOL
YDR522C SPS2 sporulation (sensu Saccharomyces) ->
sporulation cell wall (sensu Fungi) ->
cell wall ARG81, HAL9, HAP5, HIR2, HMS1, LEU3, MET31, RTG3, SUM1
YFL040W NO SYMBOL SUM1
YNR034W SOL1 tRNA processing ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism YFL044C
YDL028C MPS1 mitotic spindle checkpoint, spindle pole body duplication (sensu Saccharomyces) ->
cell organization and biogenesis, cell cycle protein threonine/tyrosine kinase activity ->
protein kinase activity spindle pole body, condensed nuclear chromosome kinetochore ->
cytoplasm, chromosome\, pericentric region, condensed chromosome, chromosome, nucleus SUM1
YKL096W CWP1 cell wall organization and biogenesis ->
cell organization and biogenesis structural constituent of cell wall ->
structural molecule activity cell wall (sensu Fungi) ->
cell wall RLM1, SMP1, STE12, SWI4
YNL034W NO SYMBOL MAC1, MET4, NDD1, RME1
YFR023W PES4 DNA dependent DNA replication ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DIG1, FKH1, FKH2, GLN3, HAP3, MCM1, MSN2, RIM101, RLM1, RTG3, STE12, SUM1, THI2, YAP1
YHR184W SSP1 spore wall assembly (sensu Saccharomyces), protein complex assembly ->
protein metabolism, sporulation prospore membrane ->
prospore SUM1
YGR059W SPR3 cellular morphogenesis, cell wall organization and biogenesis, spore wall assembly (sensu Saccharomyces), cellular morphogenesis during conjugation with cellular fusion ->
cell organization and biogenesis, conjugation with cellular fusion, perception of external stimulus, sporulation, sensory perception, response to abiotic stimulus structural constituent of cytoskeleton ->
structural molecule activity septin ring (sensu Saccharomyces), spore wall (sensu Fungi), prospore membrane ->
site of polarized growth (sensu Fungi), cell wall, prospore, cell cortex, cytoskeleton ABF1, RFX1, SUM1
|YOR191W| RIS1 chromatin assembly/disassembly, mating-type switching/recombination ->
cell organization and biogenesis, mating-type determination, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DNA dependent ATPase activity ->
ATP binding, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides nucleus ->
nucleus
YOL132W GAS4 cell wall (sensu Fungi) ->
cell wall
YGL116W CDC20 mitotic spindle elongation, ubiquitin-dependent protein catabolism, mitotic metaphase/anaphase transition, mitotic chromosome segregation, cyclin catabolism ->
cell organization and biogenesis, catabolism, cell proliferation, cell cycle, protein metabolism enzyme activator activity ->
enzyme activator activity anaphase-promoting complex ->
nucleus, ubiquitin ligase complex DIG1, FKH2, INO2, INO4, IXR1, MCM1, NDD1
|YJR007W| SUI2 translational initiation ->
biosynthesis, protein metabolism translation initiation factor activity ->
translation initiation factor activity ribosome, cytoplasm ->
cytoplasm, ribonucleoprotein complex GLN3, HAP3, HIR1, RCS1
YLR227C ADY4 sporulation ->
sporulation structural molecule activity ->
structural molecule activity spindle pole body ->
cytoplasm AZF1
YMR252C NO SYMBOL SKN7
|YML050W| NO SYMBOL FKH2, MCM1, NDD1, SKN7
YDR281C PHM6 PHO4, SUM1
YGL230C NO SYMBOL HIR1, MATa1
|YHL043W| ECM34 cell wall organization and biogenesis ->
cell organization and biogenesis
YBR115C LYS2 lysine biosynthesis\, aminoadipic pathway ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis aminoadipate-semialdehyde dehydrogenase activity ->
aminoadipate-semialdehyde dehydrogenase activity cytoplasm ->
cytoplasm DAL81, GCN4
YPL255W BBP1 microtubule nucleation ->
cell organization and biogenesis structural constituent of cytoskeleton ->
structural molecule activity spindle pole body ->
cytoplasm STB1, SWI4
YLR049C NO SYMBOL MBP1, SWI5
YBR250W NO SYMBOL CBF1, GCN4
|YDR438W| NO SYMBOL CBF1
YDR218C SPR28 cellular morphogenesis, cell wall organization and biogenesis ->
cell organization and biogenesis structural constituent of cytoskeleton ->
structural molecule activity septin ring (sensu Saccharomyces) ->
site of polarized growth (sensu Fungi), cell cortex, cytoskeleton YAP6
|YGL121C| GPG1 signal transduction ->
signal transduction signal transducer activity ->
signal transducer activity CHA4
|YOL028C| YAP7 positive regulation of transcription from Pol II promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription RNA polymerase II transcription factor activity ->
RNA polymerase II transcription factor activity nucleus ->
nucleus NRG1
YOR214C NO SYMBOL BAS1
|YGL046W| NO SYMBOL
|YMR280C| CAT8 gluconeogenesis, positive regulation of transcription from Pol II promoter ->
alcohol metabolism, monosaccharide metabolism, carbohydrate metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, biosynthesis, energy pathways specific RNA polymerase II transcription factor activity ->
RNA polymerase II transcription factor activity nucleus ->
nucleus ABF1, REB1
YLR308W CDA2 spore wall assembly (sensu Saccharomyces) ->
sporulation chitin deacetylase activity ->
chitin deacetylase activity chitosan layer of spore wall ->
cell wall REB1, SUM1
|YMR204C| NO SYMBOL STE12
YMR001C CDC5 DNA dependent DNA replication, protein amino acid phosphorylation ->
phosphorus metabolism, cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism protein serine/threonine kinase activity ->
protein kinase activity nucleus, spindle pole, bud neck ->
nucleus, cytoplasm, site of polarized growth (sensu Fungi) NDD1, REB1, SWI6
YFR012W NO SYMBOL DAL81
Main: cell organization and biogenesis (0.40) structural molecule activity (0.33) cytoplasm (0.35) SUM1 (0.28)
Score: 0.33 0.11 0.32 0.141
P-value: 9.263E-02 (sporulation) 1.851E-01 (structural constituent of cytoskeleton) 5.972E-02 (cell wall (sensu Fungi)) 8.984E-07 (SUM1)

ndt80(MSE)(1) AND CCA(1) => SimExpr(YLR049C) OR SimExpr(other) : 5 1

EXPR: (0.148) ndt80(MSE) (P < 0.008) CCA (P < 0.000)

ORF SYMBOL P F C TF
YPR122W AXL1 axial budding, bud site selection, conjugation with cellular fusion, peptide pheromone maturation ->
budding, conjugation with cellular fusion, protein modification, cytokinesis, cytoplasm organization and biogenesis metalloendopeptidase activity ->
metalloendopeptidase activity integral to membrane, bud neck, shmoo tip ->
integral to membrane, bud neck, shmoo tip CIN5
YMR252C NO SYMBOL SKN7
YGL230C NO SYMBOL HIR1, MATa1
YLR049C NO SYMBOL MBP1, SWI5
|YIL151C| NO SYMBOL RGT1, THI2
YOR339C UBC11 protein polyubiquitination, protein monoubiquitination ->
macromolecule catabolism, protein modification, protein metabolism ubiquitin conjugating enzyme activity ->
ubiquitin conjugating enzyme activity cytoplasm ->
cytoplasm HAP2, IXR1
Main: protein modification (1.00) metalloendopeptidase activity (0.50) cytoplasm (0.50) SWI5 (0.17)
Score: 1.00 0.00 0.00 0.000
P-value: 5.515E-01 (protein modification) 2.737E+00 (enzyme activity) 3.000E+00 (cell) 3.357E-01 (THI2)

LYS14(1) AND ndt80(MSE)(1) => SimExpr(YLR049C) OR SimExpr(other) : 6 2

EXPR: (0.249) LYS14 (P < 0.001) ndt80(MSE) (P < 0.419)

ORF SYMBOL P F C TF
|YGR060W| ERG25 ergosterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism C-4 methyl sterol oxidase activity ->
C-4 methyl sterol oxidase activity endoplasmic reticulum membrane, plasma membrane ->
cytoplasm, plasma membrane, endomembrane system HSF1, MAL13, MET4, NDD1, SWI5
YHR124W NDT80 meiosis, transcription ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism transcription factor activity ->
transcription factor activity nuclear chromosome ->
chromosome, nucleus SUM1
YDR317W NO SYMBOL HAL9, RLM1
YBR115C LYS2 lysine biosynthesis\, aminoadipic pathway ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis aminoadipate-semialdehyde dehydrogenase activity ->
aminoadipate-semialdehyde dehydrogenase activity cytoplasm ->
cytoplasm DAL81, GCN4
YLR049C NO SYMBOL MBP1, SWI5
YDR218C SPR28 cellular morphogenesis, cell wall organization and biogenesis ->
cell organization and biogenesis structural constituent of cytoskeleton ->
structural constituent of cytoskeleton septin ring (sensu Saccharomyces) ->
site of polarized growth (sensu Fungi), cell cortex, cytoskeleton YAP6
|YGL046W| NO SYMBOL
YLR308W CDA2 spore wall assembly (sensu Saccharomyces) ->
sporulation chitin deacetylase activity ->
chitin deacetylase activity chitosan layer of spore wall ->
cell wall REB1, SUM1
Main: biosynthesis (0.40) transcription factor activity (0.20) cytoplasm (0.40) SWI5 SUM1 (0.29)
Score: 0.10 0.00 0.10 0.095
P-value: 3.657E+00 (biosynthesis) 5.241E-01 (oxidoreductase activity) 4.615E+00 (cytoplasm) 1.215E-01 (SUM1)

ndt80(MSE)(1) AND SWI5(1) => SimExpr(YKL104C) OR SimExpr(other) : 16 7

ALPHA1'(1) AND ndt80(MSE)(1) AND SWI5(1) => SimExpr(YKL104C) OR SimExpr(other) : 10 4

EXPR: (0.229) ALPHA1' (P < 0.000) ndt80(MSE) (P < 0.285) SWI5 (P < 0.000)

ORF SYMBOL P F C TF
|YLR154C| RNH203 RLM1
YKL104C GFA1 cell wall chitin biosynthesis ->
cell organization and biogenesis, biosynthesis, polysaccharide metabolism, carbohydrate metabolism glucosamine-fructose-6-phosphate aminotransferase (isomerizing) activity ->
glucosamine-fructose-6-phosphate aminotransferase (isomerizing) activity REB1
YPR122W AXL1 axial budding, bud site selection, conjugation with cellular fusion, peptide pheromone maturation ->
asexual reproduction, conjugation, protein metabolism, cell proliferation, cell organization and biogenesis, sexual reproduction metalloendopeptidase activity ->
metalloendopeptidase activity integral to membrane, bud neck, shmoo tip ->
integral to membrane, site of polarized growth (sensu Fungi) CIN5
YDR042C NO SYMBOL ARG80, ARG81, AZF1, CIN5, CUP9, DIG1, FZF1, GCR2, HAL9, HAP2, HAP4, HAP5, HIR2, HMS1, IXR1, LEU3, MBP1, MCM1, MET31, NRG1, PDR1, RLM1, RME1, ROX1, RTG1, RTG3, SRD1, STE12, SUM1, YAP6, ZAP1
YNL196C NO SYMBOL
YHR124W NDT80 meiosis, transcription ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism transcription factor activity ->
transcription factor activity nuclear chromosome ->
chromosome, nucleus SUM1
YNL034W NO SYMBOL MAC1, MET4, NDD1, RME1
|YBR159W| NO SYMBOL ACE2, ARG81, GCR2, HIR2, LEU3, MOT3, PDR1, PHD1, SKN7, USV1
YOL132W GAS4 cell wall (sensu Fungi) ->
cell wall
YGL116W CDC20 mitotic spindle elongation, ubiquitin-dependent protein catabolism, mitotic metaphase/anaphase transition, mitotic chromosome segregation, cyclin catabolism ->
cell organization and biogenesis, catabolism, cell proliferation, cell cycle, protein metabolism enzyme activator activity ->
enzyme activator activity anaphase-promoting complex ->
nucleus, ubiquitin ligase complex DIG1, FKH2, INO2, INO4, IXR1, MCM1, NDD1
|YHL043W| ECM34 cell wall organization and biogenesis ->
cell organization and biogenesis
YFR032C NO SYMBOL PUT3, SUM1
YOR214C NO SYMBOL BAS1
|YMR280C| CAT8 gluconeogenesis, positive regulation of transcription from Pol II promoter ->
alcohol metabolism, monosaccharide metabolism, carbohydrate metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, biosynthesis, energy pathways specific RNA polymerase II transcription factor activity ->
specific RNA polymerase II transcription factor activity nucleus ->
nucleus ABF1, REB1
Main: cell organization and biogenesis (0.67) metalloendopeptidase activity (0.20) nucleus (0.60) SUM1 (0.27)
Score: 0.67 0.00 0.30 0.182
P-value: 6.517E-01 (carbohydrate biosynthesis) 1.375E+00 (transcription regulator activity) 4.547E+00 (nucleus) 9.556E-02 (SUM1)

ndt80(MSE)(1) AND mRRPE(1) => SimExpr(YJR007W) OR SimExpr(other) : 6 1

EXPR: (0.196) ndt80(MSE) (P < 0.008) mRRPE (P < 0.000)

ORF SYMBOL P F C TF
YFR023W PES4 DNA dependent DNA replication ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DIG1, FKH1, FKH2, GLN3, HAP3, MCM1, MSN2, RIM101, RLM1, RTG3, STE12, SUM1, THI2, YAP1
YHR184W SSP1 spore wall assembly (sensu Saccharomyces), protein complex assembly ->
protein metabolism, sporulation prospore membrane ->
prospore SUM1
|YGL253W| HXK2 fructose metabolism ->
alcohol metabolism, carbohydrate metabolism hexokinase activity ->
hexokinase activity nucleus, cytosol ->
nucleus, cytoplasm ABF1, CIN5, HSF1, SWI4
YJR007W SUI2 translational initiation ->
biosynthesis, protein metabolism translation initiation factor activity ->
translation initiation factor activity ribosome, cytoplasm ->
cytoplasm, ribonucleoprotein complex GLN3, HAP3, HIR1, RCS1
YOL091W SPO21 spore wall assembly (sensu Saccharomyces), meiosis ->
cell proliferation, sporulation structural molecule activity ->
structural molecule activity spindle pole body ->
cytoplasm HAP5, SUM1
YOR338W NO SYMBOL RAP1
YOR339C UBC11 protein polyubiquitination, protein monoubiquitination ->
catabolism, protein metabolism ubiquitin conjugating enzyme activity ->
ubiquitin conjugating enzyme activity cytoplasm ->
cytoplasm HAP2, IXR1
Main: protein metabolism (0.50) ubiquitin conjugating enzyme activity (0.25) cytoplasm (0.80) SUM1 (0.43)
Score: 0.33 0.00 0.60 0.190
P-value: 2.092E-02 (spore wall assembly (sensu Saccharomyces)) 2.857E+00 (enzyme activity) 3.171E+00 (cytoplasm) 5.273E-03 (SUM1)

CSRE(1) AND ndt80(MSE)(1) => SimExpr(YKL096W) OR SimExpr(other) : 6 1

EXPR: (0.190) ndt80(MSE) (P < 0.031) CSRE (P < 0.000)

ORF SYMBOL P F C TF
YHR124W NDT80 meiosis, transcription ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism transcription factor activity ->
transcription factor activity nuclear chromosome ->
chromosome, nucleus SUM1
YKL096W CWP1 cell wall organization and biogenesis ->
cell organization and biogenesis structural constituent of cell wall ->
structural constituent of cell wall cell wall (sensu Fungi) ->
cell wall RLM1, SMP1, STE12, SWI4
|YGL253W| HXK2 fructose metabolism ->
alcohol metabolism, carbohydrate metabolism hexokinase activity ->
hexokinase activity nucleus, cytosol ->
nucleus, cytoplasm ABF1, CIN5, HSF1, SWI4
YML050W NO SYMBOL FKH2, MCM1, NDD1, SKN7
YPL255W BBP1 microtubule nucleation ->
cell organization and biogenesis structural constituent of cytoskeleton ->
structural constituent of cytoskeleton spindle pole body ->
cytoplasm STB1, SWI4
YLR049C NO SYMBOL MBP1, SWI5
YBR069C TAT1 amino acid transport ->
transport amino acid transporter activity ->
amino acid transporter activity plasma membrane ->
plasma membrane CIN5, DAL81, PHD1, SWI4
Main: cell organization and biogenesis (0.40) structural constituent of cell wall (0.20) cytoplasm (0.40) SWI4 (0.57)
Score: 0.10 0.00 0.20 0.286
P-value: 4.052E+00 (cell growth and/or maintenance) 4.212E-01 (structural molecule activity) 4.535E+00 (nucleus) 1.369E-03 (SWI4)

mRRPE(1) AND PAC(1) => SimExpr(YOR310C) OR SimExpr(other) : 59 24

EXPR: (0.227) mRRPE (P < 0.000) PAC (P < 0.000)

mRRPE(1) AND PAC(1) AND MCM1'(1) => SimExpr(YOR310C) OR SimExpr(other) : 12 5

EXPR: (0.223) mRRPE (P < 0.000) PAC (P < 0.012) MCM1' (P < 0.000)

mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YOR310C) OR SimExpr(other) : 15 6

EXPR: (0.216) mRRPE (P < 0.000) PAC (P < 0.002) SCB (P < 0.000)

ALPHA1'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YOR310C) OR SimExpr(other) : 33 14

SFF'(1) AND mRRPE(1) AND PAC(1) AND MCM1'(1) => SimExpr(YOR310C) OR SimExpr(other) : 6 2

EXPR: (0.247) SFF' (P < 0.000) mRRPE (P < 0.034) PAC (P < 0.152) MCM1' (P < 0.000)

ORF SYMBOL P F C TF
|YML125C| NO SYMBOL MAL13, MSN4, NDD1, RME1, SWI5
|YDR279W| RNH202 GCR2, MBP1, RIM101, RLM1, SWI6, THI2
YIL122W POG1 re-entry into mitotic cell cycle after pheromone arrest ->
re-entry into mitotic cell cycle, conjugation with cellular fusion, response to pheromone specific RNA polymerase II transcription factor activity ->
specific RNA polymerase II transcription factor activity nucleus ->
nucleus ASH1, CIN5, NRG1, RLM1, SMP1, YAP6
YOR095C RKI1 pentose-phosphate shunt ->
glucose catabolism, main pathways of carbohydrate metabolism, nicotinamide metabolism ribose-5-phosphate isomerase activity ->
ribose-5-phosphate isomerase activity FHL1, FKH2, RAP1
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
rRNA processing, snRNA processing RNA binding ->
RNA binding nucleolus ->
nucleus
YOR310C NOP58 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
rRNA modification, rRNA processing small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex ABF1, SWI6
YGL029W CGR1 ribosome biogenesis, rRNA processing ->
ribosome biogenesis, rRNA processing nucleolus ->
nucleus
YCR016W NO SYMBOL
Main: rRNA processing (0.60) RNA binding (0.33) nucleus (1.00) RLM1 SWI6 (0.40)
Score: 0.30 0.00 1.00 0.200
P-value: 2.047E-02 (rRNA processing) 2.000E+00 1.578E-02 (nucleolus) 2.443E-01 (RLM1)

ALPHA1'(1) AND mRRPE(1) AND PAC(1) AND MCM1'(1) => SimExpr(YOR310C) OR SimExpr(other) : 7 3

EXPR: (0.212) ALPHA1' (P < 0.000) mRRPE (P < 0.001) PAC (P < 0.017) MCM1' (P < 0.000)

SFF'(1) AND mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YOR310C) OR SimExpr(other) : 8 4

EXPR: (0.242) SFF' (P < 0.000) mRRPE (P < 0.007) PAC (P < 0.099) SCB (P < 0.000)

ALPHA1'(1) AND mRRPE(1) AND SWI5(1) AND PAC(1) => SimExpr(YOR310C) OR SimExpr(other) : 7 3

CSRE(1) AND ndt80(MSE)(1) => SimExpr(YHR124W) OR SimExpr(other) : 6 1

CSRE(1) AND ndt80(MSE)(1) => SimExpr(YPL255W) OR SimExpr(other) : 5 2

CSRE(1) AND ndt80(MSE)(1) => SimExpr(YML050W) OR SimExpr(other) : 5 2

MCM1(1) AND mRRPE(1) AND PAC(1) => SimExpr(YDR184C) OR SimExpr(other) : 5 1

EXPR: (0.205) mRRPE (P < 0.000) PAC (P < 0.007) MCM1 (P < 0.000)

ORF SYMBOL P F C TF
YBR267W NO SYMBOL
|YDR279W| RNH202 GCR2, MBP1, RIM101, RLM1, SWI6, THI2
YIL122W POG1 re-entry into mitotic cell cycle after pheromone arrest ->
re-entry into mitotic cell cycle, conjugation with cellular fusion, response to pheromone specific RNA polymerase II transcription factor activity ->
specific RNA polymerase II transcription factor activity nucleus ->
nucleus ASH1, CIN5, NRG1, RLM1, SMP1, YAP6
YDR184C ATC1 response to stress, polar budding ->
response to stress, polar budding nucleus ->
nucleus ARO80, GLN3, SIP4, SKO1
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
rRNA processing, snRNA processing RNA binding ->
RNA binding nucleolus ->
nucleus
YGL029W CGR1 ribosome biogenesis, rRNA processing ->
ribosome biogenesis, rRNA processing nucleolus ->
nucleus
Main: rRNA processing (0.50) RNA binding (0.50) nucleus (1.00) RLM1 (0.67)
Score: 0.17 0.00 1.00 0.333
P-value: 2.148E-01 (rRNA processing) 2.000E+00 1.182E-01 (nucleolus) 1.010E-01 (RLM1)

ALPHA1'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YGL029W) OR SimExpr(other) : 33 14

ALPHA1'(1) AND mRRPE(1) AND PAC(1) AND MCM1'(1) => SimExpr(YGL029W) OR SimExpr(other) : 8 2

ALPHA1(1) AND mRRPE(1) AND PAC(1) => SimExpr(YGL029W) OR SimExpr(other) : 18 6

EXPR: (0.225) mRRPE (P < 0.000) PAC (P < 0.007) ALPHA1 (P < 0.000)

ALPHA1(1) AND SFF(1) AND mRRPE(1) AND PAC(1) => SimExpr(YGL029W) OR SimExpr(other) : 9 3

EXPR: (0.230) SFF (P < 0.000) mRRPE (P < 0.003) PAC (P < 0.058) ALPHA1 (P < 0.000)

ORF SYMBOL P F C TF
YOL022C NO SYMBOL MAC1, MOT3, RTS2
YCR072C NO SYMBOL YFL044C
YMR290C HAS1 nucleolus, nuclear membrane ->
nucleus, endomembrane system RAP1
YJL069C UTP18 ABF1
|YJL033W| HCA4 35S primary transcript processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus HIR2, USV1
YJL109C UTP10 processing of 20S pre-rRNA ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
YMR259C NO SYMBOL ARG80, GCR2, GTS1, HIR1, SRD1
|YPR183W| DPM1 N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
phospholipid biosynthesis, protein biosynthesis, glycerophospholipid metabolism, protein modification, glycoprotein metabolism, lipoprotein metabolism transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
cytoplasm, endomembrane system SWI5
YLR249W YEF3 translational elongation ->
protein biosynthesis translation elongation factor activity ->
translation factor activity\, nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex INO2, INO4
|YHR169W| DBP8 35S primary transcript processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus
YGL029W CGR1 ribosome biogenesis, rRNA processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent nucleolus ->
nucleus
YOR381W FRE3 iron-siderochrome transport, iron ion homeostasis ->
iron-siderochrome transport, cation homeostasis ferric-chelate reductase activity ->
oxidoreductase activity\, oxidizing metal ions plasma membrane, integral to membrane ->
plasma membrane, integral to membrane CIN5, PDR1, YAP6
Main: RNA processing (0.57) RNA binding (0.50) nucleus (0.62) GCR2 (0.11)
Score: 0.33 0.20 0.46 0.000
P-value: 5.611E-03 (rRNA processing) 2.860E-02 (ATP dependent RNA helicase activity) 4.568E-04 (nucleolus) 1.000E+00

ALPHA1(1) AND SFF'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YGL029W) OR SimExpr(other) : 10 4

EXPR: (0.232) SFF' (P < 0.000) mRRPE (P < 0.001) PAC (P < 0.039) ALPHA1 (P < 0.000)

ORF SYMBOL P F C TF
YOL022C NO SYMBOL MAC1, MOT3, RTS2
YCR072C NO SYMBOL YFL044C
YMR290C HAS1 nucleolus, nuclear membrane ->
nucleus, endomembrane system RAP1
|YKL056C| NO SYMBOL
YJL069C UTP18 ABF1
YOR095C RKI1 pentose-phosphate shunt ->
monosaccharide catabolism, main pathways of carbohydrate metabolism, oxidoreduction coenzyme metabolism, hexose metabolism, water-soluble vitamin metabolism ribose-5-phosphate isomerase activity ->
intramolecular isomerase activity FHL1, FKH2, RAP1
|YJL033W| HCA4 35S primary transcript processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus HIR2, USV1
YNL075W IMP4 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
RNA processing, ribosome biogenesis and assembly, rRNA metabolism, transcription\, DNA-dependent rRNA primary transcript binding ->
RNA binding small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex USV1
YJL109C UTP10 processing of 20S pre-rRNA ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
|YPR183W| DPM1 N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
phospholipid biosynthesis, protein biosynthesis, glycerophospholipid metabolism, protein modification, glycoprotein metabolism, lipoprotein metabolism transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
cytoplasm, endomembrane system SWI5
YLR249W YEF3 translational elongation ->
protein biosynthesis translation elongation factor activity ->
translation factor activity\, nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex INO2, INO4
|YHR169W| DBP8 35S primary transcript processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus
YGL029W CGR1 ribosome biogenesis, rRNA processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent nucleolus ->
nucleus
YOR381W FRE3 iron-siderochrome transport, iron ion homeostasis ->
iron-siderochrome transport, cation homeostasis ferric-chelate reductase activity ->
oxidoreductase activity\, oxidizing metal ions plasma membrane, integral to membrane ->
plasma membrane, integral to membrane CIN5, PDR1, YAP6
Main: RNA processing (0.56) RNA binding (0.50) nucleus (0.67) USV1 RAP1 (0.20)
Score: 0.31 0.21 0.53 0.044
P-value: 6.168E-04 (rRNA processing) 3.923E-02 (ATP dependent RNA helicase activity) 6.528E-05 (nucleolus) 1.874E-01 (USV1)

SFF(1) AND SWI5(1) AND AFT1(1) AND SCB(1) => SimExpr(YMR253C) OR SimExpr(other) : 5 1

EXPR: (0.200) SFF (P < 0.001) SWI5 (P < 0.000) AFT1 (P < 0.000) SCB (P < 0.001)

ORF SYMBOL P F C TF
YHR085W IPI1 rRNA processing ->
cytoplasm organization and biogenesis, RNA metabolism, transcription FZF1
YMR253C NO SYMBOL MCM1
YLR229C CDC42 exocytosis, apical bud growth, isotropic bud growth, pseudohyphal growth, invasive growth, Rho protein signal transduction, signal transduction during conjugation with cellular fusion, establishment of cell polarity (sensu Saccharomyces) ->
secretory pathway, budding, growth pattern, cellular morphogenesis, intracellular signaling cascade, cell surface receptor linked signal transduction, conjugation with cellular fusion, cytoplasm organization and biogenesis, perception of abiotic stimulus, sensory perception, vesicle-mediated transport Rho small monomeric GTPase activity, signal transducer activity ->
Rho small monomeric GTPase activity, signal transducer activity soluble fraction, plasma membrane, bud tip, bud neck, shmoo tip ->
soluble fraction, plasma membrane, bud tip, bud neck, shmoo tip ABF1, FZF1, INO2, RTS2
YOL132W GAS4 cell wall (sensu Fungi) ->
cell wall (sensu Fungi)
YDR297W SUR2 sphingolipid metabolism, sphingolipid biosynthesis ->
membrane lipid metabolism, lipid biosynthesis sphingosine hydroxylase activity ->
sphingosine hydroxylase activity endoplasmic reticulum ->
endoplasmic reticulum CBF1, MTH1
|YPR185W| APG13 protein-vacuolar targeting, autophagy ->
cytoplasm organization and biogenesis, autophagy, intracellular transport, protein metabolism, protein transport protein binding ->
protein binding extrinsic to membrane ->
extrinsic to membrane MET4, SWI6
Main: cytoplasm organization and biogenesis (0.75) protein binding (0.33) endoplasmic reticulum (0.25) FZF1 (0.40)
Score: 0.50 0.00 0.00 0.100
P-value: 7.326E-01 (cytoplasm organization and biogenesis) 2.356E+00 (binding) 1.742E+00 (membrane) 4.289E-02 (FZF1)

LYS14(1) AND mRRPE(1) AND PAC(1) => SimExpr(YNL110C) OR SimExpr(other) : 6 2

EXPR: (0.162) LYS14 (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.005)

ORF SYMBOL P F C TF
|YHR128W| FUR1 pyrimidine salvage ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism uracil phosphoribosyltransferase activity ->
transferase activity\, transferring glycosyl groups CIN5
YMR290C HAS1 nucleolus, nuclear membrane ->
nucleolus, nuclear membrane RAP1
YML093W UTP14 processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleolus, ribonucleoprotein complex
YNL110C NOP15 ribosomal large subunit biogenesis ->
cell organization and biogenesis nucleus, nucleolus ->
nucleus, nucleolus
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding nucleolus ->
nucleolus
|YMR259C| NO SYMBOL ARG80, GCR2, GTS1, HIR1, SRD1
YJR070C NO SYMBOL GAT3, YAP5
YGL099W LSG1 conjugation with cellular fusion, sporulation (sensu Saccharomyces), ribosome nucleus export ->
conjugation, sporulation, cell organization and biogenesis, protein metabolism, transport, sexual reproduction GTPase activity ->
purine nucleotide binding, hydrolase activity\, acting on acid anhydrides cytoplasm ->
cytoplasm PHO4
Main: cell organization and biogenesis (0.80) RNA binding (0.50) nucleolus (0.80) GCR2 (0.20)
Score: 0.80 0.17 0.60 0.000
P-value: 2.107E-03 (ribosome biogenesis) 6.653E-01 (RNA binding) 7.382E-04 (nucleolus) 1.000E+00

RAP1(1) AND MCM1'(1) => SimExpr(YKL006W) OR SimExpr(other) : 15 6

EXPR: (0.224) MCM1' (P < 0.000) RAP1 (P < 0.033)

RAP1(1) AND SWI5(1) AND MCM1'(1) => SimExpr(YKL006W) OR SimExpr(other) : 5 1

EXPR: (0.178) SWI5 (P < 0.000) MCM1' (P < 0.000) RAP1 (P < 0.055)

ALPHA1(1) AND SFF'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YLR249W) OR SimExpr(other) : 10 4

RAP1(1) AND PDR(1) => SimExpr(YNL096C) : 6

EXPR: (0.164) PDR (P < 0.000) RAP1 (P < 0.004)

ORF SYMBOL P F C TF
YOR213C SAS5 chromatin silencing at telomere ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription acetyltransferase activity ->
acetyltransferase activity nuclear chromosome\, telomeric region, nuclear chromatin ->
chromosome, nuclear chromosome GRF10(Pho2), SUM1
YGR254W ENO1 gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism phosphopyruvate hydratase activity ->
phosphopyruvate hydratase activity phosphopyruvate hydratase complex, cytoplasm ->
cytoplasm FKH2, MSN4, PDR1, SWI5, YAP5
YLR441C RPS1A protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, GAT3, RAP1, YAP5
YNL096C RPS7B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, GAT3, RAP1, SFP1
YDR406W PDR15 transport ->
transport ATP-binding cassette (ABC) transporter activity ->
ATP-binding cassette (ABC) transporter activity integral to membrane ->
integral to membrane
YPR080W TEF1 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
translation elongation factor activity ribosome ->
cytoplasm, ribonucleoprotein complex FHL1, PDR1, RAP1, YAP5
Main: biosynthesis (0.67) structural constituent of ribosome (0.33) cytoplasm (0.67) RAP1 FHL1 YAP5 (0.60)
Score: 0.40 0.07 0.40 0.500
P-value: 1.961E-01 (biosynthesis) 2.565E-01 (structural constituent of ribosome) 5.038E-02 (cytosolic small ribosomal subunit (sensu Eukarya)) 8.067E-04 (YAP5)

ndt80(MSE)(1) AND SWI5(1) => SimExpr(YFR023W) OR SimExpr(other) : 16 7

ndt80(MSE)(1) AND mRRPE(1) => SimExpr(YFR023W) OR SimExpr(other) : 6 1

SFF(1) AND ndt80(MSE)(1) AND MCM1'(1) => SimExpr(YFR023W) OR SimExpr(other) : 9 2

ndt80(MSE)(1) AND SFF'(1) AND SWI5(1) AND MCM1'(1) => SimExpr(YFR023W) : 5

LYS14(1) AND mRRPE(1) AND PAC(1) => SimExpr(YMR290C) OR SimExpr(other) : 6 2

ndt80(MSE)(1) AND SWI5(1) => SimExpr(YPR122W) OR SimExpr(other) : 16 7

ndt80(MSE)(1) AND CCA(1) => SimExpr(YPR122W) OR SimExpr(other) : 5 1

ALPHA1(1) AND SFF'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YJL069C) OR SimExpr(other) : 10 4

ALPHA1'(1) AND SWI5(1) AND Ume6(URS1)(1) => SimExpr(YDR285W) OR SimExpr(other) : 5 2

EXPR: (0.213) ALPHA1' (P < 0.000) SWI5 (P < 0.000) Ume6(URS1) (P < 0.084)

ORF SYMBOL P F C TF
YNL196C NO SYMBOL
YDR285W ZIP1 meiosis, synapsis ->
cell proliferation binding ->
binding synaptonemal complex ->
chromosome, nucleus ABF1, FKH1, GCR2, GLN3, GTS1, RIM101, RTG1, SWI6
YHL024W RIM4 sporulation, meiosis, premeiotic DNA synthesis, meiotic recombination ->
sporulation, M phase, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, cell proliferation binding ->
binding cytoplasm ->
cytoplasm FKH2, PHD1
YPR007C SPO69 meiosis, sister chromatid cohesion ->
cell proliferation binding ->
binding condensed nuclear chromosome\, pericentric region, nuclear cohesin complex ->
chromosome, nuclear chromosome MCM1
YDR180W SCC2 mitotic sister chromatid cohesion ->
cell proliferation, cell cycle protein kinase activity ->
protein kinase activity nuclear cohesin complex ->
chromosome, nucleus GLN3, MSN4, ROX1
|YMR280C| CAT8 gluconeogenesis, positive regulation of transcription from Pol II promoter ->
alcohol metabolism, monosaccharide metabolism, carbohydrate metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, biosynthesis, energy pathways specific RNA polymerase II transcription factor activity ->
specific RNA polymerase II transcription factor activity nucleus ->
nucleus ABF1, REB1
|YDR091C| RLI1 binding ->
binding
Main: cell proliferation (0.80) binding (0.67) nucleus (0.60) ABF1 GLN3 (0.40)
Score: 0.70 0.40 0.50 0.200
P-value: 4.464E-03 (sister chromatid cohesion) 3.930E-01 (binding) 1.718E-03 (condensed chromosome) 4.976E-02 (GLN3)

ALPHA1(1) AND mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YJL109C) OR SimExpr(other) : 6 2

EXPR: (0.169) mRRPE (P < 0.001) PAC (P < 0.013) SCB (P < 0.000) ALPHA1 (P < 0.000)

ORF SYMBOL P F C TF
|YKL056C| NO SYMBOL
YMR131C RRB1 ribosome biogenesis ->
ribosome biogenesis nucleolus ->
nucleus FZF1, MATa1, RGT1
YJL069C UTP18 ABF1
YMR239C RNT1 35S primary transcript processing ->
ribosome biogenesis, RNA processing, transcription from Pol I promoter ribonuclease III activity ->
hydrolase activity\, acting on ester bonds, RNA binding nucleolus ->
nucleus
YJL109C UTP10 processing of 20S pre-rRNA ->
ribosome biogenesis, RNA processing, transcription from Pol I promoter snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
|YMR259C| NO SYMBOL ARG80, GCR2, GTS1, HIR1, SRD1
YJR070C NO SYMBOL GAT3, YAP5
YLR249W YEF3 translational elongation ->
translational elongation translation elongation factor activity ->
translation factor activity\, nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex INO2, INO4
Main: ribosome biogenesis (0.75) RNA binding (0.67) nucleus (0.75) GCR2 (0.20)
Score: 0.50 0.33 0.67 0.000
P-value: 4.481E-02 (ribosome biogenesis) 5.544E-01 (RNA binding) 1.842E-02 (nucleolus) 1.000E+00

ALPHA1(1) AND SFF(1) AND mRRPE(1) AND PAC(1) => SimExpr(YJL109C) OR SimExpr(other) : 9 3

ALPHA1'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YJL109C) OR SimExpr(other) : 38 9

ALPHA1(1) AND SFF'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YJL109C) OR SimExpr(other) : 11 3

ALPHA1(1) AND ALPHA1'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YJL109C) OR SimExpr(other) : 13 2

EXPR: (0.185) ALPHA1' (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.005) ALPHA1 (P < 0.000)

ALPHA1'(1) AND mRRPE(1) AND SWI5(1) AND PAC(1) => SimExpr(YJL109C) OR SimExpr(other) : 7 3

ALPHA1(1) AND SFF(1) AND SFF'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YJL109C) OR SimExpr(other) : 9 2

EXPR: (0.205) SFF (P < 0.000) SFF' (P < 0.000) mRRPE (P < 0.002) PAC (P < 0.044) ALPHA1 (P < 0.000)

ORF SYMBOL P F C TF
YOL022C NO SYMBOL MAC1, MOT3, RTS2
YCR072C NO SYMBOL YFL044C
YMR290C HAS1 nucleolus, nuclear membrane ->
nucleus, endomembrane system RAP1
YJL069C UTP18 ABF1
|YJL033W| HCA4 35S primary transcript processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus HIR2, USV1
YJL109C UTP10 processing of 20S pre-rRNA ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
|YPR183W| DPM1 N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
phospholipid biosynthesis, protein biosynthesis, glycerophospholipid metabolism, protein modification, glycoprotein metabolism, lipoprotein metabolism transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
cytoplasm, endomembrane system SWI5
YLR249W YEF3 translational elongation ->
protein biosynthesis translation elongation factor activity ->
translation factor activity\, nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex INO2, INO4
YHR169W DBP8 35S primary transcript processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus
YGL029W CGR1 ribosome biogenesis, rRNA processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent nucleolus ->
nucleus
YOR381W FRE3 iron-siderochrome transport, iron ion homeostasis ->
iron-siderochrome transport, cation homeostasis ferric-chelate reductase activity ->
oxidoreductase activity\, oxidizing metal ions plasma membrane, integral to membrane ->
plasma membrane, integral to membrane CIN5, PDR1, YAP6
Main: RNA processing (0.57) RNA binding (0.50) nucleus (0.62) ABF1 (0.12)
Score: 0.33 0.20 0.46 0.000
P-value: 3.822E-03 (rRNA processing) 2.389E-02 (ATP dependent RNA helicase activity) 2.746E-04 (nucleolus) 1.000E+00

ALPHA2(1) AND mRRPE(1) AND PAC(1) => SimExpr(YJR070C) OR SimExpr(other) : 6 3

EXPR: (0.213) ALPHA2 (P < 0.000) mRRPE (P < 0.003) PAC (P < 0.066)

ORF SYMBOL P F C TF
YKL172W EBP2 rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism nucleolus ->
nucleus ABF1, FZF1, RFX1
YHR128W FUR1 pyrimidine salvage ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism uracil phosphoribosyltransferase activity ->
transferase activity\, transferring glycosyl groups CIN5
YMR049C ERB1 rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RTG3
|YJL033W| HCA4 35S primary transcript processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus HIR2, USV1
|YPR183W| DPM1 N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
lipid biosynthesis, biosynthesis, membrane lipid metabolism, protein metabolism, lipoprotein metabolism transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
cytoplasm, endomembrane system SWI5
YJR070C NO SYMBOL GAT3, YAP5
YLR249W YEF3 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
translation factor activity\, nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex INO2, INO4
YGL029W CGR1 ribosome biogenesis, rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism nucleolus ->
nucleus
|YNR046W| NO SYMBOL ABF1
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.71) transferase activity\, transferring glycosyl groups (0.50) nucleus (0.60) ABF1 (0.25)
Score: 0.62 0.17 0.40 0.036
P-value: 1.454E-03 (rRNA processing) 1.462E-01 (transferase activity\, transferring glycosyl groups) 2.687E-02 (nucleolus) 1.000E+00

LYS14(1) AND ALPHA1'(1) AND PAC(1) => SimExpr(YJR070C) OR SimExpr(other) : 7 2

EXPR: (0.234) LYS14 (P < 0.001) ALPHA1' (P < 0.000) PAC (P < 0.169)

ORF SYMBOL P F C TF
|YOL075C| NO SYMBOL CRZ1, DAL82, SIP4
YHR128W FUR1 pyrimidine salvage ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism uracil phosphoribosyltransferase activity ->
transferase activity\, transferring glycosyl groups CIN5
YML093W UTP14 processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding nucleolus ->
nucleus
YJR070C NO SYMBOL GAT3, YAP5
YGL099W LSG1 conjugation with cellular fusion, sporulation (sensu Saccharomyces), ribosome nucleus export ->
conjugation, sporulation, cell organization and biogenesis, protein metabolism, transport, sexual reproduction GTPase activity ->
purine nucleotide binding, hydrolase activity\, acting on acid anhydrides cytoplasm ->
cytoplasm PHO4
YDR361C BCP1 ABF1, ARO80, GLN3, HAP5, IXR1, YAP1
YGR191W HIP1 manganese ion transport, histidine transport ->
transport, organic acid transport histidine transporter activity ->
carboxylic acid transporter activity plasma membrane ->
plasma membrane GLN3, HAP3, HIR2, MBP1, MCM1, REB1, YAP1
|YGR178C| PBP1 mRNA polyadenylation ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism cytoplasm, nucleus ->
cytoplasm, nucleus CIN5, DOT6, MSS11
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.67) RNA binding (0.40) nucleus (0.60) CIN5 YAP1 GLN3 (0.29)
Score: 0.60 0.10 0.40 0.095
P-value: 6.921E-02 (ribosome biogenesis) 8.159E-01 (RNA binding) 3.071E-01 (nucleolus) 1.198E-01 (GLN3)

ALPHA1(1) AND ALPHA1'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YJR070C) OR SimExpr(other) : 13 2

LYS14(1) AND ALPHA1'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YJR070C) : 5

EXPR: (0.133) LYS14 (P < 0.000) ALPHA1' (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.001)

ORF SYMBOL P F C TF
YHR128W FUR1 pyrimidine salvage ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism uracil phosphoribosyltransferase activity ->
transferase activity\, transferring glycosyl groups CIN5
YML093W UTP14 processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleolus, ribonucleoprotein complex
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding nucleolus ->
nucleolus
YJR070C NO SYMBOL GAT3, YAP5
YGL099W LSG1 conjugation with cellular fusion, sporulation (sensu Saccharomyces), ribosome nucleus export ->
conjugation, sporulation, cell organization and biogenesis, protein metabolism, transport, sexual reproduction GTPase activity ->
purine nucleotide binding, hydrolase activity\, acting on acid anhydrides cytoplasm ->
cytoplasm PHO4
Main: cell organization and biogenesis (0.75) RNA binding (0.50) nucleolus (0.67) GAT3 (0.33)
Score: 0.83 0.17 0.33 0.000
P-value: 8.699E-03 (ribosome biogenesis) 2.743E-01 (RNA binding) 8.076E-02 (nucleolus) 3.025E-01 (GAT3)

SFF(1) AND ndt80(MSE)(1) => SimExpr(YMR001C) OR SimExpr(other) : 27 10

ALPHA1(1) AND ndt80(MSE)(1) AND SFF'(1) => SimExpr(YMR001C) OR SimExpr(other) : 13 6

EXPR: (0.248) ndt80(MSE) (P < 0.455) SFF' (P < 0.000) ALPHA1 (P < 0.000)

ORF SYMBOL P F C TF
YJL160C NO SYMBOL ACE2, HIR2, MCM1, SWI5
YPR122W AXL1 axial budding, bud site selection, conjugation with cellular fusion, peptide pheromone maturation ->
asexual reproduction, conjugation, protein metabolism, cell proliferation, cell organization and biogenesis, sexual reproduction metalloendopeptidase activity ->
endopeptidase activity, metallopeptidase activity integral to membrane, bud neck, shmoo tip ->
integral to membrane, site of polarized growth (sensu Fungi) CIN5
|YHR207C| SET5 LEU3, PHO4
|YGR060W| ERG25 ergosterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism C-4 methyl sterol oxidase activity ->
C-4 methyl sterol oxidase activity endoplasmic reticulum membrane, plasma membrane ->
cytoplasm, plasma membrane, endomembrane system HSF1, MAL13, MET4, NDD1, SWI5
YNR034W SOL1 tRNA processing ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism YFL044C
YNL034W NO SYMBOL MAC1, MET4, NDD1, RME1
YFR023W PES4 DNA dependent DNA replication ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DIG1, FKH1, FKH2, GLN3, HAP3, MCM1, MSN2, RIM101, RLM1, RTG3, STE12, SUM1, THI2, YAP1
YMR125W STO1 mRNA splicing ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism mRNA binding ->
mRNA binding commitment complex, snRNA cap binding complex ->
nucleus, cytoplasm, ribonucleoprotein complex ABF1, FZF1, HAP3, MET31, RTG1, SRD1, SUM1, YAP6, ZAP1
YOL132W GAS4 cell wall (sensu Fungi) ->
cell wall
YGL116W CDC20 mitotic spindle elongation, ubiquitin-dependent protein catabolism, mitotic metaphase/anaphase transition, mitotic chromosome segregation, cyclin catabolism ->
cell organization and biogenesis, catabolism, cell proliferation, cell cycle, protein metabolism enzyme activator activity ->
enzyme activator activity anaphase-promoting complex ->
nucleus, ubiquitin ligase complex DIG1, FKH2, INO2, INO4, IXR1, MCM1, NDD1
|YOR388C| FDH1 formate catabolism, NADH regeneration ->
catabolism, coenzymes and prosthetic group metabolism, one-carbon compound metabolism, vitamin metabolism, organic acid metabolism formate dehydrogenase activity ->
oxidoreductase activity\, acting on the aldehyde or oxo group of donors\, NAD or NADP as acceptor cytosol ->
cytoplasm MCM1, YJL206C
YBR115C LYS2 lysine biosynthesis\, aminoadipic pathway ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis aminoadipate-semialdehyde dehydrogenase activity ->
oxidoreductase activity\, acting on the aldehyde or oxo group of donors\, NAD or NADP as acceptor cytoplasm ->
cytoplasm DAL81, GCN4
YDR438W NO SYMBOL CBF1
|YGL189C| RPS26A protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, GAT3, PDR1, RAP1, RGM1, YAP5
YDR218C SPR28 cellular morphogenesis, cell wall organization and biogenesis ->
cell organization and biogenesis structural constituent of cytoskeleton ->
structural constituent of cytoskeleton septin ring (sensu Saccharomyces) ->
site of polarized growth (sensu Fungi), cell cortex, cytoskeleton YAP6
|YGL121C| GPG1 signal transduction ->
signal transduction signal transducer activity ->
signal transducer activity CHA4
YOR214C NO SYMBOL BAS1
|YMR280C| CAT8 gluconeogenesis, positive regulation of transcription from Pol II promoter ->
alcohol metabolism, monosaccharide metabolism, carbohydrate metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, biosynthesis, energy pathways specific RNA polymerase II transcription factor activity ->
specific RNA polymerase II transcription factor activity nucleus ->
nucleus ABF1, REB1
YMR001C CDC5 DNA dependent DNA replication, protein amino acid phosphorylation ->
phosphorus metabolism, cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism protein serine/threonine kinase activity ->
phosphotransferase activity\, alcohol group as acceptor nucleus, spindle pole, bud neck ->
nucleus, cytoplasm, site of polarized growth (sensu Fungi) NDD1, REB1, SWI6
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.38) oxidoreductase activity\, acting on the aldehyde or oxo group of donors\, NAD or NADP as acceptor (0.18) cytoplasm (0.55) NDD1 MCM1 (0.22)
Score: 0.36 0.02 0.42 0.111
P-value: 1.825E+00 (DNA dependent DNA replication) 4.899E-02 (oxidoreductase activity\, acting on the aldehyde or oxo group of donors\, NAD or NADP as acceptor) 1.555E-01 (bud neck) 7.065E-02 (NDD1)

ALPHA1(1) AND SFF(1) AND ndt80(MSE)(1) => SimExpr(YMR001C) OR SimExpr(other) : 11 2

EXPR: (0.198) SFF (P < 0.000) ndt80(MSE) (P < 0.097) ALPHA1 (P < 0.000)

ORF SYMBOL P F C TF
YNR034W SOL1 tRNA processing ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism YFL044C
YNL034W NO SYMBOL MAC1, MET4, NDD1, RME1
YFR023W PES4 DNA dependent DNA replication ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DIG1, FKH1, FKH2, GLN3, HAP3, MCM1, MSN2, RIM101, RLM1, RTG3, STE12, SUM1, THI2, YAP1
YOL132W GAS4 cell wall (sensu Fungi) ->
cell wall
YGL116W CDC20 mitotic spindle elongation, ubiquitin-dependent protein catabolism, mitotic metaphase/anaphase transition, mitotic chromosome segregation, cyclin catabolism ->
cell organization and biogenesis, catabolism, cell proliferation, cell cycle, protein metabolism enzyme activator activity ->
enzyme activator activity anaphase-promoting complex ->
nucleus, ubiquitin ligase complex DIG1, FKH2, INO2, INO4, IXR1, MCM1, NDD1
YBR115C LYS2 lysine biosynthesis\, aminoadipic pathway ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis aminoadipate-semialdehyde dehydrogenase activity ->
aminoadipate-semialdehyde dehydrogenase activity cytoplasm ->
cytoplasm DAL81, GCN4
YLR049C NO SYMBOL MBP1, SWI5
YDR438W NO SYMBOL CBF1
YDR218C SPR28 cellular morphogenesis, cell wall organization and biogenesis ->
cell organization and biogenesis structural constituent of cytoskeleton ->
structural constituent of cytoskeleton septin ring (sensu Saccharomyces) ->
site of polarized growth (sensu Fungi), cell cortex, cytoskeleton YAP6
|YGL121C| GPG1 signal transduction ->
signal transduction signal transducer activity ->
signal transducer activity CHA4
YOR214C NO SYMBOL BAS1
|YMR280C| CAT8 gluconeogenesis, positive regulation of transcription from Pol II promoter ->
alcohol metabolism, monosaccharide metabolism, carbohydrate metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, biosynthesis, energy pathways specific RNA polymerase II transcription factor activity ->
specific RNA polymerase II transcription factor activity nucleus ->
nucleus ABF1, REB1
YMR001C CDC5 DNA dependent DNA replication, protein amino acid phosphorylation ->
phosphorus metabolism, cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism protein serine/threonine kinase activity ->
protein serine/threonine kinase activity nucleus, spindle pole, bud neck ->
nucleus, cytoplasm, site of polarized growth (sensu Fungi) NDD1, REB1, SWI6
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.50) signal transducer activity (0.17) nucleus (0.50) NDD1 (0.25)
Score: 0.36 0.00 0.33 0.076
P-value: 5.608E-01 (DNA dependent DNA replication) 2.997E+00 (enzyme activity) 4.713E-01 (bud neck) 1.459E-01 (NDD1)

ALPHA1(1) AND ndt80(MSE)(1) AND MCM1'(1) => SimExpr(YMR001C) OR SimExpr(other) : 6 2

EXPR: (0.177) ndt80(MSE) (P < 0.068) MCM1' (P < 0.000) ALPHA1 (P < 0.000)

ORF SYMBOL P F C TF
YNR034W SOL1 tRNA processing ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism YFL044C
YFR023W PES4 DNA dependent DNA replication ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DIG1, FKH1, FKH2, GLN3, HAP3, MCM1, MSN2, RIM101, RLM1, RTG3, STE12, SUM1, THI2, YAP1
YGL116W CDC20 mitotic spindle elongation, ubiquitin-dependent protein catabolism, mitotic metaphase/anaphase transition, mitotic chromosome segregation, cyclin catabolism ->
cell organization and biogenesis, catabolism, cell proliferation, cell cycle, protein metabolism enzyme activator activity ->
enzyme activator activity anaphase-promoting complex ->
nucleus, ubiquitin ligase complex DIG1, FKH2, INO2, INO4, IXR1, MCM1, NDD1
YDR273W DON1 meiosis, spore wall assembly (sensu Saccharomyces) ->
cell proliferation, sporulation spindle, prospore membrane ->
cytoplasm, prospore
YPL130W SPO19 meiosis ->
cell proliferation cell wall (sensu Fungi) ->
cell wall GRF10(Pho2), HAP2, MOT3
|YOR388C| FDH1 formate catabolism, NADH regeneration ->
catabolism, coenzymes and prosthetic group metabolism, one-carbon compound metabolism, vitamin metabolism, organic acid metabolism formate dehydrogenase activity ->
formate dehydrogenase activity cytosol ->
cytoplasm MCM1, YJL206C
|YBR069C| TAT1 amino acid transport ->
transport amino acid transporter activity ->
amino acid transporter activity plasma membrane ->
plasma membrane CIN5, DAL81, PHD1, SWI4
YMR001C CDC5 DNA dependent DNA replication, protein amino acid phosphorylation ->
phosphorus metabolism, cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism protein serine/threonine kinase activity ->
protein serine/threonine kinase activity nucleus, spindle pole, bud neck ->
nucleus, cytoplasm, site of polarized growth (sensu Fungi) NDD1, REB1, SWI6
Main: cell proliferation (0.62) protein serine/threonine kinase activity (0.25) cytoplasm (0.50) MCM1 (0.43)
Score: 0.46 0.00 0.27 0.190
P-value: 2.166E-02 (cell cycle) 2.924E+00 (enzyme activity) 1.050E-01 (spindle) 5.811E-02 (MCM1)

SFF(1) AND ndt80(MSE)(1) AND MCM1'(1) => SimExpr(YMR001C) OR SimExpr(other) : 9 2

ndt80(MSE)(1) AND SFF'(1) AND SWI5(1) AND MCM1'(1) => SimExpr(YMR001C) : 5

ALPHA1(1) AND SFF(1) AND ndt80(MSE)(1) => SimExpr(YNR034W) OR SimExpr(other) : 11 2

ALPHA2(1) AND ALPHA1'(1) AND RPN4(1) => SimExpr(YOL038W) OR SimExpr(other) : 5 2

EXPR: (0.235) ALPHA2 (P < 0.000) ALPHA1' (P < 0.000) RPN4 (P < 0.092)

ORF SYMBOL P F C TF
YGR060W ERG25 ergosterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism C-4 methyl sterol oxidase activity ->
C-4 methyl sterol oxidase activity endoplasmic reticulum membrane, plasma membrane ->
cytoplasm, plasma membrane, endomembrane system HSF1, MAL13, MET4, NDD1, SWI5
YOL038W PRE6 ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism endopeptidase activity ->
peptidase activity proteasome core complex (sensu Eukarya) ->
cytoplasm, nucleus
|YGR184C| UBR1 protein polyubiquitination, protein monoubiquitination ->
catabolism, protein metabolism ubiquitin-protein ligase activity ->
ligase activity\, forming carbon-nitrogen bonds proteasome complex (sensu Eukarya) ->
cytoplasm, nucleus HMS1, REB1, RIM101
YDL126C CDC48 ubiquitin-dependent protein catabolism, nonselective vesicle fusion, cell cycle, apoptosis, protein transport, ER-associated protein catabolism ->
cell proliferation, cell death, macromolecule catabolism, transport, protein metabolism ATPase activity ->
purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleus, microsome, endoplasmic reticulum, cytosol ->
nucleus, membrane fraction, cytoplasm DAL82, MAL33, SWI4
|YBL022C| PIM1 proteolysis and peptidolysis, response to heat ->
catabolism, response to abiotic stimulus, protein metabolism ATP-dependent peptidase activity ->
peptidase activity mitochondrial matrix ->
cytoplasm RAP1
YDR212W TCP1 protein folding, cytoskeleton organization and biogenesis ->
protein metabolism, cell organization and biogenesis chaperone activity ->
chaperone activity cytoplasm, cytoskeleton ->
cytoplasm
YKL054C DEF1 response to DNA damage, ubiquitin-dependent protein catabolism ->
response to biotic stimulus, catabolism, protein metabolism nucleus ->
nucleus
Main: protein metabolism (0.86) peptidase activity (0.33) cytoplasm (0.86) SWI4 (0.25)
Score: 0.71 0.07 0.86 0.000
P-value: 1.376E-05 (proteolysis and peptidolysis) 8.873E-02 (peptidase activity) 7.428E-03 (endoplasmic reticulum) 4.110E-01 (MAL33)

mRRPE(1) AND PAC(1) => SimExpr(YKL172W) OR SimExpr(other) : 60 23

mRRPE(1) AND PAC(1) => SimExpr(YGR187C) OR SimExpr(other) : 59 24

ALPHA1'(1) AND SWI5(1) AND Ume6(URS1)(1) => SimExpr(YHL024W) OR SimExpr(other) : 5 2

LYS14(1) AND mRRPE(1) AND PAC(1) => SimExpr(YML093W) OR SimExpr(other) : 6 2

LYS14(1) AND RPN4(1) => SimExpr(YNL012W) OR SimExpr(other) : 9 3

EXPR: (0.212) LYS14 (P < 0.000) RPN4 (P < 0.012)

ndt80(MSE)(1) AND mRRPE(1) => SimExpr(YOL091W) OR SimExpr(other) : 6 1

ALPHA1'(1) AND SWI5(1) AND Ume6(URS1)(1) => SimExpr(YPR007C) OR SimExpr(other) : 5 2

ndt80(MSE)(1) AND PDR(1) => SimExpr(YDR281C) OR SimExpr(other) : 5 2

EXPR: (0.180) ndt80(MSE) (P < 0.023) PDR (P < 0.000)

ORF SYMBOL P F C TF
YKL096W CWP1 cell wall organization and biogenesis ->
cell wall organization and biogenesis structural constituent of cell wall ->
structural constituent of cell wall cell wall (sensu Fungi) ->
cell wall (sensu Fungi) RLM1, SMP1, STE12, SWI4
|YCR045C| NO SYMBOL
|YBR159W| NO SYMBOL ACE2, ARG81, GCR2, HIR2, LEU3, MOT3, PDR1, PHD1, SKN7, USV1
YDR317W NO SYMBOL HAL9, RLM1
YMR252C NO SYMBOL SKN7
YDR281C PHM6 PHO4, SUM1
YOR338W NO SYMBOL RAP1
Main: cell wall organization and biogenesis (1.00) structural constituent of cell wall (1.00) cell wall (sensu Fungi) (1.00) RLM1 SKN7 (0.33)
Score: 0.00 0.00 0.00 0.133
P-value: 0.000E+00 0.000E+00 0.000E+00 1.672E-01 (RLM1)

ndt80(MSE)(1) AND CCA(1) => SimExpr(YGL230C) OR SimExpr(other) : 5 1

SFF(1) AND ndt80(MSE)(1) => SimExpr(YHR184W) OR SimExpr(other) : 25 12

ndt80(MSE)(1) AND mRRPE(1) => SimExpr(YOR339C) OR SimExpr(other) : 6 1

ndt80(MSE)(1) AND mRRPE(1) => SimExpr(YOR338W) OR SimExpr(other) : 6 1

GCN4(1) AND Leu3(1) => SimExpr(YJR016C) OR SimExpr(other) : 5 1

EXPR: (0.210) GCN4 (P < 0.003) Leu3 (P < 0.004)

ORF SYMBOL P F C TF
YLR355C ILV5 branched chain family amino acid biosynthesis, mitochondrial genome maintenance ->
amino acid biosynthesis, mitochondrion organization and biogenesis, branched chain family amino acid metabolism ketol-acid reductoisomerase activity ->
oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor mitochondrion ->
cytoplasm GCN4, MET4
YOR108W LEU9 leucine biosynthesis ->
amino acid biosynthesis, branched chain family amino acid metabolism 2-isopropylmalate synthase activity ->
oxo-acid-lyase activity mitochondrion ->
cytoplasm AZF1, GCN4, LEU3
|YDL194W| SNF3 signal transduction, response to glucose stimulus ->
signal transduction, response to glucose stimulus receptor activity, glucose binding, glucose transporter activity ->
receptor activity, monosaccharide binding, hexose transporter activity plasma membrane ->
plasma membrane
YGL009C LEU1 leucine biosynthesis ->
amino acid biosynthesis, branched chain family amino acid metabolism 3-isopropylmalate dehydratase activity ->
hydro-lyase activity cytosol ->
cytoplasm LEU3
YDR158W HOM2 homoserine biosynthesis, threonine metabolism, methionine metabolism ->
amino acid biosynthesis, aspartate family amino acid metabolism, homoserine metabolism, serine family amino acid metabolism, sulfur amino acid metabolism aspartate-semialdehyde dehydrogenase activity ->
oxidoreductase activity\, acting on the aldehyde or oxo group of donors\, NAD or NADP as acceptor ACE2, HSF1, NDD1, REB1, SKN7, SWI5
YJR016C ILV3 branched chain family amino acid biosynthesis ->
amino acid biosynthesis, branched chain family amino acid metabolism dihydroxy-acid dehydratase activity ->
hydro-lyase activity mitochondrion ->
cytoplasm
Main: amino acid biosynthesis (0.83) hydro-lyase activity (0.33) cytoplasm (0.80) LEU3 GCN4 (0.50)
Score: 0.67 0.07 0.60 0.333
P-value: 6.193E-08 (branched chain family amino acid biosynthesis) 4.845E-03 (lyase activity) 1.878E-01 (mitochondrion) 1.596E-02 (LEU3)

SFF'(1) AND GCN4(1) AND Leu3(1) => SimExpr(YJR016C) : 5

EXPR: (0.139) SFF' (P < 0.000) GCN4 (P < 0.000) Leu3 (P < 0.002)

AVERAGE SCORES:

P
  SCORE: 0.515 (Part of genes covered by "Main": 0.643) (No. rules=43/45)
  P-VALUE: 0.535
F
  SCORE: 0.169 (Part of genes covered by "Main": 0.419) (No. rules=42/45)
  P-VALUE: 0.262
C
  SCORE: 0.550 (Part of genes covered by "Main": 0.685) (No. rules=43/45)
  P-VALUE: 0.442
TF
  SCORE: 0.166 (Part of genes covered by "Main": 0.338) (No. rules=45/45)
  P-VALUE: 0.133
EXPRESSION: 0.578 (45)

ORF	SYMBOL	P	F	C	TF
YDR042C	NO SYMBOL				ARG80, ARG81, AZF1, CIN5, CUP9, DIG1, FZF1, GCR2, HAL9, HAP2, HAP4, HAP5, HIR2, HMS1, IXR1, LEU3, MBP1, MCM1, MET31, NRG1, PDR1, RLM1, RME1, ROX1, RTG1, RTG3, SRD1, STE12, SUM1, YAP6, ZAP1
\|YCR045C\|	NO SYMBOL
YJR007W	SUI2	translational initiation -> biosynthesis, protein metabolism	translation initiation factor activity -> translation initiation factor activity	ribosome, cytoplasm -> cytoplasm, ribonucleoprotein complex	GLN3, HAP3, HIR1, RCS1
\|YBR159W\|	NO SYMBOL				ACE2, ARG81, GCR2, HIR2, LEU3, MOT3, PDR1, PHD1, SKN7, USV1
\|YNL196C\|	NO SYMBOL
YOR338W	NO SYMBOL				RAP1
YNL034W	NO SYMBOL				MAC1, MET4, NDD1, RME1
YMR001C	CDC5	DNA dependent DNA replication, protein amino acid phosphorylation -> phosphorus metabolism, cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism	protein serine/threonine kinase activity -> protein serine/threonine kinase activity	nucleus, spindle pole, bud neck -> nucleus, cytoplasm, site of polarized growth (sensu Fungi)	NDD1, REB1, SWI6
\|YLR154C\|	RNH203				RLM1
YFR023W	PES4	DNA dependent DNA replication -> cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism			DIG1, FKH1, FKH2, GLN3, HAP3, MCM1, MSN2, RIM101, RLM1, RTG3, STE12, SUM1, THI2, YAP1
\|YMR280C\|	CAT8	gluconeogenesis, positive regulation of transcription from Pol II promoter -> alcohol metabolism, monosaccharide metabolism, carbohydrate metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, biosynthesis, energy pathways	specific RNA polymerase II transcription factor activity -> specific RNA polymerase II transcription factor activity	nucleus -> nucleus	ABF1, REB1
YFR012W	NO SYMBOL				DAL81
YOL132W	GAS4			cell wall (sensu Fungi) -> cell wall
YHR124W	NDT80	meiosis, transcription -> cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	transcription factor activity -> transcription factor activity	nuclear chromosome -> chromosome, nucleus	SUM1
YBR069C	TAT1	amino acid transport -> transport	amino acid transporter activity -> amino acid transporter activity	plasma membrane -> plasma membrane	CIN5, DAL81, PHD1, SWI4
YKL104C	GFA1	cell wall chitin biosynthesis -> cell organization and biogenesis, biosynthesis, polysaccharide metabolism, carbohydrate metabolism	glucosamine-fructose-6-phosphate aminotransferase (isomerizing) activity -> glucosamine-fructose-6-phosphate aminotransferase (isomerizing) activity		REB1
YFR032C	NO SYMBOL				PUT3, SUM1
YOR214C	NO SYMBOL				BAS1
YGL116W	CDC20	mitotic spindle elongation, ubiquitin-dependent protein catabolism, mitotic metaphase/anaphase transition, mitotic chromosome segregation, cyclin catabolism -> cell organization and biogenesis, catabolism, cell proliferation, cell cycle, protein metabolism	enzyme activator activity -> enzyme activator activity	anaphase-promoting complex -> nucleus, ubiquitin ligase complex	DIG1, FKH2, INO2, INO4, IXR1, MCM1, NDD1
YLR049C	NO SYMBOL				MBP1, SWI5
\|YHL043W\|	ECM34	cell wall organization and biogenesis -> cell organization and biogenesis
YPR122W	AXL1	axial budding, bud site selection, conjugation with cellular fusion, peptide pheromone maturation -> asexual reproduction, conjugation, protein metabolism, cell proliferation, cell organization and biogenesis, sexual reproduction	metalloendopeptidase activity -> metalloendopeptidase activity	integral to membrane, bud neck, shmoo tip -> integral to membrane, site of polarized growth (sensu Fungi)	CIN5
\|YKR005C\|	NO SYMBOL
Main:		cell proliferation (0.50)	metalloendopeptidase activity (0.12)	nucleus (0.50)	SUM1 (0.22)
Score:		0.53	0.00	0.29	0.163
P-value:		2.212E+00 (carbohydrate biosynthesis)	4.226E+00 (transcription regulator activity)	1.310E+00 (bud neck)	4.860E-02 (SUM1)

ORF	SYMBOL	P	F	C	TF
YNR034W	SOL1	tRNA processing -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism			YFL044C
YKL096W	CWP1	cell wall organization and biogenesis -> cell organization and biogenesis	structural constituent of cell wall -> structural constituent of cell wall	cell wall (sensu Fungi) -> cell wall	RLM1, SMP1, STE12, SWI4
YFR023W	PES4	DNA dependent DNA replication -> cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism			DIG1, FKH1, FKH2, GLN3, HAP3, MCM1, MSN2, RIM101, RLM1, RTG3, STE12, SUM1, THI2, YAP1
YGL116W	CDC20	mitotic spindle elongation, ubiquitin-dependent protein catabolism, mitotic metaphase/anaphase transition, mitotic chromosome segregation, cyclin catabolism -> cell organization and biogenesis, catabolism, cell proliferation, cell cycle, protein metabolism	enzyme activator activity -> enzyme activator activity	anaphase-promoting complex -> nucleus, ubiquitin ligase complex	DIG1, FKH2, INO2, INO4, IXR1, MCM1, NDD1
YJR007W	SUI2	translational initiation -> biosynthesis, protein metabolism	translation initiation factor activity -> translation initiation factor activity	ribosome, cytoplasm -> cytoplasm, ribonucleoprotein complex	GLN3, HAP3, HIR1, RCS1
YGL230C	NO SYMBOL				HIR1, MATa1
YPL255W	BBP1	microtubule nucleation -> cell organization and biogenesis	structural constituent of cytoskeleton -> structural constituent of cytoskeleton	spindle pole body -> cytoplasm	STB1, SWI4
\|YOL028C\|	YAP7	positive regulation of transcription from Pol II promoter -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription	RNA polymerase II transcription factor activity -> RNA polymerase II transcription factor activity	nucleus -> nucleus	NRG1
YLR308W	CDA2	spore wall assembly (sensu Saccharomyces) -> sporulation	chitin deacetylase activity -> chitin deacetylase activity	chitosan layer of spore wall -> cell wall	REB1, SUM1
\|YMR204C\|	NO SYMBOL				STE12
YMR001C	CDC5	DNA dependent DNA replication, protein amino acid phosphorylation -> phosphorus metabolism, cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism	protein serine/threonine kinase activity -> protein serine/threonine kinase activity	nucleus, spindle pole, bud neck -> nucleus, cytoplasm, site of polarized growth (sensu Fungi)	NDD1, REB1, SWI6
Main:		nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.44)	structural constituent of cell wall (0.14)	cytoplasm (0.43)	STE12 (0.27)
Score:		0.36	0.00	0.33	0.182
P-value:		4.087E-01 (microtubule cytoskeleton organization and biogenesis)	1.148E+00 (structural molecule activity)	1.882E-01 (spindle pole)	5.856E-02 (STE12)

ORF	SYMBOL	P	F	C	TF
\|YHL008C\|	NO SYMBOL				RFX1, RTG1, YJL206C
YDR116C	MRPL1	protein biosynthesis, meiosis, aerobic respiration -> protein biosynthesis, M phase, cellular respiration	structural constituent of ribosome -> structural constituent of ribosome	mitochondrial large ribosomal subunit -> cytoplasm, ribonucleoprotein complex	CHA4, GRF10(Pho2)
\|YGR142W\|	BTN2	regulation of pH, intracellular protein transport -> cation homeostasis, intracellular protein transport		cytosol -> cytoplasm	HSF1, MSN4
YLL010C	PSR1	response to stress -> response to stress	protein phosphatase activity -> protein phosphatase activity	plasma membrane -> plasma membrane	CBF1
YKL185W	ASH1	regulation of transcription\, mating-type specific, pseudohyphal growth -> mating-type determination, growth pattern, regulation of transcription, transcription\, DNA-dependent	specific transcriptional repressor activity -> specific transcriptional repressor activity	nucleus -> nucleus	SMP1, SWI5
YGR280C	PXR1	35S primary transcript processing, snRNA processing -> ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent	RNA binding -> RNA binding	nucleolus -> nucleus
YOR086C	NO SYMBOL				ABF1, STE12
Main:		transcription\, DNA-dependent (0.40)	RNA binding (0.25)	cytoplasm (0.40)	ABF1 (0.17)
Score:		0.10	0.00	0.20	0.000
P-value:		1.864E+00 (transcription\, DNA-dependent)	2.000E+00	4.535E+00 (nucleus)	9.217E-01 (CHA4)

ORF	SYMBOL	P	F	C	TF
YAL059W	ECM1	cell wall organization and biogenesis -> cell growth and/or maintenance			MOT3
YNL132W	KRE33
\|YOL022C\|	NO SYMBOL				MAC1, MOT3, RTS2
YFR001W	LOC1	ribosomal large subunit biogenesis -> cell growth and/or maintenance	mRNA binding -> RNA binding	nucleus -> nucleus	ARG80, GAL4, GTS1, HAP4, HIR1, LEU3, MSN2, MSN4, RCS1, RLM1, SWI4
YDR496C	PUF6				RFX1
\|YLR276C\|	DBP9	ribosomal large subunit assembly and maintenance, 35S primary transcript processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ATP dependent RNA helicase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleolus -> nucleus	MATa1, RCS1, RTG3, SWI5
\|YGL169W\|	SUA5	cell growth and/or maintenance -> cell growth and/or maintenance			ABF1
YLR002C	NOC3	DNA replication initiation, rRNA processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription	chromatin binding, protein binding -> DNA binding, protein binding	nucleus, nucleolus -> nucleus	HIR1, IXR1, RCS1
\|YDR279W\|	RNH202				GCR2, MBP1, RIM101, RLM1, SWI6, THI2
YCR072C	NO SYMBOL				YFL044C
\|YHR128W\|	FUR1	pyrimidine salvage -> biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	uracil phosphoribosyltransferase activity -> transferase activity\, transferring glycosyl groups		CIN5
YNL175C	NOP13		RNA binding -> RNA binding	nucleolus, nucleoplasm -> nucleus	INO2, INO4
\|YOR078W\|	BUD21	processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	ABF1, MSS11, SIG1, SKO1
YPR010C	RPA135	transcription from Pol I promoter -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	DNA-directed RNA polymerase activity -> transferase activity\, transferring phosphorus-containing groups	DNA-directed RNA polymerase I complex -> nucleus	ROX1, SIG1
YKL014C	NO SYMBOL				ABF1
YDR184C	ATC1	response to stress, polar budding -> response to stress, asexual reproduction		nucleus -> nucleus	ARO80, GLN3, SIP4, SKO1
YML093W	UTP14	processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex
YMR229C	RRP5	rRNA processing, processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	RNA binding, snoRNA binding -> RNA binding	nucleolus, nucleolus organizer complex -> nucleus	FHL1, RAP1
\|YNR024W\|	NO SYMBOL
YBR104W	YMC2	transport -> cell growth and/or maintenance	transporter activity -> transporter activity	mitochondrial inner membrane -> cytoplasm, inner membrane	FKH1, FKH2
\|YGL171W\|	ROK1	35S primary transcript processing, mRNA splicing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ATP dependent RNA helicase activity, ATPase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleolus -> nucleus	RGT1
YOR095C	RKI1	pentose-phosphate shunt -> coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism	ribose-5-phosphate isomerase activity -> intramolecular isomerase activity		FHL1, FKH2, RAP1
YMR049C	ERB1	rRNA processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism			RTG3
\|YJL033W\|	HCA4	35S primary transcript processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ATP dependent RNA helicase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleolus -> nucleus	HIR2, USV1
YNL075W	IMP4	rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription	rRNA primary transcript binding -> RNA binding	small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	USV1
YNL112W	DBP2		RNA helicase activity -> RNA binding	bud neck -> site of polarized growth (sensu Fungi)
\|YCR090C\|	NO SYMBOL
\|YNL308C\|	KRI1	ribosome biogenesis -> cell growth and/or maintenance		nucleolus -> nucleus
YGR245C	SDA1	actin cytoskeleton organization and biogenesis, start control point of mitotic cell cycle -> cell growth and/or maintenance		nucleus -> nucleus
\|YCL059C\|	KRR1	ribosome biogenesis, rRNA processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism		nucleolus -> nucleus
YNR053C	NOG2	mRNA splicing -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	GTPase activity -> purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleus, nucleolus, nucleoplasm -> nucleus, nucleoplasm	ABF1, AZF1
\|YNL292W\|	PUS4	tRNA modification -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	pseudouridylate synthase activity -> carbon-oxygen lyase activity	mitochondrion, nucleus -> cytoplasm, nucleus	RCS1
YJL109C	UTP10	processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex
YGR280C	PXR1	35S primary transcript processing, snRNA processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	RNA binding -> RNA binding	nucleolus -> nucleus
YDR449C	UTP6	processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	FHL1, GAT3, HIR2, RAP1, RGM1, YAP5
YHR196W	UTP9	processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex, nucleolus, nucleus -> nucleus, ribonucleoprotein complex
\|YPR183W\|	DPM1	N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis -> lipid biosynthesis, biosynthesis, membrane lipid metabolism, protein metabolism, lipoprotein metabolism	transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity -> transferase activity\, transferring glycosyl groups	endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network -> cytoplasm, endomembrane system	SWI5
YJR070C	NO SYMBOL				GAT3, YAP5
YGL099W	LSG1	conjugation with cellular fusion, sporulation (sensu Saccharomyces), ribosome nucleus export -> conjugation, protein metabolism, cell growth and/or maintenance, sexual reproduction	GTPase activity -> purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	cytoplasm -> cytoplasm	PHO4
YGR162W	TIF4631	translational initiation -> biosynthesis, protein metabolism	translation initiation factor activity -> translation factor activity\, nucleic acid binding	ribosome -> cytoplasm, ribonucleoprotein complex	HSF1
YOR359W	VTS1	protein-vacuolar targeting -> protein metabolism, cell growth and/or maintenance	intracellular transporter activity -> transporter activity	cytosol -> cytoplasm	RAP1
YOR310C	NOP58	rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription		small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	ABF1, SWI6
YHR169W	DBP8	35S primary transcript processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ATP dependent RNA helicase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleolus -> nucleus
YGL029W	CGR1	ribosome biogenesis, rRNA processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism		nucleolus -> nucleus
YOR381W	FRE3	iron-siderochrome transport, iron ion homeostasis -> cell growth and/or maintenance	ferric-chelate reductase activity -> oxidoreductase activity\, oxidizing metal ions	plasma membrane, integral to membrane -> plasma membrane, integral to membrane	CIN5, PDR1, YAP6
YOR272W	YTM1	chromosome organization and biogenesis (sensu Eukarya), ribosomal large subunit biogenesis -> cell growth and/or maintenance		nucleus, nucleolus -> nucleus	LEU3, PUT3, REB1
\|YCR016W\|	NO SYMBOL
Main:		cell growth and/or maintenance (0.77)	RNA binding (0.56)	nucleus (0.78)	ABF1 (0.15)
Score:		0.73	0.33	0.65	0.066
P-value:		2.029E-17 (ribosome biogenesis)	8.994E-08 (snoRNA binding)	3.877E-18 (nucleolus)	6.159E-01 (RCS1)

ORF	SYMBOL	P	F	C	TF
\|YKL120W\|	OAC1	oxaloacetate transport, sulfate transport -> transport	oxaloacetate carrier activity, sulfate porter activity -> electrochemical potential-driven transporter activity, anion transporter activity, organic cation transporter activity, carboxylic acid transporter activity	mitochondrial inner membrane -> cytoplasm, inner membrane	LEU3, MTH1
YLL010C	PSR1	response to stress -> response to stress	protein phosphatase activity -> hydrolase activity\, acting on ester bonds	plasma membrane -> plasma membrane	CBF1
YJL109C	UTP10	processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex
YGR280C	PXR1	35S primary transcript processing, snRNA processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	RNA binding -> RNA binding	nucleolus -> nucleus
\|YIL066C\|	RNR3	DNA replication -> cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ribonucleoside-diphosphate reductase activity -> oxidoreductase activity\, acting on CH2 groups	cytoplasm -> cytoplasm	RFX1, STB1
YOR294W	RRS1	ribosome biogenesis, rRNA processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism		nucleus -> nucleus	STB1
YOR310C	NOP58	rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription		small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	ABF1, SWI6
Main:		nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.71)	RNA binding (0.40)	nucleus (0.57)	STB1 (0.40)
Score:		0.48	0.10	0.33	0.100
P-value:		3.816E-04 (rRNA processing)	5.233E-01 (RNA binding)	8.698E-03 (small nucleolar ribonucleoprotein complex)	2.235E-02 (STB1)

ORF	SYMBOL	P	F	C	TF
\|YGR060W\|	ERG25	ergosterol biosynthesis -> alcohol metabolism, biosynthesis, lipid metabolism	C-4 methyl sterol oxidase activity -> C-4 methyl sterol oxidase activity	endoplasmic reticulum membrane, plasma membrane -> cytoplasm, plasma membrane, endomembrane system	HSF1, MAL13, MET4, NDD1, SWI5
YHR124W	NDT80	meiosis, transcription -> cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	transcription factor activity -> transcription factor activity	nuclear chromosome -> chromosome, nucleus	SUM1
YDR317W	NO SYMBOL				HAL9, RLM1
YBR115C	LYS2	lysine biosynthesis\, aminoadipic pathway -> amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis	aminoadipate-semialdehyde dehydrogenase activity -> aminoadipate-semialdehyde dehydrogenase activity	cytoplasm -> cytoplasm	DAL81, GCN4
YLR049C	NO SYMBOL				MBP1, SWI5
YDR218C	SPR28	cellular morphogenesis, cell wall organization and biogenesis -> cell organization and biogenesis	structural constituent of cytoskeleton -> structural constituent of cytoskeleton	septin ring (sensu Saccharomyces) -> site of polarized growth (sensu Fungi), cell cortex, cytoskeleton	YAP6
\|YGL046W\|	NO SYMBOL
YLR308W	CDA2	spore wall assembly (sensu Saccharomyces) -> sporulation	chitin deacetylase activity -> chitin deacetylase activity	chitosan layer of spore wall -> cell wall	REB1, SUM1
Main:		biosynthesis (0.40)	transcription factor activity (0.20)	cytoplasm (0.40)	SWI5 SUM1 (0.29)
Score:		0.10	0.00	0.10	0.095
P-value:		3.657E+00 (biosynthesis)	5.241E-01 (oxidoreductase activity)	4.615E+00 (cytoplasm)	1.215E-01 (SUM1)

ORF	SYMBOL	P	F	C	TF
YPL043W	NOP4	rRNA processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	RNA binding -> RNA binding	nucleolus -> nucleus
\|YMR310C\|	NO SYMBOL
YAL059W	ECM1	cell wall organization and biogenesis -> cell growth and/or maintenance			MOT3
YNL132W	KRE33
\|YML125C\|	NO SYMBOL				MAL13, MSN4, NDD1, RME1, SWI5
\|YOL022C\|	NO SYMBOL				MAC1, MOT3, RTS2
YNL209W	SSB2	protein biosynthesis -> biosynthesis, protein metabolism	chaperone activity, ATPase activity -> chaperone activity, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	polysome, cytoplasm -> cytoplasm, ribonucleoprotein complex	ABF1, RFX1
YFR001W	LOC1	ribosomal large subunit biogenesis -> cell growth and/or maintenance	mRNA binding -> RNA binding	nucleus -> nucleus	ARG80, GAL4, GTS1, HAP4, HIR1, LEU3, MSN2, MSN4, RCS1, RLM1, SWI4
YDR496C	PUF6				RFX1
YLR276C	DBP9	ribosomal large subunit assembly and maintenance, 35S primary transcript processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ATP dependent RNA helicase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleolus -> nucleus	MATa1, RCS1, RTG3, SWI5
\|YGL169W\|	SUA5	cell growth and/or maintenance -> cell growth and/or maintenance			ABF1
YLR002C	NOC3	DNA replication initiation, rRNA processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription	chromatin binding, protein binding -> DNA binding, protein binding	nucleus, nucleolus -> nucleus	HIR1, IXR1, RCS1
YBR267W	NO SYMBOL
YKL172W	EBP2	rRNA processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism		nucleolus -> nucleus	ABF1, FZF1, RFX1
\|YDR279W\|	RNH202				GCR2, MBP1, RIM101, RLM1, SWI6, THI2
YCR072C	NO SYMBOL				YFL044C
\|YHR128W\|	FUR1	pyrimidine salvage -> biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	uracil phosphoribosyltransferase activity -> transferase activity\, transferring glycosyl groups		CIN5
YMR290C	HAS1			nucleolus, nuclear membrane -> nucleus, endomembrane system	RAP1
YNL175C	NOP13		RNA binding -> RNA binding	nucleolus, nucleoplasm -> nucleus	INO2, INO4
YGR159C	NSR1	ribosomal small subunit assembly and maintenance, rRNA processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	single-stranded DNA binding, RNA binding -> DNA binding, RNA binding	nucleolus, nucleus -> nucleus
\|YOR078W\|	BUD21	processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	ABF1, MSS11, SIG1, SKO1
YPR010C	RPA135	transcription from Pol I promoter -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	DNA-directed RNA polymerase activity -> transferase activity\, transferring phosphorus-containing groups	DNA-directed RNA polymerase I complex -> nucleus	ROX1, SIG1
YKL014C	NO SYMBOL				ABF1
YHR089C	GAR1	rRNA modification, 35S primary transcript processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription	RNA binding -> RNA binding	nucleolus, small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	CBF1, FZF1
YPR144C	NOC4	ribosome biogenesis -> cell growth and/or maintenance		nucleus -> nucleus	HIR1
YIL122W	POG1	re-entry into mitotic cell cycle after pheromone arrest -> cell growth and/or maintenance, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus	specific RNA polymerase II transcription factor activity -> specific RNA polymerase II transcription factor activity	nucleus -> nucleus	ASH1, CIN5, NRG1, RLM1, SMP1, YAP6
YKL056C	NO SYMBOL
YDR184C	ATC1	response to stress, polar budding -> response to stress, asexual reproduction		nucleus -> nucleus	ARO80, GLN3, SIP4, SKO1
\|YPL266W\|	DIM1	rRNA modification, 35S primary transcript processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription	rRNA (adenine-N6\,N6-)-dimethyltransferase activity -> transferase activity\, transferring one-carbon groups	nucleolus -> nucleus	ARG81, STP2
YML093W	UTP14	processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex
YMR229C	RRP5	rRNA processing, processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	RNA binding, snoRNA binding -> RNA binding	nucleolus, nucleolus organizer complex -> nucleus	FHL1, RAP1
YNL110C	NOP15	ribosomal large subunit biogenesis -> cell growth and/or maintenance		nucleus, nucleolus -> nucleus
YMR131C	RRB1	ribosome biogenesis -> cell growth and/or maintenance		nucleolus -> nucleus	FZF1, MATa1, RGT1
YDR365C	NO SYMBOL				ABF1, MSS11, YJL206C
YGR145W	ENP2
\|YNR024W\|	NO SYMBOL
\|YBR104W\|	YMC2	transport -> cell growth and/or maintenance	transporter activity -> transporter activity	mitochondrial inner membrane -> cytoplasm, inner membrane	FKH1, FKH2
YGL171W	ROK1	35S primary transcript processing, mRNA splicing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ATP dependent RNA helicase activity, ATPase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleolus -> nucleus	RGT1
\|YGL016W\|	KAP122	protein-nucleus import, response to drug -> response to abiotic stimulus, protein metabolism, cell growth and/or maintenance	protein carrier activity -> protein binding	cytoplasm, nuclear pore -> cytoplasm, nucleus, integral to membrane, endomembrane system	MSN2
\|YGR272C\|	NO SYMBOL				REB1, STP2
YJL069C	UTP18				ABF1
YOR095C	RKI1	pentose-phosphate shunt -> coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism	ribose-5-phosphate isomerase activity -> intramolecular isomerase activity		FHL1, FKH2, RAP1
YLR197W	SIK1	rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription		small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex, nucleus, nucleolus -> nucleus, ribonucleoprotein complex	DAL81, HAL9
YMR049C	ERB1	rRNA processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism			RTG3
\|YJL033W\|	HCA4	35S primary transcript processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ATP dependent RNA helicase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleolus -> nucleus	HIR2, USV1
YNL075W	IMP4	rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription	rRNA primary transcript binding -> RNA binding	small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	USV1
YNL112W	DBP2		RNA helicase activity -> RNA binding	bud neck -> site of polarized growth (sensu Fungi)
\|YCR090C\|	NO SYMBOL
YDR101C	ARX1	ribosomal large subunit biogenesis -> cell growth and/or maintenance		nucleoplasm, cytoplasm -> nucleus, cytoplasm	IXR1, RFX1
YJL138C	TIF2	translational initiation, regulation of translational initiation -> biosynthesis, protein metabolism	translation initiation factor activity, RNA helicase activity -> translation factor activity\, nucleic acid binding, RNA binding	ribosome, cytoplasm -> cytoplasm, ribonucleoprotein complex	PHD1
YNL308C	KRI1	ribosome biogenesis -> cell growth and/or maintenance		nucleolus -> nucleus
YGR245C	SDA1	actin cytoskeleton organization and biogenesis, start control point of mitotic cell cycle -> cell growth and/or maintenance		nucleus -> nucleus
\|YCL059C\|	KRR1	ribosome biogenesis, rRNA processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism		nucleolus -> nucleus
YMR239C	RNT1	35S primary transcript processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ribonuclease III activity -> hydrolase activity\, acting on ester bonds, RNA binding	nucleolus -> nucleus
YNR053C	NOG2	mRNA splicing -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	GTPase activity -> purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleus, nucleolus, nucleoplasm -> nucleus, nucleoplasm	ABF1, AZF1
\|YNL292W\|	PUS4	tRNA modification -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	pseudouridylate synthase activity -> carbon-oxygen lyase activity	mitochondrion, nucleus -> cytoplasm, nucleus	RCS1
YJL109C	UTP10	processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex
YGR280C	PXR1	35S primary transcript processing, snRNA processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	RNA binding -> RNA binding	nucleolus -> nucleus
\|YDR161W\|	NO SYMBOL
YDR449C	UTP6	processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	FHL1, GAT3, HIR2, RAP1, RGM1, YAP5
YHR196W	UTP9	processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex, nucleolus, nucleus -> nucleus, ribonucleoprotein complex
\|YMR259C\|	NO SYMBOL				ARG80, GCR2, GTS1, HIR1, SRD1
\|YJL050W\|	MTR4	35S primary transcript processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ATP dependent RNA helicase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleolus -> nucleus
\|YDR399W\|	HPT1	purine nucleotide biosynthesis -> biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	hypoxanthine phosphoribosyltransferase activity -> transferase activity\, transferring glycosyl groups
\|YPR183W\|	DPM1	N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis -> lipid biosynthesis, biosynthesis, membrane lipid metabolism, protein metabolism, lipoprotein metabolism	transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity -> transferase activity\, transferring glycosyl groups	endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network -> cytoplasm, endomembrane system	SWI5
YJR070C	NO SYMBOL				GAT3, YAP5
YGL099W	LSG1	conjugation with cellular fusion, sporulation (sensu Saccharomyces), ribosome nucleus export -> conjugation, protein metabolism, cell growth and/or maintenance, sexual reproduction	GTPase activity -> purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	cytoplasm -> cytoplasm	PHO4
YGR162W	TIF4631	translational initiation -> biosynthesis, protein metabolism	translation initiation factor activity -> translation factor activity\, nucleic acid binding	ribosome -> cytoplasm, ribonucleoprotein complex	HSF1
YGR187C	HGH1				ABF1, HAP3, HIR1, RCS1, RTG1
\|YOR359W\|	VTS1	protein-vacuolar targeting -> protein metabolism, cell growth and/or maintenance	intracellular transporter activity -> transporter activity	cytosol -> cytoplasm	RAP1
YLR249W	YEF3	translational elongation -> biosynthesis, protein metabolism	translation elongation factor activity -> translation factor activity\, nucleic acid binding	ribosome -> cytoplasm, ribonucleoprotein complex	INO2, INO4
YJR002W	MPP10	rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription		small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex, nucleolus, nucleus -> nucleus, ribonucleoprotein complex
YOR310C	NOP58	rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription		small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	ABF1, SWI6
YHR169W	DBP8	35S primary transcript processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ATP dependent RNA helicase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleolus -> nucleus
YGL029W	CGR1	ribosome biogenesis, rRNA processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism		nucleolus -> nucleus
\|YOR381W\|	FRE3	iron-siderochrome transport, iron ion homeostasis -> cell growth and/or maintenance	ferric-chelate reductase activity -> oxidoreductase activity\, oxidizing metal ions	plasma membrane, integral to membrane -> plasma membrane, integral to membrane	CIN5, PDR1, YAP6
YOR272W	YTM1	chromosome organization and biogenesis (sensu Eukarya), ribosomal large subunit biogenesis -> cell growth and/or maintenance		nucleus, nucleolus -> nucleus	LEU3, PUT3, REB1
YCR016W	NO SYMBOL
\|YNR046W\|	NO SYMBOL				ABF1
YGL078C	DBP3	ribosomal large subunit assembly and maintenance, 35S primary transcript processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ATP dependent RNA helicase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleolus -> nucleus
YBR247C	ENP1	processing of 20S pre-rRNA, rRNA processing, cell growth and/or maintenance -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	nucleolus, nucleus -> nucleus
YMR014W	BUD22	bud site selection -> cell growth and/or maintenance		nucleus -> nucleus	CUP9, HAL9, HIR2, LEU3, NDD1, RLM1, ROX1, SMP1, YAP6
YJL148W	RPA34	transcription from Pol I promoter -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	DNA-directed RNA polymerase activity -> transferase activity\, transferring phosphorus-containing groups	DNA-directed RNA polymerase I complex, nucleus, nucleolus -> nucleus	AZF1, CHA4, CUP9, DAL81, DIG1, FZF1, GCR1, GCR2, GLN3, HAL9, HAP2, HAP3, HMS1, LEU3, MAC1, MBP1, MET31, MOT3, NDD1, PDR1, PHD1, REB1, RLM1, RME1, ROX1, RPH1, RTS2, SKN7, SWI5, YAP6, ZAP1
Main:		cell growth and/or maintenance (0.78)	RNA binding (0.55)	nucleus (0.82)	ABF1 (0.20)
Score:		0.73	0.33	0.73	0.101
P-value:		2.929E-31 (ribosome biogenesis)	2.998E-08 (snoRNA binding)	1.266E-32 (nucleolus)	8.516E-01 (LEU3)

ORF	SYMBOL	P	F	C	TF
YOL022C	NO SYMBOL				MAC1, MOT3, RTS2
YFR001W	LOC1	ribosomal large subunit biogenesis -> cell organization and biogenesis	mRNA binding -> RNA binding	nucleus -> nucleus	ARG80, GAL4, GTS1, HAP4, HIR1, LEU3, MSN2, MSN4, RCS1, RLM1, SWI4
YCR072C	NO SYMBOL				YFL044C
\|YHR128W\|	FUR1	pyrimidine salvage -> biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	uracil phosphoribosyltransferase activity -> transferase activity\, transferring glycosyl groups		CIN5
YMR290C	HAS1			nucleolus, nuclear membrane -> nucleus, endomembrane system	RAP1
\|YKL056C\|	NO SYMBOL
\|YPL266W\|	DIM1	rRNA modification, 35S primary transcript processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription	rRNA (adenine-N6\,N6-)-dimethyltransferase activity -> transferase activity\, transferring one-carbon groups	nucleolus -> nucleus	ARG81, STP2
YMR229C	RRP5	rRNA processing, processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	RNA binding, snoRNA binding -> RNA binding	nucleolus, nucleolus organizer complex -> nucleus	FHL1, RAP1
YMR131C	RRB1	ribosome biogenesis -> cell organization and biogenesis		nucleolus -> nucleus	FZF1, MATa1, RGT1
YJL069C	UTP18				ABF1
YOR095C	RKI1	pentose-phosphate shunt -> coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism	ribose-5-phosphate isomerase activity -> intramolecular isomerase activity		FHL1, FKH2, RAP1
\|YJL033W\|	HCA4	35S primary transcript processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ATP dependent RNA helicase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleolus -> nucleus	HIR2, USV1
YNL075W	IMP4	rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription	rRNA primary transcript binding -> RNA binding	small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	USV1
YMR239C	RNT1	35S primary transcript processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ribonuclease III activity -> hydrolase activity\, acting on ester bonds, RNA binding	nucleolus -> nucleus
YJL109C	UTP10	processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex
YHR196W	UTP9	processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex, nucleolus, nucleus -> nucleus, ribonucleoprotein complex
YMR259C	NO SYMBOL				ARG80, GCR2, GTS1, HIR1, SRD1
\|YPR183W\|	DPM1	N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis -> lipid biosynthesis, biosynthesis, membrane lipid metabolism, protein metabolism, lipoprotein metabolism	transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity -> transferase activity\, transferring glycosyl groups	endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network -> cytoplasm, endomembrane system	SWI5
YJR070C	NO SYMBOL				GAT3, YAP5
YLR249W	YEF3	translational elongation -> biosynthesis, protein metabolism	translation elongation factor activity -> translation factor activity\, nucleic acid binding	ribosome -> cytoplasm, ribonucleoprotein complex	INO2, INO4
YJR002W	MPP10	rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription		small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex, nucleolus, nucleus -> nucleus, ribonucleoprotein complex
\|YHR169W\|	DBP8	35S primary transcript processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ATP dependent RNA helicase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleolus -> nucleus
YGL029W	CGR1	ribosome biogenesis, rRNA processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism		nucleolus -> nucleus
YOR381W	FRE3	iron-siderochrome transport, iron ion homeostasis -> transport, cell homeostasis	ferric-chelate reductase activity -> oxidoreductase activity\, oxidizing metal ions	plasma membrane, integral to membrane -> plasma membrane, integral to membrane	CIN5, PDR1, YAP6
Main:		cell organization and biogenesis (0.71)	RNA binding (0.57)	nucleus (0.81)	RAP1 (0.18)
Score:		0.58	0.32	0.70	0.044
P-value:		1.939E-10 (ribosome biogenesis)	2.350E-03 (snoRNA binding)	7.819E-11 (nucleolus)	1.000E+00

ORF	SYMBOL	P	F	C	TF
YHR085W	IPI1	rRNA processing -> cytoplasm organization and biogenesis, RNA metabolism, transcription			FZF1
YMR253C	NO SYMBOL				MCM1
YLR229C	CDC42	exocytosis, apical bud growth, isotropic bud growth, pseudohyphal growth, invasive growth, Rho protein signal transduction, signal transduction during conjugation with cellular fusion, establishment of cell polarity (sensu Saccharomyces) -> secretory pathway, budding, growth pattern, cellular morphogenesis, intracellular signaling cascade, cell surface receptor linked signal transduction, conjugation with cellular fusion, cytoplasm organization and biogenesis, perception of abiotic stimulus, sensory perception, vesicle-mediated transport	Rho small monomeric GTPase activity, signal transducer activity -> Rho small monomeric GTPase activity, signal transducer activity	soluble fraction, plasma membrane, bud tip, bud neck, shmoo tip -> soluble fraction, plasma membrane, bud tip, bud neck, shmoo tip	ABF1, FZF1, INO2, RTS2
YOL132W	GAS4			cell wall (sensu Fungi) -> cell wall (sensu Fungi)
YDR297W	SUR2	sphingolipid metabolism, sphingolipid biosynthesis -> membrane lipid metabolism, lipid biosynthesis	sphingosine hydroxylase activity -> sphingosine hydroxylase activity	endoplasmic reticulum -> endoplasmic reticulum	CBF1, MTH1
\|YPR185W\|	APG13	protein-vacuolar targeting, autophagy -> cytoplasm organization and biogenesis, autophagy, intracellular transport, protein metabolism, protein transport	protein binding -> protein binding	extrinsic to membrane -> extrinsic to membrane	MET4, SWI6
Main:		cytoplasm organization and biogenesis (0.75)	protein binding (0.33)	endoplasmic reticulum (0.25)	FZF1 (0.40)
Score:		0.50	0.00	0.00	0.100
P-value:		7.326E-01 (cytoplasm organization and biogenesis)	2.356E+00 (binding)	1.742E+00 (membrane)	4.289E-02 (FZF1)

ORF	SYMBOL	P	F	C	TF
YPL090C	RPS6A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	FHL1, GAT3, INO4, RAP1, YAP5
\|YDR450W\|	RPS18A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	FHL1, GAT3, HIR2, RAP1, RGM1, YAP5
YGR254W	ENO1	gluconeogenesis, glycolysis -> alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism	phosphopyruvate hydratase activity -> carbon-oxygen lyase activity	phosphopyruvate hydratase complex, cytoplasm -> cytoplasm	FKH2, MSN4, PDR1, SWI5, YAP5
YLR061W	RPL22A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	BAS1, FHL1, HIR1, PDR1, RAP1, RCS1, RME1, ZAP1
YGR085C	RPL11B	protein biosynthesis, ribosomal large subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, MIG1
\|YPL180W\|	BIT89	glycerol metabolism -> alcohol metabolism, glycerol ether metabolism, lipid metabolism			REB1, RGT1, SIG1
YGL030W	RPL30	protein biosynthesis, rRNA processing, mRNA splicing, regulation of translation -> cell organization and biogenesis, biosynthesis, transcription, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya), cytoplasm -> cytoplasm, ribonucleoprotein complex	FHL1, GAT3, RAP1, SFP1
YNL069C	RPL16B	protein biosynthesis -> biosynthesis, protein metabolism	RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, GAT3, PDR1, RAP1, RGM1, YAP5
YOL120C	RPL18A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, MAL13, RAP1, YAP5
\|YJR139C\|	HOM6	homoserine biosynthesis, methionine metabolism, threonine metabolism -> amine metabolism, sulfur metabolism, biosynthesis, amino acid and derivative metabolism, organic acid metabolism	homoserine dehydrogenase activity -> oxidoreductase activity\, acting on CH-OH group of donors		HMS1, RAP1
\|YHL038C\|	CBP2	RNA splicing -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	pre-mRNA splicing factor activity -> RNA binding	mitochondrion -> cytoplasm	RAP1
YGL147C	RPL9A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, MBP1, RAP1, SWI4
\|YLR146C\|	SPE4	pantothenate biosynthesis, spermine biosynthesis -> biosynthesis, amine metabolism, coenzymes and prosthetic group metabolism, amino acid and derivative metabolism, secondary metabolism	spermine synthase activity -> transferase activity\, transferring alkyl or aryl (other than methyl) groups
YGR214W	RPS0A	protein biosynthesis, ribosomal small subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	FHL1, RAP1
YDL130W	RPP1B	protein biosynthesis, translational elongation -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, GAL4, RAP1, RFX1
YLR344W	RPL26A	protein biosynthesis -> biosynthesis, protein metabolism	RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, RAP1
YIL018W	RPL2B	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, GAT3, PDR1, RAP1, RGM1, SWI5, YAP5
YKL006W	RPL14A	protein biosynthesis -> biosynthesis, protein metabolism	RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, GAT3, GRF10(Pho2), GTS1, RAP1
YKL152C	GPM1	gluconeogenesis, glycolysis -> alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism	phosphoglycerate mutase activity -> intramolecular transferase activity	cytosol -> cytoplasm	GCR1, GCR2, HSF1, RAP1
\|YKL033W\|	NO SYMBOL				RPH1
YBR117C	TKL2	pentose-phosphate shunt -> coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism	transketolase activity -> transferase activity\, transferring aldehyde or ketonic groups		FHL1, RAP1
Main:		biosynthesis (0.85)	structural constituent of ribosome (0.68)	cytoplasm (1.00)	RAP1 (0.80)
Score:		0.75	0.47	1.00	0.732
P-value:		2.321E-07 (biosynthesis)	4.470E-11 (structural constituent of ribosome)	1.734E-12 (cytosolic ribosome (sensu Eukarya))	1.498E-16 (FHL1)

ORF	SYMBOL	P	F	C	TF
YOR213C	SAS5	chromatin silencing at telomere -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription	acetyltransferase activity -> acetyltransferase activity	nuclear chromosome\, telomeric region, nuclear chromatin -> chromosome, nuclear chromosome	GRF10(Pho2), SUM1
YGR254W	ENO1	gluconeogenesis, glycolysis -> alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism	phosphopyruvate hydratase activity -> phosphopyruvate hydratase activity	phosphopyruvate hydratase complex, cytoplasm -> cytoplasm	FKH2, MSN4, PDR1, SWI5, YAP5
YLR441C	RPS1A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	FHL1, GAT3, RAP1, YAP5
YNL096C	RPS7B	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	FHL1, GAT3, RAP1, SFP1
YDR406W	PDR15	transport -> transport	ATP-binding cassette (ABC) transporter activity -> ATP-binding cassette (ABC) transporter activity	integral to membrane -> integral to membrane
YPR080W	TEF1	translational elongation -> biosynthesis, protein metabolism	translation elongation factor activity -> translation elongation factor activity	ribosome -> cytoplasm, ribonucleoprotein complex	FHL1, PDR1, RAP1, YAP5
Main:		biosynthesis (0.67)	structural constituent of ribosome (0.33)	cytoplasm (0.67)	RAP1 FHL1 YAP5 (0.60)
Score:		0.40	0.07	0.40	0.500
P-value:		1.961E-01 (biosynthesis)	2.565E-01 (structural constituent of ribosome)	5.038E-02 (cytosolic small ribosomal subunit (sensu Eukarya))	8.067E-04 (YAP5)

ORF	SYMBOL	P	F	C	TF
YNL196C	NO SYMBOL
YDR285W	ZIP1	meiosis, synapsis -> cell proliferation	binding -> binding	synaptonemal complex -> chromosome, nucleus	ABF1, FKH1, GCR2, GLN3, GTS1, RIM101, RTG1, SWI6
YHL024W	RIM4	sporulation, meiosis, premeiotic DNA synthesis, meiotic recombination -> sporulation, M phase, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, cell proliferation	binding -> binding	cytoplasm -> cytoplasm	FKH2, PHD1
YPR007C	SPO69	meiosis, sister chromatid cohesion -> cell proliferation	binding -> binding	condensed nuclear chromosome\, pericentric region, nuclear cohesin complex -> chromosome, nuclear chromosome	MCM1
YDR180W	SCC2	mitotic sister chromatid cohesion -> cell proliferation, cell cycle	protein kinase activity -> protein kinase activity	nuclear cohesin complex -> chromosome, nucleus	GLN3, MSN4, ROX1
\|YMR280C\|	CAT8	gluconeogenesis, positive regulation of transcription from Pol II promoter -> alcohol metabolism, monosaccharide metabolism, carbohydrate metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, biosynthesis, energy pathways	specific RNA polymerase II transcription factor activity -> specific RNA polymerase II transcription factor activity	nucleus -> nucleus	ABF1, REB1
\|YDR091C\|	RLI1		binding -> binding
Main:		cell proliferation (0.80)	binding (0.67)	nucleus (0.60)	ABF1 GLN3 (0.40)
Score:		0.70	0.40	0.50	0.200
P-value:		4.464E-03 (sister chromatid cohesion)	3.930E-01 (binding)	1.718E-03 (condensed chromosome)	4.976E-02 (GLN3)

ORF	SYMBOL	P	F	C	TF
\|YOL075C\|	NO SYMBOL				CRZ1, DAL82, SIP4
YHR128W	FUR1	pyrimidine salvage -> biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	uracil phosphoribosyltransferase activity -> transferase activity\, transferring glycosyl groups		CIN5
YML093W	UTP14	processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex
YGR280C	PXR1	35S primary transcript processing, snRNA processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	RNA binding -> RNA binding	nucleolus -> nucleus
YJR070C	NO SYMBOL				GAT3, YAP5
YGL099W	LSG1	conjugation with cellular fusion, sporulation (sensu Saccharomyces), ribosome nucleus export -> conjugation, sporulation, cell organization and biogenesis, protein metabolism, transport, sexual reproduction	GTPase activity -> purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	cytoplasm -> cytoplasm	PHO4
YDR361C	BCP1				ABF1, ARO80, GLN3, HAP5, IXR1, YAP1
YGR191W	HIP1	manganese ion transport, histidine transport -> transport, organic acid transport	histidine transporter activity -> carboxylic acid transporter activity	plasma membrane -> plasma membrane	GLN3, HAP3, HIR2, MBP1, MCM1, REB1, YAP1
\|YGR178C\|	PBP1	mRNA polyadenylation -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism		cytoplasm, nucleus -> cytoplasm, nucleus	CIN5, DOT6, MSS11
Main:		nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.67)	RNA binding (0.40)	nucleus (0.60)	CIN5 YAP1 GLN3 (0.29)
Score:		0.60	0.10	0.40	0.095
P-value:		6.921E-02 (ribosome biogenesis)	8.159E-01 (RNA binding)	3.071E-01 (nucleolus)	1.198E-01 (GLN3)

ORF	SYMBOL	P	F	C	TF
YJL160C	NO SYMBOL				ACE2, HIR2, MCM1, SWI5
YPR122W	AXL1	axial budding, bud site selection, conjugation with cellular fusion, peptide pheromone maturation -> asexual reproduction, conjugation, protein metabolism, cell proliferation, cell organization and biogenesis, sexual reproduction	metalloendopeptidase activity -> endopeptidase activity, metallopeptidase activity	integral to membrane, bud neck, shmoo tip -> integral to membrane, site of polarized growth (sensu Fungi)	CIN5
\|YHR207C\|	SET5				LEU3, PHO4
\|YGR060W\|	ERG25	ergosterol biosynthesis -> alcohol metabolism, biosynthesis, lipid metabolism	C-4 methyl sterol oxidase activity -> C-4 methyl sterol oxidase activity	endoplasmic reticulum membrane, plasma membrane -> cytoplasm, plasma membrane, endomembrane system	HSF1, MAL13, MET4, NDD1, SWI5
YNR034W	SOL1	tRNA processing -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism			YFL044C
YNL034W	NO SYMBOL				MAC1, MET4, NDD1, RME1
YFR023W	PES4	DNA dependent DNA replication -> cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism			DIG1, FKH1, FKH2, GLN3, HAP3, MCM1, MSN2, RIM101, RLM1, RTG3, STE12, SUM1, THI2, YAP1
YMR125W	STO1	mRNA splicing -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	mRNA binding -> mRNA binding	commitment complex, snRNA cap binding complex -> nucleus, cytoplasm, ribonucleoprotein complex	ABF1, FZF1, HAP3, MET31, RTG1, SRD1, SUM1, YAP6, ZAP1
YOL132W	GAS4			cell wall (sensu Fungi) -> cell wall
YGL116W	CDC20	mitotic spindle elongation, ubiquitin-dependent protein catabolism, mitotic metaphase/anaphase transition, mitotic chromosome segregation, cyclin catabolism -> cell organization and biogenesis, catabolism, cell proliferation, cell cycle, protein metabolism	enzyme activator activity -> enzyme activator activity	anaphase-promoting complex -> nucleus, ubiquitin ligase complex	DIG1, FKH2, INO2, INO4, IXR1, MCM1, NDD1
\|YOR388C\|	FDH1	formate catabolism, NADH regeneration -> catabolism, coenzymes and prosthetic group metabolism, one-carbon compound metabolism, vitamin metabolism, organic acid metabolism	formate dehydrogenase activity -> oxidoreductase activity\, acting on the aldehyde or oxo group of donors\, NAD or NADP as acceptor	cytosol -> cytoplasm	MCM1, YJL206C
YBR115C	LYS2	lysine biosynthesis\, aminoadipic pathway -> amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis	aminoadipate-semialdehyde dehydrogenase activity -> oxidoreductase activity\, acting on the aldehyde or oxo group of donors\, NAD or NADP as acceptor	cytoplasm -> cytoplasm	DAL81, GCN4
YDR438W	NO SYMBOL				CBF1
\|YGL189C\|	RPS26A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	FHL1, GAT3, PDR1, RAP1, RGM1, YAP5
YDR218C	SPR28	cellular morphogenesis, cell wall organization and biogenesis -> cell organization and biogenesis	structural constituent of cytoskeleton -> structural constituent of cytoskeleton	septin ring (sensu Saccharomyces) -> site of polarized growth (sensu Fungi), cell cortex, cytoskeleton	YAP6
\|YGL121C\|	GPG1	signal transduction -> signal transduction	signal transducer activity -> signal transducer activity		CHA4
YOR214C	NO SYMBOL				BAS1
\|YMR280C\|	CAT8	gluconeogenesis, positive regulation of transcription from Pol II promoter -> alcohol metabolism, monosaccharide metabolism, carbohydrate metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, biosynthesis, energy pathways	specific RNA polymerase II transcription factor activity -> specific RNA polymerase II transcription factor activity	nucleus -> nucleus	ABF1, REB1
YMR001C	CDC5	DNA dependent DNA replication, protein amino acid phosphorylation -> phosphorus metabolism, cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism	protein serine/threonine kinase activity -> phosphotransferase activity\, alcohol group as acceptor	nucleus, spindle pole, bud neck -> nucleus, cytoplasm, site of polarized growth (sensu Fungi)	NDD1, REB1, SWI6
Main:		nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.38)	oxidoreductase activity\, acting on the aldehyde or oxo group of donors\, NAD or NADP as acceptor (0.18)	cytoplasm (0.55)	NDD1 MCM1 (0.22)
Score:		0.36	0.02	0.42	0.111
P-value:		1.825E+00 (DNA dependent DNA replication)	4.899E-02 (oxidoreductase activity\, acting on the aldehyde or oxo group of donors\, NAD or NADP as acceptor)	1.555E-01 (bud neck)	7.065E-02 (NDD1)

ORF	SYMBOL	P	F	C	TF
YGR060W	ERG25	ergosterol biosynthesis -> alcohol metabolism, biosynthesis, lipid metabolism	C-4 methyl sterol oxidase activity -> C-4 methyl sterol oxidase activity	endoplasmic reticulum membrane, plasma membrane -> cytoplasm, plasma membrane, endomembrane system	HSF1, MAL13, MET4, NDD1, SWI5
YOL038W	PRE6	ubiquitin-dependent protein catabolism -> catabolism, protein metabolism	endopeptidase activity -> peptidase activity	proteasome core complex (sensu Eukarya) -> cytoplasm, nucleus
\|YGR184C\|	UBR1	protein polyubiquitination, protein monoubiquitination -> catabolism, protein metabolism	ubiquitin-protein ligase activity -> ligase activity\, forming carbon-nitrogen bonds	proteasome complex (sensu Eukarya) -> cytoplasm, nucleus	HMS1, REB1, RIM101
YDL126C	CDC48	ubiquitin-dependent protein catabolism, nonselective vesicle fusion, cell cycle, apoptosis, protein transport, ER-associated protein catabolism -> cell proliferation, cell death, macromolecule catabolism, transport, protein metabolism	ATPase activity -> purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleus, microsome, endoplasmic reticulum, cytosol -> nucleus, membrane fraction, cytoplasm	DAL82, MAL33, SWI4
\|YBL022C\|	PIM1	proteolysis and peptidolysis, response to heat -> catabolism, response to abiotic stimulus, protein metabolism	ATP-dependent peptidase activity -> peptidase activity	mitochondrial matrix -> cytoplasm	RAP1
YDR212W	TCP1	protein folding, cytoskeleton organization and biogenesis -> protein metabolism, cell organization and biogenesis	chaperone activity -> chaperone activity	cytoplasm, cytoskeleton -> cytoplasm
YKL054C	DEF1	response to DNA damage, ubiquitin-dependent protein catabolism -> response to biotic stimulus, catabolism, protein metabolism		nucleus -> nucleus
Main:		protein metabolism (0.86)	peptidase activity (0.33)	cytoplasm (0.86)	SWI4 (0.25)
Score:		0.71	0.07	0.86	0.000
P-value:		1.376E-05 (proteolysis and peptidolysis)	8.873E-02 (peptidase activity)	7.428E-03 (endoplasmic reticulum)	4.110E-01 (MAL33)

ORF	SYMBOL	P	F	C	TF
YNL097C	PHO23	chromatin modification -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism		nucleus -> nucleus	MAC1
YGR060W	ERG25	ergosterol biosynthesis -> alcohol metabolism, biosynthesis, lipid metabolism	C-4 methyl sterol oxidase activity -> C-4 methyl sterol oxidase activity	endoplasmic reticulum membrane, plasma membrane -> cytoplasm, plasma membrane, endomembrane system	HSF1, MAL13, MET4, NDD1, SWI5
YIL075C	RPN2	ubiquitin-dependent protein catabolism -> catabolism, protein metabolism	receptor activity, endopeptidase activity -> receptor activity, endopeptidase activity	proteasome regulatory particle (sensu Eukarya) -> cytoplasm, nucleus	MSS11, REB1, SFL1
\|YJL045W\|	NO SYMBOL				MBP1, ROX1
YPL190C	NAB3	regulation of transcription from Pol II promoter -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	poly(A) binding -> poly(A) binding	nucleoplasm -> nucleus	RFX1
YNL012W	SPO1	meiosis -> cell proliferation	phospholipase activity -> phospholipase activity	nucleus -> nucleus	ARO80, SRD1
YGR253C	PUP2	ubiquitin-dependent protein catabolism, response to stress, sporulation (sensu Saccharomyces) -> catabolism, response to stress, sporulation, protein metabolism	endopeptidase activity -> endopeptidase activity	proteasome core complex (sensu Eukarya) -> cytoplasm, nucleus	ABF1, HIR2, PHO4
\|YNL241C\|	ZWF1	pentose-phosphate shunt -> coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism	glucose-6-phosphate 1-dehydrogenase activity -> glucose-6-phosphate 1-dehydrogenase activity	cytoplasm -> cytoplasm	ACE2, ADR1, FKH2, HIR1, IME4, MBP1, NDD1, PHO4, RCS1, SFP1, SKN7, SWI5
YER021W	RPN3	ubiquitin-dependent protein catabolism -> catabolism, protein metabolism	endopeptidase activity -> endopeptidase activity	proteasome regulatory particle (sensu Eukarya) -> cytoplasm, nucleus
YGL201C	MCM6	DNA unwinding, DNA replication initiation -> cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	chromatin binding, ATP dependent DNA helicase activity -> chromatin binding, ATP dependent DNA helicase activity	cytoplasm, nucleus, pre-replicative complex -> cytoplasm, nucleus	MCM1
\|YKL054C\|	DEF1	response to DNA damage, ubiquitin-dependent protein catabolism -> response to biotic stimulus, catabolism, protein metabolism		nucleus -> nucleus
YOR052C	NO SYMBOL
Main:		catabolism (0.50)	endopeptidase activity (0.38)	nucleus (0.80)	NDD1 PHO4 SWI5 MBP1 (0.22)
Score:		0.33	0.11	0.82	0.083
P-value:		5.589E-03 (ubiquitin-dependent protein catabolism)	2.690E-03 (endopeptidase activity)	3.129E-03 (proteasome complex (sensu Eukarya))	7.289E-01 (PHO4)

ORF	SYMBOL	P	F	C	TF
YLR355C	ILV5	branched chain family amino acid biosynthesis, mitochondrial genome maintenance -> amino acid biosynthesis, mitochondrion organization and biogenesis, branched chain family amino acid metabolism	ketol-acid reductoisomerase activity -> oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor	mitochondrion -> cytoplasm	GCN4, MET4
YOR108W	LEU9	leucine biosynthesis -> amino acid biosynthesis, branched chain family amino acid metabolism	2-isopropylmalate synthase activity -> oxo-acid-lyase activity	mitochondrion -> cytoplasm	AZF1, GCN4, LEU3
\|YDL194W\|	SNF3	signal transduction, response to glucose stimulus -> signal transduction, response to glucose stimulus	receptor activity, glucose binding, glucose transporter activity -> receptor activity, monosaccharide binding, hexose transporter activity	plasma membrane -> plasma membrane
YGL009C	LEU1	leucine biosynthesis -> amino acid biosynthesis, branched chain family amino acid metabolism	3-isopropylmalate dehydratase activity -> hydro-lyase activity	cytosol -> cytoplasm	LEU3
YDR158W	HOM2	homoserine biosynthesis, threonine metabolism, methionine metabolism -> amino acid biosynthesis, aspartate family amino acid metabolism, homoserine metabolism, serine family amino acid metabolism, sulfur amino acid metabolism	aspartate-semialdehyde dehydrogenase activity -> oxidoreductase activity\, acting on the aldehyde or oxo group of donors\, NAD or NADP as acceptor		ACE2, HSF1, NDD1, REB1, SKN7, SWI5
YJR016C	ILV3	branched chain family amino acid biosynthesis -> amino acid biosynthesis, branched chain family amino acid metabolism	dihydroxy-acid dehydratase activity -> hydro-lyase activity	mitochondrion -> cytoplasm
Main:		amino acid biosynthesis (0.83)	hydro-lyase activity (0.33)	cytoplasm (0.80)	LEU3 GCN4 (0.50)
Score:		0.67	0.07	0.60	0.333
P-value:		6.193E-08 (branched chain family amino acid biosynthesis)	4.845E-03 (lyase activity)	1.878E-01 (mitochondrion)	1.596E-02 (LEU3)