Binding site rules

RPN4(1) AND MCM1'(1) AND SCB(1) => SimExpr(YGR142W) : 5

EXPR: (0.085) RPN4 (P < 0.000) MCM1' (P < 0.000) SCB (P < 0.000)

ORF SYMBOL P F C TF
YCR061W NO SYMBOL HSF1
YGR142W BTN2 regulation of pH, intracellular protein transport ->
regulation of pH, intracellular protein transport cytosol ->
cytoplasm HSF1, MSN4
YJL045W NO SYMBOL MBP1, ROX1
YHL024W RIM4 sporulation, meiosis, premeiotic DNA synthesis, meiotic recombination ->
sporulation, meiosis, premeiotic DNA synthesis, meiotic recombination RNA binding ->
RNA binding cytoplasm ->
cytoplasm FKH2, PHD1
YGL096W TOS8 transcription factor activity ->
transcription factor activity IXR1, SOK2, SWI4
Main: premeiotic DNA synthesis (0.50) RNA binding (0.50) cytoplasm (1.00) HSF1 (0.40)
Score: 0.00 0.00 1.00 0.100
P-value: 4.252E+00 (cell growth and/or maintenance) 7.667E-01 (nucleic acid binding) 4.409E+00 (cytoplasm) 5.771E-02 (HSF1)

ALPHA2(1) AND PAC(1) => SimExpr(YPL106C) OR SimExpr(other) : 17 3

EXPR: (0.158) ALPHA2 (P < 0.000) PAC (P < 0.093)

ORF SYMBOL P F C TF
YIL096C NO SYMBOL GAT3, HAP2, MOT3, RTS2
YJR070C NO SYMBOL GAT3, YAP5
YHR027C RPN1 ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism endopeptidase activity, receptor activity ->
peptidase activity, receptor activity proteasome regulatory particle (sensu Eukarya), endoplasmic reticulum, cytoplasm ->
cytoplasm, nucleus
YDR364C CDC40 DNA replication, S phase of mitotic cell cycle, mRNA splicing, mitotic spindle assembly (sensu Saccharomyces) ->
cytoplasm organization and biogenesis, cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, M phase nucleic acid binding, pre-mRNA splicing factor activity ->
nucleic acid binding spliceosome complex, nuclear membrane, nuclear pore ->
nucleus, ribonucleoprotein complex, membrane
YKL172W EBP2 rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism nucleolus ->
nucleus ABF1, FZF1, RFX1
|YML108W| NO SYMBOL
YLR336C SGD1 osmoregulation ->
osmoregulation nucleus ->
nucleus
YFL007W BLM3 membrane ->
membrane
YLR222C UTP13 processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism snoRNA binding ->
nucleic acid binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex ABF1
YJL033W HCA4 35S primary transcript processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ATP dependent RNA helicase activity ->
nucleic acid binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus HIR2, USV1
YGL029W CGR1 ribosome biogenesis, rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism nucleolus ->
nucleus
|YPR183W| DPM1 N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
lipid biosynthesis, biosynthesis, membrane lipid metabolism, protein metabolism, lipoprotein metabolism transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
cytoplasm, membrane SWI5
YNR046W NO SYMBOL ABF1
YDR312W SSF2 ribosomal large subunit assembly and maintenance, conjugation with cellular fusion ->
cell organization and biogenesis, conjugation, sexual reproduction rRNA binding ->
nucleic acid binding nucleolus ->
nucleus ABF1, FKH2, INO4, RAP1
YMR049C ERB1 rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RTG3
YNL023C FAP1 transcription factor activity ->
nucleic acid binding
|YOR284W| HUA2 RFX1, YAP6
YHR128W FUR1 pyrimidine salvage ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism uracil phosphoribosyltransferase activity ->
transferase activity\, transferring glycosyl groups CIN5
YPL106C SSE1 protein folding ->
protein metabolism co-chaperone activity ->
co-chaperone activity cytoplasm ->
cytoplasm HSF1, MSN4
YLR249W YEF3 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex INO2, INO4
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.54) nucleic acid binding (0.60) nucleus (0.67) ABF1 (0.31)
Score: 0.44 0.36 0.59 0.115
P-value: 3.866E-03 (ribosome biogenesis and assembly) 4.710E-01 (RNA binding) 8.984E-03 (nucleolus) 7.648E-01 (GAT3)

ALPHA2(1) AND ALPHA1'(1) AND PAC(1) => SimExpr(YPL106C) OR SimExpr(other) : 8 1

EXPR: (0.146) ALPHA2 (P < 0.000) ALPHA1' (P < 0.000) PAC (P < 0.117)

ORF SYMBOL P F C TF
YJR070C NO SYMBOL GAT3, YAP5
YDR364C CDC40 DNA replication, S phase of mitotic cell cycle, mRNA splicing, mitotic spindle assembly (sensu Saccharomyces) ->
cytoplasm organization and biogenesis, cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, M phase nucleic acid binding, pre-mRNA splicing factor activity ->
nucleic acid binding spliceosome complex, nuclear membrane, nuclear pore ->
nucleus, pore complex, ribonucleoprotein complex, endomembrane system
YLR222C UTP13 processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism snoRNA binding ->
nucleic acid binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex ABF1
YJL033W HCA4 35S primary transcript processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ATP dependent RNA helicase activity ->
nucleic acid binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus HIR2, USV1
YGL029W CGR1 ribosome biogenesis, rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism nucleolus ->
nucleus
|YPR183W| DPM1 N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
lipid biosynthesis, biosynthesis, membrane lipid metabolism, protein metabolism, lipoprotein metabolism transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
cytoplasm, endomembrane system SWI5
YMR049C ERB1 rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RTG3
YHR128W FUR1 pyrimidine salvage ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism uracil phosphoribosyltransferase activity ->
transferase activity\, transferring glycosyl groups CIN5
YPL106C SSE1 protein folding ->
protein metabolism co-chaperone activity ->
co-chaperone activity cytoplasm ->
cytoplasm HSF1, MSN4
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.75) nucleic acid binding (0.50) nucleus (0.67) ABF1 (0.14)
Score: 0.61 0.27 0.53 0.000
P-value: 1.416E-03 (rRNA processing) 1.688E-01 (transferase activity\, transferring glycosyl groups) 4.202E-02 (nucleolus) 9.905E-01 (MSN4)

SFF'(1) AND PAC(1) => SimExpr(YGR280C) OR SimExpr(other) : 71 31

EXPR: (0.176) SFF' (P < 0.000) PAC (P < 0.689)

SWI5(1) AND PAC(1) => SimExpr(YGR280C) OR SimExpr(other) : 25 10

EXPR: (0.174) SWI5 (P < 0.000) PAC (P < 0.602)

SFF'(1) AND PAC(1) AND SCB(1) => SimExpr(YGR280C) OR SimExpr(other) : 23 8

EXPR: (0.141) SFF' (P < 0.000) PAC (P < 0.103) SCB (P < 0.000)

LYS14(1) AND PAC(1) => SimExpr(YGR280C) OR SimExpr(other) : 13 6

EXPR: (0.145) LYS14 (P < 0.000) PAC (P < 0.209)

ORF SYMBOL P F C TF
|YLR049C| NO SYMBOL MBP1, SWI5
YHR052W CIC1 protein catabolism ->
catabolism, protein metabolism protein binding\, bridging ->
protein binding\, bridging nucleolus, proteasome complex (sensu Eukarya) ->
nucleus, cytoplasm HAP4, MATa1
YML093W UTP14 processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
|YOL075C| NO SYMBOL CRZ1, DAL82, SIP4
YJR070C NO SYMBOL GAT3, YAP5
YBR034C HMT1 peptidyl-arginine modification, mRNA-nucleus export ->
protein metabolism, transport, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism protein-arginine N-methyltransferase activity ->
transferase activity\, transferring one-carbon groups nucleus ->
nucleus
YMR259C NO SYMBOL ARG80, GCR2, GTS1, HIR1, SRD1
|YHL017W| NO SYMBOL SIP4
|YGR191W| HIP1 manganese ion transport, histidine transport ->
transport, organic acid transport histidine transporter activity ->
carboxylic acid transporter activity plasma membrane ->
plasma membrane GLN3, HAP3, HIR2, MBP1, MCM1, REB1, YAP1
|YGR178C| PBP1 mRNA polyadenylation ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism cytoplasm, nucleus ->
cytoplasm, nucleus CIN5, DOT6, MSS11
YNL163C RIA1 ribosome biogenesis ->
cell organization and biogenesis translation elongation factor activity ->
translation factor activity\, nucleic acid binding cytoplasm ->
cytoplasm FHL1, RAP1, YAP5
YNL141W AAH1 adenine catabolism ->
aromatic compound metabolism, catabolism, heterocycle metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism adenine deaminase activity ->
hydrolase activity\, acting on carbon-nitrogen (but not peptide) bonds YFL044C
YHR128W FUR1 pyrimidine salvage ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism uracil phosphoribosyltransferase activity ->
transferase activity\, transferring glycosyl groups CIN5
YMR290C HAS1 nucleolus, nuclear membrane ->
nucleus, endomembrane system RAP1
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding nucleolus ->
nucleus
YNL110C NOP15 ribosomal large subunit biogenesis ->
cell organization and biogenesis nucleus, nucleolus ->
nucleus
YDR361C BCP1 ABF1, ARO80, GLN3, HAP5, IXR1, YAP1
YGL099W LSG1 conjugation with cellular fusion, sporulation (sensu Saccharomyces), ribosome nucleus export ->
conjugation, sporulation, cell organization and biogenesis, protein metabolism, transport, sexual reproduction GTPase activity ->
purine nucleotide binding, hydrolase activity\, acting on acid anhydrides cytoplasm ->
cytoplasm PHO4
|YOL141W| PPM2 C-terminal protein carboxyl methyltransferase activity ->
transferase activity\, transferring one-carbon groups ARG81, SRD1
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.55) RNA binding (0.20) nucleus (0.70) RAP1 CIN5 YAP1 GLN3 MBP1 SIP4 YAP5 SRD1 (0.13)
Score: 0.55 0.04 0.58 0.067
P-value: 1.266E-02 (ribosome biogenesis) 2.403E-01 (methyltransferase activity) 5.054E-03 (nucleolus) 8.118E-01 (GLN3)

SWI5(1) AND PAC(1) AND SCB(1) => SimExpr(YGR280C) OR SimExpr(other) : 9 3

EXPR: (0.119) SWI5 (P < 0.000) PAC (P < 0.075) SCB (P < 0.000)

ORF SYMBOL P F C TF
|YLR049C| NO SYMBOL MBP1, SWI5
YJL109C UTP10 processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
YDR399W HPT1 purine nucleotide biosynthesis ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism hypoxanthine phosphoribosyltransferase activity ->
transferase activity\, transferring glycosyl groups
YIL066C RNR3 DNA replication ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ribonucleoside-diphosphate reductase activity ->
oxidoreductase activity\, acting on CH2 groups cytoplasm ->
cytoplasm RFX1, STB1
YOR294W RRS1 ribosome biogenesis, rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism nucleus ->
nucleus STB1
YMR259C NO SYMBOL ARG80, GCR2, GTS1, HIR1, SRD1
YOR310C NOP58 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex ABF1, SWI6
|YLL010C| PSR1 response to stress ->
response to stress protein phosphatase activity ->
hydrolase activity\, acting on ester bonds plasma membrane ->
plasma membrane CBF1
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding nucleolus ->
nucleus
YDR312W SSF2 ribosomal large subunit assembly and maintenance, conjugation with cellular fusion ->
cell organization and biogenesis, conjugation, sexual reproduction rRNA binding ->
RNA binding nucleolus ->
nucleus ABF1, FKH2, INO4, RAP1
|YKL120W| OAC1 oxaloacetate transport, sulfate transport ->
transport oxaloacetate carrier activity, sulfate porter activity ->
electrochemical potential-driven transporter activity, anion transporter activity, organic cation transporter activity, carboxylic acid transporter activity mitochondrial inner membrane ->
cytoplasm, inner membrane LEU3, MTH1
YLR249W YEF3 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
translation factor activity\, nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex INO2, INO4
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.60) RNA binding (0.38) nucleus (0.56) ABF1 INO4 STB1 (0.22)
Score: 0.44 0.11 0.42 0.083
P-value: 2.257E-03 (ribosome biogenesis and assembly) 3.072E-01 (RNA binding) 8.745E-03 (nucleolus) 1.682E-01 (STB1)

SFF'(1) AND PAC(1) AND MCM1'(1) AND SCB(1) => SimExpr(YGR280C) OR SimExpr(other) : 5 1

EXPR: (0.105) SFF' (P < 0.000) PAC (P < 0.115) MCM1' (P < 0.000) SCB (P < 0.000)

ORF SYMBOL P F C TF
YIL118W RHO3 exocytosis, small GTPase mediated signal transduction, establishment of cell polarity (sensu Saccharomyces), actin filament organization ->
signal transduction, cell organization and biogenesis, transport Rho small monomeric GTPase activity, signal transducer activity ->
purine nucleotide binding, signal transducer activity, hydrolase activity\, acting on acid anhydrides intracellular ->
intracellular CIN5, NRG1, PHD1, SKN7, SOK2, YAP6
YIL066C RNR3 DNA replication ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ribonucleoside-diphosphate reductase activity ->
oxidoreductase activity\, acting on CH2 groups cytoplasm ->
intracellular RFX1, STB1
YOR310C NOP58 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex ->
intracellular ABF1, SWI6
|YLL010C| PSR1 response to stress ->
response to stress protein phosphatase activity ->
hydrolase activity\, acting on ester bonds plasma membrane ->
plasma membrane CBF1
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding nucleolus ->
intracellular
YGR158C MTR3 35S primary transcript processing, mRNA catabolism ->
cell organization and biogenesis, catabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism 3'-5' exoribonuclease activity ->
hydrolase activity\, acting on ester bonds, RNA binding nuclear exosome (RNase complex), cytoplasmic exosome (RNase complex) ->
intracellular ZMS1
Main: cell organization and biogenesis (0.67) RNA binding (0.40) intracellular (0.83) ABF1 (0.20)
Score: 0.60 0.20 0.67 0.000
P-value: 6.101E-04 (35S primary transcript processing) 4.216E-01 (hydrolase activity\, acting on ester bonds) 1.464E-01 (nucleolus) 4.452E-01 (ZMS1)

mRRPE(1) AND PAC(1) => SimExpr(YGR280C) OR SimExpr(other) : 79 6

EXPR: (0.110) mRRPE (P < 0.000) PAC (P < 0.000)

REB1(1) AND PAC(1) => SimExpr(YGR280C) OR SimExpr(other) : 6 1

EXPR: (0.133) REB1 (P < 0.004) PAC (P < 0.211)

ORF SYMBOL P F C TF
YPL266W DIM1 rRNA modification, 35S primary transcript processing ->
RNA modification, ribosome biogenesis, rRNA metabolism, RNA processing, transcription from Pol I promoter rRNA (adenine-N6\,N6-)-dimethyltransferase activity ->
rRNA (adenine-N6\,N6-)-dimethyltransferase activity nucleolus ->
nucleolus ARG81, STP2
YML043C RRN11 transcription from Pol I promoter ->
transcription from Pol I promoter RNA polymerase I transcription factor activity ->
RNA polymerase I transcription factor activity RNA polymerase I transcription factor complex ->
nucleolus, transcription factor complex MAL13
|YKL142W| MRP8 protein biosynthesis ->
protein biosynthesis structural constituent of ribosome ->
structural constituent of ribosome mitochondrial ribosome ->
mitochondrial matrix, organellar ribosome ACE2, CIN5, MBP1, PHO4, REB1, SKN7, STB1
YNL308C KRI1 ribosome biogenesis ->
ribosome biogenesis nucleolus ->
nucleolus
YOR272W YTM1 chromosome organization and biogenesis (sensu Eukarya), ribosomal large subunit biogenesis ->
chromosome organization and biogenesis (sensu Eukarya), ribosome biogenesis nucleus, nucleolus ->
nucleus, nucleolus LEU3, PUT3, REB1
YOR021C NO SYMBOL ARG80, GCR2
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
ribosome biogenesis, snRNA processing, RNA processing, transcription from Pol I promoter RNA binding ->
RNA binding nucleolus ->
nucleolus
Main: ribosome biogenesis (0.67) structural constituent of ribosome (0.25) nucleolus (0.83) REB1 (0.40)
Score: 0.53 0.00 0.67 0.100
P-value: 1.192E-03 (ribosome biogenesis) 2.000E+00 9.924E-06 (nucleolus) 3.338E-01 (REB1)

mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YGR280C) OR SimExpr(other) : 21 1

EXPR: (0.098) mRRPE (P < 0.000) PAC (P < 0.000) SCB (P < 0.000)

REB1(1) AND SWI5(1) AND SCB(1) => SimExpr(YGR280C) OR SimExpr(other) : 6 2

EXPR: (0.197) SWI5 (P < 0.023) REB1 (P < 0.066) SCB (P < 0.082)

ORF SYMBOL P F C TF
YDL232W OST4 N-linked glycosylation ->
biosynthesis, protein metabolism dolichyl-diphospho-oligosaccharide-protein glycosyltransferase activity, protein binding\, bridging ->
dolichyl-diphospho-oligosaccharide-protein glycosyltransferase activity, protein binding\, bridging endoplasmic reticulum membrane ->
cytoplasm, endomembrane system REB1
YPL237W SUI3 translational initiation ->
biosynthesis, protein metabolism translation initiation factor activity ->
translation initiation factor activity ribosome ->
cytoplasm, ribonucleoprotein complex
YMR121C RPL15B protein biosynthesis ->
biosynthesis, protein metabolism RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex REB1
YNL111C CYB5 sterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism electron transporter activity ->
electron transporter activity microsome ->
membrane fraction ABF1, GCR2, GTS1, NRG1, REB1, ROX1
|YMR186W| HSC82 protein folding, response to stress ->
protein metabolism, response to stress cation-transporting ATPase activity, chaperone activity ->
cation-transporting ATPase activity, chaperone activity BAS1, HAP2, HSF1, INO4, REB1, ROX1
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding nucleolus ->
nucleus
YOL006C TOP1 negative regulation of recombination within rDNA repeats, DNA topological change, DNA strand elongation, chromatin assembly/disassembly, regulation of transcription from Pol II promoter, RNA elongation from Pol II promoter, mitotic chromosome condensation, nuclear migration ->
cell organization and biogenesis, cell cycle, mitotic cell cycle, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DNA topoisomerase type I activity ->
DNA topoisomerase type I activity nucleus ->
nucleus REB1
|YMR002W| NO SYMBOL NDD1, REB1, SWI6
Main: biosynthesis (0.57) RNA binding (0.29) cytoplasm (0.50) REB1 (1.00)
Score: 0.48 0.05 0.27 1.000
P-value: 6.902E-01 (protein biosynthesis) 4.182E-01 (binding) 1.018E+00 (ribosome) 5.891E-07 (REB1)

REB1(1) AND ALPHA1'(1) AND PAC(1) => SimExpr(YGR280C) : 5

EXPR: (0.067) ALPHA1' (P < 0.000) REB1 (P < 0.000) PAC (P < 0.006)

ORF SYMBOL P F C TF
YML043C RRN11 transcription from Pol I promoter ->
transcription from Pol I promoter RNA polymerase I transcription factor activity ->
RNA polymerase I transcription factor activity RNA polymerase I transcription factor complex ->
nucleolus, transcription factor complex MAL13
YNL308C KRI1 ribosome biogenesis ->
ribosome biogenesis nucleolus ->
nucleolus
YOR272W YTM1 chromosome organization and biogenesis (sensu Eukarya), ribosomal large subunit biogenesis ->
chromosome organization and biogenesis (sensu Eukarya), ribosome biogenesis nucleus, nucleolus ->
nucleus, nucleolus LEU3, PUT3, REB1
YOR021C NO SYMBOL ARG80, GCR2
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
ribosome biogenesis, snRNA processing, RNA processing, transcription from Pol I promoter RNA binding ->
RNA binding nucleolus ->
nucleolus
Main: ribosome biogenesis (0.75) RNA polymerase I transcription factor activity (0.50) nucleolus (1.00) GCR2 (0.33)
Score: 0.67 0.00 1.00 0.000
P-value: 7.362E-03 (ribosome biogenesis) 2.000E+00 6.546E-05 (nucleolus) 2.166E-01 (PUT3)

LYS14(1) AND mRRPE(1) AND PAC(1) => SimExpr(YGR280C) : 9

EXPR: (0.068) LYS14 (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.000)

SFF'(1) AND mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YGR280C) : 13

EXPR: (0.094) SFF' (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.007) SCB (P < 0.000)

RAP1(1) AND ALPHA1'(1) => SimExpr(YOL120C) OR SimExpr(other) : 30 11

EXPR: (0.168) ALPHA1' (P < 0.000) RAP1 (P < 0.429)

RAP1(1) AND ATRepeat(1) => SimExpr(YOL120C) OR SimExpr(other) : 6 1

EXPR: (0.131) ATRepeat (P < 0.000) RAP1 (P < 0.218)

RAP1(1) AND MCM1'(1) => SimExpr(YOL120C) OR SimExpr(other) : 17 6

EXPR: (0.155) MCM1' (P < 0.000) RAP1 (P < 0.271)

RAP1(1) AND mRRPE(1) => SimExpr(YOL120C) OR SimExpr(other) : 11 2

EXPR: (0.126) mRRPE (P < 0.001) RAP1 (P < 0.093)

RAP1(1) AND SWI5(1) => SimExpr(YOL120C) OR SimExpr(other) : 21 7

EXPR: (0.160) SWI5 (P < 0.000) RAP1 (P < 0.347)

RAP1(1) AND STRE(1) => SimExpr(YOL120C) : 5

EXPR: (0.067) STRE (P < 0.000) RAP1 (P < 0.007)

RAP1(1) AND SWI5(1) AND MCM1'(1) => SimExpr(YOL120C) : 7

EXPR: (0.065) SWI5 (P < 0.000) MCM1' (P < 0.000) RAP1 (P < 0.002)

MCM1(1) AND STRE(1) => SimExpr(YKL035W) OR SimExpr(other) : 5 2

EXPR: (0.173) STRE (P < 0.006) MCM1 (P < 0.000)

ORF SYMBOL P F C TF
YLR028C ADE16 'de novo' IMP biosynthesis, aerobic respiration, sporulation (sensu Saccharomyces) ->
energy pathways, sporulation, biosynthesis, nucleotide metabolism IMP cyclohydrolase activity, phosphoribosylaminoimidazole-carboxamide formyltransferase activity ->
IMP cyclohydrolase activity, phosphoribosylaminoimidazole-carboxamide formyltransferase activity cytosol ->
cytoplasm
YLR201C NO SYMBOL ABF1
YJL079C PRY1 nuclear membrane, endoplasmic reticulum ->
nucleus, cytoplasm, endomembrane system NDD1, PHD1, RAP1
YOL087C NO SYMBOL DAL82
|YJL082W| IML2
YKL035W UGP1 protein amino acid glycosylation, UDP-glucose metabolism ->
biosynthesis, alcohol metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism, carbohydrate metabolism UTP-glucose-1-phosphate uridylyltransferase activity ->
UTP-glucose-1-phosphate uridylyltransferase activity
|YMR291W| NO SYMBOL RAP1
Main: biosynthesis (1.00) UTP-glucose-1-phosphate uridylyltransferase activity (0.50) cytoplasm (1.00) RAP1 (0.50)
Score: 1.00 0.00 1.00 0.167
P-value: 2.707E+00 (biosynthesis) 1.260E+00 (transferase activity) 4.849E+00 (cytoplasm) 2.885E-01 (RAP1)

ALPHA2(1) AND ALPHA1'(1) AND mRRPE(1) => SimExpr(YNL111C) OR SimExpr(other) : 15 7

EXPR: (0.180) ALPHA2 (P < 0.000) ALPHA1' (P < 0.000) mRRPE (P < 0.033)

ORF SYMBOL P F C TF
|YPL193W| RSA1 ribosomal large subunit assembly and maintenance ->
cell organization and biogenesis nucleoplasm ->
nucleus
|YBR213W| MET8 sulfate assimilation, siroheme biosynthesis ->
sulfur metabolism, pigment metabolism, coenzymes and prosthetic group biosynthesis, coenzymes and prosthetic group metabolism, biosynthesis, heterocycle metabolism siroheme synthase activity, ferrochelatase activity ->
siroheme synthase activity, other lyase activity IME4
YJL033W HCA4 35S primary transcript processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus HIR2, USV1
YJR070C NO SYMBOL GAT3, YAP5
|YDR297W| SUR2 sphingolipid metabolism, sphingolipid biosynthesis ->
lipid metabolism, biosynthesis sphingosine hydroxylase activity ->
sphingosine hydroxylase activity endoplasmic reticulum ->
cytoplasm CBF1, MTH1
|YPR036W| VMA13 vacuolar acidification ->
cell homeostasis, cell organization and biogenesis, transport hydrogen-exporting ATPase activity ->
purine nucleotide binding, cation transporter activity, primary active transporter activity, hydrolase activity\, acting on acid anhydrides hydrogen-transporting ATPase V1 domain, vacuolar membrane (sensu Fungi) ->
cytoplasm, vacuole
|YPR183W| DPM1 N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
lipid biosynthesis, biosynthesis, membrane lipid metabolism, protein metabolism, lipoprotein metabolism transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
cytoplasm, endomembrane system SWI5
YMR049C ERB1 rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RTG3
YNL111C CYB5 sterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism electron transporter activity ->
electron transporter activity microsome ->
membrane fraction ABF1, GCR2, GTS1, NRG1, REB1, ROX1
YJL110C GZF3 regulation of nitrogen utilization, nitrogen metabolism, negative regulation of transcription from Pol II promoter ->
nitrogen metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription specific RNA polymerase II transcription factor activity ->
specific RNA polymerase II transcription factor activity nucleus ->
nucleus ABF1, SIP4
|YIL014W| MNT3 O-linked glycosylation ->
biosynthesis, protein metabolism alpha-1\,3-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups AZF1, GCR2, HIR1, RME1, ROX1
YGL029W CGR1 ribosome biogenesis, rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism nucleolus ->
nucleus
YHR128W FUR1 pyrimidine salvage ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism uracil phosphoribosyltransferase activity ->
transferase activity\, transferring glycosyl groups CIN5
YOL014W NO SYMBOL
YBR048W RPS11B protein biosynthesis, ribosomal small subunit assembly and maintenance, regulation of translational fidelity ->
cell organization and biogenesis, biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex GAL4, HAP4, LEU3, MET31, MSN1
YGL195W GCN1 regulation of translational elongation ->
biosynthesis, protein metabolism cytosol, cytosolic ribosome (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex ABF1, GCR1, HAP3, MAC1, RLM1, ROX1
YNR054C NO SYMBOL HAP3, HAP5, IXR1, MCM1, RTG3, SFP1, SWI6
|YBR294W| SUL1 sulfate transport ->
transport sulfate transporter activity ->
anion transporter activity plasma membrane ->
plasma membrane STB1
YLR222C UTP13 processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex ABF1
YDR023W SES1 amino acid activation ->
biosynthesis, protein metabolism serine-tRNA ligase activity ->
ligase activity\, forming carbon-oxygen bonds, ligase activity\, forming phosphoric ester bonds cytoplasm ->
cytoplasm GRF10(Pho2), MOT3
YGR001C NO SYMBOL
YDL167C NRP1
Main: biosynthesis (0.53) transferase activity\, transferring glycosyl groups (0.23) cytoplasm (0.46) ABF1 (0.25)
Score: 0.49 0.06 0.35 0.083
P-value: 1.118E-02 (ribosome biogenesis and assembly) 3.497E-01 (mannosyltransferase activity) 6.936E-01 (nucleolus) 5.474E-01 (ROX1)

ALPHA1(1) AND ALPHA2(1) AND SWI5(1) AND SCB(1) => SimExpr(YNL111C) OR SimExpr(other) : 11 3

EXPR: (0.174) ALPHA2 (P < 0.002) SWI5 (P < 0.002) SCB (P < 0.002) ALPHA1 (P < 0.000)

ORF SYMBOL P F C TF
YLR272C YCS4 mitotic chromosome condensation ->
cell proliferation, cell cycle nuclear condensin complex ->
chromosome, nucleus
YIL035C CKA1 flocculation, protein amino acid phosphorylation, cell ion homeostasis, G1/S transition of mitotic cell cycle, G2/M transition of mitotic cell cycle, establishment of cell polarity (sensu Saccharomyces), regulation of transcription from Pol I promoter, regulation of transcription from Pol III promoter, response to DNA damage ->
cell adhesion, phosphorus metabolism, cell homeostasis, cell proliferation, transcription, response to biotic stimulus, cell organization and biogenesis, protein metabolism protein kinase CK2 activity ->
protein kinase CK2 activity protein kinase CK2 complex ->
protein kinase CK2 complex ABF1
YBL087C RPL23A protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, IXR1, MSS11, PDR1, RAP1, SMP1, SOK2
YLL032C NO SYMBOL FZF1, GCR2, SRD1
YHR046C INM1 myo-inositol metabolism ->
alcohol metabolism, carbohydrate metabolism myo-inositol-1(or 4)-monophosphatase activity ->
myo-inositol-1(or 4)-monophosphatase activity
|YOR188W| MSB1 establishment of cell polarity (sensu Saccharomyces) ->
cell organization and biogenesis bud neck, bud tip ->
site of polarized growth (sensu Fungi)
YPR195C NO SYMBOL FKH1, FKH2, HIR1, HIR2, INO4, RLM1
|YPR185W| APG13 protein-vacuolar targeting, autophagy ->
cell organization and biogenesis, autophagy, protein metabolism, transport protein binding ->
protein binding extrinsic to membrane ->
extrinsic to membrane MET4, SWI6
YKL209C STE6 peptide pheromone export ->
transport ATP-binding cassette (ABC) transporter activity ->
ATP-binding cassette (ABC) transporter activity integral to plasma membrane, shmoo tip ->
integral to membrane, site of polarized growth (sensu Fungi), plasma membrane MCM1, STE12
|YOR111W| NO SYMBOL UGA3
YNL111C CYB5 sterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism electron transporter activity ->
electron transporter activity microsome ->
membrane fraction ABF1, GCR2, GTS1, NRG1, REB1, ROX1
YGR001C NO SYMBOL
YDR312W SSF2 ribosomal large subunit assembly and maintenance, conjugation with cellular fusion ->
cell organization and biogenesis, conjugation, sexual reproduction rRNA binding ->
rRNA binding nucleolus ->
nucleus ABF1, FKH2, INO4, RAP1
YLR249W YEF3 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
translation elongation factor activity ribosome ->
cytoplasm, ribonucleoprotein complex INO2, INO4
Main: cell organization and biogenesis (0.40) translation elongation factor activity (0.12) cytoplasm (0.22) ABF1 INO4 (0.30)
Score: 0.36 0.00 0.08 0.178
P-value: 7.522E-01 (establishment of cell polarity (sensu Fungi)) 3.763E+00 (transporter activity) 8.723E-01 (site of polarized growth (sensu Saccharomyces)) 1.824E-01 (INO4)

ALPHA1(1) AND ALPHA2(1) AND SFF'(1) AND mRRPE(1) AND SCB(1) => SimExpr(YNL111C) OR SimExpr(other) : 5 2

EXPR: (0.129) ALPHA2 (P < 0.005) SFF' (P < 0.001) mRRPE (P < 0.019) SCB (P < 0.006) ALPHA1 (P < 0.001)

ORF SYMBOL P F C TF
YLL032C NO SYMBOL FZF1, GCR2, SRD1
|YOR188W| MSB1 establishment of cell polarity (sensu Saccharomyces) ->
cell organization and biogenesis bud neck, bud tip ->
bud neck, bud tip
YDR040C ENA1 sodium ion transport ->
transport P-type ATPase activity ->
P-type ATPase activity plasma membrane ->
plasma membrane NRG1, SOK2
YNL123W NO SYMBOL ARO80
YNL111C CYB5 sterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism electron transporter activity ->
electron transporter activity microsome ->
microsome ABF1, GCR2, GTS1, NRG1, REB1, ROX1
|YMR164C| MSS11 positive regulation of transcription from Pol II promoter, starch catabolism, pseudohyphal growth ->
carbohydrate metabolism, cell organization and biogenesis, polysaccharide metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, catabolism specific RNA polymerase II transcription factor activity ->
specific RNA polymerase II transcription factor activity nucleus ->
nucleus
YLR249W YEF3 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
translation elongation factor activity ribosome ->
ribosome INO2, INO4
Main: cell organization and biogenesis (0.40) translation elongation factor activity (0.25) microsome (0.20) GCR2 NRG1 (0.40)
Score: 0.20 0.00 0.00 0.200
P-value: 3.610E+00 (biosynthesis) 8.559E-01 (transporter activity) 4.000E+00 (intracellular) 8.556E-02 (GCR2)

ALPHA1(1) AND ALPHA2(1) AND SFF(1) AND SWI5(1) AND SCB(1) => SimExpr(YNL111C) OR SimExpr(other) : 9 2

EXPR: (0.156) ALPHA2 (P < 0.000) SFF (P < 0.000) SWI5 (P < 0.000) SCB (P < 0.003) ALPHA1 (P < 0.000)

ORF SYMBOL P F C TF
YLR272C YCS4 mitotic chromosome condensation ->
cell proliferation, cell cycle nuclear condensin complex ->
chromosome, nucleus
YIL035C CKA1 flocculation, protein amino acid phosphorylation, cell ion homeostasis, G1/S transition of mitotic cell cycle, G2/M transition of mitotic cell cycle, establishment of cell polarity (sensu Saccharomyces), regulation of transcription from Pol I promoter, regulation of transcription from Pol III promoter, response to DNA damage ->
cell adhesion, phosphorus metabolism, cell homeostasis, cell proliferation, transcription, response to biotic stimulus, cell organization and biogenesis, protein metabolism protein kinase CK2 activity ->
protein kinase CK2 activity protein kinase CK2 complex ->
protein kinase CK2 complex ABF1
YBL087C RPL23A protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, IXR1, MSS11, PDR1, RAP1, SMP1, SOK2
YLL032C NO SYMBOL FZF1, GCR2, SRD1
|YOR188W| MSB1 establishment of cell polarity (sensu Saccharomyces) ->
cell organization and biogenesis bud neck, bud tip ->
site of polarized growth (sensu Fungi)
YPR195C NO SYMBOL FKH1, FKH2, HIR1, HIR2, INO4, RLM1
|YPR185W| APG13 protein-vacuolar targeting, autophagy ->
cell organization and biogenesis, autophagy, protein metabolism, transport protein binding ->
protein binding extrinsic to membrane ->
extrinsic to membrane MET4, SWI6
YKL209C STE6 peptide pheromone export ->
transport ATP-binding cassette (ABC) transporter activity ->
ATP-binding cassette (ABC) transporter activity integral to plasma membrane, shmoo tip ->
integral to membrane, site of polarized growth (sensu Fungi), plasma membrane MCM1, STE12
YNL111C CYB5 sterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism electron transporter activity ->
electron transporter activity microsome ->
membrane fraction ABF1, GCR2, GTS1, NRG1, REB1, ROX1
YDR312W SSF2 ribosomal large subunit assembly and maintenance, conjugation with cellular fusion ->
cell organization and biogenesis, conjugation, sexual reproduction rRNA binding ->
rRNA binding nucleolus ->
nucleus ABF1, FKH2, INO4, RAP1
YLR249W YEF3 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
translation elongation factor activity ribosome ->
cytoplasm, ribonucleoprotein complex INO2, INO4
Main: cell organization and biogenesis (0.44) translation elongation factor activity (0.14) cytoplasm (0.22) ABF1 INO4 (0.33)
Score: 0.42 0.00 0.08 0.222
P-value: 4.531E-01 (establishment of cell polarity (sensu Fungi)) 2.447E+00 (transporter activity) 5.606E-01 (site of polarized growth (sensu Saccharomyces)) 8.479E-02 (INO4)

ALPHA1(1) AND ALPHA2(1) AND SFF(1) AND mRRPE(1) AND SCB(1) => SimExpr(YNL111C) OR SimExpr(other) : 5 1

EXPR: (0.115) ALPHA2 (P < 0.002) SFF (P < 0.000) mRRPE (P < 0.019) SCB (P < 0.001) ALPHA1 (P < 0.001)

CSRE(1) AND mRRPE(1) AND SWI5(1) => SimExpr(YNL111C) OR SimExpr(other) : 8 3

EXPR: (0.176) mRRPE (P < 0.087) SWI5 (P < 0.002) CSRE (P < 0.000)

ORF SYMBOL P F C TF
YDR399W HPT1 purine nucleotide biosynthesis ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism hypoxanthine phosphoribosyltransferase activity ->
transferase activity\, transferring glycosyl groups
|YAR062W| NO SYMBOL
YGR245C SDA1 actin cytoskeleton organization and biogenesis, start control point of mitotic cell cycle ->
cell organization and biogenesis, cell proliferation nucleus ->
nucleus
YOR063W RPL3 protein biosynthesis, ribosomal large subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex GRF10(Pho2)
|YKL093W| MBR1 aerobic respiration ->
energy pathways
YNL111C CYB5 sterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism electron transporter activity ->
electron transporter activity microsome ->
membrane fraction ABF1, GCR2, GTS1, NRG1, REB1, ROX1
YKL181W PRS1 histidine biosynthesis, tryptophan biosynthesis, purine salvage, 'de novo' IMP biosynthesis, 'de novo' pyrimidine base biosynthesis ->
amine metabolism, nucleotide biosynthesis, purine ribonucleotide metabolism, aromatic compound metabolism, amino acid derivative biosynthesis, biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, amino acid and derivative metabolism, organic acid metabolism, heterocycle metabolism ribose-phosphate pyrophosphokinase activity ->
carbohydrate kinase activity, transferase activity\, transferring phosphorus-containing groups
|YHR213W| NO SYMBOL PHD1
YPR010C RPA135 transcription from Pol I promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DNA-directed RNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups DNA-directed RNA polymerase I complex ->
nucleus ROX1, SIG1
YOR310C NOP58 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex ABF1, SWI6
YOR342C NO SYMBOL RAP1
Main: biosynthesis (0.50) transferase activity\, transferring phosphorus-containing groups (0.40) nucleus (0.60) ABF1 ROX1 (0.33)
Score: 0.50 0.10 0.40 0.133
P-value: 2.375E-02 (purine nucleotide metabolism) 1.239E+00 (transferase activity\, transferring phosphorus-containing groups) 4.724E-01 (nucleolus) 3.000E-01 (ROX1)

REB1(1) AND SWI5(1) AND SCB(1) => SimExpr(YNL111C) OR SimExpr(other) : 6 2

REB1(1) AND PAC(1) => SimExpr(YML043C) OR SimExpr(other) : 6 1

REB1(1) AND ALPHA1'(1) AND PAC(1) => SimExpr(YML043C) : 5

REB1(1) AND PAC(1) => SimExpr(YNL308C) OR SimExpr(other) : 6 1

SFF'(1) AND STE12(1) AND PAC(1) => SimExpr(YNL308C) OR SimExpr(other) : 5 1

EXPR: (0.146) SFF' (P < 0.000) STE12 (P < 0.014) PAC (P < 0.294)

ORF SYMBOL P F C TF
|YKL142W| MRP8 protein biosynthesis ->
protein biosynthesis structural constituent of ribosome ->
structural constituent of ribosome mitochondrial ribosome ->
cytoplasm, ribonucleoprotein complex ACE2, CIN5, MBP1, PHO4, REB1, SKN7, STB1
YNL308C KRI1 ribosome biogenesis ->
ribosome biogenesis nucleolus ->
nucleus
YGR251W NO SYMBOL MSN4, PHD1, SKN7
YPR137W RRP9 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
RNA modification, ribosome biogenesis, rRNA metabolism, RNA processing, transcription from Pol I promoter snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex ABF1, HIR1, RCS1
YJL069C UTP18 ABF1
YGR158C MTR3 35S primary transcript processing, mRNA catabolism ->
ribosome biogenesis, mRNA catabolism, RNA processing, transcription from Pol I promoter 3'-5' exoribonuclease activity ->
hydrolase activity\, acting on ester bonds, RNA binding nuclear exosome (RNase complex), cytoplasmic exosome (RNase complex) ->
exosome (RNase complex), cytoplasm, nucleus ZMS1
Main: ribosome biogenesis (0.75) RNA binding (0.67) nucleus (0.75) ABF1 SKN7 (0.40)
Score: 0.50 0.33 0.83 0.200
P-value: 1.841E-02 (ribosome biogenesis) 3.259E-01 (RNA binding) 1.673E-01 (nucleolus) 2.060E-01 (SKN7)

mRRPE(1) AND STE12(1) AND PAC(1) => SimExpr(YNL308C) : 5

EXPR: (0.073) mRRPE (P < 0.000) STE12 (P < 0.000) PAC (P < 0.003)

ORF SYMBOL P F C TF
YNL308C KRI1 ribosome biogenesis ->
cell growth and/or maintenance nucleolus ->
nucleolus
YAL059W ECM1 cell wall organization and biogenesis ->
cell growth and/or maintenance MOT3
YBR247C ENP1 processing of 20S pre-rRNA, rRNA processing, cell growth and/or maintenance ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism snoRNA binding ->
snoRNA binding nucleolus, nucleus ->
nucleolus, nucleus
YMR310C NO SYMBOL
YJL069C UTP18 ABF1
Main: cell growth and/or maintenance (1.00) snoRNA binding (1.00) nucleolus (1.00) ABF1 (0.50)
Score: 1.00 0.00 1.00 0.000
P-value: 1.232E-01 (ribosome biogenesis) 0.000E+00 8.582E-02 (nucleolus) 1.782E-01 (MOT3)

REB1(1) AND ALPHA1'(1) AND PAC(1) => SimExpr(YNL308C) : 5

REB1(1) AND SWI5(1) AND SCB(1) => SimExpr(YOL006C) OR SimExpr(other) : 6 2

REB1(1) AND ALPHA1'(1) AND SFF'(1) AND SWI5(1) AND SCB(1) => SimExpr(YOL006C) : 6

EXPR: (0.086) ALPHA1' (P < 0.000) SFF' (P < 0.000) SWI5 (P < 0.000) REB1 (P < 0.000) SCB (P < 0.000)

REB1(1) AND ALPHA1'(1) AND SFF(1) AND SWI5(1) AND SCB(1) => SimExpr(YOL006C) : 5

EXPR: (0.073) ALPHA1' (P < 0.000) SFF (P < 0.000) SWI5 (P < 0.000) REB1 (P < 0.000) SCB (P < 0.000)

REB1(1) AND PAC(1) => SimExpr(YPL266W) OR SimExpr(other) : 6 1

CSRE(1) AND ALPHA2(1) AND SWI5(1) => SimExpr(YOR152C) OR SimExpr(other) : 9 4

EXPR: (0.223) ALPHA2 (P < 0.000) SWI5 (P < 0.000) CSRE (P < 0.000)

ORF SYMBOL P F C TF
YMR118C NO SYMBOL GTS1
YOL048C NO SYMBOL SKN7
YMR250W GAD1 response to oxidative stress, glutamate catabolism ->
oxygen and reactive oxygen species metabolism, amine metabolism, amino acid and derivative metabolism, organic acid metabolism, response to biotic stimulus, catabolism glutamate decarboxylase activity ->
carbon-carbon lyase activity cytoplasm ->
cytoplasm
YJL161W NO SYMBOL GRF10(Pho2), MAL13, NDD1
YJR019C TES1 fatty acid oxidation ->
lipid metabolism, organic acid metabolism acyl-CoA thioesterase activity ->
hydrolase activity\, acting on ester bonds peroxisome ->
cytoplasm DAL82, MTH1
|YOL055C| THI20 thiamin biosynthesis ->
biosynthesis, vitamin metabolism phosphomethylpyrimidine kinase activity ->
transferase activity\, transferring phosphorus-containing groups
YMR148W NO SYMBOL
YLR377C FBP1 gluconeogenesis ->
alcohol metabolism, carbohydrate metabolism, biosynthesis, energy pathways fructose-bisphosphatase activity ->
hydrolase activity\, acting on ester bonds cytosol ->
cytoplasm
|YNL111C| CYB5 sterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism electron transporter activity ->
electron transporter activity microsome ->
membrane fraction ABF1, GCR2, GTS1, NRG1, REB1, ROX1
YHR090C YNG2 chromatin modification ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism enzyme activator activity ->
enzyme activator activity histone acetyltransferase complex, nucleus ->
nucleus ABF1, FKH1
|YKR003W| OSH6 steroid biosynthesis ->
biosynthesis, lipid metabolism oxysterol binding ->
oxysterol binding
|YOR348C| PUT4 neutral amino acid transport ->
transport amino acid permease activity, neutral amino acid transporter activity ->
carboxylic acid transporter activity, polyamine transporter activity, electrochemical potential-driven transporter activity plasma membrane ->
plasma membrane SWI5
YOR152C NO SYMBOL HIR2
Main: biosynthesis (0.50) hydrolase activity\, acting on ester bonds (0.25) cytoplasm (0.50) ABF1 GTS1 (0.25)
Score: 0.32 0.04 0.20 0.071
P-value: 1.166E-01 (steroid biosynthesis) 1.227E+00 (hydrolase activity\, acting on ester bonds) 4.985E+00 (cytoplasm) 2.014E-01 (GTS1)

REB1(1) AND SWI5(1) AND SCB(1) => SimExpr(YPL237W) OR SimExpr(other) : 6 2

REB1(1) AND ALPHA1'(1) AND SFF'(1) AND SCB(1) => SimExpr(YPL237W) OR SimExpr(other) : 8 2

EXPR: (0.153) ALPHA1' (P < 0.000) SFF' (P < 0.000) REB1 (P < 0.000) SCB (P < 0.000)

ORF SYMBOL P F C TF
YDL232W OST4 N-linked glycosylation ->
biosynthesis, protein metabolism dolichyl-diphospho-oligosaccharide-protein glycosyltransferase activity, protein binding ->
dolichyl-diphospho-oligosaccharide-protein glycosyltransferase activity, protein binding endoplasmic reticulum membrane ->
cytoplasm, endomembrane system REB1
YML043C RRN11 transcription from Pol I promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA polymerase I transcription factor activity ->
RNA polymerase I transcription factor activity RNA polymerase I transcription factor complex ->
nucleus MAL13
YPL237W SUI3 translational initiation ->
biosynthesis, protein metabolism translation initiation factor activity ->
translation initiation factor activity ribosome ->
cytoplasm, ribonucleoprotein complex
|YGR179C| OKP1 chromosome segregation ->
cell proliferation protein binding ->
protein binding condensed nuclear chromosome kinetochore ->
condensed chromosome, chromosome, nucleus REB1
YMR121C RPL15B protein biosynthesis ->
biosynthesis, protein metabolism RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex REB1
|YKR015C| NO SYMBOL ABF1, REB1, SUM1
YNL111C CYB5 sterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism electron transporter activity ->
electron transporter activity microsome ->
membrane fraction ABF1, GCR2, GTS1, NRG1, REB1, ROX1
YLR378C SEC61 SRP-dependent cotranslational membrane targeting\, translocation ->
cell organization and biogenesis, protein metabolism, transport protein transporter activity ->
protein transporter activity endoplasmic reticulum membrane, endoplasmic reticulum lumen, translocon ->
cytoplasm, endoplasmic reticulum, endomembrane system MAL13, REB1
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding nucleolus ->
nucleus
YOL006C TOP1 negative regulation of recombination within rDNA repeats, DNA topological change, DNA strand elongation, chromatin assembly/disassembly, regulation of transcription from Pol II promoter, RNA elongation from Pol II promoter, mitotic chromosome condensation, nuclear migration ->
cell organization and biogenesis, cell cycle, mitotic cell cycle, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DNA topoisomerase type I activity ->
DNA topoisomerase type I activity nucleus ->
nucleus REB1
Main: biosynthesis (0.44) protein binding (0.22) cytoplasm (0.44) REB1 (0.88)
Score: 0.39 0.06 0.33 0.786
P-value: 8.618E-01 (transcription from Pol I promoter) 1.069E+00 (protein binding) 4.028E-01 (endoplasmic reticulum membrane) 5.533E-08 (REB1)

REB1(1) AND ALPHA1'(1) AND SWI5(1) AND SCB(1) => SimExpr(YPL237W) OR SimExpr(other) : 6 1

EXPR: (0.167) ALPHA1' (P < 0.000) SWI5 (P < 0.002) REB1 (P < 0.002) SCB (P < 0.001)

ORF SYMBOL P F C TF
YDL232W OST4 N-linked glycosylation ->
biosynthesis, protein metabolism dolichyl-diphospho-oligosaccharide-protein glycosyltransferase activity, protein binding\, bridging ->
dolichyl-diphospho-oligosaccharide-protein glycosyltransferase activity, protein binding\, bridging endoplasmic reticulum membrane ->
cytoplasm, endomembrane system REB1
YPL237W SUI3 translational initiation ->
biosynthesis, protein metabolism translation initiation factor activity ->
translation initiation factor activity ribosome ->
cytoplasm, ribonucleoprotein complex
YMR121C RPL15B protein biosynthesis ->
biosynthesis, protein metabolism RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex REB1
YNL111C CYB5 sterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism electron transporter activity ->
electron transporter activity microsome ->
membrane fraction ABF1, GCR2, GTS1, NRG1, REB1, ROX1
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding nucleolus ->
nucleus
YOL006C TOP1 negative regulation of recombination within rDNA repeats, DNA topological change, DNA strand elongation, chromatin assembly/disassembly, regulation of transcription from Pol II promoter, RNA elongation from Pol II promoter, mitotic chromosome condensation, nuclear migration ->
cell organization and biogenesis, cell cycle, mitotic cell cycle, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DNA topoisomerase type I activity ->
DNA topoisomerase type I activity nucleus ->
nucleus REB1
|YMR002W| NO SYMBOL NDD1, REB1, SWI6
Main: biosynthesis (0.67) RNA binding (0.33) cytoplasm (0.50) REB1 (1.00)
Score: 0.47 0.07 0.27 1.000
P-value: 4.689E-01 (protein biosynthesis) 5.219E-01 (RNA binding) 8.041E-01 (ribosome) 8.614E-06 (REB1)

REB1(1) AND ALPHA1'(1) AND SFF'(1) AND SWI5(1) AND SCB(1) => SimExpr(YPL237W) : 6

REB1(1) AND SFF'(1) AND SWI5(1) AND SCB(1) => SimExpr(YDL232W) OR SimExpr(other) : 6 1

EXPR: (0.141) SFF' (P < 0.000) SWI5 (P < 0.001) REB1 (P < 0.007) SCB (P < 0.004)

ORF SYMBOL P F C TF
YDL232W OST4 N-linked glycosylation ->
biosynthesis, protein metabolism dolichyl-diphospho-oligosaccharide-protein glycosyltransferase activity, protein binding\, bridging ->
dolichyl-diphospho-oligosaccharide-protein glycosyltransferase activity, protein binding\, bridging endoplasmic reticulum membrane ->
cytoplasm, endomembrane system REB1
YPL237W SUI3 translational initiation ->
biosynthesis, protein metabolism translation initiation factor activity ->
translation initiation factor activity ribosome ->
cytoplasm, ribonucleoprotein complex
YMR121C RPL15B protein biosynthesis ->
biosynthesis, protein metabolism RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex REB1
YNL111C CYB5 sterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism electron transporter activity ->
electron transporter activity microsome ->
membrane fraction ABF1, GCR2, GTS1, NRG1, REB1, ROX1
|YMR186W| HSC82 protein folding, response to stress ->
protein metabolism, response to stress cation-transporting ATPase activity, chaperone activity ->
cation-transporting ATPase activity, chaperone activity BAS1, HAP2, HSF1, INO4, REB1, ROX1
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding nucleolus ->
nucleus
YOL006C TOP1 negative regulation of recombination within rDNA repeats, DNA topological change, DNA strand elongation, chromatin assembly/disassembly, regulation of transcription from Pol II promoter, RNA elongation from Pol II promoter, mitotic chromosome condensation, nuclear migration ->
cell organization and biogenesis, cell cycle, mitotic cell cycle, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DNA topoisomerase type I activity ->
DNA topoisomerase type I activity nucleus ->
nucleus REB1
Main: biosynthesis (0.57) RNA binding (0.29) cytoplasm (0.50) REB1 (1.00)
Score: 0.48 0.05 0.27 1.000
P-value: 4.689E-01 (protein biosynthesis) 2.080E-01 (binding) 8.041E-01 (ribosome) 1.077E-05 (REB1)

REB1(1) AND SFF(1) AND SWI5(1) AND SCB(1) => SimExpr(YDL232W) OR SimExpr(other) : 5 1

EXPR: (0.147) SFF (P < 0.001) SWI5 (P < 0.003) REB1 (P < 0.007) SCB (P < 0.007)

ORF SYMBOL P F C TF
YDL232W OST4 N-linked glycosylation ->
biosynthesis, protein metabolism dolichyl-diphospho-oligosaccharide-protein glycosyltransferase activity, protein binding\, bridging ->
dolichyl-diphospho-oligosaccharide-protein glycosyltransferase activity, protein binding\, bridging endoplasmic reticulum membrane ->
cytoplasm, endomembrane system REB1
YMR121C RPL15B protein biosynthesis ->
biosynthesis, protein metabolism RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex REB1
YNL111C CYB5 sterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism electron transporter activity ->
electron transporter activity microsome ->
membrane fraction ABF1, GCR2, GTS1, NRG1, REB1, ROX1
|YMR186W| HSC82 protein folding, response to stress ->
protein metabolism, response to stress cation-transporting ATPase activity, chaperone activity ->
cation-transporting ATPase activity, chaperone activity BAS1, HAP2, HSF1, INO4, REB1, ROX1
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding nucleolus ->
nucleus
YOL006C TOP1 negative regulation of recombination within rDNA repeats, DNA topological change, DNA strand elongation, chromatin assembly/disassembly, regulation of transcription from Pol II promoter, RNA elongation from Pol II promoter, mitotic chromosome condensation, nuclear migration ->
cell organization and biogenesis, cell cycle, mitotic cell cycle, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DNA topoisomerase type I activity ->
DNA topoisomerase type I activity nucleus ->
nucleus REB1
Main: biosynthesis (0.50) RNA binding (0.33) cytoplasm (0.40) REB1 (1.00)
Score: 0.40 0.07 0.20 1.000
P-value: 1.406E+00 (metabolism) 4.562E-01 (RNA binding) 4.023E+00 (nucleus) 3.167E-06 (REB1)

REB1(1) AND ALPHA1'(1) AND SFF'(1) AND SWI5(1) AND SCB(1) => SimExpr(YDL232W) : 6

REB1(1) AND ALPHA1'(1) AND SFF(1) AND SWI5(1) AND SCB(1) => SimExpr(YDL232W) : 5

REB1(1) AND PAC(1) => SimExpr(YOR021C) OR SimExpr(other) : 6 1

REB1(1) AND ALPHA1'(1) AND PAC(1) => SimExpr(YOR021C) : 5

Gcr1(1) AND PAC(1) => SimExpr(YOR272W) OR SimExpr(other) : 5 1

EXPR: (0.160) Gcr1 (P < 0.008) PAC (P < 0.450)

ORF SYMBOL P F C TF
|YIL122W| POG1 re-entry into mitotic cell cycle after pheromone arrest ->
regulation of cell cycle, conjugation with cellular fusion, perception of chemical substance, sensory perception specific RNA polymerase II transcription factor activity ->
specific RNA polymerase II transcription factor activity nucleus ->
nucleus ASH1, CIN5, NRG1, RLM1, SMP1, YAP6
YNR046W NO SYMBOL ABF1
YNL292W PUS4 tRNA modification ->
RNA processing, tRNA metabolism pseudouridylate synthase activity ->
pseudouridylate synthase activity mitochondrion, nucleus ->
cytoplasm, nucleus RCS1
YOR272W YTM1 chromosome organization and biogenesis (sensu Eukarya), ribosomal large subunit biogenesis ->
chromosome organization and biogenesis (sensu Eukarya), ribosome biogenesis and assembly nucleus, nucleolus ->
nucleus LEU3, PUT3, REB1
YGL029W CGR1 ribosome biogenesis, rRNA processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent nucleolus ->
nucleus
YML125C NO SYMBOL MAL13, MSN4, NDD1, RME1, SWI5
Main: RNA processing (0.50) specific RNA polymerase II transcription factor activity (0.50) nucleus (1.00) ABF1 (0.20)
Score: 0.33 0.00 1.00 0.000
P-value: 2.602E-01 (ribosome biogenesis) 2.000E+00 1.255E-01 (nucleolus) 6.908E-01 (PUT3)

REB1(1) AND PAC(1) => SimExpr(YOR272W) OR SimExpr(other) : 6 1

REB1(1) AND ALPHA1'(1) AND PAC(1) => SimExpr(YOR272W) : 5

REB1(1) AND SFF'(1) AND SWI5(1) AND SCB(1) => SimExpr(YMR121C) OR SimExpr(other) : 6 1

REB1(1) AND SFF(1) AND SWI5(1) AND SCB(1) => SimExpr(YMR121C) OR SimExpr(other) : 5 1

REB1(1) AND ALPHA1'(1) AND SFF(1) AND SWI5(1) AND SCB(1) => SimExpr(YMR121C) : 5

REB1(1) AND ALPHA1'(1) AND SFF'(1) AND SWI5(1) AND SCB(1) => SimExpr(YMR121C) : 6

RAP1(1) AND SWI5(1) => SimExpr(YJR145C) OR SimExpr(other) : 21 7

CSRE(1) AND RAP1(1) => SimExpr(YJR145C) OR SimExpr(other) : 12 2

EXPR: (0.127) CSRE (P < 0.000) RAP1 (P < 0.089)

CSRE(1) AND RAP1(1) AND SWI5(1) => SimExpr(YJR145C) : 6

EXPR: (0.059) SWI5 (P < 0.000) CSRE (P < 0.000) RAP1 (P < 0.004)

ORF SYMBOL P F C TF
YOR312C RPL20B protein biosynthesis ->
protein biosynthesis structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosolic ribosome (sensu Eukarya), large ribosomal subunit FHL1, FKH2, GAT3, RAP1
YJR145C RPS4A protein biosynthesis ->
protein biosynthesis structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya), cytoplasm ->
cytosolic ribosome (sensu Eukarya), cytoplasm, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, small ribosomal subunit ACE2, CIN5, FHL1, INO4, MTH1, RAP1, YAP6
YLR344W RPL26A protein biosynthesis ->
protein biosynthesis RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosolic ribosome (sensu Eukarya), large ribosomal subunit FHL1, RAP1
YOR213C SAS5 chromatin silencing at telomere ->
chromatin silencing at telomere acetyltransferase activity ->
acetyltransferase activity nuclear chromosome\, telomeric region, nuclear chromatin ->
nuclear chromosome\, telomeric region, nuclear chromatin GRF10(Pho2), SUM1
YDR450W RPS18A protein biosynthesis ->
protein biosynthesis structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
cytosolic ribosome (sensu Eukarya), eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, small ribosomal subunit FHL1, GAT3, HIR2, RAP1, RGM1, YAP5
YNL069C RPL16B protein biosynthesis ->
protein biosynthesis RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosolic ribosome (sensu Eukarya), large ribosomal subunit FHL1, GAT3, PDR1, RAP1, RGM1, YAP5
Main: protein biosynthesis (0.83) structural constituent of ribosome (0.83) cytosolic ribosome (sensu Eukarya) (0.83) RAP1 FHL1 (0.83)
Score: 0.67 0.67 0.67 0.667
P-value: 6.996E-04 (protein biosynthesis) 2.807E-05 (structural constituent of ribosome) 1.419E-05 (cytosolic ribosome (sensu Eukarya)) 1.685E-06 (FHL1)

ABF1(1) AND PAC(1) => SimExpr(YPR010C) OR SimExpr(other) : 11 5

EXPR: (0.176) ABF1 (P < 0.000) PAC (P < 0.009)

ORF SYMBOL P F C TF
|YLR197W| SIK1 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex, nucleus, nucleolus ->
nucleus, ribonucleoprotein complex DAL81, HAL9
|YHR027C| RPN1 ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism endopeptidase activity, receptor activity ->
peptidase activity, receptor activity proteasome regulatory particle (sensu Eukarya), endoplasmic reticulum, cytoplasm ->
cytoplasm, nucleus
YOL041C NOP12 rRNA metabolism ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding nucleolus ->
nucleus GTS1, MET31
YJL050W MTR4 35S primary transcript processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus
YNR046W NO SYMBOL ABF1
|YNL292W| PUS4 tRNA modification ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism pseudouridylate synthase activity ->
carbon-oxygen lyase activity mitochondrion, nucleus ->
cytoplasm, nucleus RCS1
YNL112W DBP2 RNA helicase activity ->
RNA binding bud neck ->
site of polarized growth (sensu Fungi)
|YGR187C| HGH1 ABF1, HAP3, HIR1, RCS1, RTG1
YDR527W NO SYMBOL ABF1, SKN7
|YKL172W| EBP2 rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism nucleolus ->
nucleus ABF1, FZF1, RFX1
YGR283C NO SYMBOL ACE2, RAP1, SMP1
YKL078W DHR2 ribosome biogenesis ->
cell organization and biogenesis RNA helicase activity ->
RNA binding nucleolus ->
nucleus ABF1
YPR010C RPA135 transcription from Pol I promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DNA-directed RNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups DNA-directed RNA polymerase I complex ->
nucleus ROX1, SIG1
YJL069C UTP18 ABF1
YKL014C NO SYMBOL ABF1
YDR312W SSF2 ribosomal large subunit assembly and maintenance, conjugation with cellular fusion ->
cell organization and biogenesis, conjugation, sexual reproduction rRNA binding ->
RNA binding nucleolus ->
nucleus ABF1, FKH2, INO4, RAP1
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.67) RNA binding (0.62) nucleus (0.90) ABF1 (0.62)
Score: 0.61 0.36 0.80 0.385
P-value: 1.075E-02 (ribosome biogenesis and assembly) 3.026E-03 (RNA helicase activity) 6.686E-06 (nucleolus) 5.587E-05 (ABF1)

mRRPE(1) AND PAC(1) => SimExpr(YOR310C) OR SimExpr(other) : 75 10

mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YOR310C) OR SimExpr(other) : 20 2

mRRPE(1) AND SWI5(1) AND PAC(1) => SimExpr(YOR310C) OR SimExpr(other) : 14 3

EXPR: (0.136) mRRPE (P < 0.002) SWI5 (P < 0.000) PAC (P < 0.072)

mRRPE(1) AND PAC(1) AND MCM1'(1) => SimExpr(YOR310C) OR SimExpr(other) : 13 4

EXPR: (0.133) mRRPE (P < 0.002) PAC (P < 0.045) MCM1' (P < 0.000)

mRRPE(1) AND SWI5(1) AND PAC(1) AND SCB(1) => SimExpr(YOR310C) : 6

EXPR: (0.068) mRRPE (P < 0.000) SWI5 (P < 0.000) PAC (P < 0.002) SCB (P < 0.001)

ALPHA1'(1) AND SFF(1) AND PDR(1) AND SWI5(1) => SimExpr(YLR152C) OR SimExpr(other) : 7 3

EXPR: (0.160) ALPHA1' (P < 0.000) SFF (P < 0.000) PDR (P < 0.000) SWI5 (P < 0.000)

ORF SYMBOL P F C TF
YNL144C NO SYMBOL RAP1
YNL033W NO SYMBOL GAT1, MAL13
YNL019C NO SYMBOL
|YPR036W| VMA13 vacuolar acidification ->
cell homeostasis, cell organization and biogenesis, transport hydrogen-exporting ATPase activity ->
hydrogen-exporting ATPase activity hydrogen-transporting ATPase V1 domain, vacuolar membrane (sensu Fungi) ->
hydrogen-transporting ATPase V1 domain, vacuolar membrane (sensu Fungi)
|YGR287C| NO SYMBOL
YOL159C NO SYMBOL ARO80, CIN5, RLM1
YDR343C HXT6 hexose transport ->
transport glucose transporter activity, fructose transporter activity, mannose transporter activity ->
glucose transporter activity, fructose transporter activity, mannose transporter activity plasma membrane ->
plasma membrane CIN5, INO4, NRG1, PHD1
YJR155W AAD10 aldehyde metabolism ->
aldehyde metabolism benzyl alcohol dehydrogenase activity ->
benzyl alcohol dehydrogenase activity
YLR152C NO SYMBOL GRF10(Pho2), PHO4, PUT3
|YFR022W| NO SYMBOL
Main: transport (0.67) hydrogen-exporting ATPase activity (0.33) vacuolar membrane (sensu Fungi) (0.50) CIN5 (0.40)
Score: 0.33 0.00 0.00 0.100
P-value: 3.919E+00 (transport) 1.443E+00 (transporter activity) 2.912E+00 (membrane) 8.516E-01 (PUT3)

LYS14(1) AND SFF(1) AND SFF'(1) AND ATRepeat(1) => SimExpr(YKL077W) OR SimExpr(other) : 7 3

EXPR: (0.187) LYS14 (P < 0.003) SFF (P < 0.007) SFF' (P < 0.007) ATRepeat (P < 0.000)

ORF SYMBOL P F C TF
|YNL122C| NO SYMBOL ARO80
YKL077W NO SYMBOL CHA4, GCR1, HAP3, HIR1, IXR1, REB1, STP1
YMR321C NO SYMBOL
YKL054C DEF1 response to DNA damage, ubiquitin-dependent protein catabolism ->
response to biotic stimulus, catabolism, protein metabolism nucleus ->
nucleus
YBR115C LYS2 lysine biosynthesis\, aminoadipic pathway ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis aminoadipate-semialdehyde dehydrogenase activity ->
oxidoreductase activity\, acting on the aldehyde or oxo group of donors cytoplasm ->
cytoplasm DAL81, GCN4
YKL152C GPM1 gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism phosphoglycerate mutase activity ->
intramolecular transferase activity cytosol ->
cytoplasm GCR1, GCR2, HSF1, RAP1
YNL102W POL1 DNA replication\, priming, DNA replication initiation, lagging strand elongation, DNA repair synthesis ->
DNA metabolism, cell proliferation alpha DNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups alpha DNA polymerase\:primase complex ->
nucleus LEU3, MBP1
|YOR348C| PUT4 neutral amino acid transport ->
transport amino acid permease activity, neutral amino acid transporter activity ->
carboxylic acid transporter activity, polyamine transporter activity, electrochemical potential-driven transporter activity plasma membrane ->
plasma membrane SWI5
YDR226W ADK1 cell proliferation ->
cell proliferation adenylate kinase activity ->
transferase activity\, transferring phosphorus-containing groups cytoplasm, mitochondrial intermembrane space ->
cytoplasm PUT3
|YNL246W| VPS75 protein-vacuolar targeting ->
cell organization and biogenesis, protein metabolism, transport AZF1, SIG1, STP2
Main: biosynthesis (0.29) transferase activity\, transferring phosphorus-containing groups (0.40) cytoplasm (0.50) GCR1 (0.25)
Score: 0.24 0.10 0.27 0.036
P-value: 2.148E+00 (catabolism) 1.072E+00 (transferase activity\, transferring phosphorus-containing groups) 5.453E+00 (nucleus) 9.644E-02 (GCR1)

CSRE(1) AND RAP1(1) => SimExpr(YOR312C) OR SimExpr(other) : 12 2

CSRE(1) AND RAP1(1) AND SWI5(1) => SimExpr(YOR312C) : 6

PAC(1) AND MCM1'(1) AND SCB(1) => SimExpr(YDR399W) OR SimExpr(other) : 8 3

EXPR: (0.178) PAC (P < 0.384) MCM1' (P < 0.001) SCB (P < 0.008)

ORF SYMBOL P F C TF
YGR159C NSR1 ribosomal small subunit assembly and maintenance, rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism single-stranded DNA binding, RNA binding ->
DNA binding, RNA binding nucleolus, nucleus ->
intracellular
YIL118W RHO3 exocytosis, small GTPase mediated signal transduction, establishment of cell polarity (sensu Saccharomyces), actin filament organization ->
signal transduction, cell organization and biogenesis, transport Rho small monomeric GTPase activity, signal transducer activity ->
purine nucleotide binding, signal transducer activity, hydrolase activity\, acting on acid anhydrides intracellular ->
intracellular CIN5, NRG1, PHD1, SKN7, SOK2, YAP6
YDR399W HPT1 purine nucleotide biosynthesis ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism hypoxanthine phosphoribosyltransferase activity ->
transferase activity\, transferring glycosyl groups
YIL066C RNR3 DNA replication ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ribonucleoside-diphosphate reductase activity ->
oxidoreductase activity\, acting on CH2 groups cytoplasm ->
intracellular RFX1, STB1
YBR034C HMT1 peptidyl-arginine modification, mRNA-nucleus export ->
protein metabolism, transport, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism protein-arginine N-methyltransferase activity ->
transferase activity\, transferring one-carbon groups nucleus ->
intracellular
|YBL099W| ATP1 ATP synthesis coupled proton transport ->
transport hydrogen-transporting ATP synthase activity ->
cation transporter activity proton-transporting ATP synthase\, catalytic core (sensu Eukarya) ->
intracellular, integral to membrane, inner membrane HAP4, ROX1
|YIL099W| SGA1 sporulation (sensu Saccharomyces) ->
sporulation glucan 1\,4-alpha-glucosidase activity ->
hydrolase activity\, acting on glycosyl bonds vacuole (sensu Fungi) ->
intracellular ASH1, CIN5, CUP9, MOT3, NRG1, PHD1, ROX1, SKN7, SOK2, YAP6
YOR310C NOP58 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex ->
intracellular ABF1, SWI6
|YLL010C| PSR1 response to stress ->
response to stress protein phosphatase activity ->
hydrolase activity\, acting on ester bonds plasma membrane ->
plasma membrane CBF1
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding nucleolus ->
intracellular
YGR158C MTR3 35S primary transcript processing, mRNA catabolism ->
cell organization and biogenesis, catabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism 3'-5' exoribonuclease activity ->
hydrolase activity\, acting on ester bonds, RNA binding nuclear exosome (RNase complex), cytoplasmic exosome (RNase complex) ->
intracellular ZMS1
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.64) RNA binding (0.30) intracellular (0.90) SOK2 SKN7 YAP6 CIN5 ROX1 PHD1 NRG1 (0.29)
Score: 0.51 0.09 0.80 0.095
P-value: 3.549E-03 (rRNA processing) 3.645E-01 (RNA binding) 6.237E-02 (nucleolus) 2.918E-01 (SOK2)

mRRPE(1) AND PAC(1) => SimExpr(YDR399W) OR SimExpr(other) : 75 10

SWI5(1) AND PAC(1) AND SCB(1) => SimExpr(YDR399W) OR SimExpr(other) : 9 3

mRRPE(1) AND PAC(1) AND MCM1'(1) => SimExpr(YDR399W) OR SimExpr(other) : 13 4

mRRPE(1) AND MCM1'(1) AND ALPHA2'(1) => SimExpr(YDR399W) OR SimExpr(other) : 5 1

EXPR: (0.110) mRRPE (P < 0.014) MCM1' (P < 0.000) ALPHA2' (P < 0.000)

ORF SYMBOL P F C TF
YJR025C BNA1 nicotinamide adenine dinucleotide biosynthesis ->
coenzymes and prosthetic group metabolism, biosynthesis, water-soluble vitamin metabolism, vitamin metabolism 3-hydroxyanthranilate 3\,4-dioxygenase activity ->
3-hydroxyanthranilate 3\,4-dioxygenase activity cytoplasm ->
cytoplasm GCN4, SUM1, SWI6
YDR399W HPT1 purine nucleotide biosynthesis ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism hypoxanthine phosphoribosyltransferase activity ->
hypoxanthine phosphoribosyltransferase activity
YBL092W RPL32 protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, RAP1
|YOR095C| RKI1 pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism ribose-5-phosphate isomerase activity ->
ribose-5-phosphate isomerase activity FHL1, FKH2, RAP1
YGR001C NO SYMBOL
YDR119W NO SYMBOL MSS11, SIG1, SKO1
Main: biosynthesis (0.75) 3-hydroxyanthranilate 3\,4-dioxygenase activity (0.25) cytoplasm (1.00) RAP1 FHL1 (0.50)
Score: 0.67 0.00 1.00 0.167
P-value: 1.824E-02 (pyridine nucleotide metabolism) 2.099E+00 (enzyme activity) 4.698E+00 (cytoplasm) 1.060E-01 (FHL1)

mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YDR399W) OR SimExpr(other) : 20 2

mRRPE(1) AND SWI5(1) AND PAC(1) => SimExpr(YDR399W) OR SimExpr(other) : 14 3

SWI5(1) AND MCM1'(1) AND ALPHA2'(1) => SimExpr(YDR399W) : 6

EXPR: (0.123) SWI5 (P < 0.000) MCM1' (P < 0.000) ALPHA2' (P < 0.002)

ORF SYMBOL P F C TF
YJR025C BNA1 nicotinamide adenine dinucleotide biosynthesis ->
coenzymes and prosthetic group metabolism, biosynthesis, water-soluble vitamin metabolism, vitamin metabolism 3-hydroxyanthranilate 3\,4-dioxygenase activity ->
3-hydroxyanthranilate 3\,4-dioxygenase activity cytoplasm ->
cytoplasm GCN4, SUM1, SWI6
YDR399W HPT1 purine nucleotide biosynthesis ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism hypoxanthine phosphoribosyltransferase activity ->
hypoxanthine phosphoribosyltransferase activity
YOR109W INP53 endocytosis, dephosphorylation, cell wall organization and biogenesis ->
transport, phosphorus metabolism, cell organization and biogenesis inositol-1\,4\,5-trisphosphate 5-phosphatase activity ->
inositol-1\,4\,5-trisphosphate 5-phosphatase activity actin cortical patch (sensu Saccharomyces), membrane fraction ->
cell cortex, membrane fraction, cytoplasm SIP4
YPL028W ERG10 ergosterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism acetyl-CoA C-acetyltransferase activity ->
acetyl-CoA C-acetyltransferase activity cytosol ->
cytoplasm MTH1
YGL034C NO SYMBOL
YGR001C NO SYMBOL
Main: biosynthesis (0.75) 3-hydroxyanthranilate 3\,4-dioxygenase activity (0.25) cytoplasm (1.00) MTH1 (0.33)
Score: 0.50 0.00 1.00 0.000
P-value: 5.570E-01 (biosynthesis) 1.001E+00 (transferase activity) 3.832E+00 (cytoplasm) 5.012E-01 (SIP4)

mRRPE(1) AND SWI5(1) AND PAC(1) AND SCB(1) => SimExpr(YDR399W) : 6

ALPHA1(1) AND mRRPE(1) AND ALPHA2'(1) => SimExpr(YLR355C) : 6

EXPR: (0.109) mRRPE (P < 0.010) ALPHA2' (P < 0.000) ALPHA1 (P < 0.000)

ORF SYMBOL P F C TF
YPR117W NO SYMBOL IME4, MBP1, SFP1
YGR094W VAS1 valyl-tRNA aminoacylation ->
biosynthesis, protein metabolism valine-tRNA ligase activity ->
valine-tRNA ligase activity cytoplasm, mitochondrion ->
cytoplasm SIG1
YLR355C ILV5 branched chain family amino acid biosynthesis, mitochondrial genome maintenance ->
amine metabolism, cell organization and biogenesis, amino acid and derivative metabolism, organic acid metabolism, biosynthesis ketol-acid reductoisomerase activity ->
ketol-acid reductoisomerase activity mitochondrion ->
cytoplasm GCN4, MET4
YBL092W RPL32 protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, RAP1
YOR095C RKI1 pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism ribose-5-phosphate isomerase activity ->
ribose-5-phosphate isomerase activity FHL1, FKH2, RAP1
YGR001C NO SYMBOL
Main: biosynthesis (0.75) structural constituent of ribosome (0.25) cytoplasm (1.00) RAP1 FHL1 (0.40)
Score: 0.50 0.00 1.00 0.100
P-value: 8.913E-01 (biosynthesis) 2.099E+00 (enzyme activity) 1.070E+00 (mitochondrion) 1.060E-01 (FHL1)

LYS14(1) AND PAC(1) => SimExpr(YBR034C) OR SimExpr(other) : 14 5

ALPHA1(1) AND PAC(1) => SimExpr(YBR034C) OR SimExpr(other) : 44 15

EXPR: (0.175) PAC (P < 0.487) ALPHA1 (P < 0.000)

ALPHA1(1) AND PAC(1) AND SCB(1) => SimExpr(YBR034C) OR SimExpr(other) : 18 3

EXPR: (0.125) PAC (P < 0.009) SCB (P < 0.000) ALPHA1 (P < 0.000)

LYS14(1) AND PAC(1) AND SCB(1) => SimExpr(YBR034C) OR SimExpr(other) : 7 2

EXPR: (0.136) LYS14 (P < 0.000) PAC (P < 0.168) SCB (P < 0.000)

CSRE(1) AND RAP1(1) => SimExpr(YDR450W) OR SimExpr(other) : 12 2

RAP1(1) AND MCM1'(1) => SimExpr(YDR450W) OR SimExpr(other) : 17 6

RAP1(1) AND SWI5(1) => SimExpr(YDR450W) OR SimExpr(other) : 21 7

CSRE(1) AND RAP1(1) AND SWI5(1) => SimExpr(YDR450W) : 6

RAP1(1) AND SWI5(1) AND MCM1'(1) => SimExpr(YDR450W) : 7

mRRPE(1) AND PAC(1) => SimExpr(YGR159C) OR SimExpr(other) : 79 6

mRRPE(1) AND PAC(1) AND MCM1'(1) => SimExpr(YGR159C) OR SimExpr(other) : 14 3

CSRE(1) AND mRRPE(1) AND PAC(1) => SimExpr(YGR159C) : 5

EXPR: (0.090) mRRPE (P < 0.010) PAC (P < 0.084) CSRE (P < 0.000)

CSRE(1) AND mRRPE(1) AND PAC(1) => SimExpr(YGR245C) : 5

RAP1(1) => SimExpr(YDL043C) OR SimExpr(other) : 53 25

EXPR: (0.198) RAP1 (P < 0.657)

CSRE(1) AND RAP1(1) => SimExpr(YDL043C) OR SimExpr(other) : 12 2

RAP1(1) AND SFF(1) => SimExpr(YDL043C) OR SimExpr(other) : 35 13

EXPR: (0.177) SFF (P < 0.000) RAP1 (P < 0.104)

RAP1(1) AND ALPHA1'(1) => SimExpr(YDL043C) OR SimExpr(other) : 30 11

RAP1(1) AND ALPHA2(1) => SimExpr(YDL043C) OR SimExpr(other) : 9 3

EXPR: (0.180) ALPHA2 (P < 0.000) RAP1 (P < 0.312)

SFF(1) AND mRRPE(1) AND zap1(1) => SimExpr(YNL189W) OR SimExpr(other) : 5 2

EXPR: (0.212) SFF (P < 0.033) mRRPE (P < 0.349) zap1 (P < 0.041)

ORF SYMBOL P F C TF
YNL189W SRP1 nucleocytoplasmic transport ->
transport protein carrier activity ->
protein carrier activity nucleus, cytoplasm ->
nucleus, cytoplasm ABF1, MOT3
YPR117W NO SYMBOL IME4, MBP1, SFP1
YKR079C NO SYMBOL BAS1
YLR130C ZRT2 low-affinity zinc ion transport ->
transport low-affinity zinc ion transporter activity ->
low-affinity zinc ion transporter activity plasma membrane ->
plasma membrane ZAP1
YMR130W NO SYMBOL
|YCR044C| PER1 manganese ion homeostasis, response to unfolded protein ->
response to biotic stimulus, cell homeostasis vacuolar membrane (sensu Fungi) ->
cytoplasm, vacuole YFL044C
|YJR122W| CAF17 YAP1
Main: transport (0.67) low-affinity zinc ion transporter activity (0.50) cytoplasm (0.67) ABF1 (0.17)
Score: 0.33 0.00 0.33 0.000
P-value: 2.699E+00 (transport) 6.419E-01 (transporter activity) 3.145E+00 (membrane) 5.564E-01 (ZAP1)

SFF'(1) AND mRRPE(1) AND zap1(1) => SimExpr(YNL189W) OR SimExpr(other) : 7 1

EXPR: (0.159) SFF' (P < 0.002) mRRPE (P < 0.051) zap1 (P < 0.002)

ORF SYMBOL P F C TF
YNL189W SRP1 nucleocytoplasmic transport ->
transport protein carrier activity ->
protein carrier activity nucleus, cytoplasm ->
nucleus, cytoplasm ABF1, MOT3
YPR117W NO SYMBOL IME4, MBP1, SFP1
YKR079C NO SYMBOL BAS1
YKR059W TIF1 translational initiation ->
biosynthesis, protein metabolism translation initiation factor activity ->
translation initiation factor activity ribosome ->
cytoplasm, ribonucleoprotein complex ABF1, FKH1, FKH2
YLR130C ZRT2 low-affinity zinc ion transport ->
transport low-affinity zinc ion transporter activity ->
low-affinity zinc ion transporter activity plasma membrane ->
plasma membrane ZAP1
YMR130W NO SYMBOL
YLR355C ILV5 branched chain family amino acid biosynthesis, mitochondrial genome maintenance ->
amine metabolism, cell organization and biogenesis, amino acid and derivative metabolism, organic acid metabolism, biosynthesis ketol-acid reductoisomerase activity ->
ketol-acid reductoisomerase activity mitochondrion ->
cytoplasm GCN4, MET4
|YJR122W| CAF17 YAP1
Main: biosynthesis (0.50) low-affinity zinc ion transporter activity (0.25) cytoplasm (0.75) ABF1 (0.29)
Score: 0.33 0.00 0.50 0.048
P-value: 4.199E+00 (transport) 1.052E+00 (transporter activity) 4.619E+00 (cytoplasm) 8.442E-01 (ZAP1)

RAP1(1) AND ATRepeat(1) => SimExpr(YKL152C) OR SimExpr(other) : 5 2

RAP1(1) AND STRE(1) => SimExpr(YGR214W) : 5

CSRE(1) AND RAP1(1) AND SWI5(1) => SimExpr(YOR213C) : 6

RAP1(1) AND ALPHA1'(1) AND SFF(1) => SimExpr(YOR096W) OR SimExpr(other) : 19 4

EXPR: (0.152) ALPHA1' (P < 0.000) SFF (P < 0.000) RAP1 (P < 0.074)

CSRE(1) AND RAP1(1) => SimExpr(YNL069C) OR SimExpr(other) : 12 2

RAP1(1) AND MCM1'(1) => SimExpr(YNL069C) OR SimExpr(other) : 17 6

RAP1(1) AND SWI5(1) => SimExpr(YNL069C) OR SimExpr(other) : 21 7

CSRE(1) AND RAP1(1) AND SWI5(1) => SimExpr(YNL069C) : 6

RAP1(1) AND SWI5(1) AND MCM1'(1) => SimExpr(YNL069C) : 7

RAP1(1) AND SCB(1) => SimExpr(YLR344W) OR SimExpr(other) : 10 4

EXPR: (0.138) SCB (P < 0.000) RAP1 (P < 0.124)

RAP1(1) AND MCM1'(1) => SimExpr(YLR344W) OR SimExpr(other) : 17 6

RAP1(1) AND ALPHA1'(1) => SimExpr(YLR344W) OR SimExpr(other) : 29 12

RAP1(1) AND SWI5(1) => SimExpr(YLR344W) OR SimExpr(other) : 20 8

CSRE(1) AND RAP1(1) => SimExpr(YLR344W) OR SimExpr(other) : 12 2

CSRE(1) AND RAP1(1) AND SWI5(1) => SimExpr(YLR344W) : 6

RAP1(1) AND SWI5(1) AND MCM1'(1) => SimExpr(YLR344W) : 7

RAP1(1) AND ALPHA1'(1) AND SFF'(1) AND SCB(1) => SimExpr(YLR344W) : 6

EXPR: (0.093) ALPHA1' (P < 0.000) SFF' (P < 0.000) SCB (P < 0.000) RAP1 (P < 0.027)

RAP1(1) AND ALPHA1'(1) AND SFF(1) AND SCB(1) => SimExpr(YLR344W) : 5

EXPR: (0.077) ALPHA1' (P < 0.000) SFF (P < 0.000) SCB (P < 0.000) RAP1 (P < 0.010)

RPN4(1) AND MCM1'(1) AND SCB(1) => SimExpr(YJL045W) : 5

ALPHA1(1) AND ALPHA2(1) AND ALPHA1'(1) AND SWI5(1) AND SCB(1) => SimExpr(YKL209C) OR SimExpr(other) : 6 1

EXPR: (0.184) ALPHA2 (P < 0.000) ALPHA1' (P < 0.000) SWI5 (P < 0.002) SCB (P < 0.003) ALPHA1 (P < 0.001)

ORF SYMBOL P F C TF
YLR272C YCS4 mitotic chromosome condensation ->
cell proliferation, cell cycle nuclear condensin complex ->
nuclear condensin complex
YHR046C INM1 myo-inositol metabolism ->
alcohol metabolism, carbohydrate metabolism myo-inositol-1(or 4)-monophosphatase activity ->
myo-inositol-1(or 4)-monophosphatase activity
YPR195C NO SYMBOL FKH1, FKH2, HIR1, HIR2, INO4, RLM1
YKL209C STE6 peptide pheromone export ->
transport ATP-binding cassette (ABC) transporter activity ->
ATP-binding cassette (ABC) transporter activity integral to plasma membrane, shmoo tip ->
integral to plasma membrane, shmoo tip MCM1, STE12
|YOR111W| NO SYMBOL UGA3
YNL111C CYB5 sterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism electron transporter activity ->
electron transporter activity microsome ->
microsome ABF1, GCR2, GTS1, NRG1, REB1, ROX1
YGR001C NO SYMBOL
Main: alcohol metabolism (0.50) electron transporter activity (0.33) integral to plasma membrane (0.33) GCR2 (0.25)
Score: 0.17 0.00 0.00 0.000
P-value: 2.701E-01 (alcohol metabolism) 1.070E+00 (transporter activity) 3.000E+00 (cell) 1.000E+00

SFF'(1) AND mRRPE(1) AND zap1(1) => SimExpr(YLR130C) OR SimExpr(other) : 6 2

ALPHA1(1) AND ALPHA2(1) AND ALPHA1'(1) AND MCM1'(1) AND SCB(1) => SimExpr(YLR084C) OR SimExpr(other) : 6 2

EXPR: (0.177) ALPHA2 (P < 0.009) ALPHA1' (P < 0.006) MCM1' (P < 0.001) SCB (P < 0.024) ALPHA1 (P < 0.004)

ORF SYMBOL P F C TF
YLR084C RAX2 bud site selection ->
establishment of cell polarity (sensu Saccharomyces), cytokinesis\, site selection bud neck, bud scar, membrane ->
site of polarized growth (sensu Fungi), cell wall, membrane FKH2, MCM1, NDD1, SKN7, SWI4
|YCL047C| NO SYMBOL CIN5
YHR046C INM1 myo-inositol metabolism ->
myo-inositol metabolism myo-inositol-1(or 4)-monophosphatase activity ->
myo-inositol-1(or 4)-monophosphatase activity
YNL271C BNI1 mitotic spindle orientation, response to osmotic stress, actin filament organization, bud growth, polar budding, Rho protein signal transduction, establishment of cell polarity (sensu Saccharomyces), mRNA localization\, intracellular ->
spindle assembly, response to osmotic stress, actin filament organization, bud growth, polar budding, Rho protein signal transduction, establishment of cell polarity (sensu Saccharomyces), mRNA localization\, intracellular, mitosis cytoskeletal regulatory protein binding ->
cytoskeletal regulatory protein binding polarisome, actin cap (sensu Saccharomyces) ->
cell cortex, site of polarized growth (sensu Fungi), site of polarized growth (sensu Saccharomyces), cytoplasm IME4, PHO4, SWI5
|YGR147C| NAT2 N-terminal peptidyl-methionine acetylation ->
N-terminal peptidyl-methionine acetylation peptide alpha-N-acetyltransferase activity ->
peptide alpha-N-acetyltransferase activity cytoplasm ->
cytoplasm HIR1, REB1
YPR195C NO SYMBOL FKH1, FKH2, HIR1, HIR2, INO4, RLM1
YKL209C STE6 peptide pheromone export ->
peptide pheromone export ATP-binding cassette (ABC) transporter activity ->
ATP-binding cassette (ABC) transporter activity integral to plasma membrane, shmoo tip ->
site of polarized growth (sensu Fungi), membrane MCM1, STE12
YGR001C NO SYMBOL
Main: establishment of cell polarity (sensu Saccharomyces) (0.40) peptide alpha-N-acetyltransferase activity (0.25) site of polarized growth (sensu Fungi) (0.75) FKH2 MCM1 HIR1 (0.33)
Score: 0.10 0.00 0.67 0.200
P-value: 1.697E-01 (establishment of cell polarity (sensu Fungi)) 2.351E+00 (hydrolase activity) 2.067E-02 (site of polarized growth (sensu Saccharomyces)) 1.297E-01 (HIR1)

ALPHA1(1) AND CCA(1) AND MCM1'(1) AND SCB(1) => SimExpr(YLR084C) OR SimExpr(other) : 5 2

EXPR: (0.191) CCA (P < 0.003) MCM1' (P < 0.008) SCB (P < 0.034) ALPHA1 (P < 0.022)

ORF SYMBOL P F C TF
YLR084C RAX2 bud site selection ->
cell proliferation, cell organization and biogenesis bud neck, bud scar, membrane ->
site of polarized growth (sensu Fungi), cell wall, membrane FKH2, MCM1, NDD1, SKN7, SWI4
YIL118W RHO3 exocytosis, small GTPase mediated signal transduction, establishment of cell polarity (sensu Saccharomyces), actin filament organization ->
signal transduction, cell organization and biogenesis, transport Rho small monomeric GTPase activity, signal transducer activity ->
Rho small monomeric GTPase activity, signal transducer activity intracellular ->
intracellular CIN5, NRG1, PHD1, SKN7, SOK2, YAP6
|YGR157W| CHO2 phosphatidylcholine biosynthesis ->
biosynthesis, lipid metabolism phosphatidylethanolamine N-methyltransferase activity ->
phosphatidylethanolamine N-methyltransferase activity endoplasmic reticulum ->
intracellular DAL81, INO2, INO4, MET4, SFL1
YKL185W ASH1 regulation of transcription\, mating-type specific, pseudohyphal growth ->
mating-type determination, cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism specific transcriptional repressor activity ->
specific transcriptional repressor activity nucleus ->
intracellular SMP1, SWI5
|YPL060W| LPE10 mitochondrial magnesium ion transport ->
transport magnesium ion transporter activity ->
magnesium ion transporter activity mitochondrial inner membrane ->
intracellular, membrane HIR2
YKL190W CNB1 cell ion homeostasis, cell wall organization and biogenesis, adaptation to pheromone during conjugation with cellular fusion ->
cell homeostasis, cell organization and biogenesis, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus calcium-dependent protein serine/threonine phosphatase activity ->
calcium-dependent protein serine/threonine phosphatase activity cytoplasm ->
intracellular ABF1
YNL065W AQR1 drug transport, monocarboxylic acid transport ->
transport, organic acid transport, response to abiotic stimulus monocarboxylic acid transporter activity, drug transporter activity ->
monocarboxylic acid transporter activity, drug transporter activity plasma membrane ->
membrane MET4
Main: cell organization and biogenesis (0.57) magnesium ion transporter activity (0.17) intracellular (0.71) SKN7 MET4 (0.29)
Score: 0.48 0.00 0.62 0.095
P-value: 1.592E-01 (establishment of cell polarity (sensu Fungi)) 1.758E-01 (ion transporter activity) 1.308E+00 (membrane) 7.975E-02 (MET4)

BAS1(1) AND PAC(1) => SimExpr(YIL066C) OR SimExpr(other) : 7 2

EXPR: (0.120) BAS1 (P < 0.000) PAC (P < 0.096)

ORF SYMBOL P F C TF
YIL066C RNR3 DNA replication ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ribonucleoside-diphosphate reductase activity ->
ribonucleoside-diphosphate reductase activity cytoplasm ->
cytoplasm RFX1, STB1
YNR024W NO SYMBOL
YMR049C ERB1 rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RTG3
YCL059C KRR1 ribosome biogenesis, rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism nucleolus ->
nucleus
|YCR090C| NO SYMBOL
|YBR104W| YMC2 transport ->
transport transporter activity ->
transporter activity mitochondrial inner membrane ->
cytoplasm, inner membrane FKH1, FKH2
YBR069C TAT1 amino acid transport ->
transport transporter activity ->
transporter activity plasma membrane ->
plasma membrane CIN5, DAL81, PHD1, SWI4
YOL022C NO SYMBOL MAC1, MOT3, RTS2
YLR276C DBP9 ribosomal large subunit assembly and maintenance, 35S primary transcript processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ATP dependent RNA helicase activity ->
ATP dependent RNA helicase activity nucleolus ->
nucleus MATa1, RCS1, RTG3, SWI5
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.67) transporter activity (0.50) cytoplasm (0.40) RTG3 (0.33)
Score: 0.47 0.17 0.20 0.067
P-value: 3.172E-02 (rRNA processing) 1.249E+00 (transporter activity) 3.718E-01 (nucleolus) 9.163E-02 (RTG3)

ABF1(1) AND ALPHA1'(1) AND SFF'(1) AND SCB(1) => SimExpr(YPL242C) OR SimExpr(other) : 13 6

EXPR: (0.204) ABF1 (P < 0.036) ALPHA1' (P < 0.009) SFF' (P < 0.002) SCB (P < 0.025)

ABF1(1) AND ALPHA1'(1) AND SFF(1) AND SFF'(1) AND SCB(1) => SimExpr(YPL242C) OR SimExpr(other) : 11 5

EXPR: (0.205) ABF1 (P < 0.048) ALPHA1' (P < 0.015) SFF (P < 0.011) SFF' (P < 0.010) SCB (P < 0.050)

ALPHA1(1) AND ALPHA2(1) AND SWI5(1) AND SCB(1) => SimExpr(YHR046C) OR SimExpr(other) : 11 3

ALPHA1(1) AND ALPHA2(1) AND ALPHA1'(1) AND SWI5(1) AND SCB(1) => SimExpr(YHR046C) OR SimExpr(other) : 6 1

LYS14(1) AND SFF(1) AND mRRPE(1) AND SCB(1) => SimExpr(YPR074C) : 5

EXPR: (0.139) LYS14 (P < 0.001) SFF (P < 0.000) mRRPE (P < 0.006) SCB (P < 0.001)

ALPHA1'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YGL029W) OR SimExpr(other) : 35 13

EXPR: (0.156) ALPHA1' (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.001)

ALPHA1'(1) AND SFF'(1) AND mRRPE(1) AND PAC(1) AND MCM1'(1) => SimExpr(YGL029W) OR SimExpr(other) : 5 1

EXPR: (0.148) ALPHA1' (P < 0.002) SFF' (P < 0.001) mRRPE (P < 0.033) PAC (P < 0.131) MCM1' (P < 0.000)

ORF SYMBOL P F C TF
YCR016W NO SYMBOL
YGL029W CGR1 ribosome biogenesis, rRNA processing ->
ribosome biogenesis, rRNA processing nucleolus ->
nucleolus
YOR310C NOP58 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
rRNA modification, rRNA processing small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex ->
small nuclear ribonucleoprotein complex, nucleolus, ribonucleoprotein complex ABF1, SWI6
|YDR279W| RNH202 GCR2, MBP1, RIM101, RLM1, SWI6, THI2
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
rRNA processing, snRNA processing RNA binding ->
RNA binding nucleolus ->
nucleolus
YOR095C RKI1 pentose-phosphate shunt ->
glucose catabolism, main pathways of carbohydrate metabolism, nicotinamide metabolism ribose-5-phosphate isomerase activity ->
ribose-5-phosphate isomerase activity FHL1, FKH2, RAP1
Main: rRNA processing (0.75) ribose-5-phosphate isomerase activity (0.50) nucleolus (1.00) SWI6 (0.67)
Score: 0.50 0.00 1.00 0.333
P-value: 8.043E-03 (rRNA processing) 2.000E+00 6.541E-03 (nucleolus) 1.098E-01 (SWI6)

ALPHA2(1) AND PAC(1) => SimExpr(YGL029W) OR SimExpr(other) : 17 3

ALPHA1(1) AND mRRPE(1) AND PAC(1) => SimExpr(YGL029W) OR SimExpr(other) : 20 4

EXPR: (0.135) mRRPE (P < 0.000) PAC (P < 0.001) ALPHA1 (P < 0.000)

RAP1(1) => SimExpr(YBR295W) OR SimExpr(other) : 54 24

RAP1(1) AND MCM1'(1) => SimExpr(YGR085C) OR SimExpr(other) : 18 5

RAP1(1) AND SCB(1) => SimExpr(YGR085C) OR SimExpr(other) : 11 3

RAP1(1) AND STRE(1) => SimExpr(YGR085C) : 5

RAP1(1) AND ALPHA1(1) AND SCB(1) => SimExpr(YGR085C) : 6

EXPR: (0.073) SCB (P < 0.000) RAP1 (P < 0.011) ALPHA1 (P < 0.000)

mRRPE(1) AND PAC(1) => SimExpr(YNL110C) OR SimExpr(other) : 78 7

MIG1(1) AND PAC(1) => SimExpr(YNL110C) OR SimExpr(other) : 5 2

EXPR: (0.199) PAC (P < 0.723) MIG1 (P < 0.014)

LYS14(1) AND mRRPE(1) AND PAC(1) => SimExpr(YNL110C) : 9

ALPHA2(1) AND ndt80(MSE)(1) => SimExpr(YGR060W) : 5

EXPR: (0.116) ALPHA2 (P < 0.002) ndt80(MSE) (P < 0.000)

ORF SYMBOL P F C TF
YBR115C LYS2 lysine biosynthesis\, aminoadipic pathway ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis aminoadipate-semialdehyde dehydrogenase activity ->
aminoadipate-semialdehyde dehydrogenase activity cytoplasm ->
cytoplasm DAL81, GCN4
YPR122W AXL1 axial budding, bud site selection, conjugation with cellular fusion, peptide pheromone maturation ->
asexual reproduction, conjugation, protein metabolism, cell proliferation, cell organization and biogenesis, sexual reproduction metalloendopeptidase activity ->
metalloendopeptidase activity integral to membrane, bud neck, shmoo tip ->
integral to membrane, site of polarized growth (sensu Fungi) CIN5
YGR060W ERG25 ergosterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism C-4 methyl sterol oxidase activity ->
C-4 methyl sterol oxidase activity endoplasmic reticulum membrane, plasma membrane ->
cytoplasm, plasma membrane, endomembrane system HSF1, MAL13, MET4, NDD1, SWI5
YOL028C YAP7 positive regulation of transcription from Pol II promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription RNA polymerase II transcription factor activity ->
RNA polymerase II transcription factor activity nucleus ->
nucleus NRG1
YFR032C NO SYMBOL PUT3, SUM1
Main: biosynthesis (0.50) aminoadipate-semialdehyde dehydrogenase activity (0.25) cytoplasm (0.50) SUM1 (0.20)
Score: 0.17 0.00 0.17 0.000
P-value: 1.418E+00 (biosynthesis) 2.181E-01 (oxidoreductase activity) 2.047E+00 (membrane) 3.971E-01 (PUT3)

ALPHA1(1) AND ALPHA2(1) AND LYS14(1) AND ALPHA1'(1) AND SFF'(1) => SimExpr(YGR060W) : 5

EXPR: (0.100) ALPHA2 (P < 0.000) LYS14 (P < 0.002) ALPHA1' (P < 0.001) SFF' (P < 0.000) ALPHA1 (P < 0.000)

ORF SYMBOL P F C TF
YPL140C MKK2 protein amino acid phosphorylation, signal transduction ->
phosphorus metabolism, signal transduction, protein metabolism MAP kinase kinase activity ->
MAP kinase kinase activity intracellular ->
intracellular FKH1, FKH2
YKL054C DEF1 response to DNA damage, ubiquitin-dependent protein catabolism ->
response to biotic stimulus, catabolism, protein metabolism nucleus ->
intracellular
YBR115C LYS2 lysine biosynthesis\, aminoadipic pathway ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis aminoadipate-semialdehyde dehydrogenase activity ->
aminoadipate-semialdehyde dehydrogenase activity cytoplasm ->
intracellular DAL81, GCN4
YKL209C STE6 peptide pheromone export ->
transport ATP-binding cassette (ABC) transporter activity ->
ATP-binding cassette (ABC) transporter activity integral to plasma membrane, shmoo tip ->
integral to membrane, site of polarized growth (sensu Fungi), plasma membrane MCM1, STE12
YGR060W ERG25 ergosterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism C-4 methyl sterol oxidase activity ->
C-4 methyl sterol oxidase activity endoplasmic reticulum membrane, plasma membrane ->
intracellular, plasma membrane, endomembrane system HSF1, MAL13, MET4, NDD1, SWI5
Main: biosynthesis (0.40) aminoadipate-semialdehyde dehydrogenase activity (0.25) intracellular (0.80) FKH2 (0.25)
Score: 0.20 0.00 0.70 0.000
P-value: 1.985E+00 (biosynthesis) 2.181E-01 (oxidoreductase activity) 3.563E-01 (plasma membrane) 5.638E-01 (MAL13)

RAP1(1) AND zap1(1) => SimExpr(YBR118W) : 5

EXPR: (0.131) zap1 (P < 0.000) RAP1 (P < 0.013)

ORF SYMBOL P F C TF
YLR452C SST2 signal transduction, adaptation to pheromone during conjugation with cellular fusion ->
signal transduction, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus GTPase activator activity ->
GTPase activator activity plasma membrane ->
plasma membrane DIG1, FHL1, RAP1, STE12
YGR254W ENO1 gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism phosphopyruvate hydratase activity ->
phosphopyruvate hydratase activity phosphopyruvate hydratase complex, cytoplasm ->
cytoplasm FKH2, MSN4, PDR1, SWI5, YAP5
YKL152C GPM1 gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism phosphoglycerate mutase activity ->
phosphoglycerate mutase activity cytosol ->
cytoplasm GCR1, GCR2, HSF1, RAP1
YPR080W TEF1 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
translation elongation factor activity ribosome ->
cytoplasm, ribonucleoprotein complex FHL1, PDR1, RAP1, YAP5
YBR118W TEF2 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
translation elongation factor activity ribosome ->
cytoplasm, ribonucleoprotein complex FHL1, RAP1
Main: biosynthesis (0.80) translation elongation factor activity (0.40) cytoplasm (0.80) RAP1 (0.80)
Score: 0.60 0.10 0.60 0.700
P-value: 1.036E-02 (translational elongation) 1.700E-03 (translation elongation factor activity) 4.251E-01 (ribosome) 6.212E-04 (RAP1)

RAP1(1) AND mRRPE(1) => SimExpr(YMR014W) OR SimExpr(other) : 10 3

RAP1(1) => SimExpr(YGL076C) OR SimExpr(other) : 53 25

RAP1(1) AND ATRepeat(1) => SimExpr(YGL076C) OR SimExpr(other) : 6 1

RAP1(1) AND SFF'(1) AND ATRepeat(1) => SimExpr(YGL076C) : 5

EXPR: (0.081) SFF' (P < 0.000) ATRepeat (P < 0.000) RAP1 (P < 0.023)

RAP1(1) AND ALPHA1'(1) => SimExpr(YHL033C) OR SimExpr(other) : 30 11

RAP1(1) AND SCB(1) => SimExpr(YHL033C) OR SimExpr(other) : 11 3

RAP1(1) AND ALPHA1'(1) AND SCB(1) => SimExpr(YHL033C) : 7

EXPR: (0.101) ALPHA1' (P < 0.000) SCB (P < 0.000) RAP1 (P < 0.080)

RAP1(1) AND ALPHA1(1) AND SCB(1) => SimExpr(YHL033C) : 6

RAP1(1) => SimExpr(YLR003C) OR SimExpr(other) : 56 22

RAP1(1) AND SFF(1) => SimExpr(YLR003C) OR SimExpr(other) : 35 13

RAP1(1) AND mRRPE(1) => SimExpr(YLR003C) OR SimExpr(other) : 11 2

RAP1(1) AND SFF(1) AND mRRPE(1) => SimExpr(YLR003C) : 5

EXPR: (0.110) SFF (P < 0.000) mRRPE (P < 0.014) RAP1 (P < 0.014)

RAP1(1) AND SFF(1) => SimExpr(YOR369C) OR SimExpr(other) : 34 14

RAP1(1) AND ALPHA1'(1) => SimExpr(YOR369C) OR SimExpr(other) : 28 13

RAP1(1) AND SWI5(1) => SimExpr(YOR369C) OR SimExpr(other) : 19 9

RAP1(1) AND ALPHA2(1) => SimExpr(YOR369C) OR SimExpr(other) : 9 3

RAP1(1) AND ATRepeat(1) => SimExpr(YOR369C) OR SimExpr(other) : 6 1

RAP1(1) AND SCB(1) => SimExpr(YOR369C) OR SimExpr(other) : 10 4

RAP1(1) AND ALPHA1'(1) AND SFF(1) => SimExpr(YOR369C) OR SimExpr(other) : 18 5

RAP1(1) AND ALPHA2(1) AND SFF(1) => SimExpr(YOR369C) : 7

EXPR: (0.110) ALPHA2 (P < 0.000) SFF (P < 0.000) RAP1 (P < 0.032)

RAP1(1) AND SWI5(1) AND SCB(1) => SimExpr(YOR369C) : 5

EXPR: (0.098) SWI5 (P < 0.000) SCB (P < 0.000) RAP1 (P < 0.033)

ORF SYMBOL P F C TF
YBL087C RPL23A protein biosynthesis ->
protein biosynthesis structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome FHL1, IXR1, MSS11, PDR1, RAP1, SMP1, SOK2
YLR344W RPL26A protein biosynthesis ->
protein biosynthesis RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome FHL1, RAP1
YOR369C RPS12 protein biosynthesis ->
protein biosynthesis structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
cytosol, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome ARG80, FHL1, FKH2, LEU3, NDD1, PDR1, RME1, SMP1, YAP6
YPR080W TEF1 translational elongation ->
protein biosynthesis translation elongation factor activity ->
translation elongation factor activity ribosome ->
ribosome FHL1, PDR1, RAP1, YAP5
YLR249W YEF3 translational elongation ->
protein biosynthesis translation elongation factor activity ->
translation elongation factor activity ribosome ->
ribosome INO2, INO4
Main: protein biosynthesis (1.00) structural constituent of ribosome (0.60) ribosome (1.00) FHL1 (0.80)
Score: 1.00 0.40 1.00 0.600
P-value: 1.442E-04 (protein biosynthesis) 1.912E-03 (translation elongation factor activity) 3.195E-05 (ribosome) 5.364E-05 (FHL1)

RAP1(1) AND SFF'(1) AND ATRepeat(1) => SimExpr(YOR369C) : 5

RAP1(1) AND ALPHA2(1) AND SFF'(1) AND SWI5(1) => SimExpr(YOR369C) : 5

EXPR: (0.092) ALPHA2 (P < 0.000) SFF' (P < 0.000) SWI5 (P < 0.000) RAP1 (P < 0.018)

RAP1(1) AND ALPHA1(1) AND ALPHA2(1) AND SFF'(1) => SimExpr(YDL184C) : 6

EXPR: (0.117) ALPHA2 (P < 0.000) SFF' (P < 0.000) RAP1 (P < 0.021) ALPHA1 (P < 0.000)

RAP1(1) AND ALPHA1(1) AND ALPHA2(1) AND SFF(1) => SimExpr(YDL184C) : 5

EXPR: (0.109) ALPHA2 (P < 0.000) SFF (P < 0.000) RAP1 (P < 0.017) ALPHA1 (P < 0.000)

RAP1(1) AND mRRPE(1) => SimExpr(YDL130W) OR SimExpr(other) : 11 2

RAP1(1) AND ALPHA1'(1) => SimExpr(YPL131W) OR SimExpr(other) : 30 11

RAP1(1) AND SCB(1) => SimExpr(YPL131W) OR SimExpr(other) : 11 3

RAP1(1) AND ALPHA1'(1) AND SCB(1) => SimExpr(YPL131W) : 7

RAP1(1) AND ALPHA1(1) AND SCB(1) => SimExpr(YPL131W) : 6

RAP1(1) AND MCM1'(1) => SimExpr(YGL030W) OR SimExpr(other) : 17 6

RAP1(1) AND SWI5(1) => SimExpr(YGL030W) OR SimExpr(other) : 21 7

RAP1(1) AND mRRPE(1) => SimExpr(YGL030W) OR SimExpr(other) : 11 2

RAP1(1) AND SWI5(1) AND MCM1'(1) => SimExpr(YGL030W) : 7

RAP1(1) => SimExpr(YKR092C) OR SimExpr(other) : 53 25

RAP1(1) AND SWI5(1) => SimExpr(YKR092C) OR SimExpr(other) : 20 8

RAP1(1) AND SFF(1) => SimExpr(YOL121C) OR SimExpr(other) : 34 14

RAP1(1) AND mRRPE(1) => SimExpr(YOL121C) OR SimExpr(other) : 11 2

RAP1(1) AND SFF(1) AND mRRPE(1) => SimExpr(YOL121C) : 5

RAP1(1) => SimExpr(YNL288W) OR SimExpr(other) : 55 23

RAP1(1) AND STRE(1) => SimExpr(YNL288W) : 5

RAP1(1) AND SWI5(1) => SimExpr(YKL006W) OR SimExpr(other) : 21 7

RAP1(1) AND MCM1'(1) => SimExpr(YKL006W) OR SimExpr(other) : 17 6

RAP1(1) AND SWI5(1) AND MCM1'(1) => SimExpr(YKL006W) : 7

RAP1(1) AND SFF(1) => SimExpr(YLR441C) OR SimExpr(other) : 34 14

RAP1(1) => SimExpr(YLR452C) OR SimExpr(other) : 53 25

RAP1(1) AND MCM1'(1) => SimExpr(YLR452C) OR SimExpr(other) : 17 6

RAP1(1) AND SWI5(1) => SimExpr(YLR452C) OR SimExpr(other) : 21 7

RAP1(1) AND SWI5(1) AND MCM1'(1) => SimExpr(YLR452C) : 7

RAP1(1) AND ALPHA2(1) => SimExpr(YBR048W) OR SimExpr(other) : 9 3

RAP1(1) AND mRRPE(1) => SimExpr(YBR048W) OR SimExpr(other) : 11 2

RAP1(1) AND ALPHA1'(1) => SimExpr(YJR123W) OR SimExpr(other) : 30 11

RAP1(1) AND SFF(1) => SimExpr(YLR208W) OR SimExpr(other) : 35 13

RAP1(1) AND SCB(1) => SimExpr(YLR208W) OR SimExpr(other) : 11 3

RAP1(1) AND SFF(1) AND SCB(1) => SimExpr(YLR208W) : 10

EXPR: (0.106) SFF (P < 0.000) SCB (P < 0.000) RAP1 (P < 0.004)

ALPHA2(1) AND PAC(1) => SimExpr(YLR249W) OR SimExpr(other) : 18 2

ALPHA1(1) AND mRRPE(1) AND PAC(1) => SimExpr(YLR249W) OR SimExpr(other) : 21 3

mRRPE(1) AND SWI5(1) AND PAC(1) => SimExpr(YLR249W) OR SimExpr(other) : 14 3

RAP1(1) AND SCB(1) => SimExpr(YLR249W) OR SimExpr(other) : 11 3

RAP1(1) AND mRRPE(1) => SimExpr(YLR249W) OR SimExpr(other) : 11 2

RAP1(1) AND ALPHA2(1) => SimExpr(YLR249W) OR SimExpr(other) : 9 3

RAP1(1) AND SWI5(1) => SimExpr(YLR249W) OR SimExpr(other) : 21 7

ALPHA1(1) AND SWI5(1) AND PAC(1) AND SCB(1) => SimExpr(YLR249W) OR SimExpr(other) : 5 1

EXPR: (0.137) SWI5 (P < 0.003) PAC (P < 0.105) SCB (P < 0.009) ALPHA1 (P < 0.000)

ORF SYMBOL P F C TF
|YLR049C| NO SYMBOL MBP1, SWI5
YJL109C UTP10 processing of 20S pre-rRNA ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
YOR294W RRS1 ribosome biogenesis, rRNA processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent nucleus ->
nucleus STB1
YMR259C NO SYMBOL ARG80, GCR2, GTS1, HIR1, SRD1
YDR312W SSF2 ribosomal large subunit assembly and maintenance, conjugation with cellular fusion ->
ribosome biogenesis and assembly, conjugation with cellular fusion rRNA binding ->
RNA binding nucleolus ->
nucleus ABF1, FKH2, INO4, RAP1
YLR249W YEF3 translational elongation ->
protein biosynthesis translation elongation factor activity ->
translation factor activity\, nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex INO2, INO4
Main: ribosome biogenesis and assembly (0.75) RNA binding (0.67) nucleus (0.75) INO4 (0.40)
Score: 0.50 0.33 0.67 0.100
P-value: 2.893E-02 (ribosome biogenesis and assembly) 2.989E-01 (nucleic acid binding) 1.464E-01 (nucleolus) 1.496E-01 (INO4)

RAP1(1) AND STRE(1) => SimExpr(YLR249W) : 5

RAP1(1) AND SFF(1) AND mRRPE(1) => SimExpr(YLR249W) : 5

ALPHA2(1) AND PAC(1) AND SCB(1) => SimExpr(YLR249W) : 8

EXPR: (0.116) ALPHA2 (P < 0.001) PAC (P < 0.029) SCB (P < 0.002)

RAP1(1) AND ALPHA2(1) AND SWI5(1) => SimExpr(YLR249W) : 7

EXPR: (0.100) ALPHA2 (P < 0.000) SWI5 (P < 0.000) RAP1 (P < 0.055)

ORF SYMBOL P F C TF
YBL087C RPL23A protein biosynthesis ->
protein biosynthesis structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome FHL1, IXR1, MSS11, PDR1, RAP1, SMP1, SOK2
YOR369C RPS12 protein biosynthesis ->
protein biosynthesis structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
cytosol, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome ARG80, FHL1, FKH2, LEU3, NDD1, PDR1, RME1, SMP1, YAP6
YBR181C RPS6B protein biosynthesis ->
protein biosynthesis structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya), cytoplasm ->
cytosol, cytoplasm, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome FHL1, GAT3, MAL13, RAP1, RGM1
YDR406W PDR15 transport ->
transport ATP-binding cassette (ABC) transporter activity ->
ATP-binding cassette (ABC) transporter activity integral to membrane ->
integral to membrane
YNL311C NO SYMBOL GCN4, RAP1
YDL184C RPL41A protein biosynthesis ->
protein biosynthesis structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome FHL1, HAL9, HMS1, MAC1, MSS11, RAP1, RME1, SIG1
YLR249W YEF3 translational elongation ->
protein biosynthesis translation elongation factor activity ->
translation elongation factor activity ribosome ->
ribosome INO2, INO4
Main: protein biosynthesis (0.83) structural constituent of ribosome (0.67) ribosome (0.83) RAP1 FHL1 (0.67)
Score: 0.67 0.40 0.67 0.600
P-value: 2.228E-03 (protein biosynthesis) 1.850E-03 (structural constituent of ribosome) 8.021E-04 (ribosome) 5.160E-04 (FHL1)

RAP1(1) AND SWI5(1) AND SCB(1) => SimExpr(YLR249W) : 5

RAP1(1) AND ALPHA1(1) AND SCB(1) => SimExpr(YLR249W) : 6

RAP1(1) AND ALPHA1'(1) => SimExpr(YNL096C) OR SimExpr(other) : 29 12

RAP1(1) => SimExpr(YLR146C) OR SimExpr(other) : 54 24

RAP1(1) AND SFF(1) => SimExpr(YLR146C) OR SimExpr(other) : 36 12

RAP1(1) AND MCM1'(1) => SimExpr(YLR146C) OR SimExpr(other) : 17 6

RAP1(1) AND ATRepeat(1) => SimExpr(YLR146C) OR SimExpr(other) : 6 1

RAP1(1) AND mRRPE(1) => SimExpr(YLR146C) OR SimExpr(other) : 11 2

RAP1(1) AND SFF(1) AND mRRPE(1) => SimExpr(YLR146C) : 5

RAP1(1) AND SFF'(1) AND ATRepeat(1) => SimExpr(YLR146C) : 5

RAP1(1) AND SFF(1) => SimExpr(YDR406W) OR SimExpr(other) : 34 14

RAP1(1) AND SWI5(1) => SimExpr(YBL087C) OR SimExpr(other) : 20 8

RAP1(1) AND SCB(1) => SimExpr(YBL087C) OR SimExpr(other) : 11 3

RAP1(1) AND SFF'(1) AND SWI5(1) => SimExpr(YBL087C) OR SimExpr(other) : 14 6

EXPR: (0.179) SFF' (P < 0.000) SWI5 (P < 0.000) RAP1 (P < 0.497)

RAP1(1) AND SFF(1) AND SWI5(1) => SimExpr(YBL087C) OR SimExpr(other) : 14 4

EXPR: (0.151) SFF (P < 0.000) SWI5 (P < 0.000) RAP1 (P < 0.165)

RAP1(1) AND SWI5(1) AND SCB(1) => SimExpr(YBL087C) : 5

RAP1(1) AND ALPHA1(1) AND SCB(1) => SimExpr(YBL087C) : 6

RAP1(1) AND ALPHA2(1) AND SFF'(1) AND SWI5(1) => SimExpr(YBL087C) : 5

RAP1(1) AND ALPHA2(1) AND SFF(1) AND SWI5(1) => SimExpr(YBL087C) : 5

EXPR: (0.083) ALPHA2 (P < 0.000) SFF (P < 0.000) SWI5 (P < 0.000) RAP1 (P < 0.015)

RAP1(1) AND mRRPE(1) => SimExpr(YPR080W) OR SimExpr(other) : 9 4

RAP1(1) AND ALPHA1(1) AND SCB(1) => SimExpr(YPR080W) : 6

RAP1(1) AND SFF(1) => SimExpr(YDR449C) OR SimExpr(other) : 34 14

RAP1(1) AND ALPHA1'(1) => SimExpr(YDR449C) OR SimExpr(other) : 29 12

RAP1(1) AND mRRPE(1) => SimExpr(YDR449C) OR SimExpr(other) : 10 3

RAP1(1) AND ALPHA1'(1) AND SFF(1) => SimExpr(YDR449C) OR SimExpr(other) : 19 4

RAP1(1) AND SFF(1) AND mRRPE(1) => SimExpr(YDR449C) : 5

RPN4(1) AND MCM1'(1) AND SCB(1) => SimExpr(YGL096W) : 5

ALPHA1'(1) AND STE12(1) AND PAC(1) => SimExpr(YGR251W) OR SimExpr(other) : 5 1

EXPR: (0.172) ALPHA1' (P < 0.004) STE12 (P < 0.010) PAC (P < 0.332)

ORF SYMBOL P F C TF
YNL308C KRI1 ribosome biogenesis ->
cell organization and biogenesis nucleolus ->
nucleus
YGR251W NO SYMBOL MSN4, PHD1, SKN7
YAL059W ECM1 cell wall organization and biogenesis ->
cell organization and biogenesis MOT3
YPR137W RRP9 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex ABF1, HIR1, RCS1
YGR158C MTR3 35S primary transcript processing, mRNA catabolism ->
cell organization and biogenesis, catabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism 3'-5' exoribonuclease activity ->
hydrolase activity\, acting on ester bonds, RNA binding nuclear exosome (RNase complex), cytoplasmic exosome (RNase complex) ->
exosome (RNase complex), cytoplasm, nucleus ZMS1
|YMR302C| PRP12 mitochondrial genome maintenance, rRNA processing ->
cell organization and biogenesis, RNA metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism exonuclease activity ->
hydrolase activity\, acting on ester bonds mitochondrial inner membrane ->
cytoplasm, inner membrane
Main: cell organization and biogenesis (1.00) RNA binding (0.67) nucleus (0.75) ABF1 (0.25)
Score: 1.00 0.67 0.67 0.000
P-value: 5.262E-04 (ribosome biogenesis) 1.709E-02 (exonuclease activity) 1.464E-01 (nucleolus) 2.968E-01 (ZMS1)

mRRPE(1) AND PHO(1) => SimExpr(YGR233C) OR SimExpr(other) : 8 3

EXPR: (0.197) mRRPE (P < 0.154) PHO (P < 0.002)

ORF SYMBOL P F C TF
YBR143C SUP45 translational termination ->
biosynthesis, protein metabolism translation release factor activity\, codon specific ->
translation release factor activity\, codon specific cytosol ->
cytoplasm FZF1
YLR333C RPS25B protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex FHL1, RAP1
|YPR183W| DPM1 N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
lipid biosynthesis, biosynthesis, membrane lipid metabolism, protein metabolism, lipoprotein metabolism transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
cytoplasm, endomembrane system SWI5
YHR007C ERG11 ergosterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism sterol 14-demethylase activity ->
sterol 14-demethylase activity endoplasmic reticulum ->
cytoplasm
YGR233C PHO81 phosphate metabolism ->
phosphorus metabolism cyclin-dependent protein kinase inhibitor activity ->
cyclin-dependent protein kinase inhibitor activity CAD1, CIN5, HIR2, INO4, PHD1
YDR217C RAD9 DNA repair, regulation of cell cycle, nucleotide-excision repair, DNA damage checkpoint, positive regulation of transcription from Pol II promoter ->
cell proliferation, cell cycle, response to biotic stimulus, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism protein binding ->
protein binding nucleus ->
nucleus
YPL032C SVL3 endocytosis ->
transport FKH1, HSF1
|YJR122W| CAF17 YAP1
YBR031W RPL4A protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
YDL167C NRP1
|YGL162W| SUT1 regulation of transcription from Pol II promoter, sterol transport ->
transport, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism specific RNA polymerase II transcription factor activity ->
specific RNA polymerase II transcription factor activity nucleus ->
nucleus
Main: biosynthesis (0.56) structural constituent of ribosome (0.25) cytoplasm (0.71) FZF1 (0.17)
Score: 0.33 0.04 0.52 0.000
P-value: 5.164E-01 (protein biosynthesis) 8.253E-01 (structural constituent of ribosome) 9.328E-01 (cytosolic ribosome (sensu Eukarya)) 1.000E+00

LYS14(1) AND PAC(1) => SimExpr(YMR290C) OR SimExpr(other) : 13 6

LYS14(1) AND mRRPE(1) AND PAC(1) => SimExpr(YMR290C) : 9

ALPHA1(1) AND ABF1(1) AND mRRPE(1) => SimExpr(YDR091C) OR SimExpr(other) : 10 4

EXPR: (0.185) ABF1 (P < 0.003) mRRPE (P < 0.072) ALPHA1 (P < 0.000)

ORF SYMBOL P F C TF
YNL189W SRP1 nucleocytoplasmic transport ->
transport protein carrier activity ->
protein carrier activity nucleus, cytoplasm ->
nucleus, cytoplasm ABF1, MOT3
|YHR061C| GIC1 axial budding, Rho protein signal transduction, establishment of cell polarity (sensu Saccharomyces) ->
asexual reproduction, signal transduction, cell organization and biogenesis small GTPase regulatory/interacting protein activity ->
small GTPase regulatory/interacting protein activity actin cap (sensu Saccharomyces), bud neck, bud tip, incipient bud site ->
cell cortex, site of polarized growth (sensu Fungi), incipient bud site, cytoplasm FKH2, MBP1, STB1, SWI4, SWI6
|YDR374C| NO SYMBOL RME1
YGL253W HXK2 fructose metabolism ->
alcohol metabolism, carbohydrate metabolism hexokinase activity ->
carbohydrate kinase activity, transferase activity\, transferring phosphorus-containing groups nucleus, cytosol ->
nucleus, cytoplasm ABF1, CIN5, HSF1, SWI4
YDR385W EFT2 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
translation factor activity\, nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex ABF1, FHL1, INO4
YDL116W NUP84 mRNA-nucleus export, rRNA-nucleus export, snRNA-nucleus export, tRNA-nucleus export, NLS-bearing substrate-nucleus import, snRNP protein-nucleus import, mRNA-binding (hnRNP) protein-nucleus import, ribosomal protein-nucleus import, protein-nucleus export, nuclear membrane organization and biogenesis, nuclear pore organization and biogenesis ->
intracellular transport, intracellular protein transport, cell organization and biogenesis, protein metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transport structural molecule activity ->
structural molecule activity nuclear pore ->
nucleus, integral to membrane, endomembrane system ABF1
YNL111C CYB5 sterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism electron transporter activity ->
electron transporter activity microsome ->
membrane fraction ABF1, GCR2, GTS1, NRG1, REB1, ROX1
|YJL159W| HSP150 cell wall organization and biogenesis ->
cell organization and biogenesis structural constituent of cell wall ->
structural molecule activity cell wall ->
cell wall ACE2, HIR2, MCM1, RLM1, SWI5
|YIR010W| DSN1 chromosome segregation ->
cell proliferation spindle pole ->
cytoplasm ABF1
YDR091C RLI1 ATP-binding cassette (ABC) transporter activity ->
purine nucleotide binding, primary active transporter activity, hydrolase activity\, acting on acid anhydrides
YDR172W SUP35 translational termination ->
biosynthesis, protein metabolism translation release factor activity ->
translation factor activity\, nucleic acid binding cytosol ->
cytoplasm ABF1, ZMS1
YJL069C UTP18 ABF1
YLR347C KAP95 protein-nucleus import ->
protein metabolism, transport protein carrier activity ->
protein carrier activity cytoplasm, nuclear pore ->
cytoplasm, nucleus, integral to membrane, endomembrane system ABF1, INO4
YBR031W RPL4A protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural molecule activity cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
Main: protein metabolism (0.45) structural molecule activity (0.27) cytoplasm (0.73) ABF1 (0.75)
Score: 0.35 0.09 0.56 0.561
P-value: 8.446E-02 (nucleocytoplasmic transport) 1.710E-02 (protein carrier activity) 3.602E-01 (nuclear pore) 8.105E-07 (ABF1)

ABF1(1) AND SFF(1) AND mRRPE(1) => SimExpr(YDL116W) OR SimExpr(other) : 13 6

EXPR: (0.187) ABF1 (P < 0.009) SFF (P < 0.001) mRRPE (P < 0.131)

ALPHA2(1) AND ndt80(MSE)(1) => SimExpr(YPR122W) : 5

STE12(1) AND PAC(1) => SimExpr(YJL069C) OR SimExpr(other) : 9 2

EXPR: (0.168) STE12 (P < 0.001) PAC (P < 0.388)

ORF SYMBOL P F C TF
|YKL142W| MRP8 protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome mitochondrial ribosome ->
cytoplasm, ribonucleoprotein complex ACE2, CIN5, MBP1, PHO4, REB1, SKN7, STB1
YNL308C KRI1 ribosome biogenesis ->
cell growth and/or maintenance nucleolus ->
nucleus
YGR251W NO SYMBOL MSN4, PHD1, SKN7
YAL059W ECM1 cell wall organization and biogenesis ->
cell growth and/or maintenance MOT3
YBR247C ENP1 processing of 20S pre-rRNA, rRNA processing, cell growth and/or maintenance ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism snoRNA binding ->
RNA binding nucleolus, nucleus ->
nucleus
YMR310C NO SYMBOL
YNL141W AAH1 adenine catabolism ->
aromatic compound metabolism, catabolism, heterocycle metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism adenine deaminase activity ->
hydrolase activity\, acting on carbon-nitrogen (but not peptide) bonds YFL044C
YPR137W RRP9 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex ABF1, HIR1, RCS1
YJL069C UTP18 ABF1
YGR158C MTR3 35S primary transcript processing, mRNA catabolism ->
cell growth and/or maintenance, catabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism 3'-5' exoribonuclease activity ->
hydrolase activity\, acting on ester bonds, RNA binding nuclear exosome (RNase complex), cytoplasmic exosome (RNase complex) ->
exosome (RNase complex), cytoplasm, nucleus ZMS1
|YMR302C| PRP12 mitochondrial genome maintenance, rRNA processing ->
cell growth and/or maintenance, RNA metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism exonuclease activity ->
hydrolase activity\, acting on ester bonds mitochondrial inner membrane ->
cytoplasm, inner membrane
Main: cell growth and/or maintenance (0.75) RNA binding (0.50) nucleus (0.67) ABF1 SKN7 (0.29)
Score: 0.68 0.27 0.67 0.095
P-value: 5.834E-04 (ribosome biogenesis) 1.622E-02 (snoRNA binding) 7.016E-02 (nucleolus) 7.800E-01 (SKN7)

SFF(1) AND mRRPE(1) AND PAC(1) => SimExpr(YJL069C) OR SimExpr(other) : 34 3

EXPR: (0.128) SFF (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.001)

SFF'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YJL069C) OR SimExpr(other) : 40 4

EXPR: (0.133) SFF' (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.003)

ALPHA1(1) AND mRRPE(1) AND PAC(1) => SimExpr(YJL069C) OR SimExpr(other) : 23 1

ABF1(1) AND PAC(1) => SimExpr(YJL069C) : 16

mRRPE(1) AND STE12(1) AND PAC(1) => SimExpr(YJL069C) : 5

SFF(1) AND mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YJL069C) : 11

EXPR: (0.107) SFF (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.011) SCB (P < 0.000)

ORF SYMBOL P F C TF
YHR052W CIC1 protein catabolism ->
macromolecule catabolism, protein metabolism protein binding\, bridging ->
protein binding\, bridging nucleolus, proteasome complex (sensu Eukarya) ->
nucleus, cytoplasm HAP4, MATa1
YJL109C UTP10 processing of 20S pre-rRNA ->
cytoplasm organization and biogenesis, RNA metabolism, transcription snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
YJL138C TIF2 translational initiation, regulation of translational initiation ->
macromolecule biosynthesis, protein metabolism translation initiation factor activity, RNA helicase activity ->
translation factor activity\, nucleic acid binding, RNA binding ribosome, cytoplasm ->
cytoplasm, ribonucleoprotein complex PHD1
YMR259C NO SYMBOL ARG80, GCR2, GTS1, HIR1, SRD1
YNL292W PUS4 tRNA modification ->
RNA metabolism pseudouridylate synthase activity ->
carbon-oxygen lyase activity mitochondrion, nucleus ->
cytoplasm, nucleus RCS1
YCL059C KRR1 ribosome biogenesis, rRNA processing ->
cytoplasm organization and biogenesis, RNA metabolism, transcription nucleolus ->
nucleus
YBR104W YMC2 transport ->
transport transporter activity ->
transporter activity mitochondrial inner membrane ->
cytoplasm, inner membrane FKH1, FKH2
YOR078W BUD21 processing of 20S pre-rRNA ->
cytoplasm organization and biogenesis, RNA metabolism, transcription snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex ABF1, MSS11, SIG1, SKO1
YJL069C UTP18 ABF1
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
cytoplasm organization and biogenesis, RNA metabolism, transcription RNA binding ->
RNA binding nucleolus ->
nucleus
YLR249W YEF3 translational elongation ->
macromolecule biosynthesis, protein metabolism translation elongation factor activity ->
translation factor activity\, nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex INO2, INO4
Main: RNA metabolism (0.56) RNA binding (0.50) nucleus (0.67) ABF1 (0.25)
Score: 0.36 0.25 0.78 0.036
P-value: 4.109E-03 (rRNA processing) 1.327E-02 (snoRNA binding) 3.536E-04 (nucleolus) 1.000E+00

SFF'(1) AND mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YJL069C) : 13

ALPHA1(1) AND mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YJL069C) : 8

EXPR: (0.105) mRRPE (P < 0.000) PAC (P < 0.029) SCB (P < 0.000) ALPHA1 (P < 0.000)

ORF SYMBOL P F C TF
YJL109C UTP10 processing of 20S pre-rRNA ->
ribosome biogenesis, RNA processing, transcription from Pol I promoter snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
YMR131C RRB1 ribosome biogenesis ->
ribosome biogenesis nucleolus ->
nucleus FZF1, MATa1, RGT1
YJR070C NO SYMBOL GAT3, YAP5
YMR239C RNT1 35S primary transcript processing ->
ribosome biogenesis, RNA processing, transcription from Pol I promoter ribonuclease III activity ->
hydrolase activity\, acting on ester bonds, RNA binding nucleolus ->
nucleus
YMR259C NO SYMBOL ARG80, GCR2, GTS1, HIR1, SRD1
YKL056C NO SYMBOL
YJL069C UTP18 ABF1
YLR249W YEF3 translational elongation ->
translational elongation translation elongation factor activity ->
translation factor activity\, nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex INO2, INO4
Main: ribosome biogenesis (0.75) RNA binding (0.67) nucleus (0.75) ABF1 (0.20)
Score: 0.50 0.33 0.67 0.000
P-value: 4.601E-02 (ribosome biogenesis) 5.529E-01 (RNA binding) 2.018E-02 (nucleolus) 1.000E+00

ALPHA1(1) AND SFF(1) AND PAC(1) => SimExpr(YNL163C) OR SimExpr(other) : 22 6

EXPR: (0.166) SFF (P < 0.000) PAC (P < 0.369) ALPHA1 (P < 0.000)

ORF SYMBOL P F C TF
|YMR094W| CTF13 centromere/kinetochore complex maturation ->
cell proliferation centromeric DNA binding, DNA bending activity ->
nucleic acid binding condensed nuclear chromosome kinetochore ->
intracellular
|YLR049C| NO SYMBOL MBP1, SWI5
YDR364C CDC40 DNA replication, S phase of mitotic cell cycle, mRNA splicing, mitotic spindle assembly (sensu Saccharomyces) ->
cytoplasm organization and biogenesis, cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, M phase nucleic acid binding, pre-mRNA splicing factor activity ->
nucleic acid binding spliceosome complex, nuclear membrane, nuclear pore ->
pore complex, intracellular, endomembrane system
YIL118W RHO3 exocytosis, small GTPase mediated signal transduction, establishment of cell polarity (sensu Saccharomyces), actin filament organization ->
signal transduction, cell organization and biogenesis, transport Rho small monomeric GTPase activity, signal transducer activity ->
purine nucleotide binding, signal transducer activity, hydrolase activity\, acting on acid anhydrides intracellular ->
intracellular CIN5, NRG1, PHD1, SKN7, SOK2, YAP6
YJL109C UTP10 processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism snoRNA binding ->
nucleic acid binding small nucleolar ribonucleoprotein complex ->
intracellular
YJL033W HCA4 35S primary transcript processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ATP dependent RNA helicase activity ->
nucleic acid binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
intracellular HIR2, USV1
|YOL075C| NO SYMBOL CRZ1, DAL82, SIP4
|YBL066C| SEF1
YML005W NO SYMBOL USV1
YKR092C SRP40 nucleocytoplasmic transport ->
transport chaperone activity ->
chaperone activity nucleolus ->
intracellular CUP9, MET4, RAP1
YHR169W DBP8 35S primary transcript processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ATP dependent RNA helicase activity ->
nucleic acid binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
intracellular
YNL299W TRF5 sister chromatid cohesion ->
cell proliferation DNA-directed DNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups nucleus ->
intracellular
YMR259C NO SYMBOL ARG80, GCR2, GTS1, HIR1, SRD1
|YJL105W| SET4 ASH1, CIN5, FKH1, MTH1, PHD1, SKN7
YGR251W NO SYMBOL MSN4, PHD1, SKN7
|YPR183W| DPM1 N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
lipid biosynthesis, biosynthesis, membrane lipid metabolism, protein metabolism, lipoprotein metabolism transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
intracellular, endomembrane system SWI5
YNL163C RIA1 ribosome biogenesis ->
cell organization and biogenesis translation elongation factor activity ->
nucleic acid binding cytoplasm ->
intracellular FHL1, RAP1, YAP5
YCR072C NO SYMBOL YFL044C
YML108W NO SYMBOL
YKL078W DHR2 ribosome biogenesis ->
cell organization and biogenesis RNA helicase activity ->
nucleic acid binding nucleolus ->
intracellular ABF1
YGL029W CGR1 ribosome biogenesis, rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism nucleolus ->
intracellular
YPR137W RRP9 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription snoRNA binding ->
nucleic acid binding small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex ->
intracellular ABF1, HIR1, RCS1
YOR381W FRE3 iron-siderochrome transport, iron ion homeostasis ->
transport, cell homeostasis ferric-chelate reductase activity ->
oxidoreductase activity\, oxidizing metal ions plasma membrane, integral to membrane ->
plasma membrane, integral to membrane CIN5, PDR1, YAP6
YOL022C NO SYMBOL MAC1, MOT3, RTS2
YMR290C HAS1 nucleolus, nuclear membrane ->
intracellular, endomembrane system RAP1
YJL069C UTP18 ABF1
YDR312W SSF2 ribosomal large subunit assembly and maintenance, conjugation with cellular fusion ->
cell organization and biogenesis, conjugation, sexual reproduction rRNA binding ->
nucleic acid binding nucleolus ->
intracellular ABF1, FKH2, INO4, RAP1
YLR249W YEF3 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
nucleic acid binding ribosome ->
intracellular INO2, INO4
Main: cell organization and biogenesis (0.56) nucleic acid binding (0.67) intracellular (0.94) ABF1 RAP1 (0.20)
Score: 0.40 0.45 0.88 0.111
P-value: 6.177E-04 (ribosome biogenesis and assembly) 4.598E-02 (RNA helicase activity) 6.790E-06 (nucleolus) 1.000E+00

ALPHA2(1) AND PAC(1) => SimExpr(YML108W) OR SimExpr(other) : 15 5

ALPHA2(1) AND SFF'(1) AND PAC(1) => SimExpr(YML108W) OR SimExpr(other) : 9 3

EXPR: (0.173) ALPHA2 (P < 0.001) SFF' (P < 0.000) PAC (P < 0.109)

ORF SYMBOL P F C TF
|YHR027C| RPN1 ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism endopeptidase activity, receptor activity ->
peptidase activity, receptor activity proteasome regulatory particle (sensu Eukarya), endoplasmic reticulum, cytoplasm ->
cytoplasm, nucleus
YDR364C CDC40 DNA replication, S phase of mitotic cell cycle, mRNA splicing, mitotic spindle assembly (sensu Saccharomyces) ->
cytoplasm organization and biogenesis, cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, M phase nucleic acid binding, pre-mRNA splicing factor activity ->
nucleic acid binding spliceosome complex, nuclear membrane, nuclear pore ->
nucleus, pore complex, ribonucleoprotein complex, endomembrane system
YJL033W HCA4 35S primary transcript processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ATP dependent RNA helicase activity ->
nucleic acid binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus HIR2, USV1
|YPR183W| DPM1 N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
lipid biosynthesis, biosynthesis, membrane lipid metabolism, protein metabolism, lipoprotein metabolism transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
cytoplasm, endomembrane system SWI5
YNR046W NO SYMBOL ABF1
YML108W NO SYMBOL
YGL029W CGR1 ribosome biogenesis, rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism nucleolus ->
nucleus
YNL023C FAP1 transcription factor activity ->
nucleic acid binding
YLR222C UTP13 processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism snoRNA binding ->
nucleic acid binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex ABF1
YDR312W SSF2 ribosomal large subunit assembly and maintenance, conjugation with cellular fusion ->
cell organization and biogenesis, conjugation, sexual reproduction rRNA binding ->
nucleic acid binding nucleolus ->
nucleus ABF1, FKH2, INO4, RAP1
|YPL106C| SSE1 protein folding ->
protein metabolism co-chaperone activity ->
co-chaperone activity cytoplasm ->
cytoplasm HSF1, MSN4
YLR249W YEF3 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex INO2, INO4
Main: cell organization and biogenesis (0.44) nucleic acid binding (0.67) nucleus (0.67) ABF1 (0.43)
Score: 0.42 0.42 0.67 0.190
P-value: 3.275E-02 (ribosome biogenesis and assembly) 5.023E-02 (nucleic acid binding) 9.619E-03 (nucleolus) 4.201E-01 (ABF1)

ALPHA1(1) AND ALPHA2(1) AND PAC(1) => SimExpr(YML108W) OR SimExpr(other) : 8 3

EXPR: (0.189) ALPHA2 (P < 0.001) PAC (P < 0.273) ALPHA1 (P < 0.002)

ORF SYMBOL P F C TF
YDR364C CDC40 DNA replication, S phase of mitotic cell cycle, mRNA splicing, mitotic spindle assembly (sensu Saccharomyces) ->
cytoplasm organization and biogenesis, cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, M phase nucleic acid binding, pre-mRNA splicing factor activity ->
nucleic acid binding spliceosome complex, nuclear membrane, nuclear pore ->
nucleus, ribonucleoprotein complex, membrane
YJL033W HCA4 35S primary transcript processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ATP dependent RNA helicase activity ->
nucleic acid binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus HIR2, USV1
|YOR284W| HUA2 RFX1, YAP6
|YJR070C| NO SYMBOL GAT3, YAP5
|YPR183W| DPM1 N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
lipid biosynthesis, biosynthesis, membrane lipid metabolism, protein metabolism, lipoprotein metabolism transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
cytoplasm, membrane SWI5
YML108W NO SYMBOL
YFL007W BLM3 membrane ->
membrane
YGL029W CGR1 ribosome biogenesis, rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism nucleolus ->
nucleus
YHR128W FUR1 pyrimidine salvage ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism uracil phosphoribosyltransferase activity ->
transferase activity\, transferring glycosyl groups CIN5
YDR312W SSF2 ribosomal large subunit assembly and maintenance, conjugation with cellular fusion ->
cell organization and biogenesis, conjugation, sexual reproduction rRNA binding ->
nucleic acid binding nucleolus ->
nucleus ABF1, FKH2, INO4, RAP1
YLR249W YEF3 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex INO2, INO4
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.57) nucleic acid binding (0.67) nucleus (0.57) INO4 (0.29)
Score: 0.52 0.47 0.52 0.048
P-value: 2.492E-01 (ribosome biogenesis and assembly) 2.496E-01 (transferase activity\, transferring glycosyl groups) 7.796E-02 (nucleolus) 4.995E-01 (INO4)

ALPHA2(1) AND SFF(1) AND PAC(1) => SimExpr(YML108W) OR SimExpr(other) : 8 1

EXPR: (0.172) ALPHA2 (P < 0.001) SFF (P < 0.000) PAC (P < 0.141)

ORF SYMBOL P F C TF
YDR364C CDC40 DNA replication, S phase of mitotic cell cycle, mRNA splicing, mitotic spindle assembly (sensu Saccharomyces) ->
DNA replication and chromosome cycle, mitotic cell cycle, organelle organization and biogenesis, M phase, DNA metabolism, RNA processing, nuclear division nucleic acid binding, pre-mRNA splicing factor activity ->
nucleic acid binding spliceosome complex, nuclear membrane, nuclear pore ->
nucleus, pore complex, ribonucleoprotein complex, endomembrane system
YJL033W HCA4 35S primary transcript processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent ATP dependent RNA helicase activity ->
nucleic acid binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus HIR2, USV1
|YPR183W| DPM1 N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
phospholipid biosynthesis, protein biosynthesis, glycerophospholipid metabolism, protein modification, glycoprotein metabolism, lipoprotein metabolism transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
cytoplasm, endomembrane system SWI5
YML108W NO SYMBOL
YGL029W CGR1 ribosome biogenesis, rRNA processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent nucleolus ->
nucleus
YNL023C FAP1 transcription factor activity ->
nucleic acid binding
YLR222C UTP13 processing of 20S pre-rRNA ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent snoRNA binding ->
nucleic acid binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex ABF1
YDR312W SSF2 ribosomal large subunit assembly and maintenance, conjugation with cellular fusion ->
ribosome biogenesis and assembly, conjugation with cellular fusion rRNA binding ->
nucleic acid binding nucleolus ->
nucleus ABF1, FKH2, INO4, RAP1
YLR249W YEF3 translational elongation ->
protein biosynthesis translation elongation factor activity ->
nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex INO2, INO4
Main: RNA processing (0.57) nucleic acid binding (0.86) nucleus (0.71) ABF1 INO4 (0.40)
Score: 0.48 0.71 0.67 0.200
P-value: 9.276E-03 (ribosome biogenesis and assembly) 6.081E-03 (nucleic acid binding) 2.436E-03 (nucleolus) 2.088E-01 (INO4)

ALPHA1(1) AND ALPHA2(1) AND SFF'(1) AND PAC(1) => SimExpr(YML108W) OR SimExpr(other) : 6 1

EXPR: (0.179) ALPHA2 (P < 0.012) SFF' (P < 0.007) PAC (P < 0.240) ALPHA1 (P < 0.005)

ORF SYMBOL P F C TF
YDR364C CDC40 DNA replication, S phase of mitotic cell cycle, mRNA splicing, mitotic spindle assembly (sensu Saccharomyces) ->
DNA replication and chromosome cycle, mitotic cell cycle, organelle organization and biogenesis, M phase, DNA metabolism, RNA processing, nuclear division nucleic acid binding, pre-mRNA splicing factor activity ->
nucleic acid binding spliceosome complex, nuclear membrane, nuclear pore ->
nucleus, pore complex, ribonucleoprotein complex, endomembrane system
YJL033W HCA4 35S primary transcript processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent ATP dependent RNA helicase activity ->
nucleic acid binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus HIR2, USV1
|YPR183W| DPM1 N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
phospholipid biosynthesis, protein biosynthesis, glycerophospholipid metabolism, protein modification, glycoprotein metabolism, lipoprotein metabolism transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
cytoplasm, endomembrane system SWI5
YML108W NO SYMBOL
YGL029W CGR1 ribosome biogenesis, rRNA processing ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent nucleolus ->
nucleus
YDR312W SSF2 ribosomal large subunit assembly and maintenance, conjugation with cellular fusion ->
ribosome biogenesis and assembly, conjugation with cellular fusion rRNA binding ->
nucleic acid binding nucleolus ->
nucleus ABF1, FKH2, INO4, RAP1
YLR249W YEF3 translational elongation ->
protein biosynthesis translation elongation factor activity ->
nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex INO2, INO4
Main: RNA processing (0.50) nucleic acid binding (0.80) nucleus (0.67) INO4 (0.50)
Score: 0.40 0.60 0.60 0.167
P-value: 6.047E-02 (ribosome biogenesis and assembly) 6.394E-02 (RNA binding) 1.854E-02 (nucleolus) 1.265E-01 (INO4)

mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YJL109C) OR SimExpr(other) : 20 2

ALPHA1(1) AND SFF'(1) AND PAC(1) => SimExpr(YJL109C) OR SimExpr(other) : 25 10

EXPR: (0.193) SFF' (P < 0.000) PAC (P < 0.368) ALPHA1 (P < 0.000)

ALPHA1(1) AND PAC(1) AND SCB(1) => SimExpr(YJL109C) OR SimExpr(other) : 18 3

ALPHA1(1) AND mRRPE(1) AND PAC(1) => SimExpr(YJL109C) OR SimExpr(other) : 21 3

mRRPE(1) AND SWI5(1) AND PAC(1) => SimExpr(YJL109C) OR SimExpr(other) : 13 4

ALPHA1(1) AND SWI5(1) AND PAC(1) AND SCB(1) => SimExpr(YJL109C) OR SimExpr(other) : 5 1

mRRPE(1) AND SWI5(1) AND PAC(1) AND SCB(1) => SimExpr(YJL109C) : 6

ALPHA1(1) AND mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YJL109C) : 8

ALPHA1(1) AND ALPHA1'(1) AND mRRPE(1) AND SWI5(1) AND SCB(1) => SimExpr(YDR472W) OR SimExpr(other) : 7 1

EXPR: (0.156) ALPHA1' (P < 0.001) mRRPE (P < 0.013) SWI5 (P < 0.001) SCB (P < 0.001) ALPHA1 (P < 0.001)

ORF SYMBOL P F C TF
YGR195W SKI6 mRNA catabolism, 35S primary transcript processing ->
catabolism, cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism 3'-5' exoribonuclease activity ->
hydrolase activity\, acting on ester bonds, RNA binding nuclear exosome (RNase complex), cytoplasmic exosome (RNase complex) ->
exosome (RNase complex), cytoplasm, nucleus HSF1
YJL109C UTP10 processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
YNL111C CYB5 sterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism electron transporter activity ->
electron transporter activity microsome ->
membrane fraction ABF1, GCR2, GTS1, NRG1, REB1, ROX1
YPR080W TEF1 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
translation factor activity\, nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex FHL1, PDR1, RAP1, YAP5
YDR091C RLI1 ATP-binding cassette (ABC) transporter activity ->
purine nucleotide binding, primary active transporter activity, hydrolase activity\, acting on acid anhydrides
YGR001C NO SYMBOL
YDR472W TRS31 ER to Golgi transport ->
transport, vesicle-mediated transport TRAPP ->
cytoplasm GCR1, IXR1, RFX1
|YLR342W| FKS1 beta-1\,3 glucan biosynthesis, cell wall organization and biogenesis ->
biosynthesis, cell organization and biogenesis, carbohydrate metabolism 1\,3-beta-glucan synthase activity ->
transferase activity\, transferring glycosyl groups actin cap (sensu Saccharomyces), 1\,3-beta-glucan synthase complex ->
cell cortex, plasma membrane, cytoplasm MBP1, RLM1, STB1, SWI4
Main: cell organization and biogenesis (0.50) RNA binding (0.33) cytoplasm (0.67) GCR2 (0.20)
Score: 0.40 0.07 0.53 0.000
P-value: 3.789E-01 (rRNA processing) 8.847E-01 (RNA binding) 1.459E+00 (ribonucleoprotein complex) 1.000E+00

ALPHA1(1) AND ALPHA1'(1) AND SFF'(1) AND mRRPE(1) AND SWI5(1) AND SCB(1) => SimExpr(YDR472W) : 5

EXPR: (0.131) ALPHA1' (P < 0.000) SFF' (P < 0.002) mRRPE (P < 0.012) SWI5 (P < 0.000) SCB (P < 0.001) ALPHA1 (P < 0.003)

ORF SYMBOL P F C TF
YGR195W SKI6 mRNA catabolism, 35S primary transcript processing ->
mRNA catabolism, rRNA processing 3'-5' exoribonuclease activity ->
hydrolase activity\, acting on ester bonds, RNA binding nuclear exosome (RNase complex), cytoplasmic exosome (RNase complex) ->
exosome (RNase complex), cytoplasm, nucleus HSF1
YJL109C UTP10 processing of 20S pre-rRNA ->
rRNA processing snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
YNL111C CYB5 sterol biosynthesis ->
sterol biosynthesis electron transporter activity ->
electron transporter activity microsome ->
membrane fraction ABF1, GCR2, GTS1, NRG1, REB1, ROX1
YDR091C RLI1 ATP-binding cassette (ABC) transporter activity ->
purine nucleotide binding, primary active transporter activity, hydrolase activity\, acting on acid anhydrides
YDR472W TRS31 ER to Golgi transport ->
ER to Golgi transport TRAPP ->
cytoplasm GCR1, IXR1, RFX1
Main: rRNA processing (0.50) RNA binding (0.50) cytoplasm (0.50) GCR2 (0.33)
Score: 0.17 0.17 0.33 0.000
P-value: 1.352E-01 (rRNA processing) 3.647E-01 (RNA binding) 3.365E+00 (nucleus) 5.292E-01 (GCR1)

ALPHA1(1) AND ALPHA1'(1) AND SFF(1) AND mRRPE(1) AND SWI5(1) AND SCB(1) => SimExpr(YDR472W) : 5

EXPR: (0.131) ALPHA1' (P < 0.000) SFF (P < 0.001) mRRPE (P < 0.006) SWI5 (P < 0.001) SCB (P < 0.001) ALPHA1 (P < 0.001)

PAC(1) => SimExpr(YKL078W) OR SimExpr(other) : 131 45

EXPR: (0.171) PAC (P < 0.499)

ALPHA1(1) AND PAC(1) => SimExpr(YKL078W) OR SimExpr(other) : 45 14

ABF1(1) AND PAC(1) => SimExpr(YKL078W) : 16

mRRPE(1) AND ALPHA2'(1) => SimExpr(YBL092W) OR SimExpr(other) : 11 4

EXPR: (0.198) mRRPE (P < 0.049) ALPHA2' (P < 0.000)

ORF SYMBOL P F C TF
|YOL091W| SPO21 spore wall assembly (sensu Saccharomyces), meiosis ->
cell proliferation, sporulation structural molecule activity ->
structural molecule activity spindle pole body ->
cytoplasm HAP5, SUM1
|YNL122C| NO SYMBOL ARO80
|YFR009W| GCN20 regulation of translational elongation ->
biosynthesis, protein metabolism cytosol, cytosolic ribosome (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
YJR025C BNA1 nicotinamide adenine dinucleotide biosynthesis ->
coenzymes and prosthetic group metabolism, biosynthesis, water-soluble vitamin metabolism, vitamin metabolism 3-hydroxyanthranilate 3\,4-dioxygenase activity ->
3-hydroxyanthranilate 3\,4-dioxygenase activity cytoplasm ->
cytoplasm GCN4, SUM1, SWI6
YLR022C NO SYMBOL USV1
YDR399W HPT1 purine nucleotide biosynthesis ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism hypoxanthine phosphoribosyltransferase activity ->
hypoxanthine phosphoribosyltransferase activity
YPR117W NO SYMBOL IME4, MBP1, SFP1
YLR175W CBF5 rRNA modification, 35S primary transcript processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription pseudouridylate synthase activity ->
pseudouridylate synthase activity small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex AZF1, HAL9
YGR094W VAS1 valyl-tRNA aminoacylation ->
biosynthesis, protein metabolism valine-tRNA ligase activity ->
valine-tRNA ligase activity cytoplasm, mitochondrion ->
cytoplasm SIG1
YLR355C ILV5 branched chain family amino acid biosynthesis, mitochondrial genome maintenance ->
amine metabolism, cell organization and biogenesis, amino acid and derivative metabolism, organic acid metabolism, biosynthesis ketol-acid reductoisomerase activity ->
ketol-acid reductoisomerase activity mitochondrion ->
cytoplasm GCN4, MET4
|YOR295W| UAF30 transcription from Pol I promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA polymerase I transcription factor activity, ribosomal DNA (rDNA) binding ->
RNA polymerase I transcription factor activity, ribosomal DNA (rDNA) binding RNA polymerase I upstream activating factor complex ->
nucleus
YBL092W RPL32 protein biosynthesis ->
biosynthesis, protein metabolism structural molecule activity ->
structural molecule activity cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, RAP1
YOR095C RKI1 pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism ribose-5-phosphate isomerase activity ->
ribose-5-phosphate isomerase activity FHL1, FKH2, RAP1
YGR001C NO SYMBOL
YDR119W NO SYMBOL MSS11, SIG1, SKO1
Main: biosynthesis (0.60) structural molecule activity (0.22) cytoplasm (0.75) SUM1 RAP1 FHL1 SIG1 GCN4 (0.18)
Score: 0.44 0.03 0.64 0.073
P-value: 2.312E-01 (pyridine nucleotide metabolism) 1.712E+00 (oxidoreductase activity) 1.398E+00 (nucleolus) 2.613E-01 (SIG1)

ALPHA1(1) AND mRRPE(1) AND ALPHA2'(1) => SimExpr(YBL092W) : 6

mRRPE(1) AND MCM1'(1) AND ALPHA2'(1) => SimExpr(YBL092W) : 6

ALPHA2(1) AND ndt80(MSE)(1) => SimExpr(YBR115C) : 5

mRRPE(1) AND MCM1'(1) AND ALPHA2'(1) => SimExpr(YGR001C) OR SimExpr(other) : 5 1

ALPHA1(1) AND ALPHA2(1) AND ALPHA1'(1) AND SWI5(1) AND SCB(1) => SimExpr(YGR001C) OR SimExpr(other) : 6 1

ALPHA1(1) AND ALPHA2(1) AND SWI5(1) AND MCM1'(1) AND SCB(1) => SimExpr(YGR001C) : 5

EXPR: (0.117) ALPHA2 (P < 0.000) SWI5 (P < 0.000) MCM1' (P < 0.000) SCB (P < 0.001) ALPHA1 (P < 0.000)

ORF SYMBOL P F C TF
YIL035C CKA1 flocculation, protein amino acid phosphorylation, cell ion homeostasis, G1/S transition of mitotic cell cycle, G2/M transition of mitotic cell cycle, establishment of cell polarity (sensu Saccharomyces), regulation of transcription from Pol I promoter, regulation of transcription from Pol III promoter, response to DNA damage ->
flocculation, protein amino acid phosphorylation, cell ion homeostasis, G1/S transition of mitotic cell cycle, G2/M transition of mitotic cell cycle, establishment of cell polarity (sensu Saccharomyces), regulation of transcription from Pol I promoter, regulation of transcription from Pol III promoter, response to DNA damage protein kinase CK2 activity ->
protein kinase CK2 activity protein kinase CK2 complex ->
protein kinase CK2 complex ABF1
YHR046C INM1 myo-inositol metabolism ->
myo-inositol metabolism myo-inositol-1(or 4)-monophosphatase activity ->
myo-inositol-1(or 4)-monophosphatase activity
YPR195C NO SYMBOL FKH1, FKH2, HIR1, HIR2, INO4, RLM1
YKL209C STE6 peptide pheromone export ->
peptide pheromone export ATP-binding cassette (ABC) transporter activity ->
ATP-binding cassette (ABC) transporter activity integral to plasma membrane, shmoo tip ->
integral to plasma membrane, shmoo tip MCM1, STE12
YGR001C NO SYMBOL
Main: myo-inositol metabolism (0.33) protein kinase CK2 activity (0.33) integral to plasma membrane (0.50) ABF1 (0.33)
Score: 0.00 0.00 0.00 0.000
P-value: 5.103E+00 (cell growth and/or maintenance) 9.768E-01 (hydrolase activity) 2.000E+00 6.404E-01 (HIR2)

ALPHA1'(1) AND SWI5(1) AND PAC(1) => SimExpr(YOR294W) OR SimExpr(other) : 14 6

EXPR: (0.181) ALPHA1' (P < 0.001) SWI5 (P < 0.000) PAC (P < 0.739)

ORF SYMBOL P F C TF
|YFL011W| HXT10 hexose transport ->
transport glucose transporter activity, fructose transporter activity, mannose transporter activity, galactose transporter activity ->
hexose transporter activity plasma membrane ->
plasma membrane GTS1, MBP1, RTG3
YJL109C UTP10 processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
|YOL075C| NO SYMBOL CRZ1, DAL82, SIP4
YIL066C RNR3 DNA replication ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ribonucleoside-diphosphate reductase activity ->
oxidoreductase activity\, acting on CH2 groups cytoplasm ->
cytoplasm RFX1, STB1
YNR024W NO SYMBOL
YOR294W RRS1 ribosome biogenesis, rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism nucleus ->
nucleus STB1
YFR001W LOC1 ribosomal large subunit biogenesis ->
cell organization and biogenesis mRNA binding ->
RNA binding nucleus ->
nucleus ARG80, GAL4, GTS1, HAP4, HIR1, LEU3, MSN2, MSN4, RCS1, RLM1, SWI4
|YJL105W| SET4 ASH1, CIN5, FKH1, MTH1, PHD1, SKN7
YGR251W NO SYMBOL MSN4, PHD1, SKN7
|YPR183W| DPM1 N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
lipid biosynthesis, biosynthesis, membrane lipid metabolism, protein metabolism, lipoprotein metabolism transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
cytoplasm, endomembrane system SWI5
YGR245C SDA1 actin cytoskeleton organization and biogenesis, start control point of mitotic cell cycle ->
cell organization and biogenesis, cell proliferation nucleus ->
nucleus
YBR292C NO SYMBOL STE12, ZMS1
YPR010C RPA135 transcription from Pol I promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DNA-directed RNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups DNA-directed RNA polymerase I complex ->
nucleus ROX1, SIG1
YOR310C NOP58 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex ABF1, SWI6
|YLL010C| PSR1 response to stress ->
response to stress protein phosphatase activity ->
hydrolase activity\, acting on ester bonds plasma membrane ->
plasma membrane CBF1
|YDR279W| RNH202 GCR2, MBP1, RIM101, RLM1, SWI6, THI2
YMR229C RRP5 rRNA processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding, snoRNA binding ->
RNA binding nucleolus, nucleolus organizer complex ->
nucleus FHL1, RAP1
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding nucleolus ->
nucleus
YPL143W RPL33A protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, MET4, NDD1, PDR1, RAP1, RME1
YKL120W OAC1 oxaloacetate transport, sulfate transport ->
transport oxaloacetate carrier activity, sulfate porter activity ->
electrochemical potential-driven transporter activity, anion transporter activity, organic cation transporter activity, carboxylic acid transporter activity mitochondrial inner membrane ->
cytoplasm, inner membrane LEU3, MTH1
Main: cell organization and biogenesis (0.50) RNA binding (0.36) nucleus (0.57) RLM1 MTH1 RAP1 SKN7 STB1 PHD1 LEU3 FHL1 MBP1 MSN4 SWI6 GTS1 (0.12)
Score: 0.38 0.11 0.41 0.083
P-value: 1.048E-03 (transcription from Pol I promoter) 4.467E-02 (snoRNA binding) 8.984E-03 (nucleolus) 7.332E-01 (LEU3)

ALPHA1(1) AND LYS14(1) AND mRRPE(1) => SimExpr(YGR240C) OR SimExpr(other) : 9 4

EXPR: (0.205) LYS14 (P < 0.000) mRRPE (P < 0.049) ALPHA1 (P < 0.000)

ORF SYMBOL P F C TF
YMR277W FCP1 protein amino acid dephosphorylation, transcription ->
phosphorus metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism protein phosphatase activity, phosphoric monoester hydrolase activity ->
hydrolase activity\, acting on ester bonds nucleus ->
nucleus
|YNL042W| BOP3 DAL82
YJR070C NO SYMBOL GAT3, YAP5
|YPL128C| TBF1 loss of chromatin silencing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription DNA binding, transcription factor activity ->
DNA binding nuclear chromosome\, telomeric region, nuclear chromosome, nucleus ->
chromosome, nucleus
YMR259C NO SYMBOL ARG80, GCR2, GTS1, HIR1, SRD1
|YMR042W| ARG80 positive regulation of transcription from Pol II promoter, arginine metabolism ->
amine metabolism, nitrogen metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, amino acid and derivative metabolism, organic acid metabolism DNA binding, specific RNA polymerase II transcription factor activity ->
DNA binding, specific RNA polymerase II transcription factor activity nucleus ->
nucleus RME1
YGR240C PFK1 glycolysis ->
carbohydrate metabolism, alcohol metabolism, carbohydrate catabolism, energy pathways, catabolism 6-phosphofructokinase activity ->
carbohydrate kinase activity, transferase activity\, transferring phosphorus-containing groups 6-phosphofructokinase complex, cytoplasm ->
cytoplasm GCR1, HIR1, HIR2
|YLR328W| NMA1 nicotinamide adenine dinucleotide metabolism ->
coenzymes and prosthetic group metabolism, vitamin metabolism nicotinamide-nucleotide adenylyltransferase activity ->
transferase activity\, transferring phosphorus-containing groups CIN5, MSN1, ROX1
YHR128W FUR1 pyrimidine salvage ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism uracil phosphoribosyltransferase activity ->
transferase activity\, transferring glycosyl groups CIN5
YNL102W POL1 DNA replication\, priming, DNA replication initiation, lagging strand elongation, DNA repair synthesis ->
DNA metabolism, cell proliferation alpha DNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups alpha DNA polymerase\:primase complex ->
nucleus LEU3, MBP1
YMR290C HAS1 nucleolus, nuclear membrane ->
nucleus, endomembrane system RAP1
YPL032C SVL3 endocytosis ->
transport FKH1, HSF1
YBL092W RPL32 protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, RAP1
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.44) transferase activity\, transferring phosphorus-containing groups (0.38) nucleus (0.71) RAP1 CIN5 HIR1 (0.18)
Score: 0.22 0.14 0.52 0.055
P-value: 2.612E+00 (regulation of transcription\, DNA-dependent) 1.868E-01 (nucleotidyltransferase activity) 3.063E+00 (cytosol) 4.268E-01 (HIR1)

LYS14(1) AND mRRPE(1) AND SWI5(1) => SimExpr(YGR240C) OR SimExpr(other) : 7 2

EXPR: (0.200) LYS14 (P < 0.000) mRRPE (P < 0.070) SWI5 (P < 0.000)

ORF SYMBOL P F C TF
YPR074C TKL1 pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism transketolase activity ->
transketolase activity cytoplasm ->
cytoplasm REB1
YKL018W SWD2 histone methylation ->
cell organization and biogenesis, protein metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism histone-lysine N-methyltransferase activity ->
histone-lysine N-methyltransferase activity nucleus ->
nucleus
YMR259C NO SYMBOL ARG80, GCR2, GTS1, HIR1, SRD1
YGR240C PFK1 glycolysis ->
carbohydrate metabolism, alcohol metabolism, carbohydrate catabolism, energy pathways, catabolism 6-phosphofructokinase activity ->
6-phosphofructokinase activity 6-phosphofructokinase complex, cytoplasm ->
cytoplasm GCR1, HIR1, HIR2
|YKL109W| HAP4 transcription, regulation of carbohydrate metabolism ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, carbohydrate metabolism, energy pathways, regulation of metabolism transcriptional activator activity ->
transcriptional activator activity CCAAT-binding factor complex ->
nucleus ASH1, PHD1, SKN7, SWI4, YAP6
YOR063W RPL3 protein biosynthesis, ribosomal large subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex GRF10(Pho2)
|YJR129C| NO SYMBOL DOT6, SIP4
YPL032C SVL3 endocytosis ->
transport FKH1, HSF1
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding nucleolus ->
nucleus
Main: cell organization and biogenesis (0.43) 6-phosphofructokinase activity (0.17) cytoplasm (0.50) HIR1 (0.29)
Score: 0.38 0.00 0.40 0.048
P-value: 9.305E-02 (glucose catabolism) 6.615E-01 (transferase activity) 1.871E+00 (cytosol) 1.855E-01 (HIR1)

ALPHA1(1) AND mRRPE(1) AND PAC(1) => SimExpr(YMR239C) OR SimExpr(other) : 23 1

ALPHA1(1) AND mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YMR239C) : 8

ALPHA1(1) AND ALPHA2(1) AND ALPHA1'(1) AND mRRPE(1) => SimExpr(YDR023W) OR SimExpr(other) : 9 3

EXPR: (0.177) ALPHA2 (P < 0.000) ALPHA1' (P < 0.002) mRRPE (P < 0.062) ALPHA1 (P < 0.000)

ORF SYMBOL P F C TF
|YPL193W| RSA1 ribosomal large subunit assembly and maintenance ->
cell organization and biogenesis nucleoplasm ->
nucleus
YJL033W HCA4 35S primary transcript processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus HIR2, USV1
YJR070C NO SYMBOL GAT3, YAP5
|YPR183W| DPM1 N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
lipid biosynthesis, biosynthesis, membrane lipid metabolism, protein metabolism, lipoprotein metabolism transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
cytoplasm, endomembrane system SWI5
YNL111C CYB5 sterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism electron transporter activity ->
electron transporter activity microsome ->
membrane fraction ABF1, GCR2, GTS1, NRG1, REB1, ROX1
YGL029W CGR1 ribosome biogenesis, rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism nucleolus ->
nucleus
YHR128W FUR1 pyrimidine salvage ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism uracil phosphoribosyltransferase activity ->
transferase activity\, transferring glycosyl groups CIN5
YBR048W RPS11B protein biosynthesis, ribosomal small subunit assembly and maintenance, regulation of translational fidelity ->
cell organization and biogenesis, biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex GAL4, HAP4, LEU3, MET31, MSN1
YNR054C NO SYMBOL HAP3, HAP5, IXR1, MCM1, RTG3, SFP1, SWI6
|YBR294W| SUL1 sulfate transport ->
transport sulfate transporter activity ->
anion transporter activity plasma membrane ->
plasma membrane STB1
YDR023W SES1 amino acid activation ->
biosynthesis, protein metabolism serine-tRNA ligase activity ->
ligase activity\, forming carbon-oxygen bonds, ligase activity\, forming phosphoric ester bonds cytoplasm ->
cytoplasm GRF10(Pho2), MOT3
YGR001C NO SYMBOL
Main: biosynthesis (0.56) transferase activity\, transferring glycosyl groups (0.29) cytoplasm (0.38) GCR2 (0.11)
Score: 0.50 0.05 0.21 0.000
P-value: 3.899E-02 (ribosome biogenesis and assembly) 2.210E-01 (transferase activity\, transferring glycosyl groups) 6.317E-01 (nucleolus) 1.000E+00

ALPHA2(1) AND PAC(1) => SimExpr(YHR128W) OR SimExpr(other) : 18 2

ALPHA1(1) AND mRRPE(1) AND PAC(1) => SimExpr(YHR128W) OR SimExpr(other) : 22 2

LYS14(1) AND mRRPE(1) AND PAC(1) => SimExpr(YHR128W) : 9

ALPHA1(1) AND ALPHA2(1) AND ALPHA1'(1) AND PAC(1) => SimExpr(YJL033W) OR SimExpr(other) : 5 1

EXPR: (0.167) ALPHA2 (P < 0.000) ALPHA1' (P < 0.003) PAC (P < 0.265) ALPHA1 (P < 0.002)

ORF SYMBOL P F C TF
YDR364C CDC40 DNA replication, S phase of mitotic cell cycle, mRNA splicing, mitotic spindle assembly (sensu Saccharomyces) ->
cytoplasm organization and biogenesis, cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, M phase nucleic acid binding, pre-mRNA splicing factor activity ->
nucleic acid binding spliceosome complex, nuclear membrane, nuclear pore ->
nucleus, pore complex, ribonucleoprotein complex, endomembrane system
YJL033W HCA4 35S primary transcript processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ATP dependent RNA helicase activity ->
nucleic acid binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus HIR2, USV1
YJR070C NO SYMBOL GAT3, YAP5
|YPR183W| DPM1 N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
lipid biosynthesis, biosynthesis, membrane lipid metabolism, protein metabolism, lipoprotein metabolism transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
cytoplasm, endomembrane system SWI5
YGL029W CGR1 ribosome biogenesis, rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism nucleolus ->
nucleus
YHR128W FUR1 pyrimidine salvage ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism uracil phosphoribosyltransferase activity ->
transferase activity\, transferring glycosyl groups CIN5
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.80) nucleic acid binding (0.50) nucleus (0.75) HIR2 (0.25)
Score: 0.70 0.33 0.67 0.000
P-value: 8.095E-02 (RNA processing) 7.391E-02 (transferase activity\, transferring glycosyl groups) 1.673E-01 (nucleolus) 4.383E-01 (USV1)

ALPHA1(1) AND SWI5(1) AND PAC(1) => SimExpr(YDR312W) OR SimExpr(other) : 13 5

EXPR: (0.188) SWI5 (P < 0.000) PAC (P < 0.689) ALPHA1 (P < 0.000)

ORF SYMBOL P F C TF
|YLR049C| NO SYMBOL MBP1, SWI5
YJL109C UTP10 processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
|YOL075C| NO SYMBOL CRZ1, DAL82, SIP4
YKR092C SRP40 nucleocytoplasmic transport ->
transport chaperone activity ->
chaperone activity nucleolus ->
nucleus CUP9, MET4, RAP1
YOR294W RRS1 ribosome biogenesis, rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism nucleus ->
nucleus STB1
YNL299W TRF5 sister chromatid cohesion ->
cell proliferation DNA-directed DNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups nucleus ->
nucleus
YMR259C NO SYMBOL ARG80, GCR2, GTS1, HIR1, SRD1
YFR001W LOC1 ribosomal large subunit biogenesis ->
cell organization and biogenesis mRNA binding ->
RNA binding nucleus ->
nucleus ARG80, GAL4, GTS1, HAP4, HIR1, LEU3, MSN2, MSN4, RCS1, RLM1, SWI4
|YJL105W| SET4 ASH1, CIN5, FKH1, MTH1, PHD1, SKN7
YGR251W NO SYMBOL MSN4, PHD1, SKN7
YJR002W MPP10 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex, nucleolus, nucleus ->
nucleus, ribonucleoprotein complex
|YPR183W| DPM1 N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
lipid biosynthesis, biosynthesis, membrane lipid metabolism, protein metabolism, lipoprotein metabolism transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
cytoplasm, endomembrane system SWI5
YBR292C NO SYMBOL STE12, ZMS1
YBR069C TAT1 amino acid transport ->
transport amino acid transporter activity ->
carboxylic acid transporter activity plasma membrane ->
plasma membrane CIN5, DAL81, PHD1, SWI4
YMR229C RRP5 rRNA processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding, snoRNA binding ->
RNA binding nucleolus, nucleolus organizer complex ->
nucleus FHL1, RAP1
|YKL145W| RPT1 ubiquitin-dependent protein catabolism ->
catabolism, protein metabolism ATPase activity, endopeptidase activity ->
purine nucleotide binding, peptidase activity, hydrolase activity\, acting on acid anhydrides proteasome regulatory particle (sensu Eukarya) ->
cytoplasm, nucleus REB1
YDR312W SSF2 ribosomal large subunit assembly and maintenance, conjugation with cellular fusion ->
cell organization and biogenesis, conjugation, sexual reproduction rRNA binding ->
RNA binding nucleolus ->
nucleus ABF1, FKH2, INO4, RAP1
YLR249W YEF3 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
translation factor activity\, nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex INO2, INO4
Main: cell organization and biogenesis (0.50) RNA binding (0.40) nucleus (0.75) RAP1 PHD1 (0.20)
Score: 0.29 0.13 0.62 0.105
P-value: 2.185E-03 (ribosome biogenesis and assembly) 3.216E-02 (snoRNA binding) 5.281E-03 (nucleolus) 6.479E-01 (MSN4)

ALPHA2(1) AND PAC(1) => SimExpr(YDR312W) OR SimExpr(other) : 18 2

ALPHA1(1) AND SFF'(1) AND SWI5(1) AND PAC(1) => SimExpr(YDR312W) OR SimExpr(other) : 7 3

EXPR: (0.193) SFF' (P < 0.009) SWI5 (P < 0.004) PAC (P < 0.710) ALPHA1 (P < 0.005)

ORF SYMBOL P F C TF
YJL109C UTP10 processing of 20S pre-rRNA ->
ribosome biogenesis and assembly, RNA processing, transcription\, DNA-dependent snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
|YOL075C| NO SYMBOL CRZ1, DAL82, SIP4
YKR092C SRP40 nucleocytoplasmic transport ->
nucleocytoplasmic transport chaperone activity ->
chaperone activity nucleolus ->
nucleus CUP9, MET4, RAP1
YNL299W TRF5 sister chromatid cohesion ->
DNA replication and chromosome cycle DNA-directed DNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups nucleus ->
nucleus
|YJL105W| SET4 ASH1, CIN5, FKH1, MTH1, PHD1, SKN7
YGR251W NO SYMBOL MSN4, PHD1, SKN7
|YPR183W| DPM1 N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
phospholipid biosynthesis, protein biosynthesis, glycerophospholipid metabolism, protein modification, glycoprotein metabolism, lipoprotein metabolism transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
cytoplasm, endomembrane system SWI5
YBR292C NO SYMBOL STE12, ZMS1
YDR312W SSF2 ribosomal large subunit assembly and maintenance, conjugation with cellular fusion ->
ribosome biogenesis and assembly, conjugation with cellular fusion rRNA binding ->
RNA binding nucleolus ->
nucleus ABF1, FKH2, INO4, RAP1
YLR249W YEF3 translational elongation ->
protein biosynthesis translation elongation factor activity ->
translation factor activity\, nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex INO2, INO4
Main: protein biosynthesis (0.33) RNA binding (0.33) nucleus (0.67) SKN7 RAP1 INO4 PHD1 (0.25)
Score: 0.13 0.07 0.53 0.107
P-value: 9.626E-01 (ribosome biogenesis and assembly) 1.132E+00 (RNA binding) 4.667E-02 (nucleolus) 6.405E-01 (INO4)

ABF1(1) AND PAC(1) => SimExpr(YDR312W) : 16

ALPHA2(1) AND PAC(1) AND SCB(1) => SimExpr(YDR312W) : 8

ALPHA1(1) AND LYS14(1) AND mRRPE(1) => SimExpr(YPL032C) OR SimExpr(other) : 9 4

ALPHA1(1) AND LYS14(1) AND mRRPE(1) => SimExpr(YNL102W) OR SimExpr(other) : 9 4

ALPHA1(1) AND SFF(1) AND PAC(1) => SimExpr(YNL299W) OR SimExpr(other) : 21 7

ALPHA1(1) AND mRRPE(1) AND PAC(1) => SimExpr(YKL056C) OR SimExpr(other) : 18 6

ALPHA1(1) AND mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YKL056C) : 8

ALPHA2(1) AND PAC(1) => SimExpr(YDR364C) OR SimExpr(other) : 18 2

ALPHA2(1) AND PAC(1) AND SCB(1) => SimExpr(YDR364C) : 8

ALPHA1(1) AND ALPHA2(1) AND ALPHA1'(1) AND MCM1'(1) AND SCB(1) => SimExpr(YPR195C) OR SimExpr(other) : 6 2

ALPHA1(1) AND ALPHA2(1) AND SWI5(1) AND SCB(1) => SimExpr(YPR195C) OR SimExpr(other) : 12 2

ALPHA1(1) AND ALPHA2(1) AND ALPHA1'(1) AND SFF(1) AND SCB(1) => SimExpr(YPR195C) OR SimExpr(other) : 7 3

EXPR: (0.196) ALPHA2 (P < 0.006) ALPHA1' (P < 0.007) SFF (P < 0.007) SCB (P < 0.015) ALPHA1 (P < 0.009)

ORF SYMBOL P F C TF
YLR272C YCS4 mitotic chromosome condensation ->
cell proliferation, cell cycle nuclear condensin complex ->
chromosome, nucleus
YDR364C CDC40 DNA replication, S phase of mitotic cell cycle, mRNA splicing, mitotic spindle assembly (sensu Saccharomyces) ->
cytoplasm organization and biogenesis, cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, M phase nucleic acid binding ->
nucleic acid binding spliceosome complex, nuclear membrane, nuclear pore ->
nucleus, pore complex, ribonucleoprotein complex, endomembrane system
|YNL230C| ELA1 RNA elongation from Pol II promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism transcriptional elongation regulator activity ->
transcriptional elongation regulator activity transcription elongation factor complex ->
nucleus PHO4, RCS1, YAP1
YBR115C LYS2 lysine biosynthesis\, aminoadipic pathway ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis aminoadipate-semialdehyde dehydrogenase activity ->
aminoadipate-semialdehyde dehydrogenase activity cytoplasm ->
cytoplasm DAL81, GCN4
YPR195C NO SYMBOL FKH1, FKH2, HIR1, HIR2, INO4, RLM1
YKL209C STE6 peptide pheromone export ->
transport ATP-binding cassette (ABC) transporter activity ->
ATP-binding cassette (ABC) transporter activity integral to plasma membrane, shmoo tip ->
integral to membrane, site of polarized growth (sensu Fungi), plasma membrane MCM1, STE12
YNL111C CYB5 sterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism electron transporter activity ->
electron transporter activity microsome ->
membrane fraction ABF1, GCR2, GTS1, NRG1, REB1, ROX1
|YLR321C| SFH1 chromatin modeling ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism protein binding ->
protein binding nucleosome remodeling complex ->
nucleus
YIL034C CAP2 endocytosis, response to osmotic stress, actin filament organization, cell wall organization and biogenesis ->
transport, response to abiotic stimulus, cell organization and biogenesis protein binding ->
protein binding actin cortical patch (sensu Saccharomyces), actin capping protein complex ->
cell cortex, cytoplasm
|YKL167C| MRP49 protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome mitochondrial large ribosomal subunit ->
cytoplasm, ribonucleoprotein complex ABF1, IME4, IXR1
Main: biosynthesis (0.33) protein binding (0.25) nucleus (0.44) ABF1 (0.33)
Score: 0.25 0.04 0.28 0.067
P-value: 7.408E-01 (mitosis) 8.014E-01 (protein binding) 8.554E-01 (integral to membrane) 1.000E+00

ALPHA1(1) AND ALPHA2(1) AND SWI5(1) AND MCM1'(1) AND SCB(1) => SimExpr(YPR195C) : 5

ABF1(1) AND PAC(1) => SimExpr(YDR527W) OR SimExpr(other) : 13 3

ABF1(1) AND PAC(1) AND SCB(1) => SimExpr(YDR527W) : 6

EXPR: (0.101) ABF1 (P < 0.001) PAC (P < 0.027) SCB (P < 0.000)

ORF SYMBOL P F C TF
YLR197W SIK1 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
RNA processing, ribosome biogenesis and assembly, rRNA metabolism, transcription\, DNA-dependent small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex, nucleus, nucleolus ->
nucleus, ribonucleoprotein complex DAL81, HAL9
YNL292W PUS4 tRNA modification ->
RNA processing, tRNA metabolism pseudouridylate synthase activity ->
carbon-oxygen lyase activity mitochondrion, nucleus ->
cytoplasm, nucleus RCS1
YNL112W DBP2 RNA helicase activity ->
RNA binding bud neck ->
site of polarized growth (sensu Fungi)
YDR527W NO SYMBOL ABF1, SKN7
YJL069C UTP18 ABF1
YDR312W SSF2 ribosomal large subunit assembly and maintenance, conjugation with cellular fusion ->
ribosome biogenesis and assembly, conjugation with cellular fusion rRNA binding ->
RNA binding nucleolus ->
nucleus ABF1, FKH2, INO4, RAP1
Main: RNA processing (0.67) RNA binding (0.67) nucleus (0.75) ABF1 (0.60)
Score: 0.67 0.33 0.50 0.300
P-value: 1.780E-02 (RNA modification) 3.910E-01 (RNA binding) 1.255E-01 (nucleolus) 4.126E-02 (ABF1)

SWI5(1) AND Gcr1(1) AND SCB(1) => SimExpr(YLR272C) OR SimExpr(other) : 6 2

EXPR: (0.191) SWI5 (P < 0.007) Gcr1 (P < 0.008) SCB (P < 0.031)

ORF SYMBOL P F C TF
YLR272C YCS4 mitotic chromosome condensation ->
DNA replication and chromosome cycle, M phase, mitotic cell cycle nuclear condensin complex ->
chromosome, nucleus
|YKL108W| SLD2 DNA strand elongation ->
DNA replication and chromosome cycle, mitotic cell cycle, DNA metabolism replication fork ->
nucleus PHD1
YHR046C INM1 myo-inositol metabolism ->
hexose metabolism myo-inositol-1(or 4)-monophosphatase activity ->
myo-inositol-1(or 4)-monophosphatase activity
YLR354C TAL1 pentose-phosphate shunt ->
monosaccharide catabolism, main pathways of carbohydrate metabolism, oxidoreduction coenzyme metabolism, hexose metabolism, water-soluble vitamin metabolism transaldolase activity ->
transaldolase activity cytoplasm ->
cytoplasm MBP1
YBR088C POL30 leading strand elongation, lagging strand elongation, mutagenesis, base-excision repair, nucleotide-excision repair, mismatch repair, postreplication repair ->
mutagenesis, DNA replication and chromosome cycle, DNA repair, S phase of mitotic cell cycle, DNA metabolism DNA polymerase processivity factor activity ->
DNA polymerase processivity factor activity replication fork ->
nucleus
|YJL052W| TDH1 gluconeogenesis, glycolysis ->
monosaccharide biosynthesis, monosaccharide catabolism, main pathways of carbohydrate metabolism, hexose metabolism glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) activity ->
glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) activity cytosol, lipid particle, cell wall ->
cytoplasm, cell wall MAC1
YPR007C SPO69 meiosis, sister chromatid cohesion ->
M phase, DNA replication and chromosome cycle binding ->
binding condensed nuclear chromosome\, pericentric region, nuclear cohesin complex ->
chromosome, nuclear chromosome MCM1
YLR229C CDC42 exocytosis, apical bud growth, isotropic bud growth, pseudohyphal growth, invasive growth, Rho protein signal transduction, signal transduction during conjugation with cellular fusion, establishment of cell polarity (sensu Saccharomyces) ->
exocytosis, bud growth, pseudohyphal growth, colony morphology, small GTPase mediated signal transduction, G-protein coupled receptor protein signaling pathway, conjugation with cellular fusion, organelle organization and biogenesis, perception of chemical substance, sensory perception binding, signal transducer activity ->
binding, signal transducer activity soluble fraction, plasma membrane, bud tip, bud neck, shmoo tip ->
soluble fraction, plasma membrane, site of polarized growth (sensu Fungi), site of polarized growth (sensu Saccharomyces) ABF1, FZF1, INO2, RTS2
Main: DNA replication and chromosome cycle (0.50) binding (0.33) nucleus (0.43) ABF1 (0.20)
Score: 0.32 0.07 0.24 0.000
P-value: 1.797E-02 (DNA replication and chromosome cycle) 1.893E+00 (transferase activity) 1.896E-02 (replication fork) 6.046E-01 (RTS2)

ALPHA1(1) AND SWI5(1) AND ECB(1) AND SCB(1) => SimExpr(YLR272C) OR SimExpr(other) : 7 2

EXPR: (0.188) SWI5 (P < 0.005) ECB (P < 0.002) SCB (P < 0.020) ALPHA1 (P < 0.009)

ORF SYMBOL P F C TF
YLR272C YCS4 mitotic chromosome condensation ->
cell proliferation, cell cycle nuclear condensin complex ->
chromosome, nucleus
YNR067C DSE4 cytokinesis\, completion of separation ->
cell proliferation glucan 1\,3-beta-glucosidase activity ->
hydrolase activity\, acting on glycosyl bonds septum, extracellular ->
septum, extracellular YAP6
YOL011W PLB3 phosphoinositide metabolism, phosphatidylserine catabolism ->
catabolism, lipid metabolism lysophospholipase activity ->
hydrolase activity\, acting on ester bonds extracellular space, plasma membrane ->
extracellular, plasma membrane SWI4
YDR180W SCC2 mitotic sister chromatid cohesion ->
cell proliferation, cell cycle protein kinase activity ->
transferase activity\, transferring phosphorus-containing groups nuclear cohesin complex ->
chromosome, nucleus GLN3, MSN4, ROX1
YHR046C INM1 myo-inositol metabolism ->
alcohol metabolism, carbohydrate metabolism myo-inositol-1(or 4)-monophosphatase activity ->
hydrolase activity\, acting on ester bonds
YKL209C STE6 peptide pheromone export ->
transport ATP-binding cassette (ABC) transporter activity ->
purine nucleotide binding, primary active transporter activity, hydrolase activity\, acting on acid anhydrides integral to plasma membrane, shmoo tip ->
integral to membrane, site of polarized growth (sensu Fungi), plasma membrane MCM1, STE12
|YMR253C| NO SYMBOL MCM1
|YIL024C| NO SYMBOL
YML111W BUL2 protein polyubiquitination, protein monoubiquitination ->
catabolism, protein metabolism PDR1, SMP1, SWI5, YAP5
Main: cell proliferation (0.43) hydrolase activity\, acting on ester bonds (0.40) chromosome (0.40) MCM1 (0.33)
Score: 0.19 0.10 0.30 0.067
P-value: 2.391E-02 (chromosome condensation) 3.682E-01 (hydrolase activity) 1.133E-02 (extracellular) 4.214E-01 (MCM1)

ALPHA1(1) AND ALPHA2(1) AND SWI5(1) AND SCB(1) => SimExpr(YLR272C) OR SimExpr(other) : 10 4

ALPHA1(1) AND ALPHA2(1) AND SFF(1) AND SWI5(1) AND SCB(1) => SimExpr(YLR272C) OR SimExpr(other) : 8 3

ALPHA1(1) AND ALPHA2(1) AND ALPHA1'(1) AND SFF(1) AND SCB(1) => SimExpr(YLR272C) OR SimExpr(other) : 7 3

ALPHA1(1) AND ALPHA2(1) AND ALPHA1'(1) AND SWI5(1) AND SCB(1) => SimExpr(YLR272C) OR SimExpr(other) : 6 1

ALPHA1'(1) AND STE12(1) AND PAC(1) => SimExpr(YPR137W) OR SimExpr(other) : 5 1

ALPHA2(1) AND PAC(1) => SimExpr(YJR070C) OR SimExpr(other) : 16 4

LYS14(1) AND PAC(1) => SimExpr(YJR070C) OR SimExpr(other) : 14 5

ALPHA2(1) AND PAC(1) AND SCB(1) => SimExpr(YJR070C) OR SimExpr(other) : 7 1

LYS14(1) AND ALPHA1'(1) AND PAC(1) => SimExpr(YJR070C) OR SimExpr(other) : 7 2

EXPR: (0.171) LYS14 (P < 0.000) ALPHA1' (P < 0.002) PAC (P < 0.248)

ORF SYMBOL P F C TF
YML093W UTP14 processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
|YOL075C| NO SYMBOL CRZ1, DAL82, SIP4
YJR070C NO SYMBOL GAT3, YAP5
YGR191W HIP1 manganese ion transport, histidine transport ->
transport, organic acid transport histidine transporter activity ->
carboxylic acid transporter activity plasma membrane ->
plasma membrane GLN3, HAP3, HIR2, MBP1, MCM1, REB1, YAP1
|YGR178C| PBP1 mRNA polyadenylation ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism cytoplasm, nucleus ->
cytoplasm, nucleus CIN5, DOT6, MSS11
YHR128W FUR1 pyrimidine salvage ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism uracil phosphoribosyltransferase activity ->
transferase activity\, transferring glycosyl groups CIN5
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding nucleolus ->
nucleus
YDR361C BCP1 ABF1, ARO80, GLN3, HAP5, IXR1, YAP1
YGL099W LSG1 conjugation with cellular fusion, sporulation (sensu Saccharomyces), ribosome nucleus export ->
conjugation, sporulation, cell organization and biogenesis, protein metabolism, transport, sexual reproduction GTPase activity ->
purine nucleotide binding, hydrolase activity\, acting on acid anhydrides cytoplasm ->
cytoplasm PHO4
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.67) RNA binding (0.40) nucleus (0.60) CIN5 YAP1 GLN3 (0.29)
Score: 0.60 0.10 0.40 0.095
P-value: 7.105E-02 (ribosome biogenesis) 8.137E-01 (RNA binding) 3.253E-01 (nucleolus) 1.161E-01 (GLN3)

ALPHA1(1) AND mRRPE(1) AND PAC(1) => SimExpr(YJR070C) OR SimExpr(other) : 22 2

ALPHA2(1) AND mRRPE(1) AND PAC(1) => SimExpr(YJR070C) OR SimExpr(other) : 8 2

EXPR: (0.137) ALPHA2 (P < 0.001) mRRPE (P < 0.004) PAC (P < 0.036)

ORF SYMBOL P F C TF
YJL033W HCA4 35S primary transcript processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleus HIR2, USV1
YJR070C NO SYMBOL GAT3, YAP5
|YPR183W| DPM1 N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
lipid biosynthesis, biosynthesis, membrane lipid metabolism, protein metabolism, lipoprotein metabolism transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
cytoplasm, endomembrane system SWI5
|YNR046W| NO SYMBOL ABF1
YMR049C ERB1 rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RTG3
YKL172W EBP2 rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism nucleolus ->
nucleus ABF1, FZF1, RFX1
YGL029W CGR1 ribosome biogenesis, rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism nucleolus ->
nucleus
YHR128W FUR1 pyrimidine salvage ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism uracil phosphoribosyltransferase activity ->
transferase activity\, transferring glycosyl groups CIN5
YLR222C UTP13 processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex ABF1
YLR249W YEF3 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
translation factor activity\, nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex INO2, INO4
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.75) RNA binding (0.40) nucleus (0.67) ABF1 (0.33)
Score: 0.64 0.20 0.53 0.083
P-value: 8.504E-05 (rRNA processing) 2.076E-01 (transferase activity\, transferring glycosyl groups) 3.152E-03 (nucleolus) 3.037E-01 (ABF1)

ALPHA2(1) AND ALPHA1'(1) AND PAC(1) => SimExpr(YJR070C) OR SimExpr(other) : 8 1

LYS14(1) AND mRRPE(1) AND PAC(1) => SimExpr(YJR070C) : 9

ALPHA1(1) AND mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YJR070C) : 8

ALPHA1(1) AND mRRPE(1) AND PAC(1) => SimExpr(YMR131C) OR SimExpr(other) : 21 3

ALPHA1(1) AND mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YMR131C) : 8

CCA(1) AND PAC(1) => SimExpr(YIL118W) OR SimExpr(other) : 5 2

EXPR: (0.172) CCA (P < 0.001) PAC (P < 0.211)

ORF SYMBOL P F C TF
|YLR049C| NO SYMBOL MBP1, SWI5
YIL118W RHO3 exocytosis, small GTPase mediated signal transduction, establishment of cell polarity (sensu Saccharomyces), actin filament organization ->
secretory pathway, intracellular signaling cascade, cytoplasm organization and biogenesis, vesicle-mediated transport Rho small monomeric GTPase activity, signal transducer activity ->
Rho small monomeric GTPase activity, signal transducer activity intracellular ->
intracellular CIN5, NRG1, PHD1, SKN7, SOK2, YAP6
YJL138C TIF2 translational initiation, regulation of translational initiation ->
macromolecule biosynthesis, protein metabolism translation initiation factor activity, RNA helicase activity ->
translation initiation factor activity, RNA helicase activity intracellular ->
intracellular PHD1
YOR272W YTM1 chromosome organization and biogenesis (sensu Eukarya), ribosomal large subunit biogenesis ->
nuclear organization and biogenesis, cytoplasm organization and biogenesis intracellular ->
intracellular LEU3, PUT3, REB1
YLR002C NOC3 DNA replication initiation, rRNA processing ->
cytoplasm organization and biogenesis, cell cycle, DNA metabolism, RNA metabolism, transcription chromatin binding, protein binding ->
chromatin binding, protein binding intracellular ->
intracellular HIR1, IXR1, RCS1
YPR144C NOC4 ribosome biogenesis ->
cytoplasm organization and biogenesis intracellular ->
intracellular HIR1
|YDR076W| RAD55 meiotic DNA recombinase assembly, DNA recombinase assembly, double-strand break repair via synthesis-dependent strand annealing, double-strand break repair via break-induced replication, double-strand break repair via single-strand annealing ->
mating-type switching/recombination, cell cycle, DNA metabolism protein binding ->
protein binding intracellular ->
intracellular DAL81
Main: cytoplasm organization and biogenesis (0.67) protein binding (0.50) intracellular (1.00) PHD1 HIR1 (0.29)
Score: 0.47 0.17 1.00 0.095
P-value: 2.436E-02 (ribosome biogenesis) 4.242E-01 (protein binding) 2.909E+00 (intracellular) 9.226E-02 (HIR1)

ALPHA1(1) AND PAC(1) AND SCB(1) => SimExpr(YIL118W) OR SimExpr(other) : 17 4

RPN4(1) AND MCM1'(1) AND SCB(1) => SimExpr(YCR061W) : 5

SWI5(1) AND PAC(1) AND SCB(1) => SimExpr(YMR259C) OR SimExpr(other) : 9 3

ALPHA1(1) AND PAC(1) AND SCB(1) => SimExpr(YMR259C) OR SimExpr(other) : 18 3

mRRPE(1) AND PAC(1) => SimExpr(YMR259C) OR SimExpr(other) : 80 5

mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YMR259C) OR SimExpr(other) : 21 1

mRRPE(1) AND PHO4(1) => SimExpr(YMR259C) OR SimExpr(other) : 5 2

EXPR: (0.170) mRRPE (P < 0.147) PHO4 (P < 0.027)

ORF SYMBOL P F C TF
|YOR006C| NO SYMBOL
YGR200C ELP2 regulation of transcription from Pol II promoter ->
regulation of transcription, transcription\, DNA-dependent Pol II transcription elongation factor activity ->
Pol II transcription elongation factor activity transcription elongation factor complex ->
nucleus YJL206C
YHR089C GAR1 rRNA modification, 35S primary transcript processing ->
RNA processing, ribosome biogenesis and assembly, rRNA metabolism, transcription\, DNA-dependent RNA binding ->
RNA binding nucleolus, small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex CBF1, FZF1
YML018C NO SYMBOL
YMR259C NO SYMBOL ARG80, GCR2, GTS1, HIR1, SRD1
|YMR042W| ARG80 positive regulation of transcription from Pol II promoter, arginine metabolism ->
amino acid metabolism, regulation of transcription, urea cycle intermediate metabolism, transcription\, DNA-dependent DNA binding, specific RNA polymerase II transcription factor activity ->
DNA binding, specific RNA polymerase II transcription factor activity nucleus ->
nucleus RME1
YGR233C PHO81 phosphate metabolism ->
phosphate metabolism cyclin-dependent protein kinase inhibitor activity ->
cyclin-dependent protein kinase inhibitor activity CAD1, CIN5, HIR2, INO4, PHD1
Main: transcription\, DNA-dependent (0.75) specific RNA polymerase II transcription factor activity (0.25) nucleus (1.00) GCR2 (0.20)
Score: 0.50 0.00 1.00 0.000
P-value: 3.006E-01 (regulation of transcription from Pol II promoter) 5.709E-01 (transcription regulator activity) 2.273E+00 (nucleus) 1.000E+00

mRRPE(1) AND SWI5(1) AND PAC(1) => SimExpr(YMR259C) OR SimExpr(other) : 15 2

SFF(1) AND mRRPE(1) AND PAC(1) => SimExpr(YMR259C) OR SimExpr(other) : 34 3

ALPHA1(1) AND mRRPE(1) AND PAC(1) => SimExpr(YMR259C) OR SimExpr(other) : 23 1

LYS14(1) AND mRRPE(1) AND PAC(1) => SimExpr(YMR259C) : 9

ALPHA1(1) AND mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YMR259C) : 8

mRRPE(1) AND SWI5(1) AND PAC(1) AND SCB(1) => SimExpr(YMR259C) : 6

SFF(1) AND mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YMR259C) : 11

LYS14(1) AND SFF(1) AND mRRPE(1) AND SCB(1) => SimExpr(YMR259C) : 5

ALPHA2(1) AND ALPHA1'(1) AND mRRPE(1) => SimExpr(YLR222C) OR SimExpr(other) : 15 7

ALPHA1'(1) AND SFF'(1) AND PAC(1) => SimExpr(YLR222C) OR SimExpr(other) : 41 18

EXPR: (0.175) ALPHA1' (P < 0.000) SFF' (P < 0.000) PAC (P < 0.537)

ALPHA2(1) AND ALPHA1'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YLR222C) OR SimExpr(other) : 6 1

EXPR: (0.132) ALPHA2 (P < 0.000) ALPHA1' (P < 0.002) mRRPE (P < 0.041) PAC (P < 0.249)

ORF SYMBOL P F C TF
YJL033W HCA4 35S primary transcript processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides nucleolus ->
nucleolus HIR2, USV1
YJR070C NO SYMBOL GAT3, YAP5
|YPR183W| DPM1 N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis ->
lipid biosynthesis, biosynthesis, membrane lipid metabolism, protein metabolism, lipoprotein metabolism transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity ->
transferase activity\, transferring glycosyl groups endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network ->
endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network SWI5
YMR049C ERB1 rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RTG3
YGL029W CGR1 ribosome biogenesis, rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism nucleolus ->
nucleolus
YHR128W FUR1 pyrimidine salvage ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism uracil phosphoribosyltransferase activity ->
transferase activity\, transferring glycosyl groups CIN5
YLR222C UTP13 processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleolus, ribonucleoprotein complex ABF1
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.83) RNA binding (0.50) nucleolus (0.75) ABF1 (0.17)
Score: 0.73 0.33 0.50 0.000
P-value: 3.894E-04 (rRNA processing) 1.018E-01 (transferase activity\, transferring glycosyl groups) 1.112E-02 (nucleolus) 6.777E-01 (USV1)

ALPHA1'(1) AND SFF'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YLR222C) OR SimExpr(other) : 26 4

EXPR: (0.122) ALPHA1' (P < 0.000) SFF' (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.014)

ABF1(1) AND PAC(1) => SimExpr(YNR046W) OR SimExpr(other) : 13 3

ALPHA2(1) AND PAC(1) => SimExpr(YNR046W) OR SimExpr(other) : 16 4

ABF1(1) AND mRRPE(1) AND PAC(1) => SimExpr(YNR046W) OR SimExpr(other) : 8 2

EXPR: (0.142) ABF1 (P < 0.001) mRRPE (P < 0.000) PAC (P < 0.053)

mRRPE(1) AND PHO(1) => SimExpr(YDL167C) OR SimExpr(other) : 8 3

ALPHA2(1) AND PAC(1) => SimExpr(YIL096C) OR SimExpr(other) : 17 3

ALPHA2(1) AND PAC(1) AND SCB(1) => SimExpr(YIL096C) : 8

ALPHA2(1) AND ndt80(MSE)(1) => SimExpr(YOL028C) : 5

ALPHA2(1) AND PAC(1) => SimExpr(YLR336C) OR SimExpr(other) : 18 2

ALPHA2(1) AND PAC(1) AND SCB(1) => SimExpr(YLR336C) : 8

ALPHA2(1) AND PAC(1) => SimExpr(YMR049C) OR SimExpr(other) : 18 2

BAS1(1) AND PAC(1) => SimExpr(YMR049C) OR SimExpr(other) : 8 1

ALPHA2(1) AND ndt80(MSE)(1) => SimExpr(YFR032C) : 5

ABF1(1) AND PAC(1) => SimExpr(YGR187C) OR SimExpr(other) : 14 2

ABF1(1) AND SFF'(1) AND PAC(1) => SimExpr(YGR187C) OR SimExpr(other) : 10 1

EXPR: (0.125) ABF1 (P < 0.000) SFF' (P < 0.000) PAC (P < 0.013)

ORF SYMBOL P F C TF
YHR027C RPN1 ubiquitin-dependent protein catabolism ->
macromolecule catabolism, protein metabolism endopeptidase activity, receptor activity ->
peptidase activity, receptor activity proteasome regulatory particle (sensu Eukarya), endoplasmic reticulum, cytoplasm ->
cytoplasm, nucleus
|YOL041C| NOP12 rRNA metabolism ->
RNA metabolism RNA binding ->
RNA binding nucleolus ->
nucleus GTS1, MET31
YNR046W NO SYMBOL ABF1
YNL292W PUS4 tRNA modification ->
RNA metabolism pseudouridylate synthase activity ->
carbon-oxygen lyase activity mitochondrion, nucleus ->
cytoplasm, nucleus RCS1
YNL112W DBP2 RNA helicase activity ->
RNA binding bud neck ->
site of polarized growth (sensu Fungi)
YGR187C HGH1 ABF1, HAP3, HIR1, RCS1, RTG1
YGR283C NO SYMBOL ACE2, RAP1, SMP1
YKL078W DHR2 ribosome biogenesis ->
cytoplasm organization and biogenesis RNA helicase activity ->
RNA binding nucleolus ->
nucleus ABF1
YJL069C UTP18 ABF1
YKL014C NO SYMBOL ABF1
YDR312W SSF2 ribosomal large subunit assembly and maintenance, conjugation with cellular fusion ->
cytoplasm organization and biogenesis, conjugation with cellular fusion rRNA binding ->
RNA binding nucleolus ->
nucleus ABF1, FKH2, INO4, RAP1
Main: cytoplasm organization and biogenesis (0.40) RNA binding (0.67) nucleus (0.83) ABF1 (0.67)
Score: 0.20 0.40 0.67 0.472
P-value: 9.665E-01 (ribosome biogenesis and assembly) 3.365E-02 (RNA helicase activity) 5.457E-02 (nucleolus) 3.589E-04 (ABF1)

ABF1(1) AND SFF(1) AND PAC(1) => SimExpr(YGR187C) OR SimExpr(other) : 7 1

EXPR: (0.125) ABF1 (P < 0.000) SFF (P < 0.000) PAC (P < 0.021)

ORF SYMBOL P F C TF
|YOL041C| NOP12 rRNA metabolism ->
RNA metabolism RNA binding ->
RNA binding nucleolus ->
nucleus GTS1, MET31
YNL292W PUS4 tRNA modification ->
RNA metabolism pseudouridylate synthase activity ->
carbon-oxygen lyase activity mitochondrion, nucleus ->
cytoplasm, nucleus RCS1
YGR187C HGH1 ABF1, HAP3, HIR1, RCS1, RTG1
YGR283C NO SYMBOL ACE2, RAP1, SMP1
YKL078W DHR2 ribosome biogenesis ->
cytoplasm organization and biogenesis RNA helicase activity ->
RNA binding nucleolus ->
nucleus ABF1
YJL069C UTP18 ABF1
YKL014C NO SYMBOL ABF1
YDR312W SSF2 ribosomal large subunit assembly and maintenance, conjugation with cellular fusion ->
cytoplasm organization and biogenesis, conjugation with cellular fusion rRNA binding ->
RNA binding nucleolus ->
nucleus ABF1, FKH2, INO4, RAP1
Main: cytoplasm organization and biogenesis (0.50) RNA binding (0.75) nucleus (1.00) ABF1 (0.62)
Score: 0.33 0.50 1.00 0.429
P-value: 5.379E-01 (ribosome biogenesis and assembly) 9.691E-02 (RNA binding) 1.729E-02 (nucleolus) 7.462E-04 (ABF1)

ABF1(1) AND mRRPE(1) AND PAC(1) => SimExpr(YGR187C) OR SimExpr(other) : 9 1

ABF1(1) AND SFF(1) AND mRRPE(1) => SimExpr(YGR187C) OR SimExpr(other) : 13 6

ABF1(1) AND SFF'(1) AND mRRPE(1) => SimExpr(YGR187C) OR SimExpr(other) : 15 7

EXPR: (0.208) ABF1 (P < 0.022) SFF' (P < 0.001) mRRPE (P < 0.177)

ABF1(1) AND SFF'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YGR187C) : 6

EXPR: (0.130) ABF1 (P < 0.001) SFF' (P < 0.000) mRRPE (P < 0.008) PAC (P < 0.072)

ORF SYMBOL P F C TF
YNR046W NO SYMBOL ABF1
YNL292W PUS4 tRNA modification ->
tRNA modification pseudouridylate synthase activity ->
pseudouridylate synthase activity mitochondrion, nucleus ->
mitochondrion, nucleus RCS1
YNL112W DBP2 RNA helicase activity ->
RNA helicase activity bud neck ->
bud neck
YGR187C HGH1 ABF1, HAP3, HIR1, RCS1, RTG1
YJL069C UTP18 ABF1
YKL014C NO SYMBOL ABF1
Main: tRNA modification (1.00) RNA helicase activity (0.50) mitochondrion (0.50) ABF1 (0.80)
Score: 0.00 0.00 0.00 0.700
P-value: 0.000E+00 2.735E+00 (enzyme activity) 3.000E+00 (cell) 1.340E-03 (ABF1)

RPN4(1) AND MCM1'(1) AND SCB(1) => SimExpr(YHL024W) : 5

ABF1(1) AND PAC(1) => SimExpr(YLR197W) OR SimExpr(other) : 11 5

ABF1(1) AND PAC(1) AND SCB(1) => SimExpr(YLR197W) : 6

SFF'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YNL112W) OR SimExpr(other) : 40 4

ABF1(1) AND PAC(1) => SimExpr(YNL112W) : 16

SFF'(1) AND mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YNL112W) : 13

ABF1(1) AND SFF'(1) AND SCB(1) => SimExpr(YNL292W) OR SimExpr(other) : 21 10

EXPR: (0.203) ABF1 (P < 0.005) SFF' (P < 0.000) SCB (P < 0.002)

Gcr1(1) AND PAC(1) => SimExpr(YNL292W) OR SimExpr(other) : 5 1

ABF1(1) AND PAC(1) => SimExpr(YNL292W) OR SimExpr(other) : 14 2

ABF1(1) AND PAC(1) AND SCB(1) => SimExpr(YNL292W) : 6

ABF1(1) AND PAC(1) => SimExpr(YJL050W) : 16

STE12(1) AND PAC(1) => SimExpr(YNL141W) OR SimExpr(other) : 9 2

LYS14(1) AND mRRPE(1) AND PAC(1) => SimExpr(YGL099W) : 9

LYS14(1) AND PAC(1) => SimExpr(YML093W) OR SimExpr(other) : 13 6

LYS14(1) AND mRRPE(1) AND PAC(1) => SimExpr(YML093W) : 9

LYS14(1) AND SFF(1) AND mRRPE(1) => SimExpr(YOR355W) OR SimExpr(other) : 14 6

EXPR: (0.184) LYS14 (P < 0.000) SFF (P < 0.000) mRRPE (P < 0.046)

ORF SYMBOL P F C TF
|YNL122C| NO SYMBOL ARO80
YMR277W FCP1 protein amino acid dephosphorylation, transcription ->
phosphorus metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism protein phosphatase activity, phosphoric monoester hydrolase activity ->
hydrolase activity\, acting on ester bonds nucleus ->
nucleus
YHR052W CIC1 protein catabolism ->
catabolism, protein metabolism protein binding\, bridging ->
protein binding\, bridging nucleolus, proteasome complex (sensu Eukarya) ->
nucleus, cytoplasm HAP4, MATa1
|YFL039C| ACT1 cytokinesis, exocytosis, endocytosis, response to osmotic stress, vacuole inheritance, mitotic spindle orientation, mitochondrion inheritance, cell wall organization and biogenesis, apical bud growth, isotropic bud growth, establishment of cell polarity (sensu Saccharomyces), protein secretion, vesicle transport along actin filament, cell cycle dependent actin filament reorganization, sporulation (sensu Saccharomyces), histone acetylation, regulation of transcription from Pol II promoter ->
transport, response to osmotic stress, asexual reproduction, protein secretion, sporulation, transcription, protein metabolism, cell organization and biogenesis, transcription\, DNA-dependent, DNA metabolism, cell proliferation structural constituent of cytoskeleton ->
structural constituent of cytoskeleton actin filament, actin cable (sensu Saccharomyces), contractile ring (sensu Saccharomyces), actin cortical patch (sensu Saccharomyces), histone acetyltransferase complex ->
cytoplasm, site of polarized growth (sensu Fungi), nucleus, cell cortex DIG1, ROX1, STE12
YML093W UTP14 processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
YPR074C TKL1 pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism transketolase activity ->
transferase activity\, transferring aldehyde or ketonic groups cytoplasm ->
cytoplasm REB1
YOR355W GDS1 aerobic respiration ->
energy pathways FHL1, GCR1, PHD1, RLM1
|YPL128C| TBF1 loss of chromatin silencing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription DNA binding, transcription factor activity ->
DNA binding nuclear chromosome\, telomeric region, nuclear chromosome, nucleus ->
chromosome, nucleus
YMR259C NO SYMBOL ARG80, GCR2, GTS1, HIR1, SRD1
YGR240C PFK1 glycolysis ->
carbohydrate metabolism, alcohol metabolism, carbohydrate catabolism, energy pathways, catabolism 6-phosphofructokinase activity ->
carbohydrate kinase activity, transferase activity\, transferring phosphorus-containing groups 6-phosphofructokinase complex, cytoplasm ->
cytoplasm GCR1, HIR1, HIR2
YOR063W RPL3 protein biosynthesis, ribosomal large subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex GRF10(Pho2)
|YLR328W| NMA1 nicotinamide adenine dinucleotide metabolism ->
coenzymes and prosthetic group metabolism, vitamin metabolism nicotinamide-nucleotide adenylyltransferase activity ->
transferase activity\, transferring phosphorus-containing groups CIN5, MSN1, ROX1
YDL140C RPO21 transcription from Pol II promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism DNA-directed RNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups DNA-directed RNA polymerase II\, core complex ->
nucleus REB1
|YJR129C| NO SYMBOL DOT6, SIP4
YNL102W POL1 DNA replication\, priming, DNA replication initiation, lagging strand elongation, DNA repair synthesis ->
DNA metabolism, cell proliferation alpha DNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups alpha DNA polymerase\:primase complex ->
nucleus LEU3, MBP1
YMR290C HAS1 nucleolus, nuclear membrane ->
nucleus, endomembrane system RAP1
YPL032C SVL3 endocytosis ->
transport FKH1, HSF1
YBL092W RPL32 protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, RAP1
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding nucleolus ->
nucleus
|YAL016W| TPD3 protein biosynthesis, actin filament organization, mitotic spindle checkpoint, bud growth, protein amino acid dephosphorylation ->
biosynthesis, cell organization and biogenesis, asexual reproduction, phosphorus metabolism, cell proliferation, cell cycle, protein metabolism protein phosphatase type 2A activity ->
hydrolase activity\, acting on ester bonds protein phosphatase type 2A complex, bud neck, nucleus, cytoplasm, shmoo tip, bud tip, spindle pole body ->
protein phosphatase type 2A complex, nucleus, site of polarized growth (sensu Fungi), site of polarized growth (sensu Saccharomyces), cytoplasm, microtubule organizing center ABF1
Main: cell organization and biogenesis (0.38) transferase activity\, transferring phosphorus-containing groups (0.29) nucleus (0.71) RAP1 ROX1 GCR1 REB1 FHL1 HIR1 (0.12)
Score: 0.35 0.10 0.71 0.050
P-value: 5.747E-01 (protein amino acid dephosphorylation) 6.260E-02 (nucleotidyltransferase activity) 1.347E-01 (nucleolus) 5.330E-01 (GCR1)

LYS14(1) AND SFF(1) AND mRRPE(1) AND SCB(1) => SimExpr(YOR355W) : 5

LYS14(1) AND PAC(1) => SimExpr(YDR361C) OR SimExpr(other) : 13 6

SFF(1) AND mRRPE(1) AND PAC(1) => SimExpr(YHR052W) OR SimExpr(other) : 33 4

SFF'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YHR052W) OR SimExpr(other) : 39 5

LYS14(1) AND SFF(1) AND mRRPE(1) => SimExpr(YHR052W) OR SimExpr(other) : 14 6

LYS14(1) AND mRRPE(1) AND PAC(1) => SimExpr(YHR052W) : 9

LYS14(1) AND SFF(1) AND mRRPE(1) AND SCB(1) => SimExpr(YHR052W) : 5

SFF(1) AND mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YHR052W) : 11

SFF'(1) AND mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YHR052W) : 13

SFF'(1) AND BAS1(1) AND PAC(1) => SimExpr(YLR276C) : 7

EXPR: (0.102) SFF' (P < 0.000) BAS1 (P < 0.000) PAC (P < 0.040)

ORF SYMBOL P F C TF
YIL066C RNR3 DNA replication ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ribonucleoside-diphosphate reductase activity ->
ribonucleoside-diphosphate reductase activity cytoplasm ->
cytoplasm RFX1, STB1
YNR024W NO SYMBOL
YCL059C KRR1 ribosome biogenesis, rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism nucleolus ->
nucleus
YCR090C NO SYMBOL
YBR104W YMC2 transport ->
transport transporter activity ->
transporter activity mitochondrial inner membrane ->
cytoplasm, inner membrane FKH1, FKH2
YOL022C NO SYMBOL MAC1, MOT3, RTS2
YLR276C DBP9 ribosomal large subunit assembly and maintenance, 35S primary transcript processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ATP dependent RNA helicase activity ->
ATP dependent RNA helicase activity nucleolus ->
nucleus MATa1, RCS1, RTG3, SWI5
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.75) ATP dependent RNA helicase activity (0.33) cytoplasm (0.50) RTS2 (0.25)
Score: 0.50 0.00 0.33 0.000
P-value: 2.735E-01 (rRNA processing) 2.856E+00 (enzyme activity) 1.997E-01 (nucleolus) 7.308E-01 (RTS2)

mRRPE(1) AND BAS1(1) AND PAC(1) => SimExpr(YLR276C) : 7

EXPR: (0.102) mRRPE (P < 0.001) BAS1 (P < 0.000) PAC (P < 0.061)

ORF SYMBOL P F C TF
YNR024W NO SYMBOL
YMR049C ERB1 rRNA processing ->
rRNA processing RTG3
YCL059C KRR1 ribosome biogenesis, rRNA processing ->
ribosome biogenesis, rRNA processing nucleolus ->
nucleolus
YCR090C NO SYMBOL
YBR104W YMC2 transport ->
transport transporter activity ->
transporter activity mitochondrial inner membrane ->
mitochondrial inner membrane FKH1, FKH2
YOL022C NO SYMBOL MAC1, MOT3, RTS2
YLR276C DBP9 ribosomal large subunit assembly and maintenance, 35S primary transcript processing ->
ribosomal subunit assembly, rRNA processing ATP dependent RNA helicase activity ->
ATP dependent RNA helicase activity nucleolus ->
nucleolus MATa1, RCS1, RTG3, SWI5
Main: rRNA processing (0.75) ATP dependent RNA helicase activity (0.50) nucleolus (0.67) RTG3 (0.50)
Score: 0.50 0.00 0.33 0.167
P-value: 1.302E-02 (rRNA processing) 2.000E+00 1.712E-01 (nucleolus) 3.263E-02 (RTG3)

SFF(1) AND BAS1(1) AND PAC(1) => SimExpr(YLR276C) : 6

EXPR: (0.103) SFF (P < 0.000) BAS1 (P < 0.000) PAC (P < 0.072)

ORF SYMBOL P F C TF
YNR024W NO SYMBOL
YCL059C KRR1 ribosome biogenesis, rRNA processing ->
ribosome biogenesis, rRNA processing nucleolus ->
nucleolus
YCR090C NO SYMBOL
YBR104W YMC2 transport ->
transport transporter activity ->
transporter activity mitochondrial inner membrane ->
mitochondrial inner membrane FKH1, FKH2
YOL022C NO SYMBOL MAC1, MOT3, RTS2
YLR276C DBP9 ribosomal large subunit assembly and maintenance, 35S primary transcript processing ->
ribosomal subunit assembly, rRNA processing ATP dependent RNA helicase activity ->
ATP dependent RNA helicase activity nucleolus ->
nucleolus MATa1, RCS1, RTG3, SWI5
Main: rRNA processing (0.67) ATP dependent RNA helicase activity (0.50) nucleolus (0.67) RTS2 (0.33)
Score: 0.33 0.00 0.33 0.000
P-value: 1.990E-01 (rRNA processing) 2.000E+00 1.255E-01 (nucleolus) 5.149E-01 (RTS2)

ALPHA1'(1) AND BAS1(1) AND PAC(1) => SimExpr(YLR276C) : 8

EXPR: (0.102) ALPHA1' (P < 0.000) BAS1 (P < 0.000) PAC (P < 0.042)

ORF SYMBOL P F C TF
YIL066C RNR3 DNA replication ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ribonucleoside-diphosphate reductase activity ->
ribonucleoside-diphosphate reductase activity cytoplasm ->
cytoplasm RFX1, STB1
YNR024W NO SYMBOL
YMR049C ERB1 rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RTG3
YCL059C KRR1 ribosome biogenesis, rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism nucleolus ->
nucleus
YCR090C NO SYMBOL
YBR104W YMC2 transport ->
transport transporter activity ->
transporter activity mitochondrial inner membrane ->
cytoplasm, inner membrane FKH1, FKH2
YOL022C NO SYMBOL MAC1, MOT3, RTS2
YLR276C DBP9 ribosomal large subunit assembly and maintenance, 35S primary transcript processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism ATP dependent RNA helicase activity ->
ATP dependent RNA helicase activity nucleolus ->
nucleus MATa1, RCS1, RTG3, SWI5
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.80) ATP dependent RNA helicase activity (0.33) cytoplasm (0.50) RTG3 (0.40)
Score: 0.60 0.00 0.33 0.100
P-value: 2.040E-02 (rRNA processing) 2.923E+00 (enzyme activity) 2.596E-01 (nucleolus) 5.271E-02 (RTG3)

mRRPE(1) AND BAS1(1) AND PAC(1) => SimExpr(YNR024W) OR SimExpr(other) : 6 1

SFF'(1) AND BAS1(1) AND PAC(1) => SimExpr(YNR024W) OR SimExpr(other) : 6 1

ALPHA1'(1) AND BAS1(1) AND PAC(1) => SimExpr(YNR024W) OR SimExpr(other) : 7 1

SFF(1) AND BAS1(1) AND PAC(1) => SimExpr(YNR024W) OR SimExpr(other) : 5 1

mRRPE(1) AND BAS1(1) AND PAC(1) => SimExpr(YBR104W) OR SimExpr(other) : 5 2

SFF(1) AND mRRPE(1) AND PAC(1) => SimExpr(YOR078W) OR SimExpr(other) : 34 3

SFF'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YOR078W) OR SimExpr(other) : 39 5

PDR(1) AND PAC(1) => SimExpr(YOR078W) OR SimExpr(other) : 6 2

EXPR: (0.164) PDR (P < 0.000) PAC (P < 0.503)

ORF SYMBOL P F C TF
YOL041C NOP12 rRNA metabolism ->
RNA metabolism RNA binding ->
RNA binding nucleolus ->
nucleolus GTS1, MET31
|YHR083W| NO SYMBOL DIG1, STE12
YDR365C NO SYMBOL ABF1, MSS11, YJL206C
|YNL277W| MET2 methionine biosynthesis, homoserine metabolism ->
amine biosynthesis, amino acid metabolism, sulfur metabolism homoserine O-acetyltransferase activity ->
transferase activity\, transferring acyl groups cytoplasm ->
cytoplasm CBF1, MET31, MET4, STE12
YPL068C NO SYMBOL CBF1
YML125C NO SYMBOL MAL13, MSN4, NDD1, RME1, SWI5
YOR078W BUD21 processing of 20S pre-rRNA ->
cytoplasm organization and biogenesis, RNA metabolism, transcription snoRNA binding ->
RNA binding small nucleolar ribonucleoprotein complex ->
nucleolus, ribonucleoprotein complex ABF1, MSS11, SIG1, SKO1
YDR361C BCP1 ABF1, ARO80, GLN3, HAP5, IXR1, YAP1
Main: RNA metabolism (0.67) RNA binding (0.67) nucleolus (0.67) ABF1 (0.38)
Score: 0.33 0.33 0.33 0.214
P-value: 6.760E-01 (RNA metabolism) 5.529E-01 (RNA binding) 2.225E-01 (nucleolus) 9.070E-02 (MET31)

SFF'(1) AND mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YOR078W) : 13

SFF(1) AND mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YOR078W) : 11

SFF'(1) AND mRRPE(1) AND PAC(1) => SimExpr(YCL059C) OR SimExpr(other) : 39 5

SFF(1) AND mRRPE(1) AND PAC(1) => SimExpr(YCL059C) OR SimExpr(other) : 34 3

BAS1(1) AND PAC(1) => SimExpr(YCL059C) OR SimExpr(other) : 8 1

SFF'(1) AND BAS1(1) AND PAC(1) => SimExpr(YCL059C) : 7

mRRPE(1) AND BAS1(1) AND PAC(1) => SimExpr(YCL059C) : 7

SFF(1) AND BAS1(1) AND PAC(1) => SimExpr(YCL059C) : 6

ALPHA1'(1) AND BAS1(1) AND PAC(1) => SimExpr(YCL059C) : 8

SFF(1) AND mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YCL059C) : 11

SFF'(1) AND mRRPE(1) AND PAC(1) AND SCB(1) => SimExpr(YCL059C) : 13

STE12(1) AND PAC(1) => SimExpr(YGR158C) OR SimExpr(other) : 9 2

ALPHA1'(1) AND STE12(1) AND PAC(1) => SimExpr(YGR158C) OR SimExpr(other) : 5 1

SFF'(1) AND STE12(1) AND PAC(1) => SimExpr(YGR158C) OR SimExpr(other) : 5 1

SFF(1) AND mRRPE(1) AND ALPHA2'(1) => SimExpr(YJR025C) OR SimExpr(other) : 5 2

EXPR: (0.221) SFF (P < 0.009) mRRPE (P < 0.106) ALPHA2' (P < 0.016)

ORF SYMBOL P F C TF
|YNL122C| NO SYMBOL ARO80
YJR025C BNA1 nicotinamide adenine dinucleotide biosynthesis ->
coenzymes and prosthetic group metabolism, biosynthesis, water-soluble vitamin metabolism, vitamin metabolism 3-hydroxyanthranilate 3\,4-dioxygenase activity ->
3-hydroxyanthranilate 3\,4-dioxygenase activity cytoplasm ->
cytoplasm GCN4, SUM1, SWI6
YPR117W NO SYMBOL IME4, MBP1, SFP1
YLR175W CBF5 rRNA modification, 35S primary transcript processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription pseudouridylate synthase activity ->
pseudouridylate synthase activity small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex AZF1, HAL9
|YOR295W| UAF30 transcription from Pol I promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA polymerase I transcription factor activity, ribosomal DNA (rDNA) binding ->
RNA polymerase I transcription factor activity, ribosomal DNA (rDNA) binding RNA polymerase I upstream activating factor complex ->
nucleus
YBL092W RPL32 protein biosynthesis ->
biosynthesis, protein metabolism structural constituent of ribosome ->
structural constituent of ribosome cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex FHL1, RAP1
YDR119W NO SYMBOL MSS11, SIG1, SKO1
Main: biosynthesis (0.50) ribosomal DNA (rDNA) binding (0.25) cytoplasm (0.50) AZF1 (0.17)
Score: 0.33 0.00 0.50 0.000
P-value: 2.039E-01 (transcription from Pol I promoter) 2.856E+00 (enzyme activity) 2.282E-01 (nucleolus) 9.945E-01 (SKO1)

mRRPE(1) AND STE12(1) AND PAC(1) => SimExpr(YAL059W) : 5

mRRPE(1) AND PAC(1) => SimExpr(YML125C) OR SimExpr(other) : 60 25

mRRPE(1) AND SWI5(1) AND PAC(1) AND MCM1'(1) => SimExpr(YML125C) : 5

EXPR: (0.143) mRRPE (P < 0.002) SWI5 (P < 0.000) PAC (P < 0.004) MCM1' (P < 0.000)

ORF SYMBOL P F C TF
YDR399W HPT1 purine nucleotide biosynthesis ->
biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism hypoxanthine phosphoribosyltransferase activity ->
hypoxanthine phosphoribosyltransferase activity
YOR310C NOP58 rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex ->
small nuclear ribonucleoprotein complex, nucleolus, ribonucleoprotein complex ABF1, SWI6
YML125C NO SYMBOL MAL13, MSN4, NDD1, RME1, SWI5
YDR279W RNH202 GCR2, MBP1, RIM101, RLM1, SWI6, THI2
YGR280C PXR1 35S primary transcript processing, snRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism RNA binding ->
RNA binding nucleolus ->
nucleolus
Main: nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (1.00) hypoxanthine phosphoribosyltransferase activity (0.50) nucleolus (1.00) SWI6 (0.67)
Score: 1.00 0.00 1.00 0.333
P-value: 2.654E-02 (35S primary transcript processing) 2.000E+00 8.582E-02 (nucleolus) 8.946E-02 (SWI6)

SFF'(1) AND GCN4(1) AND Leu3(1) => SimExpr(YJR016C) : 5

EXPR: (0.110) SFF' (P < 0.000) GCN4 (P < 0.002) Leu3 (P < 0.003)

ORF SYMBOL P F C TF
YJR016C ILV3 branched chain family amino acid biosynthesis ->
amino acid biosynthesis, branched chain family amino acid metabolism dihydroxy-acid dehydratase activity ->
hydro-lyase activity mitochondrion ->
cytoplasm
YLR355C ILV5 branched chain family amino acid biosynthesis, mitochondrial genome maintenance ->
amino acid biosynthesis, mitochondrion organization and biogenesis, branched chain family amino acid metabolism ketol-acid reductoisomerase activity ->
oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor mitochondrion ->
cytoplasm GCN4, MET4
YGL009C LEU1 leucine biosynthesis ->
amino acid biosynthesis, branched chain family amino acid metabolism 3-isopropylmalate dehydratase activity ->
hydro-lyase activity cytosol ->
cytoplasm LEU3
YDR158W HOM2 homoserine biosynthesis, threonine metabolism, methionine metabolism ->
amino acid biosynthesis, aspartate family amino acid metabolism, homoserine metabolism, serine family amino acid metabolism, sulfur amino acid metabolism aspartate-semialdehyde dehydrogenase activity ->
oxidoreductase activity\, acting on the aldehyde or oxo group of donors\, NAD or NADP as acceptor ACE2, HSF1, NDD1, REB1, SKN7, SWI5
YOR108W LEU9 leucine biosynthesis ->
amino acid biosynthesis, branched chain family amino acid metabolism 2-isopropylmalate synthase activity ->
oxo-acid-lyase activity mitochondrion ->
cytoplasm AZF1, GCN4, LEU3
Main: amino acid biosynthesis (1.00) hydro-lyase activity (0.40) cytoplasm (1.00) LEU3 GCN4 (0.50)
Score: 1.00 0.10 1.00 0.333
P-value: 1.808E-08 (branched chain family amino acid biosynthesis) 2.482E-03 (lyase activity) 1.074E-01 (mitochondrion) 1.038E-02 (LEU3)

mRRPE(1) AND zap1(1) => SimExpr(YKR059W) OR SimExpr(other) : 8 3

EXPR: (0.188) mRRPE (P < 0.191) zap1 (P < 0.003)

ORF SYMBOL P F C TF
YNL189W SRP1 nucleocytoplasmic transport ->
transport protein carrier activity ->
protein carrier activity nucleus, cytoplasm ->
nucleus, cytoplasm ABF1, MOT3
YPR117W NO SYMBOL IME4, MBP1, SFP1
YKR079C NO SYMBOL BAS1
YKR059W TIF1 translational initiation ->
biosynthesis, protein metabolism translation initiation factor activity ->
translation factor activity\, nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex ABF1, FKH1, FKH2
|YNR060W| FRE4 iron-siderochrome transport ->
transport ferric-chelate reductase activity ->
oxidoreductase activity\, oxidizing metal ions plasma membrane ->
plasma membrane NRG1
YLR130C ZRT2 low-affinity zinc ion transport ->
transport low-affinity zinc ion transporter activity ->
cation transporter activity, metal ion transporter activity plasma membrane ->
plasma membrane ZAP1
YMR130W NO SYMBOL
YPR080W TEF1 translational elongation ->
biosynthesis, protein metabolism translation elongation factor activity ->
translation factor activity\, nucleic acid binding ribosome ->
cytoplasm, ribonucleoprotein complex FHL1, PDR1, RAP1, YAP5
YLR355C ILV5 branched chain family amino acid biosynthesis, mitochondrial genome maintenance ->
amine metabolism, cell organization and biogenesis, amino acid and derivative metabolism, organic acid metabolism, biosynthesis ketol-acid reductoisomerase activity ->
oxidoreductase activity\, acting on CH-OH group of donors mitochondrion ->
cytoplasm GCN4, MET4
|YCR044C| PER1 manganese ion homeostasis, response to unfolded protein ->
response to biotic stimulus, cell homeostasis vacuolar membrane (sensu Fungi) ->
cytoplasm, vacuole YFL044C
|YJR122W| CAF17 YAP1
Main: biosynthesis (0.43) translation factor activity\, nucleic acid binding (0.33) cytoplasm (0.71) ABF1 (0.20)
Score: 0.29 0.07 0.52 0.022
P-value: 3.837E+00 (protein biosynthesis) 1.679E-01 (translation factor activity\, nucleic acid binding) 1.863E+00 (plasma membrane) 1.000E+00

mRRPE(1) AND PAC(1) => SimExpr(YHR089C) OR SimExpr(other) : 73 12

mRRPE(1) AND STE12(1) AND PAC(1) => SimExpr(YMR310C) : 5

mRRPE(1) AND STE12(1) AND PAC(1) => SimExpr(YBR247C) : 5

AVERAGE SCORES:

P
  SCORE: 0.505 (Part of genes covered by "Main": 0.640) (No. rules=147/150)
  P-VALUE: 0.429
F
  SCORE: 0.212 (Part of genes covered by "Main": 0.452) (No. rules=139/150)
  P-VALUE: 0.302
C
  SCORE: 0.611 (Part of genes covered by "Main": 0.724) (No. rules=142/150)
  P-VALUE: 0.444
TF
  SCORE: 0.246 (Part of genes covered by "Main": 0.431) (No. rules=148/150)
  P-VALUE: 0.291
EXPRESSION: 0.533 (150)

ORF	SYMBOL	P	F	C	TF
YCR061W	NO SYMBOL				HSF1
YGR142W	BTN2	regulation of pH, intracellular protein transport -> regulation of pH, intracellular protein transport		cytosol -> cytoplasm	HSF1, MSN4
YJL045W	NO SYMBOL				MBP1, ROX1
YHL024W	RIM4	sporulation, meiosis, premeiotic DNA synthesis, meiotic recombination -> sporulation, meiosis, premeiotic DNA synthesis, meiotic recombination	RNA binding -> RNA binding	cytoplasm -> cytoplasm	FKH2, PHD1
YGL096W	TOS8		transcription factor activity -> transcription factor activity		IXR1, SOK2, SWI4
Main:		premeiotic DNA synthesis (0.50)	RNA binding (0.50)	cytoplasm (1.00)	HSF1 (0.40)
Score:		0.00	0.00	1.00	0.100
P-value:		4.252E+00 (cell growth and/or maintenance)	7.667E-01 (nucleic acid binding)	4.409E+00 (cytoplasm)	5.771E-02 (HSF1)

ORF	SYMBOL	P	F	C	TF
YIL096C	NO SYMBOL				GAT3, HAP2, MOT3, RTS2
YJR070C	NO SYMBOL				GAT3, YAP5
YHR027C	RPN1	ubiquitin-dependent protein catabolism -> catabolism, protein metabolism	endopeptidase activity, receptor activity -> peptidase activity, receptor activity	proteasome regulatory particle (sensu Eukarya), endoplasmic reticulum, cytoplasm -> cytoplasm, nucleus
YDR364C	CDC40	DNA replication, S phase of mitotic cell cycle, mRNA splicing, mitotic spindle assembly (sensu Saccharomyces) -> cytoplasm organization and biogenesis, cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, M phase	nucleic acid binding, pre-mRNA splicing factor activity -> nucleic acid binding	spliceosome complex, nuclear membrane, nuclear pore -> nucleus, ribonucleoprotein complex, membrane
YKL172W	EBP2	rRNA processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism		nucleolus -> nucleus	ABF1, FZF1, RFX1
\|YML108W\|	NO SYMBOL
YLR336C	SGD1	osmoregulation -> osmoregulation		nucleus -> nucleus
YFL007W	BLM3			membrane -> membrane
YLR222C	UTP13	processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> nucleic acid binding	small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	ABF1
YJL033W	HCA4	35S primary transcript processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ATP dependent RNA helicase activity -> nucleic acid binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleolus -> nucleus	HIR2, USV1
YGL029W	CGR1	ribosome biogenesis, rRNA processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism		nucleolus -> nucleus
\|YPR183W\|	DPM1	N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis -> lipid biosynthesis, biosynthesis, membrane lipid metabolism, protein metabolism, lipoprotein metabolism	transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity -> transferase activity\, transferring glycosyl groups	endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network -> cytoplasm, membrane	SWI5
YNR046W	NO SYMBOL				ABF1
YDR312W	SSF2	ribosomal large subunit assembly and maintenance, conjugation with cellular fusion -> cell organization and biogenesis, conjugation, sexual reproduction	rRNA binding -> nucleic acid binding	nucleolus -> nucleus	ABF1, FKH2, INO4, RAP1
YMR049C	ERB1	rRNA processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism			RTG3
YNL023C	FAP1		transcription factor activity -> nucleic acid binding
\|YOR284W\|	HUA2				RFX1, YAP6
YHR128W	FUR1	pyrimidine salvage -> biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	uracil phosphoribosyltransferase activity -> transferase activity\, transferring glycosyl groups		CIN5
YPL106C	SSE1	protein folding -> protein metabolism	co-chaperone activity -> co-chaperone activity	cytoplasm -> cytoplasm	HSF1, MSN4
YLR249W	YEF3	translational elongation -> biosynthesis, protein metabolism	translation elongation factor activity -> nucleic acid binding	ribosome -> cytoplasm, ribonucleoprotein complex	INO2, INO4
Main:		nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.54)	nucleic acid binding (0.60)	nucleus (0.67)	ABF1 (0.31)
Score:		0.44	0.36	0.59	0.115
P-value:		3.866E-03 (ribosome biogenesis and assembly)	4.710E-01 (RNA binding)	8.984E-03 (nucleolus)	7.648E-01 (GAT3)

ORF	SYMBOL	P	F	C	TF
\|YMR094W\|	CTF13	centromere/kinetochore complex maturation -> cell proliferation	centromeric DNA binding, DNA bending activity -> nucleic acid binding	condensed nuclear chromosome kinetochore -> intracellular
\|YFL011W\|	HXT10	hexose transport -> transport	glucose transporter activity, fructose transporter activity, mannose transporter activity, galactose transporter activity -> transporter activity	plasma membrane -> membrane	GTS1, MBP1, RTG3
YPR031W	NTO1				MSN2, RCS1
\|YJR055W\|	HIT1	aerobic respiration -> energy pathways			STP2
YHR027C	RPN1	ubiquitin-dependent protein catabolism -> catabolism, protein metabolism	endopeptidase activity, receptor activity -> peptidase activity, signal transducer activity	proteasome regulatory particle (sensu Eukarya), endoplasmic reticulum, cytoplasm -> intracellular
YHR052W	CIC1	protein catabolism -> catabolism, protein metabolism	protein binding\, bridging -> protein binding	nucleolus, proteasome complex (sensu Eukarya) -> intracellular	HAP4, MATa1
YNL132W	KRE33
YHR088W	RPF1	processing of 27S pre-rRNA, ribosomal large subunit assembly and maintenance -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	rRNA primary transcript binding -> nucleic acid binding	nucleolus -> intracellular	FKH1
YOL041C	NOP12	rRNA metabolism -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	RNA binding -> nucleic acid binding	nucleolus -> intracellular	GTS1, MET31
YDR364C	CDC40	DNA replication, S phase of mitotic cell cycle, mRNA splicing, mitotic spindle assembly (sensu Saccharomyces) -> cytoplasm organization and biogenesis, cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, M phase	nucleic acid binding, pre-mRNA splicing factor activity -> nucleic acid binding	spliceosome complex, nuclear membrane, nuclear pore -> intracellular, membrane
\|YHR083W\|	NO SYMBOL				DIG1, STE12
YIL118W	RHO3	exocytosis, small GTPase mediated signal transduction, establishment of cell polarity (sensu Saccharomyces), actin filament organization -> signal transduction, cell organization and biogenesis, transport	Rho small monomeric GTPase activity, signal transducer activity -> purine nucleotide binding, signal transducer activity, hydrolase activity\, acting on acid anhydrides	intracellular -> intracellular	CIN5, NRG1, PHD1, SKN7, SOK2, YAP6
YML043C	RRN11	transcription from Pol I promoter -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	RNA polymerase I transcription factor activity -> RNA polymerase I transcription factor activity	RNA polymerase I transcription factor complex -> intracellular	MAL13
YJL109C	UTP10	processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> nucleic acid binding	small nucleolar ribonucleoprotein complex -> intracellular
YDR101C	ARX1	ribosomal large subunit biogenesis -> cell organization and biogenesis		nucleoplasm, cytoplasm -> intracellular	IXR1, RFX1
\|YLL027W\|	ISA1	iron ion transport -> transport		mitochondrial matrix -> intracellular	HAP2, HAP3, HAP5, HSF1, YAP3
YJL033W	HCA4	35S primary transcript processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ATP dependent RNA helicase activity -> nucleic acid binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleolus -> intracellular	HIR2, USV1
\|YPL149W\|	APG5	protein-vacuolar targeting, autophagy -> cell organization and biogenesis, autophagy, protein metabolism, transport		cytosol -> intracellular
\|YKL142W\|	MRP8	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural molecule activity	mitochondrial ribosome -> intracellular	ACE2, CIN5, MBP1, PHO4, REB1, SKN7, STB1
\|YIL122W\|	POG1	re-entry into mitotic cell cycle after pheromone arrest -> cell proliferation, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus	specific RNA polymerase II transcription factor activity -> specific RNA polymerase II transcription factor activity	nucleus -> intracellular	ASH1, CIN5, NRG1, RLM1, SMP1, YAP6
YGR145W	ENP2
\|YOL075C\|	NO SYMBOL				CRZ1, DAL82, SIP4
YIL066C	RNR3	DNA replication -> cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ribonucleoside-diphosphate reductase activity -> oxidoreductase activity\, acting on CH2 groups	cytoplasm -> intracellular	RFX1, STB1
\|YBR044C\|	TCM62	protein complex assembly -> protein metabolism	chaperone activity -> chaperone activity	mitochondrial inner membrane -> intracellular, membrane	GRF10(Pho2), MCM1
\|YBL066C\|	SEF1
YML005W	NO SYMBOL				USV1
YNL075W	IMP4	rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription	rRNA primary transcript binding -> nucleic acid binding	small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex -> intracellular	USV1
YKR092C	SRP40	nucleocytoplasmic transport -> transport	chaperone activity -> chaperone activity	nucleolus -> intracellular	CUP9, MET4, RAP1
YNL308C	KRI1	ribosome biogenesis -> cell organization and biogenesis		nucleolus -> intracellular
YNR024W	NO SYMBOL
YJL138C	TIF2	translational initiation, regulation of translational initiation -> biosynthesis, protein metabolism	translation initiation factor activity, RNA helicase activity -> nucleic acid binding	ribosome, cytoplasm -> intracellular	PHD1
\|YNL277W\|	MET2	methionine biosynthesis, homoserine metabolism -> amine metabolism, sulfur metabolism, biosynthesis, amino acid and derivative metabolism, organic acid metabolism	homoserine O-acetyltransferase activity -> transferase activity\, transferring acyl groups	cytoplasm -> intracellular	CBF1, MET31, MET4, STE12
\|YPR149W\|	NCE102	protein secretion -> protein secretion		integral to membrane, endoplasmic reticulum, cytoplasm -> membrane, intracellular	CIN5, FKH2, GRF10(Pho2), HSF1, NDD1, PUT3, RAP1, SKN7, SWI4, YAP6
\|YHR146W\|	CRP1		DNA binding -> nucleic acid binding	nucleus -> intracellular	IXR1
YLR073C	NO SYMBOL
YHR169W	DBP8	35S primary transcript processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ATP dependent RNA helicase activity -> nucleic acid binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleolus -> intracellular
YNL299W	TRF5	sister chromatid cohesion -> cell proliferation	DNA-directed DNA polymerase activity -> transferase activity\, transferring phosphorus-containing groups	nucleus -> intracellular
\|YJL105W\|	SET4				ASH1, CIN5, FKH1, MTH1, PHD1, SKN7
YGR251W	NO SYMBOL				MSN4, PHD1, SKN7
\|YPR183W\|	DPM1	N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis -> lipid biosynthesis, biosynthesis, membrane lipid metabolism, protein metabolism, lipoprotein metabolism	transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity -> transferase activity\, transferring glycosyl groups	endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network -> intracellular, membrane	SWI5
YNR046W	NO SYMBOL				ABF1
YNL292W	PUS4	tRNA modification -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	pseudouridylate synthase activity -> carbon-oxygen lyase activity	mitochondrion, nucleus -> intracellular	RCS1
YGR245C	SDA1	actin cytoskeleton organization and biogenesis, start control point of mitotic cell cycle -> cell organization and biogenesis, cell proliferation		nucleus -> intracellular
YNL112W	DBP2		RNA helicase activity -> nucleic acid binding	bud neck -> site of polarized growth (sensu Fungi)
YCL059C	KRR1	ribosome biogenesis, rRNA processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism		nucleolus -> intracellular
\|YCR090C\|	NO SYMBOL
\|YGR191W\|	HIP1	manganese ion transport, histidine transport -> transport, organic acid transport	histidine transporter activity -> transporter activity	plasma membrane -> membrane	GLN3, HAP3, HIR2, MBP1, MCM1, REB1, YAP1
YOR359W	VTS1	protein-vacuolar targeting -> cell organization and biogenesis, protein metabolism, transport	intracellular transporter activity -> transporter activity	cytosol -> intracellular	RAP1
\|YGR178C\|	PBP1	mRNA polyadenylation -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism		cytoplasm, nucleus -> intracellular	CIN5, DOT6, MSS11
YCR016W	NO SYMBOL
YNL163C	RIA1	ribosome biogenesis -> cell organization and biogenesis	translation elongation factor activity -> nucleic acid binding	cytoplasm -> intracellular	FHL1, RAP1, YAP5
\|YBR292C\|	NO SYMBOL				STE12, ZMS1
YGR187C	HGH1				ABF1, HAP3, HIR1, RCS1, RTG1
YCR072C	NO SYMBOL				YFL044C
YGL078C	DBP3	ribosomal large subunit assembly and maintenance, 35S primary transcript processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ATP dependent RNA helicase activity -> nucleic acid binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleolus -> intracellular
YKL056C	NO SYMBOL
YGL016W	KAP122	protein-nucleus import, response to drug -> response to abiotic stimulus, protein metabolism, transport	protein carrier activity -> transporter activity	cytoplasm, nuclear pore -> intracellular, membrane	MSN2
\|YIR026C\|	YVH1	meiosis, sporulation (sensu Saccharomyces) -> cell proliferation, sporulation	protein tyrosine phosphatase activity -> hydrolase activity\, acting on ester bonds		DOT6, SUM1
YML108W	NO SYMBOL
YGR283C	NO SYMBOL				ACE2, RAP1, SMP1
YLR221C	RSA3
YBR104W	YMC2	transport -> transport	transporter activity -> transporter activity	mitochondrial inner membrane -> intracellular, membrane	FKH1, FKH2
YKL078W	DHR2	ribosome biogenesis -> cell organization and biogenesis	RNA helicase activity -> nucleic acid binding	nucleolus -> intracellular	ABF1
YGL029W	CGR1	ribosome biogenesis, rRNA processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism		nucleolus -> intracellular
YDR384C	ATO3	transport, nitrogen utilization -> transport, nitrogen metabolism	transporter activity -> transporter activity	membrane -> membrane	ABF1, FHL1, INO4
YNL023C	FAP1		transcription factor activity -> nucleic acid binding
YOR310C	NOP58	rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription		small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex -> intracellular	ABF1, SWI6
\|YDR017C\|	KCS1	vacuole organization and biogenesis, response to stress -> cell organization and biogenesis, response to stress	inositol/phosphatidylinositol kinase activity -> transferase activity\, transferring phosphorus-containing groups
YPR137W	RRP9	rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription	snoRNA binding -> nucleic acid binding	small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex -> intracellular	ABF1, HIR1, RCS1
YOR381W	FRE3	iron-siderochrome transport, iron ion homeostasis -> transport, cell homeostasis	ferric-chelate reductase activity -> oxidoreductase activity\, oxidizing metal ions	plasma membrane, integral to membrane -> membrane	CIN5, PDR1, YAP6
\|YBR117C\|	TKL2	pentose-phosphate shunt -> coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism	transketolase activity -> transferase activity\, transferring aldehyde or ketonic groups		FHL1, RAP1
YML125C	NO SYMBOL				MAL13, MSN4, NDD1, RME1, SWI5
YNR053C	NOG2	mRNA splicing -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	GTPase activity -> purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleus, nucleolus, nucleoplasm -> intracellular	ABF1, AZF1
\|YIR035C\|	NO SYMBOL				YAP6
\|YJL166W\|	QCR8	aerobic respiration, oxidative phosphorylation\, ubiquinone to cytochrome c -> energy pathways, electron transport, phosphorus metabolism	ubiquinol-cytochrome c reductase activity -> oxidoreductase activity\, acting on diphenols and related substances as donors, transporter activity	respiratory chain complex III (sensu Eukarya) -> intracellular, membrane
YIL026C	IRR1	mitotic sister chromatid cohesion, colony morphology, germination (sensu Saccharomyces), cytogamy -> cell organization and biogenesis, sporulation, plasma membrane fusion, sporulation (sensu Fungi), cell proliferation, conjugation, sexual reproduction	protein binding -> protein binding	nuclear cohesin complex -> intracellular	ABF1, MAL33, MBP1, SWI6
YOR021C	NO SYMBOL				ARG80, GCR2
YOL022C	NO SYMBOL				MAC1, MOT3, RTS2
YMR290C	HAS1			nucleolus, nuclear membrane -> intracellular, membrane	RAP1
\|YLL010C\|	PSR1	response to stress -> response to stress	protein phosphatase activity -> hydrolase activity\, acting on ester bonds	plasma membrane -> membrane	CBF1
YOR078W	BUD21	processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> nucleic acid binding	small nucleolar ribonucleoprotein complex -> intracellular	ABF1, MSS11, SIG1, SKO1
YJL069C	UTP18				ABF1
\|YDR279W\|	RNH202				GCR2, MBP1, RIM101, RLM1, SWI6, THI2
YGR280C	PXR1	35S primary transcript processing, snRNA processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	RNA binding -> nucleic acid binding	nucleolus -> intracellular
\|YOR095C\|	RKI1	pentose-phosphate shunt -> coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism	ribose-5-phosphate isomerase activity -> intramolecular isomerase activity		FHL1, FKH2, RAP1
YLR276C	DBP9	ribosomal large subunit assembly and maintenance, 35S primary transcript processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ATP dependent RNA helicase activity -> nucleic acid binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleolus -> intracellular	MATa1, RCS1, RTG3, SWI5
YGR158C	MTR3	35S primary transcript processing, mRNA catabolism -> cell organization and biogenesis, catabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	3'-5' exoribonuclease activity -> hydrolase activity\, acting on ester bonds, nucleic acid binding	nuclear exosome (RNase complex), cytoplasmic exosome (RNase complex) -> intracellular	ZMS1
YKL014C	NO SYMBOL				ABF1
YML123C	PHO84	phosphate transport -> transport	inorganic phosphate transporter activity -> transporter activity	integral to plasma membrane -> membrane	HIR2
YLR222C	UTP13	processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> nucleic acid binding	small nucleolar ribonucleoprotein complex -> intracellular	ABF1
YGL189C	RPS26A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural molecule activity	cytosolic small ribosomal subunit (sensu Eukarya) -> intracellular	FHL1, GAT3, PDR1, RAP1, RGM1, YAP5
YPL143W	RPL33A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural molecule activity	cytosolic large ribosomal subunit (sensu Eukarya) -> intracellular	FHL1, MET4, NDD1, PDR1, RAP1, RME1
YDR449C	UTP6	processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> nucleic acid binding	small nucleolar ribonucleoprotein complex -> intracellular	FHL1, GAT3, HIR2, RAP1, RGM1, YAP5
YDR361C	BCP1				ABF1, ARO80, GLN3, HAP5, IXR1, YAP1
YDR312W	SSF2	ribosomal large subunit assembly and maintenance, conjugation with cellular fusion -> cell organization and biogenesis, conjugation, sexual reproduction	rRNA binding -> nucleic acid binding	nucleolus -> intracellular	ABF1, FKH2, INO4, RAP1
\|YKL120W\|	OAC1	oxaloacetate transport, sulfate transport -> transport	oxaloacetate carrier activity, sulfate porter activity -> transporter activity	mitochondrial inner membrane -> intracellular, membrane	LEU3, MTH1
YGL092W	NUP145	tRNA splicing, mRNA-nucleus export, rRNA-nucleus export, snRNA-nucleus export, tRNA-nucleus export, protein-nucleus import, NLS-bearing substrate-nucleus import, snRNP protein-nucleus import, mRNA-binding (hnRNP) protein-nucleus import, ribosomal protein-nucleus import, protein-nucleus export, nuclear pore organization and biogenesis -> intracellular transport, intracellular protein transport, cell organization and biogenesis, protein metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein transport	structural molecule activity -> structural molecule activity	nuclear pore -> intracellular, membrane	FKH1
\|YOL141W\|	PPM2		C-terminal protein carboxyl methyltransferase activity -> transferase activity\, transferring one-carbon groups		ARG81, SRD1
\|YPL165C\|	SET6				CIN5
YJL010C	NO SYMBOL
YPL106C	SSE1	protein folding -> protein metabolism	co-chaperone activity -> chaperone activity	cytoplasm -> intracellular	HSF1, MSN4
YLR249W	YEF3	translational elongation -> biosynthesis, protein metabolism	translation elongation factor activity -> nucleic acid binding	ribosome -> intracellular	INO2, INO4
Main:		cell organization and biogenesis (0.42)	nucleic acid binding (0.41)	intracellular (0.89)	ABF1 (0.19)
Score:		0.34	0.20	0.83	0.106
P-value:		3.308E-08 (ribosome biogenesis)	6.981E-04 (RNA helicase activity)	1.233E-12 (nucleolus)	6.270E-01 (ABF1)

ORF	SYMBOL	P	F	C	TF
\|YLR049C\|	NO SYMBOL				MBP1, SWI5
\|YFL011W\|	HXT10	hexose transport -> transport	glucose transporter activity, fructose transporter activity, mannose transporter activity, galactose transporter activity -> hexose transporter activity	plasma membrane -> plasma membrane	GTS1, MBP1, RTG3
YJL109C	UTP10	processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex
YHR089C	GAR1	rRNA modification, 35S primary transcript processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription	RNA binding -> RNA binding	nucleolus, small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	CBF1, FZF1
YDR399W	HPT1	purine nucleotide biosynthesis -> biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	hypoxanthine phosphoribosyltransferase activity -> transferase activity\, transferring glycosyl groups
\|YOL075C\|	NO SYMBOL				CRZ1, DAL82, SIP4
YIL066C	RNR3	DNA replication -> cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ribonucleoside-diphosphate reductase activity -> oxidoreductase activity\, acting on CH2 groups	cytoplasm -> cytoplasm	RFX1, STB1
YKR092C	SRP40	nucleocytoplasmic transport -> transport	chaperone activity -> chaperone activity	nucleolus -> nucleus	CUP9, MET4, RAP1
YNR024W	NO SYMBOL
YOR294W	RRS1	ribosome biogenesis, rRNA processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism		nucleus -> nucleus	STB1
YNL299W	TRF5	sister chromatid cohesion -> cell proliferation	DNA-directed DNA polymerase activity -> transferase activity\, transferring phosphorus-containing groups	nucleus -> nucleus
YMR259C	NO SYMBOL				ARG80, GCR2, GTS1, HIR1, SRD1
YPL068C	NO SYMBOL				CBF1
YFR001W	LOC1	ribosomal large subunit biogenesis -> cell organization and biogenesis	mRNA binding -> RNA binding	nucleus -> nucleus	ARG80, GAL4, GTS1, HAP4, HIR1, LEU3, MSN2, MSN4, RCS1, RLM1, SWI4
\|YJL105W\|	SET4				ASH1, CIN5, FKH1, MTH1, PHD1, SKN7
YGR251W	NO SYMBOL				MSN4, PHD1, SKN7
YJR002W	MPP10	rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription		small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex, nucleolus, nucleus -> nucleus, ribonucleoprotein complex
\|YPR183W\|	DPM1	N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis -> lipid biosynthesis, biosynthesis, membrane lipid metabolism, protein metabolism, lipoprotein metabolism	transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity -> transferase activity\, transferring glycosyl groups	endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network -> cytoplasm, endomembrane system	SWI5
YGR245C	SDA1	actin cytoskeleton organization and biogenesis, start control point of mitotic cell cycle -> cell organization and biogenesis, cell proliferation		nucleus -> nucleus
\|YBR292C\|	NO SYMBOL				STE12, ZMS1
YGL016W	KAP122	protein-nucleus import, response to drug -> response to abiotic stimulus, protein metabolism, transport	protein carrier activity -> protein carrier activity	cytoplasm, nuclear pore -> cytoplasm, nucleus, integral to membrane, endomembrane system	MSN2
YPR010C	RPA135	transcription from Pol I promoter -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	DNA-directed RNA polymerase activity -> transferase activity\, transferring phosphorus-containing groups	DNA-directed RNA polymerase I complex -> nucleus	ROX1, SIG1
YGL079W	NO SYMBOL				PHO4, STP1
YOR310C	NOP58	rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription		small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	ABF1, SWI6
YBR069C	TAT1	amino acid transport -> transport	amino acid transporter activity -> carboxylic acid transporter activity	plasma membrane -> plasma membrane	CIN5, DAL81, PHD1, SWI4
YML125C	NO SYMBOL				MAL13, MSN4, NDD1, RME1, SWI5
\|YLL010C\|	PSR1	response to stress -> response to stress	protein phosphatase activity -> hydrolase activity\, acting on ester bonds	plasma membrane -> plasma membrane	CBF1
\|YDR279W\|	RNH202				GCR2, MBP1, RIM101, RLM1, SWI6, THI2
YMR229C	RRP5	rRNA processing, processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	RNA binding, snoRNA binding -> RNA binding	nucleolus, nucleolus organizer complex -> nucleus	FHL1, RAP1
YGR280C	PXR1	35S primary transcript processing, snRNA processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	RNA binding -> RNA binding	nucleolus -> nucleus
\|YKL145W\|	RPT1	ubiquitin-dependent protein catabolism -> catabolism, protein metabolism	ATPase activity, endopeptidase activity -> purine nucleotide binding, peptidase activity, hydrolase activity\, acting on acid anhydrides	proteasome regulatory particle (sensu Eukarya) -> cytoplasm, nucleus	REB1
YPL143W	RPL33A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, MET4, NDD1, PDR1, RAP1, RME1
YDR312W	SSF2	ribosomal large subunit assembly and maintenance, conjugation with cellular fusion -> cell organization and biogenesis, conjugation, sexual reproduction	rRNA binding -> RNA binding	nucleolus -> nucleus	ABF1, FKH2, INO4, RAP1
\|YKL120W\|	OAC1	oxaloacetate transport, sulfate transport -> transport	oxaloacetate carrier activity, sulfate porter activity -> electrochemical potential-driven transporter activity, anion transporter activity, organic cation transporter activity, carboxylic acid transporter activity	mitochondrial inner membrane -> cytoplasm, inner membrane	LEU3, MTH1
YLR249W	YEF3	translational elongation -> biosynthesis, protein metabolism	translation elongation factor activity -> translation factor activity\, nucleic acid binding	ribosome -> cytoplasm, ribonucleoprotein complex	INO2, INO4
Main:		cell organization and biogenesis (0.42)	RNA binding (0.30)	nucleus (0.65)	RAP1 (0.14)
Score:		0.34	0.09	0.54	0.093
P-value:		5.653E-04 (ribosome biogenesis and assembly)	2.381E-01 (snoRNA binding)	6.852E-05 (nucleolus)	3.677E-01 (MSN4)

ORF	SYMBOL	P	F	C	TF
YLR197W	SIK1	rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription		small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex, nucleus, nucleolus -> nucleus, ribonucleoprotein complex	DAL81, HAL9
YBR267W	NO SYMBOL
YPL043W	NOP4	rRNA processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	RNA binding -> RNA binding	nucleolus -> nucleus
YPL266W	DIM1	rRNA modification, 35S primary transcript processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription	rRNA (adenine-N6\,N6-)-dimethyltransferase activity -> transferase activity\, transferring one-carbon groups	nucleolus -> nucleus	ARG81, STP2
YGR272C	NO SYMBOL				REB1, STP2
YHR052W	CIC1	protein catabolism -> catabolism, protein metabolism	protein binding\, bridging -> protein binding	nucleolus, proteasome complex (sensu Eukarya) -> nucleus, cytoplasm	HAP4, MATa1
YNL132W	KRE33
YGR159C	NSR1	ribosomal small subunit assembly and maintenance, rRNA processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	single-stranded DNA binding, RNA binding -> DNA binding, RNA binding	nucleolus, nucleus -> nucleus
YML093W	UTP14	processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex
YGL169W	SUA5	cell growth and/or maintenance -> cell growth and/or maintenance			ABF1
YJL109C	UTP10	processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex
YDR101C	ARX1	ribosomal large subunit biogenesis -> cell growth and/or maintenance		nucleoplasm, cytoplasm -> nucleus, cytoplasm	IXR1, RFX1
YHR089C	GAR1	rRNA modification, 35S primary transcript processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription	RNA binding -> RNA binding	nucleolus, small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	CBF1, FZF1
YJL033W	HCA4	35S primary transcript processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ATP dependent RNA helicase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleolus -> nucleus	HIR2, USV1
YDR161W	NO SYMBOL
YDR496C	PUF6				RFX1
YNL209W	SSB2	protein biosynthesis -> biosynthesis, protein metabolism	chaperone activity, ATPase activity -> chaperone activity, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	polysome, cytoplasm -> cytoplasm, ribonucleoprotein complex	ABF1, RFX1
\|YIL122W\|	POG1	re-entry into mitotic cell cycle after pheromone arrest -> cell growth and/or maintenance, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus	specific RNA polymerase II transcription factor activity -> specific RNA polymerase II transcription factor activity	nucleus -> nucleus	ASH1, CIN5, NRG1, RLM1, SMP1, YAP6
YDR399W	HPT1	purine nucleotide biosynthesis -> biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	hypoxanthine phosphoribosyltransferase activity -> transferase activity\, transferring glycosyl groups
YMR131C	RRB1	ribosome biogenesis -> cell growth and/or maintenance		nucleolus -> nucleus	FZF1, MATa1, RGT1
YDR365C	NO SYMBOL				ABF1, MSS11, YJL206C
YGR145W	ENP2
YNL175C	NOP13		RNA binding -> RNA binding	nucleolus, nucleoplasm -> nucleus	INO2, INO4
YJR070C	NO SYMBOL				GAT3, YAP5
YJL050W	MTR4	35S primary transcript processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ATP dependent RNA helicase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleolus -> nucleus
YNL075W	IMP4	rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription	rRNA primary transcript binding -> RNA binding	small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	USV1
YNL308C	KRI1	ribosome biogenesis -> cell growth and/or maintenance		nucleolus -> nucleus
YGR162W	TIF4631	translational initiation -> biosynthesis, protein metabolism	translation initiation factor activity -> translation factor activity\, nucleic acid binding	ribosome -> cytoplasm, ribonucleoprotein complex	HSF1
YNR024W	NO SYMBOL
YJL138C	TIF2	translational initiation, regulation of translational initiation -> biosynthesis, protein metabolism	translation initiation factor activity, RNA helicase activity -> translation factor activity\, nucleic acid binding, RNA binding	ribosome, cytoplasm -> cytoplasm, ribonucleoprotein complex	PHD1
YMR239C	RNT1	35S primary transcript processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ribonuclease III activity -> hydrolase activity\, acting on ester bonds, RNA binding	nucleolus -> nucleus
YHR169W	DBP8	35S primary transcript processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ATP dependent RNA helicase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleolus -> nucleus
YGL171W	ROK1	35S primary transcript processing, mRNA splicing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ATP dependent RNA helicase activity, ATPase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleolus -> nucleus	RGT1
YMR259C	NO SYMBOL				ARG80, GCR2, GTS1, HIR1, SRD1
YFR001W	LOC1	ribosomal large subunit biogenesis -> cell growth and/or maintenance	mRNA binding -> RNA binding	nucleus -> nucleus	ARG80, GAL4, GTS1, HAP4, HIR1, LEU3, MSN2, MSN4, RCS1, RLM1, SWI4
YJR002W	MPP10	rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription		small nucleolar ribonucleoprotein complex, small nuclear ribonucleoprotein complex, nucleolus, nucleus -> nucleus, ribonucleoprotein complex
\|YPR183W\|	DPM1	N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis -> lipid biosynthesis, biosynthesis, membrane lipid metabolism, protein metabolism, lipoprotein metabolism	transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity -> transferase activity\, transferring glycosyl groups	endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network -> cytoplasm, endomembrane system	SWI5
YNR046W	NO SYMBOL				ABF1
YNL292W	PUS4	tRNA modification -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	pseudouridylate synthase activity -> carbon-oxygen lyase activity	mitochondrion, nucleus -> cytoplasm, nucleus	RCS1
YGR245C	SDA1	actin cytoskeleton organization and biogenesis, start control point of mitotic cell cycle -> cell growth and/or maintenance		nucleus -> nucleus
YMR049C	ERB1	rRNA processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism			RTG3
YNL112W	DBP2		RNA helicase activity -> RNA binding	bud neck -> site of polarized growth (sensu Fungi)
YCL059C	KRR1	ribosome biogenesis, rRNA processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism		nucleolus -> nucleus
\|YCR090C\|	NO SYMBOL
YOR272W	YTM1	chromosome organization and biogenesis (sensu Eukarya), ribosomal large subunit biogenesis -> cell growth and/or maintenance		nucleus, nucleolus -> nucleus	LEU3, PUT3, REB1
YOR359W	VTS1	protein-vacuolar targeting -> protein metabolism, cell growth and/or maintenance	intracellular transporter activity -> transporter activity	cytosol -> cytoplasm	RAP1
YCR016W	NO SYMBOL
YGR187C	HGH1				ABF1, HAP3, HIR1, RCS1, RTG1
YCR072C	NO SYMBOL				YFL044C
YGL078C	DBP3	ribosomal large subunit assembly and maintenance, 35S primary transcript processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ATP dependent RNA helicase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleolus -> nucleus
YKL056C	NO SYMBOL
YGL016W	KAP122	protein-nucleus import, response to drug -> response to abiotic stimulus, protein metabolism, cell growth and/or maintenance	protein carrier activity -> protein binding	cytoplasm, nuclear pore -> cytoplasm, nucleus, integral to membrane, endomembrane system	MSN2
YKL172W	EBP2	rRNA processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism		nucleolus -> nucleus	ABF1, FZF1, RFX1
YLR002C	NOC3	DNA replication initiation, rRNA processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription	chromatin binding, protein binding -> DNA binding, protein binding	nucleus, nucleolus -> nucleus	HIR1, IXR1, RCS1
YAL059W	ECM1	cell wall organization and biogenesis -> cell growth and/or maintenance			MOT3
YMR014W	BUD22	bud site selection -> cell growth and/or maintenance		nucleus -> nucleus	CUP9, HAL9, HIR2, LEU3, NDD1, RLM1, ROX1, SMP1, YAP6
YBR247C	ENP1	processing of 20S pre-rRNA, rRNA processing, cell growth and/or maintenance -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	nucleolus, nucleus -> nucleus
YBR104W	YMC2	transport -> cell growth and/or maintenance	transporter activity -> transporter activity	mitochondrial inner membrane -> cytoplasm, inner membrane	FKH1, FKH2
YMR310C	NO SYMBOL
YGL029W	CGR1	ribosome biogenesis, rRNA processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism		nucleolus -> nucleus
YJL148W	RPA34	transcription from Pol I promoter -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	DNA-directed RNA polymerase activity -> transferase activity\, transferring phosphorus-containing groups	DNA-directed RNA polymerase I complex, nucleus, nucleolus -> nucleus	AZF1, CHA4, CUP9, DAL81, DIG1, FZF1, GCR1, GCR2, GLN3, HAL9, HAP2, HAP3, HMS1, LEU3, MAC1, MBP1, MET31, MOT3, NDD1, PDR1, PHD1, REB1, RLM1, RME1, ROX1, RPH1, RTS2, SKN7, SWI5, YAP6, ZAP1
YPR010C	RPA135	transcription from Pol I promoter -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	DNA-directed RNA polymerase activity -> transferase activity\, transferring phosphorus-containing groups	DNA-directed RNA polymerase I complex -> nucleus	ROX1, SIG1
\|YDR184C\|	ATC1	response to stress, polar budding -> response to stress, asexual reproduction		nucleus -> nucleus	ARO80, GLN3, SIP4, SKO1
YPR144C	NOC4	ribosome biogenesis -> cell growth and/or maintenance		nucleus -> nucleus	HIR1
YOR310C	NOP58	rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription		small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	ABF1, SWI6
YOR381W	FRE3	iron-siderochrome transport, iron ion homeostasis -> cell growth and/or maintenance	ferric-chelate reductase activity -> oxidoreductase activity\, oxidizing metal ions	plasma membrane, integral to membrane -> plasma membrane, integral to membrane	CIN5, PDR1, YAP6
YHR128W	FUR1	pyrimidine salvage -> biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	uracil phosphoribosyltransferase activity -> transferase activity\, transferring glycosyl groups		CIN5
YML125C	NO SYMBOL				MAL13, MSN4, NDD1, RME1, SWI5
YNR053C	NOG2	mRNA splicing -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	GTPase activity -> purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleus, nucleolus, nucleoplasm -> nucleus, nucleoplasm	ABF1, AZF1
YOL022C	NO SYMBOL				MAC1, MOT3, RTS2
YMR290C	HAS1			nucleolus, nuclear membrane -> nucleus, endomembrane system	RAP1
YOR078W	BUD21	processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	ABF1, MSS11, SIG1, SKO1
YJL069C	UTP18				ABF1
\|YDR279W\|	RNH202				GCR2, MBP1, RIM101, RLM1, SWI6, THI2
YMR229C	RRP5	rRNA processing, processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	RNA binding, snoRNA binding -> RNA binding	nucleolus, nucleolus organizer complex -> nucleus	FHL1, RAP1
YGR280C	PXR1	35S primary transcript processing, snRNA processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	RNA binding -> RNA binding	nucleolus -> nucleus
YNL110C	NOP15	ribosomal large subunit biogenesis -> cell growth and/or maintenance		nucleus, nucleolus -> nucleus
\|YOR095C\|	RKI1	pentose-phosphate shunt -> coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism	ribose-5-phosphate isomerase activity -> intramolecular isomerase activity		FHL1, FKH2, RAP1
YLR276C	DBP9	ribosomal large subunit assembly and maintenance, 35S primary transcript processing -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ATP dependent RNA helicase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleolus -> nucleus	MATa1, RCS1, RTG3, SWI5
YKL014C	NO SYMBOL				ABF1
YLR222C	UTP13	processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	ABF1
YDR449C	UTP6	processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	FHL1, GAT3, HIR2, RAP1, RGM1, YAP5
YHR196W	UTP9	processing of 20S pre-rRNA -> cell growth and/or maintenance, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex, nucleolus, nucleus -> nucleus, ribonucleoprotein complex
YGL099W	LSG1	conjugation with cellular fusion, sporulation (sensu Saccharomyces), ribosome nucleus export -> conjugation, protein metabolism, cell growth and/or maintenance, sexual reproduction	GTPase activity -> purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	cytoplasm -> cytoplasm	PHO4
YLR249W	YEF3	translational elongation -> biosynthesis, protein metabolism	translation elongation factor activity -> translation factor activity\, nucleic acid binding	ribosome -> cytoplasm, ribonucleoprotein complex	INO2, INO4
Main:		cell growth and/or maintenance (0.77)	RNA binding (0.55)	nucleus (0.82)	ABF1 (0.21)
Score:		0.72	0.33	0.74	0.103
P-value:		4.632E-32 (ribosome biogenesis)	1.304E-08 (snoRNA binding)	1.478E-34 (nucleolus)	8.229E-01 (ABF1)

ORF	SYMBOL	P	F	C	TF
YDL232W	OST4	N-linked glycosylation -> biosynthesis, protein metabolism	dolichyl-diphospho-oligosaccharide-protein glycosyltransferase activity, protein binding\, bridging -> dolichyl-diphospho-oligosaccharide-protein glycosyltransferase activity, protein binding\, bridging	endoplasmic reticulum membrane -> cytoplasm, endomembrane system	REB1
YPL237W	SUI3	translational initiation -> biosynthesis, protein metabolism	translation initiation factor activity -> translation initiation factor activity	ribosome -> cytoplasm, ribonucleoprotein complex
YMR121C	RPL15B	protein biosynthesis -> biosynthesis, protein metabolism	RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	REB1
YNL111C	CYB5	sterol biosynthesis -> alcohol metabolism, biosynthesis, lipid metabolism	electron transporter activity -> electron transporter activity	microsome -> membrane fraction	ABF1, GCR2, GTS1, NRG1, REB1, ROX1
\|YMR186W\|	HSC82	protein folding, response to stress -> protein metabolism, response to stress	cation-transporting ATPase activity, chaperone activity -> cation-transporting ATPase activity, chaperone activity		BAS1, HAP2, HSF1, INO4, REB1, ROX1
YGR280C	PXR1	35S primary transcript processing, snRNA processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	RNA binding -> RNA binding	nucleolus -> nucleus
YOL006C	TOP1	negative regulation of recombination within rDNA repeats, DNA topological change, DNA strand elongation, chromatin assembly/disassembly, regulation of transcription from Pol II promoter, RNA elongation from Pol II promoter, mitotic chromosome condensation, nuclear migration -> cell organization and biogenesis, cell cycle, mitotic cell cycle, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	DNA topoisomerase type I activity -> DNA topoisomerase type I activity	nucleus -> nucleus	REB1
\|YMR002W\|	NO SYMBOL				NDD1, REB1, SWI6
Main:		biosynthesis (0.57)	RNA binding (0.29)	cytoplasm (0.50)	REB1 (1.00)
Score:		0.48	0.05	0.27	1.000
P-value:		6.902E-01 (protein biosynthesis)	4.182E-01 (binding)	1.018E+00 (ribosome)	5.891E-07 (REB1)

ORF	SYMBOL	P	F	C	TF
YNL201C	PSY2
YPL131W	RPL5	protein biosynthesis, ribosomal large subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism	RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, GAT3, RAP1
YNL024C	NO SYMBOL				GRF10(Pho2)
YBR295W	PCA1	copper ion homeostasis -> cell homeostasis	P-type ATPase activity -> purine nucleotide binding, primary active transporter activity, cation transporter activity, hydrolase activity\, acting on acid anhydrides	membrane -> membrane	GAL4, SMP1
YJR123W	RPS5	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	FHL1, GRF10(Pho2), HSF1, MSN4, YAP1
\|YBL022C\|	PIM1	proteolysis and peptidolysis, response to heat -> catabolism, response to abiotic stimulus, protein metabolism	ATP-dependent peptidase activity -> peptidase activity	mitochondrial matrix -> cytoplasm	RAP1
YLR146C	SPE4	pantothenate biosynthesis, spermine biosynthesis -> biosynthesis, amine metabolism, coenzymes and prosthetic group metabolism, amino acid and derivative metabolism, secondary metabolism	spermine synthase activity -> transferase activity\, transferring alkyl or aryl (other than methyl) groups
YPL090C	RPS6A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	FHL1, GAT3, INO4, RAP1, YAP5
YOL121C	RPS19A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	AZF1, FHL1, GCR1, GCR2, HAL9, MET31, MOT3, PDR1, RAP1, ROX1, RPH1, SMP1, YAP6, ZAP1
YLR061W	RPL22A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	BAS1, FHL1, HIR1, PDR1, RAP1, RCS1, RME1, ZAP1
YMR231W	PEP5	nonselective vesicle docking, homotypic vacuole fusion (non-autophagic), Golgi to endosome transport, late endosome to vacuole transport -> cell organization and biogenesis, transport, vesicle-mediated transport		vacuolar membrane (sensu Fungi) -> cytoplasm, vacuole	ARG81, DOT6, HAL9, HAP2, MCM1, YAP1
YLR003C	NO SYMBOL				ABF1
\|YNL101W\|	AVT4	neutral amino acid transport -> transport	neutral amino acid transporter activity -> carboxylic acid transporter activity	vacuole -> cytoplasm	HAP3, INO4, IXR1, PHD1, RAP1
YHL033C	RPL8A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1
YLR344W	RPL26A	protein biosynthesis -> biosynthesis, protein metabolism	RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, RAP1
YDL130W	RPP1B	protein biosynthesis, translational elongation -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, GAL4, RAP1, RFX1
YDR418W	RPL12B	protein biosynthesis, ribosomal large subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, GAT3, PDR1, RAP1, SMP1
YGR214W	RPS0A	protein biosynthesis, ribosomal small subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	FHL1, RAP1
YOL120C	RPL18A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, MAL13, RAP1, YAP5
YOR369C	RPS12	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	ARG80, FHL1, FKH2, LEU3, NDD1, PDR1, RME1, SMP1, YAP6
\|YHL038C\|	CBP2	RNA splicing -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	pre-mRNA splicing factor activity -> RNA binding	mitochondrion -> cytoplasm	RAP1
YOR096W	RPS7A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	FHL1, FKH2, RAP1
\|YJR138W\|	IML1				ABF1, DOT6, GCR2, MET31, REB1
\|YGR254W\|	ENO1	gluconeogenesis, glycolysis -> alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism	phosphopyruvate hydratase activity -> carbon-oxygen lyase activity	phosphopyruvate hydratase complex, cytoplasm -> cytoplasm	FKH2, MSN4, PDR1, SWI5, YAP5
YNL288W	CAF40	regulation of transcription from Pol II promoter -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism		CCR4-NOT complex -> nucleus	RAP1
YPR080W	TEF1	translational elongation -> biosynthesis, protein metabolism	translation elongation factor activity -> translation factor activity\, nucleic acid binding	ribosome -> cytoplasm, ribonucleoprotein complex	FHL1, PDR1, RAP1, YAP5
\|YKL180W\|	RPL17A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya), cytoplasm -> cytoplasm, ribonucleoprotein complex	FHL1, GAT3, RAP1
YOR213C	SAS5	chromatin silencing at telomere -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription	acetyltransferase activity -> transferase activity\, transferring acyl groups	nuclear chromosome\, telomeric region, nuclear chromatin -> chromosome, nuclear chromosome	GRF10(Pho2), SUM1
\|YBR117C\|	TKL2	pentose-phosphate shunt -> coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism	transketolase activity -> transferase activity\, transferring aldehyde or ketonic groups		FHL1, RAP1
YBR181C	RPS6B	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya), cytoplasm -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	FHL1, GAT3, MAL13, RAP1, RGM1
\|YGL196W\|	NO SYMBOL
YBR048W	RPS11B	protein biosynthesis, ribosomal small subunit assembly and maintenance, regulation of translational fidelity -> cell organization and biogenesis, biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	GAL4, HAP4, LEU3, MET31, MSN1
\|YKL072W\|	STB6				ARG81, ARO80, BAS1, CIN5, GCN4, GLN3, HAP3, MCM1, PHD1, REB1, RLM1, YJL206C, ZAP1
YBR118W	TEF2	translational elongation -> biosynthesis, protein metabolism	translation elongation factor activity -> translation factor activity\, nucleic acid binding	ribosome -> cytoplasm, ribonucleoprotein complex	FHL1, RAP1
YDL043C	PRP11	spliceosome assembly -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	RNA binding -> RNA binding	snRNP U2 -> nucleus, ribonucleoprotein complex	DAL81, STP1
\|YKL033W\|	NO SYMBOL				RPH1
YDL184C	RPL41A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, HAL9, HMS1, MAC1, MSS11, RAP1, RME1, SIG1
YGL076C	RPL7A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex
YDR449C	UTP6	processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	FHL1, GAT3, HIR2, RAP1, RGM1, YAP5
YNL096C	RPS7B	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	FHL1, GAT3, RAP1, SFP1
\|YMR013C\|	SEC59	protein-ER targeting, protein amino acid glycosylation -> cell organization and biogenesis, biosynthesis, protein modification, protein metabolism, transport	dolichol kinase activity -> transferase activity\, transferring phosphorus-containing groups	membrane -> membrane	FHL1, NDD1, RAP1, RLM1, RME1
Main:		biosynthesis (0.71)	structural constituent of ribosome (0.59)	cytoplasm (0.81)	RAP1 (0.62)
Score:		0.59	0.36	0.75	0.523
P-value:		5.747E-10 (protein biosynthesis)	1.212E-12 (structural constituent of ribosome)	5.334E-15 (cytosolic ribosome (sensu Eukarya))	9.623E-23 (FHL1)

ORF	SYMBOL	P	F	C	TF
YOR312C	RPL20B	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, FKH2, GAT3, RAP1
YBR295W	PCA1	copper ion homeostasis -> cell homeostasis	P-type ATPase activity -> adenyl nucleotide binding, P-P-bond-hydrolysis-driven transporter activity, cation transporter activity, hydrolase activity\, acting on acid anhydrides\, catalyzing transmembrane movement of substances, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides	membrane -> membrane	GAL4, SMP1
YBL087C	RPL23A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, IXR1, MSS11, PDR1, RAP1, SMP1, SOK2
\|YBR098W\|	MMS4	DNA repair, meiotic recombination -> cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	transcription co-activator activity, endonuclease activity -> protein binding, nuclease activity	nucleus -> nucleus
YJR145C	RPS4A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya), cytoplasm -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	ACE2, CIN5, FHL1, INO4, MTH1, RAP1, YAP6
YKR092C	SRP40	nucleocytoplasmic transport -> transport	chaperone activity -> chaperone activity	nucleolus -> nucleus	CUP9, MET4, RAP1
\|YMR224C\|	MRE11	DNA repair, double-strand break repair via nonhomologous end-joining, meiotic DNA double-strand break formation, meiotic DNA double-strand break processing, double-strand break repair via break-induced replication -> DNA metabolism, cell proliferation, catabolism	endonuclease activity, 3'-5' exonuclease activity, protein binding -> nuclease activity, protein binding	nucleus -> nucleus	RAP1
YLR344W	RPL26A	protein biosynthesis -> biosynthesis, protein metabolism	RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, RAP1
YOL120C	RPL18A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, MAL13, RAP1, YAP5
YOR369C	RPS12	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	ARG80, FHL1, FKH2, LEU3, NDD1, PDR1, RME1, SMP1, YAP6
YLR452C	SST2	signal transduction, adaptation to pheromone during conjugation with cellular fusion -> signal transduction, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus	GTPase activator activity -> GTPase activator activity	plasma membrane -> membrane	DIG1, FHL1, RAP1, STE12
\|YGL115W\|	SNF4	regulation of transcription from Pol II promoter, peroxisome organization and biogenesis -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	protein kinase activator activity -> protein kinase activator activity	plasma membrane, nucleus, cytoplasm -> membrane, nucleus, cytoplasm	BAS1, CAD1, MAC1, NRG1, PDR1, RAP1, SMP1, YAP5
\|YPR161C\|	SGV1	transcription, protein amino acid phosphorylation -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, phosphorus metabolism, protein metabolism	cyclin-dependent protein kinase activity -> phosphotransferase activity\, alcohol group as acceptor	nucleus -> nucleus	RAP1
YPR080W	TEF1	translational elongation -> biosynthesis, protein metabolism	translation elongation factor activity -> translation elongation factor activity	ribosome -> cytoplasm, ribonucleoprotein complex	FHL1, PDR1, RAP1, YAP5
\|YJL217W\|	NO SYMBOL				CIN5, MAC1, PHD1, SWI5, YAP6
YOR213C	SAS5	chromatin silencing at telomere -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription	acetyltransferase activity -> transferase activity\, transferring groups other than amino-acyl groups	nuclear chromosome\, telomeric region, nuclear chromatin -> chromosome, nuclear chromosome	GRF10(Pho2), SUM1
YDR450W	RPS18A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	FHL1, GAT3, HIR2, RAP1, RGM1, YAP5
YBR181C	RPS6B	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya), cytoplasm -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	FHL1, GAT3, MAL13, RAP1, RGM1
\|YGL196W\|	NO SYMBOL
YDR406W	PDR15	transport -> transport	ATP-binding cassette (ABC) transporter activity -> adenyl nucleotide binding, P-P-bond-hydrolysis-driven transporter activity, hydrolase activity\, acting on acid anhydrides\, catalyzing transmembrane movement of substances, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides	integral to membrane -> membrane
YNL311C	NO SYMBOL				GCN4, RAP1
YGL030W	RPL30	protein biosynthesis, rRNA processing, mRNA splicing, regulation of translation -> cell organization and biogenesis, biosynthesis, transcription, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya), cytoplasm -> cytoplasm, ribonucleoprotein complex	FHL1, GAT3, RAP1, SFP1
YKL006W	RPL14A	protein biosynthesis -> biosynthesis, protein metabolism	RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, GAT3, GRF10(Pho2), GTS1, RAP1
YDL184C	RPL41A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, HAL9, HMS1, MAC1, MSS11, RAP1, RME1, SIG1
YNL069C	RPL16B	protein biosynthesis -> biosynthesis, protein metabolism	RNA binding, structural constituent of ribosome -> RNA binding, structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, GAT3, PDR1, RAP1, RGM1, YAP5
\|YMR013C\|	SEC59	protein-ER targeting, protein amino acid glycosylation -> cell organization and biogenesis, biosynthesis, protein modification, protein metabolism, transport	dolichol kinase activity -> phosphotransferase activity\, alcohol group as acceptor	membrane -> membrane	FHL1, NDD1, RAP1, RLM1, RME1
YLR441C	RPS1A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	FHL1, GAT3, RAP1, YAP5
YLR249W	YEF3	translational elongation -> biosynthesis, protein metabolism	translation elongation factor activity -> translation elongation factor activity	ribosome -> cytoplasm, ribonucleoprotein complex	INO2, INO4
Main:		protein metabolism (0.68)	structural constituent of ribosome (0.52)	cytoplasm (0.64)	RAP1 (0.80)
Score:		0.50	0.27	0.47	0.717
P-value:		9.616E-08 (protein biosynthesis)	3.728E-08 (structural constituent of ribosome)	4.322E-10 (cytosolic ribosome (sensu Eukarya))	5.171E-18 (RAP1)

ORF	SYMBOL	P	F	C	TF
YLR028C	ADE16	'de novo' IMP biosynthesis, aerobic respiration, sporulation (sensu Saccharomyces) -> energy pathways, sporulation, biosynthesis, nucleotide metabolism	IMP cyclohydrolase activity, phosphoribosylaminoimidazole-carboxamide formyltransferase activity -> IMP cyclohydrolase activity, phosphoribosylaminoimidazole-carboxamide formyltransferase activity	cytosol -> cytoplasm
YLR201C	NO SYMBOL				ABF1
YJL079C	PRY1			nuclear membrane, endoplasmic reticulum -> nucleus, cytoplasm, endomembrane system	NDD1, PHD1, RAP1
YOL087C	NO SYMBOL				DAL82
\|YJL082W\|	IML2
YKL035W	UGP1	protein amino acid glycosylation, UDP-glucose metabolism -> biosynthesis, alcohol metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism, carbohydrate metabolism	UTP-glucose-1-phosphate uridylyltransferase activity -> UTP-glucose-1-phosphate uridylyltransferase activity
\|YMR291W\|	NO SYMBOL				RAP1
Main:		biosynthesis (1.00)	UTP-glucose-1-phosphate uridylyltransferase activity (0.50)	cytoplasm (1.00)	RAP1 (0.50)
Score:		1.00	0.00	1.00	0.167
P-value:		2.707E+00 (biosynthesis)	1.260E+00 (transferase activity)	4.849E+00 (cytoplasm)	2.885E-01 (RAP1)

ORF	SYMBOL	P	F	C	TF
\|YPL193W\|	RSA1	ribosomal large subunit assembly and maintenance -> cell organization and biogenesis		nucleoplasm -> nucleus
\|YBR213W\|	MET8	sulfate assimilation, siroheme biosynthesis -> sulfur metabolism, pigment metabolism, coenzymes and prosthetic group biosynthesis, coenzymes and prosthetic group metabolism, biosynthesis, heterocycle metabolism	siroheme synthase activity, ferrochelatase activity -> siroheme synthase activity, other lyase activity		IME4
YJL033W	HCA4	35S primary transcript processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ATP dependent RNA helicase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleolus -> nucleus	HIR2, USV1
YJR070C	NO SYMBOL				GAT3, YAP5
\|YDR297W\|	SUR2	sphingolipid metabolism, sphingolipid biosynthesis -> lipid metabolism, biosynthesis	sphingosine hydroxylase activity -> sphingosine hydroxylase activity	endoplasmic reticulum -> cytoplasm	CBF1, MTH1
\|YPR036W\|	VMA13	vacuolar acidification -> cell homeostasis, cell organization and biogenesis, transport	hydrogen-exporting ATPase activity -> purine nucleotide binding, cation transporter activity, primary active transporter activity, hydrolase activity\, acting on acid anhydrides	hydrogen-transporting ATPase V1 domain, vacuolar membrane (sensu Fungi) -> cytoplasm, vacuole
\|YPR183W\|	DPM1	N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis -> lipid biosynthesis, biosynthesis, membrane lipid metabolism, protein metabolism, lipoprotein metabolism	transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity -> transferase activity\, transferring glycosyl groups	endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network -> cytoplasm, endomembrane system	SWI5
YMR049C	ERB1	rRNA processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism			RTG3
YNL111C	CYB5	sterol biosynthesis -> alcohol metabolism, biosynthesis, lipid metabolism	electron transporter activity -> electron transporter activity	microsome -> membrane fraction	ABF1, GCR2, GTS1, NRG1, REB1, ROX1
YJL110C	GZF3	regulation of nitrogen utilization, nitrogen metabolism, negative regulation of transcription from Pol II promoter -> nitrogen metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription	specific RNA polymerase II transcription factor activity -> specific RNA polymerase II transcription factor activity	nucleus -> nucleus	ABF1, SIP4
\|YIL014W\|	MNT3	O-linked glycosylation -> biosynthesis, protein metabolism	alpha-1\,3-mannosyltransferase activity -> transferase activity\, transferring glycosyl groups		AZF1, GCR2, HIR1, RME1, ROX1
YGL029W	CGR1	ribosome biogenesis, rRNA processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism		nucleolus -> nucleus
YHR128W	FUR1	pyrimidine salvage -> biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	uracil phosphoribosyltransferase activity -> transferase activity\, transferring glycosyl groups		CIN5
YOL014W	NO SYMBOL
YBR048W	RPS11B	protein biosynthesis, ribosomal small subunit assembly and maintenance, regulation of translational fidelity -> cell organization and biogenesis, biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	GAL4, HAP4, LEU3, MET31, MSN1
YGL195W	GCN1	regulation of translational elongation -> biosynthesis, protein metabolism		cytosol, cytosolic ribosome (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	ABF1, GCR1, HAP3, MAC1, RLM1, ROX1
YNR054C	NO SYMBOL				HAP3, HAP5, IXR1, MCM1, RTG3, SFP1, SWI6
\|YBR294W\|	SUL1	sulfate transport -> transport	sulfate transporter activity -> anion transporter activity	plasma membrane -> plasma membrane	STB1
YLR222C	UTP13	processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	ABF1
YDR023W	SES1	amino acid activation -> biosynthesis, protein metabolism	serine-tRNA ligase activity -> ligase activity\, forming carbon-oxygen bonds, ligase activity\, forming phosphoric ester bonds	cytoplasm -> cytoplasm	GRF10(Pho2), MOT3
YGR001C	NO SYMBOL
YDL167C	NRP1
Main:		biosynthesis (0.53)	transferase activity\, transferring glycosyl groups (0.23)	cytoplasm (0.46)	ABF1 (0.25)
Score:		0.49	0.06	0.35	0.083
P-value:		1.118E-02 (ribosome biogenesis and assembly)	3.497E-01 (mannosyltransferase activity)	6.936E-01 (nucleolus)	5.474E-01 (ROX1)

ORF	SYMBOL	P	F	C	TF
YLR272C	YCS4	mitotic chromosome condensation -> cell proliferation, cell cycle		nuclear condensin complex -> chromosome, nucleus
YIL035C	CKA1	flocculation, protein amino acid phosphorylation, cell ion homeostasis, G1/S transition of mitotic cell cycle, G2/M transition of mitotic cell cycle, establishment of cell polarity (sensu Saccharomyces), regulation of transcription from Pol I promoter, regulation of transcription from Pol III promoter, response to DNA damage -> cell adhesion, phosphorus metabolism, cell homeostasis, cell proliferation, transcription, response to biotic stimulus, cell organization and biogenesis, protein metabolism	protein kinase CK2 activity -> protein kinase CK2 activity	protein kinase CK2 complex -> protein kinase CK2 complex	ABF1
YBL087C	RPL23A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, IXR1, MSS11, PDR1, RAP1, SMP1, SOK2
YLL032C	NO SYMBOL				FZF1, GCR2, SRD1
YHR046C	INM1	myo-inositol metabolism -> alcohol metabolism, carbohydrate metabolism	myo-inositol-1(or 4)-monophosphatase activity -> myo-inositol-1(or 4)-monophosphatase activity
\|YOR188W\|	MSB1	establishment of cell polarity (sensu Saccharomyces) -> cell organization and biogenesis		bud neck, bud tip -> site of polarized growth (sensu Fungi)
YPR195C	NO SYMBOL				FKH1, FKH2, HIR1, HIR2, INO4, RLM1
\|YPR185W\|	APG13	protein-vacuolar targeting, autophagy -> cell organization and biogenesis, autophagy, protein metabolism, transport	protein binding -> protein binding	extrinsic to membrane -> extrinsic to membrane	MET4, SWI6
YKL209C	STE6	peptide pheromone export -> transport	ATP-binding cassette (ABC) transporter activity -> ATP-binding cassette (ABC) transporter activity	integral to plasma membrane, shmoo tip -> integral to membrane, site of polarized growth (sensu Fungi), plasma membrane	MCM1, STE12
\|YOR111W\|	NO SYMBOL				UGA3
YNL111C	CYB5	sterol biosynthesis -> alcohol metabolism, biosynthesis, lipid metabolism	electron transporter activity -> electron transporter activity	microsome -> membrane fraction	ABF1, GCR2, GTS1, NRG1, REB1, ROX1
YGR001C	NO SYMBOL
YDR312W	SSF2	ribosomal large subunit assembly and maintenance, conjugation with cellular fusion -> cell organization and biogenesis, conjugation, sexual reproduction	rRNA binding -> rRNA binding	nucleolus -> nucleus	ABF1, FKH2, INO4, RAP1
YLR249W	YEF3	translational elongation -> biosynthesis, protein metabolism	translation elongation factor activity -> translation elongation factor activity	ribosome -> cytoplasm, ribonucleoprotein complex	INO2, INO4
Main:		cell organization and biogenesis (0.40)	translation elongation factor activity (0.12)	cytoplasm (0.22)	ABF1 INO4 (0.30)
Score:		0.36	0.00	0.08	0.178
P-value:		7.522E-01 (establishment of cell polarity (sensu Fungi))	3.763E+00 (transporter activity)	8.723E-01 (site of polarized growth (sensu Saccharomyces))	1.824E-01 (INO4)

ORF	SYMBOL	P	F	C	TF
YMR118C	NO SYMBOL				GTS1
YOL048C	NO SYMBOL				SKN7
YMR250W	GAD1	response to oxidative stress, glutamate catabolism -> oxygen and reactive oxygen species metabolism, amine metabolism, amino acid and derivative metabolism, organic acid metabolism, response to biotic stimulus, catabolism	glutamate decarboxylase activity -> carbon-carbon lyase activity	cytoplasm -> cytoplasm
YJL161W	NO SYMBOL				GRF10(Pho2), MAL13, NDD1
YJR019C	TES1	fatty acid oxidation -> lipid metabolism, organic acid metabolism	acyl-CoA thioesterase activity -> hydrolase activity\, acting on ester bonds	peroxisome -> cytoplasm	DAL82, MTH1
\|YOL055C\|	THI20	thiamin biosynthesis -> biosynthesis, vitamin metabolism	phosphomethylpyrimidine kinase activity -> transferase activity\, transferring phosphorus-containing groups
YMR148W	NO SYMBOL
YLR377C	FBP1	gluconeogenesis -> alcohol metabolism, carbohydrate metabolism, biosynthesis, energy pathways	fructose-bisphosphatase activity -> hydrolase activity\, acting on ester bonds	cytosol -> cytoplasm
\|YNL111C\|	CYB5	sterol biosynthesis -> alcohol metabolism, biosynthesis, lipid metabolism	electron transporter activity -> electron transporter activity	microsome -> membrane fraction	ABF1, GCR2, GTS1, NRG1, REB1, ROX1
YHR090C	YNG2	chromatin modification -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	enzyme activator activity -> enzyme activator activity	histone acetyltransferase complex, nucleus -> nucleus	ABF1, FKH1
\|YKR003W\|	OSH6	steroid biosynthesis -> biosynthesis, lipid metabolism	oxysterol binding -> oxysterol binding
\|YOR348C\|	PUT4	neutral amino acid transport -> transport	amino acid permease activity, neutral amino acid transporter activity -> carboxylic acid transporter activity, polyamine transporter activity, electrochemical potential-driven transporter activity	plasma membrane -> plasma membrane	SWI5
YOR152C	NO SYMBOL				HIR2
Main:		biosynthesis (0.50)	hydrolase activity\, acting on ester bonds (0.25)	cytoplasm (0.50)	ABF1 GTS1 (0.25)
Score:		0.32	0.04	0.20	0.071
P-value:		1.166E-01 (steroid biosynthesis)	1.227E+00 (hydrolase activity\, acting on ester bonds)	4.985E+00 (cytoplasm)	2.014E-01 (GTS1)

ORF	SYMBOL	P	F	C	TF
\|YLR197W\|	SIK1	rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription		small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex, nucleus, nucleolus -> nucleus, ribonucleoprotein complex	DAL81, HAL9
\|YHR027C\|	RPN1	ubiquitin-dependent protein catabolism -> catabolism, protein metabolism	endopeptidase activity, receptor activity -> peptidase activity, receptor activity	proteasome regulatory particle (sensu Eukarya), endoplasmic reticulum, cytoplasm -> cytoplasm, nucleus
YOL041C	NOP12	rRNA metabolism -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	RNA binding -> RNA binding	nucleolus -> nucleus	GTS1, MET31
YJL050W	MTR4	35S primary transcript processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	ATP dependent RNA helicase activity -> RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides	nucleolus -> nucleus
YNR046W	NO SYMBOL				ABF1
\|YNL292W\|	PUS4	tRNA modification -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	pseudouridylate synthase activity -> carbon-oxygen lyase activity	mitochondrion, nucleus -> cytoplasm, nucleus	RCS1
YNL112W	DBP2		RNA helicase activity -> RNA binding	bud neck -> site of polarized growth (sensu Fungi)
\|YGR187C\|	HGH1				ABF1, HAP3, HIR1, RCS1, RTG1
YDR527W	NO SYMBOL				ABF1, SKN7
\|YKL172W\|	EBP2	rRNA processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism		nucleolus -> nucleus	ABF1, FZF1, RFX1
YGR283C	NO SYMBOL				ACE2, RAP1, SMP1
YKL078W	DHR2	ribosome biogenesis -> cell organization and biogenesis	RNA helicase activity -> RNA binding	nucleolus -> nucleus	ABF1
YPR010C	RPA135	transcription from Pol I promoter -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	DNA-directed RNA polymerase activity -> transferase activity\, transferring phosphorus-containing groups	DNA-directed RNA polymerase I complex -> nucleus	ROX1, SIG1
YJL069C	UTP18				ABF1
YKL014C	NO SYMBOL				ABF1
YDR312W	SSF2	ribosomal large subunit assembly and maintenance, conjugation with cellular fusion -> cell organization and biogenesis, conjugation, sexual reproduction	rRNA binding -> RNA binding	nucleolus -> nucleus	ABF1, FKH2, INO4, RAP1
Main:		nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.67)	RNA binding (0.62)	nucleus (0.90)	ABF1 (0.62)
Score:		0.61	0.36	0.80	0.385
P-value:		1.075E-02 (ribosome biogenesis and assembly)	3.026E-03 (RNA helicase activity)	6.686E-06 (nucleolus)	5.587E-05 (ABF1)

ORF	SYMBOL	P	F	C	TF
YNL144C	NO SYMBOL				RAP1
YNL033W	NO SYMBOL				GAT1, MAL13
YNL019C	NO SYMBOL
\|YPR036W\|	VMA13	vacuolar acidification -> cell homeostasis, cell organization and biogenesis, transport	hydrogen-exporting ATPase activity -> hydrogen-exporting ATPase activity	hydrogen-transporting ATPase V1 domain, vacuolar membrane (sensu Fungi) -> hydrogen-transporting ATPase V1 domain, vacuolar membrane (sensu Fungi)
\|YGR287C\|	NO SYMBOL
YOL159C	NO SYMBOL				ARO80, CIN5, RLM1
YDR343C	HXT6	hexose transport -> transport	glucose transporter activity, fructose transporter activity, mannose transporter activity -> glucose transporter activity, fructose transporter activity, mannose transporter activity	plasma membrane -> plasma membrane	CIN5, INO4, NRG1, PHD1
YJR155W	AAD10	aldehyde metabolism -> aldehyde metabolism	benzyl alcohol dehydrogenase activity -> benzyl alcohol dehydrogenase activity
YLR152C	NO SYMBOL				GRF10(Pho2), PHO4, PUT3
\|YFR022W\|	NO SYMBOL
Main:		transport (0.67)	hydrogen-exporting ATPase activity (0.33)	vacuolar membrane (sensu Fungi) (0.50)	CIN5 (0.40)
Score:		0.33	0.00	0.00	0.100
P-value:		3.919E+00 (transport)	1.443E+00 (transporter activity)	2.912E+00 (membrane)	8.516E-01 (PUT3)

ORF	SYMBOL	P	F	C	TF
\|YNL122C\|	NO SYMBOL				ARO80
YKL077W	NO SYMBOL				CHA4, GCR1, HAP3, HIR1, IXR1, REB1, STP1
YMR321C	NO SYMBOL
YKL054C	DEF1	response to DNA damage, ubiquitin-dependent protein catabolism -> response to biotic stimulus, catabolism, protein metabolism		nucleus -> nucleus
YBR115C	LYS2	lysine biosynthesis\, aminoadipic pathway -> amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis	aminoadipate-semialdehyde dehydrogenase activity -> oxidoreductase activity\, acting on the aldehyde or oxo group of donors	cytoplasm -> cytoplasm	DAL81, GCN4
YKL152C	GPM1	gluconeogenesis, glycolysis -> alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism	phosphoglycerate mutase activity -> intramolecular transferase activity	cytosol -> cytoplasm	GCR1, GCR2, HSF1, RAP1
YNL102W	POL1	DNA replication\, priming, DNA replication initiation, lagging strand elongation, DNA repair synthesis -> DNA metabolism, cell proliferation	alpha DNA polymerase activity -> transferase activity\, transferring phosphorus-containing groups	alpha DNA polymerase\:primase complex -> nucleus	LEU3, MBP1
\|YOR348C\|	PUT4	neutral amino acid transport -> transport	amino acid permease activity, neutral amino acid transporter activity -> carboxylic acid transporter activity, polyamine transporter activity, electrochemical potential-driven transporter activity	plasma membrane -> plasma membrane	SWI5
YDR226W	ADK1	cell proliferation -> cell proliferation	adenylate kinase activity -> transferase activity\, transferring phosphorus-containing groups	cytoplasm, mitochondrial intermembrane space -> cytoplasm	PUT3
\|YNL246W\|	VPS75	protein-vacuolar targeting -> cell organization and biogenesis, protein metabolism, transport			AZF1, SIG1, STP2
Main:		biosynthesis (0.29)	transferase activity\, transferring phosphorus-containing groups (0.40)	cytoplasm (0.50)	GCR1 (0.25)
Score:		0.24	0.10	0.27	0.036
P-value:		2.148E+00 (catabolism)	1.072E+00 (transferase activity\, transferring phosphorus-containing groups)	5.453E+00 (nucleus)	9.644E-02 (GCR1)

ORF	SYMBOL	P	F	C	TF
YJR025C	BNA1	nicotinamide adenine dinucleotide biosynthesis -> coenzymes and prosthetic group metabolism, biosynthesis, water-soluble vitamin metabolism, vitamin metabolism	3-hydroxyanthranilate 3\,4-dioxygenase activity -> 3-hydroxyanthranilate 3\,4-dioxygenase activity	cytoplasm -> cytoplasm	GCN4, SUM1, SWI6
YDR399W	HPT1	purine nucleotide biosynthesis -> biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	hypoxanthine phosphoribosyltransferase activity -> hypoxanthine phosphoribosyltransferase activity
YBL092W	RPL32	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, RAP1
\|YOR095C\|	RKI1	pentose-phosphate shunt -> coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism	ribose-5-phosphate isomerase activity -> ribose-5-phosphate isomerase activity		FHL1, FKH2, RAP1
YGR001C	NO SYMBOL
YDR119W	NO SYMBOL				MSS11, SIG1, SKO1
Main:		biosynthesis (0.75)	3-hydroxyanthranilate 3\,4-dioxygenase activity (0.25)	cytoplasm (1.00)	RAP1 FHL1 (0.50)
Score:		0.67	0.00	1.00	0.167
P-value:		1.824E-02 (pyridine nucleotide metabolism)	2.099E+00 (enzyme activity)	4.698E+00 (cytoplasm)	1.060E-01 (FHL1)

ORF	SYMBOL	P	F	C	TF
YPR117W	NO SYMBOL				IME4, MBP1, SFP1
YGR094W	VAS1	valyl-tRNA aminoacylation -> biosynthesis, protein metabolism	valine-tRNA ligase activity -> valine-tRNA ligase activity	cytoplasm, mitochondrion -> cytoplasm	SIG1
YLR355C	ILV5	branched chain family amino acid biosynthesis, mitochondrial genome maintenance -> amine metabolism, cell organization and biogenesis, amino acid and derivative metabolism, organic acid metabolism, biosynthesis	ketol-acid reductoisomerase activity -> ketol-acid reductoisomerase activity	mitochondrion -> cytoplasm	GCN4, MET4
YBL092W	RPL32	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, RAP1
YOR095C	RKI1	pentose-phosphate shunt -> coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism	ribose-5-phosphate isomerase activity -> ribose-5-phosphate isomerase activity		FHL1, FKH2, RAP1
YGR001C	NO SYMBOL
Main:		biosynthesis (0.75)	structural constituent of ribosome (0.25)	cytoplasm (1.00)	RAP1 FHL1 (0.40)
Score:		0.50	0.00	1.00	0.100
P-value:		8.913E-01 (biosynthesis)	2.099E+00 (enzyme activity)	1.070E+00 (mitochondrion)	1.060E-01 (FHL1)

ORF	SYMBOL	P	F	C	TF
YNL189W	SRP1	nucleocytoplasmic transport -> transport	protein carrier activity -> protein carrier activity	nucleus, cytoplasm -> nucleus, cytoplasm	ABF1, MOT3
YPR117W	NO SYMBOL				IME4, MBP1, SFP1
YKR079C	NO SYMBOL				BAS1
YLR130C	ZRT2	low-affinity zinc ion transport -> transport	low-affinity zinc ion transporter activity -> low-affinity zinc ion transporter activity	plasma membrane -> plasma membrane	ZAP1
YMR130W	NO SYMBOL
\|YCR044C\|	PER1	manganese ion homeostasis, response to unfolded protein -> response to biotic stimulus, cell homeostasis		vacuolar membrane (sensu Fungi) -> cytoplasm, vacuole	YFL044C
\|YJR122W\|	CAF17				YAP1
Main:		transport (0.67)	low-affinity zinc ion transporter activity (0.50)	cytoplasm (0.67)	ABF1 (0.17)
Score:		0.33	0.00	0.33	0.000
P-value:		2.699E+00 (transport)	6.419E-01 (transporter activity)	3.145E+00 (membrane)	5.564E-01 (ZAP1)

ORF	SYMBOL	P	F	C	TF
YLR084C	RAX2	bud site selection -> establishment of cell polarity (sensu Saccharomyces), cytokinesis\, site selection		bud neck, bud scar, membrane -> site of polarized growth (sensu Fungi), cell wall, membrane	FKH2, MCM1, NDD1, SKN7, SWI4
\|YCL047C\|	NO SYMBOL				CIN5
YHR046C	INM1	myo-inositol metabolism -> myo-inositol metabolism	myo-inositol-1(or 4)-monophosphatase activity -> myo-inositol-1(or 4)-monophosphatase activity
YNL271C	BNI1	mitotic spindle orientation, response to osmotic stress, actin filament organization, bud growth, polar budding, Rho protein signal transduction, establishment of cell polarity (sensu Saccharomyces), mRNA localization\, intracellular -> spindle assembly, response to osmotic stress, actin filament organization, bud growth, polar budding, Rho protein signal transduction, establishment of cell polarity (sensu Saccharomyces), mRNA localization\, intracellular, mitosis	cytoskeletal regulatory protein binding -> cytoskeletal regulatory protein binding	polarisome, actin cap (sensu Saccharomyces) -> cell cortex, site of polarized growth (sensu Fungi), site of polarized growth (sensu Saccharomyces), cytoplasm	IME4, PHO4, SWI5
\|YGR147C\|	NAT2	N-terminal peptidyl-methionine acetylation -> N-terminal peptidyl-methionine acetylation	peptide alpha-N-acetyltransferase activity -> peptide alpha-N-acetyltransferase activity	cytoplasm -> cytoplasm	HIR1, REB1
YPR195C	NO SYMBOL				FKH1, FKH2, HIR1, HIR2, INO4, RLM1
YKL209C	STE6	peptide pheromone export -> peptide pheromone export	ATP-binding cassette (ABC) transporter activity -> ATP-binding cassette (ABC) transporter activity	integral to plasma membrane, shmoo tip -> site of polarized growth (sensu Fungi), membrane	MCM1, STE12
YGR001C	NO SYMBOL
Main:		establishment of cell polarity (sensu Saccharomyces) (0.40)	peptide alpha-N-acetyltransferase activity (0.25)	site of polarized growth (sensu Fungi) (0.75)	FKH2 MCM1 HIR1 (0.33)
Score:		0.10	0.00	0.67	0.200
P-value:		1.697E-01 (establishment of cell polarity (sensu Fungi))	2.351E+00 (hydrolase activity)	2.067E-02 (site of polarized growth (sensu Saccharomyces))	1.297E-01 (HIR1)

ORF	SYMBOL	P	F	C	TF
YPL140C	MKK2	protein amino acid phosphorylation, signal transduction -> phosphorus metabolism, signal transduction, protein metabolism	MAP kinase kinase activity -> MAP kinase kinase activity	intracellular -> intracellular	FKH1, FKH2
YKL054C	DEF1	response to DNA damage, ubiquitin-dependent protein catabolism -> response to biotic stimulus, catabolism, protein metabolism		nucleus -> intracellular
YBR115C	LYS2	lysine biosynthesis\, aminoadipic pathway -> amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis	aminoadipate-semialdehyde dehydrogenase activity -> aminoadipate-semialdehyde dehydrogenase activity	cytoplasm -> intracellular	DAL81, GCN4
YKL209C	STE6	peptide pheromone export -> transport	ATP-binding cassette (ABC) transporter activity -> ATP-binding cassette (ABC) transporter activity	integral to plasma membrane, shmoo tip -> integral to membrane, site of polarized growth (sensu Fungi), plasma membrane	MCM1, STE12
YGR060W	ERG25	ergosterol biosynthesis -> alcohol metabolism, biosynthesis, lipid metabolism	C-4 methyl sterol oxidase activity -> C-4 methyl sterol oxidase activity	endoplasmic reticulum membrane, plasma membrane -> intracellular, plasma membrane, endomembrane system	HSF1, MAL13, MET4, NDD1, SWI5
Main:		biosynthesis (0.40)	aminoadipate-semialdehyde dehydrogenase activity (0.25)	intracellular (0.80)	FKH2 (0.25)
Score:		0.20	0.00	0.70	0.000
P-value:		1.985E+00 (biosynthesis)	2.181E-01 (oxidoreductase activity)	3.563E-01 (plasma membrane)	5.638E-01 (MAL13)

ORF	SYMBOL	P	F	C	TF
YBR143C	SUP45	translational termination -> biosynthesis, protein metabolism	translation release factor activity\, codon specific -> translation release factor activity\, codon specific	cytosol -> cytoplasm	FZF1
YLR333C	RPS25B	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic small ribosomal subunit (sensu Eukarya) -> eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex	FHL1, RAP1
\|YPR183W\|	DPM1	N-linked glycosylation, O-linked glycosylation, GPI anchor biosynthesis -> lipid biosynthesis, biosynthesis, membrane lipid metabolism, protein metabolism, lipoprotein metabolism	transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity -> transferase activity\, transferring glycosyl groups, dolichyl-phosphate beta-D-mannosyltransferase activity	endoplasmic reticulum, nuclear envelope-endoplasmic reticulum network -> cytoplasm, endomembrane system	SWI5
YHR007C	ERG11	ergosterol biosynthesis -> alcohol metabolism, biosynthesis, lipid metabolism	sterol 14-demethylase activity -> sterol 14-demethylase activity	endoplasmic reticulum -> cytoplasm
YGR233C	PHO81	phosphate metabolism -> phosphorus metabolism	cyclin-dependent protein kinase inhibitor activity -> cyclin-dependent protein kinase inhibitor activity		CAD1, CIN5, HIR2, INO4, PHD1
YDR217C	RAD9	DNA repair, regulation of cell cycle, nucleotide-excision repair, DNA damage checkpoint, positive regulation of transcription from Pol II promoter -> cell proliferation, cell cycle, response to biotic stimulus, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	protein binding -> protein binding	nucleus -> nucleus
YPL032C	SVL3	endocytosis -> transport			FKH1, HSF1
\|YJR122W\|	CAF17				YAP1
YBR031W	RPL4A	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex
YDL167C	NRP1
\|YGL162W\|	SUT1	regulation of transcription from Pol II promoter, sterol transport -> transport, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	specific RNA polymerase II transcription factor activity -> specific RNA polymerase II transcription factor activity	nucleus -> nucleus
Main:		biosynthesis (0.56)	structural constituent of ribosome (0.25)	cytoplasm (0.71)	FZF1 (0.17)
Score:		0.33	0.04	0.52	0.000
P-value:		5.164E-01 (protein biosynthesis)	8.253E-01 (structural constituent of ribosome)	9.328E-01 (cytosolic ribosome (sensu Eukarya))	1.000E+00

ORF	SYMBOL	P	F	C	TF
YGR195W	SKI6	mRNA catabolism, 35S primary transcript processing -> catabolism, cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	3'-5' exoribonuclease activity -> hydrolase activity\, acting on ester bonds, RNA binding	nuclear exosome (RNase complex), cytoplasmic exosome (RNase complex) -> exosome (RNase complex), cytoplasm, nucleus	HSF1
YJL109C	UTP10	processing of 20S pre-rRNA -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	snoRNA binding -> RNA binding	small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex
YNL111C	CYB5	sterol biosynthesis -> alcohol metabolism, biosynthesis, lipid metabolism	electron transporter activity -> electron transporter activity	microsome -> membrane fraction	ABF1, GCR2, GTS1, NRG1, REB1, ROX1
YPR080W	TEF1	translational elongation -> biosynthesis, protein metabolism	translation elongation factor activity -> translation factor activity\, nucleic acid binding	ribosome -> cytoplasm, ribonucleoprotein complex	FHL1, PDR1, RAP1, YAP5
YDR091C	RLI1		ATP-binding cassette (ABC) transporter activity -> purine nucleotide binding, primary active transporter activity, hydrolase activity\, acting on acid anhydrides
YGR001C	NO SYMBOL
YDR472W	TRS31	ER to Golgi transport -> transport, vesicle-mediated transport		TRAPP -> cytoplasm	GCR1, IXR1, RFX1
\|YLR342W\|	FKS1	beta-1\,3 glucan biosynthesis, cell wall organization and biogenesis -> biosynthesis, cell organization and biogenesis, carbohydrate metabolism	1\,3-beta-glucan synthase activity -> transferase activity\, transferring glycosyl groups	actin cap (sensu Saccharomyces), 1\,3-beta-glucan synthase complex -> cell cortex, plasma membrane, cytoplasm	MBP1, RLM1, STB1, SWI4
Main:		cell organization and biogenesis (0.50)	RNA binding (0.33)	cytoplasm (0.67)	GCR2 (0.20)
Score:		0.40	0.07	0.53	0.000
P-value:		3.789E-01 (rRNA processing)	8.847E-01 (RNA binding)	1.459E+00 (ribonucleoprotein complex)	1.000E+00

ORF	SYMBOL	P	F	C	TF
\|YOL091W\|	SPO21	spore wall assembly (sensu Saccharomyces), meiosis -> cell proliferation, sporulation	structural molecule activity -> structural molecule activity	spindle pole body -> cytoplasm	HAP5, SUM1
\|YNL122C\|	NO SYMBOL				ARO80
\|YFR009W\|	GCN20	regulation of translational elongation -> biosynthesis, protein metabolism		cytosol, cytosolic ribosome (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex
YJR025C	BNA1	nicotinamide adenine dinucleotide biosynthesis -> coenzymes and prosthetic group metabolism, biosynthesis, water-soluble vitamin metabolism, vitamin metabolism	3-hydroxyanthranilate 3\,4-dioxygenase activity -> 3-hydroxyanthranilate 3\,4-dioxygenase activity	cytoplasm -> cytoplasm	GCN4, SUM1, SWI6
YLR022C	NO SYMBOL				USV1
YDR399W	HPT1	purine nucleotide biosynthesis -> biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	hypoxanthine phosphoribosyltransferase activity -> hypoxanthine phosphoribosyltransferase activity
YPR117W	NO SYMBOL				IME4, MBP1, SFP1
YLR175W	CBF5	rRNA modification, 35S primary transcript processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription	pseudouridylate synthase activity -> pseudouridylate synthase activity	small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	AZF1, HAL9
YGR094W	VAS1	valyl-tRNA aminoacylation -> biosynthesis, protein metabolism	valine-tRNA ligase activity -> valine-tRNA ligase activity	cytoplasm, mitochondrion -> cytoplasm	SIG1
YLR355C	ILV5	branched chain family amino acid biosynthesis, mitochondrial genome maintenance -> amine metabolism, cell organization and biogenesis, amino acid and derivative metabolism, organic acid metabolism, biosynthesis	ketol-acid reductoisomerase activity -> ketol-acid reductoisomerase activity	mitochondrion -> cytoplasm	GCN4, MET4
\|YOR295W\|	UAF30	transcription from Pol I promoter -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	RNA polymerase I transcription factor activity, ribosomal DNA (rDNA) binding -> RNA polymerase I transcription factor activity, ribosomal DNA (rDNA) binding	RNA polymerase I upstream activating factor complex -> nucleus
YBL092W	RPL32	protein biosynthesis -> biosynthesis, protein metabolism	structural molecule activity -> structural molecule activity	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, RAP1
YOR095C	RKI1	pentose-phosphate shunt -> coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism	ribose-5-phosphate isomerase activity -> ribose-5-phosphate isomerase activity		FHL1, FKH2, RAP1
YGR001C	NO SYMBOL
YDR119W	NO SYMBOL				MSS11, SIG1, SKO1
Main:		biosynthesis (0.60)	structural molecule activity (0.22)	cytoplasm (0.75)	SUM1 RAP1 FHL1 SIG1 GCN4 (0.18)
Score:		0.44	0.03	0.64	0.073
P-value:		2.312E-01 (pyridine nucleotide metabolism)	1.712E+00 (oxidoreductase activity)	1.398E+00 (nucleolus)	2.613E-01 (SIG1)

ORF	SYMBOL	P	F	C	TF
YMR277W	FCP1	protein amino acid dephosphorylation, transcription -> phosphorus metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism	protein phosphatase activity, phosphoric monoester hydrolase activity -> hydrolase activity\, acting on ester bonds	nucleus -> nucleus
\|YNL042W\|	BOP3				DAL82
YJR070C	NO SYMBOL				GAT3, YAP5
\|YPL128C\|	TBF1	loss of chromatin silencing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription	DNA binding, transcription factor activity -> DNA binding	nuclear chromosome\, telomeric region, nuclear chromosome, nucleus -> chromosome, nucleus
YMR259C	NO SYMBOL				ARG80, GCR2, GTS1, HIR1, SRD1
\|YMR042W\|	ARG80	positive regulation of transcription from Pol II promoter, arginine metabolism -> amine metabolism, nitrogen metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, amino acid and derivative metabolism, organic acid metabolism	DNA binding, specific RNA polymerase II transcription factor activity -> DNA binding, specific RNA polymerase II transcription factor activity	nucleus -> nucleus	RME1
YGR240C	PFK1	glycolysis -> carbohydrate metabolism, alcohol metabolism, carbohydrate catabolism, energy pathways, catabolism	6-phosphofructokinase activity -> carbohydrate kinase activity, transferase activity\, transferring phosphorus-containing groups	6-phosphofructokinase complex, cytoplasm -> cytoplasm	GCR1, HIR1, HIR2
\|YLR328W\|	NMA1	nicotinamide adenine dinucleotide metabolism -> coenzymes and prosthetic group metabolism, vitamin metabolism	nicotinamide-nucleotide adenylyltransferase activity -> transferase activity\, transferring phosphorus-containing groups		CIN5, MSN1, ROX1
YHR128W	FUR1	pyrimidine salvage -> biosynthesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	uracil phosphoribosyltransferase activity -> transferase activity\, transferring glycosyl groups		CIN5
YNL102W	POL1	DNA replication\, priming, DNA replication initiation, lagging strand elongation, DNA repair synthesis -> DNA metabolism, cell proliferation	alpha DNA polymerase activity -> transferase activity\, transferring phosphorus-containing groups	alpha DNA polymerase\:primase complex -> nucleus	LEU3, MBP1
YMR290C	HAS1			nucleolus, nuclear membrane -> nucleus, endomembrane system	RAP1
YPL032C	SVL3	endocytosis -> transport			FKH1, HSF1
YBL092W	RPL32	protein biosynthesis -> biosynthesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	FHL1, RAP1
Main:		nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.44)	transferase activity\, transferring phosphorus-containing groups (0.38)	nucleus (0.71)	RAP1 CIN5 HIR1 (0.18)
Score:		0.22	0.14	0.52	0.055
P-value:		2.612E+00 (regulation of transcription\, DNA-dependent)	1.868E-01 (nucleotidyltransferase activity)	3.063E+00 (cytosol)	4.268E-01 (HIR1)

ORF	SYMBOL	P	F	C	TF
YPR074C	TKL1	pentose-phosphate shunt -> coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism	transketolase activity -> transketolase activity	cytoplasm -> cytoplasm	REB1
YKL018W	SWD2	histone methylation -> cell organization and biogenesis, protein metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	histone-lysine N-methyltransferase activity -> histone-lysine N-methyltransferase activity	nucleus -> nucleus
YMR259C	NO SYMBOL				ARG80, GCR2, GTS1, HIR1, SRD1
YGR240C	PFK1	glycolysis -> carbohydrate metabolism, alcohol metabolism, carbohydrate catabolism, energy pathways, catabolism	6-phosphofructokinase activity -> 6-phosphofructokinase activity	6-phosphofructokinase complex, cytoplasm -> cytoplasm	GCR1, HIR1, HIR2
\|YKL109W\|	HAP4	transcription, regulation of carbohydrate metabolism -> nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, carbohydrate metabolism, energy pathways, regulation of metabolism	transcriptional activator activity -> transcriptional activator activity	CCAAT-binding factor complex -> nucleus	ASH1, PHD1, SKN7, SWI4, YAP6
YOR063W	RPL3	protein biosynthesis, ribosomal large subunit assembly and maintenance -> biosynthesis, cell organization and biogenesis, protein metabolism	structural constituent of ribosome -> structural constituent of ribosome	cytosolic large ribosomal subunit (sensu Eukarya) -> cytoplasm, ribonucleoprotein complex	GRF10(Pho2)
\|YJR129C\|	NO SYMBOL				DOT6, SIP4
YPL032C	SVL3	endocytosis -> transport			FKH1, HSF1
YGR280C	PXR1	35S primary transcript processing, snRNA processing -> cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism	RNA binding -> RNA binding	nucleolus -> nucleus
Main:		cell organization and biogenesis (0.43)	6-phosphofructokinase activity (0.17)	cytoplasm (0.50)	HIR1 (0.29)
Score:		0.38	0.00	0.40	0.048
P-value:		9.305E-02 (glucose catabolism)	6.615E-01 (transferase activity)	1.871E+00 (cytosol)	1.855E-01 (HIR1)

ORF	SYMBOL	P	F	C	TF
\|YOR006C\|	NO SYMBOL
YGR200C	ELP2	regulation of transcription from Pol II promoter -> regulation of transcription, transcription\, DNA-dependent	Pol II transcription elongation factor activity -> Pol II transcription elongation factor activity	transcription elongation factor complex -> nucleus	YJL206C
YHR089C	GAR1	rRNA modification, 35S primary transcript processing -> RNA processing, ribosome biogenesis and assembly, rRNA metabolism, transcription\, DNA-dependent	RNA binding -> RNA binding	nucleolus, small nucleolar ribonucleoprotein complex -> nucleus, ribonucleoprotein complex	CBF1, FZF1
YML018C	NO SYMBOL
YMR259C	NO SYMBOL				ARG80, GCR2, GTS1, HIR1, SRD1
\|YMR042W\|	ARG80	positive regulation of transcription from Pol II promoter, arginine metabolism -> amino acid metabolism, regulation of transcription, urea cycle intermediate metabolism, transcription\, DNA-dependent	DNA binding, specific RNA polymerase II transcription factor activity -> DNA binding, specific RNA polymerase II transcription factor activity	nucleus -> nucleus	RME1
YGR233C	PHO81	phosphate metabolism -> phosphate metabolism	cyclin-dependent protein kinase inhibitor activity -> cyclin-dependent protein kinase inhibitor activity		CAD1, CIN5, HIR2, INO4, PHD1
Main:		transcription\, DNA-dependent (0.75)	specific RNA polymerase II transcription factor activity (0.25)	nucleus (1.00)	GCR2 (0.20)
Score:		0.50	0.00	1.00	0.000
P-value:		3.006E-01 (regulation of transcription from Pol II promoter)	5.709E-01 (transcription regulator activity)	2.273E+00 (nucleus)	1.000E+00

ORF	SYMBOL	P	F	C	TF
\|YOL041C\|	NOP12	rRNA metabolism -> RNA metabolism	RNA binding -> RNA binding	nucleolus -> nucleus	GTS1, MET31
YNL292W	PUS4	tRNA modification -> RNA metabolism	pseudouridylate synthase activity -> carbon-oxygen lyase activity	mitochondrion, nucleus -> cytoplasm, nucleus	RCS1
YGR187C	HGH1				ABF1, HAP3, HIR1, RCS1, RTG1
YGR283C	NO SYMBOL				ACE2, RAP1, SMP1
YKL078W	DHR2	ribosome biogenesis -> cytoplasm organization and biogenesis	RNA helicase activity -> RNA binding	nucleolus -> nucleus	ABF1
YJL069C	UTP18				ABF1
YKL014C	NO SYMBOL				ABF1
YDR312W	SSF2	ribosomal large subunit assembly and maintenance, conjugation with cellular fusion -> cytoplasm organization and biogenesis, conjugation with cellular fusion	rRNA binding -> RNA binding	nucleolus -> nucleus	ABF1, FKH2, INO4, RAP1
Main:		cytoplasm organization and biogenesis (0.50)	RNA binding (0.75)	nucleus (1.00)	ABF1 (0.62)
Score:		0.33	0.50	1.00	0.429
P-value:		5.379E-01 (ribosome biogenesis and assembly)	9.691E-02 (RNA binding)	1.729E-02 (nucleolus)	7.462E-04 (ABF1)

ORF	SYMBOL	P	F	C	TF
YJR016C	ILV3	branched chain family amino acid biosynthesis -> amino acid biosynthesis, branched chain family amino acid metabolism	dihydroxy-acid dehydratase activity -> hydro-lyase activity	mitochondrion -> cytoplasm
YLR355C	ILV5	branched chain family amino acid biosynthesis, mitochondrial genome maintenance -> amino acid biosynthesis, mitochondrion organization and biogenesis, branched chain family amino acid metabolism	ketol-acid reductoisomerase activity -> oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor	mitochondrion -> cytoplasm	GCN4, MET4
YGL009C	LEU1	leucine biosynthesis -> amino acid biosynthesis, branched chain family amino acid metabolism	3-isopropylmalate dehydratase activity -> hydro-lyase activity	cytosol -> cytoplasm	LEU3
YDR158W	HOM2	homoserine biosynthesis, threonine metabolism, methionine metabolism -> amino acid biosynthesis, aspartate family amino acid metabolism, homoserine metabolism, serine family amino acid metabolism, sulfur amino acid metabolism	aspartate-semialdehyde dehydrogenase activity -> oxidoreductase activity\, acting on the aldehyde or oxo group of donors\, NAD or NADP as acceptor		ACE2, HSF1, NDD1, REB1, SKN7, SWI5
YOR108W	LEU9	leucine biosynthesis -> amino acid biosynthesis, branched chain family amino acid metabolism	2-isopropylmalate synthase activity -> oxo-acid-lyase activity	mitochondrion -> cytoplasm	AZF1, GCN4, LEU3
Main:		amino acid biosynthesis (1.00)	hydro-lyase activity (0.40)	cytoplasm (1.00)	LEU3 GCN4 (0.50)
Score:		1.00	0.10	1.00	0.333
P-value:		1.808E-08 (branched chain family amino acid biosynthesis)	2.482E-03 (lyase activity)	1.074E-01 (mitochondrion)	1.038E-02 (LEU3)