Binding site rules

SFF(1) AND mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YGR280C) OR SimExpr(other) : 7 3

EXPR: (0.134) SFF (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.004) SCB (P < 0.000)

ORF SYMBOL P F C TF
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
cytoplasm organization and biogenesis, RNA metabolism, transcription RNA binding ->
RNA binding nucleolus ->
nucleus
|YJL138C| TIF2 translational initiation, regulation of translational initiation ->
macromolecule biosynthesis, protein metabolism translation initiation factor activity, RNA helicase activity ->
translation factor activity\, nucleic acid binding, RNA binding ribosome, cytoplasm ->
cytoplasm, ribonucleoprotein complex PHD1
|YMR259C| NO SYMBOL ARG80, GCR2, GTS1, HIR1, SRD1
YHR052W CIC1 protein catabolism ->
macromolecule catabolism, protein metabolism protein binding\, bridging ->
protein binding\, bridging nucleolus, proteasome complex (sensu Eukarya) ->
nucleus, cytoplasm HAP4, MATa1
YOR078W BUD21 processing of 20S pre-rRNA ->
cytoplasm organization and biogenesis, RNA metabolism, transcription snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex ABF1, MSS11, SIG1, SKO1
YBR104W YMC2 transport ->
transport transporter activity ->
transporter activity mitochondrial inner membrane ->
cytoplasm, inner membrane FKH1, FKH2
YJL109C UTP10 processing of 20S pre-rRNA ->
cytoplasm organization and biogenesis, RNA metabolism, transcription snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
YJL069C UTP18 ABF1
YCL059C KRR1 ribosome biogenesis, rRNA processing ->
cytoplasm organization and biogenesis, RNA metabolism, transcription nucleolus ->
nucleus
|YLR249W| YEF3 translational elongation ->
macromolecule biosynthesis, protein metabolism translation elongation factor activity ->
translation factor activity\, nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex INO2, INO4
Main: RNA metabolism (0.50) RNA binding (0.57) nucleus (0.62) ABF1 (0.29)
Score: 0.32 0.33 0.71 0.048
P-value: 3.912E-03 (rRNA processing) 1.827E-02 (snoRNA binding) 2.304E-04 (nucleolus) 1.000E+00

LYS14(1) AND mRRPE(1) AND PAC(1) => SimExpr(YGR280C) OR SimExpr(other) : 7 2

EXPR: (0.126) LYS14 (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.002)

ORF SYMBOL P F C TF
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding nucleolus ->
nucleus
YML093W UTP14 processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
|YMR259C| NO SYMBOL ARG80, GCR2, GTS1, HIR1, SRD1
YHR052W CIC1 protein catabolism ->
catabolism, protein metabolism protein binding\, bridging ->
protein binding\, bridging nucleolus, proteasome complex (sensu Eukarya) ->
nucleus, cytoplasm HAP4, MATa1
YJR070C NO SYMBOL GAT3, YAP5
YNL110C NOP15 ribosomal large subunit biogenesis ->
cell organization and biogenesis nucleus, nucleolus ->
nucleus
|YHR128W| FUR1 pyrimidine salvage ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism uracil phosphoribosyltransferase activity ->
transferase activity\, transferring glycosyl groups CIN5
YMR290C HAS1 nucleolus, nuclear membrane ->
nucleus, endomembrane system RAP1
YGL099W LSG1 conjugation with cellular fusion, sporulation (sensu Saccharomyces), ribosome nucleus export ->
conjugation, sporulation, cell organization and biogenesis, protein metabolism, transport, sexual reproduction GTPase activity ->
purine nucleotide binding, hydrolase activity\, acting on acid anhydrides cytoplasm ->
cytoplasm PHO4
Main: cell organization and biogenesis (0.67) RNA binding (0.40) nucleus (0.83) GCR2 (0.17)
Score: 0.60 0.10 0.73 0.000
P-value: 5.396E-03 (ribosome biogenesis) 9.488E-01 (RNA binding) 8.333E-05 (nucleolus) 9.462E-01 (MATa1)

STRE'(1) AND Gcr1(1) => SimExpr(YJL052W) : 5

EXPR: (0.108) STRE' (P < 0.000) Gcr1 (P < 0.000)

ORF SYMBOL P F C TF
YER177W BMH1 pseudohyphal growth, sporulation (sensu Saccharomyces), RAS protein signal transduction, activation of MAPK (pseudohyphal growth), glycogen metabolism ->
cell organization and biogenesis, sporulation, carbohydrate metabolism, signal transduction, energy derivation by oxidation of organic compounds DNA binding ->
DNA binding nucleus ->
nucleus ACE2, GCR1, MBP1, NDD1, SWI4, SWI5
YGR254W ENO1 gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism phosphopyruvate hydratase activity ->
hydro-lyase activity phosphopyruvate hydratase complex, cytoplasm ->
cytoplasm FKH2, MSN4, PDR1, SWI5, YAP5
YNL241C ZWF1 pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism glucose-6-phosphate 1-dehydrogenase activity ->
oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor cytoplasm ->
cytoplasm ACE2, ADR1, FKH2, HIR1, IME4, MBP1, NDD1, PHO4, RCS1, SFP1, SKN7, SWI5
YJL052W TDH1 gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) activity ->
oxidoreductase activity\, acting on the aldehyde or oxo group of donors\, NAD or NADP as acceptor cytosol, lipid particle, cell wall ->
cytoplasm, cell wall MAC1
YOR374W ALD4 ethanol metabolism ->
alcohol metabolism aldehyde dehydrogenase (NAD+) activity ->
oxidoreductase activity\, acting on the aldehyde or oxo group of donors\, NAD or NADP as acceptor mitochondrion ->
cytoplasm RAP1
Main: alcohol metabolism (0.80) oxidoreductase activity\, acting on the aldehyde or oxo group of donors\, NAD or NADP as acceptor (0.40) cytoplasm (0.80) SWI5 (0.60)
Score: 0.90 0.10 0.60 0.300
P-value: 1.748E-04 (monosaccharide catabolism) 3.111E-03 (oxidoreductase activity\, acting on the aldehyde or oxo group of donors\, NAD or NADP as acceptor) 5.952E-01 (cytosol) 2.493E-03 (SWI5)

MCB(1) AND PAC(1) => SimExpr(YLR049C) OR SimExpr(other) : 5 2

EXPR: (0.125) MCB (P < 0.001) PAC (P < 0.000)

ORF SYMBOL P F C TF
|YIL026C| IRR1 mitotic sister chromatid cohesion, colony morphology, germination (sensu Saccharomyces), cytogamy ->
cell organization and biogenesis, sporulation, plasma membrane fusion, sporulation (sensu Fungi), cell proliferation, conjugation, sexual reproduction protein binding ->
protein binding nuclear cohesin complex ->
chromosome, nucleus ABF1, MAL33, MBP1, SWI6
YPR144C NOC4 ribosome biogenesis ->
cell organization and biogenesis nucleus ->
nucleus HIR1
YLR049C NO SYMBOL MBP1, SWI5
YIL066C RNR3 DNA replication ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ribonucleoside-diphosphate reductase activity ->
ribonucleoside-diphosphate reductase activity cytoplasm ->
cytoplasm RFX1, STB1
YDR279W RNH202 GCR2, MBP1, RIM101, RLM1, SWI6, THI2
YOR284W HUA2 RFX1, YAP6
|YJR055W| HIT1 aerobic respiration ->
energy pathways STP2
Main: cell organization and biogenesis (0.50) ribonucleoside-diphosphate reductase activity (0.50) nucleus (0.67) MBP1 (0.43)
Score: 0.33 0.00 0.33 0.190
P-value: 5.867E-01 (DNA replication and chromosome cycle) 2.000E+00 3.799E+00 (nucleus) 1.050E-02 (MBP1)

ALPHA1'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YOR272W) OR SimExpr(other) : 36 12

EXPR: (0.133) ALPHA1' (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.001)

CSRE(1) AND mRRPE(1) AND PAC(1) => SimExpr(YGR159C) : 5

EXPR: (0.099) mRRPE (P < 0.000) PAC (P < 0.000) CSRE (P < 0.000)

ORF SYMBOL P F C TF
YOR310C NOP58 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex ABF1, SWI6
YGR245C SDA1 actin cytoskeleton organization and biogenesis, start control point of mitotic cell cycle ->
cell organization and biogenesis, cell proliferation nucleus ->
nucleus
YDR399W HPT1 purine nucleotide biosynthesis ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism hypoxanthine phosphoribosyltransferase activity ->
hypoxanthine phosphoribosyltransferase activity
YPR010C RPA135 transcription from Pol I promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DNA-directed RNA polymerase activity ->
DNA-directed RNA polymerase activity DNA-directed RNA polymerase I complex ->
nucleus ROX1, SIG1
YGR159C NSR1 ribosomal small subunit assembly and maintenance, rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism single-stranded DNA binding, RNA binding ->
single-stranded DNA binding, RNA binding nucleolus, nucleus ->
nucleus
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.80) RNA binding (0.33) nucleus (1.00) ABF1 (0.50)
Score: 0.80 0.00 1.00 0.000
P-value: 7.627E-03 (transcription from Pol I promoter) 7.516E-01 (transferase activity) 3.882E-03 (nucleolus) 2.427E-01 (SIG1)

ECB(1) AND MCB(1) => SimExpr(YML027W) OR SimExpr(other) : 5 2

EXPR: (0.117) ECB (P < 0.000) MCB (P < 0.024)

ORF SYMBOL P F C TF
YCL024W KCC4 septin checkpoint, protein amino acid phosphorylation, bud growth, axial budding, septin ring assembly ->
cell cycle, phosphate metabolism, budding, septin ring assembly, protein modification protein kinase activity ->
protein kinase activity bud neck ->
bud neck ASH1, CIN5, DAL81, HSF1, MET4, PHD1, RAP1, STP1, STP2
|YMR102C| NO SYMBOL
YNR028W CPR8 peptidyl-prolyl cis-trans isomerase activity ->
peptidyl-prolyl cis-trans isomerase activity ASH1, DIG1, MCM1
YCR065W HCM1 spindle assembly, transcription initiation from Pol II promoter ->
cytoplasm organization and biogenesis, cell cycle, transcription specific RNA polymerase II transcription factor activity ->
specific RNA polymerase II transcription factor activity nucleus ->
nucleus ASH1, HSF1, MBP1, NDD1, PHD1, ROX1, STB1, SWI4
YDR507C GIN4 septin checkpoint, protein amino acid phosphorylation, bud growth, axial budding, septin ring assembly ->
cell cycle, phosphate metabolism, budding, septin ring assembly, protein modification protein kinase activity ->
protein kinase activity bud neck ->
bud neck GRF10(Pho2), GTS1, MBP1, MCM1, SWI4, SWI6
|YGR189C| CRH1 cell wall, incipient bud site ->
cell wall, incipient bud site GRF10(Pho2), MBP1, RLM1, STE12, SWI4, SWI5
YML027W YOX1 negative regulation of transcription from Pol II promoter\, mitotic, regulation of mitotic cell cycle ->
regulation of transcription, M phase, transcription, cell cycle specific transcriptional repressor activity, DNA binding ->
specific transcriptional repressor activity, DNA binding nucleus ->
nucleus MBP1, SWI4, SWI6
Main: cell cycle (1.00) protein kinase activity (0.40) nucleus (0.40) SWI4 MBP1 (0.67)
Score: 1.00 0.10 0.20 0.667
P-value: 3.093E-04 (septin checkpoint) 3.615E-01 (protein kinase activity) 1.114E-01 (bud neck) 4.457E-04 (ASH1)

ALPHA1(1) AND SWI5(1) AND MCB(1) => SimExpr(YML027W) OR SimExpr(other) : 7 3

EXPR: (0.118) SWI5 (P < 0.000) MCB (P < 0.012) ALPHA1 (P < 0.000)

ORF SYMBOL P F C TF
YKR077W NO SYMBOL
|YLR049C| NO SYMBOL MBP1, SWI5
YDR134C NO SYMBOL ASH1, NRG1, SOK2, SWI4
|YJR030C| NO SYMBOL MBP1, PHO4, RTG1, SWI6
|YER132C| PMD1 sporulation ->
sporulation SMP1
YPR185W APG13 protein-vacuolar targeting, autophagy ->
organelle organization and biogenesis, autophagy, intracellular protein transport, protein metabolism protein binding ->
protein binding extrinsic to membrane ->
extrinsic to membrane MET4, SWI6
YFR027W ECO1 sister chromatid cohesion, DNA replication, DNA repair ->
DNA replication and chromosome cycle, DNA repair, mitotic cell cycle, DNA metabolism acetyltransferase activity ->
acetyltransferase activity nuclear chromatin ->
chromosome, nucleus
YMR076C PDS5 mitotic sister chromatid cohesion, mitotic chromosome condensation ->
DNA replication and chromosome cycle, M phase, mitotic cell cycle structural molecule activity ->
structural molecule activity condensed nuclear chromosome ->
chromosome, nucleus FKH2, MBP1, SWI6
YML027W YOX1 negative regulation of transcription from Pol II promoter\, mitotic, regulation of mitotic cell cycle ->
mitotic cell cycle, M phase, regulation of transcription, nuclear division, transcription\, DNA-dependent, regulation of cell cycle specific transcriptional repressor activity, DNA binding ->
specific transcriptional repressor activity, DNA binding nucleus ->
nucleus MBP1, SWI4, SWI6
YMR179W SPT21 regulation of transcription from Pol II promoter ->
regulation of transcription, transcription\, DNA-dependent MBP1, STB1, SWI4, SWI6, UGA3
Main: mitotic cell cycle (0.50) DNA binding (0.25) nucleus (0.75) MBP1 SWI6 (0.62)
Score: 0.27 0.00 0.50 0.571
P-value: 1.053E-02 (sister chromatid cohesion) 2.575E+00 (binding) 2.915E-01 (nuclear chromosome) 4.452E-05 (SWI6)

MCM1(1) AND ALPHA1(1) AND MCB(1) => SimExpr(YML027W) OR SimExpr(other) : 5 1

EXPR: (0.102) MCB (P < 0.008) MCM1 (P < 0.000) ALPHA1 (P < 0.000)

ORF SYMBOL P F C TF
YKR077W NO SYMBOL
YCL024W KCC4 septin checkpoint, protein amino acid phosphorylation, bud growth, axial budding, septin ring assembly ->
cell cycle, phosphate metabolism, budding, septin ring assembly, protein modification protein kinase activity ->
protein kinase activity bud neck ->
bud neck ASH1, CIN5, DAL81, HSF1, MET4, PHD1, RAP1, STP1, STP2
YNR028W CPR8 peptidyl-prolyl cis-trans isomerase activity ->
peptidyl-prolyl cis-trans isomerase activity ASH1, DIG1, MCM1
YCR065W HCM1 spindle assembly, transcription initiation from Pol II promoter ->
cytoplasm organization and biogenesis, cell cycle, transcription specific RNA polymerase II transcription factor activity ->
specific RNA polymerase II transcription factor activity nucleus ->
nucleus ASH1, HSF1, MBP1, NDD1, PHD1, ROX1, STB1, SWI4
|YGR189C| CRH1 cell wall, incipient bud site ->
cell wall, incipient bud site GRF10(Pho2), MBP1, RLM1, STE12, SWI4, SWI5
YML027W YOX1 negative regulation of transcription from Pol II promoter\, mitotic, regulation of mitotic cell cycle ->
regulation of transcription, M phase, transcription, cell cycle specific transcriptional repressor activity, DNA binding ->
specific transcriptional repressor activity, DNA binding nucleus ->
nucleus MBP1, SWI4, SWI6
Main: cell cycle (1.00) DNA binding (0.25) nucleus (0.50) SWI4 ASH1 MBP1 (0.60)
Score: 1.00 0.00 0.17 0.600
P-value: 1.856E-01 (regulation of cell cycle) 3.367E-01 (transcription regulator activity) 3.369E+00 (nucleus) 2.445E-04 (ASH1)

MCM1(1) AND ECB(1) AND MCB(1) => SimExpr(YML027W) OR SimExpr(other) : 5 1

EXPR: (0.111) ECB (P < 0.000) MCB (P < 0.028) MCM1 (P < 0.000)

ORF SYMBOL P F C TF
YCL024W KCC4 septin checkpoint, protein amino acid phosphorylation, bud growth, axial budding, septin ring assembly ->
cell cycle, phosphate metabolism, budding, septin ring assembly, protein modification protein kinase activity ->
protein kinase activity bud neck ->
bud neck ASH1, CIN5, DAL81, HSF1, MET4, PHD1, RAP1, STP1, STP2
YNR028W CPR8 peptidyl-prolyl cis-trans isomerase activity ->
peptidyl-prolyl cis-trans isomerase activity ASH1, DIG1, MCM1
YCR065W HCM1 spindle assembly, transcription initiation from Pol II promoter ->
cytoplasm organization and biogenesis, cell cycle, transcription specific RNA polymerase II transcription factor activity ->
specific RNA polymerase II transcription factor activity nucleus ->
nucleus ASH1, HSF1, MBP1, NDD1, PHD1, ROX1, STB1, SWI4
YDR507C GIN4 septin checkpoint, protein amino acid phosphorylation, bud growth, axial budding, septin ring assembly ->
cell cycle, phosphate metabolism, budding, septin ring assembly, protein modification protein kinase activity ->
protein kinase activity bud neck ->
bud neck GRF10(Pho2), GTS1, MBP1, MCM1, SWI4, SWI6
|YGR189C| CRH1 cell wall, incipient bud site ->
cell wall, incipient bud site GRF10(Pho2), MBP1, RLM1, STE12, SWI4, SWI5
YML027W YOX1 negative regulation of transcription from Pol II promoter\, mitotic, regulation of mitotic cell cycle ->
regulation of transcription, M phase, transcription, cell cycle specific transcriptional repressor activity, DNA binding ->
specific transcriptional repressor activity, DNA binding nucleus ->
nucleus MBP1, SWI4, SWI6
Main: cell cycle (1.00) protein kinase activity (0.40) nucleus (0.40) SWI4 MBP1 (0.67)
Score: 1.00 0.10 0.20 0.667
P-value: 2.209E-04 (septin checkpoint) 2.664E-01 (protein kinase activity) 8.080E-02 (bud neck) 2.055E-04 (MBP1)

MCM1(1) AND SFF'(1) AND STE12(1) AND MCM1'(1) => SimExpr(YDR309C) OR SimExpr(other) : 6 2

EXPR: (0.114) SFF' (P < 0.000) STE12 (P < 0.001) MCM1' (P < 0.000) MCM1 (P < 0.000)

ORF SYMBOL P F C TF
YDR309C GIC2 axial budding, Rho protein signal transduction, establishment of cell polarity (sensu Saccharomyces) ->
asexual reproduction, signal transduction, cell organization and biogenesis small GTPase regulatory/interacting protein activity ->
small GTPase regulatory/interacting protein activity actin cap (sensu Saccharomyces), bud tip, shmoo tip, incipient bud site ->
cell cortex, site of polarized growth (sensu Fungi), incipient bud site, cytoplasm ASH1, HSF1, MBP1, PHD1, RLM1, SKN7, STB1, STE12, SWI4, SWI6
|YHR023W| MYO1 cytokinesis, response to osmotic stress, axial budding ->
cell proliferation, response to abiotic stimulus, asexual reproduction microfilament motor activity ->
microfilament motor activity contractile ring (sensu Saccharomyces) ->
site of polarized growth (sensu Fungi), cell cortex, cytoplasm
YKR013W PRY2 SWI4, SWI6
YNL053W MSG5 adaptation to pheromone during conjugation with cellular fusion ->
conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus prenylated protein tyrosine phosphatase activity ->
prenylated protein tyrosine phosphatase activity DIG1, FKH1, MCM1
YJL157C FAR1 signal transduction during conjugation with cellular fusion, cell cycle arrest ->
signal transduction, cell proliferation, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus cyclin-dependent protein kinase inhibitor activity ->
cyclin-dependent protein kinase inhibitor activity cytoplasm, nucleus ->
cytoplasm, nucleus MCM1
YGR146C NO SYMBOL HSF1
|YAR018C| KIN3 chromosome segregation ->
cell proliferation protein kinase activity ->
protein kinase activity FKH2, MCM1, MSS11, NDD1
YHR005C GPA1 signal transduction during conjugation with cellular fusion ->
signal transduction, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus heterotrimeric G-protein GTPase activity ->
heterotrimeric G-protein GTPase activity heterotrimeric G-protein complex, plasma membrane ->
extrinsic to membrane, plasma membrane DIG1, IXR1, MCM1, PHD1, SOK2, STE12
Main: response to abiotic stimulus (0.67) heterotrimeric G-protein GTPase activity (0.17) cytoplasm (0.75) MCM1 (0.57)
Score: 0.73 0.00 0.50 0.429
P-value: 2.435E-04 (reproduction) 1.759E+00 (hydrolase activity) 2.090E-01 (cell cortex) 1.848E-03 (MCM1)

RAP1(1) AND SFF(1) AND SWI5(1) AND SCB(1) => SimExpr(YLR344W) : 5

EXPR: (0.072) SFF (P < 0.000) SWI5 (P < 0.000) SCB (P < 0.000) RAP1 (P < 0.003)

RAP1(1) AND SFF'(1) AND SWI5(1) AND SCB(1) => SimExpr(YLR344W) : 5

EXPR: (0.072) SFF' (P < 0.000) SWI5 (P < 0.000) SCB (P < 0.000) RAP1 (P < 0.001)

ALPHA1(1) AND SFF(1) AND PDR(1) AND ATRepeat(1) => SimExpr(YLR121C) OR SimExpr(other) : 5 2

EXPR: (0.125) SFF (P < 0.000) PDR (P < 0.003) ATRepeat (P < 0.001) ALPHA1 (P < 0.000)

ORF SYMBOL P F C TF
YGL197W MDS3 sporulation ->
sporulation cytoplasm ->
cytoplasm MTH1
YOR153W PDR5 drug transport, response to drug ->
transport, response to abiotic stimulus xenobiotic-transporting ATPase activity ->
xenobiotic-transporting ATPase activity plasma membrane ->
plasma membrane YAP6
YER062C HOR2 carbohydrate metabolism, response to osmotic stress, glycerol biosynthesis ->
carbohydrate metabolism, response to abiotic stimulus, alcohol metabolism, energy derivation by oxidation of organic compounds, glycerol ether metabolism, lipid metabolism, biosynthesis glycerol-1-phosphatase activity ->
glycerol-1-phosphatase activity MTH1
|YDR226W| ADK1 cell proliferation ->
cell proliferation adenylate kinase activity ->
adenylate kinase activity cytoplasm, mitochondrial intermembrane space ->
cytoplasm PUT3
|YDL048C| STP4 HIR2
YOR273C TPO4 polyamine transport ->
transport spermine transporter activity, spermidine transporter activity ->
spermine transporter activity, spermidine transporter activity plasma membrane, vacuolar membrane ->
plasma membrane, cytoplasm ARO80, BAS1, FZF1, HIR1, IME4, NRG1, PDR1, PHO4, SFP1, SKN7, STP1
YLR121C YPS3 protein metabolism ->
protein metabolism aspartic-type endopeptidase activity ->
aspartic-type endopeptidase activity plasma membrane ->
plasma membrane CIN5, SWI4, YAP6
Main: response to abiotic stimulus (0.33) adenylate kinase activity (0.20) cytoplasm (0.60) MTH1 YAP6 (0.29)
Score: 0.13 0.00 0.60 0.095
P-value: 3.758E-01 (response to abiotic stimulus) 5.825E-01 (hydrolase activity) 8.418E-02 (plasma membrane) 1.381E-01 (MTH1)

mRRPE(1) AND PAC(1) AND MCM1'(1) => SimExpr(YGL029W) OR SimExpr(other) : 13 5

EXPR: (0.133) mRRPE (P < 0.000) PAC (P < 0.007) MCM1' (P < 0.000)

ALPHA1'(1) AND mRRPE(1) AND PAC(1) AND MCM1'(1) => SimExpr(YGL029W) OR SimExpr(other) : 9 2

EXPR: (0.122) ALPHA1' (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.004) MCM1' (P < 0.000)

SFF'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YGL029W) OR SimExpr(other) : 33 14

EXPR: (0.138) SFF' (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.000)

SFF(1) AND mRRPE(1) AND PAC(1) => SimExpr(YGL029W) OR SimExpr(other) : 26 11

EXPR: (0.133) SFF (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.000)

ALPHA1'(1) AND SFF'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YGL029W) OR SimExpr(other) : 21 8

EXPR: (0.136) ALPHA1' (P < 0.000) SFF' (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.001)

SFF'(1) AND mRRPE(1) AND PAC(1) AND MCM1'(1) => SimExpr(YGL029W) OR SimExpr(other) : 6 2

EXPR: (0.132) SFF' (P < 0.000) mRRPE (P < 0.008) PAC (P < 0.034) MCM1' (P < 0.000)

ORF SYMBOL P F C TF
YML125C NO SYMBOL MAL13, MSN4, NDD1, RME1, SWI5
YOR310C NOP58 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
rRNA modification, rRNA processing small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex ABF1, SWI6
|YDR279W| RNH202 GCR2, MBP1, RIM101, RLM1, SWI6, THI2
YCR016W NO SYMBOL
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
rRNA processing, snRNA processing RNA binding ->
RNA binding nucleolus ->
nucleus
YGL029W CGR1 ribosome biogenesis, rRNA processing ->
ribosome biogenesis, rRNA processing nucleolus ->
nucleus
YOR095C RKI1 pentose-phosphate shunt ->
glucose catabolism, main pathways of carbohydrate metabolism, nicotinamide metabolism ribose-5-phosphate isomerase activity ->
ribose-5-phosphate isomerase activity FHL1, FKH2, RAP1
|YIL122W| POG1 re-entry into mitotic cell cycle after pheromone arrest ->
re-entry into mitotic cell cycle, conjugation with cellular fusion, response to pheromone specific RNA polymerase II transcription factor activity ->
specific RNA polymerase II transcription factor activity nucleus ->
nucleus ASH1, CIN5, NRG1, RLM1, SMP1, YAP6
Main: rRNA processing (0.60) RNA binding (0.33) nucleus (1.00) RLM1 SWI6 (0.40)
Score: 0.30 0.00 1.00 0.200
P-value: 2.861E-02 (rRNA processing) 2.000E+00 1.986E-02 (nucleolus) 2.636E-01 (RLM1)

SFF(1) AND mRRPE(1) AND PAC(1) AND MCM1'(1) => SimExpr(YGL029W) OR SimExpr(other) : 5 1

EXPR: (0.112) SFF (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.003) MCM1' (P < 0.000)

ORF SYMBOL P F C TF
YML125C NO SYMBOL MAL13, MSN4, NDD1, RME1, SWI5
|YDR279W| RNH202 GCR2, MBP1, RIM101, RLM1, SWI6, THI2
YCR016W NO SYMBOL
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
rRNA processing, snRNA processing RNA binding ->
RNA binding nucleolus ->
nucleolus
YML093W UTP14 processing of 20S pre-rRNA ->
rRNA processing snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleolus, ribonucleoprotein complex
YGL029W CGR1 ribosome biogenesis, rRNA processing ->
ribosome biogenesis, rRNA processing nucleolus ->
nucleolus
Main: rRNA processing (1.00) RNA binding (1.00) nucleolus (1.00) GCR2 (0.50)
Score: 1.00 1.00 1.00 0.000
P-value: 1.011E-02 (rRNA processing) 3.853E-01 (RNA binding) 7.533E-03 (nucleolus) 3.288E-01 (THI2)

ALPHA1'(1) AND SFF'(1) AND mRRPE(1) AND PAC(1) AND MCM1'(1) => SimExpr(YGL029W) OR SimExpr(other) : 5 1

EXPR: (0.116) ALPHA1' (P < 0.000) SFF' (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.009) MCM1' (P < 0.000)

ALPHA1(1) AND ALPHA1'(1) AND SFF'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YGL029W) OR SimExpr(other) : 6 3

EXPR: (0.134) ALPHA1' (P < 0.000) SFF' (P < 0.000) mRRPE (P < 0.007) PAC (P < 0.029) ALPHA1 (P < 0.000)

ORF SYMBOL P F C TF
|YPR183W| DPM1 N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
protein amino acid glycosylation, phosphoinositide biosynthesis, protein lipidation, phosphoinositide metabolism transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network SWI5
YOL022C NO SYMBOL MAC1, MOT3, RTS2
YJL109C UTP10 processing of 20S pre-rRNA ->
rRNA processing snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleolus, ribonucleoprotein complex
YNL075W IMP4 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
rRNA modification, rRNA processing rRNA primary transcript binding ->
RNA binding small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex ->
nucleolus, small nuclear ribonucleoprotein complex, ribonucleoprotein complex USV1
|YCR072C| NO SYMBOL YFL044C
YGL029W CGR1 ribosome biogenesis, rRNA processing ->
ribosome biogenesis, rRNA processing nucleolus ->
nucleolus
YOR095C RKI1 pentose-phosphate shunt ->
glucose catabolism, main pathways of carbohydrate metabolism, nicotinamide metabolism ribose-5-phosphate isomerase activity ->
intramolecular isomerase activity FHL1, FKH2, RAP1
|YHR169W| DBP8 35S primary transcript processing ->
rRNA processing ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleolus
YJL033W HCA4 35S primary transcript processing ->
rRNA processing ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleolus HIR2, USV1
Main: rRNA processing (0.71) RNA binding (0.67) nucleolus (0.83) USV1 (0.33)
Score: 0.48 0.40 0.67 0.067
P-value: 6.428E-05 (rRNA processing) 2.135E-02 (ATP dependent RNA helicase activity) 9.523E-05 (nucleolus) 5.402E-02 (USV1)

RAP1(1) AND ALPHA1(1) AND SCB(1) => SimExpr(YGR085C) OR SimExpr(other) : 5 1

EXPR: (0.100) SCB (P < 0.000) RAP1 (P < 0.027) ALPHA1 (P < 0.000)

RAP1(1) AND ALPHA1(1) AND SFF(1) AND SCB(1) => SimExpr(YGR085C) : 5

EXPR: (0.086) SFF (P < 0.000) SCB (P < 0.000) RAP1 (P < 0.008) ALPHA1 (P < 0.000)

ORF SYMBOL P F C TF
YPL131W RPL5 protein biosynthesis, ribosomal large subunit assembly and maintenance ->
protein biosynthesis, ribosome biogenesis and assembly RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome FHL1, GAT3, RAP1
YGR085C RPL11B protein biosynthesis, ribosomal large subunit assembly and maintenance ->
protein biosynthesis, ribosome biogenesis and assembly structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome FHL1, MIG1
YLR249W YEF3 translational elongation ->
protein biosynthesis translation elongation factor activity ->
translation elongation factor activity ribosome ->
ribosome INO2, INO4
YBL087C RPL23A protein biosynthesis ->
protein biosynthesis structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome FHL1, IXR1, MSS11, PDR1, RAP1, SMP1, SOK2
YHL033C RPL8A protein biosynthesis ->
protein biosynthesis structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome FHL1
Main: protein biosynthesis (1.00) structural constituent of ribosome (0.80) ribosome (1.00) FHL1 (0.80)
Score: 1.00 0.60 1.00 0.600
P-value: 3.152E-04 (protein biosynthesis) 4.489E-04 (structural constituent of ribosome) 2.344E-05 (cytosolic large ribosomal subunit (sensu Eukarya)) 6.441E-05 (FHL1)

RAP1(1) AND ALPHA1(1) AND SFF'(1) AND SCB(1) => SimExpr(YGR085C) : 5

EXPR: (0.086) SFF' (P < 0.000) SCB (P < 0.000) RAP1 (P < 0.010) ALPHA1 (P < 0.000)

ORF SYMBOL P F C TF
YPL131W RPL5 protein biosynthesis, ribosomal large subunit assembly and maintenance ->
protein biosynthesis, ribosome biogenesis and assembly RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome FHL1, GAT3, RAP1
YGR085C RPL11B protein biosynthesis, ribosomal large subunit assembly and maintenance ->
protein biosynthesis, ribosome biogenesis and assembly structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome FHL1, MIG1
YLR249W YEF3 translational elongation ->
protein biosynthesis translation elongation factor activity ->
translation elongation factor activity ribosome ->
ribosome INO2, INO4
YBL087C RPL23A protein biosynthesis ->
protein biosynthesis structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome FHL1, IXR1, MSS11, PDR1, RAP1, SMP1, SOK2
YHL033C RPL8A protein biosynthesis ->
protein biosynthesis structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome FHL1
Main: protein biosynthesis (1.00) structural constituent of ribosome (0.80) ribosome (1.00) FHL1 (0.80)
Score: 1.00 0.60 1.00 0.600
P-value: 3.152E-04 (protein biosynthesis) 4.489E-04 (structural constituent of ribosome) 2.344E-05 (cytosolic large ribosomal subunit (sensu Eukarya)) 6.441E-05 (FHL1)

mRRPE(1) AND PAC(1) => SimExpr(YNL110C) OR SimExpr(other) : 68 22

EXPR: (0.132) mRRPE (P < 0.000) PAC (P < 0.000)

LYS14(1) AND mRRPE(1) AND PAC(1) => SimExpr(YNL110C) OR SimExpr(other) : 7 2

ALPHA1(1) AND SWI5(1) AND MCB(1) => SimExpr(YPR185W) OR SimExpr(other) : 7 3

RAP1(1) AND SWI5(1) AND SCB(1) => SimExpr(YMR194W) OR SimExpr(other) : 5 1

EXPR: (0.091) SWI5 (P < 0.000) SCB (P < 0.000) RAP1 (P < 0.020)

RAP1(1) AND SFF'(1) AND SCB(1) => SimExpr(YMR194W) OR SimExpr(other) : 8 3

EXPR: (0.103) SFF' (P < 0.000) SCB (P < 0.000) RAP1 (P < 0.008)

RAP1(1) AND SFF(1) AND SCB(1) => SimExpr(YMR194W) OR SimExpr(other) : 8 2

EXPR: (0.098) SFF (P < 0.000) SCB (P < 0.000) RAP1 (P < 0.007)

RAP1(1) AND SFF(1) AND SWI5(1) AND SCB(1) => SimExpr(YMR194W) : 5

RAP1(1) AND SFF'(1) AND SWI5(1) AND SCB(1) => SimExpr(YMR194W) : 5

RAP1(1) AND SCB(1) => SimExpr(YHL033C) OR SimExpr(other) : 9 4

EXPR: (0.113) SCB (P < 0.000) RAP1 (P < 0.027)

RAP1(1) AND ALPHA1(1) AND SCB(1) => SimExpr(YHL033C) OR SimExpr(other) : 5 1

RAP1(1) AND ALPHA1(1) AND SFF'(1) AND SCB(1) => SimExpr(YHL033C) : 5

RAP1(1) AND ALPHA1(1) AND SFF(1) AND SCB(1) => SimExpr(YHL033C) : 5

RAP1(1) AND ALPHA1(1) AND mRRPE(1) => SimExpr(YMR116C) OR SimExpr(other) : 5 2

EXPR: (0.128) mRRPE (P < 0.000) RAP1 (P < 0.174) ALPHA1 (P < 0.000)

ORF SYMBOL P F C TF
|YKL072W| STB6 ARG81, ARO80, BAS1, CIN5, GCN4, GLN3, HAP3, MCM1, PHD1, REB1, RLM1, YJL206C, ZAP1
YDL130W RPP1B protein biosynthesis, translational elongation ->
protein biosynthesis structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, GAL4, RAP1, RFX1
YMR116C ASC1 cytoplasm ->
cytoplasm FHL1, RAP1
YMR013C SEC59 protein-ER targeting, protein amino acid glycosylation ->
organelle organization and biogenesis, protein biosynthesis, intracellular protein transport, secretory pathway, protein modification, glycoprotein metabolism, protein metabolism dolichol kinase activity ->
dolichol kinase activity membrane ->
membrane FHL1, NDD1, RAP1, RLM1, RME1
|YPR080W| TEF1 translational elongation ->
protein biosynthesis translation elongation factor activity ->
translation elongation factor activity ribosome ->
cytoplasm, ribonucleoprotein complex FHL1, PDR1, RAP1, YAP5
YLR249W YEF3 translational elongation ->
protein biosynthesis translation elongation factor activity ->
translation elongation factor activity ribosome ->
cytoplasm, ribonucleoprotein complex INO2, INO4
YBR048W RPS11B protein biosynthesis, ribosomal small subunit assembly and maintenance, regulation of translational fidelity ->
ribosome biogenesis and assembly, protein biosynthesis structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex GAL4, HAP4, LEU3, MET31, MSN1
Main: protein biosynthesis (1.00) translation elongation factor activity (0.40) cytoplasm (0.83) RAP1 FHL1 (0.57)
Score: 1.00 0.20 0.67 0.381
P-value: 9.360E-05 (translational elongation) 4.519E-03 (translation elongation factor activity) 1.212E-02 (ribosome) 1.050E-03 (FHL1)

RAP1(1) AND SCB(1) => SimExpr(YOR369C) OR SimExpr(other) : 9 4

RAP1(1) AND SWI5(1) AND SCB(1) => SimExpr(YOR369C) OR SimExpr(other) : 5 1

RAP1(1) AND SFF'(1) AND SCB(1) => SimExpr(YOR369C) OR SimExpr(other) : 9 2

RAP1(1) AND SFF(1) AND SCB(1) => SimExpr(YOR369C) OR SimExpr(other) : 8 2

RAP1(1) AND SFF(1) AND SWI5(1) AND SCB(1) => SimExpr(YOR369C) : 5

RAP1(1) AND SFF'(1) AND SWI5(1) AND SCB(1) => SimExpr(YOR369C) : 5

RAP1(1) AND SCB(1) => SimExpr(YPL131W) OR SimExpr(other) : 9 4

RAP1(1) AND ALPHA1(1) AND SCB(1) => SimExpr(YPL131W) OR SimExpr(other) : 5 1

RAP1(1) AND ALPHA1(1) AND SFF'(1) AND SCB(1) => SimExpr(YPL131W) : 5

RAP1(1) AND ALPHA1(1) AND SFF(1) AND SCB(1) => SimExpr(YPL131W) : 5

RAP1(1) AND SFF(1) AND SWI5(1) => SimExpr(YLR441C) OR SimExpr(other) : 13 6

EXPR: (0.129) SFF (P < 0.000) SWI5 (P < 0.000) RAP1 (P < 0.184)

RAP1(1) AND SCB(1) => SimExpr(YLR249W) OR SimExpr(other) : 9 4

RAP1(1) AND SFF(1) AND SWI5(1) AND SCB(1) => SimExpr(YLR249W) : 5

RAP1(1) AND ALPHA1(1) AND SFF(1) AND SCB(1) => SimExpr(YLR249W) : 5

RAP1(1) AND SFF'(1) AND SWI5(1) AND SCB(1) => SimExpr(YLR249W) : 5

RAP1(1) AND SFF(1) AND SWI5(1) AND SCB(1) => SimExpr(YBL087C) : 5

RAP1(1) AND ALPHA1(1) AND SFF'(1) AND SCB(1) => SimExpr(YBL087C) : 5

RAP1(1) AND ALPHA1(1) AND SFF(1) AND SCB(1) => SimExpr(YBL087C) : 5

RAP1(1) AND SFF'(1) AND SWI5(1) AND SCB(1) => SimExpr(YBL087C) : 5

LYS14(1) AND mRRPE(1) AND PAC(1) => SimExpr(YMR290C) OR SimExpr(other) : 8 1

LYS14(1) AND SFF(1) AND mRRPE(1) AND PAC(1) => SimExpr(YMR290C) : 5

EXPR: (0.106) LYS14 (P < 0.000) SFF (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.000)

ORF SYMBOL P F C TF
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
rRNA processing, snRNA processing RNA binding ->
RNA binding nucleolus ->
nucleolus
YML093W UTP14 processing of 20S pre-rRNA ->
rRNA processing snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleolus, ribonucleoprotein complex
YMR259C NO SYMBOL ARG80, GCR2, GTS1, HIR1, SRD1
YHR052W CIC1 protein catabolism ->
protein catabolism protein binding\, bridging ->
protein binding\, bridging nucleolus, proteasome complex (sensu Eukarya) ->
nucleolus, cytosol, endoplasmic reticulum, nucleus HAP4, MATa1
YMR290C HAS1 nucleolus, nuclear membrane ->
nucleolus, nuclear membrane RAP1
Main: rRNA processing (0.67) RNA binding (0.67) nucleolus (1.00) GCR2 (0.33)
Score: 0.33 0.33 1.00 0.000
P-value: 1.630E-01 (rRNA processing) 2.709E-01 (RNA binding) 7.963E-05 (nucleolus) 3.566E-01 (MATa1)

mRRPE(1) AND PAC(1) => SimExpr(YMR229C) OR SimExpr(other) : 64 26

ALPHA1'(1) AND mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YJL109C) OR SimExpr(other) : 7 3

EXPR: (0.130) ALPHA1' (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.005) SCB (P < 0.000)

ALPHA1'(1) AND SFF'(1) AND mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YJL109C) OR SimExpr(other) : 5 2

EXPR: (0.122) ALPHA1' (P < 0.000) SFF' (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.001) SCB (P < 0.000)

ORF SYMBOL P F C TF
YOR310C NOP58 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
rRNA modification, rRNA processing small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex ->
small nuclear ribonucleoprotein complex, nucleolus, ribonucleoprotein complex ABF1, SWI6
|YOR078W| BUD21 processing of 20S pre-rRNA ->
rRNA processing snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleolus, ribonucleoprotein complex ABF1, MSS11, SIG1, SKO1
YJL109C UTP10 processing of 20S pre-rRNA ->
rRNA processing snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleolus, ribonucleoprotein complex
YCL059C KRR1 ribosome biogenesis, rRNA processing ->
ribosome biogenesis, rRNA processing nucleolus ->
nucleolus
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
rRNA processing, snRNA processing RNA binding ->
RNA binding nucleolus ->
nucleolus
|YNL112W| DBP2 RNA helicase activity ->
RNA binding bud neck ->
site of polarized growth (sensu Saccharomyces)
YBR104W YMC2 transport ->
transport transporter activity ->
transporter activity mitochondrial inner membrane ->
mitochondrion, inner membrane FKH1, FKH2
Main: rRNA processing (0.83) RNA binding (0.80) nucleolus (0.71) ABF1 (0.67)
Score: 0.67 0.60 0.48 0.333
P-value: 1.127E-05 (rRNA processing) 6.477E-03 (snoRNA binding) 1.695E-05 (nucleolus) 5.107E-01 (SKO1)

ALPHA1(1) AND ALPHA2(1) AND MCB(1) => SimExpr(YOR144C) OR SimExpr(other) : 6 3

EXPR: (0.132) ALPHA2 (P < 0.000) MCB (P < 0.048) ALPHA1 (P < 0.001)

ORF SYMBOL P F C TF
YNL082W PMS1 mismatch repair, meiosis ->
DNA metabolism, cell proliferation ATPase activity, ATP binding, DNA binding ->
ATP binding, DNA binding, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides nuclear chromosome ->
intracellular MTH1
|YOR284W| HUA2 RFX1, YAP6
YJL095W BCK1 protein amino acid phosphorylation, protein kinase cascade, response to nutrients, establishment of cell polarity (sensu Saccharomyces) ->
phosphorus metabolism, signal transduction, response to extracellular stimulus, cell organization and biogenesis, protein metabolism, response to abiotic stimulus MAP kinase kinase kinase activity ->
protein kinase activity intracellular ->
intracellular YAP1
YPR185W APG13 protein-vacuolar targeting, autophagy ->
cell organization and biogenesis, autophagy, protein metabolism, transport protein binding ->
protein binding extrinsic to membrane ->
extrinsic to membrane MET4, SWI6
YOR144C ELG1 negative regulation of DNA transposition, negative regulation of DNA recombination ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism YJL206C
YCR065W HCM1 spindle assembly, transcription initiation from Pol II promoter ->
cell organization and biogenesis, cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism specific RNA polymerase II transcription factor activity ->
specific RNA polymerase II transcription factor activity nucleus ->
intracellular ASH1, HSF1, MBP1, NDD1, PHD1, ROX1, STB1, SWI4
YFR027W ECO1 sister chromatid cohesion, DNA replication, DNA repair ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, cell proliferation acetyltransferase activity ->
acyltransferase activity nuclear chromatin ->
intracellular
|YER047C| SAP1 MSS11
|YPL140C| MKK2 protein amino acid phosphorylation, signal transduction ->
phosphorus metabolism, signal transduction, protein metabolism MAP kinase kinase activity ->
protein kinase activity intracellular ->
intracellular FKH1, FKH2
Main: cell organization and biogenesis (0.43) protein kinase activity (0.33) intracellular (0.83) SWI4 (0.12)
Score: 0.48 0.07 0.67 0.000
P-value: 6.497E-01 (DNA replication) 5.827E-01 (protein kinase activity) 2.383E-01 (nuclear chromosome) 1.000E+00

ALPHA1(1) AND ALPHA1'(1) AND SFF(1) AND mRRPE(1) AND PAC(1) => SimExpr(YJL033W) OR SimExpr(other) : 5 2

EXPR: (0.130) ALPHA1' (P < 0.000) SFF (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.011) ALPHA1 (P < 0.000)

ORF SYMBOL P F C TF
|YPR183W| DPM1 N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
protein amino acid glycosylation, phosphoinositide biosynthesis, protein lipidation, phosphoinositide metabolism transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network SWI5
YOL022C NO SYMBOL MAC1, MOT3, RTS2
YJL109C UTP10 processing of 20S pre-rRNA ->
rRNA processing snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleolus, ribonucleoprotein complex
|YCR072C| NO SYMBOL YFL044C
YGL029W CGR1 ribosome biogenesis, rRNA processing ->
ribosome biogenesis, rRNA processing nucleolus ->
nucleolus
YHR169W DBP8 35S primary transcript processing ->
rRNA processing ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleolus
YJL033W HCA4 35S primary transcript processing ->
rRNA processing ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleolus HIR2, USV1
Main: rRNA processing (0.80) RNA binding (0.75) nucleolus (0.80) RTS2 (0.25)
Score: 0.60 0.50 0.60 0.000
P-value: 5.741E-04 (rRNA processing) 1.253E-02 (ATP dependent RNA helicase activity) 5.230E-04 (nucleolus) 4.642E-01 (RTS2)

ALPHA2(1) AND SFF'(1) AND MCB(1) => SimExpr(YFR027W) OR SimExpr(other) : 5 1

EXPR: (0.129) ALPHA2 (P < 0.000) SFF' (P < 0.000) MCB (P < 0.019)

ORF SYMBOL P F C TF
YJL095W BCK1 protein amino acid phosphorylation, protein kinase cascade, response to nutrients, establishment of cell polarity (sensu Saccharomyces) ->
phosphorus metabolism, signal transduction, response to extracellular stimulus, cell organization and biogenesis, protein metabolism, response to abiotic stimulus MAP kinase kinase kinase activity ->
protein kinase activity intracellular ->
intracellular YAP1
YPR185W APG13 protein-vacuolar targeting, autophagy ->
cell organization and biogenesis, autophagy, protein metabolism, transport protein binding ->
protein binding extrinsic to membrane ->
extrinsic to membrane MET4, SWI6
YFR027W ECO1 sister chromatid cohesion, DNA replication, DNA repair ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, cell proliferation acetyltransferase activity ->
acyltransferase activity intracellular ->
intracellular
YPL140C MKK2 protein amino acid phosphorylation, signal transduction ->
phosphorus metabolism, signal transduction, protein metabolism MAP kinase kinase activity ->
protein kinase activity intracellular ->
intracellular FKH1, FKH2
YDR297W SUR2 sphingolipid metabolism, sphingolipid biosynthesis ->
lipid metabolism, biosynthesis sphingosine hydroxylase activity ->
sphingosine hydroxylase activity intracellular ->
intracellular CBF1, MTH1
|YPL241C| CIN2 microtubule-based process ->
cell organization and biogenesis HIR2
Main: cell organization and biogenesis (0.50) protein kinase activity (0.40) intracellular (0.80) MTH1 (0.20)
Score: 0.33 0.10 0.60 0.000
P-value: 1.834E-01 (protein amino acid phosphorylation) 2.368E-01 (protein kinase activity) 3.838E+00 (intracellular) 6.695E-01 (MET4)

ALPHA1'(1) AND STE12(1) AND PAC(1) => SimExpr(YPR137W) OR SimExpr(other) : 5 1

EXPR: (0.129) ALPHA1' (P < 0.000) STE12 (P < 0.000) PAC (P < 0.020)

ORF SYMBOL P F C TF
YGR158C MTR3 35S primary transcript processing, mRNA catabolism ->
cell organization and biogenesis, catabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism 3'-5' exoribonuclease activity ->
hydrolase activity\, acting on ester bonds, RNA binding nuclear exosome (RNase complex), cytoplasmic exosome (RNase complex) ->
exosome (RNase complex), cytoplasm, nucleus ZMS1
YPR137W RRP9 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex ABF1, HIR1, RCS1
YNL308C KRI1 ribosome biogenesis ->
cell organization and biogenesis nucleolus ->
nucleus
|YMR302C| PRP12 mitochondrial genome maintenance, rRNA processing ->
cell organization and biogenesis, RNA metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism exonuclease activity ->
hydrolase activity\, acting on ester bonds mitochondrial inner membrane ->
cytoplasm, inner membrane
YGR251W NO SYMBOL MSN4, PHD1, SKN7
YAL059W ECM1 cell wall organization and biogenesis ->
cell organization and biogenesis MOT3
Main: cell organization and biogenesis (1.00) RNA binding (0.67) nucleus (0.75) ABF1 (0.25)
Score: 1.00 0.67 0.67 0.000
P-value: 7.075E-04 (ribosome biogenesis) 1.507E-02 (exonuclease activity) 1.602E-01 (nucleolus) 3.331E-01 (ZMS1)

ALPHA2(1) AND ALPHA1'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YJR070C) OR SimExpr(other) : 5 2

EXPR: (0.126) ALPHA2 (P < 0.000) ALPHA1' (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.002)

ORF SYMBOL P F C TF
YJR070C NO SYMBOL GAT3, YAP5
YPR183W DPM1 N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
lipid biosynthesis, biosynthesis, membrane lipid metabolism, protein metabolism, lipoprotein metabolism transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network SWI5
YMR049C ERB1 rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RTG3
|YGL029W| CGR1 ribosome biogenesis, rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism nucleolus ->
nucleolus
YHR128W FUR1 pyrimidine salvage ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism uracil phosphoribosyltransferase activity ->
transferase activity\, transferring glycosyl groups CIN5
|YJL033W| HCA4 35S primary transcript processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleolus HIR2, USV1
YLR222C UTP13 processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleolus, ribonucleoprotein complex ABF1
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.83) RNA binding (0.50) nucleolus (0.75) ABF1 (0.17)
Score: 0.73 0.33 0.50 0.000
P-value: 5.741E-04 (rRNA processing) 1.075E-01 (transferase activity\, transferring glycosyl groups) 1.279E-02 (nucleolus) 6.889E-01 (USV1)

ABF1(1) AND SFF(1) AND PAC(1) => SimExpr(YDL063C) OR SimExpr(other) : 6 3

EXPR: (0.124) ABF1 (P < 0.000) SFF (P < 0.000) PAC (P < 0.037)

ORF SYMBOL P F C TF
YOL041C NOP12 rRNA metabolism ->
rRNA metabolism RNA binding ->
RNA binding nucleolus ->
nucleus GTS1, MET31
|YGR283C| NO SYMBOL ACE2, RAP1, SMP1
|YDR312W| SSF2 ribosomal large subunit assembly and maintenance, conjugation with cellular fusion ->
ribosome biogenesis and assembly, conjugation with cellular fusion rRNA binding ->
RNA binding nucleolus ->
nucleus ABF1, FKH2, INO4, RAP1
YJL069C UTP18 ABF1
YKL014C NO SYMBOL ABF1
YER110C KAP123 protein-nucleus import ->
intracellular protein transport, nucleocytoplasmic transport, protein metabolism protein carrier activity ->
protein carrier activity cytoplasm, nuclear pore, nucleus ->
cytoplasm, nucleus, integral to membrane, endomembrane system
YGR187C HGH1 ABF1, HAP3, HIR1, RCS1, RTG1
YDL063C NO SYMBOL HAL9, HAP2, MOT3
|YKL078W| DHR2 ribosome biogenesis ->
ribosome biogenesis and assembly RNA helicase activity ->
RNA binding nucleolus ->
nucleus ABF1
Main: ribosome biogenesis and assembly (0.50) RNA binding (0.75) nucleus (1.00) ABF1 (0.62)
Score: 0.17 0.50 1.00 0.393
P-value: 6.381E-01 (ribosome biogenesis and assembly) 1.473E-01 (RNA binding) 2.890E-02 (nucleolus) 2.023E-03 (ABF1)

ABF1(1) AND mRRPE(1) AND PAC(1) => SimExpr(YDL063C) OR SimExpr(other) : 8 2

EXPR: (0.122) ABF1 (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.023)

ORF SYMBOL P F C TF
YKL172W EBP2 rRNA processing ->
ribosome biogenesis, RNA processing, transcription from Pol I promoter nucleolus ->
nucleus ABF1, FZF1, RFX1
YJL069C UTP18 ABF1
YKL014C NO SYMBOL ABF1
YER110C KAP123 protein-nucleus import ->
protein targeting, nucleocytoplasmic transport protein carrier activity ->
protein carrier activity cytoplasm, nuclear pore, nucleus ->
cytoplasm, nucleus, integral to membrane, endomembrane system
|YPR010C| RPA135 transcription from Pol I promoter ->
transcription from Pol I promoter DNA-directed RNA polymerase activity ->
DNA-directed RNA polymerase activity DNA-directed RNA polymerase I complex ->
nucleus ROX1, SIG1
YGR187C HGH1 ABF1, HAP3, HIR1, RCS1, RTG1
YJL050W MTR4 35S primary transcript processing ->
ribosome biogenesis, RNA processing, transcription from Pol I promoter ATP dependent RNA helicase activity ->
RNA helicase activity, ATP dependent helicase activity, RNA dependent ATPase activity nucleolus ->
nucleus
YNL112W DBP2 RNA helicase activity ->
RNA helicase activity bud neck ->
site of polarized growth (sensu Fungi)
|YNR046W| NO SYMBOL ABF1
YDL063C NO SYMBOL HAL9, HAP2, MOT3
Main: transcription from Pol I promoter (0.75) RNA helicase activity (0.50) nucleus (0.80) ABF1 (0.71)
Score: 0.50 0.17 0.60 0.476
P-value: 8.012E-02 (transcription from Pol I promoter) 3.529E-02 (RNA helicase activity) 4.007E-02 (nucleolus) 3.060E-03 (ABF1)

ABF1(1) AND SFF(1) AND mRRPE(1) AND PAC(1) => SimExpr(YDL063C) : 5

EXPR: (0.095) ABF1 (P < 0.000) SFF (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.000)

ORF SYMBOL P F C TF
YJL069C UTP18 ABF1
YKL014C NO SYMBOL ABF1
YER110C KAP123 protein-nucleus import ->
protein-nucleus import protein carrier activity ->
protein carrier activity cytoplasm, nuclear pore, nucleus ->
cytoplasm, nuclear pore, nucleus
YGR187C HGH1 ABF1, HAP3, HIR1, RCS1, RTG1
YDL063C NO SYMBOL HAL9, HAP2, MOT3
Main: protein-nucleus import (1.00) protein carrier activity (1.00) nuclear pore (1.00) ABF1 (0.75)
Score: 0.00 0.00 0.00 0.500
P-value: 0.000E+00 0.000E+00 0.000E+00 2.194E-02 (ABF1)

mRRPE(1) AND PAC(1) => SimExpr(YKL172W) OR SimExpr(other) : 63 27

SFF(1) AND mRRPE(1) AND PAC(1) => SimExpr(YML093W) OR SimExpr(other) : 30 7

SFF(1) AND mRRPE(1) AND PAC(1) AND MCM1'(1) => SimExpr(YML093W) : 6

LYS14(1) AND mRRPE(1) AND PAC(1) => SimExpr(YHR052W) OR SimExpr(other) : 8 1

LYS14(1) AND SFF(1) AND mRRPE(1) AND PAC(1) => SimExpr(YHR052W) : 5

SFF'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YLR276C) OR SimExpr(other) : 36 11

SFF(1) AND BAS1(1) AND PAC(1) => SimExpr(YLR276C) OR SimExpr(other) : 5 2

EXPR: (0.124) SFF (P < 0.000) BAS1 (P < 0.000) PAC (P < 0.018)

ORF SYMBOL P F C TF
|YER115C| SPR6 sporulation (sensu Fungi) ->
sporulation (sensu Fungi) ARG80, RTG3
YOL022C NO SYMBOL MAC1, MOT3, RTS2
YCL059C KRR1 ribosome biogenesis, rRNA processing ->
ribosome biogenesis, rRNA processing nucleolus ->
nucleolus
YLR276C DBP9 ribosomal large subunit assembly and maintenance, 35S primary transcript processing ->
ribosomal subunit assembly, rRNA processing ATP dependent RNA helicase activity ->
ATP dependent RNA helicase activity nucleolus ->
nucleolus MATa1, RCS1, RTG3, SWI5
|YCR090C| NO SYMBOL
YBR104W YMC2 transport ->
transport transporter activity ->
transporter activity mitochondrial inner membrane ->
mitochondrial inner membrane FKH1, FKH2
YNR024W NO SYMBOL
Main: rRNA processing (0.50) ATP dependent RNA helicase activity (0.50) nucleolus (0.67) RTG3 (0.50)
Score: 0.17 0.00 0.33 0.167
P-value: 3.283E-01 (rRNA processing) 2.000E+00 1.871E-01 (nucleolus) 4.091E-02 (RTG3)

SFF(1) AND SFF'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YLR276C) OR SimExpr(other) : 27 7

EXPR: (0.130) SFF (P < 0.000) SFF' (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.000)

SFF(1) AND mRRPE(1) AND BAS1(1) AND PAC(1) => SimExpr(YLR276C) OR SimExpr(other) : 5 1

EXPR: (0.108) SFF (P < 0.000) mRRPE (P < 0.000) BAS1 (P < 0.000) PAC (P < 0.001)

ORF SYMBOL P F C TF
YOL022C NO SYMBOL MAC1, MOT3, RTS2
YCL059C KRR1 ribosome biogenesis, rRNA processing ->
ribosome biogenesis, rRNA processing nucleolus ->
nucleolus
YLR276C DBP9 ribosomal large subunit assembly and maintenance, 35S primary transcript processing ->
ribosomal subunit assembly, rRNA processing ATP dependent RNA helicase activity ->
ATP dependent RNA helicase activity nucleolus ->
nucleolus MATa1, RCS1, RTG3, SWI5
|YCR090C| NO SYMBOL
YBR104W YMC2 transport ->
transport transporter activity ->
transporter activity mitochondrial inner membrane ->
mitochondrial inner membrane FKH1, FKH2
YNR024W NO SYMBOL
Main: rRNA processing (0.67) ATP dependent RNA helicase activity (0.50) nucleolus (0.67) RTS2 (0.33)
Score: 0.33 0.00 0.33 0.000
P-value: 2.394E-01 (rRNA processing) 2.000E+00 1.373E-01 (nucleolus) 4.793E-01 (MATa1)

SFF'(1) AND mRRPE(1) AND BAS1(1) AND PAC(1) => SimExpr(YLR276C) OR SimExpr(other) : 5 1

EXPR: (0.108) SFF' (P < 0.000) mRRPE (P < 0.001) BAS1 (P < 0.000) PAC (P < 0.002)

ALPHA1'(1) AND SFF(1) AND mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YBR104W) : 5

EXPR: (0.113) ALPHA1' (P < 0.000) SFF (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.004) SCB (P < 0.000)

ORF SYMBOL P F C TF
YOR078W BUD21 processing of 20S pre-rRNA ->
rRNA processing snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleolus, ribonucleoprotein complex ABF1, MSS11, SIG1, SKO1
YJL109C UTP10 processing of 20S pre-rRNA ->
rRNA processing snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleolus, ribonucleoprotein complex
YCL059C KRR1 ribosome biogenesis, rRNA processing ->
ribosome biogenesis, rRNA processing nucleolus ->
nucleolus
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
rRNA processing, snRNA processing RNA binding ->
RNA binding nucleolus ->
nucleolus
YBR104W YMC2 transport ->
transport transporter activity ->
transporter activity mitochondrial inner membrane ->
mitochondrion, inner membrane FKH1, FKH2
Main: rRNA processing (0.80) RNA binding (0.75) nucleolus (0.80) ABF1 (0.50)
Score: 0.60 0.50 0.60 0.000
P-value: 8.613E-05 (rRNA processing) 3.111E-03 (snoRNA binding) 1.062E-04 (nucleolus) 3.159E-01 (SKO1)

SFF(1) AND BAS1(1) AND PAC(1) => SimExpr(YCL059C) OR SimExpr(other) : 5 2

mRRPE(1) AND BAS1(1) AND PAC(1) => SimExpr(YCL059C) OR SimExpr(other) : 6 1

EXPR: (0.111) mRRPE (P < 0.000) BAS1 (P < 0.000) PAC (P < 0.003)

ORF SYMBOL P F C TF
YOL022C NO SYMBOL MAC1, MOT3, RTS2
YCL059C KRR1 ribosome biogenesis, rRNA processing ->
ribosome biogenesis, rRNA processing nucleolus ->
nucleolus
YMR049C ERB1 rRNA processing ->
rRNA processing RTG3
YLR276C DBP9 ribosomal large subunit assembly and maintenance, 35S primary transcript processing ->
ribosomal subunit assembly, rRNA processing ATP dependent RNA helicase activity ->
ATP dependent RNA helicase activity nucleolus ->
nucleolus MATa1, RCS1, RTG3, SWI5
|YCR090C| NO SYMBOL
YBR104W YMC2 transport ->
transport transporter activity ->
transporter activity mitochondrial inner membrane ->
mitochondrial inner membrane FKH1, FKH2
YNR024W NO SYMBOL
Main: rRNA processing (0.75) ATP dependent RNA helicase activity (0.50) nucleolus (0.67) RTG3 (0.50)
Score: 0.50 0.00 0.33 0.167
P-value: 1.729E-02 (rRNA processing) 2.000E+00 1.871E-01 (nucleolus) 3.682E-02 (RTG3)

ALPHA1'(1) AND SFF'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YCL059C) OR SimExpr(other) : 24 5

ALPHA1'(1) AND SFF(1) AND mRRPE(1) AND PAC(1) => SimExpr(YCL059C) OR SimExpr(other) : 19 5

EXPR: (0.128) ALPHA1' (P < 0.000) SFF (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.000)

ALPHA1'(1) AND SFF(1) AND mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YCL059C) : 5

ALPHA1'(1) AND SFF'(1) AND mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YCL059C) : 7

ndt80(MSE)(1) AND PDR(1) => SimExpr(YCR045C) OR SimExpr(other) : 5 1

EXPR: (0.128) ndt80(MSE) (P < 0.000) PDR (P < 0.000)

ORF SYMBOL P F C TF
YBR159W NO SYMBOL ACE2, ARG81, GCR2, HIR2, LEU3, MOT3, PDR1, PHD1, SKN7, USV1
YDR317W NO SYMBOL HAL9, RLM1
YCR045C NO SYMBOL
|YKL096W| CWP1 cell wall organization and biogenesis ->
cell wall organization and biogenesis structural constituent of cell wall ->
structural constituent of cell wall cell wall (sensu Fungi) ->
cell wall (sensu Fungi) RLM1, SMP1, STE12, SWI4
YMR252C NO SYMBOL SKN7
YDR281C PHM6 PHO4, SUM1
Main: cell wall organization and biogenesis (1.00) structural constituent of cell wall (1.00) cell wall (sensu Fungi) (1.00) RLM1 SKN7 (0.40)
Score: 0.00 0.00 0.00 0.200
P-value: 0.000E+00 0.000E+00 0.000E+00 1.236E-01 (RLM1)

MCB(1) AND PAC(1) => SimExpr(YPR144C) OR SimExpr(other) : 5 2

mRRPE(1) AND STE12(1) AND PAC(1) => SimExpr(YBR247C) : 5

EXPR: (0.108) mRRPE (P < 0.000) STE12 (P < 0.000) PAC (P < 0.003)

ORF SYMBOL P F C TF
YNL308C KRI1 ribosome biogenesis ->
cell growth and/or maintenance nucleolus ->
nucleolus
YJL069C UTP18 ABF1
YBR247C ENP1 processing of 20S pre-rRNA, rRNA processing, cell growth and/or maintenance ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism snoRNA binding ->
snoRNA binding nucleolus, nucleus ->
nucleolus, nucleus
YMR310C NO SYMBOL
YAL059W ECM1 cell wall organization and biogenesis ->
cell growth and/or maintenance MOT3
Main: cell growth and/or maintenance (1.00) snoRNA binding (1.00) nucleolus (1.00) ABF1 (0.50)
Score: 1.00 0.00 1.00 0.000
P-value: 1.419E-01 (ribosome biogenesis) 0.000E+00 9.406E-02 (nucleolus) 1.688E-01 (MOT3)

AVERAGE SCORES:

P
  SCORE: 0.661 (Part of genes covered by "Main": 0.771) (No. rules=51/53)
  P-VALUE: 0.667
F
  SCORE: 0.337 (Part of genes covered by "Main": 0.567) (No. rules=43/53)
  P-VALUE: 0.512
C
  SCORE: 0.697 (Part of genes covered by "Main": 0.817) (No. rules=50/53)
  P-VALUE: 0.600
TF
  SCORE: 0.285 (Part of genes covered by "Main": 0.481) (No. rules=49/53)
  P-VALUE: 0.388
EXPRESSION: 0.962 (53)

ORF	SYMBOL	P	F	C	TF
YGR280C	PXR1	35S primary transcript processing, snRNA processing -> cytoplasm organization and biogenesis, RNA metabolism, transcription	RNA binding -> RNA binding	nucleolus -> nucleus
\|YJL138C\|	TIF2	translational initiation, regulation of translational initiation -> macromolecule biosynthesis, protein metabolism	translation initiation factor activity, RNA helicase activity -> translation factor activity\, nucleic acid binding, RNA binding	ribosome, cytoplasm -> cytoplasm, ribonucleoprotein complex	PHD1
\|YMR259C\|	NO SYMBOL				ARG80, GCR2, GTS1, HIR1, SRD1
YHR052W	CIC1	protein catabolism -> macromolecule catabolism, protein metabolism	protein binding\, bridging -> protein binding\, bridging	nucleolus, proteasome complex (sensu Eukarya) -> nucleus, cytoplasm	HAP4, MATa1
YOR078W	BUD21	processing of 20S pre-rRNA -> cytoplasm organization and biogenesis, RNA metabolism, transcription	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	ABF1, MSS11, SIG1, SKO1
YBR104W	YMC2	transport -> transport	transporter activity -> transporter activity	mitochondrial inner membrane -> cytoplasm, inner membrane	FKH1, FKH2
YJL109C	UTP10	processing of 20S pre-rRNA -> cytoplasm organization and biogenesis, RNA metabolism, transcription	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex
YJL069C	UTP18				ABF1
YCL059C	KRR1	ribosome biogenesis, rRNA processing -> cytoplasm organization and biogenesis, RNA metabolism, transcription		nucleolus -> nucleus
\|YLR249W\|	YEF3	translational elongation -> macromolecule biosynthesis, protein metabolism	translation elongation factor activity -> translation factor activity\, nucleic acid binding	ribosome -> cytoplasm, ribonucleoprotein complex	INO2, INO4
Main:		RNA metabolism (0.50)	RNA binding (0.57)	nucleus (0.62)	ABF1 (0.29)
Score:		0.32	0.33	0.71	0.048
P-value:		3.912E-03 (rRNA processing)	1.827E-02 (snoRNA binding)	2.304E-04 (nucleolus)	1.000E+00

ORF	SYMBOL	P	F	C	TF
YER177W	BMH1	pseudohyphal growth, sporulation (sensu Saccharomyces), RAS protein signal transduction, activation of MAPK (pseudohyphal growth), glycogen metabolism -> cell organization and biogenesis, sporulation, carbohydrate metabolism, signal transduction, energy derivation by oxidation of organic compounds	DNA binding -> DNA binding	nucleus -> nucleus	ACE2, GCR1, MBP1, NDD1, SWI4, SWI5
YGR254W	ENO1	gluconeogenesis, glycolysis -> alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism	phosphopyruvate hydratase activity -> hydro-lyase activity	phosphopyruvate hydratase complex, cytoplasm -> cytoplasm	FKH2, MSN4, PDR1, SWI5, YAP5
YNL241C	ZWF1	pentose-phosphate shunt -> coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism	glucose-6-phosphate 1-dehydrogenase activity -> oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor	cytoplasm -> cytoplasm	ACE2, ADR1, FKH2, HIR1, IME4, MBP1, NDD1, PHO4, RCS1, SFP1, SKN7, SWI5
YJL052W	TDH1	gluconeogenesis, glycolysis -> alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism	glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) activity -> oxidoreductase activity\, acting on the aldehyde or oxo group of donors\, NAD or NADP as acceptor	cytosol, lipid particle, cell wall -> cytoplasm, cell wall	MAC1
YOR374W	ALD4	ethanol metabolism -> alcohol metabolism	aldehyde dehydrogenase (NAD+) activity -> oxidoreductase activity\, acting on the aldehyde or oxo group of donors\, NAD or NADP as acceptor	mitochondrion -> cytoplasm	RAP1
Main:		alcohol metabolism (0.80)	oxidoreductase activity\, acting on the aldehyde or oxo group of donors\, NAD or NADP as acceptor (0.40)	cytoplasm (0.80)	SWI5 (0.60)
Score:		0.90	0.10	0.60	0.300
P-value:		1.748E-04 (monosaccharide catabolism)	3.111E-03 (oxidoreductase activity\, acting on the aldehyde or oxo group of donors\, NAD or NADP as acceptor)	5.952E-01 (cytosol)	2.493E-03 (SWI5)

ORF	SYMBOL	P	F	C	TF
\|YIL026C\|	IRR1	mitotic sister chromatid cohesion, colony morphology, germination (sensu Saccharomyces), cytogamy -> cell organization and biogenesis, sporulation, plasma membrane fusion, sporulation (sensu Fungi), cell proliferation, conjugation, sexual reproduction	protein binding -> protein binding	nuclear cohesin complex -> chromosome, nucleus	ABF1, MAL33, MBP1, SWI6
YPR144C	NOC4	ribosome biogenesis -> cell organization and biogenesis		nucleus -> nucleus	HIR1
YLR049C	NO SYMBOL				MBP1, SWI5
YIL066C	RNR3	DNA replication -> cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ribonucleoside-diphosphate reductase activity -> ribonucleoside-diphosphate reductase activity	cytoplasm -> cytoplasm	RFX1, STB1
YDR279W	RNH202				GCR2, MBP1, RIM101, RLM1, SWI6, THI2
YOR284W	HUA2				RFX1, YAP6
\|YJR055W\|	HIT1	aerobic respiration -> energy pathways			STP2
Main:		cell organization and biogenesis (0.50)	ribonucleoside-diphosphate reductase activity (0.50)	nucleus (0.67)	MBP1 (0.43)
Score:		0.33	0.00	0.33	0.190
P-value:		5.867E-01 (DNA replication and chromosome cycle)	2.000E+00	3.799E+00 (nucleus)	1.050E-02 (MBP1)

ORF	SYMBOL	P	F	C	TF
YNR053C	NOG2	mRNA splicing -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	GTPase activity -> purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleus, nucleolus, nucleoplasm -> nucleus, nucleoplasm	ABF1, AZF1
\|YMR049C\|	ERB1	rRNA processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism			RTG3
YGR280C	PXR1	35S primary transcript processing, snRNA processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	RNA binding -> RNA binding	nucleolus -> nucleus
YOR310C	NOP58	rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription		small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	ABF1, SWI6
YML093W	UTP14	processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex
YHR196W	UTP9	processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex, nucleolus, nucleus -> nucleus, ribonucleoprotein complex
YGL171W	ROK1	35S primary transcript processing, mRNA splicing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ATP dependent RNA helicase activity, ATPase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleolus -> nucleus	RGT1
YDR184C	ATC1	response to stress, polar budding -> response to stress, asexual reproduction		nucleus -> nucleus	ARO80, GLN3, SIP4, SKO1
YJR070C	NO SYMBOL				GAT3, YAP5
YNL308C	KRI1	ribosome biogenesis -> cell growth and/or maintenance		nucleolus -> nucleus
YGL029W	CGR1	ribosome biogenesis, rRNA processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism		nucleolus -> nucleus
YLR276C	DBP9	ribosomal large subunit assembly and maintenance, 35S primary transcript processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ATP dependent RNA helicase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleolus -> nucleus	MATa1, RCS1, RTG3, SWI5
\|YNL112W\|	DBP2		RNA helicase activity -> RNA binding	bud neck -> site of polarized growth (sensu Fungi)
YDR279W	RNH202				GCR2, MBP1, RIM101, RLM1, SWI6, THI2
YDR496C	PUF6				RFX1
YGL169W	SUA5	cell growth and/or maintenance -> cell growth and/or maintenance			ABF1
YOR272W	YTM1	chromosome organization and biogenesis (sensu Eukarya), ribosomal large subunit biogenesis -> cell growth and/or maintenance		nucleus, nucleolus -> nucleus	LEU3, PUT3, REB1
\|YOR359W\|	VTS1	protein-vacuolar targeting -> protein metabolism, cell growth and/or maintenance	intracellular transporter activity -> transporter activity	cytosol -> cytoplasm	RAP1
YLR002C	NOC3	DNA replication initiation, rRNA processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription	chromatin binding, protein binding -> DNA binding, protein binding	nucleus, nucleolus -> nucleus	HIR1, IXR1, RCS1
\|YGR162W\|	TIF4631	translational initiation -> biosynthesis, protein metabolism	translation initiation factor activity -> translation factor activity\, nucleic acid binding	ribosome -> cytoplasm, ribonucleoprotein complex	HSF1
\|YOR095C\|	RKI1	pentose-phosphate shunt -> coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism	ribose-5-phosphate isomerase activity -> intramolecular isomerase activity		FHL1, FKH2, RAP1
YHR169W	DBP8	35S primary transcript processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ATP dependent RNA helicase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleolus -> nucleus
\|YNL175C\|	NOP13		RNA binding -> RNA binding	nucleolus, nucleoplasm -> nucleus	INO2, INO4
\|YPR183W\|	DPM1	N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis -> lipid biosynthesis, biosynthesis, membrane lipid metabolism, protein metabolism, lipoprotein metabolism	transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity -> transferase activity\, transferring glycosyl groups	endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network -> cytoplasm, endomembrane system	SWI5
\|YHR128W\|	FUR1	pyrimidine salvage -> biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	uracil phosphoribosyltransferase activity -> transferase activity\, transferring glycosyl groups		CIN5
\|YCR090C\|	NO SYMBOL
YNL132W	KRE33
YOR078W	BUD21	processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	ABF1, MSS11, SIG1, SKO1
YMR229C	RRP5	rRNA processing, processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	RNA binding, snoRNA binding -> RNA binding	nucleolus, nucleolus organizer complex -> nucleus	FHL1, RAP1
YGR245C	SDA1	actin cytoskeleton organization and biogenesis, start control point of mitotic cell cycle -> cell growth and/or maintenance		nucleus -> nucleus
YOL022C	NO SYMBOL				MAC1, MOT3, RTS2
\|YFR001W\|	LOC1	ribosomal large subunit biogenesis -> cell growth and/or maintenance	mRNA binding -> RNA binding	nucleus -> nucleus	ARG80, GAL4, GTS1, HAP4, HIR1, LEU3, MSN2, MSN4, RCS1, RLM1, SWI4
YBR104W	YMC2	transport -> cell growth and/or maintenance	transporter activity -> transporter activity	mitochondrial inner membrane -> cytoplasm, inner membrane	FKH1, FKH2
YER082C	UTP7	processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	CHA4
YJL109C	UTP10	processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex
YNR024W	NO SYMBOL
YKL014C	NO SYMBOL				ABF1
\|YER110C\|	KAP123	protein-nucleus import -> protein metabolism, cell growth and/or maintenance	protein carrier activity -> protein binding	cytoplasm, nuclear pore, nucleus -> cytoplasm, nucleus, integral to membrane, endomembrane system
YCL059C	KRR1	ribosome biogenesis, rRNA processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism		nucleolus -> nucleus
YNL075W	IMP4	rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription	rRNA primary transcript binding -> RNA binding	small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	USV1
YCR072C	NO SYMBOL				YFL044C
YAL059W	ECM1	cell wall organization and biogenesis -> cell growth and/or maintenance			MOT3
YGL099W	LSG1	conjugation with cellular fusion, sporulation (sensu Saccharomyces), ribosome nucleus export -> conjugation, protein metabolism, cell growth and/or maintenance, sexual reproduction	GTPase activity -> purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	cytoplasm -> cytoplasm	PHO4
YCR016W	NO SYMBOL
YJL033W	HCA4	35S primary transcript processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ATP dependent RNA helicase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleolus -> nucleus	HIR2, USV1
\|YPR010C\|	RPA135	transcription from Pol I promoter -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	DNA-directed RNA polymerase activity -> transferase activity\, transferring phosphorus-containing groups	DNA-directed RNA polymerase I complex -> nucleus	ROX1, SIG1
YDR449C	UTP6	processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	FHL1, GAT3, HIR2, RAP1, RGM1, YAP5
YLR222C	UTP13	processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	ABF1
Main:		cell growth and/or maintenance (0.81)	RNA binding (0.61)	nucleus (0.82)	ABF1 (0.18)
Score:		0.75	0.39	0.71	0.068
P-value:		4.375E-19 (ribosome biogenesis)	6.431E-09 (snoRNA binding)	7.397E-20 (nucleolus)	1.000E+00

ORF	SYMBOL	P	F	C	TF
YCL024W	KCC4	septin checkpoint, protein amino acid phosphorylation, bud growth, axial budding, septin ring assembly -> cell cycle, phosphate metabolism, budding, septin ring assembly, protein modification	protein kinase activity -> protein kinase activity	bud neck -> bud neck	ASH1, CIN5, DAL81, HSF1, MET4, PHD1, RAP1, STP1, STP2
\|YMR102C\|	NO SYMBOL
YNR028W	CPR8		peptidyl-prolyl cis-trans isomerase activity -> peptidyl-prolyl cis-trans isomerase activity		ASH1, DIG1, MCM1
YCR065W	HCM1	spindle assembly, transcription initiation from Pol II promoter -> cytoplasm organization and biogenesis, cell cycle, transcription	specific RNA polymerase II transcription factor activity -> specific RNA polymerase II transcription factor activity	nucleus -> nucleus	ASH1, HSF1, MBP1, NDD1, PHD1, ROX1, STB1, SWI4
YDR507C	GIN4	septin checkpoint, protein amino acid phosphorylation, bud growth, axial budding, septin ring assembly -> cell cycle, phosphate metabolism, budding, septin ring assembly, protein modification	protein kinase activity -> protein kinase activity	bud neck -> bud neck	GRF10(Pho2), GTS1, MBP1, MCM1, SWI4, SWI6
\|YGR189C\|	CRH1			cell wall, incipient bud site -> cell wall, incipient bud site	GRF10(Pho2), MBP1, RLM1, STE12, SWI4, SWI5
YML027W	YOX1	negative regulation of transcription from Pol II promoter\, mitotic, regulation of mitotic cell cycle -> regulation of transcription, M phase, transcription, cell cycle	specific transcriptional repressor activity, DNA binding -> specific transcriptional repressor activity, DNA binding	nucleus -> nucleus	MBP1, SWI4, SWI6
Main:		cell cycle (1.00)	protein kinase activity (0.40)	nucleus (0.40)	SWI4 MBP1 (0.67)
Score:		1.00	0.10	0.20	0.667
P-value:		3.093E-04 (septin checkpoint)	3.615E-01 (protein kinase activity)	1.114E-01 (bud neck)	4.457E-04 (ASH1)

ORF	SYMBOL	P	F	C	TF
YKR077W	NO SYMBOL
\|YLR049C\|	NO SYMBOL				MBP1, SWI5
YDR134C	NO SYMBOL				ASH1, NRG1, SOK2, SWI4
\|YJR030C\|	NO SYMBOL				MBP1, PHO4, RTG1, SWI6
\|YER132C\|	PMD1	sporulation -> sporulation			SMP1
YPR185W	APG13	protein-vacuolar targeting, autophagy -> organelle organization and biogenesis, autophagy, intracellular protein transport, protein metabolism	protein binding -> protein binding	extrinsic to membrane -> extrinsic to membrane	MET4, SWI6
YFR027W	ECO1	sister chromatid cohesion, DNA replication, DNA repair -> DNA replication and chromosome cycle, DNA repair, mitotic cell cycle, DNA metabolism	acetyltransferase activity -> acetyltransferase activity	nuclear chromatin -> chromosome, nucleus
YMR076C	PDS5	mitotic sister chromatid cohesion, mitotic chromosome condensation -> DNA replication and chromosome cycle, M phase, mitotic cell cycle	structural molecule activity -> structural molecule activity	condensed nuclear chromosome -> chromosome, nucleus	FKH2, MBP1, SWI6
YML027W	YOX1	negative regulation of transcription from Pol II promoter\, mitotic, regulation of mitotic cell cycle -> mitotic cell cycle, M phase, regulation of transcription, nuclear division, transcription\, DNA-dependent, regulation of cell cycle	specific transcriptional repressor activity, DNA binding -> specific transcriptional repressor activity, DNA binding	nucleus -> nucleus	MBP1, SWI4, SWI6
YMR179W	SPT21	regulation of transcription from Pol II promoter -> regulation of transcription, transcription\, DNA-dependent			MBP1, STB1, SWI4, SWI6, UGA3
Main:		mitotic cell cycle (0.50)	DNA binding (0.25)	nucleus (0.75)	MBP1 SWI6 (0.62)
Score:		0.27	0.00	0.50	0.571
P-value:		1.053E-02 (sister chromatid cohesion)	2.575E+00 (binding)	2.915E-01 (nuclear chromosome)	4.452E-05 (SWI6)

ORF	SYMBOL	P	F	C	TF
YDR309C	GIC2	axial budding, Rho protein signal transduction, establishment of cell polarity (sensu Saccharomyces) -> asexual reproduction, signal transduction, cell organization and biogenesis	small GTPase regulatory/interacting protein activity -> small GTPase regulatory/interacting protein activity	actin cap (sensu Saccharomyces), bud tip, shmoo tip, incipient bud site -> cell cortex, site of polarized growth (sensu Fungi), incipient bud site, cytoplasm	ASH1, HSF1, MBP1, PHD1, RLM1, SKN7, STB1, STE12, SWI4, SWI6
\|YHR023W\|	MYO1	cytokinesis, response to osmotic stress, axial budding -> cell proliferation, response to abiotic stimulus, asexual reproduction	microfilament motor activity -> microfilament motor activity	contractile ring (sensu Saccharomyces) -> site of polarized growth (sensu Fungi), cell cortex, cytoplasm
YKR013W	PRY2				SWI4, SWI6
YNL053W	MSG5	adaptation to pheromone during conjugation with cellular fusion -> conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus	prenylated protein tyrosine phosphatase activity -> prenylated protein tyrosine phosphatase activity		DIG1, FKH1, MCM1
YJL157C	FAR1	signal transduction during conjugation with cellular fusion, cell cycle arrest -> signal transduction, cell proliferation, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus	cyclin-dependent protein kinase inhibitor activity -> cyclin-dependent protein kinase inhibitor activity	cytoplasm, nucleus -> cytoplasm, nucleus	MCM1
YGR146C	NO SYMBOL				HSF1
\|YAR018C\|	KIN3	chromosome segregation -> cell proliferation	protein kinase activity -> protein kinase activity		FKH2, MCM1, MSS11, NDD1
YHR005C	GPA1	signal transduction during conjugation with cellular fusion -> signal transduction, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus	heterotrimeric G-protein GTPase activity -> heterotrimeric G-protein GTPase activity	heterotrimeric G-protein complex, plasma membrane -> extrinsic to membrane, plasma membrane	DIG1, IXR1, MCM1, PHD1, SOK2, STE12
Main:		response to abiotic stimulus (0.67)	heterotrimeric G-protein GTPase activity (0.17)	cytoplasm (0.75)	MCM1 (0.57)
Score:		0.73	0.00	0.50	0.429
P-value:		2.435E-04 (reproduction)	1.759E+00 (hydrolase activity)	2.090E-01 (cell cortex)	1.848E-03 (MCM1)

ORF	SYMBOL	P	F	C	TF
YLR344W	RPL26A	protein biosynthesis -> protein biosynthesis	RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytosol, ribosome	FHL1, RAP1
YOR369C	RPS12	protein biosynthesis -> protein biosynthesis	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> cytosol, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome	ARG80, FHL1, FKH2, LEU3, NDD1, PDR1, RME1, SMP1, YAP6
YBL087C	RPL23A	protein biosynthesis -> protein biosynthesis	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytosol, ribosome	FHL1, IXR1, MSS11, PDR1, RAP1, SMP1, SOK2
YMR194W	RPL36A	protein biosynthesis -> protein biosynthesis	RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytosol, ribosome	ARG80, ARO80, BAS1, CUP9, FHL1, HAL9, HAP4, HAP5, HMS1, MET31, NRG1, RAP1, RCS1, RME1, STP2
YLR249W	YEF3	translational elongation -> protein biosynthesis	translation elongation factor activity -> translation elongation factor activity	ribosome -> ribosome	INO2, INO4
Main:		protein biosynthesis (1.00)	structural constituent of ribosome (0.80)	ribosome (1.00)	FHL1 (0.80)
Score:		1.00	0.60	1.00	0.600
P-value:		1.576E-04 (protein biosynthesis)	5.237E-04 (structural constituent of ribosome)	4.219E-05 (ribosome)	1.522E-04 (FHL1)

ORF	SYMBOL	P	F	C	TF
YGL197W	MDS3	sporulation -> sporulation		cytoplasm -> cytoplasm	MTH1
YOR153W	PDR5	drug transport, response to drug -> transport, response to abiotic stimulus	xenobiotic-transporting ATPase activity -> xenobiotic-transporting ATPase activity	plasma membrane -> plasma membrane	YAP6
YER062C	HOR2	carbohydrate metabolism, response to osmotic stress, glycerol biosynthesis -> carbohydrate metabolism, response to abiotic stimulus, alcohol metabolism, energy derivation by oxidation of organic compounds, glycerol ether metabolism, lipid metabolism, biosynthesis	glycerol-1-phosphatase activity -> glycerol-1-phosphatase activity		MTH1
\|YDR226W\|	ADK1	cell proliferation -> cell proliferation	adenylate kinase activity -> adenylate kinase activity	cytoplasm, mitochondrial intermembrane space -> cytoplasm	PUT3
\|YDL048C\|	STP4				HIR2
YOR273C	TPO4	polyamine transport -> transport	spermine transporter activity, spermidine transporter activity -> spermine transporter activity, spermidine transporter activity	plasma membrane, vacuolar membrane -> plasma membrane, cytoplasm	ARO80, BAS1, FZF1, HIR1, IME4, NRG1, PDR1, PHO4, SFP1, SKN7, STP1
YLR121C	YPS3	protein metabolism -> protein metabolism	aspartic-type endopeptidase activity -> aspartic-type endopeptidase activity	plasma membrane -> plasma membrane	CIN5, SWI4, YAP6
Main:		response to abiotic stimulus (0.33)	adenylate kinase activity (0.20)	cytoplasm (0.60)	MTH1 YAP6 (0.29)
Score:		0.13	0.00	0.60	0.095
P-value:		3.758E-01 (response to abiotic stimulus)	5.825E-01 (hydrolase activity)	8.418E-02 (plasma membrane)	1.381E-01 (MTH1)

ORF	SYMBOL	P	F	C	TF
YMR049C	ERB1	rRNA processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism			RTG3
YGR280C	PXR1	35S primary transcript processing, snRNA processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	RNA binding -> RNA binding	nucleolus -> nucleus
YML125C	NO SYMBOL				MAL13, MSN4, NDD1, RME1, SWI5
YOR310C	NOP58	rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription		small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	ABF1, SWI6
YML093W	UTP14	processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex
\|YBR267W\|	NO SYMBOL
YPL043W	NOP4	rRNA processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	RNA binding -> RNA binding	nucleolus -> nucleus
YGL029W	CGR1	ribosome biogenesis, rRNA processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism		nucleolus -> nucleus
\|YDR279W\|	RNH202				GCR2, MBP1, RIM101, RLM1, SWI6, THI2
YGL169W	SUA5	cell growth and/or maintenance -> cell growth and/or maintenance			ABF1
YOR095C	RKI1	pentose-phosphate shunt -> coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism	ribose-5-phosphate isomerase activity -> intramolecular isomerase activity		FHL1, FKH2, RAP1
\|YIL122W\|	POG1	re-entry into mitotic cell cycle after pheromone arrest -> cell growth and/or maintenance, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus	specific RNA polymerase II transcription factor activity -> specific RNA polymerase II transcription factor activity	nucleus -> nucleus	ASH1, CIN5, NRG1, RLM1, SMP1, YAP6
\|YHR128W\|	FUR1	pyrimidine salvage -> biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	uracil phosphoribosyltransferase activity -> transferase activity\, transferring glycosyl groups		CIN5
YER082C	UTP7	processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	CHA4
YCR016W	NO SYMBOL
\|YDR399W\|	HPT1	purine nucleotide biosynthesis -> biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	hypoxanthine phosphoribosyltransferase activity -> transferase activity\, transferring glycosyl groups
YGR159C	NSR1	ribosomal small subunit assembly and maintenance, rRNA processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	single-stranded DNA binding, RNA binding -> DNA binding, RNA binding	nucleolus, nucleus -> nucleus
YDR365C	NO SYMBOL				ABF1, MSS11, YJL206C
Main:		cell growth and/or maintenance (0.77)	RNA binding (0.56)	nucleus (1.00)	ABF1 (0.30)
Score:		0.79	0.31	1.00	0.133
P-value:		5.573E-07 (rRNA processing)	4.411E-02 (transferase activity\, transferring pentosyl groups)	2.809E-05 (nucleolus)	1.000E+00

ORF	SYMBOL	P	F	C	TF
YPL131W	RPL5	protein biosynthesis, ribosomal large subunit assembly and maintenance -> protein biosynthesis, ribosome biogenesis and assembly	RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytosol, ribosome	FHL1, GAT3, RAP1
\|YPR080W\|	TEF1	translational elongation -> protein biosynthesis	translation elongation factor activity -> translation elongation factor activity	ribosome -> ribosome	FHL1, PDR1, RAP1, YAP5
YGR085C	RPL11B	protein biosynthesis, ribosomal large subunit assembly and maintenance -> protein biosynthesis, ribosome biogenesis and assembly	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytosol, ribosome	FHL1, MIG1
YLR249W	YEF3	translational elongation -> protein biosynthesis	translation elongation factor activity -> translation elongation factor activity	ribosome -> ribosome	INO2, INO4
YBL087C	RPL23A	protein biosynthesis -> protein biosynthesis	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytosol, ribosome	FHL1, IXR1, MSS11, PDR1, RAP1, SMP1, SOK2
YHL033C	RPL8A	protein biosynthesis -> protein biosynthesis	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytosol, ribosome	FHL1
Main:		protein biosynthesis (1.00)	structural constituent of ribosome (0.67)	ribosome (1.00)	FHL1 (0.83)
Score:		1.00	0.47	1.00	0.667
P-value:		3.792E-05 (protein biosynthesis)	1.921E-03 (structural constituent of ribosome)	3.416E-06 (ribosome)	2.721E-06 (FHL1)

ORF	SYMBOL	P	F	C	TF
\|YKL072W\|	STB6				ARG81, ARO80, BAS1, CIN5, GCN4, GLN3, HAP3, MCM1, PHD1, REB1, RLM1, YJL206C, ZAP1
YDL130W	RPP1B	protein biosynthesis, translational elongation -> protein biosynthesis	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, GAL4, RAP1, RFX1
YMR116C	ASC1			cytoplasm -> cytoplasm	FHL1, RAP1
YMR013C	SEC59	protein-ER targeting, protein amino acid glycosylation -> organelle organization and biogenesis, protein biosynthesis, intracellular protein transport, secretory pathway, protein modification, glycoprotein metabolism, protein metabolism	dolichol kinase activity -> dolichol kinase activity	membrane -> membrane	FHL1, NDD1, RAP1, RLM1, RME1
\|YPR080W\|	TEF1	translational elongation -> protein biosynthesis	translation elongation factor activity -> translation elongation factor activity	ribosome -> cytoplasm, ribonucleoprotein complex	FHL1, PDR1, RAP1, YAP5
YLR249W	YEF3	translational elongation -> protein biosynthesis	translation elongation factor activity -> translation elongation factor activity	ribosome -> cytoplasm, ribonucleoprotein complex	INO2, INO4
YBR048W	RPS11B	protein biosynthesis, ribosomal small subunit assembly and maintenance, regulation of translational fidelity -> ribosome biogenesis and assembly, protein biosynthesis	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	GAL4, HAP4, LEU3, MET31, MSN1
Main:		protein biosynthesis (1.00)	translation elongation factor activity (0.40)	cytoplasm (0.83)	RAP1 FHL1 (0.57)
Score:		1.00	0.20	0.67	0.381
P-value:		9.360E-05 (translational elongation)	4.519E-03 (translation elongation factor activity)	1.212E-02 (ribosome)	1.050E-03 (FHL1)

ORF	SYMBOL	P	F	C	TF
\|YBR295W\|	PCA1	copper ion homeostasis -> cell homeostasis	P-type ATPase activity -> ATPase activity\, coupled to transmembrane movement of substances, P-P-bond-hydrolysis-driven transporter activity, cation transporter activity	membrane -> membrane	GAL4, SMP1
YKL006W	RPL14A	protein biosynthesis -> biosynthesis, protein metabolism	RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, GAT3, GRF10(Pho2), GTS1, RAP1
YJL217W	NO SYMBOL				CIN5, MAC1, PHD1, SWI5, YAP6
YOR312C	RPL20B	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, FKH2, GAT3, RAP1
YLR344W	RPL26A	protein biosynthesis -> biosynthesis, protein metabolism	RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, RAP1
YJR145C	RPS4A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya), cytoplasm -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	ACE2, CIN5, FHL1, INO4, MTH1, RAP1, YAP6
\|YDR406W\|	PDR15	transport -> transport	ATP-binding cassette (ABC) transporter activity -> ATPase activity\, coupled to transmembrane movement of substances, P-P-bond-hydrolysis-driven transporter activity	integral to membrane -> membrane
\|YDL184C\|	RPL41A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, HAL9, HMS1, MAC1, MSS11, RAP1, RME1, SIG1
YLR441C	RPS1A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	FHL1, GAT3, RAP1, YAP5
YGL115W	SNF4	regulation of transcription from Pol II promoter, peroxisome organization and biogenesis -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	protein kinase activator activity -> protein kinase activator activity	plasma membrane, nucleus, cytoplasm -> membrane, nucleus, cytoplasm	BAS1, CAD1, MAC1, NRG1, PDR1, RAP1, SMP1, YAP5
YLR249W	YEF3	translational elongation -> biosynthesis, protein metabolism	translation elongation factor activity -> translation elongation factor activity	ribosome -> cytoplasm, ribonucleoprotein complex	INO2, INO4
\|YLR452C\|	SST2	signal transduction, adaptation to pheromone during conjugation with cellular fusion -> signal transduction, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus	GTPase activator activity -> GTPase activator activity	plasma membrane -> membrane	DIG1, FHL1, RAP1, STE12
YOR369C	RPS12	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	ARG80, FHL1, FKH2, LEU3, NDD1, PDR1, RME1, SMP1, YAP6
YNL069C	RPL16B	protein biosynthesis -> biosynthesis, protein metabolism	RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, GAT3, PDR1, RAP1, RGM1, YAP5
YBL087C	RPL23A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, IXR1, MSS11, PDR1, RAP1, SMP1, SOK2
\|YKR092C\|	SRP40	nucleocytoplasmic transport -> transport	chaperone activity -> chaperone activity	nucleolus -> nucleus	CUP9, MET4, RAP1
YMR194W	RPL36A	protein biosynthesis -> biosynthesis, protein metabolism	RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	ARG80, ARO80, BAS1, CUP9, FHL1, HAL9, HAP4, HAP5, HMS1, MET31, NRG1, RAP1, RCS1, RME1, STP2
\|YBR098W\|	MMS4	DNA repair, meiotic recombination -> cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	transcription co-activator activity, endonuclease activity -> transcription co-activator activity, endonuclease activity	nucleus -> nucleus
YER074W	RPS24A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	FHL1, GAT3, PDR1, RAP1, RGM1, SMP1, YAP5
Main:		biosynthesis (0.67)	structural constituent of ribosome (0.61)	cytoplasm (0.72)	RAP1 (0.76)
Score:		0.44	0.37	0.57	0.728
P-value:		1.235E-06 (protein biosynthesis)	5.371E-08 (structural constituent of ribosome)	2.035E-09 (cytosolic ribosome (sensu Eukarya))	1.901E-12 (FHL1)

ORF	SYMBOL	P	F	C	TF
YNL082W	PMS1	mismatch repair, meiosis -> DNA metabolism, cell proliferation	ATPase activity, ATP binding, DNA binding -> ATP binding, DNA binding, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides	nuclear chromosome -> intracellular	MTH1
\|YOR284W\|	HUA2				RFX1, YAP6
YJL095W	BCK1	protein amino acid phosphorylation, protein kinase cascade, response to nutrients, establishment of cell polarity (sensu Saccharomyces) -> phosphorus metabolism, signal transduction, response to extracellular stimulus, cell organization and biogenesis, protein metabolism, response to abiotic stimulus	MAP kinase kinase kinase activity -> protein kinase activity	intracellular -> intracellular	YAP1
YPR185W	APG13	protein-vacuolar targeting, autophagy -> cell organization and biogenesis, autophagy, protein metabolism, transport	protein binding -> protein binding	extrinsic to membrane -> extrinsic to membrane	MET4, SWI6
YOR144C	ELG1	negative regulation of DNA transposition, negative regulation of DNA recombination -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism			YJL206C
YCR065W	HCM1	spindle assembly, transcription initiation from Pol II promoter -> cell organization and biogenesis, cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	specific RNA polymerase II transcription factor activity -> specific RNA polymerase II transcription factor activity	nucleus -> intracellular	ASH1, HSF1, MBP1, NDD1, PHD1, ROX1, STB1, SWI4
YFR027W	ECO1	sister chromatid cohesion, DNA replication, DNA repair -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, cell proliferation	acetyltransferase activity -> acyltransferase activity	nuclear chromatin -> intracellular
\|YER047C\|	SAP1				MSS11
\|YPL140C\|	MKK2	protein amino acid phosphorylation, signal transduction -> phosphorus metabolism, signal transduction, protein metabolism	MAP kinase kinase activity -> protein kinase activity	intracellular -> intracellular	FKH1, FKH2
Main:		cell organization and biogenesis (0.43)	protein kinase activity (0.33)	intracellular (0.83)	SWI4 (0.12)
Score:		0.48	0.07	0.67	0.000
P-value:		6.497E-01 (DNA replication)	5.827E-01 (protein kinase activity)	2.383E-01 (nuclear chromosome)	1.000E+00

ORF	SYMBOL	P	F	C	TF
YGR158C	MTR3	35S primary transcript processing, mRNA catabolism -> cell organization and biogenesis, catabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	3'-5' exoribonuclease activity -> hydrolase activity\, acting on ester bonds, RNA binding	nuclear exosome (RNase complex), cytoplasmic exosome (RNase complex) -> exosome (RNase complex), cytoplasm, nucleus	ZMS1
YPR137W	RRP9	rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	ABF1, HIR1, RCS1
YNL308C	KRI1	ribosome biogenesis -> cell organization and biogenesis		nucleolus -> nucleus
\|YMR302C\|	PRP12	mitochondrial genome maintenance, rRNA processing -> cell organization and biogenesis, RNA metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	exonuclease activity -> hydrolase activity\, acting on ester bonds	mitochondrial inner membrane -> cytoplasm, inner membrane
YGR251W	NO SYMBOL				MSN4, PHD1, SKN7
YAL059W	ECM1	cell wall organization and biogenesis -> cell organization and biogenesis			MOT3
Main:		cell organization and biogenesis (1.00)	RNA binding (0.67)	nucleus (0.75)	ABF1 (0.25)
Score:		1.00	0.67	0.67	0.000
P-value:		7.075E-04 (ribosome biogenesis)	1.507E-02 (exonuclease activity)	1.602E-01 (nucleolus)	3.331E-01 (ZMS1)

ORF	SYMBOL	P	F	C	TF
YOL041C	NOP12	rRNA metabolism -> rRNA metabolism	RNA binding -> RNA binding	nucleolus -> nucleus	GTS1, MET31
\|YGR283C\|	NO SYMBOL				ACE2, RAP1, SMP1
\|YDR312W\|	SSF2	ribosomal large subunit assembly and maintenance, conjugation with cellular fusion -> ribosome biogenesis and assembly, conjugation with cellular fusion	rRNA binding -> RNA binding	nucleolus -> nucleus	ABF1, FKH2, INO4, RAP1
YJL069C	UTP18				ABF1
YKL014C	NO SYMBOL				ABF1
YER110C	KAP123	protein-nucleus import -> intracellular protein transport, nucleocytoplasmic transport, protein metabolism	protein carrier activity -> protein carrier activity	cytoplasm, nuclear pore, nucleus -> cytoplasm, nucleus, integral to membrane, endomembrane system
YGR187C	HGH1				ABF1, HAP3, HIR1, RCS1, RTG1
YDL063C	NO SYMBOL				HAL9, HAP2, MOT3
\|YKL078W\|	DHR2	ribosome biogenesis -> ribosome biogenesis and assembly	RNA helicase activity -> RNA binding	nucleolus -> nucleus	ABF1
Main:		ribosome biogenesis and assembly (0.50)	RNA binding (0.75)	nucleus (1.00)	ABF1 (0.62)
Score:		0.17	0.50	1.00	0.393
P-value:		6.381E-01 (ribosome biogenesis and assembly)	1.473E-01 (RNA binding)	2.890E-02 (nucleolus)	2.023E-03 (ABF1)

ORF	SYMBOL	P	F	C	TF
YKL172W	EBP2	rRNA processing -> ribosome biogenesis, RNA processing, transcription from Pol I promoter		nucleolus -> nucleus	ABF1, FZF1, RFX1
YJL069C	UTP18				ABF1
YKL014C	NO SYMBOL				ABF1
YER110C	KAP123	protein-nucleus import -> protein targeting, nucleocytoplasmic transport	protein carrier activity -> protein carrier activity	cytoplasm, nuclear pore, nucleus -> cytoplasm, nucleus, integral to membrane, endomembrane system
\|YPR010C\|	RPA135	transcription from Pol I promoter -> transcription from Pol I promoter	DNA-directed RNA polymerase activity -> DNA-directed RNA polymerase activity	DNA-directed RNA polymerase I complex -> nucleus	ROX1, SIG1
YGR187C	HGH1				ABF1, HAP3, HIR1, RCS1, RTG1
YJL050W	MTR4	35S primary transcript processing -> ribosome biogenesis, RNA processing, transcription from Pol I promoter	ATP dependent RNA helicase activity -> RNA helicase activity, ATP dependent helicase activity, RNA dependent ATPase activity	nucleolus -> nucleus
YNL112W	DBP2		RNA helicase activity -> RNA helicase activity	bud neck -> site of polarized growth (sensu Fungi)
\|YNR046W\|	NO SYMBOL				ABF1
YDL063C	NO SYMBOL				HAL9, HAP2, MOT3
Main:		transcription from Pol I promoter (0.75)	RNA helicase activity (0.50)	nucleus (0.80)	ABF1 (0.71)
Score:		0.50	0.17	0.60	0.476
P-value:		8.012E-02 (transcription from Pol I promoter)	3.529E-02 (RNA helicase activity)	4.007E-02 (nucleolus)	3.060E-03 (ABF1)

ORF	SYMBOL	P	F	C	TF
\|YER115C\|	SPR6	sporulation (sensu Fungi) -> sporulation (sensu Fungi)			ARG80, RTG3
YOL022C	NO SYMBOL				MAC1, MOT3, RTS2
YCL059C	KRR1	ribosome biogenesis, rRNA processing -> ribosome biogenesis, rRNA processing		nucleolus -> nucleolus
YLR276C	DBP9	ribosomal large subunit assembly and maintenance, 35S primary transcript processing -> ribosomal subunit assembly, rRNA processing	ATP dependent RNA helicase activity -> ATP dependent RNA helicase activity	nucleolus -> nucleolus	MATa1, RCS1, RTG3, SWI5
\|YCR090C\|	NO SYMBOL
YBR104W	YMC2	transport -> transport	transporter activity -> transporter activity	mitochondrial inner membrane -> mitochondrial inner membrane	FKH1, FKH2
YNR024W	NO SYMBOL
Main:		rRNA processing (0.50)	ATP dependent RNA helicase activity (0.50)	nucleolus (0.67)	RTG3 (0.50)
Score:		0.17	0.00	0.33	0.167
P-value:		3.283E-01 (rRNA processing)	2.000E+00	1.871E-01 (nucleolus)	4.091E-02 (RTG3)

ORF	SYMBOL	P	F	C	TF
YBR159W	NO SYMBOL				ACE2, ARG81, GCR2, HIR2, LEU3, MOT3, PDR1, PHD1, SKN7, USV1
YDR317W	NO SYMBOL				HAL9, RLM1
YCR045C	NO SYMBOL
\|YKL096W\|	CWP1	cell wall organization and biogenesis -> cell wall organization and biogenesis	structural constituent of cell wall -> structural constituent of cell wall	cell wall (sensu Fungi) -> cell wall (sensu Fungi)	RLM1, SMP1, STE12, SWI4
YMR252C	NO SYMBOL				SKN7
YDR281C	PHM6				PHO4, SUM1
Main:		cell wall organization and biogenesis (1.00)	structural constituent of cell wall (1.00)	cell wall (sensu Fungi) (1.00)	RLM1 SKN7 (0.40)
Score:		0.00	0.00	0.00	0.200
P-value:		0.000E+00	0.000E+00	0.000E+00	1.236E-01 (RLM1)