Binding site rules

mRRPE(1) AND PAC(1) => SimExpr(YGR280C) OR SimExpr(other) : 63 13

EXPR: (0.157) mRRPE (P < 0.000) PAC (P < 0.000)

mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YGR280C) OR SimExpr(other) : 16 4

EXPR: (0.148) mRRPE (P < 0.000) PAC (P < 0.000) SCB (P < 0.000)

mRRPE(1) AND PAC(1) AND MCM1'(1) => SimExpr(YGR280C) OR SimExpr(other) : 10 4

EXPR: (0.162) mRRPE (P < 0.000) PAC (P < 0.021) MCM1' (P < 0.000)

mRRPE(1) AND SWI5(1) AND PAC(1) => SimExpr(YGR280C) OR SimExpr(other) : 11 5

EXPR: (0.178) mRRPE (P < 0.006) SWI5 (P < 0.000) PAC (P < 0.095)

ORF SYMBOL P F C TF
YOR310C NOP58 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex ABF1, SWI6
YGR245C SDA1 actin cytoskeleton organization and biogenesis, start control point of mitotic cell cycle ->
cell organization and biogenesis, cell proliferation nucleus ->
nucleus
YDR399W HPT1 purine nucleotide biosynthesis ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism hypoxanthine phosphoribosyltransferase activity ->
transferase activity\, transferring glycosyl groups
|YPR183W| DPM1 N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
lipid biosynthesis, biosynthesis, membrane lipid metabolism, protein metabolism, lipoprotein metabolism transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
cytoplasm, endomembrane system SWI5
YMR229C RRP5 rRNA processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding, snoRNA binding ->
RNA binding nucleolus, nucleolus organizer complex ->
nucleus FHL1, RAP1
YLR249W YEF3 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
translation factor activity\, nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex INO2, INO4
YJR002W MPP10 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex, nucleolus, nucleus ->
nucleus, ribonucleoprotein complex
YFR001W LOC1 ribosomal large subunit biogenesis ->
cell organization and biogenesis mRNA binding ->
RNA binding nucleus ->
nucleus ARG80, GAL4, GTS1, HAP4, HIR1, LEU3, MSN2, MSN4, RCS1, RLM1, SWI4
|YML125C| NO SYMBOL MAL13, MSN4, NDD1, RME1, SWI5
YPR010C RPA135 transcription from Pol I promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DNA-directed RNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups DNA-directed RNA polymerase I complex ->
nucleus ROX1, SIG1
|YDR279W| RNH202 GCR2, MBP1, RIM101, RLM1, SWI6, THI2
YNR024W NO SYMBOL
|YMR259C| NO SYMBOL ARG80, GCR2, GTS1, HIR1, SRD1
|YGL016W| KAP122 protein-nucleus import, response to drug ->
response to abiotic stimulus, protein metabolism, transport protein carrier activity ->
protein carrier activity cytoplasm, nuclear pore ->
cytoplasm, nucleus, integral to membrane, endomembrane system MSN2
YJL109C UTP10 processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding nucleolus ->
nucleus
Main: cell organization and biogenesis (0.58) RNA binding (0.44) nucleus (0.82) GCR2 ARG80 RLM1 MSN2 SWI5 MSN4 SWI6 HIR1 GTS1 (0.20)
Score: 0.56 0.19 0.76 0.156
P-value: 2.329E-04 (processing of 20S pre-rRNA) 4.169E-02 (snoRNA binding) 2.538E-04 (nucleolus) 8.743E-02 (MSN2)

REB1(1) AND PAC(1) => SimExpr(YGR280C) OR SimExpr(other) : 5 2

EXPR: (0.150) REB1 (P < 0.000) PAC (P < 0.026)

ORF SYMBOL P F C TF
YOR272W YTM1 chromosome organization and biogenesis (sensu Eukarya), ribosomal large subunit biogenesis ->
chromosome organization and biogenesis (sensu Eukarya), ribosome biogenesis nucleus, nucleolus ->
nucleus, nucleolus LEU3, PUT3, REB1
YOR021C NO SYMBOL ARG80, GCR2
YPL266W DIM1 rRNA modification, 35S primary transcript processing ->
RNA modification, ribosome biogenesis, rRNA metabolism, RNA processing, transcription from Pol I promoter rRNA (adenine-N6\,N6-)-dimethyltransferase activity ->
rRNA (adenine-N6\,N6-)-dimethyltransferase activity nucleolus ->
nucleolus ARG81, STP2
|YKL142W| MRP8 protein biosynthesis ->
protein biosynthesis structural constituent of ribosome ->
structural constituent of ribosome mitochondrial ribosome ->
mitochondrial matrix, organellar ribosome ACE2, CIN5, MBP1, PHO4, REB1, SKN7, STB1
YNL308C KRI1 ribosome biogenesis ->
ribosome biogenesis nucleolus ->
nucleolus
|YML043C| RRN11 transcription from Pol I promoter ->
transcription from Pol I promoter RNA polymerase I transcription factor activity ->
RNA polymerase I transcription factor activity RNA polymerase I transcription factor complex ->
nucleolus, transcription factor complex MAL13
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
ribosome biogenesis, snRNA processing, RNA processing, transcription from Pol I promoter RNA binding ->
RNA binding nucleolus ->
nucleolus
Main: ribosome biogenesis (0.67) RNA binding (0.25) nucleolus (0.83) REB1 (0.40)
Score: 0.53 0.00 0.67 0.100
P-value: 1.591E-03 (ribosome biogenesis) 2.000E+00 1.148E-05 (nucleolus) 3.778E-01 (REB1)

LYS14(1) AND mRRPE(1) AND PAC(1) => SimExpr(YGR280C) OR SimExpr(other) : 7 1

EXPR: (0.135) LYS14 (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.002)

ORF SYMBOL P F C TF
YNL110C NOP15 ribosomal large subunit biogenesis ->
cytoplasm organization and biogenesis nucleus, nucleolus ->
nucleus
YHR052W CIC1 protein catabolism ->
macromolecule catabolism, protein metabolism protein binding\, bridging ->
protein binding\, bridging nucleolus, proteasome complex (sensu Eukarya) ->
nucleus, cytoplasm HAP4, MATa1
|YMR259C| NO SYMBOL ARG80, GCR2, GTS1, HIR1, SRD1
YML093W UTP14 processing of 20S pre-rRNA ->
cytoplasm organization and biogenesis, RNA metabolism, transcription snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
YGL099W LSG1 conjugation with cellular fusion, sporulation (sensu Saccharomyces), ribosome nucleus export ->
conjugation with cellular fusion, sporulation (sensu Fungi), cytoplasm organization and biogenesis, intracellular transport, protein metabolism, protein transport GTPase activity ->
purine nucleotide binding, hydrolase activity\, acting on acid anhydrides cytoplasm ->
cytoplasm PHO4
YJR070C NO SYMBOL GAT3, YAP5
YMR290C HAS1 nucleolus, nuclear membrane ->
nucleus, endomembrane system RAP1
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
cytoplasm organization and biogenesis, RNA metabolism, transcription RNA binding ->
RNA binding nucleolus ->
nucleus
Main: cytoplasm organization and biogenesis (0.80) RNA binding (0.50) nucleus (0.83) GCR2 (0.20)
Score: 0.70 0.17 0.73 0.000
P-value: 3.082E-03 (ribosome biogenesis) 6.400E-01 (RNA binding) 3.460E-05 (nucleolus) 9.544E-01 (MATa1)

RAP1(1) AND MCM1'(1) => SimExpr(YOL120C) OR SimExpr(other) : 15 6

EXPR: (0.133) MCM1' (P < 0.000) RAP1 (P < 0.035)

RAP1(1) AND ALPHA1'(1) AND MCM1'(1) => SimExpr(YOL120C) OR SimExpr(other) : 6 2

EXPR: (0.133) ALPHA1' (P < 0.000) MCM1' (P < 0.000) RAP1 (P < 0.129)

MCM1(1) AND STRE(1) => SimExpr(YKL035W) OR SimExpr(other) : 5 1

EXPR: (0.148) STRE (P < 0.002) MCM1 (P < 0.000)

ORF SYMBOL P F C TF
|YJL079C| PRY1 nuclear membrane, endoplasmic reticulum ->
nuclear membrane, endoplasmic reticulum NDD1, PHD1, RAP1
YJL082W IML2
YLR201C NO SYMBOL ABF1
YMR291W NO SYMBOL RAP1
YKL035W UGP1 protein amino acid glycosylation, UDP-glucose metabolism ->
protein amino acid glycosylation, UDP-glucose metabolism UTP-glucose-1-phosphate uridylyltransferase activity ->
UTP-glucose-1-phosphate uridylyltransferase activity
YOL087C NO SYMBOL DAL82
Main: protein amino acid glycosylation (1.00) UTP-glucose-1-phosphate uridylyltransferase activity (1.00) endoplasmic reticulum (1.00) RAP1 (0.50)
Score: 0.00 0.00 0.00 0.167
P-value: 0.000E+00 0.000E+00 0.000E+00 2.350E-01 (RAP1)

CSRE(1) AND PHO4(1) => SimExpr(YML117W) OR SimExpr(other) : 5 1

EXPR: (0.144) PHO4 (P < 0.007) CSRE (P < 0.000)

CSRE(1) AND mRRPE(1) AND SWI5(1) => SimExpr(YNL111C) OR SimExpr(other) : 8 3

EXPR: (0.168) mRRPE (P < 0.001) SWI5 (P < 0.000) CSRE (P < 0.000)

CSRE(1) AND ALPHA1'(1) AND mRRPE(1) AND SWI5(1) => SimExpr(YNL111C) OR SimExpr(other) : 6 2

EXPR: (0.161) ALPHA1' (P < 0.000) mRRPE (P < 0.000) SWI5 (P < 0.000) CSRE (P < 0.000)

REB1(1) AND PAC(1) => SimExpr(YNL308C) OR SimExpr(other) : 5 2

SFF'(1) AND STE12(1) AND PAC(1) => SimExpr(YNL308C) OR SimExpr(other) : 5 1

EXPR: (0.179) SFF' (P < 0.000) STE12 (P < 0.001) PAC (P < 0.183)

ORF SYMBOL P F C TF
YGR158C MTR3 35S primary transcript processing, mRNA catabolism ->
ribosome biogenesis, mRNA catabolism, RNA processing, transcription from Pol I promoter 3'-5' exoribonuclease activity ->
hydrolase activity\, acting on ester bonds, RNA binding nuclear exosome (RNase complex), cytoplasmic exosome (RNase complex) ->
exosome (RNase complex), cytoplasm, nucleus ZMS1
|YKL142W| MRP8 protein biosynthesis ->
protein biosynthesis structural constituent of ribosome ->
structural constituent of ribosome mitochondrial ribosome ->
cytoplasm, ribonucleoprotein complex ACE2, CIN5, MBP1, PHO4, REB1, SKN7, STB1
YGR251W NO SYMBOL MSN4, PHD1, SKN7
YJL069C UTP18 ABF1
YPR137W RRP9 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
RNA modification, ribosome biogenesis, rRNA metabolism, RNA processing, transcription from Pol I promoter snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex ABF1, HIR1, RCS1
YNL308C KRI1 ribosome biogenesis ->
ribosome biogenesis nucleolus ->
nucleus
Main: ribosome biogenesis (0.75) RNA binding (0.67) nucleus (0.75) ABF1 SKN7 (0.40)
Score: 0.50 0.33 0.83 0.200
P-value: 2.288E-02 (ribosome biogenesis) 3.804E-01 (RNA binding) 1.782E-01 (nucleolus) 2.309E-01 (SKN7)

mRRPE(1) AND STE12(1) AND PAC(1) => SimExpr(YNL308C) : 5

EXPR: (0.142) mRRPE (P < 0.002) STE12 (P < 0.000) PAC (P < 0.012)

ORF SYMBOL P F C TF
YBR247C ENP1 processing of 20S pre-rRNA, rRNA processing, cell growth and/or maintenance ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism snoRNA binding ->
snoRNA binding nucleolus, nucleus ->
nucleolus, nucleus
YMR310C NO SYMBOL
YAL059W ECM1 cell wall organization and biogenesis ->
cell growth and/or maintenance MOT3
YJL069C UTP18 ABF1
YNL308C KRI1 ribosome biogenesis ->
cell growth and/or maintenance nucleolus ->
nucleolus
Main: cell growth and/or maintenance (1.00) snoRNA binding (1.00) nucleolus (1.00) ABF1 (0.50)
Score: 1.00 0.00 1.00 0.000
P-value: 1.424E-01 (ribosome biogenesis) 0.000E+00 9.149E-02 (nucleolus) 1.419E-01 (MOT3)

REB1(1) AND PAC(1) => SimExpr(YPL266W) OR SimExpr(other) : 5 2

REB1(1) AND ALPHA1(1) AND MCM1'(1) => SimExpr(YGR012W) OR SimExpr(other) : 9 4

EXPR: (0.191) REB1 (P < 0.033) MCM1' (P < 0.001) ALPHA1 (P < 0.002)

ORF SYMBOL P F C TF
YLR455W NO SYMBOL
YMR121C RPL15B protein biosynthesis ->
biosynthesis, protein metabolism RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex REB1
YOL148C SPT20 chromatin modification, histone acetylation ->
cell organization and biogenesis, protein metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism protein binding ->
protein binding SAGA complex ->
nucleus GRF10(Pho2), MATa1, MIG1, PHO4
YKR048C NAP1 nucleosome assembly, M phase of mitotic cell cycle ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, cell proliferation protein binding ->
protein binding nucleus ->
nucleus SKN7
YDR073W SNF11 chromatin modeling ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism general RNA polymerase II transcription factor activity ->
general RNA polymerase II transcription factor activity nucleosome remodeling complex, SWI/SNF complex ->
nucleus DAL81, RLM1
YOR152C NO SYMBOL HIR2
|YGR147C| NAT2 N-terminal peptidyl-methionine acetylation ->
protein metabolism, protein modification peptide alpha-N-acetyltransferase activity ->
peptide alpha-N-acetyltransferase activity cytoplasm ->
cytoplasm HIR1, REB1
|YGL097W| SRM1 rRNA-nucleus export, ribosome nucleus export ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism, transport signal transducer activity ->
signal transducer activity nucleus ->
nucleus
YIL112W HOS4 negative regulation of meiosis, histone deacetylation ->
cell proliferation, cell organization and biogenesis, protein metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism NAD-dependent histone deacetylase activity, NAD-independent histone deacetylase activity ->
NAD-dependent histone deacetylase activity, NAD-independent histone deacetylase activity histone deacetylase complex ->
nucleus MAC1, REB1, YFL044C
|YKR011C| NO SYMBOL SWI4, SWI6
YGL237C HAP2 transcription, regulation of carbohydrate metabolism ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, carbohydrate metabolism, energy pathways, regulation of metabolism transcriptional activator activity ->
transcriptional activator activity nucleus, CCAAT-binding factor complex ->
nucleus REB1
|YDL232W| OST4 N-linked glycosylation ->
biosynthesis, protein metabolism dolichyl-diphospho-oligosaccharide-protein glycosyltransferase activity, protein binding ->
dolichyl-diphospho-oligosaccharide-protein glycosyltransferase activity, protein binding endoplasmic reticulum membrane ->
cytoplasm, endomembrane system REB1
YGR012W NO SYMBOL MIG1, REB1
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.67) protein binding (0.33) nucleus (0.67) REB1 (0.55)
Score: 0.75 0.08 0.50 0.291
P-value: 1.495E-02 (DNA packaging) 2.960E-01 (protein binding) 4.345E-02 (transcription factor complex) 5.257E-05 (REB1)

REB1(1) AND ALPHA1(1) AND ALPHA1'(1) AND MCM1'(1) => SimExpr(YGR012W) OR SimExpr(other) : 7 3

EXPR: (0.184) ALPHA1' (P < 0.002) REB1 (P < 0.026) MCM1' (P < 0.001) ALPHA1 (P < 0.001)

ORF SYMBOL P F C TF
YLR455W NO SYMBOL
YMR121C RPL15B protein biosynthesis ->
biosynthesis, protein metabolism RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex REB1
YOL148C SPT20 chromatin modification, histone acetylation ->
cell organization and biogenesis, protein metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism protein binding ->
protein binding SAGA complex ->
nucleus GRF10(Pho2), MATa1, MIG1, PHO4
YKR048C NAP1 nucleosome assembly, M phase of mitotic cell cycle ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, cell proliferation protein binding ->
protein binding nucleus ->
nucleus SKN7
YDR073W SNF11 chromatin modeling ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism general RNA polymerase II transcription factor activity ->
general RNA polymerase II transcription factor activity nucleosome remodeling complex, SWI/SNF complex ->
nucleus DAL81, RLM1
|YGR147C| NAT2 N-terminal peptidyl-methionine acetylation ->
protein metabolism, protein modification peptide alpha-N-acetyltransferase activity ->
peptide alpha-N-acetyltransferase activity cytoplasm ->
cytoplasm HIR1, REB1
YIL112W HOS4 negative regulation of meiosis, histone deacetylation ->
cell proliferation, cell organization and biogenesis, protein metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism NAD-dependent histone deacetylase activity, NAD-independent histone deacetylase activity ->
NAD-dependent histone deacetylase activity, NAD-independent histone deacetylase activity histone deacetylase complex ->
nucleus MAC1, REB1, YFL044C
|YKR011C| NO SYMBOL SWI4, SWI6
|YDL232W| OST4 N-linked glycosylation ->
biosynthesis, protein metabolism dolichyl-diphospho-oligosaccharide-protein glycosyltransferase activity, protein binding ->
dolichyl-diphospho-oligosaccharide-protein glycosyltransferase activity, protein binding endoplasmic reticulum membrane ->
cytoplasm, endomembrane system REB1
YGR012W NO SYMBOL MIG1, REB1
Main: protein metabolism (0.71) protein binding (0.43) nucleus (0.57) REB1 (0.56)
Score: 0.71 0.14 0.43 0.306
P-value: 4.728E-03 (DNA packaging) 1.219E-01 (protein binding) 2.066E-01 (nucleoplasm) 2.104E-04 (REB1)

REB1(1) AND PAC(1) => SimExpr(YOR021C) OR SimExpr(other) : 5 2

ALPHA1'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YOR272W) OR SimExpr(other) : 38 3

EXPR: (0.154) ALPHA1' (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.000)

REB1(1) AND PAC(1) => SimExpr(YOR272W) OR SimExpr(other) : 5 2

CSRE(1) AND SWI5(1) AND PAC(1) => SimExpr(YPR010C) OR SimExpr(other) : 5 1

EXPR: (0.128) SWI5 (P < 0.000) PAC (P < 0.004) CSRE (P < 0.000)

ORF SYMBOL P F C TF
YPR010C RPA135 transcription from Pol I promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DNA-directed RNA polymerase activity ->
DNA-directed RNA polymerase activity DNA-directed RNA polymerase I complex ->
nucleus ROX1, SIG1
YGR245C SDA1 actin cytoskeleton organization and biogenesis, start control point of mitotic cell cycle ->
cell organization and biogenesis, cell proliferation nucleus ->
nucleus
|YKL120W| OAC1 oxaloacetate transport, sulfate transport ->
transport oxaloacetate carrier activity, sulfate porter activity ->
oxaloacetate carrier activity, sulfate porter activity mitochondrial inner membrane ->
cytoplasm, inner membrane LEU3, MTH1
YOR310C NOP58 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex ABF1, SWI6
YDR399W HPT1 purine nucleotide biosynthesis ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism hypoxanthine phosphoribosyltransferase activity ->
hypoxanthine phosphoribosyltransferase activity
YPL143W RPL33A protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, MET4, NDD1, PDR1, RAP1, RME1
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.50) oxaloacetate carrier activity (0.25) nucleus (0.60) ABF1 (0.25)
Score: 0.33 0.00 0.50 0.000
P-value: 2.269E-01 (transcription from Pol I promoter) 9.575E-01 (transferase activity) 1.782E-01 (nucleolus) 7.609E-01 (LEU3)

ABF1(1) AND PAC(1) => SimExpr(YPR010C) OR SimExpr(other) : 12 3

EXPR: (0.153) ABF1 (P < 0.000) PAC (P < 0.004)

ORF SYMBOL P F C TF
YGR283C NO SYMBOL ACE2, RAP1, SMP1
YPR010C RPA135 transcription from Pol I promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DNA-directed RNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups DNA-directed RNA polymerase I complex ->
nucleus ROX1, SIG1
YNL292W PUS4 tRNA modification ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism pseudouridylate synthase activity ->
carbon-oxygen lyase activity mitochondrion, nucleus ->
cytoplasm, nucleus RCS1
YNL112W DBP2 RNA helicase activity ->
RNA binding bud neck ->
site of polarized growth (sensu Fungi)
YKL014C NO SYMBOL ABF1
YKL172W EBP2 rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism nucleolus ->
nucleus ABF1, FZF1, RFX1
YLR197W SIK1 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex, nucleus, nucleolus ->
nucleus, ribonucleoprotein complex DAL81, HAL9
YGR187C HGH1 ABF1, HAP3, HIR1, RCS1, RTG1
YKL078W DHR2 ribosome biogenesis ->
cell organization and biogenesis RNA helicase activity ->
RNA binding nucleolus ->
nucleus ABF1
YOL041C NOP12 rRNA metabolism ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding nucleolus ->
nucleus GTS1, MET31
|YHR027C| RPN1 ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism endopeptidase activity, receptor activity ->
peptidase activity, receptor activity proteasome regulatory particle (sensu Eukarya), endoplasmic reticulum, cytoplasm ->
cytoplasm, nucleus
YJL050W MTR4 35S primary transcript processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus
|YJL069C| UTP18 ABF1
YNR046W NO SYMBOL ABF1
|YDR527W| NO SYMBOL ABF1, SKN7
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.75) RNA binding (0.57) nucleus (0.89) ABF1 (0.58)
Score: 0.64 0.29 0.78 0.333
P-value: 3.084E-02 (transcription from Pol I promoter) 4.360E-03 (RNA helicase activity) 9.555E-05 (nucleolus) 4.241E-04 (ABF1)

CSRE(1) AND mRRPE(1) AND SWI5(1) => SimExpr(YPR010C) OR SimExpr(other) : 8 3

ABF1(1) AND ALPHA1'(1) AND PAC(1) => SimExpr(YPR010C) : 5

EXPR: (0.123) ABF1 (P < 0.000) ALPHA1' (P < 0.000) PAC (P < 0.017)

CSRE(1) AND mRRPE(1) AND PAC(1) => SimExpr(YPR010C) : 5

EXPR: (0.093) mRRPE (P < 0.000) PAC (P < 0.001) CSRE (P < 0.000)

ORF SYMBOL P F C TF
YPR010C RPA135 transcription from Pol I promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DNA-directed RNA polymerase activity ->
DNA-directed RNA polymerase activity DNA-directed RNA polymerase I complex ->
nucleus ROX1, SIG1
YGR245C SDA1 actin cytoskeleton organization and biogenesis, start control point of mitotic cell cycle ->
cell organization and biogenesis, cell proliferation nucleus ->
nucleus
YGR159C NSR1 ribosomal small subunit assembly and maintenance, rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism single-stranded DNA binding, RNA binding ->
single-stranded DNA binding, RNA binding nucleolus, nucleus ->
nucleus
YOR310C NOP58 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex ABF1, SWI6
YDR399W HPT1 purine nucleotide biosynthesis ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism hypoxanthine phosphoribosyltransferase activity ->
hypoxanthine phosphoribosyltransferase activity
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.80) RNA binding (0.33) nucleus (1.00) ABF1 (0.50)
Score: 0.80 0.00 1.00 0.000
P-value: 7.183E-03 (transcription from Pol I promoter) 7.087E-01 (transferase activity) 3.698E-03 (nucleolus) 2.284E-01 (SIG1)

mRRPE(1) AND PAC(1) => SimExpr(YOR310C) OR SimExpr(other) : 56 20

CSRE(1) AND mRRPE(1) AND SWI5(1) => SimExpr(YOR310C) OR SimExpr(other) : 8 3

mRRPE(1) AND SWI5(1) AND PAC(1) => SimExpr(YOR310C) OR SimExpr(other) : 11 5

mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YOR310C) OR SimExpr(other) : 16 4

ALPHA1'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YOR310C) OR SimExpr(other) : 30 11

CSRE(1) AND SWI5(1) AND PAC(1) => SimExpr(YOR310C) OR SimExpr(other) : 5 1

SFF'(1) AND mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YOR310C) OR SimExpr(other) : 9 2

EXPR: (0.131) SFF' (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.001) SCB (P < 0.000)

ALPHA1'(1) AND mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YOR310C) OR SimExpr(other) : 7 1

EXPR: (0.131) ALPHA1' (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.001) SCB (P < 0.000)

ORF SYMBOL P F C TF
|YNL292W| PUS4 tRNA modification ->
RNA processing, tRNA metabolism pseudouridylate synthase activity ->
carbon-oxygen lyase activity mitochondrion, nucleus ->
cytoplasm, nucleus RCS1
YNL112W DBP2 RNA helicase activity ->
RNA binding bud neck ->
site of polarized growth (sensu Fungi)
YDR184C ATC1 response to stress, polar budding ->
response to stress, polar budding nucleus ->
nucleus ARO80, GLN3, SIP4, SKO1
YOR078W BUD21 processing of 20S pre-rRNA ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex ABF1, MSS11, SIG1, SKO1
YJL109C UTP10 processing of 20S pre-rRNA ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
YJR070C NO SYMBOL GAT3, YAP5
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent RNA binding ->
RNA binding nucleolus ->
nucleus
YOR310C NOP58 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
RNA processing, ribosome biogenesis and assembly, rRNA metabolism, transcription\, DNA-dependent small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex ABF1, SWI6
Main: RNA processing (0.83) RNA binding (0.80) nucleus (0.86) ABF1 SKO1 (0.40)
Score: 0.67 0.60 0.71 0.200
P-value: 7.533E-04 (processing of 20S pre-rRNA) 7.782E-03 (snoRNA binding) 2.268E-04 (small nucleolar ribonucleoprotein complex) 2.853E-02 (SKO1)

ALPHA1'(1) AND mRRPE(1) AND SWI5(1) AND PAC(1) => SimExpr(YOR310C) OR SimExpr(other) : 8 2

EXPR: (0.154) ALPHA1' (P < 0.000) mRRPE (P < 0.002) SWI5 (P < 0.000) PAC (P < 0.013)

mRRPE(1) AND SWI5(1) AND PAC(1) AND SCB(1) => SimExpr(YOR310C) OR SimExpr(other) : 5 1

EXPR: (0.117) mRRPE (P < 0.000) SWI5 (P < 0.000) PAC (P < 0.001) SCB (P < 0.000)

ORF SYMBOL P F C TF
|YMR259C| NO SYMBOL ARG80, GCR2, GTS1, HIR1, SRD1
YJL109C UTP10 processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
YLR249W YEF3 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
translation factor activity\, nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex INO2, INO4
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding nucleolus ->
nucleus
YOR310C NOP58 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex ABF1, SWI6
YDR399W HPT1 purine nucleotide biosynthesis ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism hypoxanthine phosphoribosyltransferase activity ->
transferase activity\, transferring glycosyl groups
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.80) RNA binding (0.50) nucleus (0.75) ABF1 (0.33)
Score: 0.70 0.17 0.83 0.000
P-value: 9.864E-03 (rRNA processing) 3.308E-01 (nucleic acid binding) 8.330E-03 (small nucleolar ribonucleoprotein complex) 7.610E-01 (SRD1)

CSRE(1) AND mRRPE(1) AND PAC(1) => SimExpr(YOR310C) : 5

CSRE(1) AND ALPHA1'(1) AND mRRPE(1) AND SWI5(1) => SimExpr(YOR063W) OR SimExpr(other) : 6 2

ABF1(1) AND RPN4(1) => SimExpr(YGR253C) OR SimExpr(other) : 6 1

EXPR: (0.152) ABF1 (P < 0.000) RPN4 (P < 0.047)

ORF SYMBOL P F C TF
YFR020W NO SYMBOL MIG1
|YNL251C| NRD1 nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding nucleus ->
nucleus ABF1, MAC1
YJR006W HYS2 leading strand elongation, lagging strand elongation, mutagenesis, base-excision repair, nucleotide-excision repair, postreplication repair, mismatch repair ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, DNA repair, cell proliferation delta DNA polymerase activity ->
delta DNA polymerase activity delta DNA polymerase complex ->
cytoplasm, nucleus ABF1
YHR027C RPN1 ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism endopeptidase activity, receptor activity ->
endopeptidase activity, receptor activity proteasome regulatory particle (sensu Eukarya), endoplasmic reticulum, cytoplasm ->
cytoplasm, nucleus
YGR253C PUP2 ubiquitin-dependent protein catabolism, response to stress, sporulation (sensu Saccharomyces) ->
catabolism, response to stress, sporulation, protein metabolism endopeptidase activity ->
endopeptidase activity proteasome core complex (sensu Eukarya) ->
cytoplasm, nucleus ABF1, HIR2, PHO4
YHL024W RIM4 sporulation, meiosis, premeiotic DNA synthesis, meiotic recombination ->
sporulation, M phase, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, cell proliferation RNA binding ->
RNA binding cytoplasm ->
cytoplasm FKH2, PHD1
YOR362C PRE10 ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism endopeptidase activity ->
endopeptidase activity proteasome core complex (sensu Eukarya) ->
cytoplasm, nucleus
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.50) endopeptidase activity (0.50) cytoplasm (0.83) ABF1 (0.60)
Score: 0.47 0.27 0.93 0.300
P-value: 1.746E-02 (ubiquitin-dependent protein catabolism) 7.474E-04 (endopeptidase activity) 6.518E-04 (proteasome complex (sensu Eukarya)) 6.278E-02 (ABF1)

CSRE(1) AND SWI5(1) AND PAC(1) => SimExpr(YDR399W) OR SimExpr(other) : 5 1

CSRE(1) AND mRRPE(1) AND PAC(1) => SimExpr(YDR399W) : 5

ALPHA2(1) AND ABF1(1) => SimExpr(YGL207W) OR SimExpr(other) : 9 4

EXPR: (0.190) ALPHA2 (P < 0.006) ABF1 (P < 0.075)

ORF SYMBOL P F C TF
YDL195W SEC31 ER to Golgi transport ->
transport, vesicle-mediated transport structural molecule activity ->
structural molecule activity COPII vesicle coat ->
cytoplasm ABF1, GAT1, MTH1, SFL1, SIG1
YLR429W CRN1 actin filament organization, microtubule-based process ->
cell organization and biogenesis actin cross-linking activity, microtubule binding ->
actin cross-linking activity, microtubule binding actin cortical patch (sensu Saccharomyces) ->
cell cortex, cytoplasm
|YJL097W| NO SYMBOL ARG80, HAP3
|YNL111C| CYB5 sterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism electron transporter activity ->
electron transporter activity microsome ->
membrane fraction ABF1, GCR2, GTS1, NRG1, REB1, ROX1
YKR046C PET10 lipid particle ->
cytoplasm ABF1
YGL207W SPT16 chromatin modeling, regulation of global transcription from Pol II promoter, RNA elongation from Pol II promoter ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, DNA metabolism transcriptional elongation regulator activity ->
transcriptional elongation regulator activity alpha DNA polymerase\:primase complex, nuclear chromatin, transcription elongation factor complex ->
nucleus, chromosome RTG1
|YKL172W| EBP2 rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism nucleolus ->
nucleus ABF1, FZF1, RFX1
YAL016W TPD3 protein biosynthesis, actin filament organization, mitotic spindle checkpoint, bud growth, protein amino acid dephosphorylation ->
biosynthesis, cell organization and biogenesis, asexual reproduction, phosphorus metabolism, cell proliferation, cell cycle, protein metabolism protein phosphatase type 2A activity ->
protein phosphatase type 2A activity protein phosphatase type 2A complex, bud neck, nucleus, cytoplasm, shmoo tip, bud tip, spindle pole body ->
protein phosphatase type 2A complex, nucleus, site of polarized growth (sensu Fungi), site of polarized growth (sensu Saccharomyces), cytoplasm, microtubule organizing center ABF1
YJL091C GWT1 GPI anchor biosynthesis ->
biosynthesis, membrane lipid metabolism, protein metabolism, lipid metabolism membrane ->
membrane
YHR027C RPN1 ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism endopeptidase activity, receptor activity ->
endopeptidase activity, receptor activity proteasome regulatory particle (sensu Eukarya), endoplasmic reticulum, cytoplasm ->
cytoplasm, nucleus
YKR084C HBS1 protein biosynthesis ->
biosynthesis, protein metabolism PHO4
|YNR046W| NO SYMBOL ABF1
YNL059C ARP5 protein-vacuolar targeting ->
cell organization and biogenesis, protein metabolism, transport nucleus ->
nucleus ABF1, GRF10(Pho2)
Main: cell organization and biogenesis (0.50) electron transporter activity (0.17) cytoplasm (0.50) ABF1 (0.70)
Score: 0.51 0.00 0.42 0.467
P-value: 3.890E-01 (actin filament organization) 2.991E+00 (hydrolase activity) 1.171E+00 (cytoskeleton) 1.272E-04 (ABF1)

SFF(1) AND MCB(1) AND ATRepeat(1) => SimExpr(YJR006W) OR SimExpr(other) : 6 2

EXPR: (0.171) SFF (P < 0.000) MCB (P < 0.030) ATRepeat (P < 0.005)

ORF SYMBOL P F C TF
YDL003W MCD1 mitotic sister chromatid cohesion, mitotic chromosome condensation ->
cell proliferation, cell cycle nuclear cohesin complex ->
chromosome, nucleus CIN5, MBP1, SWI6
YPR185W APG13 protein-vacuolar targeting, autophagy ->
cell organization and biogenesis, autophagy, protein metabolism, transport protein binding ->
protein binding extrinsic to membrane ->
extrinsic to membrane MET4, SWI6
YLR212C TUB4 microtubule nucleation, mitotic spindle assembly (sensu Saccharomyces) ->
cell organization and biogenesis, cell proliferation, cell cycle structural constituent of cytoskeleton ->
structural constituent of cytoskeleton inner plaque of spindle pole body, outer plaque of spindle pole body ->
cytoplasm
YPL123C RNY1 cellular morphogenesis ->
cell organization and biogenesis endoribonuclease activity ->
hydrolase activity\, acting on ester bonds, RNA binding extracellular ->
extracellular ARG80, CUP9, DAL81, FZF1, NRG1, STB1
YJR006W HYS2 leading strand elongation, lagging strand elongation, mutagenesis, base-excision repair, nucleotide-excision repair, postreplication repair, mismatch repair ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, DNA repair, cell proliferation delta DNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups delta DNA polymerase complex ->
cytoplasm, nucleus ABF1
|YNL102W| POL1 DNA replication\, priming, DNA replication initiation, lagging strand elongation, DNA repair synthesis ->
DNA metabolism, cell proliferation alpha DNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups alpha DNA polymerase\:primase complex ->
nucleus LEU3, MBP1
YLR430W SEN1 35S primary transcript processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus ARG80, GTS1, HAP5, RTG3, SIP4
|YMR102C| NO SYMBOL
Main: cell organization and biogenesis (0.57) RNA binding (0.33) nucleus (0.57) ARG80 MBP1 SWI6 (0.33)
Score: 0.62 0.13 0.33 0.200
P-value: 3.346E-03 (lagging strand elongation) 1.223E-02 (DNA-directed DNA polymerase activity) 1.056E-02 (replication fork) 1.376E-01 (ARG80)

CSRE(1) AND PHO4(1) => SimExpr(YOR299W) OR SimExpr(other) : 5 1

mRRPE(1) AND PAC(1) => SimExpr(YGR159C) OR SimExpr(other) : 52 24

CSRE(1) AND mRRPE(1) AND PAC(1) => SimExpr(YGR159C) : 5

CSRE(1) AND mRRPE(1) AND PAC(1) => SimExpr(YGR245C) : 5

CSRE(1) AND OAF1(1) => SimExpr(YJR019C) OR SimExpr(other) : 5 1

EXPR: (0.153) OAF1 (P < 0.010) CSRE (P < 0.001)

ORF SYMBOL P F C TF
YJR019C TES1 fatty acid oxidation ->
lipid metabolism, carboxylic acid metabolism acyl-CoA thioesterase activity ->
acyl-CoA thioesterase activity peroxisome ->
cytoplasm DAL82, MTH1
YLR174W IDP2 isocitrate metabolism, glutamate biosynthesis ->
carbohydrate metabolism, amine biosynthesis, amine metabolism, carboxylic acid metabolism, energy derivation by oxidation of organic compounds, amino acid and derivative metabolism isocitrate dehydrogenase (NADP+) activity ->
isocitrate dehydrogenase (NADP+) activity cytosol ->
cytoplasm ABF1, CBF1, RAP1
YMR135C GID8 negative regulation of gluconeogenesis ->
alcohol biosynthesis, regulation of biosynthesis, monosaccharide metabolism, carbohydrate metabolism, negative regulation of metabolism, carbohydrate biosynthesis, energy derivation by oxidation of organic compounds, regulation of metabolism ASH1, CUP9, DAL81, INO4, NDD1, NRG1, PHD1, ROX1, SKN7, SWI4, YAP6
|YDR134C| NO SYMBOL ASH1, NRG1, SOK2, SWI4
YNL329C PEX6 peroxisome organization and biogenesis ->
cytoplasm organization and biogenesis ATPase activity ->
ATPase activity peroxisome ->
cytoplasm RAP1
YML042W CAT2 carnitine metabolism ->
amine metabolism, carboxylic acid metabolism, water-soluble vitamin metabolism, amino acid derivative metabolism carnitine O-acetyltransferase activity ->
carnitine O-acetyltransferase activity peroxisomal matrix, mitochondrion, peroxisome ->
cytoplasm MAL13
Main: carboxylic acid metabolism (0.60) ATPase activity (0.25) cytoplasm (1.00) SWI4 RAP1 ASH1 NRG1 (0.33)
Score: 0.40 0.00 1.00 0.133
P-value: 4.936E-02 (organic acid metabolism) 1.308E+00 (hydrolase activity) 2.629E-04 (peroxisome) 2.324E-02 (ASH1)

RAP1(1) AND SCB(1) => SimExpr(YLR344W) OR SimExpr(other) : 10 2

EXPR: (0.145) SCB (P < 0.000) RAP1 (P < 0.093)

RAP1(1) AND MCM1'(1) => SimExpr(YLR344W) OR SimExpr(other) : 16 5

RAP1(1) AND SWI5(1) => SimExpr(YLR344W) OR SimExpr(other) : 16 7

EXPR: (0.164) SWI5 (P < 0.000) RAP1 (P < 0.395)

RAP1(1) AND SWI5(1) AND MCM1'(1) => SimExpr(YLR344W) : 7

EXPR: (0.110) SWI5 (P < 0.000) MCM1' (P < 0.000) RAP1 (P < 0.005)

RAP1(1) AND ALPHA1'(1) AND SCB(1) => SimExpr(YLR344W) : 6

EXPR: (0.117) ALPHA1' (P < 0.000) SCB (P < 0.000) RAP1 (P < 0.027)

RAP1(1) AND SWI5(1) AND SCB(1) => SimExpr(YLR344W) : 5

EXPR: (0.111) SWI5 (P < 0.000) SCB (P < 0.000) RAP1 (P < 0.015)

RPN4(1) => SimExpr(YGL201C) OR SimExpr(other) : 35 17

EXPR: (0.190) RPN4 (P < 0.547)

ALPHA1(1) AND RPN4(1) => SimExpr(YGL201C) OR SimExpr(other) : 13 6

EXPR: (0.188) RPN4 (P < 0.477) ALPHA1 (P < 0.000)

ALPHA1(1) AND LYS14(1) AND RPN4(1) => SimExpr(YGL201C) OR SimExpr(other) : 5 1

EXPR: (0.174) LYS14 (P < 0.001) RPN4 (P < 0.258) ALPHA1 (P < 0.000)

ORF SYMBOL P F C TF
YGL201C MCM6 DNA unwinding, DNA replication initiation ->
cell cycle, DNA metabolism chromatin binding, ATP dependent DNA helicase activity ->
chromatin binding, ATP dependent DNA helicase activity cytoplasm, nucleus, pre-replicative complex ->
cytoplasm, nucleus MCM1
YNL097C PHO23 chromatin modification ->
nuclear organization and biogenesis, DNA metabolism nucleus ->
nucleus MAC1
|YGR060W| ERG25 ergosterol biosynthesis ->
alcohol metabolism, lipid biosynthesis, steroid metabolism C-4 methyl sterol oxidase activity ->
C-4 methyl sterol oxidase activity endoplasmic reticulum membrane, plasma membrane ->
cytoplasm, plasma membrane, endomembrane system HSF1, MAL13, MET4, NDD1, SWI5
YGR253C PUP2 ubiquitin-dependent protein catabolism, response to stress, sporulation (sensu Saccharomyces) ->
macromolecule catabolism, response to stress, sporulation (sensu Fungi), protein metabolism endopeptidase activity ->
endopeptidase activity proteasome core complex (sensu Eukarya) ->
cytoplasm, nucleus ABF1, HIR2, PHO4
YOR052C NO SYMBOL
YKL054C DEF1 response to DNA damage, ubiquitin-dependent protein catabolism ->
response to stress, macromolecule catabolism, protein metabolism nucleus ->
nucleus
Main: DNA metabolism (0.40) chromatin binding (0.33) nucleus (0.80) ABF1 (0.25)
Score: 0.20 0.00 0.80 0.000
P-value: 1.924E-01 (ubiquitin-dependent protein catabolism) 1.308E+00 (hydrolase activity) 4.424E-01 (endoplasmic reticulum) 6.578E-01 (MAL13)

ALPHA1'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YGL029W) OR SimExpr(other) : 35 6

ALPHA1(1) AND mRRPE(1) AND PAC(1) => SimExpr(YGL029W) OR SimExpr(other) : 19 3

EXPR: (0.162) mRRPE (P < 0.000) PAC (P < 0.015) ALPHA1 (P < 0.000)

MCM1(1) AND STRE(1) => SimExpr(YOL087C) OR SimExpr(other) : 5 1

ALPHA1(1) AND ALPHA1'(1) AND STRE(1) => SimExpr(YOL087C) OR SimExpr(other) : 5 2

EXPR: (0.177) ALPHA1' (P < 0.002) STRE (P < 0.035) ALPHA1 (P < 0.003)

ORF SYMBOL P F C TF
YPR184W GDB1 glycogen catabolism ->
carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism 4-alpha-glucanotransferase activity, amylo-1\,6-glucosidase activity ->
transferase activity\, transferring hexosyl groups, hydrolase activity\, hydrolyzing O-glycosyl compounds CIN5
YOL087C NO SYMBOL DAL82
|YNL098C| RAS2 pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction ->
cell organization and biogenesis, sporulation, signal transduction RAS small monomeric GTPase activity ->
guanyl nucleotide binding, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides plasma membrane ->
plasma membrane ACE2, SKN7
|YIL052C| RPL34B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex RME1
YGL062W PYC1 NADPH regeneration, gluconeogenesis ->
coenzymes and prosthetic group metabolism, alcohol metabolism, carbohydrate metabolism, vitamin metabolism, biosynthesis, energy pathways pyruvate carboxylase activity ->
pyruvate carboxylase activity cytosol ->
cytoplasm DIG1, GCR1, STE12
YKL035W UGP1 protein amino acid glycosylation, UDP-glucose metabolism ->
biosynthesis, alcohol metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism, carbohydrate metabolism UTP-glucose-1-phosphate uridylyltransferase activity ->
nucleotidyltransferase activity
YFL036W RPO41 mitochondrial genome maintenance, transcription from mitochondrial promoter ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DNA-directed RNA polymerase activity ->
nucleotidyltransferase activity mitochondrial matrix ->
cytoplasm
Main: biosynthesis (0.50) nucleotidyltransferase activity (0.33) cytoplasm (0.75) ACE2 (0.20)
Score: 0.47 0.07 0.50 0.000
P-value: 9.418E-02 (carbohydrate metabolism) 4.324E-02 (nucleotidyltransferase activity) 1.068E+00 (cytosol) 5.887E-01 (DAL82)

RAP1(1) AND MCM1'(1) => SimExpr(YGR085C) OR SimExpr(other) : 15 6

MIG1(1) AND ABF1(1) => SimExpr(YKR046C) OR SimExpr(other) : 7 2

EXPR: (0.171) ABF1 (P < 0.000) MIG1 (P < 0.005)

ORF SYMBOL P F C TF
YNL138W SRV2 cytoskeleton organization and biogenesis, RAS protein signal transduction ->
cell organization and biogenesis, signal transduction cytoskeletal protein binding, adenylate cyclase binding ->
cytoskeletal protein binding, adenylate cyclase binding actin cortical patch (sensu Saccharomyces) ->
intracellular ABF1
|YMR280C| CAT8 gluconeogenesis, positive regulation of transcription from Pol II promoter ->
alcohol metabolism, monosaccharide metabolism, carbohydrate metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, biosynthesis, energy pathways specific RNA polymerase II transcription factor activity ->
specific RNA polymerase II transcription factor activity nucleus ->
intracellular ABF1, REB1
YOR317W FAA1 N-terminal protein myristoylation, lipid metabolism, lipid transport ->
biosynthesis, lipid metabolism, transport, protein metabolism ligase activity ->
ligase activity lipid particle ->
intracellular ASH1, CIN5, HSF1, INO4, RAP1
YKR046C PET10 lipid particle ->
intracellular ABF1
YAL016W TPD3 protein biosynthesis, actin filament organization, mitotic spindle checkpoint, bud growth, protein amino acid dephosphorylation ->
biosynthesis, cell organization and biogenesis, asexual reproduction, phosphorus metabolism, cell proliferation, cell cycle, protein metabolism protein phosphatase type 2A activity ->
protein phosphatase type 2A activity protein phosphatase type 2A complex, bud neck, nucleus, cytoplasm, shmoo tip, bud tip, spindle pole body ->
protein phosphatase type 2A complex, site of polarized growth (sensu Fungi), site of polarized growth (sensu Saccharomyces), intracellular ABF1
YKL034W TUL1 protein transport ->
transport ligase activity ->
ligase activity intracellular ->
intracellular
YPL111W CAR1 arginine catabolism to ornithine ->
amine metabolism, nitrogen metabolism, amino acid and derivative metabolism, organic acid metabolism, catabolism arginase activity ->
arginase activity cytosol ->
intracellular GCN4
YOR322C NO SYMBOL ABF1
|YDL020C| RPN4 ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism endopeptidase activity ->
endopeptidase activity proteasome regulatory particle (sensu Eukarya) ->
intracellular ABF1, CBF1, HSF1, PUT3, YAP1
Main: biosynthesis (0.43) ligase activity (0.29) intracellular (1.00) ABF1 (0.75)
Score: 0.38 0.05 1.00 0.571
P-value: 1.690E+00 (cytoskeleton organization and biogenesis) 1.516E-01 (ligase activity) 2.216E-02 (lipid particle) 7.301E-05 (ABF1)

ALPHA1(1) AND ALPHA1'(1) AND STRE(1) => SimExpr(YPR184W) OR SimExpr(other) : 5 2

MIG1(1) AND ABF1(1) => SimExpr(YAL016W) OR SimExpr(other) : 7 2

mRRPE(1) AND PAC(1) => SimExpr(YOR095C) OR SimExpr(other) : 57 19

mRRPE(1) AND PAC(1) AND MCM1'(1) => SimExpr(YOR095C) OR SimExpr(other) : 10 4

ALPHA1(1) AND mRRPE(1) AND PAC(1) => SimExpr(YOR095C) OR SimExpr(other) : 16 6

SFF(1) AND MCB(1) AND ATRepeat(1) => SimExpr(YPR185W) OR SimExpr(other) : 6 2

RAP1(1) AND SFF(1) AND SWI5(1) => SimExpr(YMR194W) OR SimExpr(other) : 10 4

EXPR: (0.169) SFF (P < 0.000) SWI5 (P < 0.000) RAP1 (P < 0.059)

RAP1(1) AND ALPHA1'(1) AND SCB(1) => SimExpr(YMR194W) : 6

RAP1(1) AND PAC(1) => SimExpr(YGR283C) : 5

EXPR: (0.145) PAC (P < 0.008) RAP1 (P < 0.004)

ORF SYMBOL P F C TF
YMR014W BUD22 bud site selection ->
cytokinesis, cytoplasm organization and biogenesis nucleus ->
nucleus CUP9, HAL9, HIR2, LEU3, NDD1, RLM1, ROX1, SMP1, YAP6
YGR283C NO SYMBOL ACE2, RAP1, SMP1
YKR092C SRP40 nucleocytoplasmic transport ->
intracellular transport chaperone activity ->
chaperone activity nucleolus ->
nucleus CUP9, MET4, RAP1
YLR249W YEF3 translational elongation ->
macromolecule biosynthesis, protein metabolism translation elongation factor activity ->
translation elongation factor activity ribosome ->
cytoplasm, ribonucleoprotein complex INO2, INO4
YDR449C UTP6 processing of 20S pre-rRNA ->
cytoplasm organization and biogenesis, RNA metabolism, transcription snoRNA binding ->
snoRNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex FHL1, GAT3, HIR2, RAP1, RGM1, YAP5
Main: cytoplasm organization and biogenesis (0.50) translation elongation factor activity (0.33) nucleus (0.75) RAP1 (0.60)
Score: 0.17 0.00 0.67 0.600
P-value: 1.792E+00 (cytoplasm organization and biogenesis) 8.180E-01 (nucleic acid binding) 1.067E-01 (nucleolus) 3.225E-02 (HIR2)

RAP1(1) AND SFF(1) AND SWI5(1) => SimExpr(YOR369C) OR SimExpr(other) : 10 4

RAP1(1) AND SWI5(1) AND SCB(1) => SimExpr(YOR369C) : 5

RAP1(1) AND ALPHA1'(1) AND SCB(1) => SimExpr(YOR369C) : 6

RAP1(1) AND MCM1'(1) => SimExpr(YDL130W) OR SimExpr(other) : 15 6

RAP1(1) AND ALPHA1'(1) AND SCB(1) => SimExpr(YPL131W) OR SimExpr(other) : 5 1

RAP1(1) AND SFF'(1) AND SCB(1) => SimExpr(YPL131W) OR SimExpr(other) : 7 3

EXPR: (0.160) SFF' (P < 0.000) SCB (P < 0.000) RAP1 (P < 0.170)

RAP1(1) AND SFF(1) AND SCB(1) => SimExpr(YPL131W) OR SimExpr(other) : 7 2

EXPR: (0.152) SFF (P < 0.000) SCB (P < 0.000) RAP1 (P < 0.136)

RAP1(1) AND ALPHA1'(1) AND SFF(1) AND SCB(1) => SimExpr(YPL131W) : 5

EXPR: (0.116) ALPHA1' (P < 0.000) SFF (P < 0.000) SCB (P < 0.000) RAP1 (P < 0.042)

RAP1(1) AND ALPHA1'(1) AND SFF'(1) AND SCB(1) => SimExpr(YPL131W) : 5

EXPR: (0.116) ALPHA1' (P < 0.000) SFF' (P < 0.000) SCB (P < 0.000) RAP1 (P < 0.043)

RAP1(1) AND ALPHA1'(1) AND SCB(1) => SimExpr(YNL024C) : 6

RAP1(1) AND MCM1'(1) => SimExpr(YKL006W) OR SimExpr(other) : 15 6

ALPHA2(1) AND mRRPE(1) AND PAC(1) => SimExpr(YLR249W) OR SimExpr(other) : 7 2

EXPR: (0.135) ALPHA2 (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.009)

ORF SYMBOL P F C TF
YKL172W EBP2 rRNA processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent nucleolus ->
nucleus ABF1, FZF1, RFX1
|YJL033W| HCA4 35S primary transcript processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus HIR2, USV1
YMR049C ERB1 rRNA processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent RTG3
YLR249W YEF3 translational elongation ->
protein biosynthesis translation elongation factor activity ->
translation factor activity\, nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex INO2, INO4
YGL029W CGR1 ribosome biogenesis, rRNA processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent nucleolus ->
nucleus
YJR070C NO SYMBOL GAT3, YAP5
YLR222C UTP13 processing of 20S pre-rRNA ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex ABF1
|YPR183W| DPM1 N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
phospholipid biosynthesis, protein biosynthesis, glycerophospholipid metabolism, protein modification, glycoprotein metabolism, lipoprotein metabolism transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
cytoplasm, endomembrane system SWI5
YNR046W NO SYMBOL ABF1
Main: RNA processing (0.71) RNA binding (0.50) nucleus (0.67) ABF1 (0.38)
Score: 0.52 0.17 0.53 0.107
P-value: 5.052E-05 (rRNA processing) 9.380E-01 (RNA binding) 2.195E-03 (nucleolus) 2.138E-01 (ABF1)

RAP1(1) AND SFF(1) AND SWI5(1) => SimExpr(YLR249W) OR SimExpr(other) : 10 4

RAP1(1) AND ALPHA1'(1) AND SCB(1) => SimExpr(YPR080W) OR SimExpr(other) : 5 1

RPN4(1) => SimExpr(YDL126C) OR SimExpr(other) : 35 17

LYS14(1) AND mRRPE(1) AND PAC(1) => SimExpr(YMR290C) OR SimExpr(other) : 7 1

SFF'(1) AND STE12(1) AND PAC(1) => SimExpr(YJL069C) OR SimExpr(other) : 5 1

ALPHA1(1) AND RPN4(1) => SimExpr(YOR052C) OR SimExpr(other) : 13 6

mRRPE(1) AND SWI5(1) AND PAC(1) AND SCB(1) => SimExpr(YJL109C) OR SimExpr(other) : 5 1

ALPHA1(1) AND ALPHA1'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YJL109C) OR SimExpr(other) : 9 4

EXPR: (0.192) ALPHA1' (P < 0.000) mRRPE (P < 0.002) PAC (P < 0.024) ALPHA1 (P < 0.000)

ALPHA1(1) AND RPN4(1) => SimExpr(YKL145W) OR SimExpr(other) : 13 6

ALPHA1'(1) AND GCN4(1) AND SCB(1) => SimExpr(YDR473C) OR SimExpr(other) : 5 2

EXPR: (0.175) ALPHA1' (P < 0.000) GCN4 (P < 0.028) SCB (P < 0.002)

ORF SYMBOL P F C TF
YFL028C CAF16 regulation of transcription\, DNA-dependent ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ATP-binding cassette (ABC) transporter activity ->
ATP-binding cassette (ABC) transporter activity CCR4-NOT complex, cytoplasm ->
nucleus, cytoplasm
YFR028C CDC14 DNA dependent DNA replication, protein amino acid dephosphorylation, regulation of exit from mitosis ->
phosphorus metabolism, cell cycle, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism protein phosphatase activity ->
protein phosphatase activity nucleus, spindle pole body, nucleolus ->
cytoplasm, nucleus, microtubule organizing center
|YMR300C| ADE4 purine base metabolism ->
aromatic compound metabolism, heterocycle metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism amidophosphoribosyltransferase activity ->
amidophosphoribosyltransferase activity BAS1
YDR473C PRP3 mRNA splicing ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism pre-mRNA splicing factor activity ->
pre-mRNA splicing factor activity small nuclear ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex ARG80, ARG81, DOT6, FZF1, GCR2, HAP4, HAP5, NRG1, RIM101, RLM1, RTG1, RTG3, SFP1, SRD1, STP1, THI2
YLR271W NO SYMBOL
YKL211C TRP3 tryptophan biosynthesis ->
amine metabolism, aromatic compound biosynthesis, aromatic compound metabolism, amino acid and derivative metabolism, biosynthesis, organic acid metabolism, heterocycle metabolism anthranilate synthase activity, indole-3-glycerol-phosphate synthase activity ->
anthranilate synthase activity, indole-3-glycerol-phosphate synthase activity CRZ1
|YPR145W| ASN1 asparagine biosynthesis ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis asparagine synthase (glutamine-hydrolyzing) activity ->
asparagine synthase (glutamine-hydrolyzing) activity DAL81, GCN4, GLN3, MET4, RAP1, SUM1
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.67) pre-mRNA splicing factor activity (0.17) nucleus (1.00) GCR2 (0.25)
Score: 0.53 0.00 1.00 0.000
P-value: 4.613E-02 (aromatic compound metabolism) 1.306E+00 (enzyme activity) 2.826E+00 (nucleus) 1.000E+00

ALPHA1(1) AND RPN4(1) => SimExpr(YNL097C) OR SimExpr(other) : 14 5

LYS14(1) AND ALPHA1'(1) AND PAC(1) => SimExpr(YJR070C) OR SimExpr(other) : 6 2

EXPR: (0.181) LYS14 (P < 0.000) ALPHA1' (P < 0.000) PAC (P < 0.139)

ORF SYMBOL P F C TF
YGR191W HIP1 manganese ion transport, histidine transport ->
transport, organic acid transport histidine transporter activity ->
carboxylic acid transporter activity plasma membrane ->
plasma membrane GLN3, HAP3, HIR2, MBP1, MCM1, REB1, YAP1
|YGR178C| PBP1 mRNA polyadenylation ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism cytoplasm, nucleus ->
cytoplasm, nucleus CIN5, DOT6, MSS11
YML093W UTP14 processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
YDR361C BCP1 ABF1, ARO80, GLN3, HAP5, IXR1, YAP1
YGL099W LSG1 conjugation with cellular fusion, sporulation (sensu Saccharomyces), ribosome nucleus export ->
conjugation, sporulation, cell organization and biogenesis, protein metabolism, transport, sexual reproduction GTPase activity ->
purine nucleotide binding, hydrolase activity\, acting on acid anhydrides cytoplasm ->
cytoplasm PHO4
|YOL075C| NO SYMBOL CRZ1, DAL82, SIP4
YJR070C NO SYMBOL GAT3, YAP5
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding nucleolus ->
nucleus
Main: cell organization and biogenesis (0.60) RNA binding (0.50) nucleus (0.60) YAP1 GLN3 (0.33)
Score: 0.60 0.17 0.40 0.067
P-value: 6.030E-02 (ribosome biogenesis) 6.400E-01 (RNA binding) 2.761E-01 (nucleolus) 9.199E-02 (GLN3)

ALPHA2(1) AND ALPHA1'(1) AND PAC(1) => SimExpr(YLR222C) OR SimExpr(other) : 5 2

EXPR: (0.165) ALPHA2 (P < 0.000) ALPHA1' (P < 0.000) PAC (P < 0.120)

ORF SYMBOL P F C TF
YJL033W HCA4 35S primary transcript processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus HIR2, USV1
YMR049C ERB1 rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RTG3
YGL029W CGR1 ribosome biogenesis, rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism nucleolus ->
nucleus
YJR070C NO SYMBOL GAT3, YAP5
YLR222C UTP13 processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex ABF1
|YPR183W| DPM1 N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
lipid biosynthesis, biosynthesis, membrane lipid metabolism, protein metabolism, lipoprotein metabolism transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
cytoplasm, endomembrane system SWI5
|YPL106C| SSE1 protein folding ->
protein metabolism co-chaperone activity ->
co-chaperone activity cytoplasm ->
cytoplasm HSF1, MSN4
Main: cell organization and biogenesis (0.67) RNA binding (0.50) nucleus (0.60) ABF1 (0.17)
Score: 0.47 0.17 0.40 0.000
P-value: 4.417E-04 (rRNA processing) 6.066E-01 (RNA binding) 1.424E-02 (nucleolus) 6.376E-01 (USV1)

ALPHA2(1) AND ALPHA1'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YLR222C) OR SimExpr(other) : 5 1

EXPR: (0.146) ALPHA2 (P < 0.000) ALPHA1' (P < 0.000) mRRPE (P < 0.004) PAC (P < 0.028)

ORF SYMBOL P F C TF
YJL033W HCA4 35S primary transcript processing ->
rRNA processing ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleolus HIR2, USV1
YMR049C ERB1 rRNA processing ->
rRNA processing RTG3
YGL029W CGR1 ribosome biogenesis, rRNA processing ->
ribosome biogenesis, rRNA processing nucleolus ->
nucleolus
YJR070C NO SYMBOL GAT3, YAP5
YLR222C UTP13 processing of 20S pre-rRNA ->
rRNA processing snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleolus, ribonucleoprotein complex ABF1
|YPR183W| DPM1 N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
protein amino acid glycosylation, phosphoinositide biosynthesis, protein lipidation, phosphoinositide metabolism transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network SWI5
Main: rRNA processing (0.80) RNA binding (0.67) nucleolus (0.75) ABF1 (0.20)
Score: 0.60 0.33 0.50 0.000
P-value: 1.829E-04 (rRNA processing) 4.564E-01 (RNA binding) 7.182E-03 (nucleolus) 4.272E-01 (USV1)

ABF1(1) AND PAC(1) => SimExpr(YNR046W) OR SimExpr(other) : 12 3

ABF1(1) AND mRRPE(1) AND PAC(1) => SimExpr(YNR046W) OR SimExpr(other) : 9 1

EXPR: (0.132) ABF1 (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.002)

ORF SYMBOL P F C TF
YPR010C RPA135 transcription from Pol I promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DNA-directed RNA polymerase activity ->
DNA-directed RNA polymerase activity DNA-directed RNA polymerase I complex ->
nucleus ROX1, SIG1
YNL292W PUS4 tRNA modification ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism pseudouridylate synthase activity ->
pseudouridylate synthase activity mitochondrion, nucleus ->
cytoplasm, nucleus RCS1
YNL112W DBP2 RNA helicase activity ->
RNA helicase activity bud neck ->
site of polarized growth (sensu Fungi)
YKL014C NO SYMBOL ABF1
YKL172W EBP2 rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism nucleolus ->
nucleus ABF1, FZF1, RFX1
YLR197W SIK1 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex, nucleus, nucleolus ->
nucleus, ribonucleoprotein complex DAL81, HAL9
YGR187C HGH1 ABF1, HAP3, HIR1, RCS1, RTG1
YJL050W MTR4 35S primary transcript processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ATP dependent RNA helicase activity ->
RNA helicase activity, ATP dependent helicase activity, RNA dependent ATPase activity nucleolus ->
nucleus
|YJL069C| UTP18 ABF1
YNR046W NO SYMBOL ABF1
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (1.00) RNA helicase activity (0.50) nucleus (0.83) ABF1 (0.62)
Score: 1.00 0.17 0.67 0.393
P-value: 5.162E-03 (transcription from Pol I promoter) 4.041E-02 (RNA helicase activity) 2.661E-03 (nucleolus) 2.954E-03 (ABF1)

ALPHA2(1) AND RPN4(1) => SimExpr(YOL038W) OR SimExpr(other) : 7 2

EXPR: (0.179) ALPHA2 (P < 0.002) RPN4 (P < 0.490)

ALPHA2(1) AND SFF(1) AND RPN4(1) => SimExpr(YOL038W) : 6

EXPR: (0.151) ALPHA2 (P < 0.000) SFF (P < 0.000) RPN4 (P < 0.112)

RPN4(1) => SimExpr(YHR027C) OR SimExpr(other) : 35 17

ABF1(1) AND RPN4(1) => SimExpr(YHR027C) OR SimExpr(other) : 5 2

ABF1(1) AND PAC(1) => SimExpr(YKL172W) OR SimExpr(other) : 13 2

ABF1(1) AND mRRPE(1) AND PAC(1) => SimExpr(YKL172W) : 10

ABF1(1) AND ALPHA1'(1) AND PAC(1) => SimExpr(YKL014C) : 5

ABF1(1) AND STE12(1) => SimExpr(YFL008W) OR SimExpr(other) : 5 1

EXPR: (0.153) ABF1 (P < 0.001) STE12 (P < 0.000)

ORF SYMBOL P F C TF
YLR429W CRN1 actin filament organization, microtubule-based process ->
cytoplasm organization and biogenesis actin cross-linking activity, microtubule binding ->
protein binding actin cortical patch (sensu Saccharomyces) ->
cell cortex, cytoplasm
YDR303C RSC3 regulation of transcription\, DNA-dependent, regulation of cell cycle ->
cell cycle, transcription DNA binding ->
DNA binding RSC complex, nucleus ->
nucleus
YNL258C DSL1 retrograde (Golgi to ER) transport ->
secretory pathway, vesicle-mediated transport endoplasmic reticulum ->
cytoplasm ABF1, ARG80, HAP5, YJL206C
|YJL069C| UTP18 ABF1
YFL008W SMC1 mitotic chromosome segregation ->
cell cycle, mitotic cell cycle DNA secondary structure binding, AT DNA binding, double-stranded DNA binding, ATPase activity ->
DNA binding, double-stranded DNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nuclear cohesin complex ->
chromosome, nucleus MBP1
YKL022C CDC16 mitotic spindle elongation, ubiquitin-dependent protein catabolism, mitotic metaphase/anaphase transition, mitotic chromosome segregation, cyclin catabolism ->
cytoplasm organization and biogenesis, macromolecule catabolism, cell cycle, M phase, mitotic cell cycle, protein metabolism ubiquitin-protein ligase activity, protein binding ->
ligase activity\, forming carbon-nitrogen bonds, protein binding anaphase-promoting complex ->
nucleus, ubiquitin ligase complex AZF1
Main: cell cycle (0.60) protein binding (0.50) nucleus (0.60) ABF1 (0.50)
Score: 0.40 0.33 0.40 0.167
P-value: 1.792E-02 (mitotic chromosome segregation) 3.414E-01 (protein binding) 2.133E+00 (nucleus) 3.489E-01 (ABF1)

mRRPE(1) AND PAC(1) => SimExpr(YLR197W) OR SimExpr(other) : 60 16

LYS14(1) AND mRRPE(1) AND PAC(1) => SimExpr(YML093W) OR SimExpr(other) : 7 1

LYS14(1) AND mRRPE(1) AND PAC(1) => SimExpr(YHR052W) OR SimExpr(other) : 7 1

SFF'(1) AND SWI5(1) AND Yap1(1) => SimExpr(YOR173W) OR SimExpr(other) : 5 2

EXPR: (0.151) SFF' (P < 0.000) SWI5 (P < 0.000) Yap1 (P < 0.008)

ORF SYMBOL P F C TF
YPL091W GLR1 response to oxidative stress ->
response to oxidative stress glutathione reductase (NADPH) activity ->
glutathione reductase (NADPH) activity
YOR173W DCS2 CAD1
|YFL056C| AAD6 aldehyde metabolism ->
aldehyde metabolism benzyl alcohol dehydrogenase activity ->
benzyl alcohol dehydrogenase activity ACE2, YAP1
YFR014C CMK1 protein amino acid phosphorylation, signal transduction ->
protein amino acid phosphorylation, signal transduction calmodulin-dependent protein kinase I activity ->
calmodulin-dependent protein kinase I activity cytoplasm ->
cytoplasm USV1
YOL048C NO SYMBOL SKN7
YDR453C TSA2 regulation of redox homeostasis ->
regulation of redox homeostasis thioredoxin peroxidase activity ->
thioredoxin peroxidase activity nucleus ->
nucleus SWI4
|YPR005C| HAL1 salinity response, transcription initiation from Pol II promoter ->
salinity response, transcription initiation from Pol II promoter cytoplasm ->
cytoplasm CIN5
Main: signal transduction (0.20) calmodulin-dependent protein kinase I activity (0.25) cytoplasm (0.67) SWI4 (0.17)
Score: 0.00 0.00 0.33 0.000
P-value: 3.521E-01 (response to stress) 4.856E-02 (oxidoreductase activity) 4.860E+00 (cytoplasm) 4.959E-01 (USV1)

SFF(1) AND SWI5(1) AND Yap1(1) => SimExpr(YOR173W) OR SimExpr(other) : 5 2

EXPR: (0.151) SFF (P < 0.000) SWI5 (P < 0.000) Yap1 (P < 0.010)

ALPHA1'(1) AND BAS1(1) AND STE12(1) => SimExpr(YJL005W) OR SimExpr(other) : 5 2

EXPR: (0.186) ALPHA1' (P < 0.004) BAS1 (P < 0.024) STE12 (P < 0.005)

ORF SYMBOL P F C TF
YJL005W CYR1 meiosis, G-protein signaling\, coupled to cAMP nucleotide second messenger, RAS protein signal transduction, regulation of cell cycle ->
nuclear division, G-protein coupled receptor protein signaling pathway, RAS protein signal transduction, regulation of cell cycle, cyclic-nucleotide-mediated signaling adenylate cyclase activity ->
adenylate cyclase activity plasma membrane ->
plasma membrane
YMR019W STB4 DNA binding ->
DNA binding nucleus ->
nucleus PHD1, SKN7, SWI4
|YPR015C| NO SYMBOL
YLR328W NMA1 nicotinamide adenine dinucleotide metabolism ->
pyridine nucleotide metabolism nicotinamide-nucleotide adenylyltransferase activity ->
nicotinamide-nucleotide adenylyltransferase activity CIN5, MSN1, ROX1
YDR462W MRPL28 protein biosynthesis ->
protein biosynthesis structural constituent of ribosome ->
structural constituent of ribosome mitochondrial large ribosomal subunit ->
mitochondrial large ribosomal subunit ABF1
YMR148W NO SYMBOL
|YOR212W| STE4 signal transduction during conjugation with cellular fusion ->
G-protein coupled receptor protein signaling pathway, conjugation with cellular fusion, chemosensory perception heterotrimeric G-protein GTPase activity ->
heterotrimeric G-protein GTPase activity heterotrimeric G-protein complex, plasma membrane, shmoo tip ->
heterotrimeric G-protein complex, plasma membrane, shmoo tip
Main: G-protein coupled receptor protein signaling pathway (0.50) nicotinamide-nucleotide adenylyltransferase activity (0.20) plasma membrane (0.50) ABF1 (0.33)
Score: 0.17 0.00 0.17 0.000
P-value: 9.778E-03 (G-protein coupled receptor protein signaling pathway) 2.754E+00 (binding) 4.795E-01 (plasma membrane) 2.021E-01 (MSN1)

RPN4(1) => SimExpr(YFL056C) OR SimExpr(other) : 37 15

mRRPE(1) AND STE12(1) AND PAC(1) => SimExpr(YMR310C) : 5

AVERAGE SCORES:

P
  SCORE: 0.612 (Part of genes covered by "Main": 0.711) (No. rules=58/59)
  P-VALUE: 0.638
F
  SCORE: 0.263 (Part of genes covered by "Main": 0.508) (No. rules=57/59)
  P-VALUE: 0.386
C
  SCORE: 0.694 (Part of genes covered by "Main": 0.789) (No. rules=57/59)
  P-VALUE: 0.614
TF
  SCORE: 0.244 (Part of genes covered by "Main": 0.448) (No. rules=57/59)
  P-VALUE: 0.351
EXPRESSION: 0.729 (59)

ORF	SYMBOL	P	F	C	TF
\|YIL122W\|	POG1	re-entry into mitotic cell cycle after pheromone arrest -> cell growth and/or maintenance, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus	specific RNA polymerase II transcription factor activity -> specific RNA polymerase II transcription factor activity	nucleus -> nucleus	ASH1, CIN5, NRG1, RLM1, SMP1, YAP6
YOR310C	NOP58	rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription		small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	ABF1, SWI6
YJL148W	RPA34	transcription from Pol I promoter -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	DNA-directed RNA polymerase activity -> transferase activity\, transferring phosphorus-containing groups	DNA-directed RNA polymerase I complex, nucleus, nucleolus -> nucleus	AZF1, CHA4, CUP9, DAL81, DIG1, FZF1, GCR1, GCR2, GLN3, HAL9, HAP2, HAP3, HMS1, LEU3, MAC1, MBP1, MET31, MOT3, NDD1, PDR1, PHD1, REB1, RLM1, RME1, ROX1, RPH1, RTS2, SKN7, SWI5, YAP6, ZAP1
YGR245C	SDA1	actin cytoskeleton organization and biogenesis, start control point of mitotic cell cycle -> cell growth and/or maintenance		nucleus -> nucleus
YNL110C	NOP15	ribosomal large subunit biogenesis -> cell growth and/or maintenance		nucleus, nucleolus -> nucleus
YJL050W	MTR4	35S primary transcript processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ATP dependent RNA helicase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleolus -> nucleus
YDR399W	HPT1	purine nucleotide biosynthesis -> biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	hypoxanthine phosphoribosyltransferase activity -> transferase activity\, transferring glycosyl groups
YMR131C	RRB1	ribosome biogenesis -> cell growth and/or maintenance		nucleolus -> nucleus	FZF1, MATa1, RGT1
YAL059W	ECM1	cell wall organization and biogenesis -> cell growth and/or maintenance			MOT3
YLR197W	SIK1	rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription		small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex, nucleus, nucleolus -> nucleus, ribonucleoprotein complex	DAL81, HAL9
\|YPR183W\|	DPM1	N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis -> lipid biosynthesis, biosynthesis, membrane lipid metabolism, protein metabolism, lipoprotein metabolism	transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity -> transferase activity\, transferring glycosyl groups	endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network -> cytoplasm, endomembrane system	SWI5
YOR078W	BUD21	processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	ABF1, MSS11, SIG1, SKO1
YNL209W	SSB2	protein biosynthesis -> biosynthesis, protein metabolism	chaperone activity, ATPase activity -> chaperone activity, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	polysome, cytoplasm -> cytoplasm, ribonucleoprotein complex	ABF1, RFX1
YHR169W	DBP8	35S primary transcript processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ATP dependent RNA helicase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleolus -> nucleus
YOR272W	YTM1	chromosome organization and biogenesis (sensu Eukarya), ribosomal large subunit biogenesis -> cell growth and/or maintenance		nucleus, nucleolus -> nucleus	LEU3, PUT3, REB1
YMR229C	RRP5	rRNA processing, processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	RNA binding, snoRNA binding -> RNA binding	nucleolus, nucleolus organizer complex -> nucleus	FHL1, RAP1
\|YKL014C\|	NO SYMBOL				ABF1
YGR159C	NSR1	ribosomal small subunit assembly and maintenance, rRNA processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	single-stranded DNA binding, RNA binding -> DNA binding, RNA binding	nucleolus, nucleus -> nucleus
YLR249W	YEF3	translational elongation -> biosynthesis, protein metabolism	translation elongation factor activity -> translation factor activity\, nucleic acid binding	ribosome -> cytoplasm, ribonucleoprotein complex	INO2, INO4
YGR187C	HGH1				ABF1, HAP3, HIR1, RCS1, RTG1
YMR014W	BUD22	bud site selection -> cell growth and/or maintenance		nucleus -> nucleus	CUP9, HAL9, HIR2, LEU3, NDD1, RLM1, ROX1, SMP1, YAP6
YJR002W	MPP10	rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription		small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex, nucleolus, nucleus -> nucleus, ribonucleoprotein complex
YPR144C	NOC4	ribosome biogenesis -> cell growth and/or maintenance		nucleus -> nucleus	HIR1
YGR272C	NO SYMBOL				REB1, STP2
YFR001W	LOC1	ribosomal large subunit biogenesis -> cell growth and/or maintenance	mRNA binding -> RNA binding	nucleus -> nucleus	ARG80, GAL4, GTS1, HAP4, HIR1, LEU3, MSN2, MSN4, RCS1, RLM1, SWI4
YGL078C	DBP3	ribosomal large subunit assembly and maintenance, 35S primary transcript processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ATP dependent RNA helicase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleolus -> nucleus
YDR101C	ARX1	ribosomal large subunit biogenesis -> cell growth and/or maintenance		nucleoplasm, cytoplasm -> nucleus, cytoplasm	IXR1, RFX1
\|YML125C\|	NO SYMBOL				MAL13, MSN4, NDD1, RME1, SWI5
YPR010C	RPA135	transcription from Pol I promoter -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	DNA-directed RNA polymerase activity -> transferase activity\, transferring phosphorus-containing groups	DNA-directed RNA polymerase I complex -> nucleus	ROX1, SIG1
\|YJL069C\|	UTP18				ABF1
YGL029W	CGR1	ribosome biogenesis, rRNA processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism		nucleolus -> nucleus
YHR052W	CIC1	protein catabolism -> catabolism, protein metabolism	protein binding\, bridging -> protein binding\, bridging	nucleolus, proteasome complex (sensu Eukarya) -> nucleus, cytoplasm	HAP4, MATa1
\|YDR279W\|	RNH202				GCR2, MBP1, RIM101, RLM1, SWI6, THI2
YMR310C	NO SYMBOL
YNR046W	NO SYMBOL				ABF1
\|YNL292W\|	PUS4	tRNA modification -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	pseudouridylate synthase activity -> carbon-oxygen lyase activity	mitochondrion, nucleus -> cytoplasm, nucleus	RCS1
YNR024W	NO SYMBOL
\|YMR259C\|	NO SYMBOL				ARG80, GCR2, GTS1, HIR1, SRD1
YHR196W	UTP9	processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex, nucleolus, nucleus -> nucleus, ribonucleoprotein complex
YNR053C	NOG2	mRNA splicing -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	GTPase activity -> purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleus, nucleolus, nucleoplasm -> nucleus, nucleoplasm	ABF1, AZF1
YGR145W	ENP2
YGL171W	ROK1	35S primary transcript processing, mRNA splicing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ATP dependent RNA helicase activity, ATPase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleolus -> nucleus	RGT1
\|YGL016W\|	KAP122	protein-nucleus import, response to drug -> response to abiotic stimulus, protein metabolism, cell growth and/or maintenance	protein carrier activity -> protein carrier activity	cytoplasm, nuclear pore -> cytoplasm, nucleus, integral to membrane, endomembrane system	MSN2
YLR276C	DBP9	ribosomal large subunit assembly and maintenance, 35S primary transcript processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ATP dependent RNA helicase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleolus -> nucleus	MATa1, RCS1, RTG3, SWI5
YKL172W	EBP2	rRNA processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism		nucleolus -> nucleus	ABF1, FZF1, RFX1
YDR449C	UTP6	processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	FHL1, GAT3, HIR2, RAP1, RGM1, YAP5
YPL043W	NOP4	rRNA processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	RNA binding -> RNA binding	nucleolus -> nucleus
YKL056C	NO SYMBOL
YGR162W	TIF4631	translational initiation -> biosynthesis, protein metabolism	translation initiation factor activity -> translation factor activity\, nucleic acid binding	ribosome -> cytoplasm, ribonucleoprotein complex	HSF1
YGL169W	SUA5	cell growth and/or maintenance -> cell growth and/or maintenance			ABF1
YML093W	UTP14	processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex
YPL266W	DIM1	rRNA modification, 35S primary transcript processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription	rRNA (adenine-N6\,N6-)-dimethyltransferase activity -> transferase activity\, transferring one-carbon groups	nucleolus -> nucleus	ARG81, STP2
\|YOR381W\|	FRE3	iron-siderochrome transport, iron ion homeostasis -> cell growth and/or maintenance	ferric-chelate reductase activity -> oxidoreductase activity\, oxidizing metal ions	plasma membrane, integral to membrane -> plasma membrane, integral to membrane	CIN5, PDR1, YAP6
YJL109C	UTP10	processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex
YDR161W	NO SYMBOL
YMR239C	RNT1	35S primary transcript processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ribonuclease III activity -> hydrolase activity\, acting on ester bonds, RNA binding	nucleolus -> nucleus
YJL033W	HCA4	35S primary transcript processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ATP dependent RNA helicase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleolus -> nucleus	HIR2, USV1
YGL099W	LSG1	conjugation with cellular fusion, sporulation (sensu Saccharomyces), ribosome nucleus export -> conjugation, protein metabolism, cell growth and/or maintenance, sexual reproduction	GTPase activity -> purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	cytoplasm -> cytoplasm	PHO4
\|YJL138C\|	TIF2	translational initiation, regulation of translational initiation -> biosynthesis, protein metabolism	translation initiation factor activity, RNA helicase activity -> translation factor activity\, nucleic acid binding, RNA binding	ribosome, cytoplasm -> cytoplasm, ribonucleoprotein complex	PHD1
YNL075W	IMP4	rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription	rRNA primary transcript binding -> RNA binding	small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	USV1
YNL175C	NOP13		RNA binding -> RNA binding	nucleolus, nucleoplasm -> nucleus	INO2, INO4
YOL022C	NO SYMBOL				MAC1, MOT3, RTS2
\|YMR049C\|	ERB1	rRNA processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism			RTG3
YDR496C	PUF6				RFX1
YNL112W	DBP2		RNA helicase activity -> RNA binding	bud neck -> site of polarized growth (sensu Fungi)
YNL308C	KRI1	ribosome biogenesis -> cell growth and/or maintenance		nucleolus -> nucleus
YBR247C	ENP1	processing of 20S pre-rRNA, rRNA processing, cell growth and/or maintenance -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	nucleolus, nucleus -> nucleus
YDR365C	NO SYMBOL				ABF1, MSS11, YJL206C
YJR070C	NO SYMBOL				GAT3, YAP5
YLR222C	UTP13	processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	ABF1
YOR095C	RKI1	pentose-phosphate shunt -> coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism	ribose-5-phosphate isomerase activity -> intramolecular isomerase activity		FHL1, FKH2, RAP1
\|YOR359W\|	VTS1	protein-vacuolar targeting -> protein metabolism, cell growth and/or maintenance	intracellular transporter activity -> intracellular transporter activity	cytosol -> cytoplasm	RAP1
YNL132W	KRE33
YMR290C	HAS1			nucleolus, nuclear membrane -> nucleus, endomembrane system	RAP1
YGR280C	PXR1	35S primary transcript processing, snRNA processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	RNA binding -> RNA binding	nucleolus -> nucleus
YDR184C	ATC1	response to stress, polar budding -> response to stress, asexual reproduction		nucleus -> nucleus	ARO80, GLN3, SIP4, SKO1
Main:		cell growth and/or maintenance (0.76)	RNA binding (0.57)	nucleus (0.83)	ABF1 (0.23)
Score:		0.70	0.36	0.75	0.114
P-value:		5.177E-29 (ribosome biogenesis)	2.275E-08 (snoRNA binding)	2.137E-32 (nucleolus)	3.563E-01 (ABF1)

ORF	SYMBOL	P	F	C	TF
YGL147C	RPL9A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytosol, ribosome	FHL1, MBP1, RAP1, SWI4
\|YKL033W\|	NO SYMBOL				RPH1
YGL030W	RPL30	protein biosynthesis, rRNA processing, mRNA splicing, regulation of translation -> cell organization and biogenesis, biosynthesis, transcription, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya), cytoplasm -> cytosol, cytoplasm, ribosome	FHL1, GAT3, RAP1, SFP1
YGR214W	RPS0A	protein biosynthesis, ribosomal small subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> cytosol, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome	FHL1, RAP1
YGR085C	RPL11B	protein biosynthesis, ribosomal large subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytosol, ribosome	FHL1, MIG1
YMR230W	RPS10B	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> cytosol, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome	FHL1, RAP1
YDL130W	RPP1B	protein biosynthesis, translational elongation -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytosol, ribosome	FHL1, GAL4, RAP1, RFX1
YIL018W	RPL2B	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytosol, ribosome	FHL1, GAT3, PDR1, RAP1, RGM1, SWI5, YAP5
\|YGR254W\|	ENO1	gluconeogenesis, glycolysis -> alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism	phosphopyruvate hydratase activity -> phosphopyruvate hydratase activity	phosphopyruvate hydratase complex, cytoplasm -> cytosol, cytoplasm	FKH2, MSN4, PDR1, SWI5, YAP5
\|YKL152C\|	GPM1	gluconeogenesis, glycolysis -> alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism	phosphoglycerate mutase activity -> phosphoglycerate mutase activity	cytosol -> cytosol	GCR1, GCR2, HSF1, RAP1
YKL006W	RPL14A	protein biosynthesis -> biosynthesis, protein metabolism	RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytosol, ribosome	FHL1, GAT3, GRF10(Pho2), GTS1, RAP1
YML073C	RPL6A	protein biosynthesis, ribosomal large subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism	RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytosol, ribosome	FHL1, GAT3, RAP1, YAP5
YNL069C	RPL16B	protein biosynthesis -> biosynthesis, protein metabolism	RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytosol, ribosome	FHL1, GAT3, PDR1, RAP1, RGM1, YAP5
YOL120C	RPL18A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytosol, ribosome	FHL1, MAL13, RAP1, YAP5
\|YPL180W\|	BIT89	glycerol metabolism -> alcohol metabolism, glycerol ether metabolism, lipid metabolism			REB1, RGT1, SIG1
YDR450W	RPS18A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> cytosol, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome	FHL1, GAT3, HIR2, RAP1, RGM1, YAP5
YLR344W	RPL26A	protein biosynthesis -> biosynthesis, protein metabolism	RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytosol, ribosome	FHL1, RAP1
\|YLR452C\|	SST2	signal transduction, adaptation to pheromone during conjugation with cellular fusion -> signal transduction, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus	GTPase activator activity -> GTPase activator activity	plasma membrane -> plasma membrane	DIG1, FHL1, RAP1, STE12
YPL090C	RPS6A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> cytosol, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome	FHL1, GAT3, INO4, RAP1, YAP5
\|YJR139C\|	HOM6	homoserine biosynthesis, methionine metabolism, threonine metabolism -> amine metabolism, sulfur metabolism, biosynthesis, amino acid and derivative metabolism, organic acid metabolism	homoserine dehydrogenase activity -> homoserine dehydrogenase activity		HMS1, RAP1
YMR142C	RPL13B	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytosol, ribosome	FHL1, GAT3, RAP1, RGM1, YAP5
Main:		biosynthesis (0.90)	structural constituent of ribosome (0.79)	cytosol (0.94)	RAP1 (0.81)
Score:		0.82	0.61	0.89	0.752
P-value:		5.067E-09 (protein biosynthesis)	6.126E-14 (structural constituent of ribosome)	8.148E-16 (cytosolic ribosome (sensu Eukarya))	3.243E-20 (FHL1)

ORF	SYMBOL	P	F	C	TF
\|YJL079C\|	PRY1			nuclear membrane, endoplasmic reticulum -> nuclear membrane, endoplasmic reticulum	NDD1, PHD1, RAP1
YJL082W	IML2
YLR201C	NO SYMBOL				ABF1
YMR291W	NO SYMBOL				RAP1
YKL035W	UGP1	protein amino acid glycosylation, UDP-glucose metabolism -> protein amino acid glycosylation, UDP-glucose metabolism	UTP-glucose-1-phosphate uridylyltransferase activity -> UTP-glucose-1-phosphate uridylyltransferase activity
YOL087C	NO SYMBOL				DAL82
Main:		protein amino acid glycosylation (1.00)	UTP-glucose-1-phosphate uridylyltransferase activity (1.00)	endoplasmic reticulum (1.00)	RAP1 (0.50)
Score:		0.00	0.00	0.00	0.167
P-value:		0.000E+00	0.000E+00	0.000E+00	2.350E-01 (RAP1)

ORF	SYMBOL	P	F	C	TF
YML117W	NAB6
YOR299W	BUD7	bud site selection -> cell proliferation, cell organization and biogenesis			HSF1, MTH1
YOR185C	GSP2	nuclear organization and biogenesis -> cell organization and biogenesis	RAN small monomeric GTPase activity -> RAN small monomeric GTPase activity	nucleus -> nucleus
YFL004W	VTC2	protein localization, vacuole fusion (non-autophagic) -> protein metabolism, cell organization and biogenesis		vacuolar membrane -> cytoplasm	CIN5, GCN4, STE12, YAP1, YAP6
YJL042W	MHP1	microtubule stabilization, cell wall organization and biogenesis -> cell organization and biogenesis	structural constituent of cytoskeleton -> structural constituent of cytoskeleton	microtubule -> cytoplasm	CRZ1, GAL4, GAT3, PDR1, RGM1, YAP5
\|YPL190C\|	NAB3	regulation of transcription from Pol II promoter -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	poly(A) binding -> poly(A) binding	nucleoplasm -> nucleus	RFX1
Main:		cell organization and biogenesis (0.80)	poly(A) binding (0.33)	cytoplasm (0.50)	MTH1 (0.25)
Score:		0.60	0.00	0.33	0.000
P-value:		3.488E-01 (organelle organization and biogenesis)	1.794E+00 (binding)	4.104E+00 (nucleus)	5.520E-01 (GAL4)

ORF	SYMBOL	P	F	C	TF
YGR158C	MTR3	35S primary transcript processing, mRNA catabolism -> ribosome biogenesis, mRNA catabolism, RNA processing, transcription from Pol I promoter	3'-5' exoribonuclease activity -> hydrolase activity\, acting on ester bonds, RNA binding	nuclear exosome (RNase complex), cytoplasmic exosome (RNase complex) -> exosome (RNase complex), cytoplasm, nucleus	ZMS1
\|YKL142W\|	MRP8	protein biosynthesis -> protein biosynthesis	structural constituent of ribosome -> structural constituent of ribosome	mitochondrial ribosome -> cytoplasm, ribonucleoprotein complex	ACE2, CIN5, MBP1, PHO4, REB1, SKN7, STB1
YGR251W	NO SYMBOL				MSN4, PHD1, SKN7
YJL069C	UTP18				ABF1
YPR137W	RRP9	rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> RNA modification, ribosome biogenesis, rRNA metabolism, RNA processing, transcription from Pol I promoter	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	ABF1, HIR1, RCS1
YNL308C	KRI1	ribosome biogenesis -> ribosome biogenesis		nucleolus -> nucleus
Main:		ribosome biogenesis (0.75)	RNA binding (0.67)	nucleus (0.75)	ABF1 SKN7 (0.40)
Score:		0.50	0.33	0.83	0.200
P-value:		2.288E-02 (ribosome biogenesis)	3.804E-01 (RNA binding)	1.782E-01 (nucleolus)	2.309E-01 (SKN7)

ORF	SYMBOL	P	F	C	TF
YLR455W	NO SYMBOL
YMR121C	RPL15B	protein biosynthesis -> biosynthesis, protein metabolism	RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	REB1
YOL148C	SPT20	chromatin modification, histone acetylation -> cell organization and biogenesis, protein metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	protein binding -> protein binding	SAGA complex -> nucleus	GRF10(Pho2), MATa1, MIG1, PHO4
YKR048C	NAP1	nucleosome assembly, M phase of mitotic cell cycle -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, cell proliferation	protein binding -> protein binding	nucleus -> nucleus	SKN7
YDR073W	SNF11	chromatin modeling -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	general RNA polymerase II transcription factor activity -> general RNA polymerase II transcription factor activity	nucleosome remodeling complex, SWI/SNF complex -> nucleus	DAL81, RLM1
YOR152C	NO SYMBOL				HIR2
\|YGR147C\|	NAT2	N-terminal peptidyl-methionine acetylation -> protein metabolism, protein modification	peptide alpha-N-acetyltransferase activity -> peptide alpha-N-acetyltransferase activity	cytoplasm -> cytoplasm	HIR1, REB1
\|YGL097W\|	SRM1	rRNA-nucleus export, ribosome nucleus export -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism, transport	signal transducer activity -> signal transducer activity	nucleus -> nucleus
YIL112W	HOS4	negative regulation of meiosis, histone deacetylation -> cell proliferation, cell organization and biogenesis, protein metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	NAD-dependent histone deacetylase activity, NAD-independent histone deacetylase activity -> NAD-dependent histone deacetylase activity, NAD-independent histone deacetylase activity	histone deacetylase complex -> nucleus	MAC1, REB1, YFL044C
\|YKR011C\|	NO SYMBOL				SWI4, SWI6
YGL237C	HAP2	transcription, regulation of carbohydrate metabolism -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, carbohydrate metabolism, energy pathways, regulation of metabolism	transcriptional activator activity -> transcriptional activator activity	nucleus, CCAAT-binding factor complex -> nucleus	REB1
\|YDL232W\|	OST4	N-linked glycosylation -> biosynthesis, protein metabolism	dolichyl-diphospho-oligosaccharide-protein glycosyltransferase activity, protein binding -> dolichyl-diphospho-oligosaccharide-protein glycosyltransferase activity, protein binding	endoplasmic reticulum membrane -> cytoplasm, endomembrane system	REB1
YGR012W	NO SYMBOL				MIG1, REB1
Main:		nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.67)	protein binding (0.33)	nucleus (0.67)	REB1 (0.55)
Score:		0.75	0.08	0.50	0.291
P-value:		1.495E-02 (DNA packaging)	2.960E-01 (protein binding)	4.345E-02 (transcription factor complex)	5.257E-05 (REB1)

ORF	SYMBOL	P	F	C	TF
YGR283C	NO SYMBOL				ACE2, RAP1, SMP1
YPR010C	RPA135	transcription from Pol I promoter -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	DNA-directed RNA polymerase activity -> transferase activity\, transferring phosphorus-containing groups	DNA-directed RNA polymerase I complex -> nucleus	ROX1, SIG1
YNL292W	PUS4	tRNA modification -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	pseudouridylate synthase activity -> carbon-oxygen lyase activity	mitochondrion, nucleus -> cytoplasm, nucleus	RCS1
YNL112W	DBP2		RNA helicase activity -> RNA binding	bud neck -> site of polarized growth (sensu Fungi)
YKL014C	NO SYMBOL				ABF1
YKL172W	EBP2	rRNA processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism		nucleolus -> nucleus	ABF1, FZF1, RFX1
YLR197W	SIK1	rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription		small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex, nucleus, nucleolus -> nucleus, ribonucleoprotein complex	DAL81, HAL9
YGR187C	HGH1				ABF1, HAP3, HIR1, RCS1, RTG1
YKL078W	DHR2	ribosome biogenesis -> cell organization and biogenesis	RNA helicase activity -> RNA binding	nucleolus -> nucleus	ABF1
YOL041C	NOP12	rRNA metabolism -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	RNA binding -> RNA binding	nucleolus -> nucleus	GTS1, MET31
\|YHR027C\|	RPN1	ubiquitin-dependent protein catabolism -> catabolism, protein metabolism	endopeptidase activity, receptor activity -> peptidase activity, receptor activity	proteasome regulatory particle (sensu Eukarya), endoplasmic reticulum, cytoplasm -> cytoplasm, nucleus
YJL050W	MTR4	35S primary transcript processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ATP dependent RNA helicase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleolus -> nucleus
\|YJL069C\|	UTP18				ABF1
YNR046W	NO SYMBOL				ABF1
\|YDR527W\|	NO SYMBOL				ABF1, SKN7
Main:		nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.75)	RNA binding (0.57)	nucleus (0.89)	ABF1 (0.58)
Score:		0.64	0.29	0.78	0.333
P-value:		3.084E-02 (transcription from Pol I promoter)	4.360E-03 (RNA helicase activity)	9.555E-05 (nucleolus)	4.241E-04 (ABF1)

ORF	SYMBOL	P	F	C	TF
YFR020W	NO SYMBOL				MIG1
\|YNL251C\|	NRD1	nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	RNA binding -> RNA binding	nucleus -> nucleus	ABF1, MAC1
YJR006W	HYS2	leading strand elongation, lagging strand elongation, mutagenesis, base-excision repair, nucleotide-excision repair, postreplication repair, mismatch repair -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, DNA repair, cell proliferation	delta DNA polymerase activity -> delta DNA polymerase activity	delta DNA polymerase complex -> cytoplasm, nucleus	ABF1
YHR027C	RPN1	ubiquitin-dependent protein catabolism -> catabolism, protein metabolism	endopeptidase activity, receptor activity -> endopeptidase activity, receptor activity	proteasome regulatory particle (sensu Eukarya), endoplasmic reticulum, cytoplasm -> cytoplasm, nucleus
YGR253C	PUP2	ubiquitin-dependent protein catabolism, response to stress, sporulation (sensu Saccharomyces) -> catabolism, response to stress, sporulation, protein metabolism	endopeptidase activity -> endopeptidase activity	proteasome core complex (sensu Eukarya) -> cytoplasm, nucleus	ABF1, HIR2, PHO4
YHL024W	RIM4	sporulation, meiosis, premeiotic DNA synthesis, meiotic recombination -> sporulation, M phase, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, cell proliferation	RNA binding -> RNA binding	cytoplasm -> cytoplasm	FKH2, PHD1
YOR362C	PRE10	ubiquitin-dependent protein catabolism -> catabolism, protein metabolism	endopeptidase activity -> endopeptidase activity	proteasome core complex (sensu Eukarya) -> cytoplasm, nucleus
Main:		nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.50)	endopeptidase activity (0.50)	cytoplasm (0.83)	ABF1 (0.60)
Score:		0.47	0.27	0.93	0.300
P-value:		1.746E-02 (ubiquitin-dependent protein catabolism)	7.474E-04 (endopeptidase activity)	6.518E-04 (proteasome complex (sensu Eukarya))	6.278E-02 (ABF1)

ORF	SYMBOL	P	F	C	TF
YDL195W	SEC31	ER to Golgi transport -> transport, vesicle-mediated transport	structural molecule activity -> structural molecule activity	COPII vesicle coat -> cytoplasm	ABF1, GAT1, MTH1, SFL1, SIG1
YLR429W	CRN1	actin filament organization, microtubule-based process -> cell organization and biogenesis	actin cross-linking activity, microtubule binding -> actin cross-linking activity, microtubule binding	actin cortical patch (sensu Saccharomyces) -> cell cortex, cytoplasm
\|YJL097W\|	NO SYMBOL				ARG80, HAP3
\|YNL111C\|	CYB5	sterol biosynthesis -> alcohol metabolism, biosynthesis, lipid metabolism	electron transporter activity -> electron transporter activity	microsome -> membrane fraction	ABF1, GCR2, GTS1, NRG1, REB1, ROX1
YKR046C	PET10			lipid particle -> cytoplasm	ABF1
YGL207W	SPT16	chromatin modeling, regulation of global transcription from Pol II promoter, RNA elongation from Pol II promoter -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, DNA metabolism	transcriptional elongation regulator activity -> transcriptional elongation regulator activity	alpha DNA polymerase\:primase complex, nuclear chromatin, transcription elongation factor complex -> nucleus, chromosome	RTG1
\|YKL172W\|	EBP2	rRNA processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism		nucleolus -> nucleus	ABF1, FZF1, RFX1
YAL016W	TPD3	protein biosynthesis, actin filament organization, mitotic spindle checkpoint, bud growth, protein amino acid dephosphorylation -> biosynthesis, cell organization and biogenesis, asexual reproduction, phosphorus metabolism, cell proliferation, cell cycle, protein metabolism	protein phosphatase type 2A activity -> protein phosphatase type 2A activity	protein phosphatase type 2A complex, bud neck, nucleus, cytoplasm, shmoo tip, bud tip, spindle pole body -> protein phosphatase type 2A complex, nucleus, site of polarized growth (sensu Fungi), site of polarized growth (sensu Saccharomyces), cytoplasm, microtubule organizing center	ABF1
YJL091C	GWT1	GPI anchor biosynthesis -> biosynthesis, membrane lipid metabolism, protein metabolism, lipid metabolism		membrane -> membrane
YHR027C	RPN1	ubiquitin-dependent protein catabolism -> catabolism, protein metabolism	endopeptidase activity, receptor activity -> endopeptidase activity, receptor activity	proteasome regulatory particle (sensu Eukarya), endoplasmic reticulum, cytoplasm -> cytoplasm, nucleus
YKR084C	HBS1	protein biosynthesis -> biosynthesis, protein metabolism			PHO4
\|YNR046W\|	NO SYMBOL				ABF1
YNL059C	ARP5	protein-vacuolar targeting -> cell organization and biogenesis, protein metabolism, transport		nucleus -> nucleus	ABF1, GRF10(Pho2)
Main:		cell organization and biogenesis (0.50)	electron transporter activity (0.17)	cytoplasm (0.50)	ABF1 (0.70)
Score:		0.51	0.00	0.42	0.467
P-value:		3.890E-01 (actin filament organization)	2.991E+00 (hydrolase activity)	1.171E+00 (cytoskeleton)	1.272E-04 (ABF1)

ORF	SYMBOL	P	F	C	TF
YDL003W	MCD1	mitotic sister chromatid cohesion, mitotic chromosome condensation -> cell proliferation, cell cycle		nuclear cohesin complex -> chromosome, nucleus	CIN5, MBP1, SWI6
YPR185W	APG13	protein-vacuolar targeting, autophagy -> cell organization and biogenesis, autophagy, protein metabolism, transport	protein binding -> protein binding	extrinsic to membrane -> extrinsic to membrane	MET4, SWI6
YLR212C	TUB4	microtubule nucleation, mitotic spindle assembly (sensu Saccharomyces) -> cell organization and biogenesis, cell proliferation, cell cycle	structural constituent of cytoskeleton -> structural constituent of cytoskeleton	inner plaque of spindle pole body, outer plaque of spindle pole body -> cytoplasm
YPL123C	RNY1	cellular morphogenesis -> cell organization and biogenesis	endoribonuclease activity -> hydrolase activity\, acting on ester bonds, RNA binding	extracellular -> extracellular	ARG80, CUP9, DAL81, FZF1, NRG1, STB1
YJR006W	HYS2	leading strand elongation, lagging strand elongation, mutagenesis, base-excision repair, nucleotide-excision repair, postreplication repair, mismatch repair -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, DNA repair, cell proliferation	delta DNA polymerase activity -> transferase activity\, transferring phosphorus-containing groups	delta DNA polymerase complex -> cytoplasm, nucleus	ABF1
\|YNL102W\|	POL1	DNA replication\, priming, DNA replication initiation, lagging strand elongation, DNA repair synthesis -> DNA metabolism, cell proliferation	alpha DNA polymerase activity -> transferase activity\, transferring phosphorus-containing groups	alpha DNA polymerase\:primase complex -> nucleus	LEU3, MBP1
YLR430W	SEN1	35S primary transcript processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ATP dependent RNA helicase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleolus -> nucleus	ARG80, GTS1, HAP5, RTG3, SIP4
\|YMR102C\|	NO SYMBOL
Main:		cell organization and biogenesis (0.57)	RNA binding (0.33)	nucleus (0.57)	ARG80 MBP1 SWI6 (0.33)
Score:		0.62	0.13	0.33	0.200
P-value:		3.346E-03 (lagging strand elongation)	1.223E-02 (DNA-directed DNA polymerase activity)	1.056E-02 (replication fork)	1.376E-01 (ARG80)

ORF	SYMBOL	P	F	C	TF
YJR019C	TES1	fatty acid oxidation -> lipid metabolism, carboxylic acid metabolism	acyl-CoA thioesterase activity -> acyl-CoA thioesterase activity	peroxisome -> cytoplasm	DAL82, MTH1
YLR174W	IDP2	isocitrate metabolism, glutamate biosynthesis -> carbohydrate metabolism, amine biosynthesis, amine metabolism, carboxylic acid metabolism, energy derivation by oxidation of organic compounds, amino acid and derivative metabolism	isocitrate dehydrogenase (NADP+) activity -> isocitrate dehydrogenase (NADP+) activity	cytosol -> cytoplasm	ABF1, CBF1, RAP1
YMR135C	GID8	negative regulation of gluconeogenesis -> alcohol biosynthesis, regulation of biosynthesis, monosaccharide metabolism, carbohydrate metabolism, negative regulation of metabolism, carbohydrate biosynthesis, energy derivation by oxidation of organic compounds, regulation of metabolism			ASH1, CUP9, DAL81, INO4, NDD1, NRG1, PHD1, ROX1, SKN7, SWI4, YAP6
\|YDR134C\|	NO SYMBOL				ASH1, NRG1, SOK2, SWI4
YNL329C	PEX6	peroxisome organization and biogenesis -> cytoplasm organization and biogenesis	ATPase activity -> ATPase activity	peroxisome -> cytoplasm	RAP1
YML042W	CAT2	carnitine metabolism -> amine metabolism, carboxylic acid metabolism, water-soluble vitamin metabolism, amino acid derivative metabolism	carnitine O-acetyltransferase activity -> carnitine O-acetyltransferase activity	peroxisomal matrix, mitochondrion, peroxisome -> cytoplasm	MAL13
Main:		carboxylic acid metabolism (0.60)	ATPase activity (0.25)	cytoplasm (1.00)	SWI4 RAP1 ASH1 NRG1 (0.33)
Score:		0.40	0.00	1.00	0.133
P-value:		4.936E-02 (organic acid metabolism)	1.308E+00 (hydrolase activity)	2.629E-04 (peroxisome)	2.324E-02 (ASH1)

ORF	SYMBOL	P	F	C	TF
YMR194W	RPL36A	protein biosynthesis -> biosynthesis, protein metabolism	RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	ARG80, ARO80, BAS1, CUP9, FHL1, HAL9, HAP4, HAP5, HMS1, MET31, NRG1, RAP1, RCS1, RME1, STP2
\|YOL160W\|	NO SYMBOL				ARO80, NRG1, PHO4, RLM1, SIP4, SWI6
YNL024C	NO SYMBOL				GRF10(Pho2)
YGR085C	RPL11B	protein biosynthesis, ribosomal large subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, MIG1
\|YPL189W\|	GUP2			membrane -> membrane	RFX1
YPL131W	RPL5	protein biosynthesis, ribosomal large subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism	RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, GAT3, RAP1
YLR344W	RPL26A	protein biosynthesis -> biosynthesis, protein metabolism	RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, RAP1
YLR249W	YEF3	translational elongation -> biosynthesis, protein metabolism	translation elongation factor activity -> translation elongation factor activity	ribosome -> cytoplasm, ribonucleoprotein complex	INO2, INO4
YGR260W	TNA1	nicotinamide mononucleotide transport -> transport	nicotinamide mononucleotide permease activity -> nicotinamide mononucleotide permease activity	integral to plasma membrane -> membrane	HIR2, SUM1
YPR080W	TEF1	translational elongation -> biosynthesis, protein metabolism	translation elongation factor activity -> translation elongation factor activity	ribosome -> cytoplasm, ribonucleoprotein complex	FHL1, PDR1, RAP1, YAP5
YOR369C	RPS12	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	ARG80, FHL1, FKH2, LEU3, NDD1, PDR1, RME1, SMP1, YAP6
YLR208W	SEC13	nonselective vesicle assembly, ER to Golgi transport, ER-associated protein catabolism -> macromolecule catabolism, transport, protein metabolism		cytoplasm, COPII vesicle coat, nuclear pore, extrinsic to plasma membrane -> nucleus, cytoplasm, membrane coat, membrane
Main:		protein metabolism (0.89)	structural constituent of ribosome (0.62)	cytoplasm (0.80)	FHL1 (0.55)
Score:		0.81	0.39	0.69	0.291
P-value:		2.067E-03 (protein biosynthesis)	4.393E-03 (structural constituent of ribosome)	1.274E-04 (ribosome)	1.492E-05 (FHL1)

ORF	SYMBOL	P	F	C	TF
\|YOR213C\|	SAS5	chromatin silencing at telomere -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription	acetyltransferase activity -> transferase activity\, transferring groups other than amino-acyl groups	nuclear chromosome\, telomeric region, nuclear chromatin -> chromosome, nuclear chromosome	GRF10(Pho2), SUM1
YMR194W	RPL36A	protein biosynthesis -> biosynthesis, protein metabolism	RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	ARG80, ARO80, BAS1, CUP9, FHL1, HAL9, HAP4, HAP5, HMS1, MET31, NRG1, RAP1, RCS1, RME1, STP2
\|YMR013C\|	SEC59	protein-ER targeting, protein amino acid glycosylation -> cell organization and biogenesis, biosynthesis, protein modification, protein metabolism, transport	dolichol kinase activity -> phosphotransferase activity\, alcohol group as acceptor	membrane -> membrane	FHL1, NDD1, RAP1, RLM1, RME1
YKR092C	SRP40	nucleocytoplasmic transport -> transport	chaperone activity -> chaperone activity	nucleolus -> nucleus	CUP9, MET4, RAP1
YLR441C	RPS1A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	FHL1, GAT3, RAP1, YAP5
YMR224C	MRE11	DNA repair, double-strand break repair via nonhomologous end-joining, meiotic DNA double-strand break formation, meiotic DNA double-strand break processing, double-strand break repair via break-induced replication -> DNA metabolism, cell proliferation, catabolism	endonuclease activity, 3'-5' exonuclease activity, protein binding -> nuclease activity, protein binding	nucleus -> nucleus	RAP1
YDR450W	RPS18A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	FHL1, GAT3, HIR2, RAP1, RGM1, YAP5
\|YGL196W\|	NO SYMBOL
YGL030W	RPL30	protein biosynthesis, rRNA processing, mRNA splicing, regulation of translation -> cell organization and biogenesis, biosynthesis, transcription, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya), cytoplasm -> cytoplasm, ribonucleoprotein complex	FHL1, GAT3, RAP1, SFP1
\|YNL311C\|	NO SYMBOL				GCN4, RAP1
YNL069C	RPL16B	protein biosynthesis -> biosynthesis, protein metabolism	RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, GAT3, PDR1, RAP1, RGM1, YAP5
YLR344W	RPL26A	protein biosynthesis -> biosynthesis, protein metabolism	RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, RAP1
YOR312C	RPL20B	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, FKH2, GAT3, RAP1
YJR145C	RPS4A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya), cytoplasm -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	ACE2, CIN5, FHL1, INO4, MTH1, RAP1, YAP6
YLR249W	YEF3	translational elongation -> biosynthesis, protein metabolism	translation elongation factor activity -> translation elongation factor activity	ribosome -> cytoplasm, ribonucleoprotein complex	INO2, INO4
\|YGL115W\|	SNF4	regulation of transcription from Pol II promoter, peroxisome organization and biogenesis -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	protein kinase activator activity -> protein kinase activator activity	plasma membrane, nucleus, cytoplasm -> membrane, nucleus, cytoplasm	BAS1, CAD1, MAC1, NRG1, PDR1, RAP1, SMP1, YAP5
\|YJL217W\|	NO SYMBOL				CIN5, MAC1, PHD1, SWI5, YAP6
YOL120C	RPL18A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, MAL13, RAP1, YAP5
YPR080W	TEF1	translational elongation -> biosynthesis, protein metabolism	translation elongation factor activity -> translation elongation factor activity	ribosome -> cytoplasm, ribonucleoprotein complex	FHL1, PDR1, RAP1, YAP5
YLR452C	SST2	signal transduction, adaptation to pheromone during conjugation with cellular fusion -> signal transduction, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus	GTPase activator activity -> GTPase activator activity	plasma membrane -> membrane	DIG1, FHL1, RAP1, STE12
YOR369C	RPS12	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	ARG80, FHL1, FKH2, LEU3, NDD1, PDR1, RME1, SMP1, YAP6
\|YPR161C\|	SGV1	transcription, protein amino acid phosphorylation -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, phosphorus metabolism, protein metabolism	cyclin-dependent protein kinase activity -> phosphotransferase activity\, alcohol group as acceptor	nucleus -> nucleus	RAP1
YKL006W	RPL14A	protein biosynthesis -> biosynthesis, protein metabolism	RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, GAT3, GRF10(Pho2), GTS1, RAP1
Main:		protein metabolism (0.75)	structural constituent of ribosome (0.55)	cytoplasm (0.70)	RAP1 (0.82)
Score:		0.59	0.30	0.53	0.745
P-value:		3.312E-07 (protein biosynthesis)	3.091E-07 (structural constituent of ribosome)	1.091E-08 (cytosolic ribosome (sensu Eukarya))	5.425E-17 (RAP1)

ORF	SYMBOL	P	F	C	TF
YGR135W	PRE9	ubiquitin-dependent protein catabolism -> catabolism, protein metabolism	endopeptidase activity -> peptidase activity	proteasome core complex (sensu Eukarya) -> cytoplasm, nucleus	REB1, SKO1
\|YNL251C\|	NRD1	nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	RNA binding -> RNA binding	nucleus -> nucleus	ABF1, MAC1
\|YGR184C\|	UBR1	protein polyubiquitination, protein monoubiquitination -> catabolism, protein metabolism	ubiquitin-protein ligase activity -> ligase activity\, forming carbon-nitrogen bonds	proteasome complex (sensu Eukarya) -> cytoplasm, nucleus	HMS1, REB1, RIM101
YFR050C	PRE4	ubiquitin-dependent protein catabolism -> catabolism, protein metabolism	endopeptidase activity -> peptidase activity	proteasome core complex (sensu Eukarya) -> cytoplasm, nucleus	MTH1, REB1
YGL201C	MCM6	DNA unwinding, DNA replication initiation -> cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	chromatin binding, ATP dependent DNA helicase activity -> DNA binding, adenyl nucleotide binding, hydrolase activity\, acting on acid anhydrides	cytoplasm, nucleus, pre-replicative complex -> cytoplasm, nucleus	MCM1
\|YJR015W\|	NO SYMBOL
YNL097C	PHO23	chromatin modification -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism		nucleus -> nucleus	MAC1
YGR124W	ASN2	asparagine biosynthesis -> amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis	asparagine synthase (glutamine-hydrolyzing) activity -> ligase activity\, forming carbon-nitrogen bonds		ASH1, ROX1
\|YGL096W\|	TOS8		transcription factor activity -> DNA binding		IXR1, SOK2, SWI4
YGL062W	PYC1	NADPH regeneration, gluconeogenesis -> coenzymes and prosthetic group metabolism, alcohol metabolism, carbohydrate metabolism, vitamin metabolism, biosynthesis, energy pathways	pyruvate carboxylase activity -> ligase activity\, forming carbon-carbon bonds	cytosol -> cytoplasm	DIG1, GCR1, STE12
\|YKL203C\|	TOR2	cytoskeleton organization and biogenesis, ribosome biogenesis, signal transduction, Rho protein signal transduction, regulation of cell cycle, G1 phase of mitotic cell cycle, cell cycle dependent actin filament reorganization -> cell organization and biogenesis, signal transduction, cell cycle, cytoplasm organization and biogenesis	phosphatidylinositol 3-kinase activity, protein binding -> transferase activity\, transferring phosphorus-containing groups, protein binding, lipid kinase activity	vacuolar membrane, plasma membrane -> cytoplasm, plasma membrane	BAS1, HIR1, REB1, RTG1
\|YGR060W\|	ERG25	ergosterol biosynthesis -> alcohol metabolism, biosynthesis, lipid metabolism	C-4 methyl sterol oxidase activity -> C-4 methyl sterol oxidase activity	endoplasmic reticulum membrane, plasma membrane -> cytoplasm, plasma membrane, endomembrane system	HSF1, MAL13, MET4, NDD1, SWI5
YKL145W	RPT1	ubiquitin-dependent protein catabolism -> catabolism, protein metabolism	ATPase activity, endopeptidase activity -> purine nucleotide binding, peptidase activity, hydrolase activity\, acting on acid anhydrides	proteasome regulatory particle (sensu Eukarya) -> cytoplasm, nucleus	REB1
YGR253C	PUP2	ubiquitin-dependent protein catabolism, response to stress, sporulation (sensu Saccharomyces) -> catabolism, response to stress, sporulation, protein metabolism	endopeptidase activity -> peptidase activity	proteasome core complex (sensu Eukarya) -> cytoplasm, nucleus	ABF1, HIR2, PHO4
YOR052C	NO SYMBOL
YDL126C	CDC48	ubiquitin-dependent protein catabolism, nonselective vesicle fusion, cell cycle, apoptosis, protein transport, ER-associated protein catabolism -> cell proliferation, cell death, macromolecule catabolism, transport, protein metabolism	ATPase activity -> purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleus, microsome, endoplasmic reticulum, cytosol -> nucleus, membrane fraction, cytoplasm	DAL82, MAL33, SWI4
YKL054C	DEF1	response to DNA damage, ubiquitin-dependent protein catabolism -> response to biotic stimulus, catabolism, protein metabolism		nucleus -> nucleus
YJR090C	GRR1	ubiquitin-dependent protein catabolism, G1/S transition of mitotic cell cycle -> catabolism, cell proliferation, protein metabolism	ubiquitin-protein ligase activity, protein binding -> ligase activity\, forming carbon-nitrogen bonds, protein binding	nuclear ubiquitin ligase complex, nucleus, cytoplasm, contractile ring (sensu Saccharomyces) -> nucleus, site of polarized growth (sensu Fungi), cell cortex, cytoplasm, ubiquitin ligase complex	REB1
YOR362C	PRE10	ubiquitin-dependent protein catabolism -> catabolism, protein metabolism	endopeptidase activity -> peptidase activity	proteasome core complex (sensu Eukarya) -> cytoplasm, nucleus
Main:		protein metabolism (0.56)	peptidase activity (0.33)	cytoplasm (0.80)	REB1 (0.40)
Score:		0.38	0.17	0.91	0.171
P-value:		1.337E-08 (ubiquitin-dependent protein catabolism)	7.207E-05 (endopeptidase activity)	6.134E-07 (proteasome complex (sensu Eukarya))	1.378E-03 (REB1)

ORF	SYMBOL	P	F	C	TF
YPR184W	GDB1	glycogen catabolism -> carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism	4-alpha-glucanotransferase activity, amylo-1\,6-glucosidase activity -> transferase activity\, transferring hexosyl groups, hydrolase activity\, hydrolyzing O-glycosyl compounds		CIN5
YOL087C	NO SYMBOL				DAL82
\|YNL098C\|	RAS2	pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction -> cell organization and biogenesis, sporulation, signal transduction	RAS small monomeric GTPase activity -> guanyl nucleotide binding, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides	plasma membrane -> plasma membrane	ACE2, SKN7
\|YIL052C\|	RPL34B	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	RME1
YGL062W	PYC1	NADPH regeneration, gluconeogenesis -> coenzymes and prosthetic group metabolism, alcohol metabolism, carbohydrate metabolism, vitamin metabolism, biosynthesis, energy pathways	pyruvate carboxylase activity -> pyruvate carboxylase activity	cytosol -> cytoplasm	DIG1, GCR1, STE12
YKL035W	UGP1	protein amino acid glycosylation, UDP-glucose metabolism -> biosynthesis, alcohol metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism, carbohydrate metabolism	UTP-glucose-1-phosphate uridylyltransferase activity -> nucleotidyltransferase activity
YFL036W	RPO41	mitochondrial genome maintenance, transcription from mitochondrial promoter -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	DNA-directed RNA polymerase activity -> nucleotidyltransferase activity	mitochondrial matrix -> cytoplasm
Main:		biosynthesis (0.50)	nucleotidyltransferase activity (0.33)	cytoplasm (0.75)	ACE2 (0.20)
Score:		0.47	0.07	0.50	0.000
P-value:		9.418E-02 (carbohydrate metabolism)	4.324E-02 (nucleotidyltransferase activity)	1.068E+00 (cytosol)	5.887E-01 (DAL82)

ORF	SYMBOL	P	F	C	TF
YNL138W	SRV2	cytoskeleton organization and biogenesis, RAS protein signal transduction -> cell organization and biogenesis, signal transduction	cytoskeletal protein binding, adenylate cyclase binding -> cytoskeletal protein binding, adenylate cyclase binding	actin cortical patch (sensu Saccharomyces) -> intracellular	ABF1
\|YMR280C\|	CAT8	gluconeogenesis, positive regulation of transcription from Pol II promoter -> alcohol metabolism, monosaccharide metabolism, carbohydrate metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, biosynthesis, energy pathways	specific RNA polymerase II transcription factor activity -> specific RNA polymerase II transcription factor activity	nucleus -> intracellular	ABF1, REB1
YOR317W	FAA1	N-terminal protein myristoylation, lipid metabolism, lipid transport -> biosynthesis, lipid metabolism, transport, protein metabolism	ligase activity -> ligase activity	lipid particle -> intracellular	ASH1, CIN5, HSF1, INO4, RAP1
YKR046C	PET10			lipid particle -> intracellular	ABF1
YAL016W	TPD3	protein biosynthesis, actin filament organization, mitotic spindle checkpoint, bud growth, protein amino acid dephosphorylation -> biosynthesis, cell organization and biogenesis, asexual reproduction, phosphorus metabolism, cell proliferation, cell cycle, protein metabolism	protein phosphatase type 2A activity -> protein phosphatase type 2A activity	protein phosphatase type 2A complex, bud neck, nucleus, cytoplasm, shmoo tip, bud tip, spindle pole body -> protein phosphatase type 2A complex, site of polarized growth (sensu Fungi), site of polarized growth (sensu Saccharomyces), intracellular	ABF1
YKL034W	TUL1	protein transport -> transport	ligase activity -> ligase activity	intracellular -> intracellular
YPL111W	CAR1	arginine catabolism to ornithine -> amine metabolism, nitrogen metabolism, amino acid and derivative metabolism, organic acid metabolism, catabolism	arginase activity -> arginase activity	cytosol -> intracellular	GCN4
YOR322C	NO SYMBOL				ABF1
\|YDL020C\|	RPN4	ubiquitin-dependent protein catabolism -> catabolism, protein metabolism	endopeptidase activity -> endopeptidase activity	proteasome regulatory particle (sensu Eukarya) -> intracellular	ABF1, CBF1, HSF1, PUT3, YAP1
Main:		biosynthesis (0.43)	ligase activity (0.29)	intracellular (1.00)	ABF1 (0.75)
Score:		0.38	0.05	1.00	0.571
P-value:		1.690E+00 (cytoskeleton organization and biogenesis)	1.516E-01 (ligase activity)	2.216E-02 (lipid particle)	7.301E-05 (ABF1)

ORF	SYMBOL	P	F	C	TF
YFL028C	CAF16	regulation of transcription\, DNA-dependent -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ATP-binding cassette (ABC) transporter activity -> ATP-binding cassette (ABC) transporter activity	CCR4-NOT complex, cytoplasm -> nucleus, cytoplasm
YFR028C	CDC14	DNA dependent DNA replication, protein amino acid dephosphorylation, regulation of exit from mitosis -> phosphorus metabolism, cell cycle, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism	protein phosphatase activity -> protein phosphatase activity	nucleus, spindle pole body, nucleolus -> cytoplasm, nucleus, microtubule organizing center
\|YMR300C\|	ADE4	purine base metabolism -> aromatic compound metabolism, heterocycle metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	amidophosphoribosyltransferase activity -> amidophosphoribosyltransferase activity		BAS1
YDR473C	PRP3	mRNA splicing -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	pre-mRNA splicing factor activity -> pre-mRNA splicing factor activity	small nuclear ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	ARG80, ARG81, DOT6, FZF1, GCR2, HAP4, HAP5, NRG1, RIM101, RLM1, RTG1, RTG3, SFP1, SRD1, STP1, THI2
YLR271W	NO SYMBOL
YKL211C	TRP3	tryptophan biosynthesis -> amine metabolism, aromatic compound biosynthesis, aromatic compound metabolism, amino acid and derivative metabolism, biosynthesis, organic acid metabolism, heterocycle metabolism	anthranilate synthase activity, indole-3-glycerol-phosphate synthase activity -> anthranilate synthase activity, indole-3-glycerol-phosphate synthase activity		CRZ1
\|YPR145W\|	ASN1	asparagine biosynthesis -> amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis	asparagine synthase (glutamine-hydrolyzing) activity -> asparagine synthase (glutamine-hydrolyzing) activity		DAL81, GCN4, GLN3, MET4, RAP1, SUM1
Main:		nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.67)	pre-mRNA splicing factor activity (0.17)	nucleus (1.00)	GCR2 (0.25)
Score:		0.53	0.00	1.00	0.000
P-value:		4.613E-02 (aromatic compound metabolism)	1.306E+00 (enzyme activity)	2.826E+00 (nucleus)	1.000E+00

ORF	SYMBOL	P	F	C	TF
YGR191W	HIP1	manganese ion transport, histidine transport -> transport, organic acid transport	histidine transporter activity -> carboxylic acid transporter activity	plasma membrane -> plasma membrane	GLN3, HAP3, HIR2, MBP1, MCM1, REB1, YAP1
\|YGR178C\|	PBP1	mRNA polyadenylation -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism		cytoplasm, nucleus -> cytoplasm, nucleus	CIN5, DOT6, MSS11
YML093W	UTP14	processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex
YDR361C	BCP1				ABF1, ARO80, GLN3, HAP5, IXR1, YAP1
YGL099W	LSG1	conjugation with cellular fusion, sporulation (sensu Saccharomyces), ribosome nucleus export -> conjugation, sporulation, cell organization and biogenesis, protein metabolism, transport, sexual reproduction	GTPase activity -> purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	cytoplasm -> cytoplasm	PHO4
\|YOL075C\|	NO SYMBOL				CRZ1, DAL82, SIP4
YJR070C	NO SYMBOL				GAT3, YAP5
YGR280C	PXR1	35S primary transcript processing, snRNA processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	RNA binding -> RNA binding	nucleolus -> nucleus
Main:		cell organization and biogenesis (0.60)	RNA binding (0.50)	nucleus (0.60)	YAP1 GLN3 (0.33)
Score:		0.60	0.17	0.40	0.067
P-value:		6.030E-02 (ribosome biogenesis)	6.400E-01 (RNA binding)	2.761E-01 (nucleolus)	9.199E-02 (GLN3)

ORF	SYMBOL	P	F	C	TF
YGR184C	UBR1	protein polyubiquitination, protein monoubiquitination -> ubiquitin-dependent protein catabolism, protein modification	ubiquitin-protein ligase activity -> ubiquitin-protein ligase activity	proteasome complex (sensu Eukarya) -> cytosol, endoplasmic reticulum, nucleus	HMS1, REB1, RIM101
YOR097C	NO SYMBOL
\|YJL045W\|	NO SYMBOL				MBP1, ROX1
YGL096W	TOS8		transcription factor activity -> transcription factor activity		IXR1, SOK2, SWI4
YOL038W	PRE6	ubiquitin-dependent protein catabolism -> ubiquitin-dependent protein catabolism	endopeptidase activity -> endopeptidase activity	proteasome core complex (sensu Eukarya) -> cytosol, endoplasmic reticulum, nucleus
\|YGR060W\|	ERG25	ergosterol biosynthesis -> ergosterol biosynthesis	C-4 methyl sterol oxidase activity -> C-4 methyl sterol oxidase activity	endoplasmic reticulum membrane, plasma membrane -> endoplasmic reticulum, plasma membrane, nuclear envelope-endoplasmic reticulum network	HSF1, MAL13, MET4, NDD1, SWI5
YHR027C	RPN1	ubiquitin-dependent protein catabolism -> ubiquitin-dependent protein catabolism	endopeptidase activity, receptor activity -> endopeptidase activity, receptor activity	proteasome regulatory particle (sensu Eukarya), endoplasmic reticulum, cytoplasm -> cytosol, endoplasmic reticulum, cytoplasm, nucleus
YDL126C	CDC48	ubiquitin-dependent protein catabolism, nonselective vesicle fusion, cell cycle, apoptosis, protein transport, ER-associated protein catabolism -> ubiquitin-dependent protein catabolism, nonselective vesicle fusion, cell cycle, apoptosis, protein transport, misfolded or incompletely synthesized protein catabolism	ATPase activity -> ATPase activity	nucleus, microsome, endoplasmic reticulum, cytosol -> nucleus, vesicular fraction, endoplasmic reticulum, cytosol	DAL82, MAL33, SWI4
YKL054C	DEF1	response to DNA damage, ubiquitin-dependent protein catabolism -> response to DNA damage, ubiquitin-dependent protein catabolism		nucleus -> nucleus
Main:		ubiquitin-dependent protein catabolism (0.83)	endopeptidase activity (0.33)	endoplasmic reticulum (0.83)	SWI4 (0.40)
Score:		0.67	0.07	0.93	0.100
P-value:		2.376E-05 (ubiquitin-dependent protein catabolism)	4.572E-02 (endopeptidase activity)	1.385E-03 (proteasome complex (sensu Eukarya))	7.177E-01 (MAL33)

ORF	SYMBOL	P	F	C	TF
YPL091W	GLR1	response to oxidative stress -> response to oxidative stress	glutathione reductase (NADPH) activity -> glutathione reductase (NADPH) activity
YOR173W	DCS2				CAD1
\|YFL056C\|	AAD6	aldehyde metabolism -> aldehyde metabolism	benzyl alcohol dehydrogenase activity -> benzyl alcohol dehydrogenase activity		ACE2, YAP1
YFR014C	CMK1	protein amino acid phosphorylation, signal transduction -> protein amino acid phosphorylation, signal transduction	calmodulin-dependent protein kinase I activity -> calmodulin-dependent protein kinase I activity	cytoplasm -> cytoplasm	USV1
YOL048C	NO SYMBOL				SKN7
YDR453C	TSA2	regulation of redox homeostasis -> regulation of redox homeostasis	thioredoxin peroxidase activity -> thioredoxin peroxidase activity	nucleus -> nucleus	SWI4
\|YPR005C\|	HAL1	salinity response, transcription initiation from Pol II promoter -> salinity response, transcription initiation from Pol II promoter		cytoplasm -> cytoplasm	CIN5
Main:		signal transduction (0.20)	calmodulin-dependent protein kinase I activity (0.25)	cytoplasm (0.67)	SWI4 (0.17)
Score:		0.00	0.00	0.33	0.000
P-value:		3.521E-01 (response to stress)	4.856E-02 (oxidoreductase activity)	4.860E+00 (cytoplasm)	4.959E-01 (USV1)

ORF	SYMBOL	P	F	C	TF
YJL005W	CYR1	meiosis, G-protein signaling\, coupled to cAMP nucleotide second messenger, RAS protein signal transduction, regulation of cell cycle -> nuclear division, G-protein coupled receptor protein signaling pathway, RAS protein signal transduction, regulation of cell cycle, cyclic-nucleotide-mediated signaling	adenylate cyclase activity -> adenylate cyclase activity	plasma membrane -> plasma membrane
YMR019W	STB4		DNA binding -> DNA binding	nucleus -> nucleus	PHD1, SKN7, SWI4
\|YPR015C\|	NO SYMBOL
YLR328W	NMA1	nicotinamide adenine dinucleotide metabolism -> pyridine nucleotide metabolism	nicotinamide-nucleotide adenylyltransferase activity -> nicotinamide-nucleotide adenylyltransferase activity		CIN5, MSN1, ROX1
YDR462W	MRPL28	protein biosynthesis -> protein biosynthesis	structural constituent of ribosome -> structural constituent of ribosome	mitochondrial large ribosomal subunit -> mitochondrial large ribosomal subunit	ABF1
YMR148W	NO SYMBOL
\|YOR212W\|	STE4	signal transduction during conjugation with cellular fusion -> G-protein coupled receptor protein signaling pathway, conjugation with cellular fusion, chemosensory perception	heterotrimeric G-protein GTPase activity -> heterotrimeric G-protein GTPase activity	heterotrimeric G-protein complex, plasma membrane, shmoo tip -> heterotrimeric G-protein complex, plasma membrane, shmoo tip
Main:		G-protein coupled receptor protein signaling pathway (0.50)	nicotinamide-nucleotide adenylyltransferase activity (0.20)	plasma membrane (0.50)	ABF1 (0.33)
Score:		0.17	0.00	0.17	0.000
P-value:		9.778E-03 (G-protein coupled receptor protein signaling pathway)	2.754E+00 (binding)	4.795E-01 (plasma membrane)	2.021E-01 (MSN1)