CSRE(1) AND RAP1(1) => SimExpr(other) OR SimExpr(YJR145C) : 3 8
EXPR: (0.080) CSRE (P < 0.000) RAP1 (P < 0.184)
ORF | SYMBOL | P | F | C | TF |
YKL152C | GPM1 | gluconeogenesis, glycolysis -> alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism | phosphoglycerate mutase activity -> phosphoglycerate mutase activity | cytosol -> cytosol | GCR1, GCR2, HSF1, RAP1 |
|YER047C| | SAP1 | | | | MSS11 |
YDR450W | RPS18A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> cytosol, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome | FHL1, GAT3, HIR2, RAP1, RGM1, YAP5 |
|YOR213C| | SAS5 | chromatin silencing at telomere -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription | acetyltransferase activity -> acetyltransferase activity | nuclear chromosome\, telomeric region, nuclear chromatin -> chromosome\, telomeric region, chromatin, nuclear chromosome | GRF10(Pho2), SUM1 |
|YGR254W| | ENO1 | gluconeogenesis, glycolysis -> alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism | phosphopyruvate hydratase activity -> phosphopyruvate hydratase activity | phosphopyruvate hydratase complex, cytoplasm -> cytosol, cytoplasm | FKH2, MSN4, PDR1, SWI5, YAP5 |
YJR145C | RPS4A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya), cytoplasm -> cytosol, cytoplasm, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome | ACE2, CIN5, FHL1, INO4, MTH1, RAP1, YAP6 |
YGL147C | RPL9A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytosol, ribosome | FHL1, MBP1, RAP1, SWI4 |
YLR344W | RPL26A | protein biosynthesis -> biosynthesis, protein metabolism | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytosol, ribosome | FHL1, RAP1 |
YGR214W | RPS0A | protein biosynthesis, ribosomal small subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> cytosol, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome | FHL1, RAP1 |
YPL090C | RPS6A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> cytosol, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome | FHL1, GAT3, INO4, RAP1, YAP5 |
YNL069C | RPL16B | protein biosynthesis -> biosynthesis, protein metabolism | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytosol, ribosome | FHL1, GAT3, PDR1, RAP1, RGM1, YAP5 |
Main: | | biosynthesis (0.90) | structural constituent of ribosome (0.70) | cytosol (0.90) | RAP1 (0.73) |
Score: | | 0.82 | 0.47 | 0.80 | 0.564 |
P-value: | | 8.785E-03 (protein biosynthesis) | 5.221E-05 (structural constituent of ribosome) | 1.964E-05 (cytosol) | 1.131E-05 (RAP1) |
RAP1(1) AND SFF(1) AND SWI5(1) => SimExpr(YJR145C) OR SimExpr(other) : 10 4
EXPR: (0.090) SFF (P < 0.000) SWI5 (P < 0.000) RAP1 (P < 0.415)
ORF | SYMBOL | P | F | C | TF |
|YBR295W| | PCA1 | copper ion homeostasis -> cell homeostasis | P-type ATPase activity -> ATPase activity\, coupled to transmembrane movement of substances, P-P-bond-hydrolysis-driven transporter activity, cation transporter activity | membrane -> membrane | GAL4, SMP1 |
|YLR452C| | SST2 | signal transduction, adaptation to pheromone during conjugation with cellular fusion -> signal transduction, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus | GTPase activator activity -> GTPase activator activity | plasma membrane -> membrane | DIG1, FHL1, RAP1, STE12 |
YOR369C | RPS12 | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | ARG80, FHL1, FKH2, LEU3, NDD1, PDR1, RME1, SMP1, YAP6 |
|YMR224C| | MRE11 | DNA repair, double-strand break repair via nonhomologous end-joining, meiotic DNA double-strand break formation, meiotic DNA double-strand break processing, double-strand break repair via break-induced replication -> DNA metabolism, cell proliferation, catabolism | endonuclease activity, 3'-5' exonuclease activity, protein binding -> endonuclease activity, 3'-5' exonuclease activity, protein binding | nucleus -> nucleus | RAP1 |
YJR145C | RPS4A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya), cytoplasm -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | ACE2, CIN5, FHL1, INO4, MTH1, RAP1, YAP6 |
YKR092C | SRP40 | nucleocytoplasmic transport -> transport | chaperone activity -> chaperone activity | nucleolus -> nucleus | CUP9, MET4, RAP1 |
YBL087C | RPL23A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, IXR1, MSS11, PDR1, RAP1, SMP1, SOK2 |
|YDR406W| | PDR15 | transport -> transport | ATP-binding cassette (ABC) transporter activity -> ATPase activity\, coupled to transmembrane movement of substances, P-P-bond-hydrolysis-driven transporter activity | integral to membrane -> membrane | |
YKL006W | RPL14A | protein biosynthesis -> biosynthesis, protein metabolism | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, GRF10(Pho2), GTS1, RAP1 |
YLR441C | RPS1A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, GAT3, RAP1, YAP5 |
YLR344W | RPL26A | protein biosynthesis -> biosynthesis, protein metabolism | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, RAP1 |
YLR249W | YEF3 | translational elongation -> biosynthesis, protein metabolism | translation elongation factor activity -> translation elongation factor activity | ribosome -> cytoplasm, ribonucleoprotein complex | INO2, INO4 |
YER074W | RPS24A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, GAT3, PDR1, RAP1, RGM1, SMP1, YAP5 |
YNL069C | RPL16B | protein biosynthesis -> biosynthesis, protein metabolism | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, PDR1, RAP1, RGM1, YAP5 |
Main: | | biosynthesis (0.64) | structural constituent of ribosome (0.57) | cytoplasm (0.64) | RAP1 (0.77) |
Score: | | 0.41 | 0.32 | 0.44 | 0.731 |
P-value: | | 3.354E-04 (protein biosynthesis) | 9.333E-05 (structural constituent of ribosome) | 1.252E-05 (cytosolic ribosome (sensu Eukarya)) | 3.620E-07 (FHL1) |
RAP1(1) AND LYS14(1) => SimExpr(YJR145C) OR SimExpr(other) : 5 2
EXPR: (0.092) LYS14 (P < 0.002) RAP1 (P < 0.484)
ORF | SYMBOL | P | F | C | TF |
YKL152C | GPM1 | gluconeogenesis, glycolysis -> alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism | phosphoglycerate mutase activity -> phosphoglycerate mutase activity | cytosol -> cytoplasm | GCR1, GCR2, HSF1, RAP1 |
YNL302C | RPS19B | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, RAP1 |
YKL180W | RPL17A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya), cytoplasm -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, RAP1 |
|YBL093C| | ROX3 | transcription from Pol II promoter -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | RNA polymerase II transcription mediator activity -> RNA polymerase II transcription mediator activity | mediator complex, nucleus -> nucleus | FHL1, RAP1 |
YJR145C | RPS4A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya), cytoplasm -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | ACE2, CIN5, FHL1, INO4, MTH1, RAP1, YAP6 |
|YHL038C| | CBP2 | RNA splicing -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | pre-mRNA splicing factor activity -> pre-mRNA splicing factor activity | mitochondrion -> cytoplasm | RAP1 |
YBR118W | TEF2 | translational elongation -> biosynthesis, protein metabolism | translation elongation factor activity -> translation elongation factor activity | ribosome -> cytoplasm, ribonucleoprotein complex | FHL1, RAP1 |
Main: | | biosynthesis (0.71) | structural constituent of ribosome (0.43) | cytoplasm (0.86) | RAP1 (1.00) |
Score: | | 0.52 | 0.14 | 0.71 | 1.000 |
P-value: | | 1.041E-01 (protein biosynthesis) | 9.819E-02 (structural constituent of ribosome) | 4.950E-02 (ribosome) | 4.839E-07 (RAP1) |
CSRE(1) AND mRRPE(1) AND SWI5(1) => SimExpr(YOR310C) OR SimExpr(other) : 5 1
EXPR: (0.088) mRRPE (P < 0.014) SWI5 (P < 0.000) CSRE (P < 0.001)
ORF | SYMBOL | P | F | C | TF |
YOR310C | NOP58 | rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription | | small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex | ABF1, SWI6 |
YDR399W | HPT1 | purine nucleotide biosynthesis -> biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | hypoxanthine phosphoribosyltransferase activity -> hypoxanthine phosphoribosyltransferase activity | | |
YNL111C | CYB5 | sterol biosynthesis -> alcohol metabolism, biosynthesis, lipid metabolism | electron transporter activity -> electron transporter activity | microsome -> membrane fraction | ABF1, GCR2, GTS1, NRG1, REB1, ROX1 |
|YKL093W| | MBR1 | aerobic respiration -> energy pathways | | | |
YOR063W | RPL3 | protein biosynthesis, ribosomal large subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | GRF10(Pho2) |
YKL181W | PRS1 | histidine biosynthesis, tryptophan biosynthesis, purine salvage, 'de novo' IMP biosynthesis, 'de novo' pyrimidine base biosynthesis -> amine metabolism, nucleotide biosynthesis, purine ribonucleotide metabolism, aromatic compound metabolism, amino acid derivative biosynthesis, biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, amino acid and derivative metabolism, organic acid metabolism, heterocycle metabolism | ribose-phosphate pyrophosphokinase activity -> ribose-phosphate pyrophosphokinase activity | | |
Main: | | biosynthesis (0.67) | ribose-phosphate pyrophosphokinase activity (0.25) | ribonucleoprotein complex (0.67) | ABF1 (0.67) |
Score: | | 0.60 | 0.00 | 0.33 | 0.333 |
P-value: | | 7.359E-03 (purine nucleotide biosynthesis) | 8.645E-01 (transferase activity) | 9.991E-01 (ribonucleoprotein complex) | 5.694E-01 (ABF1) |
mRRPE(1) AND PAC(1) => SimExpr(YOR310C) OR SimExpr(other) : 27 2
EXPR: (0.089) mRRPE (P < 0.000) PAC (P < 0.000)
ORF | SYMBOL | P | F | C | TF |
YGR159C | NSR1 | ribosomal small subunit assembly and maintenance, rRNA processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | single-stranded DNA binding, RNA binding -> DNA binding, RNA binding | nucleolus, nucleus -> nucleus | |
|YGL016W| | KAP122 | protein-nucleus import, response to drug -> response to abiotic stimulus, protein metabolism, cell growth and/or maintenance | protein carrier activity -> transporter activity | cytoplasm, nuclear pore -> cytoplasm, nucleus, integral to membrane, endomembrane system | MSN2 |
YOR272W | YTM1 | chromosome organization and biogenesis (sensu Eukarya), ribosomal large subunit biogenesis -> cell growth and/or maintenance | | nucleus, nucleolus -> nucleus | LEU3, PUT3, REB1 |
YER110C | KAP123 | protein-nucleus import -> protein metabolism, cell growth and/or maintenance | protein carrier activity -> transporter activity | cytoplasm, nuclear pore, nucleus -> cytoplasm, nucleus, integral to membrane, endomembrane system | |
YBR104W | YMC2 | transport -> cell growth and/or maintenance | transporter activity -> transporter activity | mitochondrial inner membrane -> cytoplasm, inner membrane | FKH1, FKH2 |
YOR095C | RKI1 | pentose-phosphate shunt -> coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism | ribose-5-phosphate isomerase activity -> intramolecular isomerase activity | | FHL1, FKH2, RAP1 |
YOR310C | NOP58 | rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription | | small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex | ABF1, SWI6 |
YGL171W | ROK1 | 35S primary transcript processing, mRNA splicing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | ATP dependent RNA helicase activity, ATPase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides | nucleolus -> nucleus | RGT1 |
YJL148W | RPA34 | transcription from Pol I promoter -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | DNA-directed RNA polymerase activity -> transferase activity\, transferring phosphorus-containing groups | DNA-directed RNA polymerase I complex, nucleus, nucleolus -> nucleus | AZF1, CHA4, CUP9, DAL81, DIG1, FZF1, GCR1, GCR2, GLN3, HAL9, HAP2, HAP3, HMS1, LEU3, MAC1, MBP1, MET31, MOT3, NDD1, PDR1, PHD1, REB1, RLM1, RME1, ROX1, RPH1, RTS2, SKN7, SWI5, YAP6, ZAP1 |
YJL050W | MTR4 | 35S primary transcript processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | ATP dependent RNA helicase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides | nucleolus -> nucleus | |
YDR184C | ATC1 | response to stress, polar budding -> response to stress, asexual reproduction | | nucleus -> nucleus | ARO80, GLN3, SIP4, SKO1 |
YDR399W | HPT1 | purine nucleotide biosynthesis -> biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | hypoxanthine phosphoribosyltransferase activity -> transferase activity\, transferring glycosyl groups | | |
YBR247C | ENP1 | processing of 20S pre-rRNA, rRNA processing, cell growth and/or maintenance -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | snoRNA binding -> RNA binding | nucleolus, nucleus -> nucleus | |
YNL112W | DBP2 | | RNA helicase activity -> RNA binding | bud neck -> site of polarized growth (sensu Fungi) | |
YJL033W | HCA4 | 35S primary transcript processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | ATP dependent RNA helicase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides | nucleolus -> nucleus | HIR2, USV1 |
YHR089C | GAR1 | rRNA modification, 35S primary transcript processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription | RNA binding -> RNA binding | nucleolus, small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex | CBF1, FZF1 |
YAL059W | ECM1 | cell wall organization and biogenesis -> cell growth and/or maintenance | | | MOT3 |
YGR162W | TIF4631 | translational initiation -> biosynthesis, protein metabolism | translation initiation factor activity -> translation factor activity\, nucleic acid binding | ribosome -> cytoplasm, ribonucleoprotein complex | HSF1 |
YMR229C | RRP5 | rRNA processing, processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | RNA binding, snoRNA binding -> RNA binding | nucleolus, nucleolus organizer complex -> nucleus | FHL1, RAP1 |
YJR002W | MPP10 | rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription | | small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex, nucleolus, nucleus -> nucleus, ribonucleoprotein complex | |
YNL209W | SSB2 | protein biosynthesis -> biosynthesis, protein metabolism | chaperone activity, ATPase activity -> chaperone activity, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides | polysome, cytoplasm -> cytoplasm, ribonucleoprotein complex | ABF1, RFX1 |
YLR197W | SIK1 | rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription | | small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex, nucleus, nucleolus -> nucleus, ribonucleoprotein complex | DAL81, HAL9 |
YPL043W | NOP4 | rRNA processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | RNA binding -> RNA binding | nucleolus -> nucleus | |
YMR239C | RNT1 | 35S primary transcript processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | ribonuclease III activity -> hydrolase activity\, acting on ester bonds, RNA binding | nucleolus -> nucleus | |
YJL138C | TIF2 | translational initiation, regulation of translational initiation -> biosynthesis, protein metabolism | translation initiation factor activity, RNA helicase activity -> translation factor activity\, nucleic acid binding, RNA binding | ribosome, cytoplasm -> cytoplasm, ribonucleoprotein complex | PHD1 |
YGL078C | DBP3 | ribosomal large subunit assembly and maintenance, 35S primary transcript processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | ATP dependent RNA helicase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides | nucleolus -> nucleus | |
YNL292W | PUS4 | tRNA modification -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | pseudouridylate synthase activity -> carbon-oxygen lyase activity | mitochondrion, nucleus -> cytoplasm, nucleus | RCS1 |
YLR249W | YEF3 | translational elongation -> biosynthesis, protein metabolism | translation elongation factor activity -> translation factor activity\, nucleic acid binding | ribosome -> cytoplasm, ribonucleoprotein complex | INO2, INO4 |
|YHR128W| | FUR1 | pyrimidine salvage -> biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | uracil phosphoribosyltransferase activity -> transferase activity\, transferring glycosyl groups | | CIN5 |
Main: | | cell growth and/or maintenance (0.64) | RNA binding (0.52) | nucleus (0.76) | ABF1 GLN3 FZF1 FKH2 PHD1 REB1 LEU3 FHL1 DAL81 RAP1 MOT3 HAL9 (0.11) |
Score: | | 0.62 | 0.30 | 0.71 | 0.053 |
P-value: | | 9.273E-14 (ribosome biogenesis) | 6.040E-06 (RNA binding) | 6.059E-16 (nucleolus) | 1.000E+00 |
CSRE(1) AND PAC(1) => SimExpr(other) OR SimExpr(YOR310C) : 3 7
EXPR: (0.090) PAC (P < 0.033) CSRE (P < 0.000)
ORF | SYMBOL | P | F | C | TF |
YGR159C | NSR1 | ribosomal small subunit assembly and maintenance, rRNA processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | single-stranded DNA binding, RNA binding -> single-stranded DNA binding, RNA binding | nucleolus, nucleus -> nucleus | |
YPL143W | RPL33A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, MET4, NDD1, PDR1, RAP1, RME1 |
|YBL066C| | SEF1 | | | | |
YOR310C | NOP58 | rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription | | small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex | ABF1, SWI6 |
YBR034C | HMT1 | peptidyl-arginine modification, mRNA-nucleus export -> protein metabolism, transport, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | protein-arginine N-methyltransferase activity -> protein-arginine N-methyltransferase activity | nucleus -> nucleus | |
YDR087C | RRP1 | rRNA processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | | | |
YDR399W | HPT1 | purine nucleotide biosynthesis -> biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | hypoxanthine phosphoribosyltransferase activity -> hypoxanthine phosphoribosyltransferase activity | | |
|YER088C| | DOT6 | filamentous growth, regulation of transcription from Pol II promoter, chromatin silencing at telomere, chromatin silencing at ribosomal DNA (rDNA), cell elongation -> cell growth, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, DNA packaging, cell organization and biogenesis | | | RAP1, SKN7 |
|YML043C| | RRN11 | transcription from Pol I promoter -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | RNA polymerase I transcription factor activity -> RNA polymerase I transcription factor activity | RNA polymerase I transcription factor complex -> nucleus | MAL13 |
YHR170W | NMD3 | ribosomal large subunit assembly and maintenance -> cell organization and biogenesis | RNA binding, protein binding -> RNA binding, protein binding | cytosol, cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribosome | PHD1, REB1, SIP4 |
Main: | | nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.78) | RNA binding (0.33) | nucleus (0.67) | RAP1 (0.40) |
Score: | | 0.75 | 0.07 | 0.53 | 0.100 |
P-value: | | 3.384E-03 (transcription from Pol I promoter) | 1.145E+00 (RNA binding) | 3.786E-02 (nucleolus) | 1.000E+00 |
mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YOR310C) : 11
EXPR: (0.079) mRRPE (P < 0.000) PAC (P < 0.000) SCB (P < 0.000)
ORF | SYMBOL | P | F | C | TF |
YGR159C | NSR1 | ribosomal small subunit assembly and maintenance, rRNA processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | single-stranded DNA binding, RNA binding -> DNA binding, RNA binding | nucleolus, nucleus -> nucleus | |
YBR104W | YMC2 | transport -> transport | transporter activity -> transporter activity | mitochondrial inner membrane -> cytoplasm, inner membrane | FKH1, FKH2 |
YOR310C | NOP58 | rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription | | small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex | ABF1, SWI6 |
YDR184C | ATC1 | response to stress, polar budding -> response to stress, asexual reproduction | | nucleus -> nucleus | ARO80, GLN3, SIP4, SKO1 |
YDR399W | HPT1 | purine nucleotide biosynthesis -> biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | hypoxanthine phosphoribosyltransferase activity -> transferase activity\, transferring glycosyl groups | | |
YNL112W | DBP2 | | RNA helicase activity -> RNA binding | bud neck -> site of polarized growth (sensu Fungi) | |
YLR197W | SIK1 | rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription | | small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex, nucleus, nucleolus -> nucleus, ribonucleoprotein complex | DAL81, HAL9 |
YMR239C | RNT1 | 35S primary transcript processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | ribonuclease III activity -> hydrolase activity\, acting on ester bonds, RNA binding | nucleolus -> nucleus | |
YJL138C | TIF2 | translational initiation, regulation of translational initiation -> biosynthesis, protein metabolism | translation initiation factor activity, RNA helicase activity -> translation factor activity\, nucleic acid binding, RNA binding | ribosome, cytoplasm -> cytoplasm, ribonucleoprotein complex | PHD1 |
YNL292W | PUS4 | tRNA modification -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | pseudouridylate synthase activity -> carbon-oxygen lyase activity | mitochondrion, nucleus -> cytoplasm, nucleus | RCS1 |
YLR249W | YEF3 | translational elongation -> biosynthesis, protein metabolism | translation elongation factor activity -> translation factor activity\, nucleic acid binding | ribosome -> cytoplasm, ribonucleoprotein complex | INO2, INO4 |
Main: | | nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.60) | RNA binding (0.50) | nucleus (0.60) | ABF1 (0.14) |
Score: | | 0.40 | 0.25 | 0.56 | 0.000 |
P-value: | | 9.830E-04 (RNA modification) | 5.976E-02 (RNA binding) | 2.724E-03 (nucleolus) | 9.048E-01 (SKO1) |
ALPHA1'(1) AND SFF'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YOR310C) : 7
EXPR: (0.089) ALPHA1' (P < 0.000) SFF' (P < 0.000) mRRPE (P < 0.007) PAC (P < 0.033)
ORF | SYMBOL | P | F | C | TF |
YBR104W | YMC2 | transport -> transport | transporter activity -> transporter activity | mitochondrial inner membrane -> cytoplasm, inner membrane | FKH1, FKH2 |
YJL033W | HCA4 | 35S primary transcript processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | ATP dependent RNA helicase activity -> RNA helicase activity, ATP dependent helicase activity, RNA dependent ATPase activity | nucleolus -> nucleus | HIR2, USV1 |
YER110C | KAP123 | protein-nucleus import -> protein metabolism, transport | protein carrier activity -> transporter activity | cytoplasm, nuclear pore, nucleus -> cytoplasm, nucleus, integral to membrane, endomembrane system | |
YNL112W | DBP2 | | RNA helicase activity -> RNA helicase activity | bud neck -> site of polarized growth (sensu Fungi) | |
YNL292W | PUS4 | tRNA modification -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | pseudouridylate synthase activity -> pseudouridylate synthase activity | mitochondrion, nucleus -> cytoplasm, nucleus | RCS1 |
YOR310C | NOP58 | rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription | | small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex | ABF1, SWI6 |
YOR095C | RKI1 | pentose-phosphate shunt -> coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism | ribose-5-phosphate isomerase activity -> ribose-5-phosphate isomerase activity | | FHL1, FKH2, RAP1 |
Main: | | nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.50) | RNA helicase activity (0.33) | nucleus (0.67) | FKH2 (0.40) |
Score: | | 0.27 | 0.13 | 0.53 | 0.100 |
P-value: | | 1.821E-02 (RNA modification) | 2.382E-02 (RNA helicase activity) | 1.639E-01 (nucleolus) | 1.689E-01 (FKH2) |
CSRE(1) AND LYS14(1) AND ALPHA1'(1) => SimExpr(other) OR SimExpr(YOR063W) : 2 7
EXPR: (0.100) LYS14 (P < 0.001) ALPHA1' (P < 0.001) CSRE (P < 0.001)
ORF | SYMBOL | P | F | C | TF |
|YGL038C| | OCH1 | N-linked glycoprotein maturation -> biosynthesis, protein metabolism | transferase activity\, transferring glycosyl groups, alpha-1\,6-mannosyltransferase activity -> transferase activity\, transferring glycosyl groups | Golgi cis cisterna -> cytoplasm | CRZ1, SKN7, SWI4, SWI6 |
YLR153C | ACS2 | acetyl-CoA biosynthesis -> biosynthesis, coenzymes and prosthetic group metabolism, organic acid metabolism | acetate-CoA ligase activity -> ligase activity\, forming carbon-sulfur bonds | cytosol -> cytoplasm | |
YBR143C | SUP45 | translational termination -> biosynthesis, protein metabolism | translation release factor activity\, codon specific -> translation factor activity\, nucleic acid binding | cytosol -> cytoplasm | FZF1 |
YOL052C | SPE2 | pantothenate biosynthesis -> biosynthesis, coenzymes and prosthetic group metabolism | adenosylmethionine decarboxylase activity -> carbon-carbon lyase activity | | |
YDL048C | STP4 | | | | HIR2 |
YOR063W | RPL3 | protein biosynthesis, ribosomal large subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | GRF10(Pho2) |
YDL131W | LYS21 | lysine biosynthesis\, aminoadipic pathway -> amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis | homocitrate synthase activity -> carbon-carbon lyase activity | nucleus -> nucleus | |
|YNL241C| | ZWF1 | pentose-phosphate shunt -> coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism | glucose-6-phosphate 1-dehydrogenase activity -> oxidoreductase activity\, acting on CH-OH group of donors | cytoplasm -> cytoplasm | ACE2, ADR1, FKH2, HIR1, IME4, MBP1, NDD1, PHO4, RCS1, SFP1, SKN7, SWI5 |
YIL052C | RPL34B | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | RME1 |
Main: | | biosynthesis (0.88) | structural constituent of ribosome (0.25) | cytoplasm (0.86) | SKN7 (0.33) |
Score: | | 0.82 | 0.07 | 0.71 | 0.067 |
P-value: | | 1.004E-02 (coenzyme metabolism) | 1.446E-01 (carbon-carbon lyase activity) | 3.665E-01 (cytosol) | 6.794E-01 (SKN7) |
SWI5(1) AND PAC(1) => SimExpr(YDR399W) OR SimExpr(other) : 8 3
EXPR: (0.104) SWI5 (P < 0.000) PAC (P < 0.135)
ORF | SYMBOL | P | F | C | TF |
|YGL016W| | KAP122 | protein-nucleus import, response to drug -> response to abiotic stimulus, protein metabolism, transport | protein carrier activity -> protein carrier activity | cytoplasm, nuclear pore -> cytoplasm, nucleus, integral to membrane, endomembrane system | MSN2 |
YDR399W | HPT1 | purine nucleotide biosynthesis -> biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | hypoxanthine phosphoribosyltransferase activity -> hypoxanthine phosphoribosyltransferase activity | | |
YMR229C | RRP5 | rRNA processing, processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | RNA binding, snoRNA binding -> RNA binding, snoRNA binding | nucleolus, nucleolus organizer complex -> nucleus | FHL1, RAP1 |
YJR002W | MPP10 | rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription | | small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex, nucleolus, nucleus -> nucleus, ribonucleoprotein complex | |
YPL143W | RPL33A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, MET4, NDD1, PDR1, RAP1, RME1 |
YOR310C | NOP58 | rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription | | small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex | ABF1, SWI6 |
YKR092C | SRP40 | nucleocytoplasmic transport -> transport | chaperone activity -> chaperone activity | nucleolus -> nucleus | CUP9, MET4, RAP1 |
|YIL066C| | RNR3 | DNA replication -> cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | ribonucleoside-diphosphate reductase activity -> ribonucleoside-diphosphate reductase activity | cytoplasm -> cytoplasm | RFX1, STB1 |
|YFL011W| | HXT10 | hexose transport -> transport | glucose transporter activity, fructose transporter activity, mannose transporter activity, galactose transporter activity -> glucose transporter activity, fructose transporter activity, mannose transporter activity, galactose transporter activity | plasma membrane -> plasma membrane | GTS1, MBP1, RTG3 |
YHR089C | GAR1 | rRNA modification, 35S primary transcript processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription | RNA binding -> RNA binding | nucleolus, small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex | CBF1, FZF1 |
YLR249W | YEF3 | translational elongation -> biosynthesis, protein metabolism | translation elongation factor activity -> translation elongation factor activity | ribosome -> cytoplasm, ribonucleoprotein complex | INO2, INO4 |
Main: | | nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.55) | RNA binding (0.22) | nucleus (0.60) | RAP1 (0.33) |
Score: | | 0.42 | 0.03 | 0.60 | 0.083 |
P-value: | | 1.990E-04 (rRNA metabolism) | 1.335E+00 (RNA binding) | 1.072E-04 (nucleolus) | 3.231E-01 (MET4) |
PAC(1) AND SCB(1) => SimExpr(other) OR SimExpr(YDR399W) : 7 15
EXPR: (0.105) PAC (P < 0.056) SCB (P < 0.000)
ORF | SYMBOL | P | F | C | TF |
YGR159C | NSR1 | ribosomal small subunit assembly and maintenance, rRNA processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | single-stranded DNA binding, RNA binding -> nucleic acid binding | nucleolus, nucleus -> intracellular | |
YBR104W | YMC2 | transport -> transport | transporter activity -> transporter activity | mitochondrial inner membrane -> intracellular, inner membrane | FKH1, FKH2 |
YDR399W | HPT1 | purine nucleotide biosynthesis -> biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | hypoxanthine phosphoribosyltransferase activity -> transferase activity\, transferring glycosyl groups | | |
YLR197W | SIK1 | rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription | | small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex, nucleus, nucleolus -> intracellular | DAL81, HAL9 |
YJL138C | TIF2 | translational initiation, regulation of translational initiation -> biosynthesis, protein metabolism | translation initiation factor activity, RNA helicase activity -> nucleic acid binding | ribosome, cytoplasm -> intracellular | PHD1 |
YNL141W | AAH1 | adenine catabolism -> aromatic compound metabolism, catabolism, heterocycle metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | adenine deaminase activity -> hydrolase activity\, acting on carbon-nitrogen (but not peptide) bonds | | YFL044C |
YNL112W | DBP2 | | RNA helicase activity -> nucleic acid binding | bud neck -> site of polarized growth (sensu Fungi) | |
YER001W | MNN1 | N-glycan processing, O-linked glycosylation -> biosynthesis, protein metabolism | alpha-1\,3-mannosyltransferase activity -> transferase activity\, transferring glycosyl groups | Golgi apparatus -> intracellular | HAL9, MAC1, NRG1, PHD1, RLM1, SKN7, SMP1, SWI4, SWI6, YAP6 |
|YIL118W| | RHO3 | exocytosis, small GTPase mediated signal transduction, establishment of cell polarity (sensu Saccharomyces), actin filament organization -> signal transduction, cell organization and biogenesis, transport | Rho small monomeric GTPase activity, signal transducer activity -> purine nucleotide binding, signal transducer activity, hydrolase activity\, acting on acid anhydrides | intracellular -> intracellular | CIN5, NRG1, PHD1, SKN7, SOK2, YAP6 |
|YFR034C| | PHO4 | phosphate metabolism, cellular response to phosphate starvation -> phosphorus metabolism, response to extracellular stimulus, response to biotic stimulus | transcription factor activity -> nucleic acid binding | nucleus, cytoplasm -> intracellular | |
YNL292W | PUS4 | tRNA modification -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | pseudouridylate synthase activity -> carbon-oxygen lyase activity | mitochondrion, nucleus -> intracellular | RCS1 |
YOR310C | NOP58 | rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription | | small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex -> intracellular | ABF1, SWI6 |
YDR184C | ATC1 | response to stress, polar budding -> response to stress, asexual reproduction | | nucleus -> intracellular | ARO80, GLN3, SIP4, SKO1 |
|YBL099W| | ATP1 | ATP synthesis coupled proton transport -> transport | hydrogen-transporting ATP synthase activity -> transporter activity | proton-transporting ATP synthase\, catalytic core (sensu Eukarya) -> intracellular, integral to membrane, inner membrane | HAP4, ROX1 |
|YDR364C| | CDC40 | DNA replication, S phase of mitotic cell cycle, mRNA splicing, mitotic spindle assembly (sensu Saccharomyces) -> cytoplasm organization and biogenesis, cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, M phase | nucleic acid binding, pre-mRNA splicing factor activity -> nucleic acid binding | spliceosome complex, nuclear membrane, nuclear pore -> pore complex, intracellular, endomembrane system | |
YJL208C | NUC1 | DNA recombination -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | endodeoxyribonuclease activity, exodeoxyribonuclease activity, ribonuclease activity -> hydrolase activity\, acting on ester bonds, nucleic acid binding | mitochondrial inner membrane -> intracellular, inner membrane | |
|YIL066C| | RNR3 | DNA replication -> cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | ribonucleoside-diphosphate reductase activity -> oxidoreductase activity\, acting on CH2 groups | cytoplasm -> intracellular | RFX1, STB1 |
YBR034C | HMT1 | peptidyl-arginine modification, mRNA-nucleus export -> protein metabolism, transport, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | protein-arginine N-methyltransferase activity -> transferase activity\, transferring one-carbon groups | nucleus -> intracellular | |
|YDR076W| | RAD55 | meiotic DNA recombinase assembly, DNA recombinase assembly, double-strand break repair via synthesis-dependent strand annealing, double-strand break repair via break-induced replication, double-strand break repair via single-strand annealing -> mating-type determination, cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | protein binding -> protein binding | nucleus -> intracellular | DAL81 |
YMR239C | RNT1 | 35S primary transcript processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | ribonuclease III activity -> hydrolase activity\, acting on ester bonds, nucleic acid binding | nucleolus -> intracellular | |
|YML043C| | RRN11 | transcription from Pol I promoter -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | RNA polymerase I transcription factor activity -> RNA polymerase I transcription factor activity | RNA polymerase I transcription factor complex -> intracellular | MAL13 |
YLR249W | YEF3 | translational elongation -> biosynthesis, protein metabolism | translation elongation factor activity -> nucleic acid binding | ribosome -> intracellular | INO2, INO4 |
Main: | | nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.62) | nucleic acid binding (0.42) | intracellular (0.95) | PHD1 (0.21) |
Score: | | 0.46 | 0.18 | 0.90 | 0.066 |
P-value: | | 1.462E-02 (RNA modification) | 7.448E-02 (RNA binding) | 6.764E-03 (nucleolus) | 5.851E-01 (HAL9) |
CSRE(1) AND PAC(1) => SimExpr(other) OR SimExpr(YDR399W) : 3 7
mRRPE(1) AND PAC(1) => SimExpr(YDR399W) OR SimExpr(other) : 27 2
mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YDR399W) : 11
CSRE(1) AND PAC(1) => SimExpr(other) OR SimExpr(YBR034C) : 3 7
CSRE(1) AND PAC(1) => SimExpr(other) OR SimExpr(YPL143W) : 3 7
mRRPE(1) AND PAC(1) => SimExpr(YGR159C) OR SimExpr(other) : 28 1
CSRE(1) AND PAC(1) => SimExpr(YGR159C) OR SimExpr(other) : 8 2
CSRE(1) AND PAC(1) AND SCB(1) => SimExpr(YGR159C) : 5
EXPR: (0.070) PAC (P < 0.006) SCB (P < 0.000) CSRE (P < 0.000)
ORF | SYMBOL | P | F | C | TF |
YGR159C | NSR1 | ribosomal small subunit assembly and maintenance, rRNA processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | single-stranded DNA binding, RNA binding -> single-stranded DNA binding, RNA binding | nucleolus, nucleus -> nucleus | |
YDR399W | HPT1 | purine nucleotide biosynthesis -> biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | hypoxanthine phosphoribosyltransferase activity -> hypoxanthine phosphoribosyltransferase activity | | |
YOR310C | NOP58 | rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription | | small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex | ABF1, SWI6 |
YBR034C | HMT1 | peptidyl-arginine modification, mRNA-nucleus export -> protein metabolism, transport, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | protein-arginine N-methyltransferase activity -> protein-arginine N-methyltransferase activity | nucleus -> nucleus | |
YML043C | RRN11 | transcription from Pol I promoter -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | RNA polymerase I transcription factor activity -> RNA polymerase I transcription factor activity | RNA polymerase I transcription factor complex -> nucleus | MAL13 |
Main: | | nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (1.00) | RNA binding (0.25) | nucleus (1.00) | ABF1 (0.50) |
Score: | | 1.00 | 0.00 | 1.00 | 0.000 |
P-value: | | 4.879E-03 (transcription from Pol I promoter) | 6.354E-01 (transferase activity) | 1.622E-03 (nucleolus) | 1.397E-01 (MAL13) |
mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YGR159C) : 11
mRRPE(1) AND PAC(1) AND MCM1'(1) => SimExpr(YGR159C) : 6
EXPR: (0.074) mRRPE (P < 0.000) PAC (P < 0.011) MCM1' (P < 0.000)
ORF | SYMBOL | P | F | C | TF |
YGR159C | NSR1 | ribosomal small subunit assembly and maintenance, rRNA processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | single-stranded DNA binding, RNA binding -> single-stranded DNA binding, RNA binding | nucleolus, nucleus -> nucleolus, nucleus | |
YDR399W | HPT1 | purine nucleotide biosynthesis -> biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | hypoxanthine phosphoribosyltransferase activity -> transferase activity\, transferring pentosyl groups | | |
YHR128W | FUR1 | pyrimidine salvage -> biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | uracil phosphoribosyltransferase activity -> transferase activity\, transferring pentosyl groups | | CIN5 |
YPL043W | NOP4 | rRNA processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | RNA binding -> RNA binding | nucleolus -> nucleolus | |
YOR310C | NOP58 | rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription | | small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex -> small nuclear ribonucleoprotein complex, nucleolus, ribonucleoprotein complex | ABF1, SWI6 |
YOR095C | RKI1 | pentose-phosphate shunt -> coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism | ribose-5-phosphate isomerase activity -> intramolecular isomerase activity\, interconverting aldoses and ketoses | | FHL1, FKH2, RAP1 |
Main: | | nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.83) | transferase activity\, transferring pentosyl groups (0.40) | nucleolus (1.00) | ABF1 (0.33) |
Score: | | 0.67 | 0.20 | 1.00 | 0.000 |
P-value: | | 6.463E-03 (rRNA processing) | 9.418E-03 (transferase activity\, transferring pentosyl groups) | 3.174E-03 (nucleolus) | 1.000E+00 |
CSRE(1) AND LYS14(1) AND ALPHA1'(1) => SimExpr(other) OR SimExpr(YIL052C) : 2 7
SFF'(1) AND SWI5(1) AND MCB(1) => SimExpr(YDR309C) OR SimExpr(other) : 6 2
EXPR: (0.109) SFF' (P < 0.000) SWI5 (P < 0.000) MCB (P < 0.024)
ORF | SYMBOL | P | F | C | TF |
YOL006C | TOP1 | negative regulation of recombination within rDNA repeats, DNA topological change, DNA strand elongation, chromatin assembly/disassembly, regulation of transcription from Pol II promoter, RNA elongation from Pol II promoter, mitotic chromosome condensation, nuclear migration -> cell organization and biogenesis, cell cycle, mitotic cell cycle, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | DNA topoisomerase type I activity -> DNA topoisomerase type I activity | nucleus -> nucleus | REB1 |
YDR297W | SUR2 | sphingolipid metabolism, sphingolipid biosynthesis -> lipid metabolism, biosynthesis | sphingosine hydroxylase activity -> sphingosine hydroxylase activity | endoplasmic reticulum -> cytoplasm | CBF1, MTH1 |
YDR309C | GIC2 | axial budding, Rho protein signal transduction, establishment of cell polarity (sensu Saccharomyces) -> asexual reproduction, signal transduction, cell organization and biogenesis | small GTPase regulatory/interacting protein activity -> small GTPase regulatory/interacting protein activity | actin cap (sensu Saccharomyces), bud tip, shmoo tip, incipient bud site -> cell cortex, site of polarized growth (sensu Fungi), incipient bud site, cytoplasm | ASH1, HSF1, MBP1, PHD1, RLM1, SKN7, STB1, STE12, SWI4, SWI6 |
|YKL042W| | SPC42 | microtubule nucleation, spindle pole body duplication (sensu Saccharomyces) -> cell organization and biogenesis, cell proliferation | structural constituent of cytoskeleton -> structural constituent of cytoskeleton | intermediate layer of spindle pole body, central plaque of spindle pole body -> cytoplasm | |
YIL066C | RNR3 | DNA replication -> cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | ribonucleoside-diphosphate reductase activity -> ribonucleoside-diphosphate reductase activity | cytoplasm -> cytoplasm | RFX1, STB1 |
YMR179W | SPT21 | regulation of transcription from Pol II promoter -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | | | MBP1, STB1, SWI4, SWI6, UGA3 |
YER070W | RNR1 | DNA replication -> cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | ribonucleoside-diphosphate reductase activity -> ribonucleoside-diphosphate reductase activity | cytoplasm -> cytoplasm | FKH2, MBP1, REB1, SWI4, SWI6 |
|YDR052C| | DBF4 | DNA replication initiation, regulation of DNA replication, protein amino acid phosphorylation -> phosphorus metabolism, cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism | protein serine/threonine kinase activity -> protein serine/threonine kinase activity | nucleoplasm -> nucleus | IME4, NRG1 |
Main: | | nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.62) | ribonucleoside-diphosphate reductase activity (0.29) | cytoplasm (0.71) | SWI4 MBP1 SWI6 STB1 (0.43) |
Score: | | 0.57 | 0.05 | 0.52 | 0.286 |
P-value: | | 5.078E-04 (DNA replication and chromosome cycle) | 1.156E-03 (oxidoreductase activity\, acting on CH2 groups\, disulfide as acceptor) | 3.629E-01 (cytoskeleton) | 2.080E-03 (STB1) |
Gcr1(1) AND ATRepeat(1) => SimExpr(other) OR SimExpr(YKL152C) : 2 5
EXPR: (0.114) Gcr1 (P < 0.232) ATRepeat (P < 0.013)
ORF | SYMBOL | P | F | C | TF |
YGL038C | OCH1 | N-linked glycoprotein maturation -> biosynthesis, protein metabolism | transferase activity\, transferring glycosyl groups, alpha-1\,6-mannosyltransferase activity -> transferase activity\, transferring glycosyl groups, alpha-1\,6-mannosyltransferase activity | Golgi cis cisterna -> cytoplasm | CRZ1, SKN7, SWI4, SWI6 |
|YCL027W| | FUS1 | conjugation with cellular fusion -> conjugation, sexual reproduction | | plasma membrane, shmoo tip -> plasma membrane, site of polarized growth (sensu Fungi) | DIG1, STE12 |
YKL152C | GPM1 | gluconeogenesis, glycolysis -> alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism | phosphoglycerate mutase activity -> phosphoglycerate mutase activity | cytosol -> cytoplasm | GCR1, GCR2, HSF1, RAP1 |
YKR097W | PCK1 | gluconeogenesis -> alcohol metabolism, carbohydrate metabolism, biosynthesis, energy pathways | phosphoenolpyruvate carboxykinase (ATP) activity -> phosphoenolpyruvate carboxykinase (ATP) activity | cytosol -> cytoplasm | MCM1, MTH1, SIP4, SKN7 |
YLR354C | TAL1 | pentose-phosphate shunt -> coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism | transaldolase activity -> transaldolase activity | cytoplasm -> cytoplasm | MBP1 |
YLR121C | YPS3 | protein metabolism -> protein metabolism | aspartic-type endopeptidase activity -> aspartic-type endopeptidase activity | plasma membrane -> plasma membrane | CIN5, SWI4, YAP6 |
|YDR263C| | DIN7 | DNA repair -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | nuclease activity -> nuclease activity | mitochondrion -> cytoplasm | FKH1, FKH2, MBP1, SWI6 |
Main: | | alcohol metabolism (0.43) | transaldolase activity (0.17) | cytoplasm (0.71) | SWI4 MBP1 SWI6 SKN7 (0.29) |
Score: | | 0.29 | 0.00 | 0.52 | 0.190 |
P-value: | | 1.851E-02 (glucose metabolism) | 4.167E-01 (enzyme activity) | 7.473E-01 (plasma membrane) | 3.556E-01 (MBP1) |
LYS14(1) AND ATRepeat(1) => SimExpr(YKL152C) OR SimExpr(other) : 5 1
EXPR: (0.098) LYS14 (P < 0.001) ATRepeat (P < 0.001)
ORF | SYMBOL | P | F | C | TF |
YGL038C | OCH1 | N-linked glycoprotein maturation -> biosynthesis, protein metabolism | transferase activity\, transferring glycosyl groups, alpha-1\,6-mannosyltransferase activity -> transferase activity\, transferring glycosyl groups, alpha-1\,6-mannosyltransferase activity | Golgi cis cisterna -> cytoplasm | CRZ1, SKN7, SWI4, SWI6 |
YLR153C | ACS2 | acetyl-CoA biosynthesis -> biosynthesis, coenzymes and prosthetic group metabolism, organic acid metabolism | acetate-CoA ligase activity -> acetate-CoA ligase activity | cytosol -> cytoplasm | |
YDR226W | ADK1 | cell proliferation -> cell proliferation | adenylate kinase activity -> adenylate kinase activity | cytoplasm, mitochondrial intermembrane space -> cytoplasm | PUT3 |
YKL152C | GPM1 | gluconeogenesis, glycolysis -> alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism | phosphoglycerate mutase activity -> phosphoglycerate mutase activity | cytosol -> cytoplasm | GCR1, GCR2, HSF1, RAP1 |
YDL048C | STP4 | | | | HIR2 |
|YBR115C| | LYS2 | lysine biosynthesis\, aminoadipic pathway -> amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis | aminoadipate-semialdehyde dehydrogenase activity -> aminoadipate-semialdehyde dehydrogenase activity | cytoplasm -> cytoplasm | DAL81, GCN4 |
Main: | | biosynthesis (0.80) | adenylate kinase activity (0.20) | cytoplasm (1.00) | GCR2 (0.20) |
Score: | | 0.60 | 0.00 | 1.00 | 0.000 |
P-value: | | 3.970E-01 (biosynthesis) | 5.543E-01 (enzyme activity) | 1.341E+00 (cytosol) | 6.676E-01 (CRZ1) |
CSRE(1) AND RAP1(1) => SimExpr(YKL152C) OR SimExpr(other) : 8 3
CSRE(1) AND RAP1(1) AND SFF(1) => SimExpr(YKL152C) : 6
EXPR: (0.075) SFF (P < 0.000) CSRE (P < 0.000) RAP1 (P < 0.005)
ORF | SYMBOL | P | F | C | TF |
YGR214W | RPS0A | protein biosynthesis, ribosomal small subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> cytosol, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome | FHL1, RAP1 |
YJR145C | RPS4A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya), cytoplasm -> cytosol, cytoplasm, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome | ACE2, CIN5, FHL1, INO4, MTH1, RAP1, YAP6 |
YLR344W | RPL26A | protein biosynthesis -> biosynthesis, protein metabolism | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytosol, ribosome | FHL1, RAP1 |
YKL152C | GPM1 | gluconeogenesis, glycolysis -> alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism | phosphoglycerate mutase activity -> phosphoglycerate mutase activity | cytosol -> cytosol | GCR1, GCR2, HSF1, RAP1 |
YGR254W | ENO1 | gluconeogenesis, glycolysis -> alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism | phosphopyruvate hydratase activity -> phosphopyruvate hydratase activity | phosphopyruvate hydratase complex, cytoplasm -> cytosol, cytoplasm | FKH2, MSN4, PDR1, SWI5, YAP5 |
YNL069C | RPL16B | protein biosynthesis -> biosynthesis, protein metabolism | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytosol, ribosome | FHL1, GAT3, PDR1, RAP1, RGM1, YAP5 |
Main: | | biosynthesis (1.00) | structural constituent of ribosome (0.67) | cytosol (1.00) | RAP1 (0.83) |
Score: | | 1.00 | 0.40 | 1.00 | 0.733 |
P-value: | | 1.366E-02 (biosynthesis) | 5.227E-03 (structural constituent of ribosome) | 1.572E-04 (cytosol) | 5.499E-04 (RAP1) |
CSRE(1) AND RAP1(1) AND SFF'(1) => SimExpr(YKL152C) : 7
EXPR: (0.078) SFF' (P < 0.000) CSRE (P < 0.000) RAP1 (P < 0.006)
ORF | SYMBOL | P | F | C | TF |
YGL147C | RPL9A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytosol, ribosome | FHL1, MBP1, RAP1, SWI4 |
YGR214W | RPS0A | protein biosynthesis, ribosomal small subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> cytosol, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome | FHL1, RAP1 |
YJR145C | RPS4A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya), cytoplasm -> cytosol, cytoplasm, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome | ACE2, CIN5, FHL1, INO4, MTH1, RAP1, YAP6 |
YLR344W | RPL26A | protein biosynthesis -> biosynthesis, protein metabolism | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytosol, ribosome | FHL1, RAP1 |
YKL152C | GPM1 | gluconeogenesis, glycolysis -> alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism | phosphoglycerate mutase activity -> phosphoglycerate mutase activity | cytosol -> cytosol | GCR1, GCR2, HSF1, RAP1 |
YGR254W | ENO1 | gluconeogenesis, glycolysis -> alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism | phosphopyruvate hydratase activity -> phosphopyruvate hydratase activity | phosphopyruvate hydratase complex, cytoplasm -> cytosol, cytoplasm | FKH2, MSN4, PDR1, SWI5, YAP5 |
YNL069C | RPL16B | protein biosynthesis -> biosynthesis, protein metabolism | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytosol, ribosome | FHL1, GAT3, PDR1, RAP1, RGM1, YAP5 |
Main: | | biosynthesis (1.00) | structural constituent of ribosome (0.71) | cytosol (1.00) | RAP1 (0.86) |
Score: | | 1.00 | 0.48 | 1.00 | 0.762 |
P-value: | | 3.801E-03 (biosynthesis) | 5.957E-04 (structural constituent of ribosome) | 2.278E-05 (cytosol) | 6.256E-05 (RAP1) |
CSRE(1) AND RAP1(1) => SimExpr(other) OR SimExpr(YNL069C) : 2 9
CSRE(1) AND RAP1(1) AND SWI5(1) => SimExpr(YNL069C) : 5
EXPR: (0.065) SWI5 (P < 0.000) CSRE (P < 0.002) RAP1 (P < 0.143)
ORF | SYMBOL | P | F | C | TF |
YDR450W | RPS18A | protein biosynthesis -> protein biosynthesis | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> cytosolic ribosome (sensu Eukarya), eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, small ribosomal subunit | FHL1, GAT3, HIR2, RAP1, RGM1, YAP5 |
YJR145C | RPS4A | protein biosynthesis -> protein biosynthesis | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya), cytoplasm -> cytosolic ribosome (sensu Eukarya), cytoplasm, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, small ribosomal subunit | ACE2, CIN5, FHL1, INO4, MTH1, RAP1, YAP6 |
YLR344W | RPL26A | protein biosynthesis -> protein biosynthesis | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytosolic ribosome (sensu Eukarya), large ribosomal subunit | FHL1, RAP1 |
YOR213C | SAS5 | chromatin silencing at telomere -> chromatin silencing at telomere | acetyltransferase activity -> acetyltransferase activity | nuclear chromosome\, telomeric region, nuclear chromatin -> nuclear chromosome\, telomeric region, nuclear chromatin | GRF10(Pho2), SUM1 |
YNL069C | RPL16B | protein biosynthesis -> protein biosynthesis | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytosolic ribosome (sensu Eukarya), large ribosomal subunit | FHL1, GAT3, PDR1, RAP1, RGM1, YAP5 |
Main: | | protein biosynthesis (0.80) | structural constituent of ribosome (0.80) | cytosolic ribosome (sensu Eukarya) (0.80) | FHL1 RAP1 (0.80) |
Score: | | 0.60 | 0.60 | 0.60 | 0.600 |
P-value: | | 1.692E-02 (protein biosynthesis) | 1.631E-03 (structural constituent of ribosome) | 1.479E-03 (cytosolic ribosome (sensu Eukarya)) | 9.113E-04 (FHL1) |
RAP1(1) => SimExpr(other) OR SimExpr(YLR344W) : 15 36
EXPR: (0.103) RAP1 (P < 0.584)
ORF | SYMBOL | P | F | C | TF |
|YMR013C| | SEC59 | protein-ER targeting, protein amino acid glycosylation -> cell organization and biogenesis, biosynthesis, protein modification, protein metabolism, transport | dolichol kinase activity -> transferase activity\, transferring phosphorus-containing groups | membrane -> membrane | FHL1, NDD1, RAP1, RLM1, RME1 |
YOL121C | RPS19A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | AZF1, FHL1, GCR1, GCR2, HAL9, MET31, MOT3, PDR1, RAP1, ROX1, RPH1, SMP1, YAP6, ZAP1 |
|YLR452C| | SST2 | signal transduction, adaptation to pheromone during conjugation with cellular fusion -> signal transduction, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus | GTPase activator activity -> small GTPase regulatory/interacting protein activity | plasma membrane -> membrane | DIG1, FHL1, RAP1, STE12 |
|YLR208W| | SEC13 | nonselective vesicle assembly, ER to Golgi transport, ER-associated protein catabolism -> macromolecule catabolism, transport, protein metabolism | | cytoplasm, COPII vesicle coat, nuclear pore, extrinsic to plasma membrane -> nucleus, cytoplasm, membrane coat, membrane | |
|YEL056W| | HAT2 | chromatin assembly/disassembly, chromatin silencing at telomere -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription | H3/H4 histone acetyltransferase activity -> transferase activity\, transferring acyl groups | cytoplasm, nucleus -> cytoplasm, nucleus | GAL4 |
|YBL022C| | PIM1 | proteolysis and peptidolysis, response to heat -> catabolism, response to abiotic stimulus, protein metabolism | ATP-dependent peptidase activity -> peptidase activity | mitochondrial matrix -> cytoplasm | RAP1 |
|YBR117C| | TKL2 | pentose-phosphate shunt -> coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism | transketolase activity -> transferase activity\, transferring aldehyde or ketonic groups | | FHL1, RAP1 |
YKR057W | RPS21A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | ABF1, FHL1 |
|YHL038C| | CBP2 | RNA splicing -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | pre-mRNA splicing factor activity -> RNA binding | mitochondrion -> cytoplasm | RAP1 |
YDL130W | RPP1B | protein biosynthesis, translational elongation -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, GAL4, RAP1, RFX1 |
YKL006W | RPL14A | protein biosynthesis -> biosynthesis, protein metabolism | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, GRF10(Pho2), GTS1, RAP1 |
YGL147C | RPL9A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, MBP1, RAP1, SWI4 |
YLR441C | RPS1A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, GAT3, RAP1, YAP5 |
YLR146C | SPE4 | pantothenate biosynthesis, spermine biosynthesis -> biosynthesis, amine metabolism, coenzymes and prosthetic group metabolism, amino acid and derivative metabolism, secondary metabolism | spermine synthase activity -> transferase activity\, transferring alkyl or aryl (other than methyl) groups | | |
YBR181C | RPS6B | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya), cytoplasm -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, GAT3, MAL13, RAP1, RGM1 |
YGR214W | RPS0A | protein biosynthesis, ribosomal small subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, RAP1 |
YJR123W | RPS5 | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, GRF10(Pho2), HSF1, MSN4, YAP1 |
YDL136W | RPL35B | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, INO4, MSS11, RAP1 |
YDR450W | RPS18A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, GAT3, HIR2, RAP1, RGM1, YAP5 |
YOR369C | RPS12 | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | ARG80, FHL1, FKH2, LEU3, NDD1, PDR1, RME1, SMP1, YAP6 |
YPL131W | RPL5 | protein biosynthesis, ribosomal large subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, RAP1 |
YJR145C | RPS4A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya), cytoplasm -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | ACE2, CIN5, FHL1, INO4, MTH1, RAP1, YAP6 |
YBL087C | RPL23A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, IXR1, MSS11, PDR1, RAP1, SMP1, SOK2 |
|YDR406W| | PDR15 | transport -> transport | ATP-binding cassette (ABC) transporter activity -> purine nucleotide binding, primary active transporter activity, hydrolase activity\, acting on acid anhydrides | integral to membrane -> membrane | |
YBR118W | TEF2 | translational elongation -> biosynthesis, protein metabolism | translation elongation factor activity -> translation factor activity\, nucleic acid binding | ribosome -> cytoplasm, ribonucleoprotein complex | FHL1, RAP1 |
YLR061W | RPL22A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | BAS1, FHL1, HIR1, PDR1, RAP1, RCS1, RME1, ZAP1 |
YDR418W | RPL12B | protein biosynthesis, ribosomal large subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, PDR1, RAP1, SMP1 |
YLR344W | RPL26A | protein biosynthesis -> biosynthesis, protein metabolism | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, RAP1 |
YKL152C | GPM1 | gluconeogenesis, glycolysis -> alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism | phosphoglycerate mutase activity -> intramolecular transferase activity | cytosol -> cytoplasm | GCR1, GCR2, HSF1, RAP1 |
YNL302C | RPS19B | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, RAP1 |
|YMR231W| | PEP5 | nonselective vesicle docking, homotypic vacuole fusion (non-autophagic), Golgi to endosome transport, late endosome to vacuole transport -> cell organization and biogenesis, transport, vesicle-mediated transport | | vacuolar membrane (sensu Fungi) -> cytoplasm, vacuole | ARG81, DOT6, HAL9, HAP2, MCM1, YAP1 |
YGL030W | RPL30 | protein biosynthesis, rRNA processing, mRNA splicing, regulation of translation -> cell organization and biogenesis, biosynthesis, transcription, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya), cytoplasm -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, RAP1, SFP1 |
|YER047C| | SAP1 | | | | MSS11 |
YIL018W | RPL2B | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, PDR1, RAP1, RGM1, SWI5, YAP5 |
|YGR254W| | ENO1 | gluconeogenesis, glycolysis -> alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism | phosphopyruvate hydratase activity -> carbon-oxygen lyase activity | phosphopyruvate hydratase complex, cytoplasm -> cytoplasm | FKH2, MSN4, PDR1, SWI5, YAP5 |
YKR092C | SRP40 | nucleocytoplasmic transport -> transport | chaperone activity -> chaperone activity | nucleolus -> nucleus | CUP9, MET4, RAP1 |
YGL076C | RPL7A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | |
YER074W | RPS24A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, GAT3, PDR1, RAP1, RGM1, SMP1, YAP5 |
YBR048W | RPS11B | protein biosynthesis, ribosomal small subunit assembly and maintenance, regulation of translational fidelity -> cell organization and biogenesis, biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | GAL4, HAP4, LEU3, MET31, MSN1 |
YJR139C | HOM6 | homoserine biosynthesis, methionine metabolism, threonine metabolism -> amine metabolism, sulfur metabolism, biosynthesis, amino acid and derivative metabolism, organic acid metabolism | homoserine dehydrogenase activity -> oxidoreductase activity\, acting on CH-OH group of donors | | HMS1, RAP1 |
|YBR295W| | PCA1 | copper ion homeostasis -> cell homeostasis | P-type ATPase activity -> purine nucleotide binding, primary active transporter activity, cation transporter activity, hydrolase activity\, acting on acid anhydrides | membrane -> membrane | GAL4, SMP1 |
YKL180W | RPL17A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya), cytoplasm -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, RAP1 |
|YBL093C| | ROX3 | transcription from Pol II promoter -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | RNA polymerase II transcription mediator activity -> general RNA polymerase II transcription factor activity | mediator complex, nucleus -> nucleus | FHL1, RAP1 |
YGR085C | RPL11B | protein biosynthesis, ribosomal large subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, MIG1 |
YOR213C | SAS5 | chromatin silencing at telomere -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription | acetyltransferase activity -> transferase activity\, transferring acyl groups | nuclear chromosome\, telomeric region, nuclear chromatin -> chromosome, nuclear chromosome | GRF10(Pho2), SUM1 |
|YMR224C| | MRE11 | DNA repair, double-strand break repair via nonhomologous end-joining, meiotic DNA double-strand break formation, meiotic DNA double-strand break processing, double-strand break repair via break-induced replication -> DNA metabolism, cell proliferation, catabolism | endonuclease activity, 3'-5' exonuclease activity, protein binding -> hydrolase activity\, acting on ester bonds, protein binding | nucleus -> nucleus | RAP1 |
|YMR193W| | MRPL24 | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | mitochondrial large ribosomal subunit -> cytoplasm, ribonucleoprotein complex | ARO80, HAP4, HAP5, LEU3, MET31, RTG1, RTG3, STE12, STP1, UGA3 |
YHL033C | RPL8A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1 |
YLR249W | YEF3 | translational elongation -> biosynthesis, protein metabolism | translation elongation factor activity -> translation factor activity\, nucleic acid binding | ribosome -> cytoplasm, ribonucleoprotein complex | INO2, INO4 |
YPL090C | RPS6A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, GAT3, INO4, RAP1, YAP5 |
YNL069C | RPL16B | protein biosynthesis -> biosynthesis, protein metabolism | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, PDR1, RAP1, RGM1, YAP5 |
Main: | | biosynthesis (0.74) | structural constituent of ribosome (0.62) | cytoplasm (0.83) | RAP1 (0.70) |
Score: | | 0.64 | 0.39 | 0.70 | 0.659 |
P-value: | | 5.960E-15 (protein biosynthesis) | 4.524E-20 (structural constituent of ribosome) | 3.720E-22 (cytosolic ribosome (sensu Eukarya)) | 1.617E-27 (FHL1) |
RAP1(1) AND ALPHA1'(1) => SimExpr(other) OR SimExpr(YLR344W) : 9 20
EXPR: (0.105) ALPHA1' (P < 0.000) RAP1 (P < 0.639)
ORF | SYMBOL | P | F | C | TF |
|YMR013C| | SEC59 | protein-ER targeting, protein amino acid glycosylation -> cell organization and biogenesis, biosynthesis, protein modification, protein metabolism, transport | dolichol kinase activity -> transferase activity\, transferring phosphorus-containing groups | membrane -> membrane | FHL1, NDD1, RAP1, RLM1, RME1 |
YOL121C | RPS19A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | AZF1, FHL1, GCR1, GCR2, HAL9, MET31, MOT3, PDR1, RAP1, ROX1, RPH1, SMP1, YAP6, ZAP1 |
|YEL056W| | HAT2 | chromatin assembly/disassembly, chromatin silencing at telomere -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription | H3/H4 histone acetyltransferase activity -> transferase activity\, transferring acyl groups | cytoplasm, nucleus -> cytoplasm, nucleus | GAL4 |
|YBL022C| | PIM1 | proteolysis and peptidolysis, response to heat -> catabolism, response to abiotic stimulus, protein metabolism | ATP-dependent peptidase activity -> peptidase activity | mitochondrial matrix -> cytoplasm | RAP1 |
|YBR117C| | TKL2 | pentose-phosphate shunt -> coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism | transketolase activity -> transferase activity\, transferring aldehyde or ketonic groups | | FHL1, RAP1 |
|YHL038C| | CBP2 | RNA splicing -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | pre-mRNA splicing factor activity -> RNA binding | mitochondrion -> cytoplasm | RAP1 |
YDL130W | RPP1B | protein biosynthesis, translational elongation -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, GAL4, RAP1, RFX1 |
YLR146C | SPE4 | pantothenate biosynthesis, spermine biosynthesis -> biosynthesis, amine metabolism, coenzymes and prosthetic group metabolism, amino acid and derivative metabolism, secondary metabolism | spermine synthase activity -> transferase activity\, transferring alkyl or aryl (other than methyl) groups | | |
YBR181C | RPS6B | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya), cytoplasm -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, GAT3, MAL13, RAP1, RGM1 |
YGR214W | RPS0A | protein biosynthesis, ribosomal small subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, RAP1 |
YJR123W | RPS5 | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, GRF10(Pho2), HSF1, MSN4, YAP1 |
YDL136W | RPL35B | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, INO4, MSS11, RAP1 |
YOR369C | RPS12 | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | ARG80, FHL1, FKH2, LEU3, NDD1, PDR1, RME1, SMP1, YAP6 |
YPL131W | RPL5 | protein biosynthesis, ribosomal large subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, RAP1 |
YBR118W | TEF2 | translational elongation -> biosynthesis, protein metabolism | translation elongation factor activity -> translation factor activity\, nucleic acid binding | ribosome -> cytoplasm, ribonucleoprotein complex | FHL1, RAP1 |
YLR061W | RPL22A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | BAS1, FHL1, HIR1, PDR1, RAP1, RCS1, RME1, ZAP1 |
YDR418W | RPL12B | protein biosynthesis, ribosomal large subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, PDR1, RAP1, SMP1 |
YLR344W | RPL26A | protein biosynthesis -> biosynthesis, protein metabolism | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, RAP1 |
|YMR231W| | PEP5 | nonselective vesicle docking, homotypic vacuole fusion (non-autophagic), Golgi to endosome transport, late endosome to vacuole transport -> cell organization and biogenesis, transport, vesicle-mediated transport | | vacuolar membrane (sensu Fungi) -> cytoplasm, vacuole | ARG81, DOT6, HAL9, HAP2, MCM1, YAP1 |
|YER047C| | SAP1 | | | | MSS11 |
|YGR254W| | ENO1 | gluconeogenesis, glycolysis -> alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism | phosphopyruvate hydratase activity -> carbon-oxygen lyase activity | phosphopyruvate hydratase complex, cytoplasm -> cytoplasm | FKH2, MSN4, PDR1, SWI5, YAP5 |
YGL076C | RPL7A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | |
YER074W | RPS24A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, GAT3, PDR1, RAP1, RGM1, SMP1, YAP5 |
YBR048W | RPS11B | protein biosynthesis, ribosomal small subunit assembly and maintenance, regulation of translational fidelity -> cell organization and biogenesis, biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | GAL4, HAP4, LEU3, MET31, MSN1 |
|YBR295W| | PCA1 | copper ion homeostasis -> cell homeostasis | P-type ATPase activity -> purine nucleotide binding, primary active transporter activity, cation transporter activity, hydrolase activity\, acting on acid anhydrides | membrane -> membrane | GAL4, SMP1 |
YKL180W | RPL17A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya), cytoplasm -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, RAP1 |
YOR213C | SAS5 | chromatin silencing at telomere -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription | acetyltransferase activity -> transferase activity\, transferring acyl groups | nuclear chromosome\, telomeric region, nuclear chromatin -> chromosome, nuclear chromosome | GRF10(Pho2), SUM1 |
YHL033C | RPL8A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1 |
YPL090C | RPS6A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, GAT3, INO4, RAP1, YAP5 |
Main: | | biosynthesis (0.75) | structural constituent of ribosome (0.63) | cytoplasm (0.88) | FHL1 (0.67) |
Score: | | 0.67 | 0.40 | 0.78 | 0.590 |
P-value: | | 2.231E-08 (protein biosynthesis) | 4.607E-11 (structural constituent of ribosome) | 1.179E-12 (cytosolic ribosome (sensu Eukarya)) | 1.850E-14 (FHL1) |
RAP1(1) AND SWI5(1) => SimExpr(other) OR SimExpr(YLR344W) : 6 14
EXPR: (0.100) SWI5 (P < 0.000) RAP1 (P < 0.475)
ORF | SYMBOL | P | F | C | TF |
|YMR013C| | SEC59 | protein-ER targeting, protein amino acid glycosylation -> cell organization and biogenesis, biosynthesis, protein modification, protein metabolism, transport | dolichol kinase activity -> dolichol kinase activity | membrane -> membrane | FHL1, NDD1, RAP1, RLM1, RME1 |
|YLR452C| | SST2 | signal transduction, adaptation to pheromone during conjugation with cellular fusion -> signal transduction, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus | GTPase activator activity -> GTPase activator activity | plasma membrane -> membrane | DIG1, FHL1, RAP1, STE12 |
|YEL056W| | HAT2 | chromatin assembly/disassembly, chromatin silencing at telomere -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription | H3/H4 histone acetyltransferase activity -> acetyltransferase activity | cytoplasm, nucleus -> cytoplasm, nucleus | GAL4 |
YKL006W | RPL14A | protein biosynthesis -> biosynthesis, protein metabolism | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, GRF10(Pho2), GTS1, RAP1 |
YLR441C | RPS1A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, GAT3, RAP1, YAP5 |
YBR181C | RPS6B | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya), cytoplasm -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, GAT3, MAL13, RAP1, RGM1 |
YDR450W | RPS18A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, GAT3, HIR2, RAP1, RGM1, YAP5 |
YOR369C | RPS12 | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | ARG80, FHL1, FKH2, LEU3, NDD1, PDR1, RME1, SMP1, YAP6 |
YJR145C | RPS4A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya), cytoplasm -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | ACE2, CIN5, FHL1, INO4, MTH1, RAP1, YAP6 |
YBL087C | RPL23A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, IXR1, MSS11, PDR1, RAP1, SMP1, SOK2 |
|YDR406W| | PDR15 | transport -> transport | ATP-binding cassette (ABC) transporter activity -> ATPase activity, P-P-bond-hydrolysis-driven transporter activity, hydrolase activity\, acting on acid anhydrides\, catalyzing transmembrane movement of substances | integral to membrane -> membrane | |
YLR344W | RPL26A | protein biosynthesis -> biosynthesis, protein metabolism | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, RAP1 |
YGL030W | RPL30 | protein biosynthesis, rRNA processing, mRNA splicing, regulation of translation -> cell organization and biogenesis, biosynthesis, transcription, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya), cytoplasm -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, RAP1, SFP1 |
YKR092C | SRP40 | nucleocytoplasmic transport -> transport | chaperone activity -> chaperone activity | nucleolus -> nucleus | CUP9, MET4, RAP1 |
YER074W | RPS24A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, GAT3, PDR1, RAP1, RGM1, SMP1, YAP5 |
|YBR295W| | PCA1 | copper ion homeostasis -> cell homeostasis | P-type ATPase activity -> ATPase activity, P-P-bond-hydrolysis-driven transporter activity, cation transporter activity, hydrolase activity\, acting on acid anhydrides\, catalyzing transmembrane movement of substances | membrane -> membrane | GAL4, SMP1 |
YOR213C | SAS5 | chromatin silencing at telomere -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription | acetyltransferase activity -> acetyltransferase activity | nuclear chromosome\, telomeric region, nuclear chromatin -> chromosome, nuclear chromosome | GRF10(Pho2), SUM1 |
|YMR224C| | MRE11 | DNA repair, double-strand break repair via nonhomologous end-joining, meiotic DNA double-strand break formation, meiotic DNA double-strand break processing, double-strand break repair via break-induced replication -> DNA metabolism, cell proliferation, catabolism | endonuclease activity, 3'-5' exonuclease activity, protein binding -> endonuclease activity, 3'-5' exonuclease activity, protein binding | nucleus -> nucleus | RAP1 |
YLR249W | YEF3 | translational elongation -> biosynthesis, protein metabolism | translation elongation factor activity -> translation elongation factor activity | ribosome -> cytoplasm, ribonucleoprotein complex | INO2, INO4 |
YNL069C | RPL16B | protein biosynthesis -> biosynthesis, protein metabolism | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, PDR1, RAP1, RGM1, YAP5 |
Main: | | biosynthesis (0.65) | structural constituent of ribosome (0.55) | cytoplasm (0.65) | RAP1 (0.74) |
Score: | | 0.45 | 0.30 | 0.46 | 0.637 |
P-value: | | 1.090E-05 (protein biosynthesis) | 2.358E-06 (structural constituent of ribosome) | 1.313E-07 (cytosolic ribosome (sensu Eukarya)) | 1.232E-10 (FHL1) |
RAP1(1) AND MCM1'(1) => SimExpr(other) OR SimExpr(YLR344W) : 5 16
EXPR: (0.090) MCM1' (P < 0.000) RAP1 (P < 0.115)
ORF | SYMBOL | P | F | C | TF |
|YLR452C| | SST2 | signal transduction, adaptation to pheromone during conjugation with cellular fusion -> signal transduction, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus | GTPase activator activity -> small GTPase regulatory/interacting protein activity | plasma membrane -> plasma membrane | DIG1, FHL1, RAP1, STE12 |
|YBR117C| | TKL2 | pentose-phosphate shunt -> coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism | transketolase activity -> transferase activity\, transferring aldehyde or ketonic groups | | FHL1, RAP1 |
|YHL038C| | CBP2 | RNA splicing -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | pre-mRNA splicing factor activity -> RNA binding | mitochondrion -> cytoplasm | RAP1 |
YDL130W | RPP1B | protein biosynthesis, translational elongation -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, GAL4, RAP1, RFX1 |
YKL006W | RPL14A | protein biosynthesis -> biosynthesis, protein metabolism | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, GRF10(Pho2), GTS1, RAP1 |
YGL147C | RPL9A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, MBP1, RAP1, SWI4 |
YLR146C | SPE4 | pantothenate biosynthesis, spermine biosynthesis -> biosynthesis, amine metabolism, coenzymes and prosthetic group metabolism, amino acid and derivative metabolism, secondary metabolism | spermine synthase activity -> transferase activity\, transferring alkyl or aryl (other than methyl) groups | | |
YGR214W | RPS0A | protein biosynthesis, ribosomal small subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, RAP1 |
YDR450W | RPS18A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, GAT3, HIR2, RAP1, RGM1, YAP5 |
YLR061W | RPL22A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | BAS1, FHL1, HIR1, PDR1, RAP1, RCS1, RME1, ZAP1 |
YLR344W | RPL26A | protein biosynthesis -> biosynthesis, protein metabolism | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, RAP1 |
YKL152C | GPM1 | gluconeogenesis, glycolysis -> alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism | phosphoglycerate mutase activity -> intramolecular transferase activity | cytosol -> cytoplasm | GCR1, GCR2, HSF1, RAP1 |
YGL030W | RPL30 | protein biosynthesis, rRNA processing, mRNA splicing, regulation of translation -> cell organization and biogenesis, biosynthesis, transcription, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya), cytoplasm -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, RAP1, SFP1 |
YIL018W | RPL2B | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, PDR1, RAP1, RGM1, SWI5, YAP5 |
|YGR254W| | ENO1 | gluconeogenesis, glycolysis -> alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism | phosphopyruvate hydratase activity -> carbon-oxygen lyase activity | phosphopyruvate hydratase complex, cytoplasm -> cytoplasm | FKH2, MSN4, PDR1, SWI5, YAP5 |
YER074W | RPS24A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, GAT3, PDR1, RAP1, RGM1, SMP1, YAP5 |
YJR139C | HOM6 | homoserine biosynthesis, methionine metabolism, threonine metabolism -> amine metabolism, sulfur metabolism, biosynthesis, amino acid and derivative metabolism, organic acid metabolism | homoserine dehydrogenase activity -> oxidoreductase activity\, acting on CH-OH group of donors | | HMS1, RAP1 |
|YBL093C| | ROX3 | transcription from Pol II promoter -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | RNA polymerase II transcription mediator activity -> general RNA polymerase II transcription factor activity | mediator complex, nucleus -> nucleus | FHL1, RAP1 |
YGR085C | RPL11B | protein biosynthesis, ribosomal large subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, MIG1 |
YPL090C | RPS6A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, GAT3, INO4, RAP1, YAP5 |
YNL069C | RPL16B | protein biosynthesis -> biosynthesis, protein metabolism | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, PDR1, RAP1, RGM1, YAP5 |
Main: | | biosynthesis (0.81) | structural constituent of ribosome (0.62) | cytoplasm (0.89) | RAP1 (0.90) |
Score: | | 0.68 | 0.39 | 0.78 | 0.916 |
P-value: | | 2.807E-05 (biosynthesis) | 5.563E-09 (structural constituent of ribosome) | 5.032E-10 (cytosolic ribosome (sensu Eukarya)) | 1.578E-15 (RAP1) |
CSRE(1) AND RAP1(1) => SimExpr(other) OR SimExpr(YLR344W) : 2 9
RAP1(1) AND SCB(1) => SimExpr(YLR344W) OR SimExpr(other) : 8 1
EXPR: (0.084) SCB (P < 0.000) RAP1 (P < 0.119)
ORF | SYMBOL | P | F | C | TF |
|YLR208W| | SEC13 | nonselective vesicle assembly, ER to Golgi transport, ER-associated protein catabolism -> vesicle-mediated transport, intracellular transport, macromolecule catabolism, secretory pathway, protein metabolism | | cytoplasm, COPII vesicle coat, nuclear pore, extrinsic to plasma membrane -> nucleus, extrinsic to membrane, cytoplasm, membrane coat, integral to membrane, endomembrane system, plasma membrane | |
YOR369C | RPS12 | protein biosynthesis -> macromolecule biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | ARG80, FHL1, FKH2, LEU3, NDD1, PDR1, RME1, SMP1, YAP6 |
YPL131W | RPL5 | protein biosynthesis, ribosomal large subunit assembly and maintenance -> macromolecule biosynthesis, cytoplasm organization and biogenesis, protein metabolism | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, RAP1 |
YBL087C | RPL23A | protein biosynthesis -> macromolecule biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, IXR1, MSS11, PDR1, RAP1, SMP1, SOK2 |
YBR118W | TEF2 | translational elongation -> macromolecule biosynthesis, protein metabolism | translation elongation factor activity -> translation elongation factor activity | ribosome -> cytoplasm, ribonucleoprotein complex | FHL1, RAP1 |
YLR344W | RPL26A | protein biosynthesis -> macromolecule biosynthesis, protein metabolism | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, RAP1 |
YGR085C | RPL11B | protein biosynthesis, ribosomal large subunit assembly and maintenance -> macromolecule biosynthesis, cytoplasm organization and biogenesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, MIG1 |
YHL033C | RPL8A | protein biosynthesis -> macromolecule biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1 |
YLR249W | YEF3 | translational elongation -> macromolecule biosynthesis, protein metabolism | translation elongation factor activity -> translation elongation factor activity | ribosome -> cytoplasm, ribonucleoprotein complex | INO2, INO4 |
Main: | | protein metabolism (1.00) | structural constituent of ribosome (0.75) | cytoplasm (1.00) | FHL1 (0.88) |
Score: | | 1.00 | 0.57 | 1.00 | 0.750 |
P-value: | | 2.819E-05 (protein biosynthesis) | 2.238E-04 (structural constituent of ribosome) | 1.586E-06 (ribosome) | 1.471E-06 (FHL1) |
RAP1(1) AND SWI5(1) AND MCM1'(1) => SimExpr(YLR344W) OR SimExpr(other) : 6 1
EXPR: (0.070) SWI5 (P < 0.000) MCM1' (P < 0.000) RAP1 (P < 0.030)
ORF | SYMBOL | P | F | C | TF |
|YLR452C| | SST2 | signal transduction, adaptation to pheromone during conjugation with cellular fusion -> signal transduction, adaptation to pheromone during conjugation with cellular fusion | GTPase activator activity -> GTPase activator activity | plasma membrane -> plasma membrane | DIG1, FHL1, RAP1, STE12 |
YKL006W | RPL14A | protein biosynthesis -> protein biosynthesis | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytosolic ribosome (sensu Eukarya), large ribosomal subunit | FHL1, GAT3, GRF10(Pho2), GTS1, RAP1 |
YDR450W | RPS18A | protein biosynthesis -> protein biosynthesis | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> cytosolic ribosome (sensu Eukarya), eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, small ribosomal subunit | FHL1, GAT3, HIR2, RAP1, RGM1, YAP5 |
YLR344W | RPL26A | protein biosynthesis -> protein biosynthesis | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytosolic ribosome (sensu Eukarya), large ribosomal subunit | FHL1, RAP1 |
YGL030W | RPL30 | protein biosynthesis, rRNA processing, mRNA splicing, regulation of translation -> protein biosynthesis, rRNA processing, mRNA splicing, regulation of translation | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya), cytoplasm -> cytosolic ribosome (sensu Eukarya), cytoplasm, large ribosomal subunit | FHL1, GAT3, RAP1, SFP1 |
YER074W | RPS24A | protein biosynthesis -> protein biosynthesis | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> cytosolic ribosome (sensu Eukarya), eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, small ribosomal subunit | FHL1, GAT3, PDR1, RAP1, RGM1, SMP1, YAP5 |
YNL069C | RPL16B | protein biosynthesis -> protein biosynthesis | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytosolic ribosome (sensu Eukarya), large ribosomal subunit | FHL1, GAT3, PDR1, RAP1, RGM1, YAP5 |
Main: | | protein biosynthesis (0.86) | structural constituent of ribosome (0.86) | cytosolic ribosome (sensu Eukarya) (0.86) | RAP1 FHL1 (1.00) |
Score: | | 0.71 | 0.71 | 0.71 | 1.000 |
P-value: | | 5.608E-04 (protein biosynthesis) | 1.504E-05 (structural constituent of ribosome) | 8.648E-06 (cytosolic ribosome (sensu Eukarya)) | 3.457E-08 (FHL1) |
RAP1(1) AND ALPHA1'(1) AND MCM1'(1) => SimExpr(other) OR SimExpr(YLR344W) : 3 7
EXPR: (0.092) ALPHA1' (P < 0.000) MCM1' (P < 0.000) RAP1 (P < 0.281)
ORF | SYMBOL | P | F | C | TF |
|YBR117C| | TKL2 | pentose-phosphate shunt -> coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism | transketolase activity -> transferase activity\, transferring aldehyde or ketonic groups | | FHL1, RAP1 |
|YHL038C| | CBP2 | RNA splicing -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | pre-mRNA splicing factor activity -> RNA binding | mitochondrion -> cytoplasm | RAP1 |
YDL130W | RPP1B | protein biosynthesis, translational elongation -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, GAL4, RAP1, RFX1 |
YLR146C | SPE4 | pantothenate biosynthesis, spermine biosynthesis -> biosynthesis, amine metabolism, coenzymes and prosthetic group metabolism, amino acid and derivative metabolism, secondary metabolism | spermine synthase activity -> transferase activity\, transferring alkyl or aryl (other than methyl) groups | | |
YGR214W | RPS0A | protein biosynthesis, ribosomal small subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, RAP1 |
YLR061W | RPL22A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | BAS1, FHL1, HIR1, PDR1, RAP1, RCS1, RME1, ZAP1 |
YLR344W | RPL26A | protein biosynthesis -> biosynthesis, protein metabolism | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, RAP1 |
|YGR254W| | ENO1 | gluconeogenesis, glycolysis -> alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism | phosphopyruvate hydratase activity -> carbon-oxygen lyase activity | phosphopyruvate hydratase complex, cytoplasm -> cytoplasm | FKH2, MSN4, PDR1, SWI5, YAP5 |
YER074W | RPS24A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, GAT3, PDR1, RAP1, RGM1, SMP1, YAP5 |
YPL090C | RPS6A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, GAT3, INO4, RAP1, YAP5 |
Main: | | biosynthesis (0.80) | structural constituent of ribosome (0.60) | cytoplasm (1.00) | RAP1 (0.89) |
Score: | | 0.67 | 0.36 | 1.00 | 0.861 |
P-value: | | 2.315E-02 (biosynthesis) | 4.690E-04 (structural constituent of ribosome) | 2.195E-04 (cytosolic ribosome (sensu Eukarya)) | 2.612E-06 (RAP1) |
CSRE(1) AND RAP1(1) AND SWI5(1) => SimExpr(YLR344W) : 5
RAP1(1) AND ALPHA1'(1) AND SCB(1) => SimExpr(YLR344W) : 5
EXPR: (0.069) ALPHA1' (P < 0.000) SCB (P < 0.000) RAP1 (P < 0.053)
ORF | SYMBOL | P | F | C | TF |
YOR369C | RPS12 | protein biosynthesis -> protein biosynthesis | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> cytosol, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome | ARG80, FHL1, FKH2, LEU3, NDD1, PDR1, RME1, SMP1, YAP6 |
YPL131W | RPL5 | protein biosynthesis, ribosomal large subunit assembly and maintenance -> protein biosynthesis, ribosome biogenesis and assembly | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytosol, ribosome | FHL1, GAT3, RAP1 |
YBR118W | TEF2 | translational elongation -> protein biosynthesis | translation elongation factor activity -> translation elongation factor activity | ribosome -> ribosome | FHL1, RAP1 |
YLR344W | RPL26A | protein biosynthesis -> protein biosynthesis | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytosol, ribosome | FHL1, RAP1 |
YHL033C | RPL8A | protein biosynthesis -> protein biosynthesis | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytosol, ribosome | FHL1 |
Main: | | protein biosynthesis (1.00) | structural constituent of ribosome (0.80) | ribosome (1.00) | FHL1 (1.00) |
Score: | | 1.00 | 0.60 | 1.00 | 1.000 |
P-value: | | 5.595E-04 (protein biosynthesis) | 1.631E-03 (structural constituent of ribosome) | 1.672E-04 (ribosome) | 8.831E-06 (FHL1) |
RAP1(1) AND SFF'(1) AND SCB(1) => SimExpr(YLR344W) : 8
EXPR: (0.076) SFF' (P < 0.000) SCB (P < 0.000) RAP1 (P < 0.050)
ORF | SYMBOL | P | F | C | TF |
YOR369C | RPS12 | protein biosynthesis -> protein biosynthesis | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> cytosol, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome | ARG80, FHL1, FKH2, LEU3, NDD1, PDR1, RME1, SMP1, YAP6 |
YPL131W | RPL5 | protein biosynthesis, ribosomal large subunit assembly and maintenance -> protein biosynthesis, ribosome biogenesis and assembly | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytosol, ribosome | FHL1, GAT3, RAP1 |
YBL087C | RPL23A | protein biosynthesis -> protein biosynthesis | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytosol, ribosome | FHL1, IXR1, MSS11, PDR1, RAP1, SMP1, SOK2 |
YBR118W | TEF2 | translational elongation -> protein biosynthesis | translation elongation factor activity -> translation elongation factor activity | ribosome -> ribosome | FHL1, RAP1 |
YLR344W | RPL26A | protein biosynthesis -> protein biosynthesis | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytosol, ribosome | FHL1, RAP1 |
YGR085C | RPL11B | protein biosynthesis, ribosomal large subunit assembly and maintenance -> protein biosynthesis, ribosome biogenesis and assembly | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytosol, ribosome | FHL1, MIG1 |
YHL033C | RPL8A | protein biosynthesis -> protein biosynthesis | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytosol, ribosome | FHL1 |
YLR249W | YEF3 | translational elongation -> protein biosynthesis | translation elongation factor activity -> translation elongation factor activity | ribosome -> ribosome | INO2, INO4 |
Main: | | protein biosynthesis (1.00) | structural constituent of ribosome (0.75) | ribosome (1.00) | FHL1 (0.88) |
Score: | | 1.00 | 0.57 | 1.00 | 0.750 |
P-value: | | 3.588E-06 (protein biosynthesis) | 8.006E-05 (structural constituent of ribosome) | 1.941E-07 (ribosome) | 3.438E-07 (FHL1) |
MCB(1) AND SCB(1) => SimExpr(YCR065W) OR SimExpr(other) : 10 4
EXPR: (0.106) MCB (P < 0.070) SCB (P < 0.000)
ORF | SYMBOL | P | F | C | TF |
YNL082W | PMS1 | mismatch repair, meiosis -> DNA metabolism, cell proliferation | ATPase activity, ATP binding, DNA binding -> purine nucleotide binding, DNA binding, hydrolase activity\, acting on acid anhydrides | nuclear chromosome -> chromosome, nucleus | MTH1 |
YGL225W | VRG4 | nucleotide-sugar transport, N-linked glycosylation, lipid glycosylation -> transport, biosynthesis, lipid metabolism, protein metabolism | nucleotide-sugar transporter activity -> nucleotide-sugar transporter activity | Golgi apparatus -> cytoplasm | |
YOL006C | TOP1 | negative regulation of recombination within rDNA repeats, DNA topological change, DNA strand elongation, chromatin assembly/disassembly, regulation of transcription from Pol II promoter, RNA elongation from Pol II promoter, mitotic chromosome condensation, nuclear migration -> cell organization and biogenesis, cell cycle, mitotic cell cycle, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | DNA topoisomerase type I activity -> other isomerase activity | nucleus -> nucleus | REB1 |
YCR065W | HCM1 | spindle assembly, transcription initiation from Pol II promoter -> cell organization and biogenesis, cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | specific RNA polymerase II transcription factor activity -> specific RNA polymerase II transcription factor activity | nucleus -> nucleus | ASH1, HSF1, MBP1, NDD1, PHD1, ROX1, STB1, SWI4 |
YDR211W | GCD6 | translational initiation -> biosynthesis, protein metabolism | translation initiation factor activity -> translation factor activity\, nucleic acid binding | ribosome, eukaryotic translation initiation factor 2B complex -> cytoplasm, ribonucleoprotein complex | HSF1 |
|YDR297W| | SUR2 | sphingolipid metabolism, sphingolipid biosynthesis -> lipid metabolism, biosynthesis | sphingosine hydroxylase activity -> sphingosine hydroxylase activity | endoplasmic reticulum -> cytoplasm | CBF1, MTH1 |
|YKL042W| | SPC42 | microtubule nucleation, spindle pole body duplication (sensu Saccharomyces) -> cell organization and biogenesis, cell proliferation | structural constituent of cytoskeleton -> structural constituent of cytoskeleton | intermediate layer of spindle pole body, central plaque of spindle pole body -> cytoplasm | |
YBL035C | POL12 | DNA replication\, priming, DNA replication initiation, lagging strand elongation -> cell proliferation, cell cycle, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | alpha DNA polymerase activity -> transferase activity\, transferring phosphorus-containing groups | alpha DNA polymerase\:primase complex -> nucleus | MBP1 |
YIL066C | RNR3 | DNA replication -> cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | ribonucleoside-diphosphate reductase activity -> oxidoreductase activity\, acting on CH2 groups | cytoplasm -> cytoplasm | RFX1, STB1 |
YBR088C | POL30 | leading strand elongation, lagging strand elongation, mutagenesis, base-excision repair, nucleotide-excision repair, mismatch repair, postreplication repair -> cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, mitotic cell cycle | DNA polymerase processivity factor activity -> transferase activity\, transferring phosphorus-containing groups | replication fork -> nucleus | |
|YGR085C| | RPL11B | protein biosynthesis, ribosomal large subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, MIG1 |
|YML012W| | ERV25 | ER to Golgi transport -> transport, vesicle-mediated transport | | COPII-coated vesicle -> cytoplasm | ABF1 |
YER070W | RNR1 | DNA replication -> cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | ribonucleoside-diphosphate reductase activity -> oxidoreductase activity\, acting on CH2 groups | cytoplasm -> cytoplasm | FKH2, MBP1, REB1, SWI4, SWI6 |
YDR052C | DBF4 | DNA replication initiation, regulation of DNA replication, protein amino acid phosphorylation -> phosphorus metabolism, cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism | protein serine/threonine kinase activity -> transferase activity\, transferring phosphorus-containing groups | nucleoplasm -> nucleus | IME4, NRG1 |
Main: | | cell proliferation (0.57) | transferase activity\, transferring phosphorus-containing groups (0.23) | cytoplasm (0.57) | MBP1 (0.27) |
Score: | | 0.53 | 0.05 | 0.47 | 0.127 |
P-value: | | 4.340E-06 (DNA replication and chromosome cycle) | 7.486E-03 (oxidoreductase activity\, acting on CH2 groups\, disulfide as acceptor) | 4.996E-02 (replication fork) | 1.745E-01 (MBP1) |
ALPHA1'(1) AND MCB(1) AND SCB(1) => SimExpr(YCR065W) OR SimExpr(other) : 5 2
EXPR: (0.090) ALPHA1' (P < 0.000) MCB (P < 0.018) SCB (P < 0.000)
ORF | SYMBOL | P | F | C | TF |
YGL225W | VRG4 | nucleotide-sugar transport, N-linked glycosylation, lipid glycosylation -> transport, biosynthesis, lipid metabolism, protein metabolism | nucleotide-sugar transporter activity -> nucleotide-sugar transporter activity | Golgi apparatus -> cytoplasm | |
YOL006C | TOP1 | negative regulation of recombination within rDNA repeats, DNA topological change, DNA strand elongation, chromatin assembly/disassembly, regulation of transcription from Pol II promoter, RNA elongation from Pol II promoter, mitotic chromosome condensation, nuclear migration -> cell organization and biogenesis, cell cycle, mitotic cell cycle, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | DNA topoisomerase type I activity -> DNA topoisomerase type I activity | nucleus -> nucleus | REB1 |
YCR065W | HCM1 | spindle assembly, transcription initiation from Pol II promoter -> cell organization and biogenesis, cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | specific RNA polymerase II transcription factor activity -> specific RNA polymerase II transcription factor activity | nucleus -> nucleus | ASH1, HSF1, MBP1, NDD1, PHD1, ROX1, STB1, SWI4 |
|YDR297W| | SUR2 | sphingolipid metabolism, sphingolipid biosynthesis -> lipid metabolism, biosynthesis | sphingosine hydroxylase activity -> sphingosine hydroxylase activity | endoplasmic reticulum -> cytoplasm | CBF1, MTH1 |
|YKL042W| | SPC42 | microtubule nucleation, spindle pole body duplication (sensu Saccharomyces) -> cell organization and biogenesis, cell proliferation | structural constituent of cytoskeleton -> structural constituent of cytoskeleton | intermediate layer of spindle pole body, central plaque of spindle pole body -> cytoplasm | |
YIL066C | RNR3 | DNA replication -> cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | ribonucleoside-diphosphate reductase activity -> ribonucleoside-diphosphate reductase activity | cytoplasm -> cytoplasm | RFX1, STB1 |
YER070W | RNR1 | DNA replication -> cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | ribonucleoside-diphosphate reductase activity -> ribonucleoside-diphosphate reductase activity | cytoplasm -> cytoplasm | FKH2, MBP1, REB1, SWI4, SWI6 |
Main: | | cell proliferation (0.57) | ribonucleoside-diphosphate reductase activity (0.29) | cytoplasm (0.71) | SWI4 STB1 REB1 MBP1 (0.40) |
Score: | | 0.52 | 0.05 | 0.52 | 0.300 |
P-value: | | 6.514E-03 (DNA replication and chromosome cycle) | 8.678E-04 (oxidoreductase activity\, acting on CH2 groups\, disulfide as acceptor) | 2.431E+00 (intracellular) | 5.032E-02 (STB1) |
ALPHA1(1) AND ALPHA1'(1) AND MCB(1) => SimExpr(YCR065W) OR SimExpr(other) : 5 2
EXPR: (0.096) ALPHA1' (P < 0.000) MCB (P < 0.043) ALPHA1 (P < 0.000)
ORF | SYMBOL | P | F | C | TF |
YGL225W | VRG4 | nucleotide-sugar transport, N-linked glycosylation, lipid glycosylation -> transport, biosynthesis, lipid metabolism, protein metabolism | nucleotide-sugar transporter activity -> nucleotide-sugar transporter activity | Golgi apparatus -> cytoplasm | |
YDR097C | MSH6 | mismatch repair -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, cell proliferation | ATPase activity, ATP binding, DNA binding -> ATPase activity, ATP binding, DNA binding | nucleus -> nucleus | DOT6, MBP1, SWI6 |
YOL006C | TOP1 | negative regulation of recombination within rDNA repeats, DNA topological change, DNA strand elongation, chromatin assembly/disassembly, regulation of transcription from Pol II promoter, RNA elongation from Pol II promoter, mitotic chromosome condensation, nuclear migration -> cell organization and biogenesis, cell cycle, mitotic cell cycle, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | DNA topoisomerase type I activity -> DNA topoisomerase type I activity | nucleus -> nucleus | REB1 |
YCR065W | HCM1 | spindle assembly, transcription initiation from Pol II promoter -> cell organization and biogenesis, cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | specific RNA polymerase II transcription factor activity -> specific RNA polymerase II transcription factor activity | nucleus -> nucleus | ASH1, HSF1, MBP1, NDD1, PHD1, ROX1, STB1, SWI4 |
|YLR430W| | SEN1 | 35S primary transcript processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | ATP dependent RNA helicase activity -> RNA helicase activity, ATPase activity | nucleolus -> nucleus | ARG80, GTS1, HAP5, RTG3, SIP4 |
|YER047C| | SAP1 | | | | MSS11 |
YNL233W | BNI4 | cytokinesis -> cell proliferation | protein binding -> protein binding | contractile ring (sensu Saccharomyces) -> site of polarized growth (sensu Fungi), cell cortex, cytoplasm | PHO4 |
Main: | | nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.67) | ATPase activity (0.33) | nucleus (0.67) | MBP1 (0.33) |
Score: | | 0.53 | 0.07 | 0.47 | 0.067 |
P-value: | | 1.178E-01 (cell proliferation) | 6.480E-01 (ATP binding) | 9.201E-01 (nucleus) | 3.556E-01 (MBP1) |
MCM1(1) AND MCB(1) => SimExpr(YCR065W) : 6
EXPR: (0.092) MCB (P < 0.032) MCM1 (P < 0.000)
ORF | SYMBOL | P | F | C | TF |
YGR109C | CLB6 | regulation of CDK activity, G1/S transition of mitotic cell cycle, premeiotic DNA synthesis -> cell cycle, mitotic cell cycle, DNA metabolism | cyclin-dependent protein kinase\, regulator activity -> cyclin-dependent protein kinase\, regulator activity | | MBP1, STB1, SWI4, SWI6 |
YCR065W | HCM1 | spindle assembly, transcription initiation from Pol II promoter -> cytoplasm organization and biogenesis, cell cycle, transcription | specific RNA polymerase II transcription factor activity -> specific RNA polymerase II transcription factor activity | nucleus -> nucleus | ASH1, HSF1, MBP1, NDD1, PHD1, ROX1, STB1, SWI4 |
YDR309C | GIC2 | axial budding, Rho protein signal transduction, establishment of cell polarity (sensu Saccharomyces) -> budding, intracellular signaling cascade, cytoplasm organization and biogenesis | small GTPase regulatory/interacting protein activity -> small GTPase regulatory/interacting protein activity | actin cap (sensu Saccharomyces), bud tip, shmoo tip, incipient bud site -> cell cortex, site of polarized growth (sensu Fungi), incipient bud site, cytoplasm | ASH1, HSF1, MBP1, PHD1, RLM1, SKN7, STB1, STE12, SWI4, SWI6 |
YIL066C | RNR3 | DNA replication -> cell cycle, DNA metabolism | ribonucleoside-diphosphate reductase activity -> ribonucleoside-diphosphate reductase activity | cytoplasm -> cytoplasm | RFX1, STB1 |
YNR028W | CPR8 | | peptidyl-prolyl cis-trans isomerase activity -> peptidyl-prolyl cis-trans isomerase activity | | ASH1, DIG1, MCM1 |
YGL163C | RAD54 | double-strand break repair via synthesis-dependent strand annealing, heteroduplex formation, double-strand break repair via break-induced replication, telomerase-independent telomere maintenance, double-strand break repair via single-strand annealing, chromatin modeling -> mating-type switching/recombination, chromosome organization and biogenesis (sensu Eukarya), DNA repair, response to DNA damage, DNA metabolism | DNA supercoiling activity, DNA dependent ATPase activity -> DNA supercoiling activity, DNA dependent ATPase activity | nucleus -> nucleus | |
Main: | | DNA metabolism (0.60) | peptidyl-prolyl cis-trans isomerase activity (0.17) | cytoplasm (0.50) | STB1 (0.80) |
Score: | | 0.60 | 0.00 | 0.33 | 0.800 |
P-value: | | 2.557E-01 (DNA metabolism) | 1.199E+00 (enzyme activity) | 3.742E+00 (nucleus) | 5.347E-06 (STB1) |
STE12(1) AND MCB(1) => SimExpr(YCR065W) : 5
EXPR: (0.085) STE12 (P < 0.000) MCB (P < 0.013)
ORF | SYMBOL | P | F | C | TF |
YCR065W | HCM1 | spindle assembly, transcription initiation from Pol II promoter -> cell organization and biogenesis, cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | specific RNA polymerase II transcription factor activity -> specific RNA polymerase II transcription factor activity | nucleus -> nucleus | ASH1, HSF1, MBP1, NDD1, PHD1, ROX1, STB1, SWI4 |
YDR309C | GIC2 | axial budding, Rho protein signal transduction, establishment of cell polarity (sensu Saccharomyces) -> asexual reproduction, signal transduction, cell organization and biogenesis | small GTPase regulatory/interacting protein activity -> small GTPase regulatory/interacting protein activity | actin cap (sensu Saccharomyces), bud tip, shmoo tip, incipient bud site -> cell cortex, site of polarized growth (sensu Fungi), incipient bud site, cytoplasm | ASH1, HSF1, MBP1, PHD1, RLM1, SKN7, STB1, STE12, SWI4, SWI6 |
YJR043C | POL32 | leading strand elongation, lagging strand elongation, mutagenesis, base-excision repair, nucleotide-excision repair, mismatch repair, postreplication repair -> cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, mitotic cell cycle | delta DNA polymerase activity -> delta DNA polymerase activity | delta DNA polymerase complex, nucleus -> cytoplasm, nucleus | MOT3, RTS2 |
YNL233W | BNI4 | cytokinesis -> cell proliferation | protein binding -> protein binding | contractile ring (sensu Saccharomyces) -> site of polarized growth (sensu Fungi), cell cortex, cytoplasm | PHO4 |
YPR135W | CTF4 | DNA dependent DNA replication, DNA repair -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, cell proliferation | DNA binding -> DNA binding | nucleus -> nucleus | BAS1, DIG1, FZF1 |
Main: | | cell proliferation (0.80) | DNA binding (0.20) | cytoplasm (0.60) | SWI4 STB1 ASH1 HSF1 PHD1 MBP1 (0.40) |
Score: | | 0.70 | 0.00 | 0.60 | 0.100 |
P-value: | | 1.957E-02 (cell proliferation) | 1.354E+00 (binding) | 5.936E-02 (cell cortex) | 2.046E-02 (ASH1) |
HAP234(1) AND ALPHA1'(1) => SimExpr(YBL099W) OR SimExpr(other) : 9 4
EXPR: (0.111) ALPHA1' (P < 0.000) HAP234 (P < 0.122)
ORF | SYMBOL | P | F | C | TF |
YLR304C | ACO1 | tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis, propionate metabolism -> carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis | aconitate hydratase activity -> aconitate hydratase activity | cytosol, mitochondrial matrix -> cytoplasm | CIN5, YAP6 |
YOR136W | IDH2 | tricarboxylic acid cycle, isocitrate metabolism, glutamate biosynthesis -> carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis | isocitrate dehydrogenase (NAD+) activity -> isocitrate dehydrogenase activity | mitochondrial matrix, mitochondrion -> cytoplasm | MET4 |
|YCR069W| | CPR4 | | peptidyl-prolyl cis-trans isomerase activity -> peptidyl-prolyl cis-trans isomerase activity | membrane -> membrane | SKO1 |
|YBR118W| | TEF2 | translational elongation -> biosynthesis, protein metabolism | translation elongation factor activity -> translation elongation factor activity | ribosome -> cytoplasm, ribonucleoprotein complex | FHL1, RAP1 |
YLR038C | COX12 | cytochrome c oxidase biogenesis -> protein metabolism | cytochrome c oxidase activity -> heme-copper terminal oxidase activity, oxidoreductase activity\, acting on heme group of donors\, oxygen as acceptor, primary active transporter activity, hydrogen ion transporter activity | respiratory chain complex IV (sensu Eukarya) -> cytoplasm, respiratory chain complex IV, membrane | HAP4 |
YEL024W | RIP1 | aerobic respiration, oxidative phosphorylation\, ubiquinone to cytochrome c -> energy pathways, electron transport, phosphorus metabolism | ubiquinol-cytochrome c reductase activity -> oxidoreductase activity\, acting on diphenols and related substances as donors\, cytochrome as acceptor, primary active transporter activity, hydrogen ion transporter activity | respiratory chain complex III (sensu Eukarya) -> cytoplasm, respiratory chain complex III, membrane | CBF1, HAP2, HAP4 |
|YMR280C| | CAT8 | gluconeogenesis, positive regulation of transcription from Pol II promoter -> alcohol metabolism, monosaccharide metabolism, carbohydrate metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, biosynthesis, energy pathways | specific RNA polymerase II transcription factor activity -> specific RNA polymerase II transcription factor activity | nucleus -> nucleus | ABF1, REB1 |
YBL099W | ATP1 | ATP synthesis coupled proton transport -> transport | hydrogen-transporting ATP synthase activity -> hydrogen ion transporter activity | proton-transporting ATP synthase\, catalytic core (sensu Eukarya) -> cytoplasm, proton-transporting ATP synthase complex, membrane | HAP4, ROX1 |
YPR145W | ASN1 | asparagine biosynthesis -> amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis | asparagine synthase (glutamine-hydrolyzing) activity -> asparagine synthase (glutamine-hydrolyzing) activity | | DAL81, GCN4, GLN3, MET4, RAP1, SUM1 |
YKL141W | SDH3 | oxidative phosphorylation\, succinate to ubiquinone, tricarboxylic acid cycle -> electron transport, carbohydrate metabolism, phosphorus metabolism, energy pathways | succinate dehydrogenase activity -> succinate dehydrogenase activity | respiratory chain complex II (sensu Eukarya) -> cytoplasm, respiratory chain complex II, succinate dehydrogenase complex (ubiquinone), membrane | |
YML028W | TSA1 | response to oxidative stress, regulation of redox homeostasis -> oxygen and reactive oxygen species metabolism, cell homeostasis, response to biotic stimulus | thioredoxin peroxidase activity -> thioredoxin peroxidase activity | cytoplasm -> cytoplasm | MBP1, NDD1, SKN7, YAP1 |
YOR187W | TUF1 | translational elongation -> biosynthesis, protein metabolism | translation elongation factor activity -> translation elongation factor activity | mitochondrial matrix, mitochondrial ribosome -> cytoplasm, ribonucleoprotein complex | HAP4, REB1 |
|YHR018C| | ARG4 | arginine biosynthesis -> amine metabolism, nitrogen metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis | argininosuccinate lyase activity -> argininosuccinate lyase activity | cytosol -> cytoplasm | GCN4, INO2 |
Main: | | biosynthesis (0.58) | hydrogen ion transporter activity (0.23) | cytoplasm (0.83) | HAP4 (0.33) |
Score: | | 0.45 | 0.05 | 0.74 | 0.152 |
P-value: | | 1.352E-03 (tricarboxylic acid cycle) | 2.089E-02 (hydrogen ion transporter activity) | 5.530E-03 (mitochondrial electron transport chain) | 2.211E-03 (HAP4) |
RAP1(1) => SimExpr(other) OR SimExpr(YGR085C) : 16 35
RAP1(1) AND SCB(1) => SimExpr(YGR085C) OR SimExpr(other) : 8 1
RAP1(1) AND SFF'(1) AND SCB(1) => SimExpr(YGR085C) : 8
RAP1(1) AND ALPHA1(1) AND SCB(1) => SimExpr(YGR085C) : 5
EXPR: (0.059) SCB (P < 0.000) RAP1 (P < 0.074) ALPHA1 (P < 0.000)
ORF | SYMBOL | P | F | C | TF |
YPL131W | RPL5 | protein biosynthesis, ribosomal large subunit assembly and maintenance -> protein biosynthesis, ribosome biogenesis and assembly | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytosol, ribosome | FHL1, GAT3, RAP1 |
YBL087C | RPL23A | protein biosynthesis -> protein biosynthesis | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytosol, ribosome | FHL1, IXR1, MSS11, PDR1, RAP1, SMP1, SOK2 |
YGR085C | RPL11B | protein biosynthesis, ribosomal large subunit assembly and maintenance -> protein biosynthesis, ribosome biogenesis and assembly | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytosol, ribosome | FHL1, MIG1 |
YHL033C | RPL8A | protein biosynthesis -> protein biosynthesis | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytosol, ribosome | FHL1 |
YLR249W | YEF3 | translational elongation -> protein biosynthesis | translation elongation factor activity -> translation elongation factor activity | ribosome -> ribosome | INO2, INO4 |
Main: | | protein biosynthesis (1.00) | structural constituent of ribosome (0.80) | ribosome (1.00) | FHL1 (0.80) |
Score: | | 1.00 | 0.60 | 1.00 | 0.600 |
P-value: | | 1.119E-03 (protein biosynthesis) | 1.398E-03 (structural constituent of ribosome) | 1.008E-04 (cytosolic large ribosomal subunit (sensu Eukarya)) | 7.160E-04 (FHL1) |
mRRPE(1) AND PAC(1) => SimExpr(YOR095C) OR SimExpr(other) : 26 3
SFF'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YOR095C) OR SimExpr(other) : 9 2
EXPR: (0.094) SFF' (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.015)
ORF | SYMBOL | P | F | C | TF |
|YGL016W| | KAP122 | protein-nucleus import, response to drug -> response to abiotic stimulus, protein metabolism, transport | protein carrier activity -> transporter activity | cytoplasm, nuclear pore -> cytoplasm, nucleus, integral to membrane, endomembrane system | MSN2 |
YBR104W | YMC2 | transport -> transport | transporter activity -> transporter activity | mitochondrial inner membrane -> cytoplasm, inner membrane | FKH1, FKH2 |
YJL033W | HCA4 | 35S primary transcript processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | ATP dependent RNA helicase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides | nucleolus -> nucleus | HIR2, USV1 |
YJL138C | TIF2 | translational initiation, regulation of translational initiation -> biosynthesis, protein metabolism | translation initiation factor activity, RNA helicase activity -> translation factor activity\, nucleic acid binding, RNA binding | ribosome, cytoplasm -> cytoplasm, ribonucleoprotein complex | PHD1 |
YER110C | KAP123 | protein-nucleus import -> protein metabolism, transport | protein carrier activity -> transporter activity | cytoplasm, nuclear pore, nucleus -> cytoplasm, nucleus, integral to membrane, endomembrane system | |
YNL112W | DBP2 | | RNA helicase activity -> RNA binding | bud neck -> site of polarized growth (sensu Fungi) | |
|YNL292W| | PUS4 | tRNA modification -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | pseudouridylate synthase activity -> carbon-oxygen lyase activity | mitochondrion, nucleus -> cytoplasm, nucleus | RCS1 |
YOR310C | NOP58 | rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription | | small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex | ABF1, SWI6 |
YOR095C | RKI1 | pentose-phosphate shunt -> coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism | ribose-5-phosphate isomerase activity -> intramolecular isomerase activity | | FHL1, FKH2, RAP1 |
YGL078C | DBP3 | ribosomal large subunit assembly and maintenance, 35S primary transcript processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | ATP dependent RNA helicase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides | nucleolus -> nucleus | |
YLR249W | YEF3 | translational elongation -> biosynthesis, protein metabolism | translation elongation factor activity -> translation factor activity\, nucleic acid binding | ribosome -> cytoplasm, ribonucleoprotein complex | INO2, INO4 |
Main: | | nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.40) | RNA binding (0.40) | cytoplasm (0.60) | FKH2 (0.25) |
Score: | | 0.31 | 0.22 | 0.64 | 0.036 |
P-value: | | 1.087E-02 (35S primary transcript processing) | 9.534E-05 (RNA helicase activity) | 6.271E-02 (nucleolus) | 5.897E-01 (FKH2) |
RAP1(1) AND SCB(1) => SimExpr(YBR118W) OR SimExpr(other) : 8 1
RAP1(1) AND SFF'(1) AND SCB(1) => SimExpr(YBR118W) : 8
RAP1(1) AND ALPHA1'(1) AND SCB(1) => SimExpr(YBR118W) : 5
RAP1(1) AND SWI5(1) => SimExpr(other) OR SimExpr(YER074W) : 6 14
RAP1(1) AND SWI5(1) AND MCM1'(1) => SimExpr(YER074W) OR SimExpr(other) : 6 1
RAP1(1) AND ALPHA1(1) AND SWI5(1) => SimExpr(other) OR SimExpr(YER074W) : 2 6
EXPR: (0.106) SWI5 (P < 0.002) RAP1 (P < 0.729) ALPHA1 (P < 0.001)
ORF | SYMBOL | P | F | C | TF |
|YMR013C| | SEC59 | protein-ER targeting, protein amino acid glycosylation -> cytoplasm organization and biogenesis, macromolecule biosynthesis, intracellular transport, secretory pathway, protein modification, glycoprotein metabolism, protein metabolism, protein transport | dolichol kinase activity -> dolichol kinase activity | membrane -> membrane | FHL1, NDD1, RAP1, RLM1, RME1 |
YKL006W | RPL14A | protein biosynthesis -> macromolecule biosynthesis, protein metabolism | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, GRF10(Pho2), GTS1, RAP1 |
YBL087C | RPL23A | protein biosynthesis -> macromolecule biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, IXR1, MSS11, PDR1, RAP1, SMP1, SOK2 |
YKR092C | SRP40 | nucleocytoplasmic transport -> intracellular transport | chaperone activity -> chaperone activity | nucleolus -> nucleus | CUP9, MET4, RAP1 |
YER074W | RPS24A | protein biosynthesis -> macromolecule biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, GAT3, PDR1, RAP1, RGM1, SMP1, YAP5 |
YOR213C | SAS5 | chromatin silencing at telomere -> nuclear organization and biogenesis, gene silencing, DNA metabolism, transcription | acetyltransferase activity -> acetyltransferase activity | nuclear chromosome\, telomeric region, nuclear chromatin -> chromosome, nuclear chromosome | GRF10(Pho2), SUM1 |
|YMR224C| | MRE11 | DNA repair, double-strand break repair via nonhomologous end-joining, meiotic DNA double-strand break formation, meiotic DNA double-strand break processing, double-strand break repair via break-induced replication -> DNA recombination, cell cycle, catabolism, DNA metabolism | endonuclease activity, 3'-5' exonuclease activity, protein binding -> endonuclease activity, 3'-5' exonuclease activity, protein binding | nucleus -> nucleus | RAP1 |
YLR249W | YEF3 | translational elongation -> macromolecule biosynthesis, protein metabolism | translation elongation factor activity -> translation elongation factor activity | ribosome -> cytoplasm, ribonucleoprotein complex | INO2, INO4 |
Main: | | protein metabolism (0.62) | structural constituent of ribosome (0.38) | cytoplasm (0.50) | RAP1 (0.75) |
Score: | | 0.43 | 0.11 | 0.25 | 0.571 |
P-value: | | 3.994E-02 (protein biosynthesis) | 1.967E-01 (structural constituent of ribosome) | 8.363E-02 (ribosome) | 2.439E-04 (RAP1) |
RAP1(1) => SimExpr(other) OR SimExpr(YGL076C) : 15 36
RAP1(1) AND SCB(1) => SimExpr(YHL033C) OR SimExpr(other) : 8 1
RAP1(1) AND ALPHA1'(1) AND SCB(1) => SimExpr(YHL033C) : 5
RAP1(1) AND ALPHA1(1) AND SCB(1) => SimExpr(YHL033C) : 5
RAP1(1) AND SFF'(1) AND SCB(1) => SimExpr(YHL033C) : 8
RAP1(1) => SimExpr(other) OR SimExpr(YOR369C) : 16 35
RAP1(1) AND SFF(1) => SimExpr(other) OR SimExpr(YOR369C) : 9 22
EXPR: (0.093) SFF (P < 0.000) RAP1 (P < 0.313)
ORF | SYMBOL | P | F | C | TF |
YOL121C | RPS19A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | AZF1, FHL1, GCR1, GCR2, HAL9, MET31, MOT3, PDR1, RAP1, ROX1, RPH1, SMP1, YAP6, ZAP1 |
|YLR452C| | SST2 | signal transduction, adaptation to pheromone during conjugation with cellular fusion -> signal transduction, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus | GTPase activator activity -> GTPase activator activity | plasma membrane -> membrane | DIG1, FHL1, RAP1, STE12 |
|YLR208W| | SEC13 | nonselective vesicle assembly, ER to Golgi transport, ER-associated protein catabolism -> macromolecule catabolism, transport, protein metabolism | | cytoplasm, COPII vesicle coat, nuclear pore, extrinsic to plasma membrane -> nucleus, cytoplasm, membrane coat, membrane | |
YKR057W | RPS21A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | ABF1, FHL1 |
YKL006W | RPL14A | protein biosynthesis -> biosynthesis, protein metabolism | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, GRF10(Pho2), GTS1, RAP1 |
YLR441C | RPS1A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, GAT3, RAP1, YAP5 |
|YLR146C| | SPE4 | pantothenate biosynthesis, spermine biosynthesis -> biosynthesis, amine metabolism, coenzymes and prosthetic group metabolism, amino acid and derivative metabolism, secondary metabolism | spermine synthase activity -> spermine synthase activity | | |
YGR214W | RPS0A | protein biosynthesis, ribosomal small subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, RAP1 |
YJR123W | RPS5 | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, GRF10(Pho2), HSF1, MSN4, YAP1 |
YOR369C | RPS12 | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | ARG80, FHL1, FKH2, LEU3, NDD1, PDR1, RME1, SMP1, YAP6 |
YPL131W | RPL5 | protein biosynthesis, ribosomal large subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, RAP1 |
YJR145C | RPS4A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya), cytoplasm -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | ACE2, CIN5, FHL1, INO4, MTH1, RAP1, YAP6 |
YBL087C | RPL23A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, IXR1, MSS11, PDR1, RAP1, SMP1, SOK2 |
|YDR406W| | PDR15 | transport -> transport | ATP-binding cassette (ABC) transporter activity -> ATPase activity\, coupled to transmembrane movement of substances, P-P-bond-hydrolysis-driven transporter activity | integral to membrane -> membrane | |
YLR061W | RPL22A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | BAS1, FHL1, HIR1, PDR1, RAP1, RCS1, RME1, ZAP1 |
YDR418W | RPL12B | protein biosynthesis, ribosomal large subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, PDR1, RAP1, SMP1 |
YLR344W | RPL26A | protein biosynthesis -> biosynthesis, protein metabolism | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, RAP1 |
YKL152C | GPM1 | gluconeogenesis, glycolysis -> alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism | phosphoglycerate mutase activity -> phosphoglycerate mutase activity | cytosol -> cytoplasm | GCR1, GCR2, HSF1, RAP1 |
|YMR231W| | PEP5 | nonselective vesicle docking, homotypic vacuole fusion (non-autophagic), Golgi to endosome transport, late endosome to vacuole transport -> cell organization and biogenesis, transport, vesicle-mediated transport | | vacuolar membrane (sensu Fungi) -> cytoplasm, vacuole | ARG81, DOT6, HAL9, HAP2, MCM1, YAP1 |
|YGR254W| | ENO1 | gluconeogenesis, glycolysis -> alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism | phosphopyruvate hydratase activity -> phosphopyruvate hydratase activity | phosphopyruvate hydratase complex, cytoplasm -> cytoplasm | FKH2, MSN4, PDR1, SWI5, YAP5 |
YKR092C | SRP40 | nucleocytoplasmic transport -> transport | chaperone activity -> chaperone activity | nucleolus -> nucleus | CUP9, MET4, RAP1 |
YER074W | RPS24A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, GAT3, PDR1, RAP1, RGM1, SMP1, YAP5 |
YJR139C | HOM6 | homoserine biosynthesis, methionine metabolism, threonine metabolism -> amine metabolism, sulfur metabolism, biosynthesis, amino acid and derivative metabolism, organic acid metabolism | homoserine dehydrogenase activity -> homoserine dehydrogenase activity | | HMS1, RAP1 |
|YBR295W| | PCA1 | copper ion homeostasis -> cell homeostasis | P-type ATPase activity -> ATPase activity\, coupled to transmembrane movement of substances, P-P-bond-hydrolysis-driven transporter activity, cation transporter activity | membrane -> membrane | GAL4, SMP1 |
YKL180W | RPL17A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya), cytoplasm -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, RAP1 |
|YBL093C| | ROX3 | transcription from Pol II promoter -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | RNA polymerase II transcription mediator activity -> RNA polymerase II transcription mediator activity | mediator complex, nucleus -> nucleus | FHL1, RAP1 |
YGR085C | RPL11B | protein biosynthesis, ribosomal large subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, MIG1 |
|YMR224C| | MRE11 | DNA repair, double-strand break repair via nonhomologous end-joining, meiotic DNA double-strand break formation, meiotic DNA double-strand break processing, double-strand break repair via break-induced replication -> DNA metabolism, cell proliferation, catabolism | endonuclease activity, 3'-5' exonuclease activity, protein binding -> endonuclease activity, 3'-5' exonuclease activity, protein binding | nucleus -> nucleus | RAP1 |
YHL033C | RPL8A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1 |
YLR249W | YEF3 | translational elongation -> biosynthesis, protein metabolism | translation elongation factor activity -> translation elongation factor activity | ribosome -> cytoplasm, ribonucleoprotein complex | INO2, INO4 |
YNL069C | RPL16B | protein biosynthesis -> biosynthesis, protein metabolism | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, PDR1, RAP1, RGM1, YAP5 |
Main: | | biosynthesis (0.74) | structural constituent of ribosome (0.62) | cytoplasm (0.79) | FHL1 (0.71) |
Score: | | 0.61 | 0.38 | 0.65 | 0.725 |
P-value: | | 9.552E-08 (protein biosynthesis) | 1.976E-11 (structural constituent of ribosome) | 2.499E-13 (cytosolic ribosome (sensu Eukarya)) | 1.196E-16 (FHL1) |
RAP1(1) AND SFF'(1) => SimExpr(other) OR SimExpr(YOR369C) : 12 27
EXPR: (0.098) SFF' (P < 0.000) RAP1 (P < 0.534)
ORF | SYMBOL | P | F | C | TF |
|YMR013C| | SEC59 | protein-ER targeting, protein amino acid glycosylation -> cell organization and biogenesis, biosynthesis, protein modification, protein metabolism, transport | dolichol kinase activity -> dolichol kinase activity | membrane -> membrane | FHL1, NDD1, RAP1, RLM1, RME1 |
YOL121C | RPS19A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | AZF1, FHL1, GCR1, GCR2, HAL9, MET31, MOT3, PDR1, RAP1, ROX1, RPH1, SMP1, YAP6, ZAP1 |
|YLR452C| | SST2 | signal transduction, adaptation to pheromone during conjugation with cellular fusion -> signal transduction, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus | GTPase activator activity -> GTPase activator activity | plasma membrane -> membrane | DIG1, FHL1, RAP1, STE12 |
|YBL022C| | PIM1 | proteolysis and peptidolysis, response to heat -> catabolism, response to abiotic stimulus, protein metabolism | ATP-dependent peptidase activity -> ATP-dependent peptidase activity | mitochondrial matrix -> cytoplasm | RAP1 |
|YBR117C| | TKL2 | pentose-phosphate shunt -> coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism | transketolase activity -> transketolase activity | | FHL1, RAP1 |
YKR057W | RPS21A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | ABF1, FHL1 |
YKL006W | RPL14A | protein biosynthesis -> biosynthesis, protein metabolism | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, GRF10(Pho2), GTS1, RAP1 |
YGL147C | RPL9A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, MBP1, RAP1, SWI4 |
YLR441C | RPS1A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, GAT3, RAP1, YAP5 |
|YLR146C| | SPE4 | pantothenate biosynthesis, spermine biosynthesis -> biosynthesis, amine metabolism, coenzymes and prosthetic group metabolism, amino acid and derivative metabolism, secondary metabolism | spermine synthase activity -> spermine synthase activity | | |
YGR214W | RPS0A | protein biosynthesis, ribosomal small subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, RAP1 |
YJR123W | RPS5 | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, GRF10(Pho2), HSF1, MSN4, YAP1 |
YDL136W | RPL35B | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, INO4, MSS11, RAP1 |
YOR369C | RPS12 | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | ARG80, FHL1, FKH2, LEU3, NDD1, PDR1, RME1, SMP1, YAP6 |
YPL131W | RPL5 | protein biosynthesis, ribosomal large subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, RAP1 |
YJR145C | RPS4A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya), cytoplasm -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | ACE2, CIN5, FHL1, INO4, MTH1, RAP1, YAP6 |
YBL087C | RPL23A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, IXR1, MSS11, PDR1, RAP1, SMP1, SOK2 |
|YDR406W| | PDR15 | transport -> transport | ATP-binding cassette (ABC) transporter activity -> ATPase activity\, coupled to transmembrane movement of substances, P-P-bond-hydrolysis-driven transporter activity | integral to membrane -> membrane | |
YBR118W | TEF2 | translational elongation -> biosynthesis, protein metabolism | translation elongation factor activity -> translation elongation factor activity | ribosome -> cytoplasm, ribonucleoprotein complex | FHL1, RAP1 |
YLR061W | RPL22A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | BAS1, FHL1, HIR1, PDR1, RAP1, RCS1, RME1, ZAP1 |
YDR418W | RPL12B | protein biosynthesis, ribosomal large subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, PDR1, RAP1, SMP1 |
YLR344W | RPL26A | protein biosynthesis -> biosynthesis, protein metabolism | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, RAP1 |
YKL152C | GPM1 | gluconeogenesis, glycolysis -> alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism | phosphoglycerate mutase activity -> phosphoglycerate mutase activity | cytosol -> cytoplasm | GCR1, GCR2, HSF1, RAP1 |
|YMR231W| | PEP5 | nonselective vesicle docking, homotypic vacuole fusion (non-autophagic), Golgi to endosome transport, late endosome to vacuole transport -> cell organization and biogenesis, transport, vesicle-mediated transport | | vacuolar membrane (sensu Fungi) -> cytoplasm, vacuole | ARG81, DOT6, HAL9, HAP2, MCM1, YAP1 |
|YGR254W| | ENO1 | gluconeogenesis, glycolysis -> alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism | phosphopyruvate hydratase activity -> phosphopyruvate hydratase activity | phosphopyruvate hydratase complex, cytoplasm -> cytoplasm | FKH2, MSN4, PDR1, SWI5, YAP5 |
YKR092C | SRP40 | nucleocytoplasmic transport -> transport | chaperone activity -> chaperone activity | nucleolus -> nucleus | CUP9, MET4, RAP1 |
YGL076C | RPL7A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | |
YER074W | RPS24A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, GAT3, PDR1, RAP1, RGM1, SMP1, YAP5 |
YBR048W | RPS11B | protein biosynthesis, ribosomal small subunit assembly and maintenance, regulation of translational fidelity -> cell organization and biogenesis, biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | GAL4, HAP4, LEU3, MET31, MSN1 |
YJR139C | HOM6 | homoserine biosynthesis, methionine metabolism, threonine metabolism -> amine metabolism, sulfur metabolism, biosynthesis, amino acid and derivative metabolism, organic acid metabolism | homoserine dehydrogenase activity -> homoserine dehydrogenase activity | | HMS1, RAP1 |
|YBR295W| | PCA1 | copper ion homeostasis -> cell homeostasis | P-type ATPase activity -> ATPase activity\, coupled to transmembrane movement of substances, P-P-bond-hydrolysis-driven transporter activity, cation transporter activity | membrane -> membrane | GAL4, SMP1 |
YKL180W | RPL17A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya), cytoplasm -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, RAP1 |
|YBL093C| | ROX3 | transcription from Pol II promoter -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | RNA polymerase II transcription mediator activity -> RNA polymerase II transcription mediator activity | mediator complex, nucleus -> nucleus | FHL1, RAP1 |
YGR085C | RPL11B | protein biosynthesis, ribosomal large subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, MIG1 |
|YMR224C| | MRE11 | DNA repair, double-strand break repair via nonhomologous end-joining, meiotic DNA double-strand break formation, meiotic DNA double-strand break processing, double-strand break repair via break-induced replication -> DNA metabolism, cell proliferation, catabolism | endonuclease activity, 3'-5' exonuclease activity, protein binding -> endonuclease activity, 3'-5' exonuclease activity, protein binding | nucleus -> nucleus | RAP1 |
|YMR193W| | MRPL24 | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | mitochondrial large ribosomal subunit -> cytoplasm, ribonucleoprotein complex | ARO80, HAP4, HAP5, LEU3, MET31, RTG1, RTG3, STE12, STP1, UGA3 |
YHL033C | RPL8A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1 |
YLR249W | YEF3 | translational elongation -> biosynthesis, protein metabolism | translation elongation factor activity -> translation elongation factor activity | ribosome -> cytoplasm, ribonucleoprotein complex | INO2, INO4 |
YNL069C | RPL16B | protein biosynthesis -> biosynthesis, protein metabolism | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, PDR1, RAP1, RGM1, YAP5 |
Main: | | biosynthesis (0.77) | structural constituent of ribosome (0.61) | cytoplasm (0.81) | RAP1 FHL1 (0.69) |
Score: | | 0.65 | 0.36 | 0.66 | 0.692 |
P-value: | | 4.025E-12 (protein biosynthesis) | 4.923E-15 (structural constituent of ribosome) | 3.389E-16 (cytosolic ribosome (sensu Eukarya)) | 3.885E-21 (FHL1) |
RAP1(1) AND SWI5(1) => SimExpr(other) OR SimExpr(YOR369C) : 6 14
RAP1(1) AND SCB(1) => SimExpr(YOR369C) OR SimExpr(other) : 8 1
RAP1(1) AND SFF'(1) AND SCB(1) => SimExpr(YOR369C) : 8
RAP1(1) AND ALPHA1'(1) AND SCB(1) => SimExpr(YOR369C) : 5
RAP1(1) AND mRRPE(1) => SimExpr(other) OR SimExpr(YDL130W) : 2 5
EXPR: (0.098) mRRPE (P < 0.004) RAP1 (P < 0.375)
ORF | SYMBOL | P | F | C | TF |
|YMR013C| | SEC59 | protein-ER targeting, protein amino acid glycosylation -> cell organization and biogenesis, biosynthesis, protein modification, protein metabolism, transport | dolichol kinase activity -> dolichol kinase activity | membrane -> membrane | FHL1, NDD1, RAP1, RLM1, RME1 |
YOL121C | RPS19A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> cytosol, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome | AZF1, FHL1, GCR1, GCR2, HAL9, MET31, MOT3, PDR1, RAP1, ROX1, RPH1, SMP1, YAP6, ZAP1 |
YDL130W | RPP1B | protein biosynthesis, translational elongation -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytosol, ribosome | FHL1, GAL4, RAP1, RFX1 |
|YLR146C| | SPE4 | pantothenate biosynthesis, spermine biosynthesis -> biosynthesis, amine metabolism, coenzymes and prosthetic group metabolism, amino acid and derivative metabolism, secondary metabolism | spermine synthase activity -> spermine synthase activity | | |
YGL030W | RPL30 | protein biosynthesis, rRNA processing, mRNA splicing, regulation of translation -> cell organization and biogenesis, biosynthesis, transcription, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya), cytoplasm -> cytosol, cytoplasm, ribosome | FHL1, GAT3, RAP1, SFP1 |
YBR048W | RPS11B | protein biosynthesis, ribosomal small subunit assembly and maintenance, regulation of translational fidelity -> cell organization and biogenesis, biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> cytosol, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome | GAL4, HAP4, LEU3, MET31, MSN1 |
YLR249W | YEF3 | translational elongation -> biosynthesis, protein metabolism | translation elongation factor activity -> translation elongation factor activity | ribosome -> ribosome | INO2, INO4 |
Main: | | biosynthesis (1.00) | structural constituent of ribosome (0.57) | ribosome (0.83) | RAP1 FHL1 (0.67) |
Score: | | 1.00 | 0.29 | 0.67 | 0.533 |
P-value: | | 9.347E-04 (protein biosynthesis) | 8.551E-03 (structural constituent of ribosome) | 3.979E-03 (ribosome) | 1.076E-02 (FHL1) |
RAP1(1) => SimExpr(other) OR SimExpr(YPL131W) : 16 35
RAP1(1) AND SCB(1) => SimExpr(YPL131W) OR SimExpr(other) : 8 1
RAP1(1) AND ALPHA1(1) AND SCB(1) => SimExpr(YPL131W) : 5
RAP1(1) AND SFF'(1) AND SCB(1) => SimExpr(YPL131W) : 8
RAP1(1) AND ALPHA1'(1) AND SCB(1) => SimExpr(YPL131W) : 5
RAP1(1) => SimExpr(other) OR SimExpr(YBR181C) : 16 35
RAP1(1) AND SWI5(1) => SimExpr(other) OR SimExpr(YBR181C) : 6 14
RAP1(1) => SimExpr(other) OR SimExpr(YGL030W) : 15 36
RAP1(1) AND mRRPE(1) => SimExpr(other) OR SimExpr(YGL030W) : 1 6
RAP1(1) AND ALPHA1(1) AND SFF(1) => SimExpr(other) OR SimExpr(YLR061W) : 4 13
EXPR: (0.093) SFF (P < 0.000) RAP1 (P < 0.452) ALPHA1 (P < 0.000)
ORF | SYMBOL | P | F | C | TF |
YKR057W | RPS21A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | ABF1, FHL1 |
YKL006W | RPL14A | protein biosynthesis -> biosynthesis, protein metabolism | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, GRF10(Pho2), GTS1, RAP1 |
YPL131W | RPL5 | protein biosynthesis, ribosomal large subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, RAP1 |
YBL087C | RPL23A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, IXR1, MSS11, PDR1, RAP1, SMP1, SOK2 |
YLR061W | RPL22A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | BAS1, FHL1, HIR1, PDR1, RAP1, RCS1, RME1, ZAP1 |
YKL152C | GPM1 | gluconeogenesis, glycolysis -> alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism | phosphoglycerate mutase activity -> phosphoglycerate mutase activity | cytosol -> cytoplasm | GCR1, GCR2, HSF1, RAP1 |
|YMR231W| | PEP5 | nonselective vesicle docking, homotypic vacuole fusion (non-autophagic), Golgi to endosome transport, late endosome to vacuole transport -> cell organization and biogenesis, transport, vesicle-mediated transport | | vacuolar membrane (sensu Fungi) -> cytoplasm, vacuole | ARG81, DOT6, HAL9, HAP2, MCM1, YAP1 |
|YGR254W| | ENO1 | gluconeogenesis, glycolysis -> alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism | phosphopyruvate hydratase activity -> phosphopyruvate hydratase activity | phosphopyruvate hydratase complex, cytoplasm -> cytoplasm | FKH2, MSN4, PDR1, SWI5, YAP5 |
YKR092C | SRP40 | nucleocytoplasmic transport -> transport | chaperone activity -> chaperone activity | nucleolus -> nucleus | CUP9, MET4, RAP1 |
YER074W | RPS24A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, GAT3, PDR1, RAP1, RGM1, SMP1, YAP5 |
YJR139C | HOM6 | homoserine biosynthesis, methionine metabolism, threonine metabolism -> amine metabolism, sulfur metabolism, biosynthesis, amino acid and derivative metabolism, organic acid metabolism | homoserine dehydrogenase activity -> homoserine dehydrogenase activity | | HMS1, RAP1 |
YKL180W | RPL17A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya), cytoplasm -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, RAP1 |
|YBL093C| | ROX3 | transcription from Pol II promoter -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | RNA polymerase II transcription mediator activity -> RNA polymerase II transcription mediator activity | mediator complex, nucleus -> nucleus | FHL1, RAP1 |
YGR085C | RPL11B | protein biosynthesis, ribosomal large subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, MIG1 |
|YMR224C| | MRE11 | DNA repair, double-strand break repair via nonhomologous end-joining, meiotic DNA double-strand break formation, meiotic DNA double-strand break processing, double-strand break repair via break-induced replication -> DNA metabolism, cell proliferation, catabolism | endonuclease activity, 3'-5' exonuclease activity, protein binding -> endonuclease activity, 3'-5' exonuclease activity, protein binding | nucleus -> nucleus | RAP1 |
YHL033C | RPL8A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1 |
YLR249W | YEF3 | translational elongation -> biosynthesis, protein metabolism | translation elongation factor activity -> translation elongation factor activity | ribosome -> cytoplasm, ribonucleoprotein complex | INO2, INO4 |
Main: | | biosynthesis (0.76) | structural constituent of ribosome (0.56) | cytoplasm (0.81) | RAP1 (0.65) |
Score: | | 0.61 | 0.30 | 0.68 | 0.603 |
P-value: | | 1.244E-03 (protein biosynthesis) | 1.776E-05 (structural constituent of ribosome) | 5.236E-06 (cytosolic ribosome (sensu Eukarya)) | 2.239E-07 (FHL1) |
RAP1(1) => SimExpr(other) OR SimExpr(YOL121C) : 15 36
RAP1(1) AND SFF(1) => SimExpr(other) OR SimExpr(YOL121C) : 8 23
RAP1(1) AND mRRPE(1) => SimExpr(other) OR SimExpr(YOL121C) : 1 6
RAP1(1) => SimExpr(other) OR SimExpr(YKL006W) : 15 36
RAP1(1) AND SWI5(1) => SimExpr(other) OR SimExpr(YKL006W) : 6 14
RAP1(1) AND MCM1'(1) => SimExpr(other) OR SimExpr(YKL006W) : 5 16
RAP1(1) AND ALPHA1(1) => SimExpr(other) OR SimExpr(YKL006W) : 7 17
EXPR: (0.099) RAP1 (P < 0.739) ALPHA1 (P < 0.000)
ORF | SYMBOL | P | F | C | TF |
|YMR013C| | SEC59 | protein-ER targeting, protein amino acid glycosylation -> cell organization and biogenesis, biosynthesis, protein modification, protein metabolism, transport | dolichol kinase activity -> dolichol kinase activity | membrane -> membrane | FHL1, NDD1, RAP1, RLM1, RME1 |
|YBR117C| | TKL2 | pentose-phosphate shunt -> coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism | transketolase activity -> transketolase activity | | FHL1, RAP1 |
YKR057W | RPS21A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | ABF1, FHL1 |
YDL130W | RPP1B | protein biosynthesis, translational elongation -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, GAL4, RAP1, RFX1 |
YKL006W | RPL14A | protein biosynthesis -> biosynthesis, protein metabolism | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, GRF10(Pho2), GTS1, RAP1 |
YPL131W | RPL5 | protein biosynthesis, ribosomal large subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, RAP1 |
YBL087C | RPL23A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, IXR1, MSS11, PDR1, RAP1, SMP1, SOK2 |
YLR061W | RPL22A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | BAS1, FHL1, HIR1, PDR1, RAP1, RCS1, RME1, ZAP1 |
YKL152C | GPM1 | gluconeogenesis, glycolysis -> alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism | phosphoglycerate mutase activity -> phosphoglycerate mutase activity | cytosol -> cytoplasm | GCR1, GCR2, HSF1, RAP1 |
|YMR231W| | PEP5 | nonselective vesicle docking, homotypic vacuole fusion (non-autophagic), Golgi to endosome transport, late endosome to vacuole transport -> cell organization and biogenesis, transport, vesicle-mediated transport | | vacuolar membrane (sensu Fungi) -> cytoplasm, vacuole | ARG81, DOT6, HAL9, HAP2, MCM1, YAP1 |
|YER047C| | SAP1 | | | | MSS11 |
YIL018W | RPL2B | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, PDR1, RAP1, RGM1, SWI5, YAP5 |
|YGR254W| | ENO1 | gluconeogenesis, glycolysis -> alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism | phosphopyruvate hydratase activity -> phosphopyruvate hydratase activity | phosphopyruvate hydratase complex, cytoplasm -> cytoplasm | FKH2, MSN4, PDR1, SWI5, YAP5 |
YKR092C | SRP40 | nucleocytoplasmic transport -> transport | chaperone activity -> chaperone activity | nucleolus -> nucleus | CUP9, MET4, RAP1 |
YER074W | RPS24A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, GAT3, PDR1, RAP1, RGM1, SMP1, YAP5 |
YBR048W | RPS11B | protein biosynthesis, ribosomal small subunit assembly and maintenance, regulation of translational fidelity -> cell organization and biogenesis, biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | GAL4, HAP4, LEU3, MET31, MSN1 |
YJR139C | HOM6 | homoserine biosynthesis, methionine metabolism, threonine metabolism -> amine metabolism, sulfur metabolism, biosynthesis, amino acid and derivative metabolism, organic acid metabolism | homoserine dehydrogenase activity -> homoserine dehydrogenase activity | | HMS1, RAP1 |
YKL180W | RPL17A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya), cytoplasm -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, RAP1 |
|YBL093C| | ROX3 | transcription from Pol II promoter -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | RNA polymerase II transcription mediator activity -> RNA polymerase II transcription mediator activity | mediator complex, nucleus -> nucleus | FHL1, RAP1 |
YGR085C | RPL11B | protein biosynthesis, ribosomal large subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, MIG1 |
YOR213C | SAS5 | chromatin silencing at telomere -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription | acetyltransferase activity -> acetyltransferase activity | nuclear chromosome\, telomeric region, nuclear chromatin -> chromosome, nuclear chromosome | GRF10(Pho2), SUM1 |
|YMR224C| | MRE11 | DNA repair, double-strand break repair via nonhomologous end-joining, meiotic DNA double-strand break formation, meiotic DNA double-strand break processing, double-strand break repair via break-induced replication -> DNA metabolism, cell proliferation, catabolism | endonuclease activity, 3'-5' exonuclease activity, protein binding -> endonuclease activity, 3'-5' exonuclease activity, protein binding | nucleus -> nucleus | RAP1 |
YHL033C | RPL8A | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1 |
YLR249W | YEF3 | translational elongation -> biosynthesis, protein metabolism | translation elongation factor activity -> translation elongation factor activity | ribosome -> cytoplasm, ribonucleoprotein complex | INO2, INO4 |
Main: | | biosynthesis (0.74) | structural constituent of ribosome (0.55) | cytoplasm (0.76) | RAP1 (0.62) |
Score: | | 0.60 | 0.29 | 0.59 | 0.536 |
P-value: | | 3.678E-05 (protein biosynthesis) | 7.440E-07 (structural constituent of ribosome) | 1.053E-07 (cytosolic ribosome (sensu Eukarya)) | 1.895E-10 (FHL1) |
RAP1(1) AND SWI5(1) AND MCM1'(1) => SimExpr(YKL006W) OR SimExpr(other) : 6 1
RAP1(1) AND ALPHA1(1) AND SWI5(1) => SimExpr(other) OR SimExpr(YKL006W) : 2 6
RAP1(1) AND SFF(1) AND SWI5(1) => SimExpr(YLR441C) OR SimExpr(other) : 10 4
RAP1(1) AND mRRPE(1) => SimExpr(other) OR SimExpr(YBR048W) : 1 6
mRRPE(1) AND PAC(1) => SimExpr(YLR249W) OR SimExpr(other) : 27 2
mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YLR249W) OR SimExpr(other) : 10 1
mRRPE(1) AND SWI5(1) AND PAC(1) => SimExpr(YLR249W) OR SimExpr(other) : 6 1
EXPR: (0.085) mRRPE (P < 0.003) SWI5 (P < 0.000) PAC (P < 0.022)
ORF | SYMBOL | P | F | C | TF |
|YGL016W| | KAP122 | protein-nucleus import, response to drug -> response to abiotic stimulus, protein metabolism, transport | protein carrier activity -> protein carrier activity | cytoplasm, nuclear pore -> cytoplasm, nucleus, integral to membrane, endomembrane system | MSN2 |
YDR399W | HPT1 | purine nucleotide biosynthesis -> biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | hypoxanthine phosphoribosyltransferase activity -> hypoxanthine phosphoribosyltransferase activity | | |
YMR229C | RRP5 | rRNA processing, processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | RNA binding, snoRNA binding -> RNA binding, snoRNA binding | nucleolus, nucleolus organizer complex -> nucleus | FHL1, RAP1 |
YJR002W | MPP10 | rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription | | small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex, nucleolus, nucleus -> nucleus, ribonucleoprotein complex | |
YOR310C | NOP58 | rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription | | small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex | ABF1, SWI6 |
YHR089C | GAR1 | rRNA modification, 35S primary transcript processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription | RNA binding -> RNA binding | nucleolus, small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex | CBF1, FZF1 |
YLR249W | YEF3 | translational elongation -> biosynthesis, protein metabolism | translation elongation factor activity -> translation elongation factor activity | ribosome -> cytoplasm, ribonucleoprotein complex | INO2, INO4 |
Main: | | nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.71) | RNA binding (0.40) | nucleus (0.83) | ABF1 (0.20) |
Score: | | 0.57 | 0.10 | 0.93 | 0.000 |
P-value: | | 3.512E-05 (rRNA modification) | 4.289E-01 (nucleic acid binding) | 2.184E-05 (small nucleolar ribonucleoprotein complex) | 2.685E-01 (MSN2) |
RAP1(1) AND SCB(1) => SimExpr(YLR249W) OR SimExpr(other) : 8 1
RAP1(1) AND mRRPE(1) => SimExpr(other) OR SimExpr(YLR249W) : 1 6
RAP1(1) AND ALPHA1(1) AND SFF(1) AND SWI5(1) => SimExpr(YLR249W) OR SimExpr(other) : 5 1
EXPR: (0.088) SFF (P < 0.000) SWI5 (P < 0.000) RAP1 (P < 0.106) ALPHA1 (P < 0.000)
ORF | SYMBOL | P | F | C | TF |
YKL006W | RPL14A | protein biosynthesis -> protein biosynthesis | RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, GAT3, GRF10(Pho2), GTS1, RAP1 |
YBL087C | RPL23A | protein biosynthesis -> protein biosynthesis | structural constituent of ribosome -> structural constituent of ribosome | cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex | FHL1, IXR1, MSS11, PDR1, RAP1, SMP1, SOK2 |
YKR092C | SRP40 | nucleocytoplasmic transport -> nucleocytoplasmic transport | chaperone activity -> chaperone activity | nucleolus -> nucleus | CUP9, MET4, RAP1 |
YER074W | RPS24A | protein biosynthesis -> protein biosynthesis | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, GAT3, PDR1, RAP1, RGM1, SMP1, YAP5 |
|YMR224C| | MRE11 | DNA repair, double-strand break repair via nonhomologous end-joining, meiotic DNA double-strand break formation, meiotic DNA double-strand break processing, double-strand break repair via break-induced replication -> mitotic recombination, M phase, DNA catabolism, DNA recombination, DNA repair | endonuclease activity, 3'-5' exonuclease activity, protein binding -> endonuclease activity, 3'-5' exonuclease activity, protein binding | nucleus -> nucleus | RAP1 |
YLR249W | YEF3 | translational elongation -> protein biosynthesis | translation elongation factor activity -> translation elongation factor activity | ribosome -> cytoplasm, ribonucleoprotein complex | INO2, INO4 |
Main: | | protein biosynthesis (0.67) | structural constituent of ribosome (0.50) | cytoplasm (0.67) | RAP1 (0.83) |
Score: | | 0.40 | 0.20 | 0.47 | 0.667 |
P-value: | | 5.607E-02 (protein biosynthesis) | 5.977E-02 (structural constituent of ribosome) | 2.140E-02 (ribosome) | 5.176E-04 (RAP1) |
ALPHA1(1) AND mRRPE(1) AND PAC(1) => SimExpr(YLR249W) : 7
EXPR: (0.092) mRRPE (P < 0.012) PAC (P < 0.045) ALPHA1 (P < 0.000)
ORF | SYMBOL | P | F | C | TF |
YJL033W | HCA4 | 35S primary transcript processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | ATP dependent RNA helicase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides | nucleolus -> nucleus | HIR2, USV1 |
YMR229C | RRP5 | rRNA processing, processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | RNA binding, snoRNA binding -> RNA binding | nucleolus, nucleolus organizer complex -> nucleus | FHL1, RAP1 |
YJR002W | MPP10 | rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription | | small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex, nucleolus, nucleus -> nucleus, ribonucleoprotein complex | |
YHR128W | FUR1 | pyrimidine salvage -> biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | uracil phosphoribosyltransferase activity -> transferase activity\, transferring glycosyl groups | | CIN5 |
YOR095C | RKI1 | pentose-phosphate shunt -> coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism | ribose-5-phosphate isomerase activity -> intramolecular isomerase activity | | FHL1, FKH2, RAP1 |
YMR239C | RNT1 | 35S primary transcript processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | ribonuclease III activity -> hydrolase activity\, acting on ester bonds, RNA binding | nucleolus -> nucleus | |
YLR249W | YEF3 | translational elongation -> biosynthesis, protein metabolism | translation elongation factor activity -> translation factor activity\, nucleic acid binding | ribosome -> cytoplasm, ribonucleoprotein complex | INO2, INO4 |
Main: | | nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.71) | RNA binding (0.50) | nucleus (0.80) | RAP1 FHL1 (0.40) |
Score: | | 0.52 | 0.20 | 0.70 | 0.100 |
P-value: | | 2.713E-04 (rRNA processing) | 7.534E-02 (RNA binding) | 1.842E-04 (nucleolus) | 5.170E-01 (USV1) |
RAP1(1) AND ALPHA1(1) AND SCB(1) => SimExpr(YLR249W) : 5
RAP1(1) AND SFF'(1) AND SCB(1) => SimExpr(YLR249W) : 8
RAP1(1) AND mRRPE(1) => SimExpr(other) OR SimExpr(YLR146C) : 2 5
RAP1(1) AND SCB(1) => SimExpr(YBL087C) OR SimExpr(other) : 8 1
RAP1(1) AND ALPHA1(1) AND SCB(1) => SimExpr(YBL087C) : 5
RAP1(1) AND SFF'(1) AND SCB(1) => SimExpr(YBL087C) : 8
ndt80(MSE)(1) AND SWI5(1) => SimExpr(YPR122W) OR SimExpr(other) : 7 2
EXPR: (0.108) ndt80(MSE) (P < 0.061) SWI5 (P < 0.000)
ORF | SYMBOL | P | F | C | TF |
YPR122W | AXL1 | axial budding, bud site selection, conjugation with cellular fusion, peptide pheromone maturation -> asexual reproduction, conjugation, protein metabolism, cell proliferation, cell organization and biogenesis, sexual reproduction | metalloendopeptidase activity -> metalloendopeptidase activity | integral to membrane, bud neck, shmoo tip -> integral to membrane, site of polarized growth (sensu Fungi) | CIN5 |
YER155C | BEM2 | cell wall organization and biogenesis, bud growth, small GTPase mediated signal transduction, establishment of cell polarity (sensu Saccharomyces), actin cytoskeleton organization and biogenesis, microtubule cytoskeleton organization and biogenesis -> asexual reproduction, signal transduction, cell organization and biogenesis, organelle organization and biogenesis | signal transducer activity -> signal transducer activity | intracellular -> intracellular | |
YGL116W | CDC20 | mitotic spindle elongation, ubiquitin-dependent protein catabolism, mitotic metaphase/anaphase transition, mitotic chromosome segregation, cyclin catabolism -> cell organization and biogenesis, catabolism, cell proliferation, cell cycle, protein metabolism | enzyme activator activity -> enzyme activator activity | anaphase-promoting complex -> intracellular | DIG1, FKH2, INO2, INO4, IXR1, MCM1, NDD1 |
YFR023W | PES4 | DNA dependent DNA replication -> cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | | | DIG1, FKH1, FKH2, GLN3, HAP3, MCM1, MSN2, RIM101, RLM1, RTG3, STE12, SUM1, THI2, YAP1 |
YMR001C | CDC5 | DNA dependent DNA replication, protein amino acid phosphorylation -> phosphorus metabolism, cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism | protein serine/threonine kinase activity -> protein serine/threonine kinase activity | nucleus, spindle pole, bud neck -> intracellular, site of polarized growth (sensu Fungi) | NDD1, REB1, SWI6 |
|YHL043W| | ECM34 | cell wall organization and biogenesis -> cell organization and biogenesis | | | |
YMR280C | CAT8 | gluconeogenesis, positive regulation of transcription from Pol II promoter -> alcohol metabolism, monosaccharide metabolism, carbohydrate metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, biosynthesis, energy pathways | specific RNA polymerase II transcription factor activity -> specific RNA polymerase II transcription factor activity | nucleus -> intracellular | ABF1, REB1 |
YKL104C | GFA1 | cell wall chitin biosynthesis -> cell organization and biogenesis, biosynthesis, polysaccharide metabolism, carbohydrate metabolism | glucosamine-fructose-6-phosphate aminotransferase (isomerizing) activity -> glucosamine-fructose-6-phosphate aminotransferase (isomerizing) activity | | REB1 |
|YJR007W| | SUI2 | translational initiation -> biosynthesis, protein metabolism | translation initiation factor activity -> translation initiation factor activity | ribosome, cytoplasm -> intracellular | GLN3, HAP3, HIR1, RCS1 |
Main: | | cell organization and biogenesis (0.56) | metalloendopeptidase activity (0.14) | intracellular (0.83) | REB1 (0.43) |
Score: | | 0.64 | 0.00 | 0.73 | 0.286 |
P-value: | | 1.445E-01 (external encapsulating structure organization and biogenesis) | 1.561E+00 (transferase activity) | 1.713E-01 (bud neck) | 1.744E-01 (REB1) |
ALPHA1(1) AND ndt80(MSE)(1) AND SWI5(1) => SimExpr(YPR122W) : 5
EXPR: (0.090) ndt80(MSE) (P < 0.025) SWI5 (P < 0.000) ALPHA1 (P < 0.000)
ORF | SYMBOL | P | F | C | TF |
YPR122W | AXL1 | axial budding, bud site selection, conjugation with cellular fusion, peptide pheromone maturation -> asexual reproduction, conjugation, protein metabolism, cell proliferation, cell organization and biogenesis, sexual reproduction | metalloendopeptidase activity -> metalloendopeptidase activity | integral to membrane, bud neck, shmoo tip -> integral to membrane, site of polarized growth (sensu Fungi) | CIN5 |
YGL116W | CDC20 | mitotic spindle elongation, ubiquitin-dependent protein catabolism, mitotic metaphase/anaphase transition, mitotic chromosome segregation, cyclin catabolism -> cell organization and biogenesis, catabolism, cell proliferation, cell cycle, protein metabolism | enzyme activator activity -> enzyme activator activity | anaphase-promoting complex -> nucleus, ubiquitin ligase complex | DIG1, FKH2, INO2, INO4, IXR1, MCM1, NDD1 |
YFR023W | PES4 | DNA dependent DNA replication -> cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | | | DIG1, FKH1, FKH2, GLN3, HAP3, MCM1, MSN2, RIM101, RLM1, RTG3, STE12, SUM1, THI2, YAP1 |
YMR001C | CDC5 | DNA dependent DNA replication, protein amino acid phosphorylation -> phosphorus metabolism, cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism | protein serine/threonine kinase activity -> protein serine/threonine kinase activity | nucleus, spindle pole, bud neck -> nucleus, cytoplasm, site of polarized growth (sensu Fungi) | NDD1, REB1, SWI6 |
YMR280C | CAT8 | gluconeogenesis, positive regulation of transcription from Pol II promoter -> alcohol metabolism, monosaccharide metabolism, carbohydrate metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, biosynthesis, energy pathways | specific RNA polymerase II transcription factor activity -> specific RNA polymerase II transcription factor activity | nucleus -> nucleus | ABF1, REB1 |
Main: | | cell proliferation (0.80) | metalloendopeptidase activity (0.25) | nucleus (0.75) | FKH2 NDD1 MCM1 REB1 DIG1 (0.40) |
Score: | | 0.80 | 0.00 | 0.67 | 0.300 |
P-value: | | 2.055E-02 (cell proliferation) | 2.543E+00 (enzyme activity) | 4.566E-02 (bud neck) | 7.290E-02 (DIG1) |
ALPHA1(1) AND ALPHA2(1) AND ALPHA1'(1) AND mRRPE(1) => SimExpr(YER131W) OR SimExpr(other) : 5 2
EXPR: (0.112) ALPHA2 (P < 0.006) ALPHA1' (P < 0.009) mRRPE (P < 0.187) ALPHA1 (P < 0.008)
ORF | SYMBOL | P | F | C | TF |
YDR023W | SES1 | amino acid activation -> biosynthesis, protein metabolism | serine-tRNA ligase activity -> serine-tRNA ligase activity | cytoplasm -> cytoplasm | GRF10(Pho2), MOT3 |
YJL033W | HCA4 | 35S primary transcript processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | ATP dependent RNA helicase activity -> ATP dependent RNA helicase activity | nucleolus -> nucleus | HIR2, USV1 |
|YHR128W| | FUR1 | pyrimidine salvage -> biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | uracil phosphoribosyltransferase activity -> uracil phosphoribosyltransferase activity | | CIN5 |
YNL111C | CYB5 | sterol biosynthesis -> alcohol metabolism, biosynthesis, lipid metabolism | electron transporter activity -> electron transporter activity | microsome -> membrane fraction | ABF1, GCR2, GTS1, NRG1, REB1, ROX1 |
YER131W | RPS26B | protein biosynthesis -> biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | FHL1, RAP1 |
YBR048W | RPS11B | protein biosynthesis, ribosomal small subunit assembly and maintenance, regulation of translational fidelity -> cell organization and biogenesis, biosynthesis, protein metabolism | structural constituent of ribosome -> structural constituent of ribosome | cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex | GAL4, HAP4, LEU3, MET31, MSN1 |
|YBR294W| | SUL1 | sulfate transport -> transport | sulfate transporter activity -> sulfate transporter activity | plasma membrane -> plasma membrane | STB1 |
Main: | | biosynthesis (0.71) | structural constituent of ribosome (0.29) | cytoplasm (0.50) | GCR2 (0.14) |
Score: | | 0.57 | 0.05 | 0.20 | 0.000 |
P-value: | | 3.036E-01 (biosynthesis) | 6.853E-01 (structural constituent of ribosome) | 1.945E-01 (cytosolic small ribosomal subunit (sensu Eukarya)) | 6.785E-01 (MSN1) |
LYS14(1) AND ATRepeat(1) => SimExpr(YDR226W) OR SimExpr(other) : 5 1
mRRPE(1) AND PAC(1) => SimExpr(YMR239C) OR SimExpr(other) : 26 3
mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YMR239C) : 11
ALPHA1'(1) AND MCB(1) AND SCB(1) => SimExpr(other) OR SimExpr(YGL225W) : 2 5
ALPHA1(1) AND mRRPE(1) AND PAC(1) => SimExpr(YJL033W) OR SimExpr(other) : 6 1
ALPHA1'(1) AND SFF(1) AND RPN4(1) => SimExpr(other) OR SimExpr(YOR362C) : 3 9
EXPR: (0.114) ALPHA1' (P < 0.000) SFF (P < 0.000) RPN4 (P < 0.140)
ORF | SYMBOL | P | F | C | TF |
YDR394W | RPT3 | ubiquitin-dependent protein catabolism -> macromolecule catabolism, protein metabolism | ATPase activity, endopeptidase activity -> purine nucleotide binding, peptidase activity, hydrolase activity\, acting on acid anhydrides | proteasome regulatory particle (sensu Eukarya), proteasome regulatory particle\, base subcomplex (sensu Eukarya) -> cytosol, endoplasmic reticulum, nucleus | RTG1 |
YDL126C | CDC48 | ubiquitin-dependent protein catabolism, nonselective vesicle fusion, cell cycle, apoptosis, protein transport, ER-associated protein catabolism -> secretory pathway, cell cycle, programmed cell death, protein transport, macromolecule catabolism, vesicle-mediated transport, protein metabolism | ATPase activity -> purine nucleotide binding, hydrolase activity\, acting on acid anhydrides | nucleus, microsome, endoplasmic reticulum, cytosol -> nucleus, vesicular fraction, endoplasmic reticulum, cytosol | DAL82, MAL33, SWI4 |
|YER109C| | FLO8 | pseudohyphal growth, invasive growth -> cellular morphogenesis | specific RNA polymerase II transcription factor activity -> specific RNA polymerase II transcription factor activity | nucleus, cytoplasm -> nucleus, cytoplasm | |
|YGR184C| | UBR1 | protein polyubiquitination, protein monoubiquitination -> macromolecule catabolism, protein modification, protein metabolism | ubiquitin-protein ligase activity -> ligase activity\, forming carbon-nitrogen bonds | proteasome complex (sensu Eukarya) -> cytosol, endoplasmic reticulum, nucleus | HMS1, REB1, RIM101 |
YER012W | PRE1 | ubiquitin-dependent protein catabolism, response to stress, sporulation (sensu Saccharomyces) -> macromolecule catabolism, response to stress, sporulation (sensu Fungi), protein metabolism | endopeptidase activity -> peptidase activity | proteasome core complex (sensu Eukarya), nucleus -> cytosol, nucleus, endoplasmic reticulum | |
YOR362C | PRE10 | ubiquitin-dependent protein catabolism -> macromolecule catabolism, protein metabolism | endopeptidase activity -> peptidase activity | proteasome core complex (sensu Eukarya) -> cytosol, endoplasmic reticulum, nucleus | |
|YGR124W| | ASN2 | asparagine biosynthesis -> amine biosynthesis, amine metabolism, amino acid and derivative metabolism, carboxylic acid metabolism | asparagine synthase (glutamine-hydrolyzing) activity -> ligase activity\, forming carbon-nitrogen bonds | | ASH1, ROX1 |
YNL012W | SPO1 | meiosis -> cell cycle | phospholipase activity -> hydrolase activity\, acting on ester bonds | nucleus -> nucleus | ARO80, SRD1 |
YML092C | PRE8 | ubiquitin-dependent protein catabolism -> macromolecule catabolism, protein metabolism | endopeptidase activity -> peptidase activity | proteasome core complex (sensu Eukarya) -> cytosol, endoplasmic reticulum, nucleus | |
YGL201C | MCM6 | DNA unwinding, DNA replication initiation -> cell cycle, DNA metabolism | chromatin binding, ATP dependent DNA helicase activity -> DNA binding, adenyl nucleotide binding, hydrolase activity\, acting on acid anhydrides | cytoplasm, nucleus, pre-replicative complex -> cytoplasm, nucleus, nucleoplasm | MCM1 |
YOL038W | PRE6 | ubiquitin-dependent protein catabolism -> macromolecule catabolism, protein metabolism | endopeptidase activity -> peptidase activity | proteasome core complex (sensu Eukarya) -> cytosol, endoplasmic reticulum, nucleus | |
YMR100W | MUB1 | regulation of budding -> budding | | | |
Main: | | macromolecule catabolism (0.58) | peptidase activity (0.45) | nucleus (1.00) | SWI4 (0.17) |
Score: | | 0.36 | 0.25 | 1.00 | 0.000 |
P-value: | | 6.617E-07 (ubiquitin-dependent protein catabolism) | 6.074E-06 (endopeptidase activity) | 2.116E-08 (proteasome complex (sensu Eukarya)) | 7.267E-01 (MAL33) |
ALPHA1(1) AND ALPHA1'(1) AND MCB(1) => SimExpr(YDR097C) OR SimExpr(other) : 5 2
ABF1(1) AND SFF(1) AND mRRPE(1) => SimExpr(YLR293C) OR SimExpr(other) : 8 3
EXPR: (0.107) ABF1 (P < 0.000) SFF (P < 0.000) mRRPE (P < 0.035)
ORF | SYMBOL | P | F | C | TF |
|YAR019C| | CDC15 | cytokinesis, regulation of exit from mitosis, protein amino acid phosphorylation -> phosphorus metabolism, cell proliferation, mitotic cell cycle, protein metabolism | protein kinase activity -> transferase activity\, transferring phosphorus-containing groups | spindle pole body -> cytoplasm | PHO4 |
|YAL016W| | TPD3 | protein biosynthesis, actin filament organization, mitotic spindle checkpoint, bud growth, protein amino acid dephosphorylation -> biosynthesis, cell organization and biogenesis, asexual reproduction, phosphorus metabolism, cell proliferation, cell cycle, protein metabolism | protein phosphatase type 2A activity -> hydrolase activity\, acting on ester bonds | protein phosphatase type 2A complex, bud neck, nucleus, cytoplasm, shmoo tip, bud tip, spindle pole body -> protein phosphatase type 2A complex, nucleus, site of polarized growth (sensu Fungi), site of polarized growth (sensu Saccharomyces), cytoplasm, microtubule organizing center | ABF1 |
YER110C | KAP123 | protein-nucleus import -> protein metabolism, transport | protein carrier activity -> protein carrier activity | cytoplasm, nuclear pore, nucleus -> cytoplasm, nucleus, integral to membrane, endomembrane system | |
YNL292W | PUS4 | tRNA modification -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | pseudouridylate synthase activity -> carbon-oxygen lyase activity | mitochondrion, nucleus -> cytoplasm, nucleus | RCS1 |
YDR172W | SUP35 | translational termination -> biosynthesis, protein metabolism | translation release factor activity -> translation factor activity\, nucleic acid binding | cytosol -> cytoplasm | ABF1, ZMS1 |
YNL111C | CYB5 | sterol biosynthesis -> alcohol metabolism, biosynthesis, lipid metabolism | electron transporter activity -> electron transporter activity | microsome -> membrane fraction | ABF1, GCR2, GTS1, NRG1, REB1, ROX1 |
YGR282C | BGL2 | cell wall organization and biogenesis -> cell organization and biogenesis | glucan 1\,3-beta-glucosidase activity -> hydrolase activity\, acting on glycosyl bonds | cell wall -> cell wall | ABF1, CIN5, SMP1 |
YDR385W | EFT2 | translational elongation -> biosynthesis, protein metabolism | translation elongation factor activity -> translation factor activity\, nucleic acid binding | ribosome -> cytoplasm, ribonucleoprotein complex | ABF1, FHL1, INO4 |
YLR293C | GSP1 | nucleocytoplasmic transport, nuclear organization and biogenesis, rRNA processing -> transport, cell organization and biogenesis, RNA metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | RAN small monomeric GTPase activity -> purine nucleotide binding, hydrolase activity\, acting on acid anhydrides | cytoplasm, nucleus -> cytoplasm, nucleus | ABF1 |
YMR308C | PSE1 | mRNA-nucleus export -> transport, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | protein carrier activity -> protein carrier activity | nucleus, cytoplasm -> nucleus, cytoplasm | SWI4 |
|YJL159W| | HSP150 | cell wall organization and biogenesis -> cell organization and biogenesis | structural constituent of cell wall -> structural constituent of cell wall | cell wall -> cell wall | ACE2, HIR2, MCM1, RLM1, SWI5 |
Main: | | protein metabolism (0.45) | protein carrier activity (0.18) | cytoplasm (0.73) | ABF1 (0.60) |
Score: | | 0.44 | 0.04 | 0.53 | 0.333 |
P-value: | | 7.051E-02 (nucleocytoplasmic transport) | 1.280E-02 (protein carrier activity) | 1.747E-01 (spindle pole body) | 1.106E-03 (ABF1) |
ABF1(1) AND PAC(1) => SimExpr(YJL050W) : 5
EXPR: (0.078) ABF1 (P < 0.000) PAC (P < 0.007)
ORF | SYMBOL | P | F | C | TF |
YLR197W | SIK1 | rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> RNA processing, ribosome biogenesis and assembly, rRNA metabolism, transcription\, DNA-dependent | | small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex, nucleus, nucleolus -> nucleus, ribonucleoprotein complex | DAL81, HAL9 |
YER110C | KAP123 | protein-nucleus import -> intracellular protein transport, nucleocytoplasmic transport, protein metabolism | protein carrier activity -> protein carrier activity | cytoplasm, nuclear pore, nucleus -> cytoplasm, nucleus, integral to membrane, endomembrane system | |
YNL112W | DBP2 | | RNA helicase activity -> RNA helicase activity | bud neck -> site of polarized growth (sensu Fungi) | |
YNL292W | PUS4 | tRNA modification -> RNA processing, tRNA metabolism | pseudouridylate synthase activity -> pseudouridylate synthase activity | mitochondrion, nucleus -> cytoplasm, nucleus | RCS1 |
YJL050W | MTR4 | 35S primary transcript processing -> ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent | ATP dependent RNA helicase activity -> RNA helicase activity, ATP dependent helicase activity, RNA dependent ATPase activity | nucleolus -> nucleus | |
Main: | | RNA processing (0.75) | RNA helicase activity (0.50) | nucleus (0.80) | RCS1 (0.50) |
Score: | | 0.50 | 0.17 | 0.60 | 0.000 |
P-value: | | 8.295E-03 (RNA modification) | 1.022E-02 (RNA helicase activity) | 6.316E-02 (nucleolus) | 1.521E-01 (HAL9) |
SFF(1) AND RPN4(1) => SimExpr(other) OR SimExpr(YNL012W) : 5 12
EXPR: (0.117) SFF (P < 0.000) RPN4 (P < 0.173)
ORF | SYMBOL | P | F | C | TF |
YDR394W | RPT3 | ubiquitin-dependent protein catabolism -> catabolism, protein metabolism | ATPase activity, endopeptidase activity -> purine nucleotide binding, peptidase activity, hydrolase activity\, acting on acid anhydrides | proteasome regulatory particle (sensu Eukarya), proteasome regulatory particle\, base subcomplex (sensu Eukarya) -> cytoplasm, nucleus | RTG1 |
YDL126C | CDC48 | ubiquitin-dependent protein catabolism, nonselective vesicle fusion, cell cycle, apoptosis, protein transport, ER-associated protein catabolism -> cell proliferation, cell death, macromolecule catabolism, transport, protein metabolism | ATPase activity -> purine nucleotide binding, hydrolase activity\, acting on acid anhydrides | nucleus, microsome, endoplasmic reticulum, cytosol -> nucleus, membrane fraction, cytoplasm | DAL82, MAL33, SWI4 |
|YER109C| | FLO8 | pseudohyphal growth, invasive growth -> cell organization and biogenesis | specific RNA polymerase II transcription factor activity -> specific RNA polymerase II transcription factor activity | nucleus, cytoplasm -> nucleus, cytoplasm | |
|YGR184C| | UBR1 | protein polyubiquitination, protein monoubiquitination -> catabolism, protein metabolism | ubiquitin-protein ligase activity -> ligase activity\, forming carbon-nitrogen bonds | proteasome complex (sensu Eukarya) -> cytoplasm, nucleus | HMS1, REB1, RIM101 |
YER012W | PRE1 | ubiquitin-dependent protein catabolism, response to stress, sporulation (sensu Saccharomyces) -> catabolism, response to stress, sporulation, protein metabolism | endopeptidase activity -> peptidase activity | proteasome core complex (sensu Eukarya), nucleus -> nucleus, cytoplasm | |
YOR362C | PRE10 | ubiquitin-dependent protein catabolism -> catabolism, protein metabolism | endopeptidase activity -> peptidase activity | proteasome core complex (sensu Eukarya) -> cytoplasm, nucleus | |
YIL075C | RPN2 | ubiquitin-dependent protein catabolism -> catabolism, protein metabolism | receptor activity, endopeptidase activity -> receptor activity, peptidase activity | proteasome regulatory particle (sensu Eukarya) -> cytoplasm, nucleus | MSS11, REB1, SFL1 |
|YGR124W| | ASN2 | asparagine biosynthesis -> amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis | asparagine synthase (glutamine-hydrolyzing) activity -> ligase activity\, forming carbon-nitrogen bonds | | ASH1, ROX1 |
YFR050C | PRE4 | ubiquitin-dependent protein catabolism -> catabolism, protein metabolism | endopeptidase activity -> peptidase activity | proteasome core complex (sensu Eukarya) -> cytoplasm, nucleus | MTH1, REB1 |
|YNL251C| | NRD1 | nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | RNA binding -> RNA binding | nucleus -> nucleus | ABF1, MAC1 |
|YKL135C| | APL2 | vesicle-mediated transport -> transport | clathrin binding -> clathrin binding | AP-1 adaptor complex -> cytoplasmic vesicle, cytoplasm | ABF1, DOT6 |
YNL012W | SPO1 | meiosis -> cell proliferation | phospholipase activity -> hydrolase activity\, acting on ester bonds | nucleus -> nucleus | ARO80, SRD1 |
YGR286C | BIO2 | biotin biosynthesis -> biosynthesis, coenzymes and prosthetic group metabolism, vitamin metabolism, heterocycle metabolism, organic acid metabolism, sulfur metabolism | biotin synthase activity -> transferase activity\, transferring sulfur-containing groups | | |
YML092C | PRE8 | ubiquitin-dependent protein catabolism -> catabolism, protein metabolism | endopeptidase activity -> peptidase activity | proteasome core complex (sensu Eukarya) -> cytoplasm, nucleus | |
YGL201C | MCM6 | DNA unwinding, DNA replication initiation -> cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism | chromatin binding, ATP dependent DNA helicase activity -> DNA binding, adenyl nucleotide binding, hydrolase activity\, acting on acid anhydrides | cytoplasm, nucleus, pre-replicative complex -> cytoplasm, nucleus | MCM1 |
YOL038W | PRE6 | ubiquitin-dependent protein catabolism -> catabolism, protein metabolism | endopeptidase activity -> peptidase activity | proteasome core complex (sensu Eukarya) -> cytoplasm, nucleus | |
YMR100W | MUB1 | regulation of budding -> asexual reproduction | | | |
Main: | | protein metabolism (0.53) | peptidase activity (0.44) | nucleus (0.93) | REB1 (0.30) |
Score: | | 0.31 | 0.21 | 0.98 | 0.089 |
P-value: | | 2.455E-08 (ubiquitin-dependent protein catabolism) | 1.712E-08 (endopeptidase activity) | 3.549E-11 (proteasome complex (sensu Eukarya)) | 8.044E-01 (REB1) |
SWI5(1) AND PAC(1) => SimExpr(YHR089C) OR SimExpr(other) : 8 3
mRRPE(1) AND PAC(1) => SimExpr(YHR089C) OR SimExpr(other) : 28 1
mRRPE(1) AND PAC(1) => SimExpr(YPL043W) OR SimExpr(other) : 28 1
mRRPE(1) AND PAC(1) AND MCM1'(1) => SimExpr(YPL043W) : 6
AVERAGE SCORES:
P
SCORE: 0.621 (Part of genes covered by "Main": 0.729) (No. rules=52/52)
P-VALUE: 0.635
F
SCORE: 0.230 (Part of genes covered by "Main": 0.457) (No. rules=52/52)
P-VALUE: 0.538
C
SCORE: 0.692 (Part of genes covered by "Main": 0.795) (No. rules=52/52)
P-VALUE: 0.596
TF
SCORE: 0.409 (Part of genes covered by "Main": 0.553) (No. rules=50/52)
P-VALUE: 0.520
EXPRESSION: 0.462 (52)