Table 1 Annotation of known genes to
Gene Ontology biological process terms
Annotations
to Gene Ontology terms
Biological processes were assigned at the lowest possible (most specific) level of Gene Ontology (GO) (Ashburner M. et al, Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nature Genet., 25, 25-29 (2000)). Information for annotations was extracted manually from the databases Unigene (http://www.ncbi.nlm.nih.gov/UniGene/), SWISS-PROT (http://www.expasy.ch/sprot/sprot-top.html) and Genatlas (http://www.genatlas.org/) and from literature found in MedLine (http://www.ncbi.nlm.nih.gov/
|
GENE SYMBOL |
GENE NAME |
PROBE NO. (Iyer et.
al.) |
ACCESSION NUMBER |
ANNOTATIONS AT THE MOST SPECIFIC
LEVEL OF GO |
ANNOTATIONS TO THE 23 BROAD CELLULAR
PROCESSES USED FOR LEARNING |
|
SEPP1 |
selenoprotein P, plasma, 1 |
2 |
AA045003 |
oxidative stress
response(GO:0006979), metal ion transport(GO:0006823) |
stress
response(GO:0006950), transport(GO:0006810) |
|
EPB41L2 |
erythrocyte
membrane protein band 4.1-like 2 |
4 |
W88572 |
positive control of
cell proliferation(GO:0008284) |
cell
proliferation(GO:0008283) |
|
OA48-18 |
acid-inducible
phosphoprotein |
5 |
AA029909 |
cell
proliferation(GO:0008283) |
cell
proliferation(GO:0008283) |
|
CTSK |
cathepsin K
(pycnodysostosis) |
8 |
AA044619 |
proteolysis and
peptidolysis(GO:0006508) |
protein metabolism
and modification(GO:0006411) |
|
CPT1B |
carnitine palmitoyltransferase
I, muscle |
9 |
W89012 |
fatty acid
beta-oxidation(GO:0006635) |
lipid
metabolism(GO:0006629) |
|
CLDN11 |
claudin 11
(oligodendrocyte transmembrane protein) |
11 |
N22392 |
cell
adhesion(GO:0007155), substrate-bound cell migration(GO:0006929), cell
proliferation(GO:0008283), developmental processes(GO:0007275) |
cell
adhesion(GO:0007155), cell motility(GO:0006928), cell
proliferation(GO:0008283), developmental processes(GO:0007275) |
|
RPL5 |
ribosomal protein L5 |
12 |
AA027277 |
protein
biosynthesis(GO:0006412), ribosomal large subunit assembly and
maintenance(GO:0000027) |
protein metabolism
and modification(GO:0006411), cell organization and biogenesis(GO:0006996) |
|
|
Homo sapiens clone
23785 mRNA sequence |
14 |
N32247 |
calcium-independent
cell-cell matrix adhesion(GO:0007161) |
cell
adhesion(GO:0007155) |
|
|
ESTs, Weakly
similar to A45082 neurotrophic receptor ror1 precursor [H.sapiens] |
15 |
T62968 |
transmembrane
receptor protein tyrosine kinase signalling pathway(GO:0007169) |
cell surface
receptor linked signal transduction(GO:0007166) |
|
CCNG1 |
cyclin G1 |
19 |
R45687 |
cell cycle
control(GO:0000074), mitotic G2 phase(GO:0000085), apoptosis(GO:0006915),
mitosis(GO:0007067) |
cell
cycle(GO:0007049), cell death(GO:0008219) |
|
CDKN1C |
cyclin-dependent
kinase inhibitor 1C (p57, Kip2) |
21 |
R81336 |
cell cycle
arrest(GO:0007050), cell cycle arrest(GO:0007050), negative control of cell
proliferation(GO:0008285) |
cell
cycle(GO:0007049), cell proliferation(GO:0008283) |
|
GRIA1 |
glutamate receptor,
ionotropic, AMPA 1 |
22 |
N47974 |
induction of
apoptosis(GO:0006917), cell surface receptor linked signal
transduction(GO:0007166) |
cell
death(GO:0008219), cell surface receptor linked signal
transduction(GO:0007166) |
|
|
Homo sapiens mRNA for KIAA1888 protein, partial cds |
25 |
H26264 |
transport(GO:0006810) |
transport(GO:0006810) |
|
FMOD |
fibromodulin |
33 |
AA029408 |
cell-cell matrix
adhesion(GO:0007160) |
cell
adhesion(GO:0007155) |
|
CDK5R1 |
cyclin-dependent
kinase 5, regulatory subunit 1 (p35) |
36 |
R49183 |
cell
proliferation(GO:0008283), cell cycle control(GO:0000074) |
cell
proliferation(GO:0008283), cell cycle(GO:0007049) |
|
CAT |
catalase |
37 |
W89002 |
oxidative stress
response(GO:0006979), peroxidase reaction(GO:0006804) |
stress
response(GO:0006950) |
|
|
Homo sapiens, clone
MGC:16131 IMAGE:3628944, mRNA, complete cds |
47 |
R71462 |
transport(GO:0006810),
intracellular signalling cascade(GO:0007242) |
transport(GO:0006810),
intracellular signalling cascade(GO:0007242) |
|
|
ESTs, Moderately
similar to JX0336 succinate dehydrogenase [H.sapiens] |
48 |
R60996 |
tricarboxylic acid
cycle(GO:0006099), fatty acid metabolism(GO:0006631) |
energy
pathways(GO:0006091), lipid metabolism(GO:0006629) |
|
GBAS |
glioblastoma
amplified sequence |
50 |
T90846 |
cell surface
receptor linked signal transduction(GO:0007166) |
cell surface
receptor linked signal transduction(GO:0007166) |
|
MME |
membrane
metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10) |
53 |
H65598 |
proteolysis and
peptidolysis(GO:0006508), positive control of cell proliferation(GO:0008284),
defense (immune) response(GO:0006952), chemotaxis(GO:0006935),
substrate-bound cell migration, cell release from substrate(GO:0006933) |
protein metabolism
and modification(GO:0006411), cell proliferation(GO:0008283), defense
(immune) response(GO:0006952), cell motility(GO:0006928) |
|
DPP4 |
dipeptidylpeptidase
IV (CD26, adenosine deaminase complexing protein 2) |
55 |
H61694 |
substrate-bound
cell migration, cell release from substrate(GO:0006933),
digestion(GO:0007586), proteolysis and peptidolysis(GO:0006508) |
cell
motility(GO:0006928), protein metabolism and modification(GO:0006411) |
|
FBN2 |
fibrillin 2 (congenital
contractural arachnodactyly) |
59 |
AA025721 |
substrate-bound
cell migration(GO:0006929), cell-cell matrix adhesion(GO:0007160) |
cell
motility(GO:0006928), cell adhesion(GO:0007155) |
|
|
Homo sapiens cDNA:
FLJ23176 fis, clone LNG10452 |
60 |
AA034939 |
histogenesis and
organogenesis(GO:0007397), cell-cell matrix adhesion(GO:0007160) |
developmental
processes(GO:0007275), cell adhesion(GO:0007155) |
|
ANXA3 |
annexin A3 |
61 |
W45327 |
blood coagulation,
extrinsic pathway(GO:0007598) |
blood
coagulation(GO:0007596) |
|
HFL1 |
H factor (complement)-like
1 |
64 |
W88788 |
complement
activation(GO:0006956) |
defense (immune)
response(GO:0006952) |
|
SQLE |
squalene epoxidase |
66 |
W80742 |
steroid
biosynthesis(GO:0006694) |
lipid
metabolism(GO:0006629) |
|
WNT2 |
wingless-type MMTV
integration site family member 2 |
70 |
W80746 |
embryogenesis and
morphogenesis(GO:0007345), signal transduction(GO:0007165), cell-cell
signalling(GO:0007267) |
developmental
processes(GO:0007275) |
|
ASNS |
asparagine
synthetase |
72 |
AA053461 |
asparagine
biosynthesis(GO:0006529) |
amino-acid and
derivative metabolism(GO:0006519) |
|
SMARCB1 |
SWI/SNF related,
matrix associated, actin dependent regulator of chromatin, subfamily b,
member 1 |
73 |
AA026808 |
chromatin
modelling(GO:0006338), negative control of cell proliferation(GO:0008285),
transcription, DNA-dependent(GO:0006351) |
DNA
metabolism(GO:0006259), cell proliferation(GO:0008283),
transcription(GO:0006350) |
|
DHCR24 |
24-dehydrocholesterol
reductase |
74 |
W91979 |
steroid
biosynthesis(GO:0006694) |
lipid
metabolism(GO:0006629) |
|
OSBP2 |
oxysterol binding
protein 2 |
76 |
H52219 |
apoptosis(GO:0006915),
steroid metabolism(GO:0008202) |
cell
death(GO:0008219), lipid metabolism(GO:0006629) |
|
SC5DL |
sterol-C5-desaturase
(fungal ERG3, delta-5-desaturase)-like |
80 |
N91268 |
cholesterol
metabolism(GO:0008203) |
lipid
metabolism(GO:0006629) |
|
|
Homo sapiens cDNA
FLJ13700 fis, clone PLACE2000216, highly similar to SPECTRIN BETA CHAIN,
BRAIN |
82 |
AA055558 |
exocytosis(GO:0006887) |
transport(GO:0006810) |
|
HMGCR |
3-hydroxy-3-methylglutaryl-Coenzyme
A reductase |
85 |
AA053028 |
cholesterol
biosynthesis(GO:0006695)cholesterol biosynthesis(GO:0006695) |
lipid
metabolism(GO:0006629) |
|
CYP1B1 |
cytochrome P450,
subfamily I (dioxin-inducible), polypeptide 1 (glaucoma 3, primary infantile) |
86 |
AA040872 |
xenobiotic
metabolism(GO:0006805), steroid metabolism(GO:0008202), electron transport(GO:0006118) |
lipid
metabolism(GO:0006629) |
|
MID1 |
midline 1
(Opitz/BBB syndrome) |
89 |
W90080 |
developmental
processes(GO:0007275), microtubule-based process(GO:0007017) |
developmental
processes(GO:0007275), cell organization and biogenesis(GO:0006996) |
|
ELF2 |
E74-like factor 2
(ets domain transcription factor) |
92 |
N32165 |
transcription
regulation from Pol II promoter(GO:0006357), cell proliferation(GO:0008283) |
transcription(GO:0006350),
cell proliferation(GO:0008283) |
|
HBP1 |
HMG-box containing
protein 1 |
93 |
AA043938 |
chromatin
modelling(GO:0006338), transcription regulation(GO:0006355),
oncogenesis(GO:0007048) |
DNA
metabolism(GO:0006259), transcription(GO:0006350), oncogenesis(GO:0007048) |
|
|
Homo sapiens cDNA:
FLJ22189 fis, clone HRC01043 |
95 |
AA029774 |
lipid and fatty-acid
transport(GO:0006869), transcription regulation from Pol II
promoter(GO:0006357) |
transport(GO:0006810),
transcription(GO:0006350) |
|
PDE8A |
phosphodiesterase
8A |
96 |
N66765 |
intracellular
signalling cascade(GO:0007242) |
intracellular
signalling cascade(GO:0007242) |
|
SSPN |
sarcospan (Kras
oncogene-associated gene) |
99 |
N21470 |
oncogenesis(GO:0007048),
cell adhesion(GO:0007155) |
oncogenesis(GO:0007048),
cell adhesion(GO:0007155) |
|
PGRMC2 |
progesterone
receptor membrane component 2 |
100 |
AA031314 |
signal
transduction(GO:0007165) |
|
|
ZNF161 |
zinc finger protein
161 |
101 |
AA034054 |
transcription
regulation from Pol II promoter(GO:0006357), defense (immune)
response(GO:0006952) |
transcription(GO:0006350),
defense (immune) response(GO:0006952) |
|
VDUP1 |
upregulated by
1,25-dihydroxyvitamin D-3 |
102 |
AA044633 |
apoptosis(GO:0006915),
redox signal response(GO:0006980), cell proliferation(GO:0008283) |
cell
death(GO:0008219), stress response(GO:0006950), cell
proliferation(GO:0008283) |
|
RABIF |
RAB interacting
factor |
103 |
AA011218 |
non-selective vesicle
transport(GO:0006899), exocytosis(GO:0006887) |
transport(GO:0006810) |
|
TRIP7 |
thyroid hormone
receptor interactor 7 |
104 |
AA029205 |
transcription(GO:0006350),
metabolism(GO:0008152) |
transcription(GO:0006350) |
|
FPGT |
fucose-1-phosphate
guanylyltransferase |
107 |
R38619 |
fucose
metabolism(GO:0006004) |
|
|
|
ESTs, Highly
similar to 1715335A Wee1-like gene [H.sapiens] |
109 |
AA039640 |
mitotic start
control point(GO:0007089), mitotic start control point(GO:0007089), mitotic
G2/M transition(GO:0000086), mitosis(GO:0007067) |
cell cycle(GO:0007049) |
|
SMARCA3 |
SWI/SNF related,
matrix associated, actin dependent regulator of chromatin, subfamily a,
member 3 |
110 |
W70150 |
cell
motility(GO:0006928), defense (immune) response(GO:0006952), blood
coagulation(GO:0007596), chromatin modelling(GO:0006338), transcription
regulation from Pol II promoter(GO:0006357) |
cell
motility(GO:0006928), defense (immune) response(GO:0006952), blood
coagulation(GO:0007596), DNA metabolism(GO:0006259),
transcription(GO:0006350) |
|
|
Homo sapiens clone
24889 mRNA sequence |
123 |
R82488 |
vacuolar
transport(GO:0007034) |
cell organization
and biogenesis(GO:0006996) |
|
ALDH3A2 |
aldehyde
dehydrogenase 3 family, member A2 |
124 |
H63779 |
lipid
metabolism(GO:0006629) |
lipid
metabolism(GO:0006629) |
|
MEIS1 |
Meis1 (mouse)
homolog |
125 |
R15989 |
transcription(GO:0006350),
oncogenesis(GO:0007048) |
transcription(GO:0006350),
oncogenesis(GO:0007048) |
|
F2R |
coagulation factor
II (thrombin) receptor |
128 |
N70450 |
G protein linked
receptor protein signalling pathway(GO:0007186), blood
coagulation(GO:0007596) |
cell surface
receptor linked signal transduction(GO:0007166), blood
coagulation(GO:0007596) |
|
THBS3 |
thrombospondin 3 |
130 |
AA025310 |
heterophilic cell
adhesion(GO:0007157), apoptosis(GO:0006915), positive control of cell
proliferation(GO:0008284), circulation(GO:0008015), cell-cell matrix
adhesion(GO:0007160) |
cell
adhesion(GO:0007155), cell death(GO:0008219), cell proliferation(GO:0008283),
circulation(GO:0008015) |
|
KIT |
v-kit
Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
132 |
W93694 |
transmembrane
receptor protein tyrosine kinase signalling pathway(GO:0007169), defense
(immune) response(GO:0006952), positive control of cell
proliferation(GO:0008284), cell motility(GO:0006928),
anti-apoptosis(GO:0006916), oncogenesis(GO:0007048) |
cell surface
receptor linked signal transduction(GO:0007166), defense (immune)
response(GO:0006952), cell proliferation(GO:0008283), cell
motility(GO:0006928), cell death(GO:0008219), oncogenesis(GO:0007048) |
|
ECM2 |
extracellular
matrix protein 2, female organ and adipocyte specific |
135 |
N79778 |
heterophilic cell
adhesion(GO:0007157), positive control of cell proliferation(GO:0008284),
cell-cell matrix adhesion(GO:0007160) |
cell
adhesion(GO:0007155), cell proliferation(GO:0008283) |
|
HMG2 |
high-mobility group
(nonhistone chromosomal) protein 2 |
139 |
AA019203 |
DNA
unwinding(GO:0006268), DNA unwinding(GO:0006268), transcription regulation
from Pol II promoter(GO:0006357), DNA unwinding(GO:0006268), DNA
packaging(GO:0006323), chromosome organization and biogenesis(GO:0007001) |
cell
cycle(GO:0007049), transcription(GO:0006350), DNA metabolism(GO:0006259),
cell organization and biogenesis(GO:0006996) |
|
GTF2I |
general
transcription factor II, i |
141 |
AA057771 |
transcription,
DNA-dependent(GO:0006351) |
transcription(GO:0006350) |
|
B4-2 |
proline-rich
protein with nuclear targeting signal |
142 |
AA045742 |
chemotaxis(GO:0006935),
cellular defense response(GO:0006968) |
cell
motility(GO:0006928), defense (immune) response(GO:0006952) |
|
TGFBR3 |
transforming growth
factor, beta receptor III (betaglycan, 300kD) |
145 |
H62473 |
apoptosis(GO:0006915),
positive control of cell proliferation(GO:0008284), defense (immune)
response(GO:0006952), TGFbeta receptor signalling pathway(GO:0007179) |
cell
death(GO:0008219), cell proliferation(GO:0008283), defense (immune)
response(GO:0006952), cell surface receptor linked signal
transduction(GO:0007166) |
|
FYN |
FYN oncogene
related to SRC, FGR, YES |
146 |
W45726 |
positive control of
cell proliferation(GO:0008284), intracellular signalling cascade(GO:0007242),
oncogenesis(GO:0007048) |
cell
proliferation(GO:0008283), intracellular signalling cascade(GO:0007242),
oncogenesis(GO:0007048) |
|
PRKCL2 |
protein kinase
C-like 2 |
148 |
AA035285 |
protein kinase
cascade(GO:0007243) |
intracellular
signalling cascade(GO:0007242) |
|
DDIT3 |
DNA-damage-inducible
transcript 3 |
150 |
AA001025 |
transcription
regulation(GO:0006355), cell cycle arrest(GO:0007050)cell cycle
arrest(GO:0007050) |
transcription(GO:0006350),
cell cycle(GO:0007049) |
|
ACF7 |
actin cross-linking
factor |
152 |
AA059074 |
endocytosis(GO:0006897),
non-selective vesicle transport(GO:0006899), actin filament
organization(GO:0007015), actin filament organization(GO:0007015), actin
filament organization(GO:0007015), microtubule stabilization(GO:0007026),
exocytosis(GO:0006887) |
transport(GO:0006810),
cell organization and biogenesis(GO:0006996), cell cycle(GO:0007049) |
|
TAX1BP1 |
Tax1 (human T-cell
leukemia virus type I) binding protein 1 |
153, 78 |
N67978, AA012996 |
transcription
regulation from Pol II promoter(GO:0006357), anti-apoptosis(GO:0006916) |
transcription(GO:0006350),
cell death(GO:0008219) |
|
PDE8B |
phosphodiesterase
8B |
155 |
H17482 |
intracellular
signalling cascade(GO:0007242) |
intracellular
signalling cascade(GO:0007242) |
|
DKFZP564D0764 |
DKFZP564D0764
protein |
156 |
N93862 |
transcription
regulation from Pol II promoter(GO:0006357) |
transcription(GO:0006350) |
|
AHR |
aryl hydrocarbon
receptor |
157 |
W67226 |
committment to
apoptosis(GO:0006920), steroid metabolism(GO:0008202), transcription
regulation from Pol II promoter(GO:0006357), xenobiotic
metabolism(GO:0006805) |
lipid
metabolism(GO:0006629), transcription(GO:0006350) |
|
ACACA |
acetyl-Coenzyme A
carboxylase alpha |
158 |
AA011388 |
fatty acid
biosynthesis(GO:0006633) |
lipid
metabolism(GO:0006629) |
|
CAMK2D |
calcium/calmodulin-dependent
protein kinase (CaM kinase) II delta |
159, 160 |
W45465, AA010624 |
intracellular
signalling cascade(GO:0007242), cell cycle control(GO:0000074) |
intracellular
signalling cascade(GO:0007242), cell cycle(GO:0007049) |
|
KIAA0456 |
KIAA0456 protein |
163 |
N31484 |
actin cytoskeleton
reorganization(GO:0007012), actin cytoskeleton reorganization(GO:0007012),
small GTPase mediated signal transduction(GO:0007264) |
cell organization
and biogenesis(GO:0006996), cell cycle(GO:0007049), intracellular signalling
cascade(GO:0007242) |
|
DPYD |
dihydropyrimidine
dehydrogenase |
164 |
N63511 |
uridine
catabolism(GO:0006218), thymidine catabolism(GO:0006214) |
|
|
DDB2 |
damage-specific DNA
binding protein 2 (48kD) |
167 |
H63374 |
nucleotide-excision
repair(GO:0006289) |
DNA
metabolism(GO:0006259) |
|
KIAA0203 |
likely ortholog of
mouse coiled coil forming protein 1 |
168 |
R44177 |
cytoskeleton
organization and biogenesis(GO:0007010) |
cell organization
and biogenesis(GO:0006996) |
|
ADD3 |
adducin 3 (gamma) |
173 |
AA054129 |
cytoskeleton
organization and biogenesis(GO:0007010) |
cell organization
and biogenesis(GO:0006996) |
|
DDX17 |
DEAD/H
(Asp-Glu-Ala-Asp/His) box polypeptide 17 (72kD) |
177, 221 |
AA010407, R09377 |
RNA
localization(GO:0006403), RNA processing(GO:0006396) |
transcription(GO:0006350) |
|
KIAA1536 |
KIAA1536 protein |
179 |
AA058747 |
chromatin
modelling(GO:0006338), transcription regulation(GO:0006355),
oncogenesis(GO:0007048) |
DNA
metabolism(GO:0006259), transcription(GO:0006350), oncogenesis(GO:0007048) |
|
CLCN3 |
chloride channel 3 |
188 |
N72130 |
cell volume
regulation(GO:0006884), chloride transport(GO:0006821) |
transport(GO:0006810) |
|
TIA1 |
TIA1 cytotoxic
granule-associated RNA-binding protein |
189 |
N79013 |
necrosis(GO:0008220),
killing virus-infected cells(GO:0006926), killing transformed
cells(GO:0006927), defense (immune) response(GO:0006952) |
cell
death(GO:0008219), defense (immune) response(GO:0006952) |
|
CDKN1B |
cyclin-dependent
kinase inhibitor 1B (p27, Kip1) |
192 |
R44858 |
mitotic G1
phase(GO:0000080) |
cell
cycle(GO:0007049) |
|
HSF2 |
heat shock
transcription factor 2 |
196 |
N39221 |
transcription
regulation from Pol II promoter(GO:0006357) |
transcription(GO:0006350) |
|
CDKN2C |
cyclin-dependent
kinase inhibitor 2C (p18, inhibits CDK4) |
204 |
N72115 |
cell cycle
arrest(GO:0007050)negative control of cell proliferation(GO:0008285), cell
cycle arrest(GO:0007050) |
cell
cycle(GO:0007049), cell proliferation(GO:0008283) |
|
TFDP2 |
transcription
factor Dp-2 (E2F dimerization partner 2) |
206 |
W46792 |
transcription
regulation from Pol II promoter(GO:0006357) |
transcription(GO:0006350) |
|
OXR1 |
oxidation
resistance 1 |
207 |
W47204 |
oxidative stress
response(GO:0006979) |
stress
response(GO:0006950) |
|
HNMT |
histamine
N-methyltransferase |
208 |
N67806 |
biogenic amine
metabolism(GO:0006576) |
amino-acid and
derivative metabolism(GO:0006519) |
|
RFX5 |
regulatory factor
X, 5 (influences HLA class II expression) |
211 |
AA040156 |
cellular defense
response(GO:0006968), transcription regulation from Pol II promoter(GO:0006357) |
defense (immune)
response(GO:0006952), transcription(GO:0006350) |
|
NDR |
serine threonine
protein kinase |
215 |
AA043103 |
protein
phosphorylation(GO:0006468) |
protein metabolism
and modification(GO:0006411) |
|
ROR2 |
receptor tyrosine
kinase-like orphan receptor 2 |
217 |
AA024845 |
transmembrane
receptor protein tyrosine kinase signalling pathway(GO:0007169) |
cell surface
receptor linked signal transduction(GO:0007166) |
|
CEBPG |
CCAAT/enhancer
binding protein (C/EBP), gamma |
218 |
AA035360 |
transcription
regulation from Pol II promoter(GO:0006357) |
transcription(GO:0006350) |
|
KIAA0092 |
KIAA0092 gene
product |
219 |
AA046042 |
muscle
contraction(GO:0006936) |
cell
motility(GO:0006928) |
|
PLSCR1 |
phospholipid
scramblase 1 |
220 |
AA056199 |
phospholipid
transfer(GO:0006649), apoptosis(GO:0006915), blood coagulation(GO:0007596) |
lipid
metabolism(GO:0006629), cell death(GO:0008219), blood coagulation(GO:0007596) |
|
ATRX |
alpha
thalassemia/mental retardation syndrome X-linked (RAD54 (S. cerevisiae)
homolog) |
229 |
N22858 |
DNA
packaging(GO:0006323), transcription(GO:0006350), DNA repair(GO:0006281) |
DNA
metabolism(GO:0006259), transcription(GO:0006350) |
|
NARS |
asparaginyl-tRNA
synthetase |
231 |
AA044425 |
asparaginyl-tRNA
biosynthesis(GO:0006421) |
protein metabolism
and modification(GO:0006411) |
|
SDC3 |
syndecan 3 (N-syndecan) |
233 |
R39117 |
cell-cell matrix
adhesion(GO:0007160), substrate-bound cell migration(GO:0006929), cell
surface receptor linked signal transduction(GO:0007166) |
cell
adhesion(GO:0007155), cell motility(GO:0006928), cell surface receptor linked
signal transduction(GO:0007166) |
|
NR1D2 |
nuclear receptor
subfamily 1, group D, member 2 |
234 |
AA013256 |
transcription
regulation from Pol II promoter(GO:0006357) |
transcription(GO:0006350) |
|
FOXF2 |
forkhead box F2 |
237 |
N98485 |
transcription
regulation from Pol II promoter(GO:0006357) |
transcription(GO:0006350) |
|
ZFP36L2 |
zinc finger protein
36, C3H type-like 2 |
238 |
AA039882 |
cell
proliferation(GO:0008283) |
cell
proliferation(GO:0008283) |
|
PPM1B |
protein phosphatase
1B (formerly 2C), magnesium-dependent, beta isoform |
241 |
W73157 |
protein
dephosphorylation(GO:0006470) |
protein metabolism
and modification(GO:0006411) |
|
GARP |
glycoprotein A
repetitions predominant |
242 |
AA026909 |
cell surface
receptor linked signal transduction(GO:0007166) |
cell surface
receptor linked signal transduction(GO:0007166) |
|
TMOD |
tropomodulin |
243 |
AA026182 |
cytoskeleton
organization and biogenesis(GO:0007010) |
cell organization
and biogenesis(GO:0006996) |
|
PSPH |
phosphoserine
phosphatase |
245 |
R00824 |
serine
biosynthesis(GO:0006564) |
amino-acid and
derivative metabolism(GO:0006519) |
|
DAPK1 |
death-associated
protein kinase 1 |
247 |
AA025275 |
apoptosis(GO:0006915) |
cell
death(GO:0008219) |
|
TRABID |
TRAF-binding
protein domain |
248 |
AA005212 |
intracellular
signalling cascade(GO:0007242) |
intracellular
signalling cascade(GO:0007242) |
|
D5S346 |
DNA segment, single
copy probe LNS-CAI/LNS-CAII (deleted in polyposis |
250 |
R05666 |
oncogenesis(GO:0007048) |
oncogenesis(GO:0007048) |
|
CPT1A |
carnitine
palmitoyltransferase I, liver |
253 |
H12318 |
fatty acid
beta-oxidation(GO:0006635) |
lipid
metabolism(GO:0006629) |
|
FBN1 |
fibrillin 1 (Marfan
syndrome) |
255 |
T91093 |
cell-cell matrix
adhesion(GO:0007160), substrate-bound cell migration(GO:0006929) |
cell
adhesion(GO:0007155), cell motility(GO:0006928) |
|
PBX3 |
pre-B-cell leukemia
transcription factor 3 |
257 |
T91871 |
transcription
regulation(GO:0006355) |
transcription(GO:0006350) |
|
EPS15 |
epidermal growth
factor receptor pathway substrate 15 |
258 |
N78949 |
positive control of
cell proliferation(GO:0008284), EGF receptor signalling pathway(GO:0007173) |
cell
proliferation(GO:0008283), cell surface receptor linked signal
transduction(GO:0007166) |
|
PLA2R1 |
phospholipase A2
receptor 1, 180kD |
259 |
W04525 |
cell surface
receptor linked signal transduction(GO:0007166), inflammatory
response(GO:0006954) |
cell surface
receptor linked signal transduction(GO:0007166), defense (immune)
response(GO:0006952) |
|
PACE4 |
paired basic amino
acid cleaving system 4 |
260 |
R55773 |
proteolysis and
peptidolysis(GO:0006508) |
protein metabolism
and modification(GO:0006411) |
|
PDGFRB |
platelet-derived
growth factor receptor, beta polypeptide |
264 |
AA046654 |
transmembrane
receptor protein tyrosine kinase signalling pathway(GO:0007169), positive
control of cell proliferation(GO:0008284), oncogenesis(GO:0007048) |
cell surface
receptor linked signal transduction(GO:0007166), cell proliferation(GO:0008283),
oncogenesis(GO:0007048) |
|
PAPPA |
pregnancy-associated
plasma protein A |
267 |
R37986 |
cell
proliferation(GO:0008283), proteolysis and peptidolysis(GO:0006508) |
cell
proliferation(GO:0008283), protein metabolism and modification(GO:0006411) |
|
CYP2C9 |
cytochrome P450,
subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 9 |
268 |
T40987 |
steroid
metabolism(GO:0008202), xenobiotic metabolism(GO:0006805),
spermatogenesis(GO:0007283), electron transport(GO:0006118), fatty acid
metabolism(GO:0006631), eicosanoid metabolism(GO:0006690) |
lipid
metabolism(GO:0006629), developmental processes(GO:0007275) |
|
FADS2 |
fatty acid
desaturase 2 |
269 |
R12563 |
fatty acid
desaturation(GO:0006636) |
lipid
metabolism(GO:0006629) |
|
SCD |
stearoyl-CoA
desaturase (delta-9-desaturase) |
270, 280, 295 |
H70783, AA039466, AA054956 |
fatty acid
desaturation(GO:0006636) |
lipid
metabolism(GO:0006629) |
|
|
Homo sapiens mRNA
full length insert cDNA clone EUROIMAGE 248114 |
271 |
W86869 |
embryogenesis and
morphogenesis(GO:0007345), oncogenesis(GO:0007048) |
developmental
processes(GO:0007275), oncogenesis(GO:0007048) |
|
C1S |
complement
component 1, s subcomponent |
272 |
AA055521 |
chemotaxis(GO:0006935),
complement activation, classical pathway(GO:0006958) |
cell
motility(GO:0006928), defense (immune) response(GO:0006952) |
|
C1R |
complement component
1, r subcomponent |
273 |
AA041382 |
complement
activation, classical pathway(GO:0006958), chemotaxis(GO:0006935) |
defense (immune)
response(GO:0006952), cell motility(GO:0006928) |
|
LPL |
lipoprotein lipase |
276 |
AA043362 |
heterophilic cell
adhesion(GO:0007157), cell-cell matrix adhesion(GO:0007160), triacylglycerol
metabolism(GO:0006641), membrane lipid metabolism(GO:0006643), lipid and
fatty-acid transport(GO:0006869) |
cell
adhesion(GO:0007155), lipid metabolism(GO:0006629), transport(GO:0006810) |
|
|
Homo sapiens, clone
IMAGE:4296901, mRNA |
277 |
AA026678 |
substrate-bound
cell migration, cell contraction(GO:0006932), mitosis(GO:0007067) |
cell
motility(GO:0006928), cell cycle(GO:0007049) |
|
SPR |
sepiapterin
reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
278 |
AA026314 |
tetrahydrobiopterin
biosynthesis(GO:0006729)tetrahydrobiopterin
biosynthesis(GO:0006729)tetrahydrobiopterin biosynthesis(GO:0006729) |
|
|
P8 |
p8 protein
(candidate of metastasis 1) |
279 |
AA025313 |
positive control of
cell proliferation(GO:0008284) |
cell proliferation(GO:0008283) |
|
PSA |
phosphoserine
aminotransferase |
282 |
AA025800 |
ribosome
biogenesis(GO:0007046), serine biosynthesis(GO:0006564), protein
biosynthesis(GO:0006412) |
cell organization
and biogenesis(GO:0006996), amino-acid and derivative metabolism(GO:0006519),
protein metabolism and modification(GO:0006411) |
|
FDFT1 |
farnesyl-diphosphate
farnesyltransferase 1 |
283 |
AA053173 |
isoprenoid
biosynthesis(GO:0008299), cholesterol biosynthesis(GO:0006695)cholesterol
biosynthesis(GO:0006695) |
lipid
metabolism(GO:0006629) |
|
GJB1 |
gap junction
protein, beta 1, 32kD (connexin 32, Charcot-Marie-Tooth neuropathy, X-linked) |
286 |
AA041403 |
cell
communication(GO:0007154) |
|
|
MLN64 |
steroidogenic acute
regulatory protein related |
287 |
AA045181 |
steroid
metabolism(GO:0008202), cholesterol metabolism(GO:0008203), lipid and
fatty-acid transport(GO:0006869) |
lipid
metabolism(GO:0006629), transport(GO:0006810) |
|
RPL39 |
ribosomal protein
L39 |
288 |
AA045480 |
protein
biosynthesis(GO:0006412), ribosome biogenesis(GO:0007046) |
protein metabolism
and modification(GO:0006411), cell organization and biogenesis(GO:0006996) |
|
IDI1 |
isopentenyl-diphosphate
delta isomerase |
289 |
AA045372 |
isoprenoid
biosynthesis(GO:0008299), cholesterol biosynthesis(GO:0006695)steroid
metabolism(GO:0008202), cholesterol biosynthesis(GO:0006695) |
lipid
metabolism(GO:0006629) |
|
OSR1 |
oxidative-stress
responsive 1 |
290 |
AA039663 |
oxidative stress
response(GO:0006979) |
stress
response(GO:0006950) |
|
INSIG1 |
insulin induced
gene 1 |
291 |
AA046719 |
mitotic start
control point(GO:0007089), mitotic start control point(GO:0007089), positive
control of cell proliferation(GO:0008284) |
cell
cycle(GO:0007049), cell proliferation(GO:0008283) |
|
PPAP2B |
phosphatidic acid
phosphatase type 2B |
297 |
AA045283 |
phospholipid
metabolism(GO:0006644) |
lipid
metabolism(GO:0006629) |
|
AKAP12 |
A kinase (PRKA)
anchor protein (gravin) 12 |
299 |
W68000 |
cell
motility(GO:0006928), intracellular signalling cascade(GO:0007242), actin
cytoskeleton reorganization(GO:0007012)actin cytoskeleton
reorganization(GO:0007012) |
cell
motility(GO:0006928), intracellular signalling cascade(GO:0007242), cell
organization and biogenesis(GO:0006996), cell cycle(GO:0007049) |
|
HEF1 |
enhancer of
filamentation 1 (cas-like docking; Crk-associated substrate related) |
300 |
H65122 |
spindle
assembly(GO:0007051), integrin receptor signal signalling
pathway(GO:0007229), mitotic spindle assembly(GO:0007052), mitotic spindle
assembly(GO:0007052), spindle assembly(GO:0007051), spindle
assembly(GO:0007051), actin filament organization(GO:0007015)actin filament
organization(GO:0007015)cell-cell matrix adhesion(GO:0007160), actin
cytoskeleton reorganization(GO:0007012), actin cytoskeleton
reorganization(GO:0007012), actin filament organization(GO:0007015) |
cell organization
and biogenesis(GO:0006996), cell surface receptor linked signal transduction(GO:0007166),
cell cycle(GO:0007049), cell adhesion(GO:0007155) |
|
PRIM2A |
primase,
polypeptide 2A (58kD) |
304 |
N68268 |
lagging strand
elongation(GO:0006273)DNA replication(GO:0006260), DNA
replication(GO:0006260), DNA replication(GO:0006260), lagging strand
elongation(GO:0006273)DNA replication, priming(GO:0006269), DNA replication,
priming(GO:0006269), DNA replication, priming(GO:0006269), lagging strand
elongation(GO:0006273) |
DNA
metabolism(GO:0006259), cell cycle(GO:0007049) |
|
CIC |
capicua
(Drosophila) homolog |
305 |
AA025540 |
defense (immune)
response(GO:0006952), cell surface receptor linked signal
transduction(GO:0007166) |
defense (immune)
response(GO:0006952), cell surface receptor linked signal
transduction(GO:0007166) |
|
LBR |
lamin B receptor |
306 |
N93426 |
chromosome
organization and biogenesis(GO:0007001), nuclear membrane vesicle binding to
chromatin(GO:0007085) |
cell organization
and biogenesis(GO:0006996), cell cycle(GO:0007049) |
|
CENPE |
centromere protein
E (312kD) |
308 |
W90493 |
mitotic chromosome
segregation(GO:0000070), mitotic chromosome segregation(GO:0000070), mitotic
chromosome movement(GO:0007079), spindle assembly(GO:0007051), spindle
assembly(GO:0007051), spindle assembly(GO:0007051), centromere
binding(GO:0007002) |
cell
cycle(GO:0007049), cell organization and biogenesis(GO:0006996) |
|
MSH2 |
mutS (E. coli)
homolog 2 (colon cancer, nonpolyposis type 1) |
311 |
R43551 |
oncogenesis(GO:0007048),
DNA replication(GO:0006260), DNA replication(GO:0006260), DNA
replication(GO:0006260), mismatch repair(GO:0006298) |
oncogenesis(GO:0007048),
DNA metabolism(GO:0006259), cell cycle(GO:0007049) |
|
XPO1 |
exportin 1 (CRM1,
yeast, homolog) |
312 |
W93537 |
mRNA-nucleus
export(GO:0006406), mRNA-nucleus export(GO:0006406), protein-nucleus
export(GO:0006611)protein-nucleus export(GO:0006611)mRNA-nucleus
export(GO:0006406), protein-nucleus export(GO:0006611) |
transcription(GO:0006350),
transport(GO:0006810), protein targeting(GO:0006605) |
|
POLD3 |
polymerase (DNA
directed), delta 3 |
313 |
W93122 |
nucleotide-excision
repair(GO:0006289), mismatch repair(GO:0006298), mutagenesis(GO:0006280), DNA
recombination(GO:0006310), leading strand elongation(GO:0006272)leading
strand elongation(GO:0006272)base-excision repair(GO:0006284), DNA dependent
DNA replication(GO:0006261), DNA dependent DNA replication(GO:0006261), DNA
dependent DNA replication(GO:0006261), leading strand elongation(GO:0006272) |
DNA
metabolism(GO:0006259), cell cycle(GO:0007049) |
|
FAF1 |
Fas (TNFRSF6)
associated factor 1 |
314 |
R51770 |
induction of
apoptosis via death domain receptors(GO:0008625), intracellular signalling
cascade(GO:0007242) |
cell
death(GO:0008219), intracellular signalling cascade(GO:0007242) |
|
ADAMTS1 |
a disintegrin-like
and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1 |
315 |
AA057170 |
negative control of
cell proliferation(GO:0008285), defense (immune) response(GO:0006952), cell
adhesion inhibition(GO:0007162), circulation(GO:0008015) |
cell
proliferation(GO:0008283), defense (immune) response(GO:0006952), cell
adhesion(GO:0007155), circulation(GO:0008015) |
|
ARF4L |
ADP-ribosylation
factor 4-like |
316 |
AA045331 |
stress
response(GO:0006950), protein ADP-ribosylation(GO:0006471), vesicle
transport(GO:0006905), ER to Golgi transport(GO:0006888), small GTPase
mediated signal transduction(GO:0007264) |
stress
response(GO:0006950), protein metabolism and modification(GO:0006411),
transport(GO:0006810), intracellular signalling cascade(GO:0007242) |
|
BMP1 |
bone morphogenetic
protein 1 |
320 |
AA029677 |
cartilage
condensation(GO:0001502), circulation(GO:0008015), induction of apoptosis by
extracellular signals(GO:0008624), chemotaxis(GO:0006935), proteolysis and
peptidolysis(GO:0006508), positive control of cell proliferation(GO:0008284),
ossification(GO:0001503) |
developmental
processes(GO:0007275), circulation(GO:0008015), cell death(GO:0008219), cell
motility(GO:0006928), protein metabolism and modification(GO:0006411), cell
proliferation(GO:0008283) |
|
PCNA |
proliferating cell
nuclear antigen |
321 |
W73785 |
DNA
replication(GO:0006260), lagging strand elongation(GO:0006273), base-excision
repair(GO:0006284), lagging strand elongation(GO:0006273), lagging strand
elongation(GO:0006273), DNA replication(GO:0006260), DNA
replication(GO:0006260), post-replication repair(GO:0006301), DNA
recombination(GO:0006310), nucleotide-excision repair(GO:0006289), mismatch
repair(GO:0006298), leading strand
elongation(GO:0006272)mutagenesis(GO:0006280), leading strand
elongation(GO:0006272)leading strand elongation(GO:0006272) |
DNA
metabolism(GO:0006259), cell cycle(GO:0007049) |
|
LOC51053 |
geminin |
322 |
N55327 |
DNA replication(GO:0006260),
transcription regulation from Pol II promoter(GO:0006357), DNA
replication(GO:0006260), DNA replication(GO:0006260),
gastrulation(GO:0007369) |
cell
cycle(GO:0007049), transcription(GO:0006350), DNA metabolism(GO:0006259),
developmental processes(GO:0007275) |
|
|
Homo sapiens cDNA:
FLJ22783 fis, clone KAIA1993 |
323 |
W79392 |
neurogenesis(GO:0007399) |
developmental
processes(GO:0007275) |
|
GPC1 |
glypican 1 |
324 |
W72759 |
cell-cell matrix
adhesion(GO:0007160), positive control of cell proliferation(GO:0008284), protein
folding(GO:0006457) |
cell
adhesion(GO:0007155), cell proliferation(GO:0008283), protein metabolism and
modification(GO:0006411) |
|
TOP2A |
topoisomerase (DNA)
II alpha (170kD) |
325 |
N53767 |
chromosome
segregation(GO:0007059), DNA replication(GO:0006260), DNA
replication(GO:0006260), DNA replication(GO:0006260), DNA topological
change(GO:0006265)transcription regulation from Pol II promoter(GO:0006357),
mitotic chromosome condensation(GO:0007076), mitotic chromosome
condensation(GO:0007076), DNA topological change(GO:0006265)DNA topological
change(GO:0006265) |
cell
cycle(GO:0007049), DNA metabolism(GO:0006259), transcription(GO:0006350) |
|
ANLN |
anillin (Drosophila
Scraps homolog), actin binding protein |
327 |
R40626 |
cytokinesis(GO:0007104) |
cell
cycle(GO:0007049) |
|
MAD2L1 |
MAD2 (mitotic
arrest deficient, yeast, homolog)-like 1 |
328 |
R10992 |
anaphase-promoting
complex activation(GO:0007092), mitotic spindle
checkpoint(GO:0007094)anaphase-promoting complex activation(GO:0007092),
mitotic spindle checkpoint(GO:0007094) |
cell cycle(GO:0007049) |
|
C20orf1 |
chromosome 20 open
reading frame 1 |
329 |
H68298 |
cell
proliferation(GO:0008283), cell cycle(GO:0007049) |
cell
proliferation(GO:0008283), cell cycle(GO:0007049) |
|
CENPF |
centromere protein
F (350/400kD, mitosin) |
331 |
T48153 |
centromere binding(GO:0007002),
spindle assembly(GO:0007051), spindle assembly(GO:0007051), spindle
assembly(GO:0007051), mitotic chromosome movement(GO:0007079), mitotic
checkpoint(GO:0007093)mitotic chromosome segregation(GO:0000070), mitotic
chromosome segregation(GO:0000070), mitotic checkpoint(GO:0007093) |
cell
cycle(GO:0007049), cell organization and biogenesis(GO:0006996) |
|
RRM1 |
ribonucleotide
reductase M1 polypeptide |
332 |
N93479 |
purine/pyrimidine
nucleoside diphosphate reduction(GO:0006162), DNA replication(GO:0006260)DNA
replication(GO:0006260)DNA replication(GO:0006260) |
DNA
metabolism(GO:0006259), cell cycle(GO:0007049) |
|
CCNA2 |
cyclin A2 |
333 |
AA001916 |
mitotic G1/S
transition(GO:0000082), mitotic G2 checkpoint(GO:0007095), mitotic G2/M
transition(GO:0000086), mitotic G2 checkpoint(GO:0007095),
mitosis(GO:0007067) |
cell
cycle(GO:0007049) |
|
PMSCL1 |
polymyositis/scleroderma
autoantigen 1 (75kD) |
334 |
R43728 |
ribosome
biogenesis(GO:0007046) |
cell organization
and biogenesis(GO:0006996) |
|
FEN1 |
flap
structure-specific endonuclease 1 |
335 |
H29274 |
DNA
replication(GO:0006260)base-excision repair(GO:0006284), DNA
replication(GO:0006260)DNA recombination(GO:0006310), chromosome
segregation(GO:0007059), DNA repair(GO:0006281), DNA replication(GO:0006260) |
cell
cycle(GO:0007049), DNA metabolism(GO:0006259) |
|
KPNA2 |
karyopherin alpha 2
(RAG cohort 1, importin alpha 1) |
336 |
W86618 |
protein-nucleus
import, docking(GO:0000059)protein-nucleus import,
docking(GO:0000059)protein-nucleus import, docking(GO:0000059) |
transport(GO:0006810),
protein targeting(GO:0006605) |
|
RRM2 |
ribonucleotide
reductase M2 polypeptide |
338 |
AA053076 |
purine/pyrimidine
nucleoside diphosphate reduction(GO:0006162), DNA replication(GO:0006260)DNA
replication(GO:0006260)DNA replication(GO:0006260) |
cell
cycle(GO:0007049), DNA metabolism(GO:0006259) |
|
CDC2 |
cell division cycle
2, G1 to S and G2 to M |
339 |
W74500 |
DNA
replication(GO:0006260), cell cycle checkpoint(GO:0000075), control of
mitosis(GO:0007088), DNA repair(GO:0006281), DNA replication(GO:0006260), DNA
replication(GO:0006260), mitotic G1/S transition(GO:0000082), mitotic G2/M
transition(GO:0000086), mitosis(GO:0007067) |
cell
cycle(GO:0007049), DNA metabolism(GO:0006259) |
|
OCLN |
occludin |
340 |
H94471 |
homophilic cell
adhesion(GO:0007156) |
cell
adhesion(GO:0007155) |
|
CKS2 |
CDC28 protein
kinase 2 |
341 |
AA010065 |
mitotic G1/S
transition(GO:0000082), mitotic start control point(GO:0007089), mitotic G2
checkpoint(GO:0007095), mitotic G2 checkpoint(GO:0007095), regulation of CDK
activity(GO:0000079)regulation of CDK activity(GO:0000079)mitotic G1-specific
transcription(GO:0000114), mitotic G1-specific transcription(GO:0000114),
mitotic G2/M transition(GO:0000086), mitotic start control point(GO:0007089),
regulation of CDK activity(GO:0000079) |
cell
cycle(GO:0007049), transcription(GO:0006350) |
|
CCNB1 |
cyclin B1 |
342 |
N90191 |
mitotic G2/M
transition(GO:0000086), mitotic G2 checkpoint(GO:0007095)mitotic G2
checkpoint(GO:0007095) |
cell
cycle(GO:0007049) |
|
|
Homo sapiens clone
23605 mRNA sequence |
343 |
R39436 |
transcription
regulation from Pol II promoter(GO:0006357) |
transcription(GO:0006350) |
|
PPP4C |
protein phosphatase
4 (formerly X), catalytic subunit |
345 |
AA041370 |
protein
dephosphorylation(GO:0006470), protein kinase cascade(GO:0007243) |
protein metabolism
and modification(GO:0006411), intracellular signalling cascade(GO:0007242) |
|
FOS |
v-fos FBJ murine
osteosarcoma viral oncogene homolog |
348 |
R20750 |
transcription
regulation from Pol II promoter(GO:0006357), positive control of cell
proliferation(GO:0008284), oncogenesis(GO:0007048) |
transcription(GO:0006350),
cell proliferation(GO:0008283), oncogenesis(GO:0007048) |
|
EGR1 |
early growth
response 1 |
349 |
H27557 |
positive control of
cell proliferation(GO:0008284), transcription regulation from Pol II
promoter(GO:0006357) |
cell
proliferation(GO:0008283), transcription(GO:0006350) |
|
NR4A2 |
nuclear receptor
subfamily 4, group A, member 2 |
350 |
N22386 |
mitotic start
control point(GO:0007089), mitotic start control point(GO:0007089),
transcription regulation from Pol II promoter(GO:0006357) |
cell
cycle(GO:0007049), transcription(GO:0006350) |
|
GRO2 |
GRO2 oncogene |
351 |
T70079 |
defense (immune)
response(GO:0006952), chemotaxis(GO:0006935), signal transduction(GO:0007165) |
defense (immune)
response(GO:0006952), cell motility(GO:0006928) |
|
GEM |
GTP-binding protein
overexpressed in skeletal muscle |
352 |
R40776 |
small GTPase
mediated signal transduction(GO:0007264) |
intracellular
signalling cascade(GO:0007242) |
|
PBEF |
pre-B-cell
colony-enhancing factor |
354, 507 |
AA045438, AA047266 |
positive control of
cell proliferation(GO:0008284), humoral defense mechanism(GO:0006959) |
cell
proliferation(GO:0008283), defense (immune) response(GO:0006952) |
|
ZNF295 |
zinc finger protein
295 |
355 |
T50056 |
transcription
regulation from Pol II promoter(GO:0006357) |
transcription(GO:0006350) |
|
DUSP6 |
dual specificity
phosphatase 6 |
356, 384 |
W72836, R59865 |
protein
dephosphorylation(GO:0006470), protein kinase cascade(GO:0007243) |
protein metabolism
and modification(GO:0006411), intracellular signalling cascade(GO:0007242) |
|
TNFAIP3 |
tumor necrosis
factor, alpha-induced protein 3 |
357 |
AA053239 |
transcription regulation
from Pol II promoter(GO:0006357), anti-apoptosis(GO:0006916), defense
(immune) response(GO:0006952) |
transcription(GO:0006350),
cell death(GO:0008219), defense (immune) response(GO:0006952) |
|
HIVEP2 |
human
immunodeficiency virus type I enhancer-binding protein 2 |
358 |
R39209 |
transcription
regulation from Pol II promoter(GO:0006357), defense (immune)
response(GO:0006952) |
transcription(GO:0006350),
defense (immune) response(GO:0006952) |
|
SCYA2 |
small inducible
cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je) |
360 |
T77817 |
chemotaxis(GO:0006935),
defense (immune) response(GO:0006952) |
cell
motility(GO:0006928), defense (immune) response(GO:0006952) |
|
IL1B |
interleukin 1, beta |
362 |
W47101 |
positive control of
cell proliferation(GO:0008284), defense (immune) response(GO:0006952) |
cell
proliferation(GO:0008283), defense (immune) response(GO:0006952) |
|
IL8 |
interleukin 8 |
363 |
W45324 |
chemotaxis(GO:0006935),
humoral defense mechanism(GO:0006959) |
cell
motility(GO:0006928), defense (immune) response(GO:0006952) |
|
ETS2 |
v-ets avian
erythroblastosis virus E26 oncogene homolog 2 |
364, 365 |
R26543, H52671 |
oncogenesis(GO:0007048),
positive control of cell proliferation(GO:0008284), apoptosis(GO:0006915),
transcription regulation from Pol II promoter(GO:0006357), mesoderm
development(GO:0007498) |
oncogenesis(GO:0007048),
cell proliferation(GO:0008283), cell death(GO:0008219),
transcription(GO:0006350), developmental processes(GO:0007275) |
|
CLDN4 |
claudin 4 |
367 |
W74492 |
circulation(GO:0008015),
homophilic cell adhesion(GO:0007156) |
circulation(GO:0008015),
cell adhesion(GO:0007155) |
|
|
ESTs, Highly
similar to S03700 nonhistone chromosomal protein HMG-17 [H.sapiens] |
368 |
AA057727 |
chromatin
architecture(GO:0006325), transcription, DNA-dependent(GO:0006351) |
DNA
metabolism(GO:0006259), transcription(GO:0006350) |
|
VEGF |
vascular
endothelial growth factor |
370 |
AA045836 |
embryogenesis and
morphogenesis(GO:0007345), circulation(GO:0008015), positive control of cell
proliferation(GO:0008284) |
developmental
processes(GO:0007275), circulation(GO:0008015), cell
proliferation(GO:0008283) |
|
|
Homo sapiens clone
IMAGE:451939, mRNA sequence |
371 |
H11257 |
circulation(GO:0008015),
transmembrane receptor protein tyrosine phosphatase signalling
pathway(GO:0007185) |
circulation(GO:0008015),
cell surface receptor linked signal transduction(GO:0007166) |
|
MAT2A |
methionine
adenosyltransferase II, alpha |
372 |
AA039310 |
adenosylmethionine
biosynthesis(GO:0006556)adenosylmethionine biosynthesis(GO:0006556) |
amino-acid and
derivative metabolism(GO:0006519) |
|
THBD |
thrombomodulin |
375 |
AA057068 |
defense (immune)
response(GO:0006952), cell surface receptor linked signal
transduction(GO:0007166), blood coagulation(GO:0007596) |
defense (immune)
response(GO:0006952), cell surface receptor linked signal
transduction(GO:0007166), blood coagulation(GO:0007596) |
|
BMPR2 |
bone morphogenetic
protein receptor, type II (serine/threonine kinase) |
376 |
H96519 |
developmental
processes(GO:0007275), cartilage condensation(GO:0001502), positive control
of cell proliferation(GO:0008284), circulation(GO:0008015) |
developmental
processes(GO:0007275), cell proliferation(GO:0008283),
circulation(GO:0008015) |
|
STC1 |
stanniocalcin 1 |
378 |
R48580 |
phosphorus
transport(GO:0006871), calcium transport(GO:0006816), calcium ion
homeostasis(GO:0006874), circulation(GO:0008015) |
transport(GO:0006810),
ion homeostasis(GO:0006873), circulation(GO:0008015) |
|
RGS4 |
regulator of
G-protein signalling 4 |
379 |
AA007419 |
G protein linked
receptor protein signalling pathway(GO:0007186) |
cell surface
receptor linked signal transduction(GO:0007166) |
|
FCGR2B |
Fc fragment of IgG,
low affinity IIb, receptor for (CD32) |
380 |
R78403 |
defense (immune)
response(GO:0006952), cell surface receptor linked signal
transduction(GO:0007166) |
defense (immune)
response(GO:0006952), cell surface receptor linked signal transduction(GO:0007166) |
|
ICAM1 |
intercellular
adhesion molecule 1 (CD54), human rhinovirus receptor |
382 |
T62835 |
substrate-bound
cell migration(GO:0006929), defense (immune) response(GO:0006952), leukocyte
cell adhesion(GO:0007159) |
cell
motility(GO:0006928), defense (immune) response(GO:0006952), cell
adhesion(GO:0007155) |
|
TMEM2 |
transmembrane
protein 2 |
386 |
N79533 |
transcription,
DNA-dependent(GO:0006351) |
transcription(GO:0006350) |
|
FGF7 |
fibroblast growth
factor 7 (keratinocyte growth factor) |
387 |
AA009609 |
positive control of
cell proliferation(GO:0008284), circulation(GO:0008015) |
cell
proliferation(GO:0008283), circulation(GO:0008015) |
|
FGF2 |
fibroblast growth
factor 2 (basic) |
389 |
W44678 |
positive control of
cell proliferation(GO:0008284), muscle contraction(GO:0006936), circulation(GO:0008015) |
cell
proliferation(GO:0008283), cell motility(GO:0006928), circulation(GO:0008015) |
|
ADRA2C |
adrenergic,
alpha-2C-, receptor |
391 |
T40595 |
G protein linked
receptor protein signalling pathway(GO:0007186) |
cell surface
receptor linked signal transduction(GO:0007166) |
|
FOSL1 |
FOS-like antigen-1 |
392 |
T89996 |
transcription
regulation from Pol II promoter(GO:0006357), positive control of cell
proliferation(GO:0008284) |
transcription(GO:0006350),
cell proliferation(GO:0008283) |
|
SDC2 |
syndecan 2 (heparan
sulfate proteoglycan 1, cell surface-associated, fibroglycan) |
393 |
T79471 |
positive control of
cell proliferation(GO:0008284), cell-cell matrix adhesion(GO:0007160) |
cell
proliferation(GO:0008283), cell adhesion(GO:0007155) |
|
MKI67 |
antigen identified
by monoclonal antibody Ki-67 |
394 |
AA053556 |
M
phase(GO:0000087), positive control of cell proliferation(GO:0008284) |
cell
cycle(GO:0007049), cell proliferation(GO:0008283) |
|
RPS2 |
ribosomal protein
S2 |
395 |
AA057638 |
control of
translational accuracy(GO:0000029), protein synthesis elongation(GO:0006414),
protein biosynthesis(GO:0006412) |
protein metabolism
and modification(GO:0006411) |
|
SDF1 |
stromal
cell-derived factor 1 |
396, 446 |
AA056414, W84538 |
defense (immune)
response(GO:0006952), chemotaxis(GO:0006935), positive control of cell
proliferation(GO:0008284) |
defense (immune)
response(GO:0006952), cell motility(GO:0006928), cell
proliferation(GO:0008283) |
|
RAN |
RAN, member RAS
oncogene family |
397 |
H23544 |
protein-nucleus
import(GO:0006606), nuclear RNA-nucleus export(GO:0006405), nuclear
RNA-nucleus export(GO:0006405), nuclear RNA-nucleus export(GO:0006405),
protein-nucleus import(GO:0006606), nuclear organization and
biogenesis(GO:0006997), small GTPase mediated signal
transduction(GO:0007264), spindle assembly(GO:0007051), spindle
assembly(GO:0007051), spindle assembly(GO:0007051), protein-nucleus
import(GO:0006606), oncogenesis(GO:0007048) |
transport(GO:0006810),
transcription(GO:0006350), cell organization and biogenesis(GO:0006996),
intracellular signalling cascade(GO:0007242), cell cycle(GO:0007049), protein
targeting(GO:0006605), oncogenesis(GO:0007048) |
|
ITGA6 |
integrin, alpha 6 |
398 |
N22383 |
cytoskeletal
anchoring(GO:0007016), cell-cell matrix adhesion(GO:0007160), heterophilic
cell adhesion(GO:0007157), substrate-bound cell migration(GO:0006929),
integrin receptor signal signalling pathway(GO:0007229) |
cell organization
and biogenesis(GO:0006996), cell adhesion(GO:0007155), cell
motility(GO:0006928), cell surface receptor linked signal
transduction(GO:0007166) |
|
ACP1 |
acid phosphatase 1,
soluble |
399 |
AA056583 |
intracellular
signalling cascade(GO:0007242), protein dephosphorylation(GO:0006470) |
intracellular
signalling cascade(GO:0007242), protein metabolism and
modification(GO:0006411) |
|
CDK7 |
cyclin-dependent
kinase 7 (homolog of Xenopus MO15 cdk-activating kinase) |
400 |
AA031961 |
cell cycle
control(GO:0000074), transcription regulation(GO:0006355), DNA
repair(GO:0006281), positive control of cell proliferation(GO:0008284) |
cell
cycle(GO:0007049), transcription(GO:0006350), DNA metabolism(GO:0006259),
cell proliferation(GO:0008283) |
|
SLC25A5 |
solute carrier
family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 |
402 |
AA028950 |
energy
pathways(GO:0006091), ATP/ADP exchange(GO:0006854) |
energy
pathways(GO:0006091), transport(GO:0006810) |
|
RANBP1 |
RAN binding protein
1 |
403 |
N91825 |
small GTPase
mediated signal transduction(GO:0007264), protein-nucleus import(GO:0006606),
spindle assembly(GO:0007051), protein-nucleus import(GO:0006606),
protein-nucleus import(GO:0006606), nuclear RNA-nucleus
export(GO:0006405)spindle assembly(GO:0007051), spindle assembly(GO:0007051),
nuclear RNA-nucleus export(GO:0006405)nuclear RNA-nucleus export(GO:0006405) |
intracellular
signalling cascade(GO:0007242), cell organization and biogenesis(GO:0006996),
transport(GO:0006810), protein targeting(GO:0006605), cell cycle(GO:0007049),
transcription(GO:0006350) |
|
FKBP1A |
FK506-binding
protein 1A (12kD) |
404 |
AA056621 |
peptidylprolyl
isomerase B reaction(GO:0006460), calcium transport(GO:0006816) |
protein metabolism
and modification(GO:0006411), transport(GO:0006810) |
|
NOP56 |
nucleolar protein
(KKE/D repeat) |
405 |
AA056338 |
ribosome
biogenesis(GO:0007046) |
cell organization
and biogenesis(GO:0006996) |
|
|
Homo sapiens mRNA;
cDNA DKFZp434N1221 (from clone DKFZp434N1221) |
406 |
N71362 |
protein
glycosylation(GO:0006486) |
protein metabolism
and modification(GO:0006411) |
|
HSPA8 |
heat shock 70kD
protein 8 |
407 |
AA052965 |
protein
folding(GO:0006457), heat shock response(GO:0006951), unfolded protein
response(GO:0006986) |
protein metabolism
and modification(GO:0006411), stress response(GO:0006950) |
|
CKAP1 |
cytoskeleton-associated
protein 1 |
408 |
AA055578 |
M-phase specific
microtubule process(GO:0000072), spindle assembly(GO:0007051), spindle
assembly(GO:0007051), spindle assembly(GO:0007051), microtubule-based
movement(GO:0007018), M-phase specific microtubule process(GO:0000072),
protein folding(GO:0006457), chaperonine-mediated tubulin
folding(GO:0007022), axon cargo transport(GO:0008088) |
cell
cycle(GO:0007049), cell organization and biogenesis(GO:0006996), protein
metabolism and modification(GO:0006411) |
|
B4GALT1 |
UDP-Gal:betaGlcNAc
beta 1,4- galactosyltransferase, polypeptide 1 |
409 |
AA043796 |
N-linked
glycosylation(GO:0006487), aminosugar metabolism(GO:0006040), glycolipid
metabolism(GO:0006664) |
protein metabolism
and modification(GO:0006411), lipid metabolism(GO:0006629) |
|
ESM1 |
endothelial
cell-specific molecule 1 |
412 |
W46577 |
inflammatory
response(GO:0006954), heterophilic cell adhesion(GO:0007157) |
defense (immune)
response(GO:0006952), cell adhesion(GO:0007155) |
|
DSP |
desmoplakin (DPI,
DPII) |
413 |
AA056401 |
cytoskeletal
anchoring(GO:0007016) |
cell organization
and biogenesis(GO:0006996) |
|
HNT |
neurotrimin |
414, 415 |
N63308, AA037351 |
homophilic cell
adhesion(GO:0007156), heterophilic cell adhesion(GO:0007157), cell surface
receptor linked signal transduction(GO:0007166) |
cell
adhesion(GO:0007155), cell surface receptor linked signal
transduction(GO:0007166) |
|
DNAJB9 |
DnaJ (Hsp40)
homolog, subfamily B, member 9 |
416 |
N40987 |
circulation(GO:0008015) |
circulation(GO:0008015) |
|
OXTR |
oxytocin receptor |
421 |
AA029292 |
cell
proliferation(GO:0008283), smooth muscle contraction(GO:0006939), G protein
linked receptor protein signalling pathway(GO:0007186) |
cell
proliferation(GO:0008283), cell motility(GO:0006928), cell surface receptor
linked signal transduction(GO:0007166) |
|
LOC51660 |
HSPC040 protein |
422 |
N74406 |
heat shock
response(GO:0006951) |
stress
response(GO:0006950) |
|
EBNA1BP2 |
EBNA1-binding
protein 2 |
423 |
AA052986 |
nucleolus
organization and biogenesis(GO:0007000), cell proliferation(GO:0008283) |
cell organization
and biogenesis(GO:0006996), cell proliferation(GO:0008283) |
|
COL4A1 |
collagen, type IV,
alpha 1 |
424 |
R78226 |
cell-cell matrix
adhesion(GO:0007160), cell motility(GO:0006928) |
cell
adhesion(GO:0007155), cell motility(GO:0006928) |
|
HSPB7 |
heat shock 27kD
protein family, member 7 (cardiovascular) |
426 |
AA044617 |
heat shock
response(GO:0006951), protein folding(GO:0006457) |
stress
response(GO:0006950), protein metabolism and modification(GO:0006411) |
|
GCH1 |
GTP cyclohydrolase
1 (dopa-responsive dystonia) |
427 |
N32784 |
tetrahydrobiopterin
biosynthesis(GO:0006729)tetrahydrobiopterin
biosynthesis(GO:0006729)tetrahydrobiopterin biosynthesis(GO:0006729) |
|
|
TIMP3 |
tissue inhibitor of
metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory) |
428 |
AA043969 |
cell
adhesion(GO:0007155), proteolysis and peptidolysis(GO:0006508),
substrate-bound cell migration, cell attachment to substrate(GO:0006931) |
cell
adhesion(GO:0007155), protein metabolism and modification(GO:0006411), cell
motility(GO:0006928) |
|
DDX21 |
DEAD/H (Asp-Glu-Ala-Asp/His)
box polypeptide 21 |
429 |
AA026141 |
ribosome
biogenesis(GO:0007046), positive control of cell proliferation(GO:0008284),
RNA processing(GO:0006396) |
cell organization
and biogenesis(GO:0006996), cell proliferation(GO:0008283), transcription(GO:0006350) |
|
ANPEP |
alanyl (membrane)
aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal
aminopeptidase, CD13, p150) |
430 |
H72904 |
digestion(GO:0007586),
proteolysis and peptidolysis(GO:0006508), substrate-bound cell migration,
cell release from substrate(GO:0006933), circulation(GO:0008015) |
protein metabolism
and modification(GO:0006411), cell motility(GO:0006928),
circulation(GO:0008015) |
|
PPIF |
peptidylprolyl
isomerase F (cyclophilin F) |
432 |
N49296 |
peptidylprolyl
isomerase B reaction(GO:0006460) |
protein metabolism
and modification(GO:0006411) |
|
CTPS |
CTP synthase |
433 |
W44416 |
CTP
biosynthesis(GO:0006241), `de novo` pyrimidine biosynthesis(GO:0006207) |
|
|
FDPS |
farnesyl
diphosphate synthase (farnesyl pyrophosphate synthetase,
dimethylallyltranstransferase, geranyltranstransferase) |
434 |
AA053331 |
cholesterol
biosynthesis(GO:0006695), cholesterol biosynthesis(GO:0006695), isoprenoid
biosynthesis(GO:0008299) |
lipid
metabolism(GO:0006629) |
|
TM4SF1 |
transmembrane 4
superfamily member 1 |
435 |
N47476 |
oxidative stress
response(GO:0006979), metal ion transport(GO:0006823) |
stress
response(GO:0006950), transport(GO:0006810) |
|
HXB |
hexabrachion
(tenascin C, cytotactin) |
436 |
AA045473 |
oncogenesis(GO:0007048),
substrate-bound cell migration(GO:0006929), cell-cell matrix adhesion(GO:0007160) |
oncogenesis(GO:0007048),
cell motility(GO:0006928), cell adhesion(GO:0007155) |
|
DSCR1 |
Down syndrome
critical region gene 1 |
439 |
AA058543 |
circulation(GO:0008015),
developmental processes(GO:0007275), transcription regulation from Pol II
promoter(GO:0006357), intracellular signalling cascade(GO:0007242) |
circulation(GO:0008015),
developmental processes(GO:0007275), transcription(GO:0006350), intracellular
signalling cascade(GO:0007242) |
|
HSPA1A |
heat shock 70kD
protein 1A |
440 |
N67200 |
protein
folding(GO:0006457), protein targeting(GO:0006605), heat shock
response(GO:0006951), intracellular signalling cascade(GO:0007242),
mitochondrial translocation(GO:0006628) |
protein metabolism
and modification(GO:0006411), protein targeting(GO:0006605), stress
response(GO:0006950), intracellular signalling cascade(GO:0007242) |
|
MYO10 |
myosin X |
441 |
W86798 |
intracellular
protein traffic(GO:0006886), cell motility(GO:0006928), cell
adhesion(GO:0007155), cytoskeleton organization and biogenesis(GO:0007010) |
transport(GO:0006810),
cell motility(GO:0006928), cell adhesion(GO:0007155), cell organization and
biogenesis(GO:0006996) |
|
TGM2 |
transglutaminase 2
(C polypeptide, protein-glutamine-gamma-glutamyltransferase) |
443 |
AA045437 |
protein
modification(GO:0006464), stress response(GO:0006950) |
protein metabolism
and modification(GO:0006411), stress response(GO:0006950) |
|
SSR3 |
signal sequence
receptor, gamma (translocon-associated protein gamma) |
444 |
N73309 |
ER
retention(GO:0006621) |
protein
targeting(GO:0006605) |
|
EDG1 |
endothelial
differentiation, sphingolipid G-protein-coupled receptor, 1 |
445 |
N93476 |
G protein linked
receptor protein signalling pathway(GO:0007186) |
cell surface
receptor linked signal transduction(GO:0007166) |
|
WDR1 |
WD repeat domain 1 |
448 |
W19191 |
cell
adhesion(GO:0007155) |
cell adhesion(GO:0007155) |
|
PLOD2 |
procollagen-lysine,
2-oxoglutarate 5-dioxygenase (lysine hydroxylase) 2 |
449 |
N98463 |
protein
modification(GO:0006464) |
protein metabolism
and modification(GO:0006411) |
|
ATP5G1 |
ATP synthase, H+
transporting, mitochondrial F0 complex, subunit c (subunit 9), isoform 1 |
450 |
AA046701 |
energy
pathways(GO:0006091), lipid binding(GO:0006630) |
energy
pathways(GO:0006091), lipid metabolism(GO:0006629) |
|
PFKP |
phosphofructokinase,
platelet |
452 |
AA044444 |
glycolysis(GO:0006096)glycolysis(GO:0006096) |
energy pathways(GO:0006091) |
|
SLC20A1 |
solute carrier
family 20 (phosphate transporter), member 1 |
453 |
AA039313 |
circulation(GO:0008015),
phosphate transport(GO:0006817) |
circulation(GO:0008015),
transport(GO:0006810) |
|
HCS |
cytochrome c |
454 |
AA037369 |
oxidative
phosphorylation(GO:0006119) |
|
|
MT1L |
metallothionein 1L |
456 |
N80129 |
oxidative stress
response(GO:0006979), ion homeostasis(GO:0006873) |
stress
response(GO:0006950), ion homeostasis(GO:0006873) |
|
MT2A |
metallothionein 2A |
457 |
AA037443 |
oxidative stress
response(GO:0006979), ion homeostasis(GO:0006873) |
stress
response(GO:0006950), ion homeostasis(GO:0006873) |
|
ACY1 |
aminoacylase 1 |
458 |
N35315 |
amino-acid and
derivative metabolism(GO:0006519) |
amino-acid and
derivative metabolism(GO:0006519) |
|
CCND1 |
cyclin D1 (PRAD1:
parathyroid adenomatosis 1) |
459 |
T89175 |
regulation of CDK
activity(GO:0000079)oncogenesis(GO:0007048), positive control of cell
proliferation(GO:0008284), regulation of CDK activity(GO:0000079)regulation
of CDK activity(GO:0000079) |
cell
cycle(GO:0007049), oncogenesis(GO:0007048), cell proliferation(GO:0008283) |
|
GPM6B |
glycoprotein M6B |
460 |
N23200 |
developmental
processes(GO:0007275) |
developmental
processes(GO:0007275) |
|
MT1H |
metallothionein 1H |
463 |
H77597 |
oxidative stress
response(GO:0006979), ion homeostasis(GO:0006873) |
stress response(GO:0006950),
ion homeostasis(GO:0006873) |
|
KIAA0165 |
extra spindle
poles, S. cerevisiae, homolog of |
465 |
R42883 |
spindle
assembly(GO:0007051)spindle assembly(GO:0007051)spindle assembly(GO:0007051) |
cell organization
and biogenesis(GO:0006996), cell cycle(GO:0007049) |
|
CDH2 |
cadherin 2, type 1,
N-cadherin (neuronal) |
467 |
W49619 |
homophilic cell
adhesion(GO:0007156), neuronal cell recognition(GO:0008038) |
cell
adhesion(GO:0007155) |
|
SERPIND1 |
serine (or
cysteine) proteinase inhibitor, clade D (heparin cofactor), member 1 |
468 |
N69996 |
defense (immune)
response(GO:0006952), chemotaxis(GO:0006935), blood coagulation, extrinsic
pathway(GO:0007598) |
defense (immune)
response(GO:0006952), cell motility(GO:0006928), blood
coagulation(GO:0007596) |
|
GPD1 |
glycerol-3-phosphate
dehydrogenase 1 (soluble) |
470 |
AA007629 |
energy
pathways(GO:0006091) |
energy
pathways(GO:0006091) |
|
TFPI2 |
tissue factor
pathway inhibitor 2 |
473 |
AA017446 |
blood
coagulation(GO:0007596), cell-cell matrix adhesion(GO:0007160), positive
control of cell proliferation(GO:0008284), inflammatory response(GO:0006954) |
blood
coagulation(GO:0007596), cell adhesion(GO:0007155), cell
proliferation(GO:0008283), defense (immune) response(GO:0006952) |
|
PKM2 |
pyruvate kinase,
muscle |
474 |
AA057761 |
glycolysis(GO:0006096),
glycolysis(GO:0006096), pyruvate metabolism(GO:0006090) |
energy
pathways(GO:0006091) |
|
CCT5 |
chaperonin
containing TCP1, subunit 5 (epsilon) |
475 |
AA053249 |
spindle
assembly(GO:0007051), actin cytoskeleton reorganization(GO:0007012), actin
cytoskeleton reorganization(GO:0007012), spindle assembly(GO:0007051),
spindle assembly(GO:0007051), chaperonine-mediated tubulin
folding(GO:0007022), protein folding(GO:0006457) |
cell organization
and biogenesis(GO:0006996), cell cycle(GO:0007049), protein metabolism and
modification(GO:0006411) |
|
CLTC |
clathrin, heavy
polypeptide (Hc) |
476 |
AA058324 |
endosome
organization and biogenesis(GO:0007032), receptor mediated
endocytosis(GO:0006898), delivery of endocytosed proteins to the
vacuole(GO:0007038) |
cell organization
and biogenesis(GO:0006996), transport(GO:0006810) |
|
RGS12 |
regulator of
G-protein signalling 12 |
477 |
W67134 |
cell surface
receptor linked signal transduction(GO:0007166) |
cell surface
receptor linked signal transduction(GO:0007166) |
|
ACLY |
ATP citrate lyase |
478 |
AA001722 |
acyl-CoA
metabolism(GO:0006637), neurotransmitter synthesis and storage(GO:0001506),
lipid metabolism(GO:0006629) |
lipid
metabolism(GO:0006629) |
|
FLNB |
filamin B, beta
(actin-binding protein-278) |
479 |
AA059125 |
actin
modification(GO:0007013), actin cytoskeleton reorganization(GO:0007012)actin
cytoskeleton reorganization(GO:0007012) |
cell organization
and biogenesis(GO:0006996), cell cycle(GO:0007049) |
|
TPM1 |
tropomyosin 1
(alpha) |
480 |
AA046749 |
cell
motility(GO:0006928), striated muscle contraction regulation(GO:0006942) |
cell motility(GO:0006928) |
|
SERPINE1 |
serine (or
cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator
inhibitor type 1), member 1 |
481 |
AA046659 |
substrate-bound
cell migration, cell attachment to substrate(GO:0006931), cell-cell matrix
adhesion(GO:0007160), blood coagulation(GO:0007596), inflammatory
response(GO:0006954) |
cell
motility(GO:0006928), cell adhesion(GO:0007155), blood
coagulation(GO:0007596), defense (immune) response(GO:0006952) |
|
FLNA |
filamin A, alpha
(actin-binding protein-280) |
482 |
AA046721 |
actin cytoskeleton
reorganization(GO:0007012), actin cytoskeleton reorganization(GO:0007012),
cytoskeletal anchoring(GO:0007016), actin modification(GO:0007013) |
cell organization
and biogenesis(GO:0006996), cell cycle(GO:0007049) |
|
MAP2K3 |
mitogen-activated
protein kinase kinase 3 |
483 |
AA035527 |
protein kinase
cascade(GO:0007243), defense (immune) response(GO:0006952) |
intracellular
signalling cascade(GO:0007242), defense (immune) response(GO:0006952) |
|
NET1 |
neuroepithelial
cell transforming gene 1 |
484 |
AA042891 |
actin cytoskeleton
reorganization(GO:0007012)oncogenesis(GO:0007048), defense (immune)
response(GO:0006952), positive control of cell proliferation(GO:0008284),
small GTPase mediated signal transduction(GO:0007264), actin cytoskeleton
reorganization(GO:0007012) |
cell
cycle(GO:0007049), oncogenesis(GO:0007048), defense (immune)
response(GO:0006952), cell proliferation(GO:0008283), intracellular
signalling cascade(GO:0007242), cell organization and biogenesis(GO:0006996) |
|
UAP1 |
UDP-N-acteylglucosamine
pyrophosphorylase 1 |
485 |
AA040861 |
N-acetylglucosamine
biosynthesis(GO:0006045) |
|
|
PLAUR |
plasminogen
activator, urokinase receptor |
486 |
W49706 |
defense (immune)
response(GO:0006952), cell-cell matrix adhesion(GO:0007160), blood
coagulation(GO:0007596) |
defense (immune)
response(GO:0006952), cell adhesion(GO:0007155), blood
coagulation(GO:0007596) |
|
ZNF222 |
zinc finger protein
222 |
489 |
R49309 |
transcription
regulation from Pol II promoter(GO:0006357) |
transcription(GO:0006350) |
|
F3 |
coagulation factor
III (thromboplastin, tissue factor) |
490 |
R34833 |
blood coagulation,
extrinsic pathway(GO:0007598), defense (immune) response(GO:0006952),
hemostasis(GO:0007599), cell surface receptor linked signal
transduction(GO:0007166) |
blood
coagulation(GO:0007596), defense (immune) response(GO:0006952), cell surface
receptor linked signal transduction(GO:0007166) |
|
PTGS2 |
prostaglandin-endoperoxide
synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
491 |
R80217 |
positive control of
cell proliferation(GO:0008284), prostaglandin metabolism(GO:0006693), intracellular
signalling cascade(GO:0007242), defense (immune) response(GO:0006952),
peroxidase reaction(GO:0006804) |
cell
proliferation(GO:0008283), lipid metabolism(GO:0006629), intracellular
signalling cascade(GO:0007242), defense (immune) response(GO:0006952) |
|
ID3 |
inhibitor of DNA
binding 3, dominant negative helix-loop-helix protein |
492 |
W46413 |
transcription
regulation from Pol II promoter(GO:0006357) |
transcription(GO:0006350) |
|
NR4A1 |
nuclear receptor
subfamily 4, group A, member 1 |
493 |
N94487 |
transcription
regulation from Pol II promoter(GO:0006357), intracellular signalling
cascade(GO:0007242), positive control of cell proliferation(GO:0008284) |
transcription(GO:0006350),
intracellular signalling cascade(GO:0007242), cell proliferation(GO:0008283) |
|
TIEG |
TGFB inducible
early growth response |
494 |
AA045731 |
transcription
regulation from Pol II promoter(GO:0006357), embryogenesis and
morphogenesis(GO:0007345), positive control of cell
proliferation(GO:0008284), cell surface receptor linked signal
transduction(GO:0007166) |
transcription(GO:0006350),
developmental processes(GO:0007275), cell proliferation(GO:0008283), cell
surface receptor linked signal transduction(GO:0007166) |
|
CTGF |
connective tissue
growth factor |
496 |
AA044993 |
enzyme linked
receptor protein signalling pathway(GO:0007167), chemotaxis(GO:0006935),
positive control of cell proliferation(GO:0008284) |
cell surface
receptor linked signal transduction(GO:0007166), cell motility(GO:0006928),
cell proliferation(GO:0008283) |
|
CDKN1A |
cyclin-dependent
kinase inhibitor 1A (p21, Cip1) |
499 |
N23941 |
cell cycle
arrest(GO:0007050), negative control of cell proliferation(GO:0008285), DNA
damage checkpoint(GO:0000077)cell cycle arrest(GO:0007050), DNA damage
checkpoint(GO:0000077) |
cell
cycle(GO:0007049), cell proliferation(GO:0008283), stress
response(GO:0006950) |
|
RPS5 |
ribosomal protein
S5 |
500 |
AA057826 |
protein
biosynthesis(GO:0006412), ribosome biogenesis(GO:0007046) |
protein metabolism
and modification(GO:0006411), cell organization and biogenesis(GO:0006996) |
|
NR4A3 |
nuclear receptor
subfamily 4, group A, member 3 |
501 |
W42606 |
positive control of
cell proliferation(GO:0008284), transcription regulation from Pol II
promoter(GO:0006357) |
cell
proliferation(GO:0008283), transcription(GO:0006350) |
|
BHLHB2 |
basic
helix-loop-helix domain containing, class B, 2 |
502 |
AA026120 |
transcription
regulation from Pol II promoter(GO:0006357) |
transcription(GO:0006350) |
|
JUNB |
jun B
proto-oncogene |
504 |
N99070 |
transcription
regulation from Pol II promoter(GO:0006357), JNK cascade(GO:0007254),
positive control of cell proliferation(GO:0008284), oncogenesis(GO:0007048) |
transcription(GO:0006350),
intracellular signalling cascade(GO:0007242), cell proliferation(GO:0008283),
oncogenesis(GO:0007048) |
|
MCL1 |
myeloid cell
leukemia sequence 1 (BCL2-related) |
505, 506 |
AA044235, R77289 |
intracellular
signalling cascade(GO:0007242), anti-apoptosis(GO:0006916), defense (immune)
response(GO:0006952) |
intracellular
signalling cascade(GO:0007242), cell death(GO:0008219), defense (immune)
response(GO:0006952) |
|
EDN1 |
endothelin 1 |
508 |
H11003 |
circulation(GO:0008015),
blood pressure regulation(GO:0008217) |
circulation(GO:0008015) |
|
IL6 |
interleukin 6 (interferon, beta 2) |
509 |
N98591 |
defense (immune)
response(GO:0006952), positive control of cell proliferation(GO:0008284) |
defense (immune) response(GO:0006952),
cell proliferation(GO:0008283) |
|
SGK |
serum/glucocorticoid
regulated kinase |
511 |
AA057359 |
defense (immune)
response(GO:0006952), protein phosphorylation(GO:0006468), intracellular
signalling cascade(GO:0007242) |
defense (immune)
response(GO:0006952), protein metabolism and modification(GO:0006411),
intracellular signalling cascade(GO:0007242) |
|
COPEB |
core promoter
element binding protein |
512 |
AA055585 |
transcription
regulation from Pol II promoter(GO:0006357) |
transcription(GO:0006350) |
|
SV2B |
synaptic vesicle
protein 2B homolog |
513 |
AA016304 |
synaptic
transmission(GO:0007268) |
|
|
UROS |
uroporphyrinogen
III synthase (congenital erythropoietic porphyria) |
515 |
W88807 |
heme
biosynthesis(GO:0006783), uroporphyrinogen III biosynthesis(GO:0006780) |
|