LYS14(1) AND mRRPE(1) AND PAC(1) => SimExpr(YGR280C) OR SimExpr(other) : 6 2

    EXPR: (0.190) LYS14 (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.003)

ORFSYMBOLPFCTF
YJR070CNO SYMBOLGAT3, YAP5
YHR052WCIC1protein catabolism ->
macromolecule catabolism, protein metabolism
protein binding\, bridging ->
protein binding\, bridging
nucleolus, proteasome complex (sensu Eukarya) ->
nucleus, cytoplasm
HAP4, MATa1
YGL099WLSG1conjugation with cellular fusion, sporulation (sensu Saccharomyces), ribosome nucleus export ->
conjugation with cellular fusion, sporulation (sensu Fungi), cytoplasm organization and biogenesis, intracellular transport, protein metabolism, protein transport
GTPase activity ->
purine nucleotide binding, hydrolase activity\, acting on acid anhydrides
cytoplasm ->
cytoplasm
PHO4
YGR280CPXR135S primary transcript processing, snRNA processing ->
cytoplasm organization and biogenesis, RNA metabolism, transcription
RNA binding ->
RNA binding
nucleolus ->
nucleus
YML093WUTP14processing of 20S pre-rRNA ->
cytoplasm organization and biogenesis, RNA metabolism, transcription
snoRNA binding ->
RNA binding
small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
YNL110CNOP15ribosomal large subunit biogenesis ->
cytoplasm organization and biogenesis
nucleus, nucleolus ->
nucleus
|YMR290C|HAS1nucleolus, nuclear membrane ->
nucleus, endomembrane system
RAP1
|YMR259C|NO SYMBOLARG80, GCR2, GTS1, HIR1, SRD1
Main:cytoplasm organization and biogenesis (0.80)RNA binding (0.50)nucleus (0.83)GCR2 (0.20)
Score:0.700.170.730.000
P-value:3.295E-03 (ribosome biogenesis)6.494E-01 (RNA binding)3.761E-05 (nucleolus)9.470E-01 (MATa1)

CSRE(1) AND ALPHA1(1) AND STRE(1) => SimExpr(YKL085W) OR SimExpr(other) : 5 1

    EXPR: (0.199) STRE (P < 0.005) CSRE (P < 0.000) ALPHA1 (P < 0.000)

ORFSYMBOLPFCTF
|YGL062W|PYC1NADPH regeneration, gluconeogenesis ->
coenzymes and prosthetic group metabolism, alcohol metabolism, carbohydrate metabolism, vitamin metabolism, biosynthesis, energy pathways
pyruvate carboxylase activity ->
pyruvate carboxylase activity
cytosol ->
cytoplasm
DIG1, GCR1, STE12
YKL085WMDH1tricarboxylic acid cycle, malate metabolism ->
carbohydrate metabolism, organic acid metabolism, energy pathways
L-malate dehydrogenase activity ->
L-malate dehydrogenase activity
mitochondrial matrix ->
cytoplasm
IME4, MTH1, RTG1, YJL206C
YIL052CRPL34Bprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
RME1
YNL098CRAS2pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction ->
cell organization and biogenesis, sporulation, signal transduction
RAS small monomeric GTPase activity ->
RAS small monomeric GTPase activity
plasma membrane ->
plasma membrane
ACE2, SKN7
YMR291WNO SYMBOLRAP1
YDR276CPMP3cation transport ->
transport
plasma membrane ->
plasma membrane
GAT1
Main:energy pathways (0.40)pyruvate carboxylase activity (0.25)cytoplasm (0.60)RTG1 (0.17)
Score:0.200.000.400.000
P-value:8.572E-02 (main pathways of carbohydrate metabolism)2.077E+00 (enzyme activity)4.197E-01 (plasma membrane)5.170E-01 (GAT1)

RAP1(1) AND MCM1'(1) => SimExpr(YOL120C) OR SimExpr(other) : 18 2

    EXPR: (0.127) MCM1' (P < 0.000) RAP1 (P < 0.000)

ORFSYMBOLPFCTF
|YPL180W|BIT89glycerol metabolism ->
alcohol metabolism, glycerol ether metabolism, lipid metabolism
REB1, RGT1, SIG1
YMR230WRPS10Bprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
cytosol, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome
FHL1, RAP1
YKL006WRPL14Aprotein biosynthesis ->
biosynthesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, GAT3, GRF10(Pho2), GTS1, RAP1
YIL018WRPL2Bprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, GAT3, PDR1, RAP1, RGM1, SWI5, YAP5
YGR254WENO1gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism
phosphopyruvate hydratase activity ->
phosphopyruvate hydratase activity
phosphopyruvate hydratase complex, cytoplasm ->
cytosol, cytoplasm
FKH2, MSN4, PDR1, SWI5, YAP5
|YLR452C|SST2signal transduction, adaptation to pheromone during conjugation with cellular fusion ->
signal transduction, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus
GTPase activator activity ->
GTPase activator activity
plasma membrane ->
plasma membrane
DIG1, FHL1, RAP1, STE12
YNL069CRPL16Bprotein biosynthesis ->
biosynthesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, GAT3, PDR1, RAP1, RGM1, YAP5
YDL130WRPP1Bprotein biosynthesis, translational elongation ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, GAL4, RAP1, RFX1
YPL090CRPS6Aprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
cytosol, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome
FHL1, GAT3, INO4, RAP1, YAP5
YJR139CHOM6homoserine biosynthesis, methionine metabolism, threonine metabolism ->
amine metabolism, sulfur metabolism, biosynthesis, amino acid and derivative metabolism, organic acid metabolism
homoserine dehydrogenase activity ->
homoserine dehydrogenase activity
HMS1, RAP1
YMR142CRPL13Bprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, GAT3, RAP1, RGM1, YAP5
YGL147CRPL9Aprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, MBP1, RAP1, SWI4
YGL030WRPL30protein biosynthesis, rRNA processing, mRNA splicing, regulation of translation ->
cell organization and biogenesis, biosynthesis, transcription, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya), cytoplasm ->
cytosol, cytoplasm, ribosome
FHL1, GAT3, RAP1, SFP1
YOL120CRPL18Aprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, MAL13, RAP1, YAP5
YML073CRPL6Aprotein biosynthesis, ribosomal large subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, GAT3, RAP1, YAP5
YGR214WRPS0Aprotein biosynthesis, ribosomal small subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
cytosol, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome
FHL1, RAP1
YDR450WRPS18Aprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
cytosol, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome
FHL1, GAT3, HIR2, RAP1, RGM1, YAP5
YKL152CGPM1gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism
phosphoglycerate mutase activity ->
phosphoglycerate mutase activity
cytosol ->
cytosol
GCR1, GCR2, HSF1, RAP1
YLR344WRPL26Aprotein biosynthesis ->
biosynthesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, RAP1
YGR085CRPL11Bprotein biosynthesis, ribosomal large subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, MIG1
Main:biosynthesis (0.90)structural constituent of ribosome (0.79)cytosol (0.94)RAP1 (0.85)
Score:0.820.610.890.832
P-value:1.901E-09 (protein biosynthesis)2.406E-14 (structural constituent of ribosome)3.100E-16 (cytosolic ribosome (sensu Eukarya))1.225E-20 (FHL1)

RAP1(1) AND mRRPE(1) => SimExpr(YOL120C) OR SimExpr(other) : 7 3

    EXPR: (0.160) mRRPE (P < 0.000) RAP1 (P < 0.108)

ORFSYMBOLPFCTF
YMR116CASC1cytoplasm ->
cytoplasm
FHL1, RAP1
YLR249WYEF3translational elongation ->
macromolecule biosynthesis, protein metabolism
translation elongation factor activity ->
translation elongation factor activity
ribosome ->
cytoplasm, ribonucleoprotein complex
INO2, INO4
YDL130WRPP1Bprotein biosynthesis, translational elongation ->
macromolecule biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, GAL4, RAP1, RFX1
|YMR013C|SEC59protein-ER targeting, protein amino acid glycosylation ->
cytoplasm organization and biogenesis, macromolecule biosynthesis, intracellular transport, secretory pathway, protein modification, glycoprotein metabolism, protein metabolism, protein transport
dolichol kinase activity ->
dolichol kinase activity
membrane ->
membrane
FHL1, NDD1, RAP1, RLM1, RME1
|YDR449C|UTP6processing of 20S pre-rRNA ->
cytoplasm organization and biogenesis, RNA metabolism, transcription
snoRNA binding ->
snoRNA binding
small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
FHL1, GAT3, HIR2, RAP1, RGM1, YAP5
YGL030WRPL30protein biosynthesis, rRNA processing, mRNA splicing, regulation of translation ->
cytoplasm organization and biogenesis, macromolecule biosynthesis, transcription\, DNA-dependent, RNA metabolism, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya), cytoplasm ->
cytoplasm, ribonucleoprotein complex
FHL1, GAT3, RAP1, SFP1
YOL120CRPL18Aprotein biosynthesis ->
macromolecule biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, MAL13, RAP1, YAP5
|YMR014W|BUD22bud site selection ->
cytokinesis, cytoplasm organization and biogenesis
nucleus ->
nucleus
CUP9, HAL9, HIR2, LEU3, NDD1, RLM1, ROX1, SMP1, YAP6
YOL121CRPS19Aprotein biosynthesis ->
macromolecule biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex
AZF1, FHL1, GCR1, GCR2, HAL9, MET31, MOT3, PDR1, RAP1, ROX1, RPH1, SMP1, YAP6, ZAP1
YPR080WTEF1translational elongation ->
macromolecule biosynthesis, protein metabolism
translation elongation factor activity ->
translation elongation factor activity
ribosome ->
cytoplasm, ribonucleoprotein complex
FHL1, PDR1, RAP1, YAP5
Main:protein metabolism (0.78)structural constituent of ribosome (0.50)cytoplasm (0.70)RAP1 FHL1 (0.80)
Score:0.720.250.620.689
P-value:3.639E-04 (translational elongation)6.981E-03 (translation elongation factor activity)1.478E-04 (ribonucleoprotein complex)6.276E-10 (FHL1)

RAP1(1) AND SWI5(1) AND MCM1'(1) => SimExpr(YOL120C) OR SimExpr(other) : 6 1

    EXPR: (0.121) SWI5 (P < 0.000) MCM1' (P < 0.000) RAP1 (P < 0.030)

ORFSYMBOLPFCTF
YKL006WRPL14Aprotein biosynthesis ->
protein biosynthesis
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosolic ribosome (sensu Eukarya), large ribosomal subunit
FHL1, GAT3, GRF10(Pho2), GTS1, RAP1
|YLR452C|SST2signal transduction, adaptation to pheromone during conjugation with cellular fusion ->
signal transduction, adaptation to pheromone during conjugation with cellular fusion
GTPase activator activity ->
GTPase activator activity
plasma membrane ->
plasma membrane
DIG1, FHL1, RAP1, STE12
YNL069CRPL16Bprotein biosynthesis ->
protein biosynthesis
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosolic ribosome (sensu Eukarya), large ribosomal subunit
FHL1, GAT3, PDR1, RAP1, RGM1, YAP5
YGL030WRPL30protein biosynthesis, rRNA processing, mRNA splicing, regulation of translation ->
protein biosynthesis, rRNA processing, mRNA splicing, regulation of translation
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya), cytoplasm ->
cytosolic ribosome (sensu Eukarya), cytoplasm, large ribosomal subunit
FHL1, GAT3, RAP1, SFP1
YOL120CRPL18Aprotein biosynthesis ->
protein biosynthesis
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosolic ribosome (sensu Eukarya), large ribosomal subunit
FHL1, MAL13, RAP1, YAP5
YDR450WRPS18Aprotein biosynthesis ->
protein biosynthesis
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
cytosolic ribosome (sensu Eukarya), eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, small ribosomal subunit
FHL1, GAT3, HIR2, RAP1, RGM1, YAP5
YLR344WRPL26Aprotein biosynthesis ->
protein biosynthesis
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosolic ribosome (sensu Eukarya), large ribosomal subunit
FHL1, RAP1
Main:protein biosynthesis (0.86)structural constituent of ribosome (0.86)cytosolic ribosome (sensu Eukarya) (0.86)RAP1 FHL1 (1.00)
Score:0.710.710.711.000
P-value:1.319E-04 (protein biosynthesis)2.360E-06 (structural constituent of ribosome)5.663E-07 (cytosolic ribosome (sensu Eukarya))2.380E-10 (FHL1)

RAP1(1) AND ALPHA1'(1) AND MCM1'(1) => SimExpr(YOL120C) : 7

    EXPR: (0.112) ALPHA1' (P < 0.000) MCM1' (P < 0.000) RAP1 (P < 0.022)

ORFSYMBOLPFCTF
YGR254WENO1gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism
phosphopyruvate hydratase activity ->
phosphopyruvate hydratase activity
phosphopyruvate hydratase complex, cytoplasm ->
cytosol, cytoplasm
FKH2, MSN4, PDR1, SWI5, YAP5
YDL130WRPP1Bprotein biosynthesis, translational elongation ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, GAL4, RAP1, RFX1
YPL090CRPS6Aprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
cytosol, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome
FHL1, GAT3, INO4, RAP1, YAP5
YMR142CRPL13Bprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, GAT3, RAP1, RGM1, YAP5
YOL120CRPL18Aprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, MAL13, RAP1, YAP5
YGR214WRPS0Aprotein biosynthesis, ribosomal small subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
cytosol, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome
FHL1, RAP1
YLR344WRPL26Aprotein biosynthesis ->
biosynthesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, RAP1
Main:biosynthesis (1.00)structural constituent of ribosome (0.86)cytosol (1.00)RAP1 FHL1 (0.86)
Score:1.000.711.000.857
P-value:1.173E-04 (protein biosynthesis)1.348E-06 (structural constituent of ribosome)7.722E-07 (cytosolic ribosome (sensu Eukarya))5.806E-08 (FHL1)

CSRE(1) AND HAP234(1) => SimExpr(YOR136W) OR SimExpr(other) : 5 1

    EXPR: (0.172) CSRE (P < 0.000) HAP234 (P < 0.007)

ORFSYMBOLPFCTF
|YKL141W|SDH3oxidative phosphorylation\, succinate to ubiquinone, tricarboxylic acid cycle ->
electron transport, carbohydrate metabolism, phosphorus metabolism, energy pathways
succinate dehydrogenase activity ->
succinate dehydrogenase activity
respiratory chain complex II (sensu Eukarya) ->
cytoplasm, respiratory chain complex II, succinate dehydrogenase complex (ubiquinone), inner membrane
YPR145WASN1asparagine biosynthesis ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis
asparagine synthase (glutamine-hydrolyzing) activity ->
asparagine synthase (glutamine-hydrolyzing) activity
DAL81, GCN4, GLN3, MET4, RAP1, SUM1
YLR304CACO1tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis, propionate metabolism ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis
aconitate hydratase activity ->
aconitate hydratase activity
cytosol, mitochondrial matrix ->
cytoplasm
CIN5, YAP6
YNL069CRPL16Bprotein biosynthesis ->
biosynthesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, GAT3, PDR1, RAP1, RGM1, YAP5
YOR136WIDH2tricarboxylic acid cycle, isocitrate metabolism, glutamate biosynthesis ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis
isocitrate dehydrogenase (NAD+) activity ->
isocitrate dehydrogenase (NAD+) activity
mitochondrial matrix, mitochondrion ->
cytoplasm
MET4
YFR033CQCR6aerobic respiration, oxidative phosphorylation\, ubiquinone to cytochrome c ->
energy pathways, electron transport, phosphorus metabolism
ubiquinol-cytochrome c reductase activity ->
ubiquinol-cytochrome c reductase activity
mitochondrion, respiratory chain complex III (sensu Eukarya) ->
cytoplasm, respiratory chain complex III, inner membrane
HAP4, MBP1
Main:biosynthesis (0.67)RNA binding (0.17)cytoplasm (1.00)RAP1 MET4 (0.40)
Score:0.730.001.000.200
P-value:4.809E-05 (tricarboxylic acid cycle)3.006E-02 (oxidoreductase activity)7.682E-03 (mitochondrial electron transport chain)5.318E-02 (MET4)

RAP1(1) AND MCM1'(1) => SimExpr(YGR254W) OR SimExpr(other) : 18 2

RAP1(1) AND ALPHA1(1) AND SFF(1) => SimExpr(YGR254W) OR SimExpr(other) : 14 3

    EXPR: (0.232) SFF (P < 0.000) RAP1 (P < 0.038) ALPHA1 (P < 0.000)

ORFSYMBOLPFCTF
YMR116CASC1cytoplasm ->
cytoplasm
FHL1, RAP1
|YMR224C|MRE11DNA repair, double-strand break repair via nonhomologous end-joining, meiotic DNA double-strand break formation, meiotic DNA double-strand break processing, double-strand break repair via break-induced replication ->
DNA metabolism, cell proliferation, catabolism
endonuclease activity, 3'-5' exonuclease activity, protein binding ->
endonuclease activity, 3'-5' exonuclease activity, protein binding
nucleus ->
nucleus
RAP1
YLR249WYEF3translational elongation ->
biosynthesis, protein metabolism
translation elongation factor activity ->
translation elongation factor activity
ribosome ->
cytoplasm, ribonucleoprotein complex
INO2, INO4
|YKR092C|SRP40nucleocytoplasmic transport ->
transport
chaperone activity ->
chaperone activity
nucleolus ->
nucleus
CUP9, MET4, RAP1
YKL006WRPL14Aprotein biosynthesis ->
biosynthesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, GAT3, GRF10(Pho2), GTS1, RAP1
YKR057WRPS21Aprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex
ABF1, FHL1
YGR254WENO1gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism
phosphopyruvate hydratase activity ->
phosphopyruvate hydratase activity
phosphopyruvate hydratase complex, cytoplasm ->
cytoplasm
FKH2, MSN4, PDR1, SWI5, YAP5
YJR139CHOM6homoserine biosynthesis, methionine metabolism, threonine metabolism ->
amine metabolism, sulfur metabolism, biosynthesis, amino acid and derivative metabolism, organic acid metabolism
homoserine dehydrogenase activity ->
homoserine dehydrogenase activity
HMS1, RAP1
YGL115WSNF4regulation of transcription from Pol II promoter, peroxisome organization and biogenesis ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
protein kinase activator activity ->
protein kinase activator activity
plasma membrane, nucleus, cytoplasm ->
plasma membrane, nucleus, cytoplasm
BAS1, CAD1, MAC1, NRG1, PDR1, RAP1, SMP1, YAP5
YML073CRPL6Aprotein biosynthesis, ribosomal large subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, GAT3, RAP1, YAP5
YKL180WRPL17Aprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya), cytoplasm ->
cytoplasm, ribonucleoprotein complex
FHL1, GAT3, RAP1
YMR231WPEP5nonselective vesicle docking, homotypic vacuole fusion (non-autophagic), Golgi to endosome transport, late endosome to vacuole transport ->
cell organization and biogenesis, transport, vesicle-mediated transport
vacuolar membrane (sensu Fungi) ->
cytoplasm, vacuole
ARG81, DOT6, HAL9, HAP2, MCM1, YAP1
YKL152CGPM1gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism
phosphoglycerate mutase activity ->
phosphoglycerate mutase activity
cytosol ->
cytoplasm
GCR1, GCR2, HSF1, RAP1
YML026CRPS18Bprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex
FHL1, GAT3, RAP1, RGM1, SWI4, YAP5
YPL131WRPL5protein biosynthesis, ribosomal large subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, GAT3, RAP1
|YDL043C|PRP11spliceosome assembly ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
RNA binding ->
RNA binding
snRNP U2 ->
nucleus, ribonucleoprotein complex
DAL81, STP1
YGR085CRPL11Bprotein biosynthesis, ribosomal large subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, MIG1
Main:biosynthesis (0.69)structural constituent of ribosome (0.47)cytoplasm (0.81)RAP1 (0.65)
Score:0.550.230.770.522
P-value:3.514E-03 (ribosomal large subunit assembly and maintenance)2.744E-04 (structural constituent of ribosome)7.319E-05 (cytosolic ribosome (sensu Eukarya))8.753E-09 (RAP1)

RAP1(1) AND ALPHA1(1) AND SFF'(1) => SimExpr(YGR254W) OR SimExpr(other) : 14 4

    EXPR: (0.237) SFF' (P < 0.000) RAP1 (P < 0.072) ALPHA1 (P < 0.000)

ORFSYMBOLPFCTF
YMR116CASC1cytoplasm ->
cytoplasm
FHL1, RAP1
|YMR224C|MRE11DNA repair, double-strand break repair via nonhomologous end-joining, meiotic DNA double-strand break formation, meiotic DNA double-strand break processing, double-strand break repair via break-induced replication ->
DNA metabolism, cell proliferation, catabolism
endonuclease activity, 3'-5' exonuclease activity, protein binding ->
endonuclease activity, 3'-5' exonuclease activity, protein binding
nucleus ->
nucleus
RAP1
YLR249WYEF3translational elongation ->
biosynthesis, protein metabolism
translation elongation factor activity ->
translation elongation factor activity
ribosome ->
cytoplasm, ribonucleoprotein complex
INO2, INO4
|YKR092C|SRP40nucleocytoplasmic transport ->
transport
chaperone activity ->
chaperone activity
nucleolus ->
nucleus
CUP9, MET4, RAP1
YKL006WRPL14Aprotein biosynthesis ->
biosynthesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, GAT3, GRF10(Pho2), GTS1, RAP1
YKR057WRPS21Aprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex
ABF1, FHL1
YGR254WENO1gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism
phosphopyruvate hydratase activity ->
phosphopyruvate hydratase activity
phosphopyruvate hydratase complex, cytoplasm ->
cytoplasm
FKH2, MSN4, PDR1, SWI5, YAP5
YJR139CHOM6homoserine biosynthesis, methionine metabolism, threonine metabolism ->
amine metabolism, sulfur metabolism, biosynthesis, amino acid and derivative metabolism, organic acid metabolism
homoserine dehydrogenase activity ->
homoserine dehydrogenase activity
HMS1, RAP1
|YMR013C|SEC59protein-ER targeting, protein amino acid glycosylation ->
cell organization and biogenesis, biosynthesis, protein modification, protein metabolism, transport
dolichol kinase activity ->
dolichol kinase activity
membrane ->
membrane
FHL1, NDD1, RAP1, RLM1, RME1
YGL115WSNF4regulation of transcription from Pol II promoter, peroxisome organization and biogenesis ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
protein kinase activator activity ->
protein kinase activator activity
plasma membrane, nucleus, cytoplasm ->
membrane, nucleus, cytoplasm
BAS1, CAD1, MAC1, NRG1, PDR1, RAP1, SMP1, YAP5
YML073CRPL6Aprotein biosynthesis, ribosomal large subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, GAT3, RAP1, YAP5
YKL180WRPL17Aprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya), cytoplasm ->
cytoplasm, ribonucleoprotein complex
FHL1, GAT3, RAP1
YMR231WPEP5nonselective vesicle docking, homotypic vacuole fusion (non-autophagic), Golgi to endosome transport, late endosome to vacuole transport ->
cell organization and biogenesis, transport, vesicle-mediated transport
vacuolar membrane (sensu Fungi) ->
cytoplasm, vacuole
ARG81, DOT6, HAL9, HAP2, MCM1, YAP1
YKL152CGPM1gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism
phosphoglycerate mutase activity ->
phosphoglycerate mutase activity
cytosol ->
cytoplasm
GCR1, GCR2, HSF1, RAP1
YML026CRPS18Bprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex
FHL1, GAT3, RAP1, RGM1, SWI4, YAP5
YPL131WRPL5protein biosynthesis, ribosomal large subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, GAT3, RAP1
|YDL043C|PRP11spliceosome assembly ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
RNA binding ->
RNA binding
snRNP U2 ->
nucleus, ribonucleoprotein complex
DAL81, STP1
YGR085CRPL11Bprotein biosynthesis, ribosomal large subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, MIG1
Main:biosynthesis (0.71)structural constituent of ribosome (0.44)cytoplasm (0.76)RAP1 (0.67)
Score:0.590.200.680.549
P-value:1.754E-03 (biosynthesis)4.264E-04 (structural constituent of ribosome)1.154E-04 (cytosolic ribosome (sensu Eukarya))8.002E-10 (RAP1)

RAP1(1) AND ALPHA1(1) AND MCM1'(1) => SimExpr(YGR254W) : 9

    EXPR: (0.189) MCM1' (P < 0.000) RAP1 (P < 0.005) ALPHA1 (P < 0.000)

ORFSYMBOLPFCTF
YKL006WRPL14Aprotein biosynthesis ->
biosynthesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, GAT3, GRF10(Pho2), GTS1, RAP1
YIL018WRPL2Bprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, GAT3, PDR1, RAP1, RGM1, SWI5, YAP5
YGR254WENO1gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism
phosphopyruvate hydratase activity ->
phosphopyruvate hydratase activity
phosphopyruvate hydratase complex, cytoplasm ->
cytosol, cytoplasm
FKH2, MSN4, PDR1, SWI5, YAP5
YDL130WRPP1Bprotein biosynthesis, translational elongation ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, GAL4, RAP1, RFX1
YJR139CHOM6homoserine biosynthesis, methionine metabolism, threonine metabolism ->
amine metabolism, sulfur metabolism, biosynthesis, amino acid and derivative metabolism, organic acid metabolism
homoserine dehydrogenase activity ->
homoserine dehydrogenase activity
HMS1, RAP1
YMR142CRPL13Bprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, GAT3, RAP1, RGM1, YAP5
YML073CRPL6Aprotein biosynthesis, ribosomal large subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, GAT3, RAP1, YAP5
YKL152CGPM1gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism
phosphoglycerate mutase activity ->
phosphoglycerate mutase activity
cytosol ->
cytosol
GCR1, GCR2, HSF1, RAP1
YGR085CRPL11Bprotein biosynthesis, ribosomal large subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, MIG1
Main:biosynthesis (1.00)structural constituent of ribosome (0.67)cytosol (1.00)RAP1 (0.78)
Score:1.000.421.000.806
P-value:3.235E-05 (biosynthesis)2.921E-05 (structural constituent of ribosome)9.879E-08 (cytosolic large ribosomal subunit (sensu Eukarya))9.189E-07 (FHL1)

CSRE(1) AND RAP1(1) AND MCM1'(1) => SimExpr(YGR254W) : 9

    EXPR: (0.191) MCM1' (P < 0.000) CSRE (P < 0.000) RAP1 (P < 0.002)

ORFSYMBOLPFCTF
YGR254WENO1gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism
phosphopyruvate hydratase activity ->
phosphopyruvate hydratase activity
phosphopyruvate hydratase complex, cytoplasm ->
cytosol, cytoplasm
FKH2, MSN4, PDR1, SWI5, YAP5
YNL069CRPL16Bprotein biosynthesis ->
biosynthesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, GAT3, PDR1, RAP1, RGM1, YAP5
YPL090CRPS6Aprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
cytosol, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome
FHL1, GAT3, INO4, RAP1, YAP5
YGL147CRPL9Aprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, MBP1, RAP1, SWI4
YML073CRPL6Aprotein biosynthesis, ribosomal large subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, GAT3, RAP1, YAP5
YGR214WRPS0Aprotein biosynthesis, ribosomal small subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
cytosol, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome
FHL1, RAP1
YDR450WRPS18Aprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
cytosol, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome
FHL1, GAT3, HIR2, RAP1, RGM1, YAP5
YKL152CGPM1gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism
phosphoglycerate mutase activity ->
phosphoglycerate mutase activity
cytosol ->
cytosol
GCR1, GCR2, HSF1, RAP1
YLR344WRPL26Aprotein biosynthesis ->
biosynthesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, RAP1
Main:biosynthesis (1.00)structural constituent of ribosome (0.78)cytosol (1.00)RAP1 (0.89)
Score:1.000.581.000.889
P-value:3.145E-05 (biosynthesis)7.679E-07 (structural constituent of ribosome)3.470E-08 (cytosol)1.004E-08 (FHL1)

RAP1(1) AND ALPHA1'(1) AND MCM1'(1) => SimExpr(YGR254W) : 7

REB1(1) AND ALPHA2(1) AND SWI5(1) => SimExpr(YOR025W) : 5

    EXPR: (0.181) ALPHA2 (P < 0.000) SWI5 (P < 0.000) REB1 (P < 0.000)

ORFSYMBOLPFCTF
YOR152CNO SYMBOLHIR2
YNL197CWHI3regulation of cell size ->
cell organization and biogenesis
RNA binding ->
RNA binding
REB1
YNL111CCYB5sterol biosynthesis ->
alcohol metabolism, biosynthesis, lipid metabolism
electron transporter activity ->
electron transporter activity
microsome ->
microsome
ABF1, GCR2, GTS1, NRG1, REB1, ROX1
YNL090WRHO2microtubule-based process, cell wall organization and biogenesis, small GTPase mediated signal transduction, establishment of cell polarity (sensu Saccharomyces), actin filament organization ->
signal transduction, cell organization and biogenesis, organelle organization and biogenesis
Rho small monomeric GTPase activity, signal transducer activity ->
Rho small monomeric GTPase activity, signal transducer activity
intracellular ->
intracellular
INO4, REB1
YOR025WHST3chromatin silencing at telomere, short-chain fatty acid metabolism ->
cell organization and biogenesis, lipid metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription, organic acid metabolism
DNA binding ->
DNA binding
intracellular ->
intracellular
IXR1, NDD1
Main:cell organization and biogenesis (0.75)DNA binding (0.25)intracellular (0.67)REB1 (0.60)
Score:0.670.000.330.300
P-value:1.465E-01 (lipid metabolism)7.055E-01 (binding)3.995E+00 (intracellular)5.118E-03 (REB1)

CSRE(1) AND HAP234(1) => SimExpr(YLR304C) : 6

CSRE(1) AND PDR(1) AND ATRepeat(1) => SimExpr(YLR304C) : 5

    EXPR: (0.171) PDR (P < 0.003) ATRepeat (P < 0.000) CSRE (P < 0.000)

ORFSYMBOLPFCTF
YGL062WPYC1NADPH regeneration, gluconeogenesis ->
coenzymes and prosthetic group metabolism, alcohol metabolism, carbohydrate metabolism, vitamin metabolism, biosynthesis, energy pathways
pyruvate carboxylase activity ->
pyruvate carboxylase activity
cytosol ->
cytoplasm
DIG1, GCR1, STE12
YKL141WSDH3oxidative phosphorylation\, succinate to ubiquinone, tricarboxylic acid cycle ->
electron transport, carbohydrate metabolism, phosphorus metabolism, energy pathways
succinate dehydrogenase activity ->
succinate dehydrogenase activity
respiratory chain complex II (sensu Eukarya) ->
cytoplasm, respiratory chain complex II, succinate dehydrogenase complex (ubiquinone), inner membrane
YLR304CACO1tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis, propionate metabolism ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis
aconitate hydratase activity ->
aconitate hydratase activity
cytosol, mitochondrial matrix ->
cytoplasm
CIN5, YAP6
YOR153WPDR5drug transport, response to drug ->
transport, response to abiotic stimulus
xenobiotic-transporting ATPase activity ->
xenobiotic-transporting ATPase activity
plasma membrane ->
plasma membrane
YAP6
YNL231CPDR16phospholipid transport, sterol biosynthesis, response to drug ->
transport, alcohol metabolism, response to abiotic stimulus, biosynthesis, lipid metabolism
phosphatidylinositol transporter activity ->
phosphatidylinositol transporter activity
cytoplasm ->
cytoplasm
HSF1, MBP1, SWI4, YAP1
Main:biosynthesis (0.60)pyruvate carboxylase activity (0.20)cytoplasm (0.80)YAP6 (0.50)
Score:0.600.000.600.167
P-value:2.167E-03 (main pathways of carbohydrate metabolism)5.353E-01 (transporter activity)7.999E-01 (cytosol)1.030E-01 (YAP6)

CSRE(1) AND RAP1(1) => SimExpr(YML073C) OR SimExpr(other) : 12 2

    EXPR: (0.158) CSRE (P < 0.000) RAP1 (P < 0.026)

ORFSYMBOLPFCTF
YOR096WRPS7Aprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex
FHL1, FKH2, RAP1
YGR254WENO1gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism
phosphopyruvate hydratase activity ->
phosphopyruvate hydratase activity
phosphopyruvate hydratase complex, cytoplasm ->
cytoplasm
FKH2, MSN4, PDR1, SWI5, YAP5
YNL069CRPL16Bprotein biosynthesis ->
biosynthesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, GAT3, PDR1, RAP1, RGM1, YAP5
YPL090CRPS6Aprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex
FHL1, GAT3, INO4, RAP1, YAP5
YJR145CRPS4Aprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya), cytoplasm ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex
ACE2, CIN5, FHL1, INO4, MTH1, RAP1, YAP6
|YOR213C|SAS5chromatin silencing at telomere ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription
acetyltransferase activity ->
acetyltransferase activity
nuclear chromosome\, telomeric region, nuclear chromatin ->
chromosome, nuclear chromosome
GRF10(Pho2), SUM1
YGL147CRPL9Aprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, MBP1, RAP1, SWI4
YML073CRPL6Aprotein biosynthesis, ribosomal large subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, GAT3, RAP1, YAP5
YGR214WRPS0Aprotein biosynthesis, ribosomal small subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex
FHL1, RAP1
YDR450WRPS18Aprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex
FHL1, GAT3, HIR2, RAP1, RGM1, YAP5
YKL152CGPM1gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism
phosphoglycerate mutase activity ->
phosphoglycerate mutase activity
cytosol ->
cytoplasm
GCR1, GCR2, HSF1, RAP1
YLR344WRPL26Aprotein biosynthesis ->
biosynthesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, RAP1
YOR312CRPL20Bprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, FKH2, GAT3, RAP1
|YDL043C|PRP11spliceosome assembly ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
RNA binding ->
RNA binding
snRNP U2 ->
nucleus, ribonucleoprotein complex
DAL81, STP1
Main:biosynthesis (0.86)structural constituent of ribosome (0.71)cytoplasm (0.86)RAP1 (0.79)
Score:0.760.530.840.670
P-value:8.659E-06 (protein biosynthesis)3.542E-09 (structural constituent of ribosome)2.930E-10 (cytosolic ribosome (sensu Eukarya))8.001E-12 (FHL1)

CSRE(1) AND RAP1(1) AND MCM1'(1) => SimExpr(YML073C) : 9

RAP1(1) AND ALPHA1(1) AND MCM1'(1) => SimExpr(YML073C) : 9

CSRE(1) AND RAP1(1) => SimExpr(YGL147C) OR SimExpr(other) : 12 2

CSRE(1) AND RAP1(1) AND MCM1'(1) => SimExpr(YGL147C) : 9

CSRE(1) AND RAP1(1) => SimExpr(YJR145C) OR SimExpr(other) : 11 3

ABF1(1) AND ALPHA1'(1) AND PAC(1) => SimExpr(YPR010C) : 5

    EXPR: (0.166) ABF1 (P < 0.000) ALPHA1' (P < 0.000) PAC (P < 0.000)

ORFSYMBOLPFCTF
YOL041CNOP12rRNA metabolism ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
RNA binding ->
RNA binding
nucleolus ->
nucleus
GTS1, MET31
YPR010CRPA135transcription from Pol I promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
DNA-directed RNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups
DNA-directed RNA polymerase I complex ->
nucleus
ROX1, SIG1
YNL292WPUS4tRNA modification ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
pseudouridylate synthase activity ->
carbon-oxygen lyase activity
mitochondrion, nucleus ->
cytoplasm, nucleus
RCS1
YNL112WDBP2RNA helicase activity ->
RNA binding
bud neck ->
site of polarized growth (sensu Fungi)
YKL014CNO SYMBOLABF1
Main:nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (1.00)RNA binding (0.50)nucleus (0.75)ABF1 (0.25)
Score:1.000.170.500.000
P-value:2.994E-01 (RNA metabolism)3.258E-01 (RNA binding)9.452E-02 (nucleolus)3.281E-01 (SIG1)

CSRE(1) AND RAP1(1) => SimExpr(YOR312C) OR SimExpr(other) : 12 2

CSRE(1) AND HAP234(1) => SimExpr(YFR033C) OR SimExpr(other) : 5 1

CSRE(1) AND ALPHA1(1) AND SFF'(1) AND CCA(1) => SimExpr(YOL082W) OR SimExpr(other) : 5 2

    EXPR: (0.218) SFF' (P < 0.000) CCA (P < 0.002) CSRE (P < 0.000) ALPHA1 (P < 0.000)

ORFSYMBOLPFCTF
|YKL141W|SDH3oxidative phosphorylation\, succinate to ubiquinone, tricarboxylic acid cycle ->
electron transport, carbohydrate metabolism, phosphorus metabolism, energy pathways
succinate dehydrogenase activity ->
succinate dehydrogenase activity
respiratory chain complex II (sensu Eukarya) ->
cytoplasm, respiratory chain complex II, succinate dehydrogenase complex (ubiquinone), inner membrane
YOR152CNO SYMBOLHIR2
YLR328WNMA1nicotinamide adenine dinucleotide metabolism ->
coenzymes and prosthetic group metabolism, vitamin metabolism
nicotinamide-nucleotide adenylyltransferase activity ->
nicotinamide-nucleotide adenylyltransferase activity
CIN5, MSN1, ROX1
YOL082WCVT19protein-vacuolar targeting ->
cell organization and biogenesis, protein metabolism, transport
protein binding ->
protein binding
vacuole, peripheral membrane protein of membrane fraction, cytoplasm ->
cytoplasm, membrane fraction
GTS1, MCM1, RAP1, STE12
YMR008CPLB1glycerophospholipid metabolism ->
lipid metabolism
lysophospholipase activity ->
lysophospholipase activity
cell wall (sensu Fungi) ->
cell wall
RAP1
|YLR406C|RPL31Bprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, FKH1, MTH1, RAP1
YKR003WOSH6steroid biosynthesis ->
biosynthesis, lipid metabolism
oxysterol binding ->
oxysterol binding
Main:biosynthesis (0.33)nicotinamide-nucleotide adenylyltransferase activity (0.17)cytoplasm (0.75)RAP1 (0.60)
Score:0.200.000.500.300
P-value:2.539E-01 (lipid metabolism)2.769E+00 (binding)4.385E+00 (cytoplasm)7.002E-02 (RAP1)

RAP1(1) AND MCM1'(1) => SimExpr(YPL090C) OR SimExpr(other) : 19 1

CSRE(1) AND RAP1(1) => SimExpr(YPL090C) OR SimExpr(other) : 12 2

CSRE(1) AND RAP1(1) AND MCM1'(1) => SimExpr(YPL090C) : 9

RAP1(1) AND ALPHA1'(1) AND MCM1'(1) => SimExpr(YPL090C) : 7

CSRE(1) AND GCN4(1) => SimExpr(YPR145W) OR SimExpr(other) : 5 2

    EXPR: (0.223) GCN4 (P < 0.030) CSRE (P < 0.022)

ORFSYMBOLPFCTF
|YGL184C|STR3methionine biosynthesis ->
amine metabolism, sulfur metabolism, biosynthesis, amino acid and derivative metabolism, organic acid metabolism
cystathionine beta-lyase activity ->
cystathionine beta-lyase activity
peroxisome ->
cytoplasm
INO4, MET31, MET4
|YNL019C|NO SYMBOL
YLR355CILV5branched chain family amino acid biosynthesis, mitochondrial genome maintenance ->
amine metabolism, cell organization and biogenesis, amino acid and derivative metabolism, organic acid metabolism, biosynthesis
ketol-acid reductoisomerase activity ->
ketol-acid reductoisomerase activity
mitochondrion ->
cytoplasm
GCN4, MET4
YPR145WASN1asparagine biosynthesis ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis
asparagine synthase (glutamine-hydrolyzing) activity ->
asparagine synthase (glutamine-hydrolyzing) activity
DAL81, GCN4, GLN3, MET4, RAP1, SUM1
YGL207WSPT16chromatin modeling, regulation of global transcription from Pol II promoter, RNA elongation from Pol II promoter ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, DNA metabolism
transcriptional elongation regulator activity ->
transcriptional elongation regulator activity
alpha DNA polymerase\:primase complex, nuclear chromatin, transcription elongation factor complex ->
nucleus, chromosome
RTG1
YNL098CRAS2pseudohyphal growth, sporulation (sensu Saccharomyces), adenylate cyclase activation, RAS protein signal transduction ->
cell organization and biogenesis, sporulation, signal transduction
RAS small monomeric GTPase activity ->
RAS small monomeric GTPase activity
plasma membrane ->
plasma membrane
ACE2, SKN7
YOL092WNO SYMBOLMAC1
Main:cell organization and biogenesis (0.60)RAS small monomeric GTPase activity (0.20)cytoplasm (0.50)MET4 (0.50)
Score:0.600.000.170.200
P-value:1.165E-02 (amino acid biosynthesis)1.628E+00 (enzyme activity)4.869E+00 (cytoplasm)1.489E-03 (MET4)

CSRE(1) AND HAP234(1) => SimExpr(YPR145W) : 6

CSRE(1) AND MCB(1) => SimExpr(YMR076C) OR SimExpr(other) : 5 2

    EXPR: (0.191) MCB (P < 0.121) CSRE (P < 0.000)

ORFSYMBOLPFCTF
YDR309CGIC2axial budding, Rho protein signal transduction, establishment of cell polarity (sensu Saccharomyces) ->
axial budding, small GTPase mediated signal transduction, organelle organization and biogenesis
small GTPase regulatory/interacting protein activity ->
small GTPase regulatory/interacting protein activity
actin cap (sensu Saccharomyces), bud tip, shmoo tip, incipient bud site ->
cell cortex, site of polarized growth (sensu Fungi), incipient bud site, cytoplasm
ASH1, HSF1, MBP1, PHD1, RLM1, SKN7, STB1, STE12, SWI4, SWI6
|YJR006W|HYS2leading strand elongation, lagging strand elongation, mutagenesis, base-excision repair, nucleotide-excision repair, postreplication repair, mismatch repair ->
mutagenesis, DNA repair, postreplication repair, DNA replication and chromosome cycle, mitotic cell cycle, DNA metabolism
delta DNA polymerase activity ->
delta DNA polymerase activity
delta DNA polymerase complex ->
cytoplasm, nucleus
ABF1
YML027WYOX1negative regulation of transcription from Pol II promoter\, mitotic, regulation of mitotic cell cycle ->
mitotic cell cycle, M phase, regulation of transcription, nuclear division, transcription\, DNA-dependent, regulation of cell cycle
specific transcriptional repressor activity, DNA binding ->
specific transcriptional repressor activity, DNA binding
nucleus ->
nucleus
MBP1, SWI4, SWI6
YDR134CNO SYMBOLASH1, NRG1, SOK2, SWI4
|YMR279C|NO SYMBOLIXR1, MIG1, MTH1, RFX1, SWI4, SWI6
YMR076CPDS5mitotic sister chromatid cohesion, mitotic chromosome condensation ->
DNA replication and chromosome cycle, M phase, mitotic cell cycle
structural molecule activity ->
structural molecule activity
condensed nuclear chromosome ->
chromosome, nucleus
FKH2, MBP1, SWI6
YHR110WERP5secretory pathway ->
secretory pathway
integral to membrane ->
integral to membrane
DOT6, RGT1
Main:mitotic cell cycle (0.60)DNA binding (0.25)nucleus (0.60)SWI4 SWI6 (0.57)
Score:0.300.000.400.429
P-value:1.664E-01 (mitotic cell cycle)2.000E+002.837E+00 (nucleus)5.504E-04 (SWI6)

ALPHA1(1) AND MCB(1) => SimExpr(YMR076C) OR SimExpr(other) : 22 10

    EXPR: (0.203) MCB (P < 0.055) ALPHA1 (P < 0.000)

ORFSYMBOLPFCTF
YMR179WSPT21regulation of transcription from Pol II promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
MBP1, STB1, SWI4, SWI6, UGA3
YML027WYOX1negative regulation of transcription from Pol II promoter\, mitotic, regulation of mitotic cell cycle ->
transcription, cell cycle
specific transcriptional repressor activity, DNA binding ->
specific transcriptional repressor activity, DNA binding
nucleus ->
intracellular
MBP1, SWI4, SWI6
|YPR185W|APG13protein-vacuolar targeting, autophagy ->
cell organization and biogenesis, autophagy, protein metabolism, transport
protein binding ->
protein binding
extrinsic to membrane ->
extrinsic to membrane
MET4, SWI6
YDL003WMCD1mitotic sister chromatid cohesion, mitotic chromosome condensation ->
cell proliferation, cell cycle
nuclear cohesin complex ->
intracellular
CIN5, MBP1, SWI6
|YMR125W|STO1mRNA splicing ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
mRNA binding ->
RNA binding
commitment complex, snRNA cap binding complex ->
intracellular
ABF1, FZF1, HAP3, MET31, RTG1, SRD1, SUM1, YAP6, ZAP1
YGR189CCRH1cell wall, incipient bud site ->
cell wall, intracellular
GRF10(Pho2), MBP1, RLM1, STE12, SWI4, SWI5
|YJR030C|NO SYMBOLMBP1, PHO4, RTG1, SWI6
YNL233WBNI4cytokinesis ->
cell proliferation
protein binding ->
protein binding
contractile ring (sensu Saccharomyces) ->
site of polarized growth (sensu Fungi), intracellular
PHO4
YGR109CCLB6regulation of CDK activity, G1/S transition of mitotic cell cycle, premeiotic DNA synthesis ->
cell proliferation, cell cycle, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
cyclin-dependent protein kinase\, regulator activity ->
transferase activity\, transferring phosphorus-containing groups, protein kinase regulator activity
MBP1, STB1, SWI4, SWI6
|YMR102C|NO SYMBOL
YPR135WCTF4DNA dependent DNA replication, DNA repair ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, cell proliferation
DNA binding ->
DNA binding
nucleus ->
intracellular
BAS1, DIG1, FZF1
YNL077WAPJ1chaperone activity ->
chaperone activity
HSF1, MSN4
YNL039WBDP1transcription initiation from Pol III promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
RNA polymerase III transcription factor activity ->
RNA polymerase III transcription factor activity
transcription factor TFIIIB complex ->
intracellular
YMR076CPDS5mitotic sister chromatid cohesion, mitotic chromosome condensation ->
cell proliferation, cell cycle
structural molecule activity ->
structural molecule activity
condensed nuclear chromosome ->
intracellular
FKH2, MBP1, SWI6
|YJL095W|BCK1protein amino acid phosphorylation, protein kinase cascade, response to nutrients, establishment of cell polarity (sensu Saccharomyces) ->
phosphorus metabolism, signal transduction, response to extracellular stimulus, cell organization and biogenesis, protein metabolism, response to abiotic stimulus
MAP kinase kinase kinase activity ->
transferase activity\, transferring phosphorus-containing groups
intracellular ->
intracellular
YAP1
YFR027WECO1sister chromatid cohesion, DNA replication, DNA repair ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, cell proliferation
acetyltransferase activity ->
transferase activity\, transferring acyl groups
nuclear chromatin ->
intracellular
YNL102WPOL1DNA replication\, priming, DNA replication initiation, lagging strand elongation, DNA repair synthesis ->
DNA metabolism, cell proliferation
alpha DNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups
alpha DNA polymerase\:primase complex ->
intracellular
LEU3, MBP1
|YGR085C|RPL11Bprotein biosynthesis, ribosomal large subunit assembly and maintenance ->
biosynthesis, cell organization and biogenesis, protein metabolism
structural constituent of ribosome ->
structural molecule activity
cytosolic large ribosomal subunit (sensu Eukarya) ->
intracellular
FHL1, MIG1
YLR313CSPH1actin filament organization, polar budding, pseudohyphal growth, Rho protein signal transduction, establishment of cell polarity (sensu Saccharomyces) ->
asexual reproduction, signal transduction, cell organization and biogenesis
cytoskeletal regulatory protein binding ->
protein binding
polarisome, actin cap (sensu Saccharomyces), shmoo tip ->
site of polarized growth (sensu Fungi), site of polarized growth (sensu Saccharomyces), intracellular
GCR1, RPH1
YML012WERV25ER to Golgi transport ->
transport, vesicle-mediated transport
COPII-coated vesicle ->
intracellular
ABF1
YDR097CMSH6mismatch repair ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, cell proliferation
ATPase activity, ATP binding, DNA binding ->
purine nucleotide binding, DNA binding, hydrolase activity\, acting on acid anhydrides
nucleus ->
intracellular
DOT6, MBP1, SWI6
|YOL006C|TOP1negative regulation of recombination within rDNA repeats, DNA topological change, DNA strand elongation, chromatin assembly/disassembly, regulation of transcription from Pol II promoter, RNA elongation from Pol II promoter, mitotic chromosome condensation, nuclear migration ->
cell organization and biogenesis, cell cycle, mitotic cell cycle, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
DNA topoisomerase type I activity ->
other isomerase activity
nucleus ->
intracellular
REB1
|YPL140C|MKK2protein amino acid phosphorylation, signal transduction ->
phosphorus metabolism, signal transduction, protein metabolism
MAP kinase kinase activity ->
transferase activity\, transferring phosphorus-containing groups
intracellular ->
intracellular
FKH1, FKH2
YKR077WNO SYMBOL
YOR284WHUA2RFX1, YAP6
|YLR430W|SEN135S primary transcript processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
ATP dependent RNA helicase activity ->
RNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides
nucleolus ->
intracellular
ARG80, GTS1, HAP5, RTG3, SIP4
|YNR028W|CPR8peptidyl-prolyl cis-trans isomerase activity ->
cis-trans isomerase activity
ASH1, DIG1, MCM1
YOR144CELG1negative regulation of DNA transposition, negative regulation of DNA recombination ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
YJL206C
YDR134CNO SYMBOLASH1, NRG1, SOK2, SWI4
YGL225WVRG4nucleotide-sugar transport, N-linked glycosylation, lipid glycosylation ->
transport, biosynthesis, lipid metabolism, protein metabolism
nucleotide-sugar transporter activity ->
nucleotide-sugar transporter activity
Golgi apparatus ->
intracellular
YNL206CRTT106negative regulation of DNA transposition ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
MSS11, SIP4, SUM1
YNL082WPMS1mismatch repair, meiosis ->
DNA metabolism, cell proliferation
ATPase activity, ATP binding, DNA binding ->
purine nucleotide binding, DNA binding, hydrolase activity\, acting on acid anhydrides
nuclear chromosome ->
intracellular
MTH1
Main:nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.46)DNA binding (0.19)intracellular (0.95)MBP1 (0.33)
Score:0.420.090.900.162
P-value:1.223E-03 (DNA replication)2.092E+00 (isomerase activity)5.299E-01 (chromosome)1.349E-05 (MBP1)

CSRE(1) AND ALPHA1(1) AND SFF'(1) AND CCA(1) => SimExpr(YMR008C) OR SimExpr(other) : 5 2

mRRPE(1) AND Leu3(1) => SimExpr(YLR355C) OR SimExpr(other) : 5 1

    EXPR: (0.179) mRRPE (P < 0.004) Leu3 (P < 0.026)

ORFSYMBOLPFCTF
YLR355CILV5branched chain family amino acid biosynthesis, mitochondrial genome maintenance ->
amine metabolism, cell organization and biogenesis, amino acid and derivative metabolism, organic acid metabolism, biosynthesis
ketol-acid reductoisomerase activity ->
oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor
mitochondrion ->
cytoplasm
GCN4, MET4
YJR016CILV3branched chain family amino acid biosynthesis ->
amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis
dihydroxy-acid dehydratase activity ->
hydro-lyase activity
mitochondrion ->
cytoplasm
YKL029CMAE1pyruvate metabolism, amino acid metabolism ->
amine metabolism, organic acid metabolism, amino acid and derivative metabolism
malate dehydrogenase (oxaloacetate decarboxylating) activity ->
malate dehydrogenase activity, oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor
mitochondrion ->
cytoplasm
ABF1, CIN5
YKR071CDRE2CAD1, HSF1, YAP1, YAP3
YPR074CTKL1pentose-phosphate shunt ->
coenzymes and prosthetic group metabolism, alcohol metabolism, water-soluble vitamin metabolism, carbohydrate metabolism, energy derivation by oxidation of organic compounds, catabolism
transketolase activity ->
transketolase and transaldolase activity
cytoplasm ->
cytoplasm
REB1
|YDR043C|NRG1response to pH, glucose metabolism, regulation of transcription from Pol II promoter, invasive growth ->
cell homeostasis, alcohol metabolism, cell organization and biogenesis, response to abiotic stimulus, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, carbohydrate metabolism
transcriptional repressor activity, DNA binding ->
transcriptional repressor activity, DNA binding
nucleus ->
nucleus
NRG1, SKN7
Main:amino acid and derivative metabolism (0.60)oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor (0.40)cytoplasm (0.80)YAP1 (0.20)
Score:0.500.100.600.000
P-value:7.579E-03 (branched chain family amino acid biosynthesis)4.606E-02 (oxidoreductase activity\, acting on the CH-OH group of donors\, NAD or NADP as acceptor)1.995E-01 (mitochondrion)1.412E-01 (YAP3)

CSRE(1) AND RAP1(1) => SimExpr(YDR450W) OR SimExpr(other) : 12 2

CSRE(1) AND RAP1(1) AND MCM1'(1) => SimExpr(YDR450W) : 9

ALPHA1(1) AND PDR(1) AND ATRepeat(1) => SimExpr(YOR153W) OR SimExpr(other) : 6 2

    EXPR: (0.193) PDR (P < 0.001) ATRepeat (P < 0.000) ALPHA1 (P < 0.000)

ORFSYMBOLPFCTF
|YGL062W|PYC1NADPH regeneration, gluconeogenesis ->
coenzymes and prosthetic group metabolism, alcohol metabolism, carbohydrate metabolism, vitamin metabolism, biosynthesis, energy pathways
pyruvate carboxylase activity ->
pyruvate carboxylase activity
cytosol ->
cytoplasm
DIG1, GCR1, STE12
YOR273CTPO4polyamine transport ->
transport
spermine transporter activity, spermidine transporter activity ->
spermine transporter activity, spermidine transporter activity
plasma membrane, vacuolar membrane ->
plasma membrane, cytoplasm
ARO80, BAS1, FZF1, HIR1, IME4, NRG1, PDR1, PHO4, SFP1, SKN7, STP1
YOR153WPDR5drug transport, response to drug ->
transport, response to abiotic stimulus
xenobiotic-transporting ATPase activity ->
xenobiotic-transporting ATPase activity
plasma membrane ->
plasma membrane
YAP6
|YGL057C|NO SYMBOL
YGL197WMDS3sporulation ->
sporulation
cytoplasm ->
cytoplasm
MTH1
YKL141WSDH3oxidative phosphorylation\, succinate to ubiquinone, tricarboxylic acid cycle ->
electron transport, carbohydrate metabolism, phosphorus metabolism, energy pathways
succinate dehydrogenase activity ->
succinate dehydrogenase activity
respiratory chain complex II (sensu Eukarya) ->
cytoplasm, respiratory chain complex II, succinate dehydrogenase complex (ubiquinone), inner membrane
YNL231CPDR16phospholipid transport, sterol biosynthesis, response to drug ->
transport, alcohol metabolism, response to abiotic stimulus, biosynthesis, lipid metabolism
phosphatidylinositol transporter activity ->
phosphatidylinositol transporter activity
cytoplasm ->
cytoplasm
HSF1, MBP1, SWI4, YAP1
YGR281WYOR1transport, response to drug ->
transport, response to abiotic stimulus
xenobiotic-transporting ATPase activity ->
xenobiotic-transporting ATPase activity
plasma membrane ->
plasma membrane
Main:transport (0.57)xenobiotic-transporting ATPase activity (0.33)cytoplasm (0.71)YAP1 (0.20)
Score:0.380.070.620.000
P-value:2.468E-04 (response to drug)4.681E-03 (xenobiotic-transporting ATPase activity)8.119E-02 (plasma membrane)1.000E+00

ALPHA1(1) AND MCB(1) => SimExpr(YML027W) OR SimExpr(other) : 22 10

ALPHA1(1) AND MCB(1) AND MCM1'(1) => SimExpr(YML027W) OR SimExpr(other) : 7 3

    EXPR: (0.215) MCB (P < 0.253) MCM1' (P < 0.000) ALPHA1 (P < 0.000)

ORFSYMBOLPFCTF
YML027WYOX1negative regulation of transcription from Pol II promoter\, mitotic, regulation of mitotic cell cycle ->
mitotic cell cycle, M phase, regulation of transcription, nuclear division, transcription\, DNA-dependent, regulation of cell cycle
specific transcriptional repressor activity, DNA binding ->
specific transcriptional repressor activity, DNA binding
nucleus ->
nucleus
MBP1, SWI4, SWI6
YGR189CCRH1cell wall, incipient bud site ->
cell wall, incipient bud site
GRF10(Pho2), MBP1, RLM1, STE12, SWI4, SWI5
YGR109CCLB6regulation of CDK activity, G1/S transition of mitotic cell cycle, premeiotic DNA synthesis ->
DNA replication and chromosome cycle, regulation of cell cycle, mitotic cell cycle, DNA metabolism
cyclin-dependent protein kinase\, regulator activity ->
cyclin-dependent protein kinase\, regulator activity
MBP1, STB1, SWI4, SWI6
|YMR102C|NO SYMBOL
YPR135WCTF4DNA dependent DNA replication, DNA repair ->
DNA replication and chromosome cycle, DNA repair, mitotic cell cycle, DNA metabolism
DNA binding ->
DNA binding
nucleus ->
nucleus
BAS1, DIG1, FZF1
|YGR085C|RPL11Bprotein biosynthesis, ribosomal large subunit assembly and maintenance ->
protein biosynthesis, ribosome biogenesis and assembly
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, MIG1
|YNR028W|CPR8peptidyl-prolyl cis-trans isomerase activity ->
peptidyl-prolyl cis-trans isomerase activity
ASH1, DIG1, MCM1
YDR134CNO SYMBOLASH1, NRG1, SOK2, SWI4
YGL225WVRG4nucleotide-sugar transport, N-linked glycosylation, lipid glycosylation ->
nucleotide-sugar transport, protein biosynthesis, lipid glycosylation, protein modification, glycoprotein metabolism
nucleotide-sugar transporter activity ->
nucleotide-sugar transporter activity
Golgi apparatus ->
cytoplasm
YNL082WPMS1mismatch repair, meiosis ->
DNA replication and chromosome cycle, M phase, DNA repair, mitotic cell cycle, DNA metabolism
ATPase activity, ATP binding, DNA binding ->
ATPase activity, ATP binding, DNA binding
nuclear chromosome ->
chromosome, nucleus
MTH1
Main:mitotic cell cycle (0.67)DNA binding (0.43)nucleus (0.50)SWI4 (0.50)
Score:0.470.140.270.286
P-value:5.091E-02 (DNA replication)1.637E-01 (DNA binding)4.464E+00 (nucleus)9.947E-03 (SWI4)

CSRE(1) AND MCB(1) => SimExpr(YML027W) OR SimExpr(other) : 5 2

MCM1(1) AND MCB(1) => SimExpr(YML027W) OR SimExpr(other) : 7 2

    EXPR: (0.191) MCB (P < 0.080) MCM1 (P < 0.000)

ORFSYMBOLPFCTF
YML027WYOX1negative regulation of transcription from Pol II promoter\, mitotic, regulation of mitotic cell cycle ->
regulation of transcription, M phase, transcription, cell cycle
specific transcriptional repressor activity, DNA binding ->
specific transcriptional repressor activity, DNA binding
nucleus ->
nucleus
MBP1, SWI4, SWI6
YGR189CCRH1cell wall, incipient bud site ->
cell wall, incipient bud site
GRF10(Pho2), MBP1, RLM1, STE12, SWI4, SWI5
YGL163CRAD54double-strand break repair via synthesis-dependent strand annealing, heteroduplex formation, double-strand break repair via break-induced replication, telomerase-independent telomere maintenance, double-strand break repair via single-strand annealing, chromatin modeling ->
mating-type switching/recombination, chromosome organization and biogenesis (sensu Eukarya), DNA repair, response to DNA damage, DNA metabolism
DNA supercoiling activity, DNA dependent ATPase activity ->
DNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides
nucleus ->
nucleus
|YIL066C|RNR3DNA replication ->
cell cycle, DNA metabolism
ribonucleoside-diphosphate reductase activity ->
oxidoreductase activity\, acting on CH2 groups
cytoplasm ->
cytoplasm
RFX1, STB1
YGR109CCLB6regulation of CDK activity, G1/S transition of mitotic cell cycle, premeiotic DNA synthesis ->
cell cycle, mitotic cell cycle, DNA metabolism
cyclin-dependent protein kinase\, regulator activity ->
transferase activity\, transferring phosphorus-containing groups, protein kinase regulator activity
MBP1, STB1, SWI4, SWI6
YDR309CGIC2axial budding, Rho protein signal transduction, establishment of cell polarity (sensu Saccharomyces) ->
budding, intracellular signaling cascade, cytoplasm organization and biogenesis
small GTPase regulatory/interacting protein activity ->
small GTPase regulatory/interacting protein activity
actin cap (sensu Saccharomyces), bud tip, shmoo tip, incipient bud site ->
cell cortex, site of polarized growth (sensu Fungi), incipient bud site, cytoplasm
ASH1, HSF1, MBP1, PHD1, RLM1, SKN7, STB1, STE12, SWI4, SWI6
YKR077WNO SYMBOL
|YNR028W|CPR8peptidyl-prolyl cis-trans isomerase activity ->
cis-trans isomerase activity
ASH1, DIG1, MCM1
YDR279WRNH202GCR2, MBP1, RIM101, RLM1, SWI6, THI2
Main:DNA metabolism (0.60)DNA binding (0.33)cytoplasm (0.40)MBP1 (0.71)
Score:0.500.070.300.619
P-value:4.056E-01 (mitotic cell cycle)7.505E-01 (DNA binding)5.771E-03 (incipient bud site)5.451E-05 (MBP1)

RAP1(1) AND MCM1'(1) => SimExpr(YKL152C) OR SimExpr(other) : 18 2

CSRE(1) AND RAP1(1) => SimExpr(YKL152C) OR SimExpr(other) : 12 2

CSRE(1) AND RAP1(1) AND MCM1'(1) => SimExpr(YKL152C) : 9

RAP1(1) AND ALPHA1(1) AND MCM1'(1) => SimExpr(YKL152C) : 9

CSRE(1) AND RAP1(1) => SimExpr(YGR214W) OR SimExpr(other) : 12 2

RAP1(1) AND MCM1'(1) => SimExpr(YGR214W) OR SimExpr(other) : 18 2

CSRE(1) AND RAP1(1) AND MCM1'(1) => SimExpr(YGR214W) : 9

RAP1(1) AND ALPHA1'(1) AND MCM1'(1) => SimExpr(YGR214W) : 7

HAP234(1) AND MCM1'(1) => SimExpr(YNL069C) OR SimExpr(other) : 9 4

    EXPR: (0.212) MCM1' (P < 0.000) HAP234 (P < 0.074)

ORFSYMBOLPFCTF
YDL181WINH1ATP synthesis coupled proton transport ->
transport
proton-transporting ATP synthase complex (sensu Eukarya) ->
cytoplasm, proton-transporting ATP synthase complex, integral to membrane, inner membrane
HAP4
YLR304CACO1tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis, propionate metabolism ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis
aconitate hydratase activity ->
carbon-oxygen lyase activity
cytosol, mitochondrial matrix ->
cytoplasm
CIN5, YAP6
YNL069CRPL16Bprotein biosynthesis ->
biosynthesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, GAT3, PDR1, RAP1, RGM1, YAP5
|YPL177C|CUP9copper ion homeostasis, transcription initiation from Pol II promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, cell homeostasis, transcription
specific RNA polymerase II transcription factor activity ->
specific RNA polymerase II transcription factor activity
nucleus ->
nucleus
BAS1, CIN5, MAC1, PHD1, SWI4, YAP6
|YJL079C|PRY1nuclear membrane, endoplasmic reticulum ->
nucleus, cytoplasm, endomembrane system
NDD1, PHD1, RAP1
YDL137WARF2ER to Golgi transport, intra-Golgi transport ->
transport, vesicle-mediated transport
ARF small monomeric GTPase activity ->
purine nucleotide binding, hydrolase activity\, acting on acid anhydrides
Golgi vesicle, cytosol ->
cytoplasm, Golgi apparatus
MSS11, REB1, RGT1, SIG1, SKN7, SOK2
YMR143WRPS16Aprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex
FHL1, GAT3, RAP1, RGM1, YAP5
YPR035WGLN1nitrogen metabolism, glutamine biosynthesis ->
nitrogen metabolism, amine metabolism, amino acid and derivative metabolism, organic acid metabolism, biosynthesis
glutamate-ammonia ligase activity ->
ligase activity\, forming carbon-nitrogen bonds
cytoplasm ->
cytoplasm
CIN5, DAL81, FKH1, FKH2, GLN3, HSF1, INO4, MSN1, REB1, SWI4
|YNL040W|NO SYMBOLFZF1, GCR2, RTG3, YAP7
|YKL198C|PTK1polyamine transport ->
transport
protein kinase activity ->
transferase activity\, transferring phosphorus-containing groups
INO2
YDR377WATP17ATP synthesis coupled proton transport ->
transport
hydrogen-transporting ATP synthase activity ->
cation transporter activity
proton-transporting ATP synthase complex\, coupling factor F(o) (sensu Eukarya) ->
cytoplasm, proton-transporting ATP synthase complex, integral to membrane, inner membrane
ARO80, HAP2, HAP3, HAP4, RPH1
YFR033CQCR6aerobic respiration, oxidative phosphorylation\, ubiquinone to cytochrome c ->
energy pathways, electron transport, phosphorus metabolism
ubiquinol-cytochrome c reductase activity ->
oxidoreductase activity\, acting on diphenols and related substances as donors, primary active transporter activity, cation transporter activity
mitochondrion, respiratory chain complex III (sensu Eukarya) ->
cytoplasm, respiratory chain complex III, inner membrane
HAP4, MBP1
YDL140CRPO21transcription from Pol II promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
DNA-directed RNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups
DNA-directed RNA polymerase II\, core complex ->
nucleus
REB1
Main:biosynthesis (0.36)structural constituent of ribosome (0.20)cytoplasm (0.82)REB1 HAP4 RAP1 CIN5 (0.23)
Score:0.250.070.710.167
P-value:4.375E-02 (ATP synthesis coupled proton transport)1.008E-01 (hydrogen ion transporter activity)3.537E-02 (proton-transporting ATP synthase complex)2.498E-02 (HAP4)

CSRE(1) AND RAP1(1) => SimExpr(YNL069C) OR SimExpr(other) : 12 2

CSRE(1) AND HAP234(1) => SimExpr(YNL069C) : 6

CSRE(1) AND RAP1(1) AND MCM1'(1) => SimExpr(YNL069C) : 9

RAP1(1) AND MCM1'(1) => SimExpr(YLR344W) OR SimExpr(other) : 19 1

RAP1(1) AND SWI5(1) => SimExpr(YLR344W) OR SimExpr(other) : 16 7

    EXPR: (0.218) SWI5 (P < 0.000) RAP1 (P < 0.150)

ORFSYMBOLPFCTF
|YNL311C|NO SYMBOLGCN4, RAP1
|YMR224C|MRE11DNA repair, double-strand break repair via nonhomologous end-joining, meiotic DNA double-strand break formation, meiotic DNA double-strand break processing, double-strand break repair via break-induced replication ->
DNA metabolism, cell proliferation, catabolism
endonuclease activity, 3'-5' exonuclease activity, protein binding ->
nuclease activity, protein binding
nucleus ->
nucleus
RAP1
YLR452CSST2signal transduction, adaptation to pheromone during conjugation with cellular fusion ->
signal transduction, conjugation, perception of external stimulus, sexual reproduction, response to abiotic stimulus
GTPase activator activity ->
GTPase activator activity
plasma membrane ->
membrane
DIG1, FHL1, RAP1, STE12
YNL069CRPL16Bprotein biosynthesis ->
biosynthesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, GAT3, PDR1, RAP1, RGM1, YAP5
YJR145CRPS4Aprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya), cytoplasm ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex
ACE2, CIN5, FHL1, INO4, MTH1, RAP1, YAP6
YGL030WRPL30protein biosynthesis, rRNA processing, mRNA splicing, regulation of translation ->
cell organization and biogenesis, biosynthesis, transcription, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya), cytoplasm ->
cytoplasm, ribonucleoprotein complex
FHL1, GAT3, RAP1, SFP1
|YGL196W|NO SYMBOL
YDR450WRPS18Aprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex
FHL1, GAT3, HIR2, RAP1, RGM1, YAP5
|YJL217W|NO SYMBOLCIN5, MAC1, PHD1, SWI5, YAP6
YMR194WRPL36Aprotein biosynthesis ->
biosynthesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
ARG80, ARO80, BAS1, CUP9, FHL1, HAL9, HAP4, HAP5, HMS1, MET31, NRG1, RAP1, RCS1, RME1, STP2
YLR441CRPS1Aprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex
FHL1, GAT3, RAP1, YAP5
YPR080WTEF1translational elongation ->
biosynthesis, protein metabolism
translation elongation factor activity ->
translation elongation factor activity
ribosome ->
cytoplasm, ribonucleoprotein complex
FHL1, PDR1, RAP1, YAP5
YOR312CRPL20Bprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, FKH2, GAT3, RAP1
YLR249WYEF3translational elongation ->
biosynthesis, protein metabolism
translation elongation factor activity ->
translation elongation factor activity
ribosome ->
cytoplasm, ribonucleoprotein complex
INO2, INO4
|YKR092C|SRP40nucleocytoplasmic transport ->
transport
chaperone activity ->
chaperone activity
nucleolus ->
nucleus
CUP9, MET4, RAP1
YKL006WRPL14Aprotein biosynthesis ->
biosynthesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, GAT3, GRF10(Pho2), GTS1, RAP1
|YPR161C|SGV1transcription, protein amino acid phosphorylation ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, phosphorus metabolism, protein metabolism
cyclin-dependent protein kinase activity ->
phosphotransferase activity\, alcohol group as acceptor
nucleus ->
nucleus
RAP1
|YOR213C|SAS5chromatin silencing at telomere ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription
acetyltransferase activity ->
transferase activity\, transferring groups other than amino-acyl groups
nuclear chromosome\, telomeric region, nuclear chromatin ->
chromosome, nuclear chromosome
GRF10(Pho2), SUM1
YOR369CRPS12protein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex
ARG80, FHL1, FKH2, LEU3, NDD1, PDR1, RME1, SMP1, YAP6
YMR013CSEC59protein-ER targeting, protein amino acid glycosylation ->
cell organization and biogenesis, biosynthesis, protein modification, protein metabolism, transport
dolichol kinase activity ->
phosphotransferase activity\, alcohol group as acceptor
membrane ->
membrane
FHL1, NDD1, RAP1, RLM1, RME1
YGL115WSNF4regulation of transcription from Pol II promoter, peroxisome organization and biogenesis ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
protein kinase activator activity ->
protein kinase activator activity
plasma membrane, nucleus, cytoplasm ->
membrane, nucleus, cytoplasm
BAS1, CAD1, MAC1, NRG1, PDR1, RAP1, SMP1, YAP5
YOL120CRPL18Aprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, MAL13, RAP1, YAP5
YLR344WRPL26Aprotein biosynthesis ->
biosynthesis, protein metabolism
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, RAP1
Main:protein metabolism (0.75)structural constituent of ribosome (0.55)cytoplasm (0.70)RAP1 (0.82)
Score:0.590.300.530.745
P-value:3.851E-07 (protein biosynthesis)3.734E-07 (structural constituent of ribosome)1.306E-08 (cytosolic ribosome (sensu Eukarya))4.765E-17 (RAP1)

CSRE(1) AND RAP1(1) => SimExpr(YLR344W) OR SimExpr(other) : 12 2

RAP1(1) AND SWI5(1) AND SCB(1) => SimExpr(YLR344W) : 5

    EXPR: (0.146) SWI5 (P < 0.000) SCB (P < 0.000) RAP1 (P < 0.003)

ORFSYMBOLPFCTF
YMR194WRPL36Aprotein biosynthesis ->
protein biosynthesis
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
ARG80, ARO80, BAS1, CUP9, FHL1, HAL9, HAP4, HAP5, HMS1, MET31, NRG1, RAP1, RCS1, RME1, STP2
YPR080WTEF1translational elongation ->
protein biosynthesis
translation elongation factor activity ->
translation elongation factor activity
ribosome ->
ribosome
FHL1, PDR1, RAP1, YAP5
YLR249WYEF3translational elongation ->
protein biosynthesis
translation elongation factor activity ->
translation elongation factor activity
ribosome ->
ribosome
INO2, INO4
YOR369CRPS12protein biosynthesis ->
protein biosynthesis
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
cytosol, eukaryotic 43S pre-initiation complex, eukaryotic 48S initiation complex, ribosome
ARG80, FHL1, FKH2, LEU3, NDD1, PDR1, RME1, SMP1, YAP6
YLR344WRPL26Aprotein biosynthesis ->
protein biosynthesis
RNA binding, structural constituent of ribosome ->
RNA binding, structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytosol, ribosome
FHL1, RAP1
Main:protein biosynthesis (1.00)structural constituent of ribosome (0.60)ribosome (1.00)FHL1 (0.80)
Score:1.000.401.000.600
P-value:1.836E-04 (protein biosynthesis)1.741E-03 (translation elongation factor activity)3.393E-05 (ribosome)9.347E-05 (FHL1)

RAP1(1) AND SWI5(1) AND MCM1'(1) => SimExpr(YLR344W) : 7

RAP1(1) AND ALPHA1'(1) AND MCM1'(1) => SimExpr(YLR344W) : 7

CSRE(1) AND RAP1(1) AND MCM1'(1) => SimExpr(YLR344W) : 9

SFF(1) AND mRRPE(1) AND ECB(1) => SimExpr(YML058W) OR SimExpr(other) : 7 2

    EXPR: (0.220) SFF (P < 0.000) mRRPE (P < 0.000) ECB (P < 0.002)

ORFSYMBOLPFCTF
YLR333CRPS25Bprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex
FHL1, RAP1
YOR315WNO SYMBOLACE2, CIN5, CUP9, FKH2, IXR1, MCM1, NDD1, NRG1, RLM1, ROX1, SKN7, SUM1, SWI4, SWI6, YAP1, YAP6
YDL140CRPO21transcription from Pol II promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
DNA-directed RNA polymerase activity ->
nucleotidyltransferase activity
DNA-directed RNA polymerase II\, core complex ->
nucleus
REB1
YNR053CNOG2mRNA splicing ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
GTPase activity ->
guanyl nucleotide binding, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides
nucleus, nucleolus, nucleoplasm ->
nucleus, nucleoplasm
ABF1, AZF1
YLR328WNMA1nicotinamide adenine dinucleotide metabolism ->
coenzymes and prosthetic group metabolism, vitamin metabolism
nicotinamide-nucleotide adenylyltransferase activity ->
nucleotidyltransferase activity
CIN5, MSN1, ROX1
|YOR066W|NO SYMBOLMBP1, MCM1
|YPL128C|TBF1loss of chromatin silencing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription
DNA binding, transcription factor activity ->
DNA binding, transcription factor activity
nuclear chromosome\, telomeric region, nuclear chromosome, nucleus ->
chromosome, nucleus
YML058WSML1response to DNA damage, mitochondrion organization and biogenesis ->
response to biotic stimulus, cell organization and biogenesis
enzyme inhibitor activity ->
enzyme inhibitor activity
NDD1, RFX1, SWI6
YJL159WHSP150cell wall organization and biogenesis ->
cell organization and biogenesis
structural constituent of cell wall ->
structural constituent of cell wall
cell wall ->
cell wall
ACE2, HIR2, MCM1, RLM1, SWI5
Main:cell organization and biogenesis (0.43)nucleotidyltransferase activity (0.29)nucleus (0.60)MCM1 (0.38)
Score:0.290.050.300.179
P-value:2.826E+00 (transcription\, DNA-dependent)8.582E-02 (nucleotidyltransferase activity)7.322E-01 (nucleoplasm)7.098E-02 (MCM1)

ALPHA1'(1) AND SFF(1) AND mRRPE(1) AND ECB(1) => SimExpr(YML058W) : 6

    EXPR: (0.182) ALPHA1' (P < 0.000) SFF (P < 0.000) mRRPE (P < 0.000) ECB (P < 0.000)

ORFSYMBOLPFCTF
YLR333CRPS25Bprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
cytosolic small ribosomal subunit (sensu Eukarya)
FHL1, RAP1
YOR315WNO SYMBOLACE2, CIN5, CUP9, FKH2, IXR1, MCM1, NDD1, NRG1, RLM1, ROX1, SKN7, SUM1, SWI4, SWI6, YAP1, YAP6
YNR053CNOG2mRNA splicing ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
GTPase activity ->
GTPase activity
nucleus, nucleolus, nucleoplasm ->
nucleus, nucleolus, nucleoplasm
ABF1, AZF1
YLR328WNMA1nicotinamide adenine dinucleotide metabolism ->
coenzymes and prosthetic group metabolism, vitamin metabolism
nicotinamide-nucleotide adenylyltransferase activity ->
nicotinamide-nucleotide adenylyltransferase activity
CIN5, MSN1, ROX1
YML058WSML1response to DNA damage, mitochondrion organization and biogenesis ->
response to biotic stimulus, cell organization and biogenesis
enzyme inhibitor activity ->
enzyme inhibitor activity
NDD1, RFX1, SWI6
YJL159WHSP150cell wall organization and biogenesis ->
cell organization and biogenesis
structural constituent of cell wall ->
structural constituent of cell wall
cell wall ->
cell wall
ACE2, HIR2, MCM1, RLM1, SWI5
Main:cell organization and biogenesis (0.40)structural constituent of cell wall (0.20)nucleolus (0.33)RLM1 ACE2 SWI6 CIN5 NDD1 ROX1 MCM1 (0.33)
Score:0.100.000.000.200
P-value:3.811E+00 (cell organization and biogenesis)5.051E-01 (structural molecule activity)3.999E+00 (intracellular)6.777E-02 (ACE2)

BAS1(1) AND MCB(1) => SimExpr(YGR109C) OR SimExpr(other) : 5 1

    EXPR: (0.169) BAS1 (P < 0.000) MCB (P < 0.034)

ORFSYMBOLPFCTF
|YIL066C|RNR3DNA replication ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
ribonucleoside-diphosphate reductase activity ->
ribonucleoside-diphosphate reductase activity
cytoplasm ->
cytoplasm
RFX1, STB1
YGR109CCLB6regulation of CDK activity, G1/S transition of mitotic cell cycle, premeiotic DNA synthesis ->
cell proliferation, cell cycle, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
cyclin-dependent protein kinase\, regulator activity ->
cyclin-dependent protein kinase\, regulator activity
MBP1, STB1, SWI4, SWI6
YJR154WNO SYMBOLCIN5, GCN4, RIM101
YHR110WERP5secretory pathway ->
transport
integral to membrane ->
integral to membrane
DOT6, RGT1
YJL181WNO SYMBOL
YPR185WAPG13protein-vacuolar targeting, autophagy ->
cell organization and biogenesis, autophagy, protein metabolism, transport
protein binding ->
protein binding
extrinsic to membrane ->
extrinsic to membrane
MET4, SWI6
Main:cell proliferation (0.50)cyclin-dependent protein kinase\, regulator activity (0.33)extrinsic to membrane (0.33)SWI6 STB1 (0.40)
Score:0.330.000.000.200
P-value:1.640E-01 (DNA replication)2.725E+00 (enzyme activity)1.666E+00 (membrane)2.568E-02 (STB1)

MCM1(1) AND MCB(1) => SimExpr(YKR077W) OR SimExpr(other) : 6 3

SFF(1) AND mRRPE(1) AND MCB(1) => SimExpr(YDR279W) OR SimExpr(other) : 5 2

    EXPR: (0.205) SFF (P < 0.000) mRRPE (P < 0.000) MCB (P < 0.038)

ORFSYMBOLPFCTF
|YOR033C|EXO1mismatch repair ->
DNA replication and chromosome cycle, DNA repair, mitotic cell cycle, DNA metabolism
exonuclease activity, flap endonuclease activity, 5'-3' exonuclease activity ->
DNA binding, nuclease activity
nucleus ->
nucleus
RGT1
YFR031CSMC2mitotic chromosome condensation, mitotic chromosome segregation ->
DNA replication and chromosome cycle, M phase of mitotic cell cycle, M phase
DNA secondary structure binding, AT DNA binding, double-stranded DNA binding, ATPase activity ->
DNA binding, double-stranded DNA binding, purine nucleotide binding, hydrolase activity\, acting on acid anhydrides
nuclear condensin complex ->
chromosome, nucleus
INO2, MET4
YMR279CNO SYMBOLIXR1, MIG1, MTH1, RFX1, SWI4, SWI6
YNL102WPOL1DNA replication\, priming, DNA replication initiation, lagging strand elongation, DNA repair synthesis ->
DNA replication and chromosome cycle, mitotic recombination, mitotic cell cycle, DNA metabolism, DNA repair
alpha DNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups
alpha DNA polymerase\:primase complex ->
nucleus
LEU3, MBP1
|YDR093W|DNF2intracellular protein transport ->
intracellular protein transport
phospholipid-translocating ATPase activity ->
phospholipid binding, purine nucleotide binding, primary active transporter activity, cation transporter activity, hydrolase activity\, acting on acid anhydrides
plasma membrane ->
plasma membrane
GTS1
YDR279WRNH202GCR2, MBP1, RIM101, RLM1, SWI6, THI2
YJR001WAVT1neutral amino acid transport ->
amine/polyamine transport, carboxylic acid transport
neutral amino acid transporter activity ->
carboxylic acid transporter activity
vacuole ->
cytoplasm
CRZ1, GAT3, MATa1
Main:DNA replication and chromosome cycle (0.60)DNA binding (0.40)nucleus (0.60)MBP1 SWI6 (0.29)
Score:0.300.200.300.095
P-value:1.005E-01 (DNA replication and chromosome cycle)6.142E-01 (ATPase activity)2.364E+00 (nucleus)3.407E-01 (SWI6)

MCM1(1) AND PDR(1) => SimExpr(YOR273C) OR SimExpr(other) : 8 3

    EXPR: (0.234) PDR (P < 0.009) MCM1 (P < 0.014)

ORFSYMBOLPFCTF
YOR273CTPO4polyamine transport ->
transport
spermine transporter activity, spermidine transporter activity ->
spermine transporter activity, spermidine transporter activity
plasma membrane, vacuolar membrane ->
plasma membrane, cytoplasm
ARO80, BAS1, FZF1, HIR1, IME4, NRG1, PDR1, PHO4, SFP1, SKN7, STP1
YLR304CACO1tricarboxylic acid cycle, citrate metabolism, glutamate biosynthesis, propionate metabolism ->
carbohydrate metabolism, amine metabolism, organic acid metabolism, energy pathways, amino acid and derivative metabolism, biosynthesis
aconitate hydratase activity ->
aconitate hydratase activity
cytosol, mitochondrial matrix ->
cytoplasm
CIN5, YAP6
YKR042WUTH1mitochondrion organization and biogenesis ->
cell organization and biogenesis
cell wall, mitochondrial outer membrane ->
cell wall, cytoplasm, outer membrane
ACE2, ASH1, DAL81, FKH2, HSF1, MCM1, NDD1, SKN7, STE12, SWI4
|YFR022W|NO SYMBOL
YML116WATR1multidrug transport ->
transport, response to abiotic stimulus
multidrug efflux pump activity ->
multidrug efflux pump activity
plasma membrane ->
plasma membrane
CAD1, CIN5, FKH2, HSF1, PHD1, YAP1, YAP6
YJL082WIML2
YMR291WNO SYMBOLRAP1
|YNL289W|PCL1cell cycle ->
cell proliferation
cyclin-dependent protein kinase\, regulator activity ->
cyclin-dependent protein kinase\, regulator activity
cyclin-dependent protein kinase holoenzyme complex ->
cyclin-dependent protein kinase holoenzyme complex
ASH1, MBP1, MCM1, STB1, STE12, SWI4, SWI6
YKL163WPIR3cell wall organization and biogenesis ->
cell organization and biogenesis
structural constituent of cell wall ->
structural constituent of cell wall
cell wall ->
cell wall
MCM1, SMP1, SWI5
|YOL011W|PLB3phosphoinositide metabolism, phosphatidylserine catabolism ->
catabolism, lipid metabolism
lysophospholipase activity ->
lysophospholipase activity
extracellular space, plasma membrane ->
extracellular space, plasma membrane
SWI4
YML058WSML1response to DNA damage, mitochondrion organization and biogenesis ->
response to biotic stimulus, cell organization and biogenesis
enzyme inhibitor activity ->
enzyme inhibitor activity
NDD1, RFX1, SWI6
Main:cell organization and biogenesis (0.38)structural constituent of cell wall (0.14)cytoplasm (0.43)SWI4 MCM1 (0.33)
Score:0.140.000.330.278
P-value:3.512E-01 (mitochondrion organization and biogenesis)3.385E-01 (enzyme regulator activity)2.965E-01 (plasma membrane)1.558E-01 (ASH1)

RAP1(1) AND MCM1'(1) => SimExpr(YGR085C) OR SimExpr(other) : 18 2

RAP1(1) AND ALPHA1(1) AND MCM1'(1) => SimExpr(YGR085C) : 9

HAP234(1) AND MCM1'(1) => SimExpr(YMR143W) OR SimExpr(other) : 9 4

RAP1(1) AND SWI5(1) AND SCB(1) => SimExpr(YMR194W) : 5

RAP1(1) AND MCM1'(1) => SimExpr(YMR142C) OR SimExpr(other) : 18 2

RAP1(1) AND ALPHA1(1) AND MCM1'(1) => SimExpr(YMR142C) : 9

RAP1(1) AND ALPHA1'(1) AND MCM1'(1) => SimExpr(YMR142C) : 7

RAP1(1) AND mRRPE(1) => SimExpr(YMR116C) OR SimExpr(other) : 7 3

RAP1(1) AND SWI5(1) AND SCB(1) => SimExpr(YOR369C) : 5

RAP1(1) AND mRRPE(1) => SimExpr(YDL130W) OR SimExpr(other) : 7 3

RAP1(1) AND MCM1'(1) => SimExpr(YDL130W) OR SimExpr(other) : 18 2

RAP1(1) AND ALPHA1'(1) AND MCM1'(1) => SimExpr(YDL130W) : 7

RAP1(1) AND ALPHA1(1) AND MCM1'(1) => SimExpr(YDL130W) : 9

RAP1(1) AND PDR(1) => SimExpr(YML026C) OR SimExpr(other) : 5 1

    EXPR: (0.161) PDR (P < 0.000) RAP1 (P < 0.122)

ORFSYMBOLPFCTF
YML026CRPS18Bprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex
FHL1, GAT3, RAP1, RGM1, SWI4, YAP5
YLR441CRPS1Aprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex
FHL1, GAT3, RAP1, YAP5
YGR254WENO1gluconeogenesis, glycolysis ->
alcohol metabolism, carbohydrate biosynthesis, carbohydrate metabolism, energy derivation by oxidation of organic compounds, biosynthesis, catabolism
phosphopyruvate hydratase activity ->
phosphopyruvate hydratase activity
phosphopyruvate hydratase complex, cytoplasm ->
cytoplasm
FKH2, MSN4, PDR1, SWI5, YAP5
YPR080WTEF1translational elongation ->
biosynthesis, protein metabolism
translation elongation factor activity ->
translation elongation factor activity
ribosome ->
cytoplasm, ribonucleoprotein complex
FHL1, PDR1, RAP1, YAP5
YNL096CRPS7Bprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex
FHL1, GAT3, RAP1, SFP1
|YOR213C|SAS5chromatin silencing at telomere ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription
acetyltransferase activity ->
acetyltransferase activity
nuclear chromosome\, telomeric region, nuclear chromatin ->
chromosome, nuclear chromosome
GRF10(Pho2), SUM1
Main:biosynthesis (0.83)structural constituent of ribosome (0.50)cytoplasm (0.83)FHL1 RAP1 YAP5 (0.67)
Score:0.670.200.670.600
P-value:1.770E-02 (biosynthesis)2.066E-02 (structural constituent of ribosome)1.614E-03 (cytosolic small ribosomal subunit (sensu Eukarya))1.154E-05 (YAP5)

RAP1(1) AND mRRPE(1) => SimExpr(YGL030W) OR SimExpr(other) : 7 3

RAP1(1) AND MCM1'(1) => SimExpr(YJR139C) OR SimExpr(other) : 18 2

RAP1(1) AND ALPHA2(1) => SimExpr(YJR139C) OR SimExpr(other) : 5 2

    EXPR: (0.223) ALPHA2 (P < 0.000) RAP1 (P < 0.061)

ORFSYMBOLPFCTF
YMR142CRPL13Bprotein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic large ribosomal subunit (sensu Eukarya) ->
cytoplasm, ribonucleoprotein complex
FHL1, GAT3, RAP1, RGM1, YAP5
YLR249WYEF3translational elongation ->
biosynthesis, protein metabolism
translation elongation factor activity ->
translation elongation factor activity
ribosome ->
cytoplasm, ribonucleoprotein complex
INO2, INO4
YJR139CHOM6homoserine biosynthesis, methionine metabolism, threonine metabolism ->
amine metabolism, sulfur metabolism, biosynthesis, amino acid and derivative metabolism, organic acid metabolism
homoserine dehydrogenase activity ->
homoserine dehydrogenase activity
HMS1, RAP1
YOR369CRPS12protein biosynthesis ->
biosynthesis, protein metabolism
structural constituent of ribosome ->
structural constituent of ribosome
cytosolic small ribosomal subunit (sensu Eukarya) ->
eukaryotic 48S initiation complex, cytoplasm, ribonucleoprotein complex
ARG80, FHL1, FKH2, LEU3, NDD1, PDR1, RME1, SMP1, YAP6
|YPL162C|NO SYMBOL
|YDL043C|PRP11spliceosome assembly ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
RNA binding ->
RNA binding
snRNP U2 ->
nucleus, ribonucleoprotein complex
DAL81, STP1
YNL311CNO SYMBOLGCN4, RAP1
Main:biosynthesis (0.80)structural constituent of ribosome (0.40)ribonucleoprotein complex (1.00)RAP1 (0.50)
Score:0.600.101.000.267
P-value:3.052E-01 (protein biosynthesis)3.977E-01 (structural constituent of ribosome)3.008E-02 (ribonucleoprotein complex)1.209E-01 (RAP1)

RAP1(1) AND ALPHA1(1) AND MCM1'(1) => SimExpr(YJR139C) : 9

RAP1(1) AND MCM1'(1) => SimExpr(YKL006W) OR SimExpr(other) : 18 2

RAP1(1) AND ALPHA1(1) AND MCM1'(1) => SimExpr(YKL006W) : 9

RAP1(1) AND PDR(1) => SimExpr(YLR441C) OR SimExpr(other) : 5 1

RAP1(1) AND MCM1'(1) => SimExpr(YIL018W) OR SimExpr(other) : 18 2

RAP1(1) AND ALPHA1(1) AND MCM1'(1) => SimExpr(YIL018W) : 9

RAP1(1) AND mRRPE(1) => SimExpr(YLR249W) OR SimExpr(other) : 7 3

RAP1(1) AND ALPHA1(1) AND SFF(1) => SimExpr(YLR249W) OR SimExpr(other) : 12 5

RAP1(1) AND SWI5(1) AND SCB(1) => SimExpr(YLR249W) : 5

RAP1(1) AND PDR(1) => SimExpr(YNL096C) OR SimExpr(other) : 5 1

RAP1(1) AND mRRPE(1) => SimExpr(YPR080W) OR SimExpr(other) : 7 3

RAP1(1) AND SWI5(1) AND SCB(1) => SimExpr(YPR080W) : 5

ndt80(MSE)(1) AND mRRPE(1) => SimExpr(YFR023W) OR SimExpr(other) : 5 2

    EXPR: (0.195) ndt80(MSE) (P < 0.025) mRRPE (P < 0.001)

ORFSYMBOLPFCTF
YHR184WSSP1spore wall assembly (sensu Saccharomyces), protein complex assembly ->
protein metabolism, sporulation
prospore membrane ->
prospore
SUM1
YOR338WNO SYMBOLRAP1
YOL091WSPO21spore wall assembly (sensu Saccharomyces), meiosis ->
cell proliferation, sporulation
structural molecule activity ->
structural molecule activity
spindle pole body ->
cytoplasm
HAP5, SUM1
YOR339CUBC11protein polyubiquitination, protein monoubiquitination ->
catabolism, protein metabolism
ubiquitin conjugating enzyme activity ->
ubiquitin conjugating enzyme activity
cytoplasm ->
cytoplasm
HAP2, IXR1
|YGL253W|HXK2fructose metabolism ->
alcohol metabolism, carbohydrate metabolism
hexokinase activity ->
hexokinase activity
nucleus, cytosol ->
nucleus, cytoplasm
ABF1, CIN5, HSF1, SWI4
|YJR007W|SUI2translational initiation ->
biosynthesis, protein metabolism
translation initiation factor activity ->
translation initiation factor activity
ribosome, cytoplasm ->
cytoplasm, ribonucleoprotein complex
GLN3, HAP3, HIR1, RCS1
YFR023WPES4DNA dependent DNA replication ->
cell proliferation, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
DIG1, FKH1, FKH2, GLN3, HAP3, MCM1, MSN2, RIM101, RLM1, RTG3, STE12, SUM1, THI2, YAP1
Main:protein metabolism (0.50)ubiquitin conjugating enzyme activity (0.25)cytoplasm (0.80)SUM1 (0.43)
Score:0.330.000.600.190
P-value:1.686E-02 (spore wall assembly (sensu Saccharomyces))2.849E+00 (enzyme activity)3.294E+00 (cytoplasm)4.371E-03 (SUM1)

ALPHA1(1) AND ALPHA2(1) AND MCB(1) => SimExpr(YOR144C) OR SimExpr(other) : 5 2

    EXPR: (0.191) ALPHA2 (P < 0.000) MCB (P < 0.066) ALPHA1 (P < 0.000)

ORFSYMBOLPFCTF
|YPL140C|MKK2protein amino acid phosphorylation, signal transduction ->
phosphate metabolism, signal transduction, protein modification
MAP kinase kinase activity ->
protein kinase activity
intracellular ->
intracellular
FKH1, FKH2
YNL082WPMS1mismatch repair, meiosis ->
DNA repair, cell cycle, DNA metabolism
ATPase activity, ATP binding, DNA binding ->
ATP binding, DNA binding, hydrolase activity\, acting on acid anhydrides\, in phosphorus-containing anhydrides
nuclear chromosome ->
intracellular
MTH1
YPR185WAPG13protein-vacuolar targeting, autophagy ->
cytoplasm organization and biogenesis, autophagy, intracellular transport, protein metabolism, protein transport
protein binding ->
protein binding
extrinsic to membrane ->
extrinsic to membrane
MET4, SWI6
|YJL095W|BCK1protein amino acid phosphorylation, protein kinase cascade, response to nutrients, establishment of cell polarity (sensu Saccharomyces) ->
phosphate metabolism, intracellular signaling cascade, response to extracellular stimulus, cytoplasm organization and biogenesis, protein modification, response to chemical substance
MAP kinase kinase kinase activity ->
protein kinase activity
intracellular ->
intracellular
YAP1
YFR027WECO1sister chromatid cohesion, DNA replication, DNA repair ->
DNA metabolism, cell cycle
acetyltransferase activity ->
acyltransferase activity
nuclear chromatin ->
intracellular
YOR284WHUA2RFX1, YAP6
YOR144CELG1negative regulation of DNA transposition, negative regulation of DNA recombination ->
DNA metabolism
YJL206C
Main:DNA metabolism (0.50)protein kinase activity (0.40)intracellular (0.80)YAP1 (0.17)
Score:0.330.100.600.000
P-value:3.096E-01 (protein amino acid phosphorylation)3.795E-01 (protein kinase activity)1.705E-01 (chromosome)7.321E-01 (YJL206C)

ALPHA1(1) AND ALPHA1'(1) AND SFF(1) AND AFT1(1) => SimExpr(YHL035C) OR SimExpr(other) : 6 2

    EXPR: (0.222) ALPHA1' (P < 0.000) SFF (P < 0.000) AFT1 (P < 0.001) ALPHA1 (P < 0.000)

ORFSYMBOLPFCTF
YMR083WADH3fermentation ->
fermentation
alcohol dehydrogenase activity ->
alcohol dehydrogenase activity
mitochondrial matrix, soluble fraction ->
mitochondrial matrix, soluble fraction
RAP1
|YOR389W|NO SYMBOLMCM1, YJL206C
YHL035CNO SYMBOLYFL044C
YMR253CNO SYMBOLMCM1
YMR088CNO SYMBOL
|YHR209W|NO SYMBOLLEU3
YOR381WFRE3iron-siderochrome transport, iron ion homeostasis ->
iron-siderochrome transport, iron ion homeostasis
ferric-chelate reductase activity ->
ferric-chelate reductase activity
plasma membrane, integral to membrane ->
plasma membrane, integral to membrane
CIN5, PDR1, YAP6
YKL167CMRP49protein biosynthesis ->
protein biosynthesis
structural constituent of ribosome ->
structural constituent of ribosome
mitochondrial large ribosomal subunit ->
mitochondrial matrix, large ribosomal subunit, organellar ribosome
ABF1, IME4, IXR1
Main:iron ion homeostasis (0.33)ferric-chelate reductase activity (0.33)mitochondrial matrix (0.67)MCM1 (0.29)
Score:0.000.000.330.048
P-value:3.993E+00 (metabolism)4.865E-01 (oxidoreductase activity)2.572E-01 (mitochondrial matrix)3.069E-01 (MCM1)

ABF1(1) AND SFF(1) AND PAC(1) => SimExpr(YKL014C) OR SimExpr(other) : 6 1

    EXPR: (0.194) ABF1 (P < 0.000) SFF (P < 0.000) PAC (P < 0.005)

ORFSYMBOLPFCTF
YKL078WDHR2ribosome biogenesis ->
cytoplasm organization and biogenesis
RNA helicase activity ->
RNA binding
nucleolus ->
nucleus
ABF1
YNL292WPUS4tRNA modification ->
RNA metabolism
pseudouridylate synthase activity ->
carbon-oxygen lyase activity
mitochondrion, nucleus ->
cytoplasm, nucleus
RCS1
|YGR283C|NO SYMBOLACE2, RAP1, SMP1
YGR187CHGH1ABF1, HAP3, HIR1, RCS1, RTG1
YKL014CNO SYMBOLABF1
YOL041CNOP12rRNA metabolism ->
RNA metabolism
RNA binding ->
RNA binding
nucleolus ->
nucleus
GTS1, MET31
YJL069CUTP18ABF1
Main:RNA metabolism (0.67)RNA binding (0.67)nucleus (1.00)ABF1 (0.57)
Score:0.330.331.000.333
P-value:5.684E-01 (RNA metabolism)6.158E-01 (RNA binding)1.881E-01 (nucleolus)6.557E-03 (ABF1)

ABF1(1) AND mRRPE(1) AND PAC(1) => SimExpr(YKL014C) OR SimExpr(other) : 8 2

    EXPR: (0.202) ABF1 (P < 0.000) mRRPE (P < 0.000) PAC (P < 0.003)

ORFSYMBOLPFCTF
YNL292WPUS4tRNA modification ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
pseudouridylate synthase activity ->
pseudouridylate synthase activity
mitochondrion, nucleus ->
cytoplasm, nucleus
RCS1
YPR010CRPA135transcription from Pol I promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
DNA-directed RNA polymerase activity ->
DNA-directed RNA polymerase activity
DNA-directed RNA polymerase I complex ->
nucleus
ROX1, SIG1
|YNR046W|NO SYMBOLABF1
YJL050WMTR435S primary transcript processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
ATP dependent RNA helicase activity ->
RNA helicase activity, ATP dependent helicase activity, RNA dependent ATPase activity
nucleolus ->
nucleus
YKL172WEBP2rRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
nucleolus ->
nucleus
ABF1, FZF1, RFX1
|YLR197W|SIK1rRNA modification, 35S primary transcript processing, processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, transcription
small nuclear ribonucleoprotein complex, small nucleolar ribonucleoprotein complex, nucleus, nucleolus ->
nucleus, ribonucleoprotein complex
DAL81, HAL9
YGR187CHGH1ABF1, HAP3, HIR1, RCS1, RTG1
YKL014CNO SYMBOLABF1
YNL112WDBP2RNA helicase activity ->
RNA helicase activity
bud neck ->
site of polarized growth (sensu Fungi)
YJL069CUTP18ABF1
Main:nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (1.00)RNA helicase activity (0.50)nucleus (0.83)ABF1 (0.62)
Score:1.000.170.670.393
P-value:5.515E-03 (transcription from Pol I promoter)4.187E-02 (RNA helicase activity)2.839E-03 (nucleolus)3.110E-03 (ABF1)

ABF1(1) AND ALPHA1'(1) AND PAC(1) => SimExpr(YKL014C) : 5

ABF1(1) AND SFF(1) AND PAC(1) => SimExpr(YGR187C) OR SimExpr(other) : 5 2

ABF1(1) AND ALPHA1'(1) AND PAC(1) => SimExpr(YOL041C) : 5

ABF1(1) AND SFF(1) AND PAC(1) => SimExpr(YNL292W) OR SimExpr(other) : 6 1

LYS14(1) AND mRRPE(1) AND MCM1'(1) => SimExpr(YML093W) OR SimExpr(other) : 6 2

    EXPR: (0.212) LYS14 (P < 0.000) mRRPE (P < 0.000) MCM1' (P < 0.000)

ORFSYMBOLPFCTF
|YNL042W|BOP3DAL82
YGR280CPXR135S primary transcript processing, snRNA processing ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
RNA binding ->
RNA binding
nucleolus ->
nucleus
YDL140CRPO21transcription from Pol II promoter ->
nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
DNA-directed RNA polymerase activity ->
transferase activity\, transferring phosphorus-containing groups
DNA-directed RNA polymerase II\, core complex ->
nucleus
REB1
YML093WUTP14processing of 20S pre-rRNA ->
cell organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
snoRNA binding ->
RNA binding
small nucleolar ribonucleoprotein complex ->
nucleus, ribonucleoprotein complex
YOL130WALR1di-\, tri-valent inorganic cation transport, magnesium ion transport ->
transport
di-\, tri-valent inorganic cation transporter activity ->
cation transporter activity
plasma membrane ->
plasma membrane
|YLR328W|NMA1nicotinamide adenine dinucleotide metabolism ->
coenzymes and prosthetic group metabolism, vitamin metabolism
nicotinamide-nucleotide adenylyltransferase activity ->
transferase activity\, transferring phosphorus-containing groups
CIN5, MSN1, ROX1
YDL088CASM4protein-nucleus import\, docking, mRNA-nucleus export, rRNA-nucleus export, snRNA-nucleus export, NLS-bearing substrate-nucleus import, snRNP protein-nucleus import, mRNA-binding (hnRNP) protein-nucleus import, ribosomal protein-nucleus import, protein-nucleus export, nuclear pore organization and biogenesis ->
intracellular transport, nuclear organization and biogenesis, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, protein metabolism, transport
structural molecule activity ->
structural molecule activity
nuclear pore ->
nucleus, integral to membrane, endomembrane system
YMR042WARG80positive regulation of transcription from Pol II promoter, arginine metabolism ->
amine metabolism, nitrogen metabolism, nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism, amino acid and derivative metabolism, organic acid metabolism
DNA binding, specific RNA polymerase II transcription factor activity ->
DNA binding, specific RNA polymerase II transcription factor activity
nucleus ->
nucleus
RME1
Main:nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism (0.71)RNA binding (0.29)nucleus (0.83)DAL82 (0.25)
Score:0.520.100.670.000
P-value:1.624E-01 (transcription\, DNA-dependent)7.594E-02 (nucleotidyltransferase activity)2.848E-01 (nucleolus)2.035E-01 (MSN1)

LYS14(1) AND mRRPE(1) AND PAC(1) => SimExpr(YML093W) OR SimExpr(other) : 6 2

LYS14(1) AND mRRPE(1) AND PAC(1) => SimExpr(YHR052W) OR SimExpr(other) : 7 1

AVERAGE SCORES:

P
  SCORE: 0.544 (Part of genes covered by "Main": 0.672) (No. rules=39/39)
  P-VALUE: 0.462
F
  SCORE: 0.181 (Part of genes covered by "Main": 0.418) (No. rules=39/39)
  P-VALUE: 0.308
C
  SCORE: 0.604 (Part of genes covered by "Main": 0.753) (No. rules=39/39)
  P-VALUE: 0.410
TF
  SCORE: 0.353 (Part of genes covered by "Main": 0.515) (No. rules=39/39)
  P-VALUE: 0.538
EXPRESSION: 0.718 (39)